Search of human proteins with 9910460

Search of human proteins with 9910460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9910460 nitrilase family, member 2 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9910460 nitrilase family, member 2 [Homo sapiens]                  558   e-159
gi|5031947 nitrilase 1 [Homo sapiens]                                 185   3e-47
gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]                 52   7e-07
gi|17865816 vanin 2 isoform 2 [Homo sapiens]                           51   1e-06
gi|66932888 vanin 3 isoform 1 precursor [Homo sapiens]                 50   2e-06
gi|7706509 beta-ureidopropionase [Homo sapiens]                        50   3e-06
gi|223633991 vanin 1 precursor [Homo sapiens]                          42   4e-04
gi|4557373 biotinidase precursor [Homo sapiens]                        42   8e-04
gi|42734434 transmembrane protein 53 [Homo sapiens]                    33   0.35 
gi|63054868 YdjC homolog [Homo sapiens]                                32   0.79 
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]                     30   2.3  
gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]                     30   2.3  
gi|14042945 beta-amyloid binding protein precursor [Homo sapiens]      29   5.1  
gi|29244926 corin [Homo sapiens]                                       28   8.7  
gi|62243567 netrin receptor Unc5h1 [Homo sapiens]                      28   8.7  

>gi|9910460 nitrilase family, member 2 [Homo sapiens]
          Length = 276

 Score =  558 bits (1438), Expect = e-159
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MTSFRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPEYAEK 60
           MTSFRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPEYAEK
Sbjct: 1   MTSFRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPEYAEK 60

Query: 61  IPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDV 120
           IPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDV
Sbjct: 61  IPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDV 120

Query: 121 PGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFN 180
           PGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFN
Sbjct: 121 PGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFN 180

Query: 181 LTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEA 240
           LTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEA
Sbjct: 181 LTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEA 240

Query: 241 IVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP 276
           IVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP
Sbjct: 241 IVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP 276


>gi|5031947 nitrilase 1 [Homo sapiens]
          Length = 327

 Score =  185 bits (470), Expect = 3e-47
 Identities = 101/273 (36%), Positives = 154/273 (56%), Gaps = 11/273 (4%)

Query: 6   LALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPE---YAEKIP 62
           +A+ Q+  +  K  N       +REAA  GA +  LPE F+  + A+   E    +E + 
Sbjct: 49  VAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFD--FIARDPAETLHLSEPLG 106

Query: 63  GESTQKLSEVAKECSIYLIGGSIPE-----EDAGKLYNTCAVFGPDGTLLAKYRKIHLFD 117
           G+  ++ +++A+EC ++L  G   E     E   K+YN   +    G ++A YRK HL D
Sbjct: 107 GKLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCD 166

Query: 118 IDVPGKITFQESKTLSPGDSF-STFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYP 176
           +++PG+    ES +  PG S  S   TP  ++GL +CYDMRF EL+   AQ G ++L YP
Sbjct: 167 VEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYP 226

Query: 177 GAFNLTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAG 236
            AF   TGPAHWE+L R+RA++ Q YV  A+          ++GHS VV+PWG V+A+  
Sbjct: 227 SAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCS 286

Query: 237 TEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLY 269
               +  + IDL  L ++R+ +PVF+ +R DLY
Sbjct: 287 EGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 319


>gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]
          Length = 520

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 49/179 (27%)

Query: 15  SIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPE----YAEKIPGESTQ--- 67
           ++ ++N+    + I++AA QGA+I+  PE  ++ YG K+  E    Y E IP        
Sbjct: 52  NLMNENIDILETAIKQAAEQGARIIVTPE--DALYGWKFTRETVFPYLEDIPDPQVNWIP 109

Query: 68  --------------KLSEVAKECSIYLIGGSIPEEDAGKL-----------YNTCAVFGP 102
                         +LS +AK+ SIY++     ++                YNT  V+  
Sbjct: 110 CQDPHRFGHTPVQARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNT 169

Query: 103 DGTLLAKYRKIHLF---DIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRF 158
           +G L+A+Y K HL+     +VP K                TF+T + R G+  C+D+ F
Sbjct: 170 EGKLVARYHKYHLYSEPQFNVPEK------------PELVTFNTAFGRFGIFTCFDIFF 216


>gi|17865816 vanin 2 isoform 2 [Homo sapiens]
          Length = 467

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 49/176 (27%)

Query: 18  SDNVTRACSFIREAATQGAKIVSLPECFNSPYGAKYFPE----YAEKIPGESTQ------ 67
           ++N+    + I++AA QGA+I+  PE  ++ YG K+  E    Y E IP           
Sbjct: 2   NENIDILETAIKQAAEQGARIIVTPE--DALYGWKFTRETVFPYLEDIPDPQVNWIPCQD 59

Query: 68  -----------KLSEVAKECSIYLIGGSIPEEDAGKL-----------YNTCAVFGPDGT 105
                      +LS +AK+ SIY++     ++                YNT  V+  +G 
Sbjct: 60  PHRFGHTPVQARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGK 119

Query: 106 LLAKYRKIHLF---DIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRF 158
           L+A+Y K HL+     +VP K                TF+T + R G+  C+D+ F
Sbjct: 120 LVARYHKYHLYSEPQFNVPEK------------PELVTFNTAFGRFGIFTCFDIFF 163


>gi|66932888 vanin 3 isoform 1 precursor [Homo sapiens]
          Length = 274

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 50/161 (31%), Positives = 70/161 (43%), Gaps = 42/161 (26%)

Query: 28  IREAATQGAKIVSLPECFNSPYGAKYFPE----YAEKIPGEST----------------- 66
           ++ AA QGA I+  PE  +  YG  +  E    Y E IP                     
Sbjct: 65  VKLAAKQGAHIIVTPE--DGIYGWIFTRESIYPYLEDIPDPGVNWIPCRDPWRFGNTPVQ 122

Query: 67  QKLSEVAKECSIYL---IGGSIP--------EEDAGKLYNTCAVFGPDGTLLAKYRKIHL 115
           Q+LS +AK+ SIY+   IG   P          D    YNT  VF   G LLA+Y K +L
Sbjct: 123 QRLSCLAKDNSIYVVANIGDKKPCNASDSQCPPDGRYQYNTDVVFDSQGKLLARYHKYNL 182

Query: 116 FDIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDM 156
           F  ++  +  F +   L       TFDTP+ + G+  C+D+
Sbjct: 183 FAPEI--QFDFPKDSEL------VTFDTPFGKFGIFTCFDI 215


>gi|7706509 beta-ureidopropionase [Homo sapiens]
          Length = 384

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 14/189 (7%)

Query: 23  RACSFIREAATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKEC 76
           R  + +  AA  G  I+   E +  P+         + E+AE    G +T+   ++AK  
Sbjct: 99  RIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNH 158

Query: 77  SIYLIGGSIPE--EDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSP 134
            + ++   +    E    L+NT  V    G +L K RK H     +P    F ES     
Sbjct: 159 DMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNESTYYME 213

Query: 135 GD-SFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQR 193
           G+     F T + R+ + ICY         +Y+  G +++  P A       + W +  R
Sbjct: 214 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR 273

Query: 194 SRAVDNQVY 202
           + A+ N  +
Sbjct: 274 NAAIANHCF 282


>gi|223633991 vanin 1 precursor [Homo sapiens]
          Length = 513

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 48/167 (28%), Positives = 69/167 (41%), Gaps = 42/167 (25%)

Query: 28  IREAATQGAKIVSLPECFNSPYGAKYFPE----YAEKIPGEST----------------- 66
           I  AA QGA I+  PE  ++ YG  +  +    Y E IP                     
Sbjct: 64  ITSAADQGAHIIVTPE--DAIYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPVQ 121

Query: 67  QKLSEVAKECSIYLIGG---------SIPE--EDAGKLYNTCAVFGPDGTLLAKYRKIHL 115
           ++LS +AK  SIY++           S P+   D    YNT  VF   G L+A+Y K +L
Sbjct: 122 ERLSCLAKNNSIYVVANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNL 181

Query: 116 FDIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELA 162
           F     G+  F   K         TF+T +   G+  C+D+ F + A
Sbjct: 182 F----MGENQFNVPKE----PEIVTFNTTFGSFGIFTCFDILFHDPA 220


>gi|4557373 biotinidase precursor [Homo sapiens]
          Length = 543

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 17/97 (17%)

Query: 88  EDAGKLYNTCAVFGPDGTLLAKYRKIHLF---DIDVPGKITFQESKTLSPGDSFSTFDTP 144
           +D    +NT  VF  +GTL+ +YRK +L+     DVP K+               TFDTP
Sbjct: 188 KDGRYQFNTNVVFSNNGTLVDRYRKHNLYFEAAFDVPLKV------------DLITFDTP 235

Query: 145 YC-RVGLGICYDMRFAELA-QIYAQRGCQLLVYPGAF 179
           +  R G+  C+D+ F + A ++      + +VYP A+
Sbjct: 236 FAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAW 272


>gi|42734434 transmembrane protein 53 [Homo sapiens]
          Length = 277

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 116 FDIDVPGKITFQESKTLSPGDSFSTFDTPYC-RVGLGICYDMRFAELAQIYAQRGCQLLV 174
           + I++P +  + +  + SPG   +    P    +G G C D   A+ + IY +RGC ++ 
Sbjct: 8   YTIEIPDQPCWSQKNSPSPGGKEAETRQPVVILLGWGGCKDKNLAKYSAIYHKRGCIVIR 67

Query: 175 YPGAFNL 181
           Y   +++
Sbjct: 68  YTAPWHM 74


>gi|63054868 YdjC homolog [Homo sapiens]
          Length = 323

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 220 GHSTVVNPWGEVLAKAGTEEAIVYSDIDLKKL-AEIRQQIPVFRQ 263
           G S+++ P G  L K G  EA+   D+DL ++  E+  Q+  FR+
Sbjct: 78  GASSLLGPEGFFLGKMGFREAVAAGDVDLPQVREELEAQLSCFRE 122


>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
          Length = 586

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)

Query: 62  PGESTQKLSEVAKECS--IYLIGGSIPEEDAGKLYNTCAVFGP 102
           P   TQ+ S    E +  IY+ GGS+    +G++ N+C V+ P
Sbjct: 414 PSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDP 456


>gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]
          Length = 564

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)

Query: 62  PGESTQKLSEVAKECS--IYLIGGSIPEEDAGKLYNTCAVFGP 102
           P   TQ+ S    E +  IY+ GGS+    +G++ N+C V+ P
Sbjct: 392 PSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDP 434


>gi|14042945 beta-amyloid binding protein precursor [Homo sapiens]
          Length = 207

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 12/30 (40%), Positives = 15/30 (50%)

Query: 217 VAWGHSTVVNPWGEVLAKAGTEEAIVYSDI 246
           V W  S    PWG V   AG EE++   D+
Sbjct: 22  VLWFVSVTTGPWGAVATSAGGEESLKCEDL 51


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 4/41 (9%)

Query: 39  VSLPECFNSPYGAKYFPEYAEKIPGESTQKLSEVAKECSIY 79
           ++L  C N PY +  +P Y     G  TQK + ++ E S++
Sbjct: 458 ITLELCMNLPYNSTSYPNYF----GHRTQKEASISWESSLF 494


>gi|62243567 netrin receptor Unc5h1 [Homo sapiens]
          Length = 842

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 8/47 (17%)

Query: 135 GDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNL 181
           G SFS        +   I  D RFAEL  + ++ G   LV P AF +
Sbjct: 717 GQSFS--------INFNITKDTRFAELLALESEAGVPALVGPSAFKI 755


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,346,262
Number of Sequences: 37866
Number of extensions: 455209
Number of successful extensions: 831
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 16
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.