Guide to the Human Genome
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Search of human proteins with 148539554

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo
sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo sa...   852   0.0  
gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]               338   7e-93
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]       40   0.003
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]       40   0.003
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]            31   2.4  
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]            31   2.4  
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]            31   2.4  
gi|4504477 4-hydroxyphenylpyruvate dioxygenase [Homo sapiens]          30   5.4  
gi|19923642 Hermansky-Pudlak syndrome 3 protein [Homo sapiens]         29   7.0  
gi|239750429 PREDICTED: hypothetical protein XP_002347393 [Homo ...    29   9.1  
gi|239744731 PREDICTED: hypothetical protein XP_002343256 [Homo ...    29   9.1  

>gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo
           sapiens]
          Length = 420

 Score =  852 bits (2200), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA 60
           MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA
Sbjct: 1   MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA 60

Query: 61  NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL 120
           NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL
Sbjct: 61  NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL 120

Query: 121 PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF 180
           PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF
Sbjct: 121 PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF 180

Query: 181 ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP 240
           ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP
Sbjct: 181 ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP 240

Query: 241 DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK 300
           DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK
Sbjct: 241 DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK 300

Query: 301 ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH 360
           ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH
Sbjct: 301 ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH 360

Query: 361 ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG 420
           ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG
Sbjct: 361 ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG 420


>gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]
          Length = 403

 Score =  338 bits (866), Expect = 7e-93
 Identities = 172/390 (44%), Positives = 248/390 (63%), Gaps = 5/390 (1%)

Query: 30  ESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQAHVDKMPLLSCQFLKG 89
           + YHI EE GF LP+  + LPD Y  WM IA  LP LI++ QL+  V+K+ +LS   L  
Sbjct: 13  KEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTD 72

Query: 90  HREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLT 149
           H+ QRLA LVL  +TM YVW +G     +VLPRN+A+P+ ++S+ L LPPILV++D VL 
Sbjct: 73  HKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLA 132

Query: 150 NWTKKDPDGFLEIGNLETIISFPGGESLHGFILVTALVEKEAVPGIKALVQATNAILQPN 209
           NW KKDP+  L   N++ + SF  G+   GF LV+ LVE  A   IK +     A+    
Sbjct: 133 NWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQE 192

Query: 210 QEALLQALQRLRLSIQDITKTLGQMHDYVDPDIFYAGIRIFLSGWKDNPAMPAGLMYEGV 269
           ++ LL+AL  +   ++   +   Q+HD+V+P  F++ +RI+LSGWK NP +  GL+YEG 
Sbjct: 193 RDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGF 252

Query: 270 SQEPLKYSGGSAAQSTVLHAFDEFLGIRHSKESG---DFLYRMRDYMPPSHKAFIEDIHS 326
            ++P +++GGSA QS+V   FD  LGI+ +   G    FL  MR YMPP+H+ F+  + S
Sbjct: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312

Query: 327 APSLRDYILSSGQDHLLTAYNQCVQALAELRSYHITMVTKYLITAAAKAKHGKPNHLPGP 386
            PS+R+++LS G   L  AY+ CV+AL  LRSYH+ +VTKY++  A  ++  K N     
Sbjct: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPA--SQQPKENKTSED 370

Query: 387 PQALKDRGTGGTAVMSFLKSVRDKTLESIL 416
           P  L+ +GTGGT +M+FLK+VR  T +S+L
Sbjct: 371 PSKLEAKGTGGTDLMNFLKTVRSTTEKSLL 400


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 18/64 (28%), Positives = 36/64 (56%)

Query: 183 VTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDPDI 242
           + A VE+ AV G++ L  A   ++Q   E + + LQ  ++++QD  K L + ++ ++ D+
Sbjct: 594 IRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDL 653

Query: 243 FYAG 246
              G
Sbjct: 654 TLLG 657


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 18/64 (28%), Positives = 36/64 (56%)

Query: 183 VTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDPDI 242
           + A VE+ AV G++ L  A   ++Q   E + + LQ  ++++QD  K L + ++ ++ D+
Sbjct: 594 IRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDL 653

Query: 243 FYAG 246
              G
Sbjct: 654 TLLG 657


>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 113 EAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETI 168
           EA+P  VL    + PF E S  + L  +     + + +W KK P GF+E+   + +
Sbjct: 274 EAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIP-GFVELSLFDQV 328


>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 113 EAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETI 168
           EA+P  VL    + PF E S  + L  +     + + +W KK P GF+E+   + +
Sbjct: 274 EAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIP-GFVELSLFDQV 328


>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
          Length = 530

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 113 EAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETI 168
           EA+P  VL    + PF E S  + L  +     + + +W KK P GF+E+   + +
Sbjct: 274 EAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIP-GFVELSLFDQV 328


>gi|4504477 4-hydroxyphenylpyruvate dioxygenase [Homo sapiens]
          Length = 393

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 244 YAGIR-IFLSGWKDNPAMPAGLMYEGVS----QEPLKYSGGSAAQSTVLHAFDEFLGIRH 298
           Y+ +R I ++ ++++  MP      G      QE + Y+GG+  Q   L   D    IRH
Sbjct: 221 YSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRH 280

Query: 299 SKESG--------DFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCV 350
            +E G         +  ++R+ +  +     E+I +   L+  +    + +LL  + + V
Sbjct: 281 LRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPV 340

Query: 351 Q 351
           Q
Sbjct: 341 Q 341


>gi|19923642 Hermansky-Pudlak syndrome 3 protein [Homo sapiens]
          Length = 1004

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 11/152 (7%)

Query: 25  VPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQAHVDKMPLLSC 84
           VP  L + H+ E    LL  S+  L  + +  +E A+   +++ A       D +P L  
Sbjct: 725 VPTEL-ALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKD----EDTIPQLLV 779

Query: 85  QFLKGHREQRLAHLVLSFL----TMGYVWQEGEAQPAEVLPRNLALPFVEVSRNLGLPPI 140
            F +      L  +VL  L    T  Y+W+  + QP +  P   +   +    + GL   
Sbjct: 780 DFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYP 839

Query: 141 LVHSDLVLTNWTKKDPDGFLEIGNLETIISFP 172
            VH  +V+++ +  D +   ++  L+++I  P
Sbjct: 840 WVH--VVISSDSLADKNYTEDLSKLQSLICGP 869


>gi|239750429 PREDICTED: hypothetical protein XP_002347393 [Homo
           sapiens]
          Length = 290

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 13/36 (36%), Positives = 21/36 (58%)

Query: 382 HLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILH 417
           H+PG    ++D+G+GGTA  + +    D  L  +LH
Sbjct: 111 HVPGGISGVQDQGSGGTAGSAIVDRPVDTELLMLLH 146


>gi|239744731 PREDICTED: hypothetical protein XP_002343256 [Homo
           sapiens]
          Length = 290

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 13/36 (36%), Positives = 21/36 (58%)

Query: 382 HLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILH 417
           H+PG    ++D+G+GGTA  + +    D  L  +LH
Sbjct: 111 HVPGGISGVQDQGSGGTAGSAIVDRPVDTELLMLLH 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,918,655
Number of Sequences: 37866
Number of extensions: 758785
Number of successful extensions: 1735
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1727
Number of HSP's gapped (non-prelim): 11
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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