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Search of human proteins with 110227631
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110227631 synaptotagmin-like 3 [Homo sapiens]
(542 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110227631 synaptotagmin-like 3 [Homo sapiens] 1118 0.0
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 221 1e-57
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 221 1e-57
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 220 3e-57
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 213 3e-55
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 213 3e-55
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 195 8e-50
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 195 8e-50
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 195 8e-50
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 195 1e-49
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens] 195 1e-49
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens] 195 1e-49
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 195 1e-49
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 194 1e-49
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens] 194 2e-49
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 181 2e-45
gi|6005997 double C2-like domains, beta [Homo sapiens] 81 2e-15
gi|45504376 synaptotagmin VI [Homo sapiens] 80 4e-15
gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens] 80 6e-15
gi|211059429 synaptotagmin II [Homo sapiens] 80 6e-15
gi|31543670 synaptotagmin II [Homo sapiens] 80 6e-15
gi|92859638 synaptotagmin V [Homo sapiens] 79 8e-15
gi|28376627 synaptotagmin IX [Homo sapiens] 78 2e-14
gi|39752671 synaptotagmin X [Homo sapiens] 78 2e-14
gi|209447073 synaptotagmin I [Homo sapiens] 77 3e-14
gi|5032139 synaptotagmin I [Homo sapiens] 77 3e-14
gi|209447070 synaptotagmin I [Homo sapiens] 77 3e-14
gi|238550198 synaptotagmin III [Homo sapiens] 75 1e-13
gi|238550196 synaptotagmin III [Homo sapiens] 75 1e-13
gi|14150054 synaptotagmin III [Homo sapiens] 75 1e-13
>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
Length = 542
Score = 1118 bits (2891), Expect = 0.0
Identities = 542/542 (100%), Positives = 542/542 (100%)
Query: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60
MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE
Sbjct: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60
Query: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120
KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF
Sbjct: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120
Query: 121 YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDIL 180
YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDIL
Sbjct: 121 YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDIL 180
Query: 181 KPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTG 240
KPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTG
Sbjct: 181 KPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTG 240
Query: 241 EIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRN 300
EIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRN
Sbjct: 241 EIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRN 300
Query: 301 TVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSF 360
TVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSF
Sbjct: 301 TVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSF 360
Query: 361 RWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLG 420
RWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLG
Sbjct: 361 RWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLG 420
Query: 421 AKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQS 480
AKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQS
Sbjct: 421 AKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQS 480
Query: 481 SLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLV 540
SLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLV
Sbjct: 481 SLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLV 540
Query: 541 LH 542
LH
Sbjct: 541 LH 542
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 221 bits (563), Expect = 1e-57
Identities = 144/387 (37%), Positives = 209/387 (54%), Gaps = 26/387 (6%)
Query: 172 RKVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMG 231
R S P L + E+ + S + ++ Q ++ + G SL S+ S +E G
Sbjct: 344 RSKSVPGALDKDSLEETEESIDALVSSQLSTNTHR----LASGLSTTSLNSMMSVYSETG 399
Query: 232 NFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQG 291
++ N V+GEI I YC+KT L I +K C+NLA G+EKK++ + YVK+YLLPD+S
Sbjct: 400 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 459
Query: 292 KRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWD 351
KRKT ++ T +P F ETLKY ++ QL TR LQ+SVWH R FLGEV IP +W+
Sbjct: 460 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518
Query: 352 FEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSR-----PRKLQ-----EA 401
FE+ T + W L+ K E D Q GELTV + + P P +LQ +
Sbjct: 519 FENPTDE---WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKK 575
Query: 402 QEGTDQPSLHGQLCLV-VLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQA 459
+ + P + G + V + AKNL V+ GT +SFVKG L D + + K+ V++K
Sbjct: 576 GKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSV 635
Query: 460 CPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGG----- 514
PQW H+F+FSG+ P ++ LELT+WD+ F N LGG RL S + G
Sbjct: 636 NPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN-IFLGGVRLNSGSGVSHGKNVDWM 694
Query: 515 DACSLSKLQWQKVLSSPNLWTDMTLVL 541
D+ + WQK+ ++P + L+L
Sbjct: 695 DSQGEEQRLWQKMANNPGTPFEGVLML 721
Score = 102 bits (254), Expect = 9e-22
Identities = 72/237 (30%), Positives = 110/237 (46%), Gaps = 27/237 (11%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64
I+LS L + E+E IL VL RD+ ++ E++R RKLK L + + K + + C
Sbjct: 8 INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQ--QEASRVCV 65
Query: 65 RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124
C + LG + RG C+ CS RVC +CRV +WKCTVC + ++I TGEWF+EE+
Sbjct: 66 HCHRNLGLIFDRGDPCQACSLRVCRECRV-AGPNGSWKCTVCDKIAQLRIITGEWFFEEK 124
Query: 125 AKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLN 184
AK+F K V G V +S RSPG + +
Sbjct: 125 AKRF----KQVNVLG------------------TDVVRQSILRRSPGAEEVQSQ--EQTR 160
Query: 185 QEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGE 241
Q+ K T+P+ ++ P FR + I + T+ G + ++ G+
Sbjct: 161 QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQ 217
>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 221 bits (563), Expect = 1e-57
Identities = 144/387 (37%), Positives = 209/387 (54%), Gaps = 26/387 (6%)
Query: 172 RKVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMG 231
R S P L + E+ + S + ++ Q ++ + G SL S+ S +E G
Sbjct: 344 RSKSVPGALDKDSLEETEESIDALVSSQLSTNTHR----LASGLSTTSLNSMMSVYSETG 399
Query: 232 NFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQG 291
++ N V+GEI I YC+KT L I +K C+NLA G+EKK++ + YVK+YLLPD+S
Sbjct: 400 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 459
Query: 292 KRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWD 351
KRKT ++ T +P F ETLKY ++ QL TR LQ+SVWH R FLGEV IP +W+
Sbjct: 460 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 518
Query: 352 FEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSR-----PRKLQ-----EA 401
FE+ T + W L+ K E D Q GELTV + + P P +LQ +
Sbjct: 519 FENPTDE---WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKK 575
Query: 402 QEGTDQPSLHGQLCLV-VLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQA 459
+ + P + G + V + AKNL V+ GT +SFVKG L D + + K+ V++K
Sbjct: 576 GKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSV 635
Query: 460 CPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGG----- 514
PQW H+F+FSG+ P ++ LELT+WD+ F N LGG RL S + G
Sbjct: 636 NPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN-IFLGGVRLNSGSGVSHGKNVDWM 694
Query: 515 DACSLSKLQWQKVLSSPNLWTDMTLVL 541
D+ + WQK+ ++P + L+L
Sbjct: 695 DSQGEEQRLWQKMANNPGTPFEGVLML 721
Score = 102 bits (254), Expect = 9e-22
Identities = 72/237 (30%), Positives = 110/237 (46%), Gaps = 27/237 (11%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64
I+LS L + E+E IL VL RD+ ++ E++R RKLK L + + K + + C
Sbjct: 8 INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQ--QEASRVCV 65
Query: 65 RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124
C + LG + RG C+ CS RVC +CRV +WKCTVC + ++I TGEWF+EE+
Sbjct: 66 HCHRNLGLIFDRGDPCQACSLRVCRECRV-AGPNGSWKCTVCDKIAQLRIITGEWFFEEK 124
Query: 125 AKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLN 184
AK+F K V G V +S RSPG + +
Sbjct: 125 AKRF----KQVNVLG------------------TDVVRQSILRRSPGAEEVQSQ--EQTR 160
Query: 185 QEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGE 241
Q+ K T+P+ ++ P FR + I + T+ G + ++ G+
Sbjct: 161 QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQ 217
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 220 bits (560), Expect = 3e-57
Identities = 136/340 (40%), Positives = 192/340 (56%), Gaps = 22/340 (6%)
Query: 219 SLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPY 278
SL S+ S +E G++ N V+GEI I YC+KT L I +K C+NLA G+EKK++ + Y
Sbjct: 409 SLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAY 468
Query: 279 VKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRV 338
VK+YLLPD+S KRKT ++ T +P F ETLKY ++ QL TR LQ+SVWH R
Sbjct: 469 VKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNS 527
Query: 339 FLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSR---- 394
FLGEV IP +W+FE+ T + W L+ K E D Q GELTV + + P
Sbjct: 528 FLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLML 584
Query: 395 -PRKLQ-----EAQEGTDQPSLHGQLCLV-VLGAKNL-PVRPDGTLNSFVKGCLTLPDQQ 446
P +LQ + + + P + G + V + AKNL V+ GT +SFVKG L D +
Sbjct: 585 PPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSK 644
Query: 447 KLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGS 506
+ K+ V++K PQW H+F+FSG+ P ++ LELT+WD+ F N LGG RL S
Sbjct: 645 ATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN-IFLGGVRLNS 703
Query: 507 KGDTAVGG-----DACSLSKLQWQKVLSSPNLWTDMTLVL 541
+ G D+ + WQK+ ++P + L+L
Sbjct: 704 GSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLML 743
Score = 102 bits (254), Expect = 9e-22
Identities = 72/237 (30%), Positives = 110/237 (46%), Gaps = 27/237 (11%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64
I+LS L + E+E IL VL RD+ ++ E++R RKLK L + + K + + C
Sbjct: 8 INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQ--QEASRVCV 65
Query: 65 RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124
C + LG + RG C+ CS RVC +CRV +WKCTVC + ++I TGEWF+EE+
Sbjct: 66 HCHRNLGLIFDRGDPCQACSLRVCRECRV-AGPNGSWKCTVCDKIAQLRIITGEWFFEEK 124
Query: 125 AKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLN 184
AK+F K V G V +S RSPG + +
Sbjct: 125 AKRF----KQVNVLG------------------TDVVRQSILRRSPGAEEVQSQ--EQTR 160
Query: 185 QEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGE 241
Q+ K T+P+ ++ P FR + I + T+ G + ++ G+
Sbjct: 161 QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQ 217
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 213 bits (543), Expect = 3e-55
Identities = 141/389 (36%), Positives = 203/389 (52%), Gaps = 40/389 (10%)
Query: 172 RKVSAPDILKPLNQEDPKCSTNPILK-------QQNLPSSPAPSTIFSGGFRHGSLISID 224
R S P + + +E+ + + ++K + ++ S + STI GS++SI
Sbjct: 293 RSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345
Query: 225 STCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLL 284
S E G+F N VTG I F++ Y +T SL + +K C LAY +E KK+ NPYVKTYLL
Sbjct: 346 S---EAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402
Query: 285 PDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVI 344
PD+S QGKRKT ++R+T++P + ETL+Y++ + L R LQ SVWH G R FLGE
Sbjct: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462
Query: 345 IPLATWDFEDSTTQSFRWHPLRAK-AEKYEDSVPQSNGELTVRAKLVLPSR-----PRKL 398
I + +W + PL K + + +P GEL V K + S+ RK
Sbjct: 463 IQMDSWKLDKKLDHCL---PLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519
Query: 399 QEAQEGTDQPSLHGQLCLVVLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRK 457
+ EG G+L + + AKNL + GT +SFVKG L + + K+PV++K
Sbjct: 520 SKGGEG-------GELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKK 572
Query: 458 QACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTAV 512
P + H+FV++GV L+ LELTVWD+ ND LGG RLG S G+
Sbjct: 573 TLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASND-FLGGVRLGVGTGISNGEVVD 631
Query: 513 GGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
D+ WQK+ P W + TL L
Sbjct: 632 WMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
Score = 119 bits (299), Expect = 5e-27
Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 17/162 (10%)
Query: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60
M++ +DLS L E E++ IL VL RD+ V+ +E+R R+LK L ++ KGAK + +
Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
Query: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120
+ CARCQ+ LG L + CRGC+H VC CR+ W+C VC ++ +K TG+WF
Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRI-QESNGTWRCKVCAKEIELKKATGDWF 119
Query: 121 YEERAKKF----------------PTGGKHETVGGQLLQSYQ 146
Y+++ +F P K ETVG LL Q
Sbjct: 120 YDQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQ 161
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 213 bits (543), Expect = 3e-55
Identities = 141/389 (36%), Positives = 203/389 (52%), Gaps = 40/389 (10%)
Query: 172 RKVSAPDILKPLNQEDPKCSTNPILK-------QQNLPSSPAPSTIFSGGFRHGSLISID 224
R S P + + +E+ + + ++K + ++ S + STI GS++SI
Sbjct: 293 RSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345
Query: 225 STCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLL 284
S E G+F N VTG I F++ Y +T SL + +K C LAY +E KK+ NPYVKTYLL
Sbjct: 346 S---EAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402
Query: 285 PDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVI 344
PD+S QGKRKT ++R+T++P + ETL+Y++ + L R LQ SVWH G R FLGE
Sbjct: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462
Query: 345 IPLATWDFEDSTTQSFRWHPLRAK-AEKYEDSVPQSNGELTVRAKLVLPSR-----PRKL 398
I + +W + PL K + + +P GEL V K + S+ RK
Sbjct: 463 IQMDSWKLDKKLDHCL---PLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519
Query: 399 QEAQEGTDQPSLHGQLCLVVLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRK 457
+ EG G+L + + AKNL + GT +SFVKG L + + K+PV++K
Sbjct: 520 SKGGEG-------GELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKK 572
Query: 458 QACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTAV 512
P + H+FV++GV L+ LELTVWD+ ND LGG RLG S G+
Sbjct: 573 TLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASND-FLGGVRLGVGTGISNGEVVD 631
Query: 513 GGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
D+ WQK+ P W + TL L
Sbjct: 632 WMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
Score = 119 bits (299), Expect = 5e-27
Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 17/162 (10%)
Query: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60
M++ +DLS L E E++ IL VL RD+ V+ +E+R R+LK L ++ KGAK + +
Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
Query: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120
+ CARCQ+ LG L + CRGC+H VC CR+ W+C VC ++ +K TG+WF
Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRI-QESNGTWRCKVCAKEIELKKATGDWF 119
Query: 121 YEERAKKF----------------PTGGKHETVGGQLLQSYQ 146
Y+++ +F P K ETVG LL Q
Sbjct: 120 YDQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQ 161
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 195 bits (496), Expect = 8e-50
Identities = 132/411 (32%), Positives = 208/411 (50%), Gaps = 26/411 (6%)
Query: 140 QLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLNQE-DPKCSTNPILKQ 198
+L++S + +S + PT P S + S P L+ + + + ++ +
Sbjct: 532 ELVRSAEDVSTV----PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQL 587
Query: 199 QNLPSSPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLE 256
SP+ T S SL S+ + + G+F N V G I+FAI Y L
Sbjct: 588 SRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELH 647
Query: 257 ICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAP 316
+ + CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++
Sbjct: 648 VFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEK 707
Query: 317 AQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSV 376
L T++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K
Sbjct: 708 QILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA 767
Query: 377 PQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFV 436
++ GE+ KL L P E G P+ G++ + V +LP+ LNSFV
Sbjct: 768 -ENRGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFV 817
Query: 437 KGCLTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMN 495
K C LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + +
Sbjct: 818 K-CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLT 874
Query: 496 DRLLGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
++ LGG R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 875 NQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 925
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/57 (40%), Positives = 34/57 (59%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEK 61
IDLS L E E+EAI++VL RD A++ EEER R L ++ + + W ++ K
Sbjct: 2 IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAK 58
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 195 bits (496), Expect = 8e-50
Identities = 132/411 (32%), Positives = 208/411 (50%), Gaps = 26/411 (6%)
Query: 140 QLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLNQE-DPKCSTNPILKQ 198
+L++S + +S + PT P S + S P L+ + + + ++ +
Sbjct: 531 ELVRSAEDVSTV----PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQL 586
Query: 199 QNLPSSPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLE 256
SP+ T S SL S+ + + G+F N V G I+FAI Y L
Sbjct: 587 SRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELH 646
Query: 257 ICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAP 316
+ + CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++
Sbjct: 647 VFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEK 706
Query: 317 AQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSV 376
L T++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K
Sbjct: 707 QILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA 766
Query: 377 PQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFV 436
++ GE+ KL L P E G P+ G++ + V +LP+ LNSFV
Sbjct: 767 -ENRGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFV 816
Query: 437 KGCLTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMN 495
K C LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + +
Sbjct: 817 K-CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLT 873
Query: 496 DRLLGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
++ LGG R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 874 NQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 924
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/57 (40%), Positives = 34/57 (59%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEK 61
IDLS L E E+EAI++VL RD A++ EEER R L ++ + + W ++ K
Sbjct: 2 IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAK 58
>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
Length = 1256
Score = 195 bits (496), Expect = 8e-50
Identities = 132/411 (32%), Positives = 208/411 (50%), Gaps = 26/411 (6%)
Query: 140 QLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKPLNQE-DPKCSTNPILKQ 198
+L++S + +S + PT P S + S P L+ + + + ++ +
Sbjct: 853 ELVRSAEDVSTV----PTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQL 908
Query: 199 QNLPSSPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLE 256
SP+ T S SL S+ + + G+F N V G I+FAI Y L
Sbjct: 909 SRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELH 968
Query: 257 ICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAP 316
+ + CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++
Sbjct: 969 VFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEK 1028
Query: 317 AQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSV 376
L T++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K
Sbjct: 1029 QILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA 1088
Query: 377 PQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFV 436
++ GE+ KL L P E G P+ G++ + V +LP+ LNSFV
Sbjct: 1089 -ENRGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFV 1138
Query: 437 KGCLTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMN 495
K C LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + +
Sbjct: 1139 K-CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLT 1195
Query: 496 DRLLGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
++ LGG R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 1196 NQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 1246
>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
Length = 376
Score = 195 bits (495), Expect = 1e-49
Identities = 122/346 (35%), Positives = 184/346 (53%), Gaps = 21/346 (6%)
Query: 204 SPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLEICIKA 261
SP+ T S SL S+ + + G+F N V G I+FAI Y L + +
Sbjct: 34 SPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQ 93
Query: 262 CKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVT 321
CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++ L T
Sbjct: 94 CKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKT 153
Query: 322 RQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNG 381
++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K ++ G
Sbjct: 154 QKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRG 212
Query: 382 ELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLT 441
E+ KL L P E G P+ G++ + V +LP+ LNSFVK C
Sbjct: 213 EM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTI 262
Query: 442 LPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLG 500
LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + + ++ LG
Sbjct: 263 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLG 320
Query: 501 GTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
G R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 321 GLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 366
>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
Length = 365
Score = 195 bits (495), Expect = 1e-49
Identities = 122/346 (35%), Positives = 184/346 (53%), Gaps = 21/346 (6%)
Query: 204 SPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLEICIKA 261
SP+ T S SL S+ + + G+F N V G I+FAI Y L + +
Sbjct: 23 SPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQ 82
Query: 262 CKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVT 321
CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++ L T
Sbjct: 83 CKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKT 142
Query: 322 RQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNG 381
++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K ++ G
Sbjct: 143 QKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRG 201
Query: 382 ELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLT 441
E+ KL L P E G P+ G++ + V +LP+ LNSFVK C
Sbjct: 202 EM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTI 251
Query: 442 LPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLG 500
LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + + ++ LG
Sbjct: 252 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLG 309
Query: 501 GTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
G R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 310 GLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 355
>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
Length = 376
Score = 195 bits (495), Expect = 1e-49
Identities = 122/346 (35%), Positives = 184/346 (53%), Gaps = 21/346 (6%)
Query: 204 SPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLEICIKA 261
SP+ T S SL S+ + + G+F N V G I+FAI Y L + +
Sbjct: 34 SPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQ 93
Query: 262 CKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVT 321
CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++ L T
Sbjct: 94 CKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKT 153
Query: 322 RQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNG 381
++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K ++ G
Sbjct: 154 QKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRG 212
Query: 382 ELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLT 441
E+ KL L P E G P+ G++ + V +LP+ LNSFVK C
Sbjct: 213 EM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTI 262
Query: 442 LPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLG 500
LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + + ++ LG
Sbjct: 263 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLG 320
Query: 501 GTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
G R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 321 GLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 366
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 195 bits (495), Expect = 1e-49
Identities = 122/346 (35%), Positives = 184/346 (53%), Gaps = 21/346 (6%)
Query: 204 SPAPSTIFSGGFRHGSLISIDSTCTEM--GNFDNANVTGEIEFAIHYCFKTHSLEICIKA 261
SP+ T S SL S+ + + G+F N V G I+FAI Y L + +
Sbjct: 930 SPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQ 989
Query: 262 CKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVT 321
CK+LA + KK++ +PYVK YLLPD+ GK+KT V + T++P + E L+Y++ L T
Sbjct: 990 CKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKT 1049
Query: 322 RQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNG 381
++L +S+WH T R FLGEV + L TWD+++ + RW+PL+ K ++ G
Sbjct: 1050 QKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRG 1108
Query: 382 ELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLT 441
E+ KL L P E G P+ G++ + V +LP+ LNSFVK C
Sbjct: 1109 EM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTI 1158
Query: 442 LPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLG 500
LPD +K R K+ + K P + H+ V+ G P L ++ +ELTVWD + + ++ LG
Sbjct: 1159 LPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLG 1216
Query: 501 GTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
G R+G S G D+ S W+K+++SPN W + TL L
Sbjct: 1217 GLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 1262
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 194 bits (494), Expect = 1e-49
Identities = 129/377 (34%), Positives = 192/377 (50%), Gaps = 30/377 (7%)
Query: 177 PDILKPLNQEDPKCST------NPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEM 230
PD N+ P+ ST NP L F GS++S+ S
Sbjct: 542 PDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYS----- 596
Query: 231 GNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQ 290
G+F N V G I+FAI Y L + + CK+LA + KK++ +PYVK YLLPD+
Sbjct: 597 GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKM 656
Query: 291 GKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATW 350
GK+KT V + T++P + E L+Y++ L T++L +S+WH T R FLGEV + L TW
Sbjct: 657 GKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETW 716
Query: 351 DFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSL 410
D+++ + RW+PL+ K ++ GE+ KL L P E G P+
Sbjct: 717 DWDNKQNKQLRWYPLKRKTAPVALEA-ENRGEM----KLALQYVP----EPVPGKKLPTT 767
Query: 411 HGQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPD-QQKLRLKSPVLRKQACPQWKHSFVF 469
G++ + V +LP+ LNSFVK C LPD +K R K+ + K P + H+ V+
Sbjct: 768 -GEVHIWVKECLDLPLLRGSHLNSFVK-CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 825
Query: 470 SGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTAVGGDACSLSKLQW 524
G P L ++ +ELTVWD + + ++ LGG R+G S G D+ S W
Sbjct: 826 DGFRPEDLMEACVELTVWDH--YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALW 883
Query: 525 QKVLSSPNLWTDMTLVL 541
+K+++SPN W + TL L
Sbjct: 884 EKMVNSPNTWIEATLPL 900
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/57 (40%), Positives = 34/57 (59%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEK 61
IDLS L E E+EAI++VL RD A++ EEER R L ++ + + W ++ K
Sbjct: 2 IDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAK 58
>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
Length = 336
Score = 194 bits (492), Expect = 2e-49
Identities = 119/330 (36%), Positives = 180/330 (54%), Gaps = 24/330 (7%)
Query: 218 GSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNP 277
GS++S+ S G+F N V G I+FAI Y L + + CK+LA + KK++ +P
Sbjct: 15 GSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDP 69
Query: 278 YVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARR 337
YVK YLLPD+ GK+KT V + T++P + E L+Y++ L T++L +S+WH T R
Sbjct: 70 YVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRN 129
Query: 338 VFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRK 397
FLGEV + L TWD+++ + RW+PL+ K ++ GE+ KL L P
Sbjct: 130 SFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-ENRGEM----KLALQYVP-- 182
Query: 398 LQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPD-QQKLRLKSPVLR 456
E G P+ G++ + V +LP+ LNSFVK C LPD +K R K+ +
Sbjct: 183 --EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-CTILPDTSRKSRQKTRAVG 238
Query: 457 KQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTA 511
K P + H+ V+ G P L ++ +ELTVWD + + ++ LGG R+G S G
Sbjct: 239 KTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQFLGGLRIGFGTGKSYGTEV 296
Query: 512 VGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
D+ S W+K+++SPN W + TL L
Sbjct: 297 DWMDSTSEEVALWEKMVNSPNTWIEATLPL 326
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 181 bits (458), Expect = 2e-45
Identities = 166/545 (30%), Positives = 246/545 (45%), Gaps = 42/545 (7%)
Query: 5 IDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCA 64
+DLS L E E+EAI VL RD ++ EE R KL+ + DW + +
Sbjct: 32 LDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLRASVADPGQLKILTGDWFQEARSQR 91
Query: 65 RCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEER 124
G L R ++ R S R A K + + I +ER
Sbjct: 92 HHNAHFGSDLVRASMRRKKSTRGDQAPGHDREAEAAVKEKEEGPEPRLTIDEAP---QER 148
Query: 125 AKKFPTGGKHETVGGQLL--QSYQKLSKISVVPPTPPPVSESQCSRSPGRKVSAPDILKP 182
++ E Q Q Q++ P P Q R + A +
Sbjct: 149 LRETEASDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAASQILE 208
Query: 183 LNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEI 242
+E P +P L + L SS + S++ S GS +S+ G+ + V G +
Sbjct: 209 NGEEAP--GPDPSLDRM-LSSSSSVSSLNSSTLS-GSQMSLS------GDAEAVQVRGSV 258
Query: 243 EFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTV 302
FA+HY L + + C+ LA ++++ +PYVK+YLLPD+ Q KRKT V++ +
Sbjct: 259 HFALHYEPGAAELRVHVIQCQGLAAA--RRRRSDPYVKSYLLPDK--QSKRKTAVKKRNL 314
Query: 303 DPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRW 362
+P F ETL+Y V A+L R L +SVWH +L R +FLGEV +PL TWD+ T W
Sbjct: 315 NPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPT----W 370
Query: 363 HPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAK 422
PL+ + D +P S G L + K V EG P G+L V A+
Sbjct: 371 LPLQPRVPPSPDDLP-SRGLLALSLKYV--------PAGSEGAGLPP-SGELHFWVKEAR 420
Query: 423 NLPVRPDGTLNSFVKGCLTLP-DQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSS 481
+L G+L+++V+ C LP D Q R ++ V+R+ P + H+ V+ G PA LRQ+
Sbjct: 421 DLLPLRAGSLDTYVQ-CFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQAC 479
Query: 482 LELTVWDQALFGMNDRLLGGTRLGSKGDTAVG-----GDACSLSKLQWQKVLSSPNLWTD 536
EL++WD + +R LGGTRL ++ G D+ K WQ +L P W D
Sbjct: 480 AELSLWDHG--ALANRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALLEQPCEWVD 537
Query: 537 MTLVL 541
L L
Sbjct: 538 GLLPL 542
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 81.3 bits (199), Expect = 2e-15
Identities = 72/280 (25%), Positives = 123/280 (43%), Gaps = 26/280 (9%)
Query: 234 DNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKR 293
D+ G ++F++ Y + ++L I K L + +PYVK +LLP S K
Sbjct: 122 DDCTALGTLDFSLLYDQENNALHCTITKAKGLK-PMDHNGLADPYVKLHLLPGASKANKL 180
Query: 294 KTGVQRNTVDPTFQETLKYQ-VAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDF 352
+T RNT++PT+ ETL Y + ++ + L++SV F+GE +PL
Sbjct: 181 RTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLK--KL 238
Query: 353 EDSTTQSFR-WHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLH 411
+ + T++F + +K ED + G + + K
Sbjct: 239 KPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKY-----------------SSQKQ 281
Query: 412 GQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSG 471
G L +V A + +G + +VK L +K + K+ V +K P++ F +
Sbjct: 282 GLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE- 340
Query: 472 VTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG--SKGD 509
+ L + SLE+TVWD + ND +GG LG +KG+
Sbjct: 341 IKHGDLAKKSLEVTVWDYDIGKSND-FIGGVVLGIHAKGE 379
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 80.5 bits (197), Expect = 4e-15
Identities = 82/294 (27%), Positives = 139/294 (47%), Gaps = 40/294 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+I F++ Y ++T +L + I +L ++ +PYVK YLLPDR K +T V R
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLP-AKDFCGSSDPYVKIYLLPDRKC--KLQTRVHR 202
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++PTF E + V +L R+L +SV+ +R +GEVI+ ++ D + ++
Sbjct: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRET 261
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W K +Y S GE+ + + LP+ G+L L V+
Sbjct: 262 SIW-----KDIQYATSESVDLGEI-MFSLCYLPTA-----------------GRLTLTVI 298
Query: 420 GAKNLPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC-PQWKHSFVFSGVTPAQL 477
+NL G + +VK L L D ++L+ K ++K P + + +F + P +
Sbjct: 299 KCRNLKAMDITGYSDPYVKVSL-LCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENM 356
Query: 478 RQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
Q SL ++V D G N+ ++G R+G TA G L + W ++L+ P
Sbjct: 357 DQVSLLISVMDYDRVGHNE-IIGVCRVGI---TAEG-----LGRDHWNEMLAYP 401
>gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens]
Length = 859
Score = 79.7 bits (195), Expect = 6e-15
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 7/136 (5%)
Query: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAK----NTDW 56
M +++DLS L + E E +LQV+ RD ++ EEER +LK Q L +G+K +
Sbjct: 1 MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSELK---QKLDEEGSKCSILSKHQ 57
Query: 57 EHKEKCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKT 116
+ E CC RC FL++ C C VC C + + AW C VC + R ++ ++
Sbjct: 58 QFVEHCCMRCCSPFTFLVNTKRQCGDCKFNVCKSCCSYQKHEKAWVCCVCQQARLLRAQS 117
Query: 117 GEWFYEERAKKFPTGG 132
EWFY +F G
Sbjct: 118 LEWFYNNVKSRFKRFG 133
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 79.7 bits (195), Expect = 6e-15
Identities = 72/293 (24%), Positives = 131/293 (44%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+++F++ Y F+ + L + + L + +PYVK +LLPD+ K +T V R
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELP-ALDMGGTSDPYVKVFLLPDKKK--KYETKVHR 197
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F ET ++V +L + L ++++ ++ +GEV +P+ T D +
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L+ EK E P+ G++ + V + G+L + +L
Sbjct: 257 --WRDLQG-GEKEE---PEKLGDICTSLRYVPTA------------------GKLTVCIL 292
Query: 420 GAKNLPVRPDGTLNS-FVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLR 478
AKNL G L+ +VK L ++ + K+ V +K P + SF F + Q++
Sbjct: 293 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQ 351
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ + +TV D G N+ + G VG +A W +L++P
Sbjct: 352 KVQVVVTVLDYDKLGKNEAI---------GKIFVGSNATGTELRHWSDMLANP 395
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 10/149 (6%)
Query: 231 GNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQ 290
G + G+I ++ Y L +CI KNL + +PYVK +L+ +
Sbjct: 263 GEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRL 321
Query: 291 GKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVII----- 345
K+KT V++ T++P F E+ +++ Q+ Q+ V+V L + +G++ +
Sbjct: 322 KKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNAT 381
Query: 346 --PLATWD--FEDSTTQSFRWHPLRAKAE 370
L W + +WH L+ + E
Sbjct: 382 GTELRHWSDMLANPRRPIAQWHSLKPEEE 410
Score = 33.9 bits (76), Expect = 0.39
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 395 PRKLQEAQEGTDQPSLHGQLCLVVLGAKNLP-VRPDGTLNSFVKGCLTLPDQQKLRLKSP 453
P L + Q D QL + VL A LP + GT + +VK L LPD++K + ++
Sbjct: 137 PENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFL-LPDKKK-KYETK 194
Query: 454 VLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMND 496
V RK P + +F F V +L +L + ++D F +D
Sbjct: 195 VHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHD 236
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 79.7 bits (195), Expect = 6e-15
Identities = 72/293 (24%), Positives = 131/293 (44%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+++F++ Y F+ + L + + L + +PYVK +LLPD+ K +T V R
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELP-ALDMGGTSDPYVKVFLLPDKKK--KYETKVHR 197
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F ET ++V +L + L ++++ ++ +GEV +P+ T D +
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L+ EK E P+ G++ + V + G+L + +L
Sbjct: 257 --WRDLQG-GEKEE---PEKLGDICTSLRYVPTA------------------GKLTVCIL 292
Query: 420 GAKNLPVRPDGTLNS-FVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLR 478
AKNL G L+ +VK L ++ + K+ V +K P + SF F + Q++
Sbjct: 293 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQ 351
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ + +TV D G N+ + G VG +A W +L++P
Sbjct: 352 KVQVVVTVLDYDKLGKNEAI---------GKIFVGSNATGTELRHWSDMLANP 395
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 10/149 (6%)
Query: 231 GNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQ 290
G + G+I ++ Y L +CI KNL + +PYVK +L+ +
Sbjct: 263 GEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRL 321
Query: 291 GKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVII----- 345
K+KT V++ T++P F E+ +++ Q+ Q+ V+V L + +G++ +
Sbjct: 322 KKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNAT 381
Query: 346 --PLATWD--FEDSTTQSFRWHPLRAKAE 370
L W + +WH L+ + E
Sbjct: 382 GTELRHWSDMLANPRRPIAQWHSLKPEEE 410
Score = 33.9 bits (76), Expect = 0.39
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 395 PRKLQEAQEGTDQPSLHGQLCLVVLGAKNLP-VRPDGTLNSFVKGCLTLPDQQKLRLKSP 453
P L + Q D QL + VL A LP + GT + +VK L LPD++K + ++
Sbjct: 137 PENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFL-LPDKKK-KYETK 194
Query: 454 VLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMND 496
V RK P + +F F V +L +L + ++D F +D
Sbjct: 195 VHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHD 236
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 79.3 bits (194), Expect = 8e-15
Identities = 74/293 (25%), Positives = 131/293 (44%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G +++++ Y F++ L + I LA + +PYV+ YLLPD+ + + +T V R
Sbjct: 110 GRLQYSLDYDFQSGQLLVGILQAMGLA-ALDLGGSSDPYVRVYLLPDK--RRRYETKVHR 166
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F ET ++V +L R L ++V+ +R +GEV +P+++ D
Sbjct: 167 QTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQ-- 224
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L+A + ++ + G++ + V + G+L ++VL
Sbjct: 225 -AWRELQAAPREEQEKL----GDICFSLRYVPTA------------------GKLTVIVL 261
Query: 420 GAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC-PQWKHSFVFSGVTPAQLR 478
AKNL G L+ L +K+R K ++K P + +F F V Q++
Sbjct: 262 EAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQ 320
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ +ELTV D G N+ + G AVG A W +L++P
Sbjct: 321 KVQVELTVLDYDKLGKNEAI---------GRVAVGAAAGGAGLRHWADMLANP 364
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 78.2 bits (191), Expect = 2e-14
Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 75/415 (18%)
Query: 146 QKLSKISVVPPTPPPVSESQCSR-SPG--------------------RKVSAP------- 177
Q+ S+ + PPTP P S + S SP R+V+ P
Sbjct: 109 QENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHN 168
Query: 178 DILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNAN 237
I + LN +P + + KQ+ L G L S + G N+
Sbjct: 169 SIRRQLNLSNPDFNIQQLQKQEQLTGI---------GRIKPELYKQRSLDNDDGRRSNSK 219
Query: 238 VTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGV 297
G++ F + Y L + I NL ++ +PYVK YLLPDR + K +T V
Sbjct: 220 ACGKLNFILKYDCDLEQLIVKIHKAVNLP-AKDFSGTSDPYVKIYLLPDRKT--KHQTKV 276
Query: 298 QRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTT 357
R T++P F E + V L R+L SV+ +R +G+V++ D D
Sbjct: 277 HRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD-HFLDLADFPR 335
Query: 358 QSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLV 417
+ W K +Y + GEL + + LP+ G+L +
Sbjct: 336 ECILW-----KDIEYVTNDNVDLGEL-MFSLCYLPTA-----------------GRLTIT 372
Query: 418 VLGAKNLPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQ 476
++ A+NL G + +VK L ++ + K+ R P + + VF V P
Sbjct: 373 IIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFD-VPPEN 431
Query: 477 LRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ Q L + V D G N+ + G VG +A L + W ++LS P
Sbjct: 432 IDQIHLSIAVMDYDRVGHNEII---------GVCQVGNEAERLGRDHWSEMLSYP 477
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 77.8 bits (190), Expect = 2e-14
Identities = 76/309 (24%), Positives = 135/309 (43%), Gaps = 41/309 (13%)
Query: 222 SIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKT 281
S+DS E ++ + G++ F + Y ++ L + I +L ++ +PYVK
Sbjct: 218 SVDS---EGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLP-AKDFTGTSDPYVKM 273
Query: 282 YLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLG 341
YLLPDR K +T V R T++P F ET ++ VA QL R+L SV+ +R +G
Sbjct: 274 YLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIG 331
Query: 342 EVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEA 401
EVI+ ++ D + ++ W + + D GE+ + + LP+
Sbjct: 332 EVILD-NLFEVSDLSREATVWKDIHCATTESIDL-----GEI-MFSLCYLPTA------- 377
Query: 402 QEGTDQPSLHGQLCLVVLGAKNLPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC 460
G++ L V+ +NL G+ + +VK L ++ + K+ +
Sbjct: 378 ----------GRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLN 427
Query: 461 PQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLS 520
P + + +F + P + Q SL + V D G N+ + G G DA L
Sbjct: 428 PVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVI---------GVCRTGLDAEGLG 477
Query: 521 KLQWQKVLS 529
+ W ++L+
Sbjct: 478 RDHWNEMLA 486
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 77.4 bits (189), Expect = 3e-14
Identities = 72/293 (24%), Positives = 132/293 (45%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G++++++ Y F+ + L + I L + +PYVK +LLPD+ K +T V R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELP-ALDMGGTSDPYVKVFLLPDKKK--KFETKVHR 200
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F E ++V ++L + L ++V+ ++ +GE +P+ T DF T +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE- 259
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L++ AEK E + G++ + V + G+L +V+L
Sbjct: 260 --WRDLQS-AEKEEQ---EKLGDICFSLRYVPTA------------------GKLTVVIL 295
Query: 420 GAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC-PQWKHSFVFSGVTPAQLR 478
AKNL G L+ + + ++L+ K ++K P + SF F V Q++
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQ 354
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ + +TV D G ND + G VG ++ W +L++P
Sbjct: 355 KVQVVVTVLDYDKIGKNDAI---------GKVFVGYNSTGAELRHWSDMLANP 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+I F++ Y L + I KNL + +PYVK +L+ + K+KT +++
Sbjct: 275 GDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKK 333
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVII-------PLATWD- 351
NT++P + E+ ++V Q+ Q+ V+V + + +G+V + L W
Sbjct: 334 NTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSD 393
Query: 352 -FEDSTTQSFRWHPLRAKAE 370
+ +WH L+ + E
Sbjct: 394 MLANPRRPIAQWHTLQVEEE 413
Score = 36.6 bits (83), Expect = 0.060
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 392 PSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLP-VRPDGTLNSFVKGCLTLPDQQKLRL 450
P KL + Q D + QL + ++ A LP + GT + +VK L LPD++K +
Sbjct: 137 PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL-LPDKKK-KF 194
Query: 451 KSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMND 496
++ V RK P + F F V ++L +L + V+D F +D
Sbjct: 195 ETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHD 239
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 77.4 bits (189), Expect = 3e-14
Identities = 72/293 (24%), Positives = 132/293 (45%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G++++++ Y F+ + L + I L + +PYVK +LLPD+ K +T V R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELP-ALDMGGTSDPYVKVFLLPDKKK--KFETKVHR 200
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F E ++V ++L + L ++V+ ++ +GE +P+ T DF T +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE- 259
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L++ AEK E + G++ + V + G+L +V+L
Sbjct: 260 --WRDLQS-AEKEEQ---EKLGDICFSLRYVPTA------------------GKLTVVIL 295
Query: 420 GAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC-PQWKHSFVFSGVTPAQLR 478
AKNL G L+ + + ++L+ K ++K P + SF F V Q++
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQ 354
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ + +TV D G ND + G VG ++ W +L++P
Sbjct: 355 KVQVVVTVLDYDKIGKNDAI---------GKVFVGYNSTGAELRHWSDMLANP 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+I F++ Y L + I KNL + +PYVK +L+ + K+KT +++
Sbjct: 275 GDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKK 333
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVII-------PLATWD- 351
NT++P + E+ ++V Q+ Q+ V+V + + +G+V + L W
Sbjct: 334 NTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSD 393
Query: 352 -FEDSTTQSFRWHPLRAKAE 370
+ +WH L+ + E
Sbjct: 394 MLANPRRPIAQWHTLQVEEE 413
Score = 36.6 bits (83), Expect = 0.060
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 392 PSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLP-VRPDGTLNSFVKGCLTLPDQQKLRL 450
P KL + Q D + QL + ++ A LP + GT + +VK L LPD++K +
Sbjct: 137 PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL-LPDKKK-KF 194
Query: 451 KSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMND 496
++ V RK P + F F V ++L +L + V+D F +D
Sbjct: 195 ETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHD 239
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 77.4 bits (189), Expect = 3e-14
Identities = 72/293 (24%), Positives = 132/293 (45%), Gaps = 39/293 (13%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G++++++ Y F+ + L + I L + +PYVK +LLPD+ K +T V R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELP-ALDMGGTSDPYVKVFLLPDKKK--KFETKVHR 200
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQS 359
T++P F E ++V ++L + L ++V+ ++ +GE +P+ T DF T +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE- 259
Query: 360 FRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVL 419
W L++ AEK E + G++ + V + G+L +V+L
Sbjct: 260 --WRDLQS-AEKEEQ---EKLGDICFSLRYVPTA------------------GKLTVVIL 295
Query: 420 GAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQAC-PQWKHSFVFSGVTPAQLR 478
AKNL G L+ + + ++L+ K ++K P + SF F V Q++
Sbjct: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQ 354
Query: 479 QSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ + +TV D G ND + G VG ++ W +L++P
Sbjct: 355 KVQVVVTVLDYDKIGKNDAI---------GKVFVGYNSTGAELRHWSDMLANP 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 240 GEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQR 299
G+I F++ Y L + I KNL + +PYVK +L+ + K+KT +++
Sbjct: 275 GDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKK 333
Query: 300 NTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVII-------PLATWD- 351
NT++P + E+ ++V Q+ Q+ V+V + + +G+V + L W
Sbjct: 334 NTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSD 393
Query: 352 -FEDSTTQSFRWHPLRAKAE 370
+ +WH L+ + E
Sbjct: 394 MLANPRRPIAQWHTLQVEEE 413
Score = 36.6 bits (83), Expect = 0.060
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 392 PSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLP-VRPDGTLNSFVKGCLTLPDQQKLRL 450
P KL + Q D + QL + ++ A LP + GT + +VK L LPD++K +
Sbjct: 137 PKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL-LPDKKK-KF 194
Query: 451 KSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMND 496
++ V RK P + F F V ++L +L + V+D F +D
Sbjct: 195 ETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHD 239
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 75.5 bits (184), Expect = 1e-13
Identities = 93/409 (22%), Positives = 162/409 (39%), Gaps = 60/409 (14%)
Query: 129 PTGGKHETVGGQLLQSYQKLSKISVV---PPTPPPVSESQCSRSP--GRKVSAPDILKPL 183
P+GG G QS+Q+++ ++ P P P+++ + P + P + PL
Sbjct: 203 PSGG-----GLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLPL 257
Query: 184 NQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIE 243
+ K +K + L P SGG + C G I
Sbjct: 258 PGGEEKAKLIGQIKPE-LYQGTGPGGRRSGGGPGSGEAGTGAPC------------GRIS 304
Query: 244 FAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVD 303
FA+ Y + + L + I +L ++ +PYVK YLLPDR K +T V R T++
Sbjct: 305 FALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRKTLN 361
Query: 304 PTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWH 363
P F ET ++ V A+L R+L SV+ +R +G+V++ + + W
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWR 420
Query: 364 PLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKN 423
+ + D GEL + LP+ G+L + ++ A N
Sbjct: 421 DIVEGGSEKADL-----GELNF-SLCYLPTA-----------------GRLTVTIIKASN 457
Query: 424 LPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSL 482
L G + +VK L ++ + K+ + + P + + VF V P + L
Sbjct: 458 LKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPESVENVGL 516
Query: 483 ELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ V D G N+ ++G R+G G + W ++L++P
Sbjct: 517 SIAVVDYDCIGHNE-VIGVCRVGPDAADPHGRE-------HWAEMLANP 557
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 75.5 bits (184), Expect = 1e-13
Identities = 93/409 (22%), Positives = 162/409 (39%), Gaps = 60/409 (14%)
Query: 129 PTGGKHETVGGQLLQSYQKLSKISVV---PPTPPPVSESQCSRSP--GRKVSAPDILKPL 183
P+GG G QS+Q+++ ++ P P P+++ + P + P + PL
Sbjct: 203 PSGG-----GLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLPL 257
Query: 184 NQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIE 243
+ K +K + L P SGG + C G I
Sbjct: 258 PGGEEKAKLIGQIKPE-LYQGTGPGGRRSGGGPGSGEAGTGAPC------------GRIS 304
Query: 244 FAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVD 303
FA+ Y + + L + I +L ++ +PYVK YLLPDR K +T V R T++
Sbjct: 305 FALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRKTLN 361
Query: 304 PTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWH 363
P F ET ++ V A+L R+L SV+ +R +G+V++ + + W
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWR 420
Query: 364 PLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKN 423
+ + D GEL + LP+ G+L + ++ A N
Sbjct: 421 DIVEGGSEKADL-----GELNF-SLCYLPTA-----------------GRLTVTIIKASN 457
Query: 424 LPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSL 482
L G + +VK L ++ + K+ + + P + + VF V P + L
Sbjct: 458 LKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPESVENVGL 516
Query: 483 ELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ V D G N+ ++G R+G G + W ++L++P
Sbjct: 517 SIAVVDYDCIGHNE-VIGVCRVGPDAADPHGRE-------HWAEMLANP 557
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 75.5 bits (184), Expect = 1e-13
Identities = 93/409 (22%), Positives = 162/409 (39%), Gaps = 60/409 (14%)
Query: 129 PTGGKHETVGGQLLQSYQKLSKISVV---PPTPPPVSESQCSRSP--GRKVSAPDILKPL 183
P+GG G QS+Q+++ ++ P P P+++ + P + P + PL
Sbjct: 203 PSGG-----GLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLPL 257
Query: 184 NQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIE 243
+ K +K + L P SGG + C G I
Sbjct: 258 PGGEEKAKLIGQIKPE-LYQGTGPGGRRSGGGPGSGEAGTGAPC------------GRIS 304
Query: 244 FAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVD 303
FA+ Y + + L + I +L ++ +PYVK YLLPDR K +T V R T++
Sbjct: 305 FALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK--KFQTKVHRKTLN 361
Query: 304 PTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWH 363
P F ET ++ V A+L R+L SV+ +R +G+V++ + + W
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRPLWR 420
Query: 364 PLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKN 423
+ + D GEL + LP+ G+L + ++ A N
Sbjct: 421 DIVEGGSEKADL-----GELNF-SLCYLPTA-----------------GRLTVTIIKASN 457
Query: 424 LPVRP-DGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSL 482
L G + +VK L ++ + K+ + + P + + VF V P + L
Sbjct: 458 LKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPESVENVGL 516
Query: 483 ELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSP 531
+ V D G N+ ++G R+G G + W ++L++P
Sbjct: 517 SIAVVDYDCIGHNE-VIGVCRVGPDAADPHGRE-------HWAEMLANP 557
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,178,696
Number of Sequences: 37866
Number of extensions: 1167317
Number of successful extensions: 4466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 4109
Number of HSP's gapped (non-prelim): 323
length of query: 542
length of database: 18,247,518
effective HSP length: 107
effective length of query: 435
effective length of database: 14,195,856
effective search space: 6175197360
effective search space used: 6175197360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.