Guide to the Human Genome
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Name: HMGCS1 Sequence: fasta or formatted (520aa) NCBI GI: 148298677
Description:

hydroxymethylglutaryl-CoA synthase 1

Referenced in:

Cholesterol Biosynthesis
Fatty Acid Oxidation and Ketone Bodies

Other entries for this name:
alt mRNA [520aa] hydroxymethylglutaryl-CoA synthase 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         44           2
 C cysteine            1.9         10           1
 D aspartate           7.1         37           2
 E glutamate           5.4         28           2
 F phenylalanine       3.5         18           1
 G glycine             7.7         40           2
 H histidine           1.9         10           2
 I isoleucine          4.8         25           2
 K lysine              5.6         29           2
 L leucine             9.2         48           2
 M methionine          2.3         12           1
 N asparagine          5.0         26           2
 P proline             4.0         21           1
 Q glutamine           3.5         18           2
 R arginine            4.0         21           2
 S serine              7.7         40           3
 T threonine           5.6         29           2
 V valine              6.5         34           2
 W tryptophan          1.0          5           1
 Y tyrosine            4.8         25           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxymethylglutaryl-CoA synthase 1 
HMGCS1                1.000   hydroxymethylglutaryl-CoA synthase 1 
HMGCS2                0.623   hydroxymethylglutaryl-CoA synthase 2 
FAT1                  0.005   FAT tumor suppressor 1 precursor 
C6orf204              0.005   chromosome 6 open reading frame 204 isoform a [Homo...
ZBBX                  0.005   zinc finger, B-box domain containing 
C6orf204              0.005   chromosome 6 open reading frame 204 isoform b [Homo...
RPAP2                 0.004   RNA polymerase II associated protein 2 
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform a [Hom...
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform c [Homo...
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform d [Ho...
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform b [Ho...
NFAT5                 0.004   nuclear factor of activated T-cells 5 isoform a [Hom...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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