Guide to the Human Genome
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Search of human proteins with 150010645

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150010645 clarin 2 [Homo sapiens]
         (232 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150010645 clarin 2 [Homo sapiens]                                  459   e-130
gi|28144908 clarin 1 isoform a [Homo sapiens]                         162   2e-40
gi|16506281 clarin 1 isoform c [Homo sapiens]                          74   8e-14
gi|22748685 clarin 3 [Homo sapiens]                                    69   3e-12
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                 33   0.16 
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                 33   0.16 
gi|218749848 family with sequence similarity 38, member A [Homo ...    33   0.27 
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                 31   0.79 
gi|209870067 R3H domain and coiled-coil containing 1 [Homo sapiens]    30   1.8  
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]            28   5.1  
gi|10863887 claudin 1 [Homo sapiens]                                   28   5.1  
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho...    28   6.7  

>gi|150010645 clarin 2 [Homo sapiens]
          Length = 232

 Score =  459 bits (1181), Expect = e-130
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60
           MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD
Sbjct: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60

Query: 61  IYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAI 120
           IYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAI
Sbjct: 61  IYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAI 120

Query: 121 LNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVV 180
           LNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVV
Sbjct: 121 LNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVV 180

Query: 181 VEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY 232
           VEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY
Sbjct: 181 VEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY 232


>gi|28144908 clarin 1 isoform a [Homo sapiens]
          Length = 232

 Score =  162 bits (411), Expect = 2e-40
 Identities = 81/232 (34%), Positives = 131/232 (56%)

Query: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60
           MP   KK  + +A + SF+  + ++ AL  P W+   +LC+TG  LVNA+ +EL KF+G+
Sbjct: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60

Query: 61  IYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAI 120
           + YGLF G  VRQCGLG R  +F+ FP L+K +   +HV ++L   + + L +V   F +
Sbjct: 61  MQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFM 120

Query: 121 LNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVV 180
            N    P+  + GP G+ L + ++G    L +  F + VK H L+E+IAN++E  + +  
Sbjct: 121 YNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKT 180

Query: 181 VEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY 232
             E+Y  SFW+       H  N +++ ++    P  K+K  E T  A D++Y
Sbjct: 181 QSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY 232


>gi|16506281 clarin 1 isoform c [Homo sapiens]
          Length = 120

 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 34/110 (30%), Positives = 60/110 (54%)

Query: 82  QFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWN 141
           Q  +FP L+K +   +HV ++L   + + L +V   F + N    P+  + GP G+ L +
Sbjct: 6   QQPVFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLS 65

Query: 142 VLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWI 191
            ++G    L +  F + VK H L+E+IAN++E  + +    E+Y  SFW+
Sbjct: 66  FISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWL 115


>gi|22748685 clarin 3 [Homo sapiens]
          Length = 226

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 12/212 (5%)

Query: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60
           MP   K   +  +   S  SFI+I   L    W++  I  +      +A++  +      
Sbjct: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRD-----SASNGSIF----- 50

Query: 61  IYYGLFRGCKVRQC--GLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGF 118
           I YGLFRG    +   GL   + +F +   L       LH + +L L L+L  +L+S GF
Sbjct: 51  ITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGF 110

Query: 119 AILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQF 178
              N I  PY+   GP G+  WN L    V + +  FVA  + + L+E +          
Sbjct: 111 TFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTS 170

Query: 179 VVVEEQYEESFWICVASASAHAANLVVVAISQ 210
                 Y  SFW+ +     +   + ++   Q
Sbjct: 171 KGTTHSYGYSFWLILLVILLNIVTVTIIIFYQ 202


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 22/156 (14%)

Query: 5   FKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYG 64
           F+ A   +  LLSF  +IL I+   +PHW +           +N    E+  +      G
Sbjct: 5   FRTAMQSVGLLLSFLGWILSIITTYLPHWKN-----------LNLDLNEMENWT----MG 49

Query: 65  LFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMI 124
           L++ C +++  +G +   F  F  L  EL     +M L      L L +   G   L + 
Sbjct: 50  LWQTCVIQE-EVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108

Query: 125 QVP---YRAVSGPGGICLWNVLAGGVVALAIASFVA 157
           +      R +   GGI  W   A G+ AL   S+VA
Sbjct: 109 ESQRDLKRRLLILGGILSW---ASGITALVPVSWVA 141


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 22/156 (14%)

Query: 5   FKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYG 64
           F+ A   +  LLSF  +IL I+   +PHW +           +N    E+  +      G
Sbjct: 5   FRTAMQSVGLLLSFLGWILSIITTYLPHWKN-----------LNLDLNEMENWT----MG 49

Query: 65  LFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMI 124
           L++ C +++  +G +   F  F  L  EL     +M L      L L +   G   L + 
Sbjct: 50  LWQTCVIQE-EVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108

Query: 125 QVP---YRAVSGPGGICLWNVLAGGVVALAIASFVA 157
           +      R +   GGI  W   A G+ AL   S+VA
Sbjct: 109 ESQRDLKRRLLILGGILSW---ASGITALVPVSWVA 141


>gi|218749848 family with sequence similarity 38, member A [Homo
           sapiens]
          Length = 2090

 Score = 32.7 bits (73), Expect = 0.27
 Identities = 21/94 (22%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 124 IQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEE 183
           +  P++A   P G   W ++A  ++ LA         F D+  R+  F  +L +  V + 
Sbjct: 334 VATPHQATQVPEGAAKWGLVAERLLELAAG-------FSDVLSRVQVFLRRLLELHVFKL 386

Query: 184 QYEESFWICVASASAHAANLVVVAISQIPLPEIK 217
               + W+ +   S     LVV+    +P P  +
Sbjct: 387 VALYTVWVALKEVSVMNLLLVVLWAFALPYPRFR 420


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 31.2 bits (69), Expect = 0.79
 Identities = 40/156 (25%), Positives = 63/156 (40%), Gaps = 22/156 (14%)

Query: 5   FKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYG 64
           F+ A   +  LLS   +IL I+   +PHW +           +N    E+  +      G
Sbjct: 5   FRTAMQSVGLLLSLLGWILSIITTYLPHWKN-----------LNLDLNEMENWT----MG 49

Query: 65  LFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMI 124
           L++ C +++  +G +   F  F  L  EL     +M L      L L +   G   L + 
Sbjct: 50  LWQTCVIQE-EVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108

Query: 125 QVP---YRAVSGPGGICLWNVLAGGVVALAIASFVA 157
           +      R +   GGI  W   A G+ AL   S+VA
Sbjct: 109 ESQRDLKRRLLILGGILSW---ASGITALVPVSWVA 141


>gi|209870067 R3H domain and coiled-coil containing 1 [Homo sapiens]
          Length = 253

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/46 (34%), Positives = 25/46 (54%)

Query: 152 IASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASAS 197
           I  F  A+K  DL    + FQEK F+   V++ +    + C+ASA+
Sbjct: 135 IYDFEPALKTEDLLATFSEFQEKGFRIQWVDDTHALGIFPCLASAA 180


>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
          Length = 852

 Score = 28.5 bits (62), Expect = 5.1
 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 99  VMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASF 155
           +++LLLL LAL L L ++G  + +      +A  GP  +  + ++  G+V L++  F
Sbjct: 570 LLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGP--LACFGLVCLGLVCLSVLLF 624


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score = 28.5 bits (62), Expect = 5.1
 Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 19/117 (16%)

Query: 12  LASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKV 71
           L  +L+F  +I  IV+  +P W   +I    G ++V A           +Y GL+  C  
Sbjct: 9   LGFILAFLGWIGAIVSTALPQW---RIYSYAGDNIVTAQ---------AMYEGLWMSCVS 56

Query: 72  RQCGLGGRQSQFTIFPHLV---KELNAGLHVMILLLLFLALALALVSMGFAILNMIQ 125
           +  G    Q Q  +F  L+     L A   +M++ +L   +A+ + ++G   +  ++
Sbjct: 57  QSTG----QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLE 109


>gi|5729756 voltage-dependent calcium channel gamma-3 subunit
          [Homo sapiens]
          Length = 315

 Score = 28.1 bits (61), Expect = 6.7
 Identities = 15/53 (28%), Positives = 30/53 (56%), Gaps = 2/53 (3%)

Query: 17 SFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGC 69
          +F++F L+ +A+   +WL  + +C+T     N T R+  + +   + GL+R C
Sbjct: 17 AFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVM--THSGLWRTC 67


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,591,510
Number of Sequences: 37866
Number of extensions: 274415
Number of successful extensions: 979
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 970
Number of HSP's gapped (non-prelim): 13
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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