Search of human proteins with 14591919

Search of human proteins with 14591919

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo
sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo sa...   625   e-179
gi|14591921 SEC22 vesicle trafficking protein homolog C isoform ...   218   7e-57
gi|4759088 SEC22 vesicle trafficking protein homolog C isoform b...   160   1e-39
gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo sa...    99   5e-21
gi|5032137 vesicle-associated membrane protein 7 isoform 1 [Homo...    41   0.002
gi|9257222 forkhead box O1 [Homo sapiens]                              39   0.004
gi|5730031 secretory carrier membrane protein 2 [Homo sapiens]         30   2.7  
gi|223468574 vesicle-associated membrane protein 7 isoform 2 [Ho...    30   2.7  
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...    29   6.0  
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...    29   6.0  
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...    29   6.0  
gi|4758576 HUS1 checkpoint protein [Homo sapiens]                      29   6.0  
gi|82617624 beta-carotene dioxygenase 2 isoform a [Homo sapiens]       28   7.8  
gi|82617628 beta-carotene dioxygenase 2 isoform b [Homo sapiens]       28   7.8  

>gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo
           sapiens]
          Length = 307

 Score =  625 bits (1612), Expect = e-179
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI 60
           MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
Sbjct: 1   MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI 60

Query: 61  NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ 120
           NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ
Sbjct: 61  NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ 120

Query: 121 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS 180
           RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS
Sbjct: 121 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS 180

Query: 181 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY 240
           AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY
Sbjct: 181 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY 240

Query: 241 QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG 300
           QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG
Sbjct: 241 QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG 300

Query: 301 KAPDYDV 307
           KAPDYDV
Sbjct: 301 KAPDYDV 307


>gi|14591921 SEC22 vesicle trafficking protein homolog C isoform a
           [Homo sapiens]
          Length = 303

 Score =  218 bits (554), Expect = 7e-57
 Identities = 123/307 (40%), Positives = 178/307 (57%), Gaps = 4/307 (1%)

Query: 1   MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI 60
           MS+I  A V+RVRDGLPLSASTD+  +    E R+  K L+ +LAQ P R + +   ++I
Sbjct: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60

Query: 61  NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ 120
           +F S   V+ M +C+   P  +AF FL+ L  EF  +Y+      A RPY F+EFD+ IQ
Sbjct: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120

Query: 121 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS 180
           + K  +N   S   + +L  +Q E+KL+PP  +++ +   ANGV +  +          +
Sbjct: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHT----PMHLEPA 176

Query: 181 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY 240
            + R+EP T  GI+  IL+++C ALNLIRG H  E  LQ   ++   I+AF +   AC++
Sbjct: 177 PNFRMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIF 236

Query: 241 QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG 300
           QCYL ++Y+  R +K  L    ICL NMYL+ LRNLWQ+ FH+ V    + QI  RQ Q 
Sbjct: 237 QCYLYLFYSPARTMKVVLMLLFICLGNMYLHGLRNLWQILFHIGVAFLSSYQILTRQLQE 296

Query: 301 KAPDYDV 307
           K  D  V
Sbjct: 297 KQSDCGV 303


>gi|4759088 SEC22 vesicle trafficking protein homolog C isoform b
           [Homo sapiens]
          Length = 250

 Score =  160 bits (405), Expect = 1e-39
 Identities = 92/241 (38%), Positives = 139/241 (57%), Gaps = 4/241 (1%)

Query: 1   MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI 60
           MS+I  A V+RVRDGLPLSASTD+  +    E R+  K L+ +LAQ P R + +   ++I
Sbjct: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60

Query: 61  NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ 120
           +F S   V+ M +C+   P  +AF FL+ L  EF  +Y+      A RPY F+EFD+ IQ
Sbjct: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120

Query: 121 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS 180
           + K  +N   S   + +L  +Q E+KL+PP  +++ +   ANGV +  +          +
Sbjct: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHT----PMHLEPA 176

Query: 181 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY 240
            + R+EP T  GI+  IL+++C ALNLIRG H  E  LQ   ++   I+AF +   AC++
Sbjct: 177 PNFRMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIF 236

Query: 241 Q 241
           Q
Sbjct: 237 Q 237


>gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo
           sapiens]
          Length = 215

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 58/147 (39%), Positives = 85/147 (57%), Gaps = 7/147 (4%)

Query: 3   MILSASVIRVRDGLPLSASTDYEQSTG--MQECRKYFKMLSRKL-AQLPDRCTLKTGHYN 59
           M+L   + RV DGLPL+AS   ++ +G  +Q+ +   K L RKL  Q P RCTL+ G   
Sbjct: 1   MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMT 60

Query: 60  INFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFI 119
            ++I   GV  ++LC   +P  LAF++L++L  EF   +   K  T  RPY FIEFD FI
Sbjct: 61  FHYIIEQGVCDLVLCEAAFPKTLAFAYLEDLHSEFDEQHG-KKVPTVSRPYSFIEFDTFI 119

Query: 120 QRTKQRYNNPRSLSTKINLSDMQTEIK 146
           Q+TK+ Y +      + NL  + TE++
Sbjct: 120 QKTKKLYIDS---CARRNLGSINTELQ 143


>gi|5032137 vesicle-associated membrane protein 7 isoform 1 [Homo
           sapiens]
          Length = 220

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 27/115 (23%), Positives = 58/115 (50%), Gaps = 6/115 (5%)

Query: 36  YFKMLSRKLAQLP---DRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSFLDELQK 92
           + ++  + LA++P   ++ T   G+Y  ++I    + Y+ +  +++    AF+FL+E++K
Sbjct: 25  FLEVTEQILAKIPSENNKLTYSHGNYLFHYICQDRIVYLCITDDDFERSRAFNFLNEIKK 84

Query: 93  EFITTYNMMKTNTAVRPYCF-IEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIK 146
            F TTY   +  TA+ PY    EF + +    + ++  + L   +       E+K
Sbjct: 85  RFQTTYG-SRAQTAL-PYAMNSEFSSVLAAQLKHHSENKGLDKVMETQAQVDELK 137


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 12/90 (13%)

Query: 138 LSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVGFI 197
           L+ ++T +++  P+ + M  LG  + V+S     C G G++   HQ   P+ L G+  FI
Sbjct: 555 LTQVKTPVQVPLPHPMQMSALGGYSSVSS-----CNGYGRMGLLHQEKLPSDLDGM--FI 607

Query: 198 LSLLCGALNLIRGFHAIESLLQSDGDDFNY 227
             L C   ++IR       L+  D  DFN+
Sbjct: 608 ERLDCDMESIIR-----NDLMDGDTLDFNF 632


>gi|5730031 secretory carrier membrane protein 2 [Homo sapiens]
          Length = 329

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 2/54 (3%)

Query: 220 SDGDDFNYIIAFFLGTAACLYQCYLLVYYTGWR--NVKSFLTFGLICLCNMYLY 271
           S G DF   I +FL    C + C+    Y  +R  N  SF  F  +  C + +Y
Sbjct: 179 SKGVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIY 232


>gi|223468574 vesicle-associated membrane protein 7 isoform 2 [Homo
           sapiens]
          Length = 179

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 76  ENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCF-IEFDNFIQRTKQRYNNPRSLST 134
           E++    AF+FL+E++K F TTY   +  TA+ PY    EF + +    + ++  + L  
Sbjct: 27  EDFERSRAFNFLNEIKKRFQTTYG-SRAQTAL-PYAMNSEFSSVLAAQLKHHSENKGLDK 84

Query: 135 KINLSDMQTEIK 146
            +       E+K
Sbjct: 85  VMETQAQVDELK 96


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 10/19 (52%), Positives = 14/19 (73%)

Query: 238 CLYQCYLLVYYTGWRNVKS 256
           CL  C++LVY+  W+ VKS
Sbjct: 238 CLLACWVLVYFCVWKGVKS 256


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 10/19 (52%), Positives = 14/19 (73%)

Query: 238 CLYQCYLLVYYTGWRNVKS 256
           CL  C++LVY+  W+ VKS
Sbjct: 123 CLLACWVLVYFCVWKGVKS 141


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 10/19 (52%), Positives = 14/19 (73%)

Query: 238 CLYQCYLLVYYTGWRNVKS 256
           CL  C++LVY+  W+ VKS
Sbjct: 238 CLLACWVLVYFCVWKGVKS 256


>gi|4758576 HUS1 checkpoint protein [Homo sapiens]
          Length = 280

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 12/72 (16%)

Query: 33 CRKYFKMLSRKLAQLPDRCTLKTGHYNINFI-----SSLGVSYMMLCTENYPNVLAFSFL 87
          C  +F  +S  +A+L   CTL+     +NFI     ++ GVS  M C     N     F 
Sbjct: 12 CLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVS--MWCELEQEN-----FF 64

Query: 88 DELQKEFITTYN 99
          +E Q E ++  N
Sbjct: 65 NEFQMEGVSAEN 76


>gi|82617624 beta-carotene dioxygenase 2 isoform a [Homo sapiens]
          Length = 579

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 33  CRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTE-NYPNVLAFSFLDELQ 91
           C+  F+    +  +LP +    T + N+N++   G  Y  LCTE N+ N +    L++ +
Sbjct: 154 CKNVFERFMSRF-ELPGKAAAMTDNTNVNYVRYKGDYY--LCTETNFMNKVDIETLEKTE 210

Query: 92  K 92
           K
Sbjct: 211 K 211


>gi|82617628 beta-carotene dioxygenase 2 isoform b [Homo sapiens]
          Length = 545

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 33  CRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTE-NYPNVLAFSFLDELQ 91
           C+  F+    +  +LP +    T + N+N++   G  Y  LCTE N+ N +    L++ +
Sbjct: 120 CKNVFERFMSRF-ELPGKAAAMTDNTNVNYVRYKGDYY--LCTETNFMNKVDIETLEKTE 176

Query: 92  K 92
           K
Sbjct: 177 K 177


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,609,510
Number of Sequences: 37866
Number of extensions: 418145
Number of successful extensions: 1188
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1176
Number of HSP's gapped (non-prelim): 14
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.