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Search of human proteins with 148233338
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148233338 catenin (cadherin-associated protein), beta 1,
88kDa [Homo sapiens]
(781 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 1551 0.0
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD... 1551 0.0
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ... 1551 0.0
gi|4504811 junction plakoglobin [Homo sapiens] 952 0.0
gi|12056468 junction plakoglobin [Homo sapiens] 952 0.0
gi|31657114 armadillo repeat containing 4 [Homo sapiens] 72 2e-12
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 67 6e-11
gi|224589129 karyopherin 7 [Homo sapiens] 54 4e-07
gi|4504897 karyopherin alpha 2 [Homo sapiens] 54 4e-07
gi|4502247 armadillo repeat protein [Homo sapiens] 54 4e-07
gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens] 50 6e-06
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 49 1e-05
gi|189011568 adenomatous polyposis coli [Homo sapiens] 49 2e-05
gi|189011566 adenomatous polyposis coli [Homo sapiens] 49 2e-05
gi|53759122 adenomatous polyposis coli [Homo sapiens] 49 2e-05
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 47 7e-05
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 47 7e-05
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 47 7e-05
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 47 7e-05
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 47 7e-05
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 47 7e-05
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens] 47 7e-05
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 47 7e-05
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 47 7e-05
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 47 7e-05
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 47 7e-05
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 47 7e-05
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens] 47 7e-05
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens] 47 9e-05
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 42 0.002
>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 1551 bits (4016), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
Query: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
Query: 781 L 781
L
Sbjct: 781 L 781
>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 1551 bits (4016), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
Query: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
Query: 781 L 781
L
Sbjct: 781 L 781
>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 1551 bits (4016), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS
Sbjct: 1 MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTS 60
Query: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT
Sbjct: 61 QVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPT 120
Query: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK
Sbjct: 121 NVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSK 180
Query: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
Sbjct: 181 KEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL 240
Query: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
Sbjct: 241 VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC 300
Query: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA
Sbjct: 301 LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEA 360
Query: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA
Sbjct: 361 GGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCA 420
Query: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM
Sbjct: 421 AGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEM 480
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL
Sbjct: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
Query: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV
Sbjct: 541 VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
Query: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
Sbjct: 601 QLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF 660
Query: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH
Sbjct: 661 RMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFH 720
Query: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD
Sbjct: 721 SGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTD 780
Query: 781 L 781
L
Sbjct: 781 L 781
>gi|4504811 junction plakoglobin [Homo sapiens]
Length = 745
Score = 952 bits (2462), Expect = 0.0
Identities = 511/749 (68%), Positives = 585/749 (78%), Gaps = 19/749 (2%)
Query: 8 MELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWE 67
ME+ ME K V+ WQQ DSGIHSGA T PS+S KG EE++ Q +
Sbjct: 1 MEVMNLMEQPIK--VTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKT 58
Query: 68 QGFSQSFTQEQVADIDGQYAMT-RAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLA 126
++Q Q D++ Q + T RA+RVR AM P E + TN+QRLA
Sbjct: 59 TTYTQGVPPSQ-GDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLA 117
Query: 127 EPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRH 186
EPSQ+LK A+V+LINYQDDAELATRA+PELTKLLNDED VVV KAA++V+QLSKKEASR
Sbjct: 118 EPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRR 177
Query: 187 AIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS 246
A+M SPQ+V+A+VRTMQNT+D++TARCT LHNLSHHREGLLAIFKSGGIPALV+ML S
Sbjct: 178 ALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSS 237
Query: 247 PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAY 306
PV+SVLFYAITTLHNLLL+QEGAKMAVRLA GLQKMV LLNK N KFLAITTDCLQ+LAY
Sbjct: 238 PVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAY 297
Query: 307 GNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQAL 366
GNQESKLIILA+GGPQALV IMR Y+YEKLLWTTSRVLKVLSVC SNKPAIVEAGGMQAL
Sbjct: 298 GNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357
Query: 367 GLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSN 426
G HLT S RLVQNCLWTLRNLSD ATKQEG+E +L LV L DD+NV+TCA G LSN
Sbjct: 358 GKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSN 417
Query: 427 LTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVR 486
LTCNN KNK +V Q G+EAL+ +LRAGD++DITEPA+CALRHLTSRH EAEMAQN+VR
Sbjct: 418 LTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVR 477
Query: 487 LHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD 546
L+YG+P +VKLL+ P+ WPL+KAT+GLIRNLALCPANHAPL+E IPRLVQLLV+AHQD
Sbjct: 478 LNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQD 537
Query: 547 TQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSP 606
QR + GTQQ + +GVRMEEIVEGCTGALHILARD NR+ I LNTIPLFVQLLYS
Sbjct: 538 AQRHVA-AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSS 596
Query: 607 IENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
+ENIQRVAAGVLCELAQDKEAA+AI+AEGA+APL ELLHSRNEG ATYAAAVLFR+SEDK
Sbjct: 597 VENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656
Query: 667 PQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQ 726
DY+KR+SVELT+SLF+ +P AW E A + I EP G D +YR +S
Sbjct: 657 NPDYRKRVSVELTNSLFKHDPAAW-EAAQSMIPI---NEPYG-DDMDATYRPMYSSDVPL 711
Query: 727 DALGMDPMMEHEMGGHHPGADYPVDGLPD 755
D L M M+ DYP+D D
Sbjct: 712 DPLEMHMDMD---------GDYPIDTYSD 731
>gi|12056468 junction plakoglobin [Homo sapiens]
Length = 745
Score = 952 bits (2462), Expect = 0.0
Identities = 511/749 (68%), Positives = 585/749 (78%), Gaps = 19/749 (2%)
Query: 8 MELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWE 67
ME+ ME K V+ WQQ DSGIHSGA T PS+S KG EE++ Q +
Sbjct: 1 MEVMNLMEQPIK--VTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKT 58
Query: 68 QGFSQSFTQEQVADIDGQYAMT-RAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLA 126
++Q Q D++ Q + T RA+RVR AM P E + TN+QRLA
Sbjct: 59 TTYTQGVPPSQ-GDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLA 117
Query: 127 EPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRH 186
EPSQ+LK A+V+LINYQDDAELATRA+PELTKLLNDED VVV KAA++V+QLSKKEASR
Sbjct: 118 EPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRR 177
Query: 187 AIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS 246
A+M SPQ+V+A+VRTMQNT+D++TARCT LHNLSHHREGLLAIFKSGGIPALV+ML S
Sbjct: 178 ALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSS 237
Query: 247 PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAY 306
PV+SVLFYAITTLHNLLL+QEGAKMAVRLA GLQKMV LLNK N KFLAITTDCLQ+LAY
Sbjct: 238 PVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAY 297
Query: 307 GNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQAL 366
GNQESKLIILA+GGPQALV IMR Y+YEKLLWTTSRVLKVLSVC SNKPAIVEAGGMQAL
Sbjct: 298 GNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQAL 357
Query: 367 GLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSN 426
G HLT S RLVQNCLWTLRNLSD ATKQEG+E +L LV L DD+NV+TCA G LSN
Sbjct: 358 GKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSN 417
Query: 427 LTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVR 486
LTCNN KNK +V Q G+EAL+ +LRAGD++DITEPA+CALRHLTSRH EAEMAQN+VR
Sbjct: 418 LTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVR 477
Query: 487 LHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD 546
L+YG+P +VKLL+ P+ WPL+KAT+GLIRNLALCPANHAPL+E IPRLVQLLV+AHQD
Sbjct: 478 LNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQD 537
Query: 547 TQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSP 606
QR + GTQQ + +GVRMEEIVEGCTGALHILARD NR+ I LNTIPLFVQLLYS
Sbjct: 538 AQRHVA-AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSS 596
Query: 607 IENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
+ENIQRVAAGVLCELAQDKEAA+AI+AEGA+APL ELLHSRNEG ATYAAAVLFR+SEDK
Sbjct: 597 VENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDK 656
Query: 667 PQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQ 726
DY+KR+SVELT+SLF+ +P AW E A + I EP G D +YR +S
Sbjct: 657 NPDYRKRVSVELTNSLFKHDPAAW-EAAQSMIPI---NEPYG-DDMDATYRPMYSSDVPL 711
Query: 727 DALGMDPMMEHEMGGHHPGADYPVDGLPD 755
D L M M+ DYP+D D
Sbjct: 712 DPLEMHMDMD---------GDYPIDTYSD 731
>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
Length = 1044
Score = 72.4 bits (176), Expect = 2e-12
Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)
Query: 435 KMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVV 494
++ + VGG+E L+ + D + I +L+ L ++ QN V L GLP++
Sbjct: 487 QLAIRDVGGLEVLINLL-----ETDEVKCKIGSLKILKEISHNPQIRQNIVDLG-GLPIM 540
Query: 495 VKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMG 554
V +L P H L I N+A +R+ G I +LV LL AH T+
Sbjct: 541 VNILDSP-HKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTK------ 593
Query: 555 GTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA 614
Q + R E+ AL ++ N+ IR IPL +LL + EN+
Sbjct: 594 -PAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPV 652
Query: 615 AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
G L E A ++ AI+AE L + L+S NE + + A +++ +EDK
Sbjct: 653 VGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDK 704
Score = 70.9 bits (172), Expect = 4e-12
Identities = 105/470 (22%), Positives = 198/470 (42%), Gaps = 51/470 (10%)
Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
I LVK L + A+ ++ + L QE ++A+R GGL+ ++ LL VK
Sbjct: 454 IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIG 513
Query: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPA 356
+ L+ +++ N + + I+ GG +VNI+ + ++ L + + ++ +
Sbjct: 514 SLKILKEISH-NPQIRQNIVDLGGLPIMVNILDS-PHKSLKCLAAETIANVAKFKRARRV 571
Query: 357 IVEAGGMQALG--LHLTDPSQRLVQNCLWTLRNL-------------SDAATKQEGME-- 399
+ + GG+ L L S + Q+ L+ R++ S + T +E +
Sbjct: 572 VRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKA 631
Query: 400 GLLGTLVQLLGSDDINVVTCAAGILSNLTC-NNYKNKMMVCQVGGIEALVRTVLRAGDRE 458
G + L +LL + N++ G L NY+ + ++ IE LV+ + + E
Sbjct: 632 GGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERI--IENLVKNL--NSENE 687
Query: 459 DITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA 518
+ E A+ E + ++ VRLH GL + LL+ + + A G I +
Sbjct: 688 QLQEHCAMAIYQCA----EDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCS 743
Query: 519 LCPANHAPLREQGAIPRLVQLLV---------------RAHQDTQRRT---SMGGTQQ-- 558
+ N RE AI LV LL Q+ + R GG Q
Sbjct: 744 ISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLV 803
Query: 559 QFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVL 618
+ G+ + ++ T A+ A + + ++I L+ + L LL +P +++ AA L
Sbjct: 804 NLLVGIN-QALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWAL 862
Query: 619 CELAQD-KEAAEAIEA-EGATAPLTELLHSRNEGVATYAAAVLFRMSEDK 666
C ++ K+A E + + G + LL S N+ V A + +++D+
Sbjct: 863 CPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQ 912
Score = 69.7 bits (169), Expect = 1e-11
Identities = 105/458 (22%), Positives = 193/458 (42%), Gaps = 45/458 (9%)
Query: 201 TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLH 260
++ DVE ARC A L + S AI K+GGIP L ++L + +++L + TL
Sbjct: 598 SLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQ 657
Query: 261 NLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQIL--AYGNQESKLIILAS 318
+E + A++ ++ +V LN N + + C + ++E++ ++
Sbjct: 658 E-CASEENYRAAIKAERIIENLVKNLNSENEQ---LQEHCAMAIYQCAEDKETRDLVRLH 713
Query: 319 GGPQALVNIM-RTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL 377
GG + L +++ T E+L T + K S+ N E ++ L LTD + +
Sbjct: 714 GGLKPLASLLNNTDNKERLAAVTGAIWK-CSISKENVTKFREYKAIETLVGLLTDQPEEV 772
Query: 378 VQNCLWTL------RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNN 431
+ N + L R K G++ L+ LV + + +N VT A G +
Sbjct: 773 LVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVN-VTKAVGACA----VE 827
Query: 432 YKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEA-EMAQNAVRLHYG 490
++ M++ ++ G+ L L D+ A AL ++A EM ++ V G
Sbjct: 828 PESMMIIDRLDGVRLL--WSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVG---G 882
Query: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL------VRAH 544
L ++V LL + ++ + I N+A N A + + G +P L +L +R H
Sbjct: 883 LELIVNLLKSDNK-EVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHH 941
Query: 545 --QDTQRRTSMGGTQQQFVEGVRMEEIV-----------EGCTGALHILARDVHNRIVIR 591
+ R G + F E + +V AL+ L+ D N I +
Sbjct: 942 LAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMH 1001
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAE 629
+ L + ++ SP +++Q AAG + + + A E
Sbjct: 1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATE 1039
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 67.0 bits (162), Expect = 6e-11
Identities = 88/445 (19%), Positives = 174/445 (39%), Gaps = 55/445 (12%)
Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
A+ LTKLL ED++V + A M+ + ++R ++++++ + +V
Sbjct: 68 AVEPLTKLLTHEDKIV-RRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIH 126
Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
+ L N+S + IF+ GG+ L+++L SP V ++ ++NL+ + +
Sbjct: 127 EFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQ-CRA 185
Query: 272 AVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY 331
++ + ++ LL + L ++A ++ES+ ++ + G L+ I+ T
Sbjct: 186 KLQELNAIPPILDLLKSEYPVIQLLALKTLGVIA-NDKESRTMLRDNQGLDHLIKILETK 244
Query: 332 TYEKL--------------------LWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLT 371
L + T + K+LS ++ ++ +A+
Sbjct: 245 ELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAY 304
Query: 372 DPSQRL------VQNCLWTLRNLSDAATKQEGMEGL-----------------LGTLVQL 408
DP R V+ CL L + TK + + + L+QL
Sbjct: 305 DPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQL 364
Query: 409 LGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICAL 468
L SD+ V AA L+NLT N N + GI+ L+ L + R+ A L
Sbjct: 365 LKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLIN--LLSSKRDGAIANAATVL 422
Query: 469 RHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPAN-HAPL 527
++ + QN +H ++ L + ++++ L C L
Sbjct: 423 TNMAMQEPLRLNIQNHDIMH----AIISPLRSAN--TVVQSKAALAVTATACDVEARTEL 476
Query: 528 REQGAIPRLVQLLVRAHQDTQRRTS 552
R G + LV+LL + + ++ S
Sbjct: 477 RNSGGLEPLVELLRSKNDEVRKHAS 501
Score = 54.3 bits (129), Expect = 4e-07
Identities = 99/441 (22%), Positives = 168/441 (38%), Gaps = 53/441 (12%)
Query: 240 LVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTD 299
+V ML SP + +L A ++ L E K + G ++ + LL + T
Sbjct: 30 VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89
Query: 300 CLQILAYGNQESKLI--------ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCS 351
ILA N KL+ ++A P+ V I S L +S
Sbjct: 90 IFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHE---------FASLCLANMSAEY 140
Query: 352 SNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGL--LGTLVQLL 409
++K I E GG++ L L+ P + +N + + NL + ++ L + ++ LL
Sbjct: 141 TSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLL 200
Query: 410 GSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALR 469
S + V+ A + N+ +++ M+ G++ L++ +L + D+ A+ +
Sbjct: 201 KS-EYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIK-ILETKELNDLHIEALAVIA 258
Query: 470 H-LTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLR 528
+ L ++ Q GL ++ + + K I A P N
Sbjct: 259 NCLEDMDTMVQIQQTG-----GLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFH 313
Query: 529 EQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRI 588
EQ LV LL G++ + + I C + ++D N
Sbjct: 314 EQEVEKCLVALL--------------GSENDGTKIAASQAISAMCENS---GSKDFFNN- 355
Query: 589 VIRGLNTIPLFVQLLYSPIENIQRVAAGVLCEL--AQDKEAAEAIEAEGATAPLTELLHS 646
IP +QLL S E ++ AA L L A A EA+G PL LL S
Sbjct: 356 -----QGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGID-PLINLLSS 409
Query: 647 RNEGVATYAAAVLFRMSEDKP 667
+ +G AA VL M+ +P
Sbjct: 410 KRDGAIANAATVLTNMAMQEP 430
Score = 45.1 bits (105), Expect = 3e-04
Identities = 72/354 (20%), Positives = 142/354 (40%), Gaps = 40/354 (11%)
Query: 353 NKPAIVEAGGMQALGLHLTDPSQRLVQNCLWT---LRNLSDAATKQEGMEGLLGTLVQLL 409
NK ++E G ++ L LT + + +N L + +D ++ + + QL
Sbjct: 59 NKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLA 118
Query: 410 GSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALR 469
+++ + A+ L+N++ Y +K+ + + GG+E L+R L + D+ + ++ +
Sbjct: 119 PEEEVVIHEFASLCLANMSAE-YTSKVQIFEHGGLEPLIR--LLSSPDPDVKKNSMECIY 175
Query: 470 HLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKA----TVGLIRNLALCPANHA 525
+L Q Q +P ++ LL S +P+I+ T+G+I N +
Sbjct: 176 NLVQDFQCRAKLQEL----NAIPPILDLLK--SEYPVIQLLALKTLGVIAN---DKESRT 226
Query: 526 PLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVH 585
LR+ + L+++L + ++ + M +I + TG L L
Sbjct: 227 MLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQ--TGGLKKLLSFAE 284
Query: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLH 645
N S I +IQ+ AA + + A D E + + L LL
Sbjct: 285 N------------------STIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLG 326
Query: 646 SRNEGVATYAAAVLFRMSEDK-PQDYKKRLSVELTSSLFRTEPMAWNETADLGL 698
S N+G A+ + M E+ +D+ + L +++ E A L L
Sbjct: 327 SENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALAL 380
Score = 43.1 bits (100), Expect = 0.001
Identities = 91/471 (19%), Positives = 172/471 (36%), Gaps = 67/471 (14%)
Query: 226 EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVAL 285
E + + G + L K+L + D ++ T + +L K +R + ++A
Sbjct: 58 ENKTTLLELGAVEPLTKLL-THEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQ 116
Query: 286 LNKTN------------VKFLAITTDCLQILAYGNQESKLIILASGGP-------QALVN 326
L A T +QI +G E + +L+S P + + N
Sbjct: 117 LAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYN 176
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLR 386
+++ + L + + +L + S P +++ ++ LG+ D R + L
Sbjct: 177 LVQDFQCRAKLQELNAIPPILDLLKSEYP-VIQLLALKTLGVIANDKESRTMLRDNQGLD 235
Query: 387 NLSDAATKQEGME---GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGG 443
+L +E + L + L D V G L L + + Q
Sbjct: 236 HLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNA 295
Query: 444 IEALVRTVLRAGDREDITEPAI--CALRHLTSRHQEAEMAQNAVRL-------------H 488
+A+ + +R+ E + C + L S + ++A + +
Sbjct: 296 AKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNN 355
Query: 489 YGLPVVVKLLHPPSHWPLIKATVGLIRNLALC-PANHAPLREQGAIPRLVQLLVRAHQDT 547
G+P +++LL + + +A + NL C PAN E I L+ LL +
Sbjct: 356 QGIPQLIQLLKSDNE-EVREAAALALANLTTCNPANANAAAEADGIDPLINLL------S 408
Query: 548 QRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIV--IRGLNTIPLFVQLLYS 605
+R + + M+E + L+I D+ + I+ +R NT+
Sbjct: 409 SKRDGAIANAATVLTNMAMQEPLR-----LNIQNHDIMHAIISPLRSANTV--------- 454
Query: 606 PIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAA 656
+Q AA + A D EA + G PL ELL S+N+ V +A+
Sbjct: 455 ----VQSKAALAVTATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHAS 501
Score = 35.8 bits (81), Expect = 0.16
Identities = 52/263 (19%), Positives = 102/263 (38%), Gaps = 29/263 (11%)
Query: 404 TLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEP 463
T+V +L S + ++ A + +NK + ++G +E L T L + + +
Sbjct: 29 TVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPL--TKLLTHEDKIVRRN 86
Query: 464 AICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPAN 523
A L S + ++ + ++ V+ L P + + + N++ +
Sbjct: 87 ATMIFGILASNNDVKKLLRELDVMNS----VIAQLAPEEEVVIHEFASLCLANMSAEYTS 142
Query: 524 HAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD 583
+ E G + L++LL D ++ + ME ++ L +D
Sbjct: 143 KVQIFEHGGLEPLIRLLSSPDPDVKKNS--------------ME--------CIYNLVQD 180
Query: 584 VHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTEL 643
R ++ LN IP + LL S IQ +A L +A DKE+ + L ++
Sbjct: 181 FQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKI 240
Query: 644 LHSRN-EGVATYAAAVLFRMSED 665
L ++ + A AV+ ED
Sbjct: 241 LETKELNDLHIEALAVIANCLED 263
>gi|224589129 karyopherin 7 [Homo sapiens]
Length = 516
Score = 54.3 bits (129), Expect = 4e-07
Identities = 80/343 (23%), Positives = 142/343 (41%), Gaps = 44/343 (12%)
Query: 198 IVRTMQNTNDVETARCTAGTLHNLSHHREG-LLAIFKSGGIPALVKMLGSPVDSVL-FYA 255
I++ + +++ V + T LS + L + ++G IP +V+ L S + L F A
Sbjct: 75 IIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEA 134
Query: 256 ITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQ-ILAYGNQESKLI 314
L N+ AV G +Q ++ LL+ +NV C Q + A GN
Sbjct: 135 AWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAV------CEQAVWALGN------ 182
Query: 315 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVL----------SVCSSNKPAIVEAGGMQ 364
+A GP+ N++ + LL S L + ++C + P + Q
Sbjct: 183 -IAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQ 241
Query: 365 ALG--LHLTD-PSQRLVQNCLWTLRNLSDAATKQEGM---EGLLGTLVQLLGSDDINVVT 418
L LHL ++ + W L L+D + K+ G G+L LV L+ S ++NV+T
Sbjct: 242 ILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLT 301
Query: 419 CAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTS---RH 475
+ + N+ + M G + L + L ++ I + A AL ++ + H
Sbjct: 302 PSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQ--LLQHNKPSIQKEAAWALSNVAAGPCHH 359
Query: 476 QEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA 518
+ +A + LP +V LL + + K V ++ N A
Sbjct: 360 IQQLLAYDV------LPPLVALL-KNGEFKVQKEAVWMVANFA 395
Score = 31.6 bits (70), Expect = 3.0
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 596 IPLFVQLLYSPIEN-IQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSRNEGVAT 653
IP V+ L S + +Q AA L +A E A+ GA PL ELL S N V
Sbjct: 115 IPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCE 174
Query: 654 YAAAVLFRMSEDKPQ 668
A L ++ D P+
Sbjct: 175 QAVWALGNIAGDGPE 189
>gi|4504897 karyopherin alpha 2 [Homo sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 4e-07
Identities = 96/421 (22%), Positives = 170/421 (40%), Gaps = 60/421 (14%)
Query: 276 AGGLQKMVALLNKTNVKFLAITTD-CLQILAYGNQESKLIILASGGPQALVNIMRT---Y 331
AG + K V+ L +T+ + + L +A G E ++ G A ++++ + +
Sbjct: 118 AGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAH 177
Query: 332 TYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQR-----LVQNCLWTLR 386
E+ +W + SV + +++ G + L L P ++N WTL
Sbjct: 178 ISEQAVWALGNIAGDGSVF---RDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLS 234
Query: 387 NL---SDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGG 443
NL + A + +E +L TLV+LL DD V+ +S LT + MV + G
Sbjct: 235 NLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGV 294
Query: 444 IEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYG-LPVVVKLLHPP- 501
+ LV+ L I PA+ A+ ++ + E Q V + G L V LL P
Sbjct: 295 VPQLVK--LLGASELPIVTPALRAIGNIVTGTDE----QTQVVIDAGALAVFPSLLTNPK 348
Query: 502 ------SHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGG 555
+ W + T G + NH G +P LV +L +A TQ+
Sbjct: 349 TNIQKEATWTMSNITAGRQDQIQQV-VNH------GLVPFLVSVLSKADFKTQKEAVWAV 401
Query: 556 TQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPL----FVQLLYSPIENIQ 611
T + G +E+IV VH I+ +N + + ++ I NI
Sbjct: 402 T--NYTSGGTVEQIV-----------YLVHCGIIEPLMNLLTAKDTKIILVILDAISNIF 448
Query: 612 RVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL---FRMSEDKPQ 668
+ A +L + ++ + IE G + L + NE V + +++ F + E++ Q
Sbjct: 449 QAAE----KLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQ 504
Query: 669 D 669
+
Sbjct: 505 N 505
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/401 (22%), Positives = 157/401 (39%), Gaps = 76/401 (18%)
Query: 122 VQRLAEPSQMLKHAVVNLINYQDDAELATR-----------AIPELTKLLND---EDQVV 167
+++ + QMLK N+ ++ DDA + ++ ++ K +N E+Q+
Sbjct: 38 LRKAKKDDQMLKRR--NVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQ 95
Query: 168 VNKAAVMVHQLSKKEASRHAIMRS--PQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHR 225
+AA + K+ + I P+ VS + RT + E+A S
Sbjct: 96 ATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQT 155
Query: 226 EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVAL 285
+ A+ G IPA + +L SP H ++ AV G + ++
Sbjct: 156 K---AVVDGGAIPAFISLLASP-----------------HAHISEQAVWALGNIAGDGSV 195
Query: 286 LNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLK 345
+K+ A+ L +LA + S LA G L WT S
Sbjct: 196 FRDLVIKYGAV-DPLLALLAVPDMSS----LACG------------YLRNLTWTLS---- 234
Query: 346 VLSVCSSNKPAIVEAGGMQALG-----LHLTDPSQRLVQNCLWTLRNLSDAATKQEGM-- 398
++C + PA Q L LH DP + L C W + L+D ++ GM
Sbjct: 235 --NLCRNKNPAPPIDAVEQILPTLVRLLHHDDP-EVLADTC-WAISYLTDGPNERIGMVV 290
Query: 399 -EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDR 457
G++ LV+LLG+ ++ +VT A + N+ + +V G + V L +
Sbjct: 291 KTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGAL--AVFPSLLTNPK 348
Query: 458 EDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL 498
+I + A + ++T+ Q + Q V H +P +V +L
Sbjct: 349 TNIQKEATWTMSNITAGRQ--DQIQQVVN-HGLVPFLVSVL 386
Score = 37.4 bits (85), Expect = 0.054
Identities = 60/279 (21%), Positives = 116/279 (41%), Gaps = 15/279 (5%)
Query: 145 DAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQN 204
D LA A+P+++ L + + L + + I Q++ +VR + +
Sbjct: 207 DPLLALLAVPDMSSLACG----YLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHH 262
Query: 205 TNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLL 263
+D E T + L+ E + + K+G +P LVK+LG+ ++ A+ + N++
Sbjct: 263 -DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 264 LHQEGAKMAVRLAGGLQKMVALLN--KTNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
+ V AG L +LL KTN++ A T + + G Q+ ++ G
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT--MSNITAGRQDQIQQVVNHGLV 379
Query: 322 QALVNIMRT---YTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLV 378
LV+++ T ++ +W + +V +V G ++ L LT +++
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTNYTSGGTV--EQIVYLVHCGIIEPLMNLLTAKDTKII 437
Query: 379 QNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVV 417
L + N+ AA K E L + + G D I +
Sbjct: 438 LVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEAL 476
>gi|4502247 armadillo repeat protein [Homo sapiens]
Length = 962
Score = 54.3 bits (129), Expect = 4e-07
Identities = 94/404 (23%), Positives = 154/404 (38%), Gaps = 66/404 (16%)
Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
+P ++ ML PVD V A L +L EG K VR GL +VALL+ +
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
Query: 297 TTDCLQILAYG-NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKP 355
L+ L+YG + ++K I GG ALV ++R ++ + L LS K
Sbjct: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
Query: 356 AIVEAGGMQALGLHLTDPSQ------------------RLVQNCLWTLRNLS----DAAT 393
I++ G+Q L + P + +N LRN+S +A
Sbjct: 480 VIID-HGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
Query: 394 KQEGMEGLLGTLVQLLGS-------DDINVVTCAAGILSNLTCNNYK-----NKMMVCQV 441
+ EGL+ L+ L S D+ +V C I+ NL+ + +K ++ +
Sbjct: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVC-IMRNLSYHVHKEVPGADRYQEAEP 597
Query: 442 GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN--------------AVRL 487
G + + V + R D ++ EM +N L
Sbjct: 598 GPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFEL 657
Query: 488 HYGLPVV---VKLLHPPSHWPLIKATVGLIRNLAL-----CPANHAPLREQGAIPRLVQL 539
Y VV + LL ++ ++A G ++NL+ A +R++ +P LV+L
Sbjct: 658 LYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVEL 717
Query: 540 L-------VRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 576
L VRA R S+ + + M E+V A
Sbjct: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNA 761
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 99 FPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRA------ 152
+ +T D+G ++ + A P LA+P + ++ L+ + A +
Sbjct: 301 YEDTADDGGELADER--PAFPMVTAPLAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDP 358
Query: 153 -IPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVET 210
+PE+ +L D V N AA + H + E + + R + + +V + + E
Sbjct: 359 ELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRV-RQLRGLPLLVALLDHPR-AEV 416
Query: 211 ARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQE 267
R G L NLS+ R+ AI GG+PALV++L + D+ + +T TL NL + E
Sbjct: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-E 475
Query: 268 GAKMAVRLAGGLQKM 282
KM + + GLQ +
Sbjct: 476 PLKMVI-IDHGLQTL 489
Score = 31.2 bits (69), Expect = 3.9
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 46/209 (22%)
Query: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCN-NYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
L LV LL V A G L NL+ + NK + GG+ ALVR +LRA ++
Sbjct: 402 LPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDCGGVPALVR-LLRAARDNEV 460
Query: 461 TEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVV-KLLHPPSHW--------------- 504
E L +L+S ++ +M V + +GL + +++ P S W
Sbjct: 461 RELVTGTLWNLSS-YEPLKM----VIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEW 515
Query: 505 -PLIKATVGLIRNLALCPAN-HAPLRE-QGAIPRLVQLLVRA--HQDTQRRTSMGGTQQQ 559
+ K T G +RN++ A LRE +G + L+ L A +DT ++
Sbjct: 516 TTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKS-------- 567
Query: 560 FVEGVRMEEIVEGCTGALHILARDVHNRI 588
VE C + L+ VH +
Sbjct: 568 ----------VENCVCIMRNLSYHVHKEV 586
>gi|32526896 armadillo repeat containing 8 isoform 2 [Homo sapiens]
Length = 659
Score = 50.4 bits (119), Expect = 6e-06
Identities = 56/253 (22%), Positives = 110/253 (43%), Gaps = 9/253 (3%)
Query: 270 KMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMR 329
K + + ++V L++++VK CL L+ Q+ + + L+ +++
Sbjct: 363 KKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQ 422
Query: 330 TYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLS 389
E L+ +S + +L S +K I+E+G ++ L + L N +W L N++
Sbjct: 423 NAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMA 482
Query: 390 DAATKQEGMEGL--LGT--LVQLLGSDDINVVTCAAGILSN-LTCNNYKNKMMVCQVGGI 444
A ++ + L L T L +LL D+NV+ G+L N L+ + +K+M I
Sbjct: 483 FQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQI 542
Query: 445 EALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHW 504
V +L ++ E +C L ++ + A++ + + + +K SH
Sbjct: 543 MQAVTLILEGEHNIEVKEQTLCILANIA----DGTTAKDLIMTNDDILQKIKYYMGHSHV 598
Query: 505 PLIKATVGLIRNL 517
L A + I NL
Sbjct: 599 KLQLAAMFCISNL 611
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 33/223 (14%)
Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
+P +++ML SV A L +L K +R GG+Q +V LL+ +
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
Query: 297 TTDCLQILAYG--NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
L+ L YG N ++K+ + GG ALV ++R T ++ + VL LS C + K
Sbjct: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
Query: 355 PAIVEAGGMQALGLHLTDP------------------SQRLVQNCLWTLRNLSDAATKQ- 395
I++ + L + P S ++++N LRN+S A +
Sbjct: 672 MPIIQ-DALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEAR 730
Query: 396 ------EGM-EGLLGTLVQLLGSDDIN---VVTCAAGILSNLT 428
+G+ + LL + LGS +I+ V C IL NL+
Sbjct: 731 RRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVC-ILRNLS 772
Score = 39.7 bits (91), Expect = 0.011
Identities = 89/406 (21%), Positives = 160/406 (39%), Gaps = 75/406 (18%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212
+PE+ ++L + V + AA + L + A +R + +V + + E R
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRM-TEVHR 610
Query: 213 CTAGTLHNLSHHR---EGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGA 269
G L NL + + + +A+ GGIPALV++L D + +T + L +
Sbjct: 611 SACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDAL 670
Query: 270 KMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMR 329
KM + +Q +A+L I+ + E+ P ++
Sbjct: 671 KMPI-----IQDALAVLTNA------------VIIPHSGWEN--------SPLQDDRKIQ 705
Query: 330 TYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHL-------TDPSQRLVQNCL 382
++ + L T + V S + + E G+ L++ ++ + V+NC+
Sbjct: 706 LHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCV 765
Query: 383 WTLRNLSD--AATKQEGMEGLLGTLVQLLGSDDINVVTCAAG---ILSNLTCNNYKNKMM 437
LRNLS AA +G Q +G+D+++ + C + C K K
Sbjct: 766 CILRNLSYRLAAETSQG---------QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKK 816
Query: 438 VCQ-----VG----------GIEAL--------VRTVLRAGDREDITEPAICALRHLTSR 474
Q VG GI+ L T+L D E A AL++L +
Sbjct: 817 KSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAG 876
Query: 475 HQE-AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLAL 519
+ + + AVR GLP++V+LL + ++ A +RN+AL
Sbjct: 877 SWKWSVYIRAAVRKEKGLPILVELLRIDND-RVVCAVATALRNMAL 921
Score = 35.8 bits (81), Expect = 0.16
Identities = 41/176 (23%), Positives = 77/176 (43%), Gaps = 8/176 (4%)
Query: 402 LGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDIT 461
L ++Q+L +V + AA L +L + K K + + GGI+ LV L ++
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVD--LLDHRMTEVH 609
Query: 462 EPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCP 521
A ALR+L + + A++ G+P +V+LL + + + G++ NL+ C
Sbjct: 610 RSACGALRNLVYGKANDDN-KIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCD 668
Query: 522 ANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGAL 577
A P+ Q A+ L ++ H + + Q + +++ TG L
Sbjct: 669 ALKMPI-IQDALAVLTNAVIIPHSGWENSPLQDDRKIQ----LHSSQVLRNATGCL 719
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)
Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
L+NLT + NK +C + G + L++ + ED+ + LR+L+ R ++
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561
Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
+R + +++ +K+ + + NL A C N A + GA+ LV L
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621
Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
R+ +T GG + V ++A + +R ++R N + +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666
Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
Q L S I A G L L A++ + EA+ GA + L L+HS+++ +A +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
+ ++P YK + SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749
Score = 35.8 bits (81), Expect = 0.16
Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)
Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
+HA+ L Q AEL + E+ L ND + + + A M + L+ + + A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521
Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
+ + A+V +++ ++ + + A L NLS + + + G + AL++ L
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580
Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
+S L ++ L NL H K + G + FL T L Y
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623
Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
+Q + L I+ SGG I+R V +++ ++ + E +Q L
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666
Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
HL S +V N TL NLS K QE + G + L L+ S + +A L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 425 SNLTCN 430
NL N
Sbjct: 727 RNLMAN 732
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)
Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
L+NLT + NK +C + G + L++ + ED+ + LR+L+ R ++
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561
Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
+R + +++ +K+ + + NL A C N A + GA+ LV L
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621
Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
R+ +T GG + V ++A + +R ++R N + +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666
Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
Q L S I A G L L A++ + EA+ GA + L L+HS+++ +A +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
+ ++P YK + SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749
Score = 35.8 bits (81), Expect = 0.16
Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)
Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
+HA+ L Q AEL + E+ L ND + + + A M + L+ + + A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521
Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
+ + A+V +++ ++ + + A L NLS + + + G + AL++ L
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580
Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
+S L ++ L NL H K + G + FL T L Y
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623
Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
+Q + L I+ SGG I+R V +++ ++ + E +Q L
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666
Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
HL S +V N TL NLS K QE + G + L L+ S + +A L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 425 SNLTCN 430
NL N
Sbjct: 727 RNLMAN 732
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/263 (24%), Positives = 115/263 (43%), Gaps = 22/263 (8%)
Query: 424 LSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQN 483
L+NLT + NK +C + G + L++ + ED+ + LR+L+ R ++
Sbjct: 505 LTNLTFGDVANKATLCSMKGCMRALVAQLKS-ESEDLQQVIASVLRNLSWRADVN--SKK 561
Query: 484 AVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNL-ALCPANHAPL-REQGAIPRLVQLLV 541
+R + +++ +K+ + + NL A C N A + GA+ LV L
Sbjct: 562 TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT 621
Query: 542 -RAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFV 600
R+ +T GG + V ++A + +R ++R N + +
Sbjct: 622 YRSQTNTLAIIESGGGILRNVSS---------------LIATNEDHRQILRENNCLQTLL 666
Query: 601 QLLYSPIENIQRVAAGVLCEL-AQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVL 659
Q L S I A G L L A++ + EA+ GA + L L+HS+++ +A +AA L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 660 FRMSEDKPQDYKKRLSVELTSSL 682
+ ++P YK + SSL
Sbjct: 727 RNLMANRPAKYKDANIMSPGSSL 749
Score = 35.8 bits (81), Expect = 0.16
Identities = 74/306 (24%), Positives = 124/306 (40%), Gaps = 44/306 (14%)
Query: 133 KHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVM-VHQLSKKEASRHAIMRS 191
+HA+ L Q AEL + E+ L ND + + + A M + L+ + + A + S
Sbjct: 463 RHAMNELGGLQAIAELL-QVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS 521
Query: 192 PQ-MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKM-LGSP 247
+ + A+V +++ ++ + + A L NLS + + + G + AL++ L
Sbjct: 522 MKGCMRALVAQLKSESE-DLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVK 580
Query: 248 VDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG 307
+S L ++ L NL H K + G + FL T L Y
Sbjct: 581 KESTLKSVLSALWNLSAHCTENKADICAVDGA-----------LAFLVGT------LTYR 623
Query: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
+Q + L I+ SGG I+R V +++ ++ + E +Q L
Sbjct: 624 SQTNTLAIIESGG-----GILRN------------VSSLIATNEDHRQILRENNCLQTLL 666
Query: 368 LHLTDPSQRLVQNCLWTLRNLSDAATK-QEGM--EGLLGTLVQLLGSDDINVVTCAAGIL 424
HL S +V N TL NLS K QE + G + L L+ S + +A L
Sbjct: 667 QHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL 726
Query: 425 SNLTCN 430
NL N
Sbjct: 727 RNLMAN 732
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652
Query: 541 VRAHQDT 547
Q++
Sbjct: 653 PGGQQNS 659
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652
Query: 541 VRAHQDT 547
Q++
Sbjct: 653 PGGQQNS 659
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652
Query: 541 VRAHQDT 547
Q++
Sbjct: 653 PGGQQNS 659
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 35.0 bits (79), Expect = 0.27
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAV 273
KM +
Sbjct: 384 IKMEI 388
Score = 33.1 bits (74), Expect = 1.0
Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)
Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
K GIP LV +L P V A L N+ + K+A++ G+ +V LL K
Sbjct: 305 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 364
Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
L IT + ++ + + +++ I+ G + N R +E
Sbjct: 365 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 424
Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
+L T+ L+ V S S + + E G+ + + D +LV+NC+ LRN
Sbjct: 425 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 484
Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
LS ++ E + + G + G + + +
Sbjct: 485 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544
Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
G E L + ++L+ I E + A+++L + R ++A
Sbjct: 545 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 604
Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 605 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 662
Query: 545 QDT 547
Q++
Sbjct: 663 QNS 665
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652
Query: 541 VRAHQDT 547
Q++
Sbjct: 653 PGGQQNS 659
>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
Length = 861
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 384 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 414
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 415 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 474
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 475 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 534
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 535 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 594
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 595 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 652
Query: 541 VRAHQDT 547
Q++
Sbjct: 653 PGGQQNS 659
>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
Length = 867
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 238 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 297
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 298 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 357
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 358 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 409
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 410 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 453
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 454 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 497
Score = 35.0 bits (79), Expect = 0.27
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 327 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 383
Query: 269 AKMAV 273
KM +
Sbjct: 384 IKMEI 388
Score = 33.1 bits (74), Expect = 1.0
Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)
Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
K GIP LV +L P V A L N+ + K+A++ G+ +V LL K
Sbjct: 305 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 364
Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
L IT + ++ + + +++ I+ G + N R +E
Sbjct: 365 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 424
Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
+L T+ L+ V S S + + E G+ + + D +LV+NC+ LRN
Sbjct: 425 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 484
Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
LS ++ E + + G + G + + +
Sbjct: 485 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544
Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
G E L + ++L+ I E + A+++L + R ++A
Sbjct: 545 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 604
Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 605 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 662
Query: 545 QDT 547
Q++
Sbjct: 663 QNS 665
>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753
Query: 541 VRAHQDT 547
Q++
Sbjct: 754 PGGQQNS 760
>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753
Query: 541 VRAHQDT 547
Q++
Sbjct: 754 PGGQQNS 760
>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753
Query: 541 VRAHQDT 547
Q++
Sbjct: 754 PGGQQNS 760
>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
Length = 941
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753
Query: 541 VRAHQDT 547
Q++
Sbjct: 754 PGGQQNS 760
>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
Length = 962
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 37.4 bits (85), Expect = 0.054
Identities = 94/427 (22%), Positives = 162/427 (37%), Gaps = 66/427 (15%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVN-- 326
KM + + A+T + +I+ G + N
Sbjct: 485 IKMEI---------------VDHALHALTDE--------------VIIPHSGWEREPNED 515
Query: 327 -IMRTYTYEKLLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRL 377
R +E +L T+ L+ V S S + + E G+ + + D +L
Sbjct: 516 CKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKL 575
Query: 378 VQNCLWTLRNLSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAG----ILSNLTC 429
V+NC+ LRNLS ++ E + + G + G + +
Sbjct: 576 VENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKGKKPIEDPAN 635
Query: 430 NNYKNKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHL-TSRHQEAEM 480
+ G E L + ++L+ I E + A+++L R
Sbjct: 636 DTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY 695
Query: 481 AQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
++A+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 696 IRSALRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNL 753
Query: 541 VRAHQDT 547
Q++
Sbjct: 754 PGGQQNS 760
>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
Length = 968
Score = 47.0 bits (110), Expect = 7e-05
Identities = 71/284 (25%), Positives = 119/284 (41%), Gaps = 46/284 (16%)
Query: 221 LSHHREGLLAIFKS---GG----------IPALVKMLGSPVDSVLFYAITTLHNLLLHQE 267
L+ H G LA S GG +P ++ MLG +D+V A L +L +
Sbjct: 339 LAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRND 398
Query: 268 GAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYG-NQESKLIILASGGPQALVN 326
K VR G+ +V LL+ + L+ +++G +Q++K+ I G ALV
Sbjct: 399 KVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVR 458
Query: 327 IMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLH-LTDPSQRLVQNCLWTL 385
++R L + L LS S K IV+ LH LTD + ++ + W
Sbjct: 459 LLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDH------ALHALTD--EVIIPHSGWER 510
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTC--NNYKNKMMVCQVGG 443
D + E +V+T AG L N++ + + K+ C G
Sbjct: 511 EPNEDCKPRHIEWE---------------SVLTNTAGCLRNVSSERSEARRKLRECD-GL 554
Query: 444 IEALVRTVLRAGDRED----ITEPAICALRHLTSR-HQEAEMAQ 482
++AL+ V ++D + E +C LR+L+ + H+E A+
Sbjct: 555 VDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAE 598
Score = 35.0 bits (79), Expect = 0.27
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTN-DVETA 211
+PE+ +L V + AA + L + +R + + +V + + +V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 212 RCTAGTLHNLSHHRE--GLLAIFKSGGIPALVKMLGSPVDSVLFYAIT-TLHNLLLHQEG 268
C G L N+S R+ +AI G+PALV++L D L IT TL NL H +
Sbjct: 428 AC--GALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH-DS 484
Query: 269 AKMAV 273
KM +
Sbjct: 485 IKMEI 489
Score = 33.1 bits (74), Expect = 1.0
Identities = 79/363 (21%), Positives = 139/363 (38%), Gaps = 50/363 (13%)
Query: 233 KSGGIPALVKMLGSPVDSVLFYAITTLHNLLL-HQEGAKMAVRLAGGLQKMVALLNKTNV 291
K GIP LV +L P V A L N+ + K+A++ G+ +V LL K
Sbjct: 406 KLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARD 465
Query: 292 KFLA--ITTDCLQILAYGNQESKLI-----------ILASGGPQALVNI---MRTYTYEK 335
L IT + ++ + + +++ I+ G + N R +E
Sbjct: 466 MDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES 525
Query: 336 LLWTTSRVLK-VLSVCSSNKPAIVEAGGMQALGLHLT-------DPSQRLVQNCLWTLRN 387
+L T+ L+ V S S + + E G+ + + D +LV+NC+ LRN
Sbjct: 526 VLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRN 585
Query: 388 LSDAATKQ----EGMEGLLGTLVQLLGSDDINVVTCAAGI----------LSNLTCNNYK 433
LS ++ E + + G + G + + +
Sbjct: 586 LSYQVHREIPQAERYQEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 645
Query: 434 NKMMVCQVGGIEALVR--------TVLRAGDREDITEPAICALRHLTS-RHQEAEMAQNA 484
G E L + ++L+ I E + A+++L + R ++A
Sbjct: 646 FPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSA 705
Query: 485 VRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAH 544
+R L + LL H ++KA G +RNLA+ A + L + AIP LV+ L
Sbjct: 706 LRQEKALSAIADLL-TNEHERVVKAASGALRNLAV-DARNKELIGKHAIPNLVKNLPGGQ 763
Query: 545 QDT 547
Q++
Sbjct: 764 QNS 766
>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
Length = 1363
Score = 46.6 bits (109), Expect = 9e-05
Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 21/370 (5%)
Query: 153 IPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETAR 212
IP L LL + K ++ +S +++ HA++ + + S I + + +V + R
Sbjct: 673 IPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHS-R 731
Query: 213 CTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA 272
C A L++++ E I K GIP+L+ +L +++VL + + L + E + A
Sbjct: 732 C-AVILYDIAQC-ENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQRA 789
Query: 273 VRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYT 332
VR GL ++ L+ + A+++ + + N+E + I G LV + +
Sbjct: 790 VREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKG-- 847
Query: 333 YEKLLWTTSRVLKVLSVCSSN---KPAIVEAGGMQALGLHLTDPSQRLVQN----CLWTL 385
+++ + V S+ S N + A +E + L L L Q V+ LW L
Sbjct: 848 -KQISVQMKGAMAVESLASHNALIQKAFLEKSLTKYL-LKLLKAFQIDVKEQGAVALWAL 905
Query: 386 RNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIE 445
+ K + ++ +L S + + L+ ++ ++ +C+ GI
Sbjct: 906 AGQTLKQQKYMAEQIGYSFIINMLLSPSAKMQYVGGEAVIALSKDSRMHQNQICEGNGIA 965
Query: 446 ALVRTVLRAGDREDITEPAICALRHLT--SRHQEAEMAQNAVRLHYGLPVVVKLL--HPP 501
LVR + + E I A+ + H ++Q V PV+++LL HP
Sbjct: 966 PLVRLLRISTIAEGTLLSVIRAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQLLRNHPS 1025
Query: 502 SHWPLIKATV 511
P IK V
Sbjct: 1026 ---PNIKVEV 1032
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/214 (22%), Positives = 87/214 (40%), Gaps = 21/214 (9%)
Query: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRR 550
+P ++ LL S L TVGL+ N++ + L E G IP L+ LLV + R
Sbjct: 673 IPALINLLKS-SKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSR 731
Query: 551 TSM------------------GGTQQQFVEGVRMEEIVEGCTGALHILA-RDVHNRIVIR 591
++ G + + +E ++ + +L + +N+ +R
Sbjct: 732 CAVILYDIAQCENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQRAVR 791
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSRNEG 650
+P ++ L S + ++ V++ + E+ +D KE +AI EGA PL L +
Sbjct: 792 EHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQIS 851
Query: 651 VATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFR 684
V A + ++ K L LT L +
Sbjct: 852 VQMKGAMAVESLASHNALIQKAFLEKSLTKYLLK 885
Score = 33.5 bits (75), Expect = 0.78
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 580 LARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAP 639
LA D + R ++ TIP + LL S +Q G+L ++ K A A+ G
Sbjct: 658 LANDQYWRCILDA-GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPS 716
Query: 640 LTELLHSRNEGVATYAAAVLFRMSEDKPQD 669
L LL V + A +L+ +++ + +D
Sbjct: 717 LINLLVCDEPEVHSRCAVILYDIAQCENKD 746
Score = 30.4 bits (67), Expect = 6.6
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 400 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRED 459
G + L+ LL S I + G+LSN++ + +V + GGI +L+ L D +
Sbjct: 671 GTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALV-EAGGIPSLIN--LLVCDEPE 727
Query: 460 ITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLAL 519
+ L + + +A+ + G+P ++ LL+ L+ + IR L +
Sbjct: 728 VHSRCAVILYDIAQCENKDVIAK-----YNGIPSLINLLNLNIENVLVN-VMNCIRVLCI 781
Query: 520 CPANH-APLREQGAIPRLVQLL 540
N+ +RE +P L++ L
Sbjct: 782 GNENNQRAVREHKGLPYLIRFL 803
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 42.0 bits (97), Expect = 0.002
Identities = 104/471 (22%), Positives = 180/471 (38%), Gaps = 84/471 (17%)
Query: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
+P ++ ML SV A L +L KM V GG++ +V LL+ ++
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
Query: 297 TTDCLQILAYGNQ--ESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
L+ L +G E+K+ + GG AL+ ++R ++ + VL LS C + K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
Query: 355 PAIVEAGGMQALGLHLTDP------------------SQRLVQNCLWTLRNLSDA---AT 393
I+ + L + P + +++N LRNLS A A
Sbjct: 650 MTIIR-DALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEAR 708
Query: 394 KQ-EGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCN----NYKNKMMVCQVG--GIEA 446
KQ EGL+ +L+ ++ + +N + + N C +Y+ ++ V Q G+
Sbjct: 709 KQMRSCEGLVDSLLYVIHT-CVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNE 767
Query: 447 LVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGL------------PVV 494
L + + +D +EP+ + + E + V GL P V
Sbjct: 768 LDDLLGKESPSKD-SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSV 826
Query: 495 VK----LLHPPSHWPLIKATVGLIRNLA-----LCPANHAPLREQGAIPRLVQLLVRAHQ 545
VK LL S+ ++ + G ++NL+ A +R++ +P LV+LL
Sbjct: 827 VKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELL---RM 883
Query: 546 DTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLL-- 603
D R +V AL +A DV N+ +I G + V L
Sbjct: 884 DNDR-------------------VVSSVATALRNMALDVRNKELI-GKYAMRDLVNRLPG 923
Query: 604 -YSPIENIQRVAAGVLCEL----AQDKEAAEAIEAEGATAPLTELLHSRNE 649
P A + C L +++ E A+A+ G L + R +
Sbjct: 924 GNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGD 974
Score = 36.2 bits (82), Expect = 0.12
Identities = 93/434 (21%), Positives = 162/434 (37%), Gaps = 107/434 (24%)
Query: 143 QDDAELATR--AIPELTKLLNDE-DQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIV 199
+D E A R +PE+ +L + V N AA + H + + R + +
Sbjct: 518 KDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVD 577
Query: 200 RTMQNTNDVETARCTAGTLHNLSHHR---EGLLAIFKSGGIPALVKMLGSPVDSVLFYAI 256
+V+ C G L NL + E +A+ GGIPAL+++L +D+ + +
Sbjct: 578 LLDHRVLEVQKNAC--GALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELV 635
Query: 257 TTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT-----------------NVKF-----L 294
T + L + KM + ++ ++ L T +KF L
Sbjct: 636 TGVLWNLSSCDAVKMTI-----IRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
Query: 295 AITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNK 354
TT CL+ L+ +E++ + + G +L V+ C
Sbjct: 691 RNTTGCLRNLSSAGEEARKQMRSCEG------------------LVDSLLYVIHTC---- 728
Query: 355 PAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLG--TLVQLLGSD 412
++ +D + V+NC+ TLRNLS + LLG L LLG +
Sbjct: 729 -------------VNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKE 775
Query: 413 DINVVTCAAGILSNLTC--NNYKNKMMVCQ------VGGIEALVR--------------- 449
+ S +C K K Q VG I L +
Sbjct: 776 -------SPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828
Query: 450 ---TVLRAGDREDITEPAICALRHLTSRHQE-AEMAQNAVRLHYGLPVVVKLLHPPSHWP 505
T+L E + +L++L++ + + A + AVR GLP++V+LL +
Sbjct: 829 PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDND-R 887
Query: 506 LIKATVGLIRNLAL 519
++ + +RN+AL
Sbjct: 888 VVSSVATALRNMAL 901
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 19/152 (12%)
Query: 192 PQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGL-----LAIFKSGGIPALVKMLGS 246
P +V + + +++ T +AG+L NLS A+ K G+P LV++L
Sbjct: 824 PSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRM 883
Query: 247 PVDSVLFYAITTLHNLLLHQEGAK---------MAVRLAGGLQKMVALLNKTNVKFLAIT 297
D V+ T L N+ L + + RL GG V L ++T +A
Sbjct: 884 DNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSV-LSDET----MAAI 938
Query: 298 TDCLQILAYGNQESKLIILASGGPQALVNIMR 329
L + N E+ + SGG + LVNI +
Sbjct: 939 CCALHEVTSKNMENAKALADSGGIEKLVNITK 970
Score = 31.2 bits (69), Expect = 3.9
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 11/116 (9%)
Query: 354 KPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE-----GMEGLLGTLVQL 408
+ A+ + G+ L L + R+V + LRN++ +E M L+ L
Sbjct: 865 RAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG 924
Query: 409 LG----SDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDI 460
G SD+ C A L +T N +N + GGIE LV GDR +
Sbjct: 925 NGPSVLSDETMAAICCA--LHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSL 978
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,454,699
Number of Sequences: 37866
Number of extensions: 1232500
Number of successful extensions: 3317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2942
Number of HSP's gapped (non-prelim): 243
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.