Guide to the Human Genome
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Search of human proteins with 15029518

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15029518 inducible T-cell co-stimulator precursor [Homo
sapiens]
         (199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15029518 inducible T-cell co-stimulator precursor [Homo sapiens]   421   e-118
gi|5453611 CD28 antigen precursor [Homo sapiens]                       54   1e-07
gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform ...    32   0.27 
gi|134288915 myosin IIIB isoform 1 [Homo sapiens]                      31   0.61 
gi|134288892 myosin IIIB isoform 2 [Homo sapiens]                      31   0.61 
gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform ...    30   1.0  
gi|148596992 heart alpha-kinase [Homo sapiens]                         30   1.4  
gi|38569482 hypothetical protein LOC57535 [Homo sapiens]               30   1.4  
gi|45594310 olfactory receptor, family 5, subfamily V, member 1 ...    29   2.3  
gi|57863312 uridine-cytidine kinase 1-like 1 [Homo sapiens]            28   3.9  
gi|188497623 neuromedin U receptor 1 [Homo sapiens]                    28   5.1  
gi|4504023 glycine receptor, beta [Homo sapiens]                       28   6.7  
gi|186928847 cirhin [Homo sapiens]                                     28   6.7  
gi|24431977 XK, Kell blood group complex subunit-related family,...    28   6.7  
gi|27883876 T cell immunoreceptor with Ig and ITIM domains [Homo...    27   8.8  

>gi|15029518 inducible T-cell co-stimulator precursor [Homo sapiens]
          Length = 199

 Score =  421 bits (1082), Expect = e-118
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQ 60
           MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQ
Sbjct: 1   MKSGLWYFFLFCLRIKVLTGEINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQ 60

Query: 61  ILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFK 120
           ILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFK
Sbjct: 61  ILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFK 120

Query: 121 VTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEY 180
           VTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEY
Sbjct: 121 VTLTGGYLHIYESQLCCQLKFWLPIGCAAFVVVCILGCILICWLTKKKYSSSVHDPNGEY 180

Query: 181 MFMRAVNTAKKSRLTDVTL 199
           MFMRAVNTAKKSRLTDVTL
Sbjct: 181 MFMRAVNTAKKSRLTDVTL 199


>gi|5453611 CD28 antigen precursor [Homo sapiens]
          Length = 220

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 9/141 (6%)

Query: 30  MFIFHNGGVQILCKYPDIV--QQFKMQLLKGGQILCDLTKTKGSGNT---VSIKSLKFCH 84
           M + ++  V + CKY   +  ++F+  L KG     ++    G+ +    V  K+   C 
Sbjct: 28  MLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCD 87

Query: 85  SQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPF--KVTLTGGYLHIYESQLCCQLKFW 142
            +L N SV+F+L NL  +  + YFC + +  PPP+       G  +H+    LC    F 
Sbjct: 88  GKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLF- 146

Query: 143 LPIGCAAFVVVCILGCILICW 163
            P     F V+ ++G +L C+
Sbjct: 147 -PGPSKPFWVLVVVGGVLACY 166


>gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform a
           precursor [Homo sapiens]
          Length = 223

 Score = 32.3 bits (72), Expect = 0.27
 Identities = 27/142 (19%), Positives = 55/142 (38%), Gaps = 9/142 (6%)

Query: 36  GGVQILCKY--PDIVQQFKMQLLK--GGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNS 91
           G    +C+Y  P    + ++ +L+    Q+      T   GN ++      C    S N 
Sbjct: 52  GIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQ 111

Query: 92  VSFFLYNLDHSHANYYFCNLSIFDPPPFKVTL-TGGYLHIYESQLCCQLKFWL----PIG 146
           V+  +  L       Y C + +  PPP+ + +  G  +++ + + C    F L     + 
Sbjct: 112 VNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVS 171

Query: 147 CAAFVVVCILGCILICWLTKKK 168
              F    +L  + +  + KK+
Sbjct: 172 SGLFFYSFLLTAVSLSKMLKKR 193


>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
          Length = 1314

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 8/76 (10%)

Query: 38  VQILCKYPDIVQQF----KMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVS 93
           +Q L  +P++V+ +    K     GGQ+   L    G   T  +K L  C  +L    +S
Sbjct: 75  LQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMIS 134

Query: 94  FFLY----NLDHSHAN 105
           + LY     L H H N
Sbjct: 135 YILYGALLGLQHLHNN 150


>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
          Length = 1341

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 8/76 (10%)

Query: 38  VQILCKYPDIVQQF----KMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVS 93
           +Q L  +P++V+ +    K     GGQ+   L    G   T  +K L  C  +L    +S
Sbjct: 75  LQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMIS 134

Query: 94  FFLY----NLDHSHAN 105
           + LY     L H H N
Sbjct: 135 YILYGALLGLQHLHNN 150


>gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform b
           precursor [Homo sapiens]
          Length = 174

 Score = 30.4 bits (67), Expect = 1.0
 Identities = 20/95 (21%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query: 36  GGVQILCKY--PDIVQQFKMQLLK--GGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNS 91
           G    +C+Y  P    + ++ +L+    Q+      T   GN ++      C    S N 
Sbjct: 52  GIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQ 111

Query: 92  VSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGG 126
           V+  +  L       Y C + +  PPP+ + +  G
Sbjct: 112 VNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNG 146


>gi|148596992 heart alpha-kinase [Homo sapiens]
          Length = 2170

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 13/48 (27%), Positives = 27/48 (56%)

Query: 29   EMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVS 76
            EMF  H+G V++ C++ +I +   +   K  + +  + ++ G  +TVS
Sbjct: 1795 EMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVS 1842


>gi|38569482 hypothetical protein LOC57535 [Homo sapiens]
          Length = 1013

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 6/45 (13%)

Query: 135 LCCQLKFWLPIGCAAFVVVCILGCILICWLTKK------KYSSSV 173
           +C  + FWL +G +A     IL  +L C+  KK      KYS  V
Sbjct: 901 ICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNQKLEYKYSKLV 945


>gi|45594310 olfactory receptor, family 5, subfamily V, member 1
           [Homo sapiens]
          Length = 321

 Score = 29.3 bits (64), Expect = 2.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 20/90 (22%)

Query: 73  NTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYE 132
           N+V    L FC     NN +            NY+FC++     PP  + L+ G   + E
Sbjct: 155 NSVVHTVLTFCLPFCGNNQI------------NYFFCDI-----PPLLI-LSCGNTSVNE 196

Query: 133 SQLCCQLKF--WLPIGCAAFVVVCILGCIL 160
             L     F  W P  C     +CI+  IL
Sbjct: 197 LALLSTGVFIGWTPFLCIVLSYICIISTIL 226


>gi|57863312 uridine-cytidine kinase 1-like 1 [Homo sapiens]
          Length = 548

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 40  ILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSL-KFCHSQLSNNSVS 93
           ++ +Y   V+    Q ++    L D+   +GSGNTV+I  + +  HSQL    +S
Sbjct: 252 VIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEERELS 306


>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
          Length = 426

 Score = 28.1 bits (61), Expect = 5.1
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 10/86 (11%)

Query: 105 NYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQLKFWLPIG-----CAAFVVVCILGCI 159
           NYY  +L++ D     V L G  L +YE  +     F L +G        F +VC+   +
Sbjct: 96  NYYLFSLAVSD---LLVLLVGLPLELYE--MWHNYPFLLGVGGCYFRTLLFEMVCLASVL 150

Query: 160 LICWLTKKKYSSSVHDPNGEYMFMRA 185
            +  L+ ++Y + VH      M  RA
Sbjct: 151 NVTALSVERYVAVVHPLQARSMVTRA 176


>gi|4504023 glycine receptor, beta [Homo sapiens]
          Length = 497

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 24/101 (23%), Positives = 37/101 (36%), Gaps = 13/101 (12%)

Query: 27  NYEMFIFHNGGVQI-------------LCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGN 73
           N  +FIF +G V +             L  +P   Q+ KMQL   G    DL     SG+
Sbjct: 160 NILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGD 219

Query: 74  TVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIF 114
            V ++ +      +    + +      +    YY C   IF
Sbjct: 220 PVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIF 260


>gi|186928847 cirhin [Homo sapiens]
          Length = 686

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 67  KTKGSGNTVSIKSLKFCHSQLSNNSVS-FFLYNLDHSHAN 105
           KTKG  N +    +  C S ++ ++VS FFLY L++ H N
Sbjct: 386 KTKGPENIIC-SCISPCGSWIAYSTVSRFFLYRLNYEHDN 424


>gi|24431977 XK, Kell blood group complex subunit-related family,
           member 8 [Homo sapiens]
          Length = 395

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 10/26 (38%), Positives = 14/26 (53%)

Query: 139 LKFWLPIGCAAFVVVCILGCILICWL 164
           L+ WLP+GC  F +   L  +   WL
Sbjct: 316 LQLWLPVGCGCFFLGLALRLVYYHWL 341


>gi|27883876 T cell immunoreceptor with Ig and ITIM domains [Homo
           sapiens]
          Length = 244

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 34/145 (23%), Positives = 57/145 (39%), Gaps = 25/145 (17%)

Query: 57  KGGQIL--CDLTKTKGSGNTVSIKS----LKFCHSQLS-------------NNSVSFFLY 97
           KGG I+  C L+ T      V+ +     L  C++ L                 +   L 
Sbjct: 37  KGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQ 96

Query: 98  NLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQ-LKFWLPI--GCAAFVVVC 154
           +L  +    YFC   I+   P        +L + ES +     +F +P+    AA +VV 
Sbjct: 97  SLTVNDTGEYFC---IYHTYPDGAYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVI 153

Query: 155 ILGCILICWLTKKKYSSSVHDPNGE 179
               I++  LT+KK +  +H   G+
Sbjct: 154 CTAVIVVVALTRKKKALRIHSVEGD 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,750,746
Number of Sequences: 37866
Number of extensions: 326784
Number of successful extensions: 769
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 762
Number of HSP's gapped (non-prelim): 15
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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