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Search of human proteins with 9951915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9951915 adenosylhomocysteinase isoform 1 [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9951915 adenosylhomocysteinase isoform 1 [Homo sapiens] 879 0.0
gi|239937451 adenosylhomocysteinase isoform 2 [Homo sapiens] 823 0.0
gi|21361647 S-adenosylhomocysteine hydrolase-like 1 [Homo sapiens] 444 e-125
gi|195539349 S-adenosylhomocysteine hydrolase-like 2 isoform d [... 442 e-124
gi|195539347 S-adenosylhomocysteine hydrolase-like 2 isoform c [... 442 e-124
gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b [... 442 e-124
gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [H... 442 e-124
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo... 36 0.059
gi|186928839 retinol dehydrogenase 12 [Homo sapiens] 32 1.5
gi|6912396 glyoxylate reductase/hydroxypyruvate reductase [Homo ... 31 1.9
gi|229576906 F-box and WD repeat domain containing 12 isoform 3 ... 31 2.5
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ... 31 2.5
gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens] 30 4.3
gi|47157315 Janus kinase 3 [Homo sapiens] 29 7.3
gi|13375746 hypothetical protein LOC79624 [Homo sapiens] 29 7.3
gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens] 29 7.3
gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens] 29 7.3
gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens] 29 7.3
gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens] 29 7.3
gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens] 29 7.3
gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens] 29 7.3
>gi|9951915 adenosylhomocysteinase isoform 1 [Homo sapiens]
Length = 432
Score = 879 bits (2271), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET 60
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
Sbjct: 1 MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET 60
Query: 61 AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF 120
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
Sbjct: 61 AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF 120
Query: 121 KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV 180
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
Sbjct: 121 KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV 180
Query: 181 NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI 240
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
Sbjct: 181 NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI 240
Query: 241 ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG 300
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
Sbjct: 241 ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG 300
Query: 301 HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN 360
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
Sbjct: 301 HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN 360
Query: 361 SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS 420
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
Sbjct: 361 SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS 420
Query: 421 CDGPFKPDHYRY 432
CDGPFKPDHYRY
Sbjct: 421 CDGPFKPDHYRY 432
>gi|239937451 adenosylhomocysteinase isoform 2 [Homo sapiens]
Length = 404
Score = 823 bits (2127), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 29 MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 88
MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA
Sbjct: 1 MPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHA 60
Query: 89 AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 148
AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP
Sbjct: 61 AAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLP 120
Query: 149 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 208
GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD
Sbjct: 121 GIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATD 180
Query: 209 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 268
VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE
Sbjct: 181 VMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 240
Query: 269 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 328
GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY
Sbjct: 241 GNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRY 300
Query: 329 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 388
RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK
Sbjct: 301 RLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPK 360
Query: 389 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 432
KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
Sbjct: 361 KLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 404
>gi|21361647 S-adenosylhomocysteine hydrolase-like 1 [Homo sapiens]
Length = 530
Score = 444 bits (1143), Expect = e-125
Identities = 217/425 (51%), Positives = 303/425 (71%), Gaps = 2/425 (0%)
Query: 9 VADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLV 68
V +I A +GR+ ++IAE +M L+ +R+R KPL GA+I GC H+T +TAVLIETL
Sbjct: 107 VKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLC 166
Query: 69 TLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMI 128
LGA+ +WS+CNI+STQ+ AAA+A+AG+ V+AWKGE+++++ WCI++ + NMI
Sbjct: 167 ALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMI 226
Query: 129 LDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSK 188
LDDGGDLT+ ++ KYP + IRGI EE+ TGVH LY++ G L VPA+NVNDSVTK K
Sbjct: 227 LDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQK 286
Query: 189 FDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 248
FDNLY CRES++DG+KR TDVM GK VV GYG+VGKGC AL+ GA V ITEIDPI
Sbjct: 287 FDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPIC 346
Query: 249 ALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDV 308
ALQA M+G+ V ++E ++ ++ +T TG +++ H ++MK+ IVCN+GH + EIDV
Sbjct: 347 ALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDV 406
Query: 309 KWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMA 368
L + ++ QVD +G+R++LLAEGRL+NL C+ P+FV+S + T Q +A
Sbjct: 407 TSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCST-VPTFVLSITATTQALA 465
Query: 369 QIELWTHPD-KYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKP 427
IEL+ P+ +Y V+ LPKK+DE VA HL + LT+LT+ QA+YLG++ +GPFKP
Sbjct: 466 LIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKP 525
Query: 428 DHYRY 432
++YRY
Sbjct: 526 NYYRY 530
>gi|195539349 S-adenosylhomocysteine hydrolase-like 2 isoform d
[Homo sapiens]
Length = 508
Score = 442 bits (1136), Expect = e-124
Identities = 215/425 (50%), Positives = 305/425 (71%), Gaps = 2/425 (0%)
Query: 9 VADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLV 68
V +I A +GR+ ++IAE EMP LM +R+R KPL GA+I GC H+T +TAVL+ETL
Sbjct: 85 VKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLG 144
Query: 69 TLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMI 128
LGA+ +W++CNI+ST + AAA+A++G PV+AWKGE+++++ WCI++ + + NMI
Sbjct: 145 ALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMI 204
Query: 129 LDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSK 188
LDDGGDLT+ I+ KYP + I+GI EE+ TGVH LY++ G L VPA+NVNDSVTK K
Sbjct: 205 LDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQK 264
Query: 189 FDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 248
FDNLY CRES++DG+KR TD+M GK VV GYG+VGKGC AL+ G+ V +TEIDPI
Sbjct: 265 FDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPIC 324
Query: 249 ALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDV 308
ALQA M+G+ + ++E ++ +I +T TG +++ H ++MK+ IVCN+GH + EIDV
Sbjct: 325 ALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDV 384
Query: 309 KWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMA 368
L + ++ QVD +G+RI+LLAEGRL+NL C+ P+FV+S + T Q +A
Sbjct: 385 ASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALA 443
Query: 369 QIELWTHPD-KYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKP 427
IEL+ P+ +Y V+ LPKK+DE VA HL + LT+LT++QA+YLG++ +GPFKP
Sbjct: 444 LIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKP 503
Query: 428 DHYRY 432
++YRY
Sbjct: 504 NYYRY 508
>gi|195539347 S-adenosylhomocysteine hydrolase-like 2 isoform c
[Homo sapiens]
Length = 509
Score = 442 bits (1136), Expect = e-124
Identities = 215/425 (50%), Positives = 305/425 (71%), Gaps = 2/425 (0%)
Query: 9 VADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLV 68
V +I A +GR+ ++IAE EMP LM +R+R KPL GA+I GC H+T +TAVL+ETL
Sbjct: 86 VKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLG 145
Query: 69 TLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMI 128
LGA+ +W++CNI+ST + AAA+A++G PV+AWKGE+++++ WCI++ + + NMI
Sbjct: 146 ALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMI 205
Query: 129 LDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSK 188
LDDGGDLT+ I+ KYP + I+GI EE+ TGVH LY++ G L VPA+NVNDSVTK K
Sbjct: 206 LDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQK 265
Query: 189 FDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 248
FDNLY CRES++DG+KR TD+M GK VV GYG+VGKGC AL+ G+ V +TEIDPI
Sbjct: 266 FDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPIC 325
Query: 249 ALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDV 308
ALQA M+G+ + ++E ++ +I +T TG +++ H ++MK+ IVCN+GH + EIDV
Sbjct: 326 ALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDV 385
Query: 309 KWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMA 368
L + ++ QVD +G+RI+LLAEGRL+NL C+ P+FV+S + T Q +A
Sbjct: 386 ASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALA 444
Query: 369 QIELWTHPD-KYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKP 427
IEL+ P+ +Y V+ LPKK+DE VA HL + LT+LT++QA+YLG++ +GPFKP
Sbjct: 445 LIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKP 504
Query: 428 DHYRY 432
++YRY
Sbjct: 505 NYYRY 509
>gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b
[Homo sapiens]
Length = 610
Score = 442 bits (1136), Expect = e-124
Identities = 215/425 (50%), Positives = 305/425 (71%), Gaps = 2/425 (0%)
Query: 9 VADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLV 68
V +I A +GR+ ++IAE EMP LM +R+R KPL GA+I GC H+T +TAVL+ETL
Sbjct: 187 VKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLG 246
Query: 69 TLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMI 128
LGA+ +W++CNI+ST + AAA+A++G PV+AWKGE+++++ WCI++ + + NMI
Sbjct: 247 ALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMI 306
Query: 129 LDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSK 188
LDDGGDLT+ I+ KYP + I+GI EE+ TGVH LY++ G L VPA+NVNDSVTK K
Sbjct: 307 LDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQK 366
Query: 189 FDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 248
FDNLY CRES++DG+KR TD+M GK VV GYG+VGKGC AL+ G+ V +TEIDPI
Sbjct: 367 FDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPIC 426
Query: 249 ALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDV 308
ALQA M+G+ + ++E ++ +I +T TG +++ H ++MK+ IVCN+GH + EIDV
Sbjct: 427 ALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDV 486
Query: 309 KWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMA 368
L + ++ QVD +G+RI+LLAEGRL+NL C+ P+FV+S + T Q +A
Sbjct: 487 ASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALA 545
Query: 369 QIELWTHPD-KYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKP 427
IEL+ P+ +Y V+ LPKK+DE VA HL + LT+LT++QA+YLG++ +GPFKP
Sbjct: 546 LIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKP 605
Query: 428 DHYRY 432
++YRY
Sbjct: 606 NYYRY 610
>gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [Homo
sapiens]
Length = 611
Score = 442 bits (1136), Expect = e-124
Identities = 215/425 (50%), Positives = 305/425 (71%), Gaps = 2/425 (0%)
Query: 9 VADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLV 68
V +I A +GR+ ++IAE EMP LM +R+R KPL GA+I GC H+T +TAVL+ETL
Sbjct: 188 VKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLG 247
Query: 69 TLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMI 128
LGA+ +W++CNI+ST + AAA+A++G PV+AWKGE+++++ WCI++ + + NMI
Sbjct: 248 ALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMI 307
Query: 129 LDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSK 188
LDDGGDLT+ I+ KYP + I+GI EE+ TGVH LY++ G L VPA+NVNDSVTK K
Sbjct: 308 LDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQK 367
Query: 189 FDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPIN 248
FDNLY CRES++DG+KR TD+M GK VV GYG+VGKGC AL+ G+ V +TEIDPI
Sbjct: 368 FDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPIC 427
Query: 249 ALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDV 308
ALQA M+G+ + ++E ++ +I +T TG +++ H ++MK+ IVCN+GH + EIDV
Sbjct: 428 ALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDV 487
Query: 309 KWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMA 368
L + ++ QVD +G+RI+LLAEGRL+NL C+ P+FV+S + T Q +A
Sbjct: 488 ASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCST-VPTFVLSITATTQALA 546
Query: 369 QIELWTHPD-KYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKP 427
IEL+ P+ +Y V+ LPKK+DE VA HL + LT+LT++QA+YLG++ +GPFKP
Sbjct: 547 LIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKP 606
Query: 428 DHYRY 432
++YRY
Sbjct: 607 NYYRY 611
>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
sapiens]
Length = 270
Score = 36.2 bits (82), Expect = 0.059
Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 11/99 (11%)
Query: 206 ATDVMIAGKVAVVAGYG-DVGKGCAQALRGFGARVIITEIDPI--NALQAAMEGYEVTTM 262
AT AGKV VV G G +G G +A GARV+I + D AL+ + G V +
Sbjct: 2 ATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG-AVFIL 60
Query: 263 DEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGH 301
+ QE ++ + I R F ++ D +V N GH
Sbjct: 61 CDVTQEDDVKTLVSETI-----RRFGRL--DCVVNNAGH 92
>gi|186928839 retinol dehydrogenase 12 [Homo sapiens]
Length = 316
Score = 31.6 bits (70), Expect = 1.5
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 196 RESLIDGIKRATDVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAM 254
R+ G+ R T+V + GKV V+ G +GK A+ L GARV I D + AA
Sbjct: 23 RKFFAGGVCR-TNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAAS 81
Query: 255 E 255
E
Sbjct: 82 E 82
>gi|6912396 glyoxylate reductase/hydroxypyruvate reductase [Homo
sapiens]
Length = 328
Score = 31.2 bits (69), Expect = 1.9
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 218 VAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVT-- 274
+ G G +G+ A+ L+ FG R + T P A + V+T + A Q I V
Sbjct: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217
Query: 275 -TTGCIDIILGRHFEQMKDDAIVCNIGHFDV 304
T + F++MK+ A+ NI DV
Sbjct: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDV 248
>gi|229576906 F-box and WD repeat domain containing 12 isoform 3
[Homo sapiens]
Length = 445
Score = 30.8 bits (68), Expect = 2.5
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 20/77 (25%)
Query: 81 IFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIH 140
+++ QD A A+ P Y C+E L KDGP M+ D GD+
Sbjct: 153 VWNCQDRDALAVLPMPQPCY------------CMEAYLT-KDGPFLMVGDAAGDI----- 194
Query: 141 TKYPQLLPGIRGISEET 157
Y LPG+R +S+ T
Sbjct: 195 --YTFTLPGLRDVSKVT 209
>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
[Homo sapiens]
Length = 464
Score = 30.8 bits (68), Expect = 2.5
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 20/77 (25%)
Query: 81 IFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIH 140
+++ QD A A+ P Y C+E L KDGP M+ D GD+
Sbjct: 172 VWNCQDRDALAVLPMPQPCY------------CMEAYLT-KDGPFLMVGDAAGDI----- 213
Query: 141 TKYPQLLPGIRGISEET 157
Y LPG+R +S+ T
Sbjct: 214 --YTFTLPGLRDVSKVT 228
>gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]
Length = 244
Score = 30.0 bits (66), Expect = 4.3
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 208 DVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVII---TEIDPINALQAAMEGYEVTTMD 263
++ +AG+ +V G G +G+G QAL GARV+ T+ D +++L G E +D
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD-LDSLVRECPGIEPVCVD 60
>gi|47157315 Janus kinase 3 [Homo sapiens]
Length = 1124
Score = 29.3 bits (64), Expect = 7.3
Identities = 19/66 (28%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 151 RGISEETTTGVH--NLYKMMANGILKVPAINV--NDSVTKSKFDNLY-GCRESLIDGIKR 205
RG S T++ V + Y++ K+PA ++ ++++ F +Y GCR ++DG R
Sbjct: 490 RGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEAR 549
Query: 206 ATDVMI 211
T+V++
Sbjct: 550 KTEVLL 555
>gi|13375746 hypothetical protein LOC79624 [Homo sapiens]
Length = 441
Score = 29.3 bits (64), Expect = 7.3
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 164 LYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLI 200
+Y+ + I++ P I+ D +SK N YG +ES+I
Sbjct: 120 MYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESII 156
>gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]
Length = 700
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 459 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 517
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 518 TMGNMFS 524
>gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]
Length = 702
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 461 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 519
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 520 TMGNMFS 526
>gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]
Length = 506
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 265 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 323
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 324 TMGNMFS 330
>gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]
Length = 506
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 265 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 323
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 324 TMGNMFS 330
>gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens]
Length = 703
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 462 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 520
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 521 TMGNMFS 527
>gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]
Length = 860
Score = 29.3 bits (64), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 17 WGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQW 76
WG + L + L + ER+ + I GC E A L+ + L AE++
Sbjct: 619 WGMELLTLPHGRQLRL-DLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG 677
Query: 77 SSCNIFS 83
+ N+FS
Sbjct: 678 TMGNMFS 684
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,363,312
Number of Sequences: 37866
Number of extensions: 629353
Number of successful extensions: 1208
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 21
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.