Search of human proteins with 94421458

Search of human proteins with 94421458

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        826   0.0  
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         788   0.0  
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         768   0.0  
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         725   0.0  
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         724   0.0  
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         724   0.0  
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         723   0.0  
gi|4503383 dopamine receptor D1 [Homo sapiens]                        214   8e-56
gi|4503391 dopamine receptor D5 [Homo sapiens]                        212   4e-55
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      206   4e-53
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           204   1e-52
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            204   1e-52
gi|21264324 trace amine associated receptor 1 [Homo sapiens]          201   1e-51
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                  198   6e-51
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa...   191   1e-48
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]   189   3e-48
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]   189   3e-48
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]    189   3e-48
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa...   189   5e-48
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                182   5e-46
gi|28173558 trace amine associated receptor 6 [Homo sapiens]          178   7e-45
gi|110618256 trace amine associated receptor 9 [Homo sapiens]         174   2e-43
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                172   5e-43
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...   170   2e-42
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    169   4e-42
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    169   4e-42
gi|16751917 trace amine associated receptor 8 [Homo sapiens]          169   5e-42
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]               166   3e-41
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa...   162   4e-40
gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap...   158   9e-39

>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  826 bits (2133), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
           FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360

Query: 361 STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT 402
           STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
Sbjct: 361 STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT 402


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  788 bits (2034), Expect = 0.0
 Identities = 388/402 (96%), Positives = 388/402 (96%), Gaps = 14/402 (3%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT 402
           STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
Sbjct: 347 STTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT 388


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  768 bits (1983), Expect = 0.0
 Identities = 388/442 (87%), Positives = 388/442 (87%), Gaps = 54/442 (12%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVLR----------------------------------------DAVECGG 380
           STTTINGSTHVLR                                        DAVECGG
Sbjct: 347 STTTINGSTHVLRTDFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGG 406

Query: 381 QWESQCHPPATSPLVAAQPSDT 402
           QWESQCHPPATSPLVAAQPSDT
Sbjct: 407 QWESQCHPPATSPLVAAQPSDT 428


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  725 bits (1871), Expect = 0.0
 Identities = 360/376 (95%), Positives = 360/376 (95%), Gaps = 14/376 (3%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVLRDAV 376
           STTTINGSTHVLR  V
Sbjct: 347 STTTINGSTHVLRYTV 362


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  724 bits (1870), Expect = 0.0
 Identities = 359/373 (96%), Positives = 359/373 (96%), Gaps = 14/373 (3%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVLR 373
           STTTINGSTHVLR
Sbjct: 347 STTTINGSTHVLR 359


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  724 bits (1870), Expect = 0.0
 Identities = 359/373 (96%), Positives = 359/373 (96%), Gaps = 14/373 (3%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVLR 373
           STTTINGSTHVLR
Sbjct: 347 STTTINGSTHVLR 359


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  723 bits (1865), Expect = 0.0
 Identities = 358/372 (96%), Positives = 358/372 (96%), Gaps = 14/372 (3%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226

Query: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346

Query: 361 STTTINGSTHVL 372
           STTTINGSTHVL
Sbjct: 347 STTTINGSTHVL 358


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score =  214 bits (546), Expect = 8e-56
 Identities = 130/363 (35%), Positives = 195/363 (53%), Gaps = 46/363 (12%)

Query: 7   NVSSEEGFGSVE------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           N S+ +G G V       +++   FLS +IL  +LGN LV  AV   R LR   TN+F++
Sbjct: 5   NTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVI 64

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLA +DLLV+VLVMP+ A+  +   W +G  FC +  + D++ +TASI +LC IS+DRY+
Sbjct: 65  SLAVSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYW 123

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
           AI   P  Y  KMTP    +++   W +   ISF+P+   W+                 D
Sbjct: 124 AI-SSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWH---------KAKPTSPSD 173

Query: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
            +A    +   N +S+     +++ YAI+ SV++FYIP  +M++ Y RIY  A++   +I
Sbjct: 174 GNATSLAETIDNCDSS-----LSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRI 228

Query: 241 QMLQRAGASSE--------------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCW 286
             L+RA   ++              S+P+S+ + S  R   ETK  KTL +IMG F  CW
Sbjct: 229 AALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKR---ETKVLKTLSVIMGVFVCCW 285

Query: 287 APFFVTNIVDPFI------DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLII 340
            PFF+ N + PF        + +    +  F+W G+ NS LNP +YAF N  FR+AF  +
Sbjct: 286 LPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAF-NADFRKAFSTL 344

Query: 341 LCC 343
           L C
Sbjct: 345 LGC 347


>gi|4503391 dopamine receptor D5 [Homo sapiens]
          Length = 477

 Score =  212 bits (540), Expect = 4e-55
 Identities = 129/352 (36%), Positives = 192/352 (54%), Gaps = 27/352 (7%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           +VV    L+ +I+  +LGN+LV  A+   R LR   TN FIVSLA +DL V++LVMP+ A
Sbjct: 40  QVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKA 99

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           +  V   W +G  FC V  + D++ +TASI +LC IS+DRY+AI  +P  Y+ KMT    
Sbjct: 100 VAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAI-SRPFRYKRKMTQRMA 157

Query: 139 ALMLGGCWVIPTFISFLPIMQGWN-----NIGIIDLERSLNQGLGQDFHAIEKRKFNQNS 193
            +M+G  W +   ISF+P+   W+     + G +DL  +L      ++   E+  +  + 
Sbjct: 158 LVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNL-----ANWTPWEEDFWEPDV 212

Query: 194 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 253
           N+  C   +N+ YAI+ S+++FYIP  +M++ Y RIY  A+    +I  L+RA   ++S 
Sbjct: 213 NAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSC 272

Query: 254 PQSA----DQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG---- 305
             SA    D      ++ ETK  KTL +IMG F  CW PFF+ N + PF      G    
Sbjct: 273 RSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAG 332

Query: 306 ------QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRP 351
                   +  F+W G+ NS LNP +YAF N  F++ F  +L C     R P
Sbjct: 333 FPCVSETTFDVFVWFGWANSSLNPVIYAF-NADFQKVFAQLLGCSHFCSRTP 383


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  206 bits (523), Expect = 4e-53
 Identities = 116/324 (35%), Positives = 172/324 (53%), Gaps = 29/324 (8%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           +S ++L  + GN+LV+ A+    +L+ + TNYFI SLA ADL++ + V+PFGA  ++  +
Sbjct: 40  MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W +G  +C   TS+DVL  TASI  LC I++DRY+AI   P  Y++ +T  +  +++   
Sbjct: 99  WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP 205
           W++    SFLPI   W                   + A  +   N  +N T C F  N+ 
Sbjct: 158 WIVSGLTSFLPIQMHW-------------------YRATHQEAINCYANETCCDFFTNQA 198

Query: 206 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM 265
           YAI  S+V+FY+P ++MV  Y R++  AK    +I   +             D  + H +
Sbjct: 199 YAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGL 258

Query: 266 R-------TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYIN 318
           R        E KA KTL IIMG F LCW PFF+ NIV    D  +  +V+    W+GY+N
Sbjct: 259 RRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVN 318

Query: 319 SGLNPFLYAFLNKSFRRAFLIILC 342
           SG NP +Y   +  FR AF  +LC
Sbjct: 319 SGFNPLIYC-RSPDFRIAFQELLC 341


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  204 bits (518), Expect = 1e-52
 Identities = 125/326 (38%), Positives = 179/326 (54%), Gaps = 39/326 (11%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           K+ +   L+ +IL+ + GN++V +AV  +R+LR + TN FIVSLA  DLL+ +LV+PF A
Sbjct: 18  KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  +   W +G+VFC + TSLDV+L TASI +L  ISLDRY A+   PL Y   +TP+R+
Sbjct: 77  IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198
           A+ L   WVI   +SFL I  GWN+          ++G               N  ++ C
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS------RNETSKG---------------NHTTSKC 174

Query: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSAD 258
              VN+ Y +   +V FY+P L+M + YYRI+  A++ A +I  +            S+ 
Sbjct: 175 KVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSW 222

Query: 259 QHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYI 317
           + +T R   E KA  TL  +MG F +CW P+F   +           +V  A  LWLGY 
Sbjct: 223 KAATIR---EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYA 279

Query: 318 NSGLNPFLYAFLNKSFRRAFLIILCC 343
           NS LNP LYA LN+ FR  +  + CC
Sbjct: 280 NSALNPILYAALNRDFRTGYQQLFCC 305


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  204 bits (518), Expect = 1e-52
 Identities = 125/326 (38%), Positives = 179/326 (54%), Gaps = 39/326 (11%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           K+ +   L+ +IL+ + GN++V +AV  +R+LR + TN FIVSLA  DLL+ +LV+PF A
Sbjct: 18  KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  +   W +G+VFC + TSLDV+L TASI +L  ISLDRY A+   PL Y   +TP+R+
Sbjct: 77  IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198
           A+ L   WVI   +SFL I  GWN+          ++G               N  ++ C
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS------RNETSKG---------------NHTTSKC 174

Query: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSAD 258
              VN+ Y +   +V FY+P L+M + YYRI+  A++ A +I  +            S+ 
Sbjct: 175 KVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSW 222

Query: 259 QHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYI 317
           + +T R   E KA  TL  +MG F +CW P+F   +           +V  A  LWLGY 
Sbjct: 223 KAATIR---EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYA 279

Query: 318 NSGLNPFLYAFLNKSFRRAFLIILCC 343
           NS LNP LYA LN+ FR  +  + CC
Sbjct: 280 NSALNPILYAALNRDFRTGYQQLFCC 305


>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
          Length = 339

 Score =  201 bits (510), Expect = 1e-51
 Identities = 113/320 (35%), Positives = 172/320 (53%), Gaps = 26/320 (8%)

Query: 22  LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
           L + +  +IL  ++GNL+V+V++   +QL    TN+ I S+A  D L+  LVMP+  +  
Sbjct: 26  LYSLMVLIILTTLVGNLIVIVSISHFKQLHT-PTNWLIHSMATVDFLLGCLVMPYSMVRS 84

Query: 82  VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
            +  W +GEVFC + TS D++L++ASIFHL  IS+DRYYA+C  PL Y+ KM  L I +M
Sbjct: 85  AEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVC-DPLRYKAKMNILVICVM 143

Query: 142 LGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFM 201
           +   W +P   +F          G+I LE +        F   E+  +        C   
Sbjct: 144 IFISWSVPAVFAF----------GMIFLELN--------FKGAEEIYYKHVHCRGGCSVF 185

Query: 202 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 261
            +K   +   + +FYIP  +M+  YYRIY+ AKE A  I        +++      +  +
Sbjct: 186 FSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLIS------DANQKLQIGLEMKN 239

Query: 262 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGL 321
                 E KA KTL I+MG F +CW PFF+  ++DPF+ Y +P  +    +W GY+NS  
Sbjct: 240 GISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTF 299

Query: 322 NPFLYAFLNKSFRRAFLIIL 341
           NP +YAF    FR+A  ++L
Sbjct: 300 NPMVYAFFYPWFRKALKMML 319


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score =  198 bits (504), Expect = 6e-51
 Identities = 126/358 (35%), Positives = 179/358 (50%), Gaps = 55/358 (15%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           ++ ++L+ + GN+LV+VA+    +L+ + TN FI+SLA ADL++ +LV+PFGA  +V   
Sbjct: 65  MALIVLLIVAGNVLVIVAIAKTPRLQTL-TNLFIMSLASADLVMGLLVVPFGATIVVWGR 123

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W YG  FC + TS+DVL  TASI  LC I+LDRY AI   P  Y++ +T  R   ++   
Sbjct: 124 WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAI-TSPFRYQSLLTRARARGLVCTV 182

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP 205
           W I   +SFLPI+  W      +  R  N                   +   C F+ N+ 
Sbjct: 183 WAISALVSFLPILMHWWRAESDEARRCYN-------------------DPKCCDFVTNRA 223

Query: 206 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS--------- 256
           YAI  SVV+FY+P  +M   Y R++  A++   +I   +R      +RP S         
Sbjct: 224 YAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAP 283

Query: 257 ----------------------ADQHSTHRM--RTETKAAKTLCIIMGCFCLCWAPFFVT 292
                                 A +    R+    E KA KTL IIMG F LCW PFF+ 
Sbjct: 284 APPPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLA 343

Query: 293 NIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 350
           N+V  F    VP +++  F WLGY NS  NP +Y   +  FR+AF  +LCC     RR
Sbjct: 344 NVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYC-RSPDFRKAFQGLLCCARRAARR 400


>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
           sapiens]
          Length = 351

 Score =  191 bits (485), Expect = 1e-48
 Identities = 106/323 (32%), Positives = 174/323 (53%), Gaps = 35/323 (10%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198
             +L  CW +P   +F          G++  E   +   G D            + S+ C
Sbjct: 161 KRLLLLCWSVPGAFAF----------GVVFSEAYADGIEGYDILV---------ACSSSC 201

Query: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSAD 258
             M NK +  T  +  F+ P  +MV  Y +I+  +++HAH I  L+              
Sbjct: 202 PVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR-------------- 247

Query: 259 QHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYIN 318
           ++  ++++ + KAAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY N
Sbjct: 248 ENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFN 307

Query: 319 SGLNPFLYAFLNKSFRRAFLIIL 341
           S  NP +Y F    FRRA   IL
Sbjct: 308 STCNPLIYGFFYPWFRRALKYIL 330


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score =  189 bits (481), Expect = 3e-48
 Identities = 129/364 (35%), Positives = 184/364 (50%), Gaps = 58/364 (15%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI-TRPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQN 192
                +A M+   W++   I+ LP + GW                             QN
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGW----------------------------AQN 224

Query: 193 SN-STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGAS 249
            N    C+   +  Y I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    
Sbjct: 225 VNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPD 284

Query: 250 SE-------------------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFF 290
           S                    SR    ++ +    + E KAA TL II+G F +CW PFF
Sbjct: 285 SVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFF 344

Query: 291 VTNIVDPFIDYT----VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDE 346
           + +   PFI  T    +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C   
Sbjct: 345 LLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR 404

Query: 347 RYRR 350
              R
Sbjct: 405 NINR 408


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score =  189 bits (481), Expect = 3e-48
 Identities = 129/364 (35%), Positives = 184/364 (50%), Gaps = 58/364 (15%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI-TRPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQN 192
                +A M+   W++   I+ LP + GW                             QN
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGW----------------------------AQN 224

Query: 193 SN-STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGAS 249
            N    C+   +  Y I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    
Sbjct: 225 VNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPD 284

Query: 250 SE-------------------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFF 290
           S                    SR    ++ +    + E KAA TL II+G F +CW PFF
Sbjct: 285 SVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFF 344

Query: 291 VTNIVDPFIDYT----VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDE 346
           + +   PFI  T    +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C   
Sbjct: 345 LLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR 404

Query: 347 RYRR 350
              R
Sbjct: 405 NINR 408


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score =  189 bits (481), Expect = 3e-48
 Identities = 129/364 (35%), Positives = 184/364 (50%), Gaps = 58/364 (15%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI-TRPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQN 192
                +A M+   W++   I+ LP + GW                             QN
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGW----------------------------AQN 224

Query: 193 SN-STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGAS 249
            N    C+   +  Y I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    
Sbjct: 225 VNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPD 284

Query: 250 SE-------------------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFF 290
           S                    SR    ++ +    + E KAA TL II+G F +CW PFF
Sbjct: 285 SVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFF 344

Query: 291 VTNIVDPFIDYT----VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDE 346
           + +   PFI  T    +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C   
Sbjct: 345 LLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYR 404

Query: 347 RYRR 350
              R
Sbjct: 405 NINR 408


>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
           sapiens]
          Length = 306

 Score =  189 bits (479), Expect = 5e-48
 Identities = 105/320 (32%), Positives = 172/320 (53%), Gaps = 35/320 (10%)

Query: 22  LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
           + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  I  
Sbjct: 1   MYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSMIRS 59

Query: 82  VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
           V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I  +
Sbjct: 60  VENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVIKRL 118

Query: 142 LGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFM 201
           L  CW +P   +F          G++  E   +   G D            + S+ C  M
Sbjct: 119 LLLCWSVPGAFAF----------GVVFSEAYADGIEGYDILV---------ACSSSCPVM 159

Query: 202 VNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHS 261
            NK +  T  +  F+ P  +MV  Y +I+  +++HAH I  L+              ++ 
Sbjct: 160 FNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQ 205

Query: 262 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGL 321
            ++++ + KAAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  
Sbjct: 206 NNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTC 265

Query: 322 NPFLYAFLNKSFRRAFLIIL 341
           NP +Y F    FRRA   IL
Sbjct: 266 NPLIYGFFYPWFRRALKYIL 285


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  182 bits (462), Expect = 5e-46
 Identities = 124/363 (34%), Positives = 176/363 (48%), Gaps = 57/363 (15%)

Query: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
           S + V +  FL+  ILMA+ GNLLV+++V  +R L+ + TNYFIV+LA ADLL+S  V+P
Sbjct: 93  SAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTV-TNYFIVNLAVADLLLSATVLP 151

Query: 76  FGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTP 135
           F A   V   W +G  FC V  ++DVL  TASI  LC IS+DRY  +    L Y   MT 
Sbjct: 152 FSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGV-RHSLKYPAIMTE 210

Query: 136 LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNS 195
            + A +L   WV+   +S  P++ GW                          K     + 
Sbjct: 211 RKAAAILALLWVVALVVSVGPLL-GW--------------------------KEPVPPDE 243

Query: 196 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE-- 251
            +C       YA+  SV +FY+P  ++V+ Y R+YV A+     ++  + +  G +SE  
Sbjct: 244 RFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVV 303

Query: 252 ----SRPQSADQHSTHRMRT-------------------ETKAAKTLCIIMGCFCLCWAP 288
                R  +      H MR+                   E KAAKTL I++G F LCW P
Sbjct: 304 LRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFP 363

Query: 289 FFVTNIVDPFIDYTVPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDER 347
           FF    +        P + V+    WLGY NS +NP +Y   ++ F+RAFL +L C   R
Sbjct: 364 FFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRR 423

Query: 348 YRR 350
            RR
Sbjct: 424 RRR 426


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score =  178 bits (452), Expect = 7e-45
 Identities = 108/353 (30%), Positives = 174/353 (49%), Gaps = 40/353 (11%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           F    +V+L        ++A+ GNLLVM+++   +QL    TN+ + SLA AD LV V V
Sbjct: 27  FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85

Query: 74  MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
           MPF  +  V+  W +G  FC   T  DV    +S+FHLC IS+DRY A+   PLVY  K 
Sbjct: 86  MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144

Query: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNS 193
           T     + +   W++P   S      G  + G+ +L  +LN   G               
Sbjct: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG--------------- 189

Query: 194 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 253
               C  +VN+ + +T   ++F+IP  +M++ Y  I++ A+  A +I   +  G+ +ES 
Sbjct: 190 ----CQTVVNQNWVLT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES- 240

Query: 254 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLW 313
             S++ +     R E KAAKTL + +  F + W P+ + +++D F+ +  P  ++    W
Sbjct: 241 --SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCW 298

Query: 314 LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 366
             Y NS +NP +YA     FR+A  +I            + GQ +  S+ T+N
Sbjct: 299 CAYYNSAMNPLIYALFYPWFRKAIKVI------------VTGQVLKNSSATMN 339


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score =  174 bits (440), Expect = 2e-43
 Identities = 108/322 (33%), Positives = 162/322 (50%), Gaps = 30/322 (9%)

Query: 21  VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
           +L   L    ++A  GNLLVM+A+   +QL    TN+ I SLA AD LV V VMPF  + 
Sbjct: 34  ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92

Query: 81  LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
            V+  W +G+ +C   T  D     AS+FHLCCIS+DRY A+   PL Y  K T     +
Sbjct: 93  SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151

Query: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVF 200
            +   W      SF     G N  GI +L  +L    G                   C  
Sbjct: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-------------------CQA 192

Query: 201 MVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQH 260
            +N+ + + C ++ F+IP + MV  Y +I++ AK  A +I+       S+ S+ QS+ + 
Sbjct: 193 PLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSES 244

Query: 261 STHRM-RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINS 319
              R+ + E KAAKTL I M  F + W P+ V  ++D ++++  P  V+   +W  Y NS
Sbjct: 245 YKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNS 304

Query: 320 GLNPFLYAFLNKSFRRAFLIIL 341
            +NP +YAF  + F +A  +I+
Sbjct: 305 AMNPLIYAFFYQWFGKAIKLIV 326


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  172 bits (436), Expect = 5e-43
 Identities = 117/343 (34%), Positives = 166/343 (48%), Gaps = 54/343 (15%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           L   IL AI+GN+LV+++V  +R LR   TNYFIV+LA ADLL+S  V+PF A   V   
Sbjct: 52  LGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALEVLGY 110

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W+ G +FC +  ++DVL  TASI  LC IS+DRY  +    L Y   +T  +  L L   
Sbjct: 111 WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV-RYSLQYPTLVTRRKAILALLSV 169

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP 205
           WV+ T IS  P++ GW                          K    ++   C       
Sbjct: 170 WVLSTVISIGPLL-GW--------------------------KEPAPNDDKECGVTEEPF 202

Query: 206 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE------------ 251
           YA+  S+ +FYIP  ++++ Y R+Y+ AK     ++  +++    S E            
Sbjct: 203 YALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHE 262

Query: 252 ----------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT-NIVDPFID 300
                       P+S+      +   E KAAKTL I++G F LCW PFF+   +   F  
Sbjct: 263 DTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFST 322

Query: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC 343
              P  V+    WLGY NS LNP +Y   +K F+RAF+ IL C
Sbjct: 323 LKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGC 365


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score =  170 bits (430), Expect = 2e-42
 Identities = 110/331 (33%), Positives = 163/331 (49%), Gaps = 39/331 (11%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           L  VI +    N L++  +C    LR   +N+F+VSL  +DL+V ++VMP   +  +   
Sbjct: 33  LCVVIALTAAANSLLIALICTQPALRNT-SNFFLVSLFTSDLMVGLVVMPPAMLNALYGR 91

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W+     CL+ T+ DV+  +ASI +LC ISLDRY  I   PL Y+ +MTPLR   ++ G 
Sbjct: 92  WVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLIL-SPLRYKLRMTPLRALALVLGA 150

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP 205
           W +    SFLP++ GW+ +G                HA       +      C  + + P
Sbjct: 151 WSLAALASFLPLLLGWHELG----------------HA-------RPPVPGQCRLLASLP 187

Query: 206 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES---------RP-- 254
           + +  S + F++P   +   Y RI + A++ A Q+  L    AS  S         RP  
Sbjct: 188 FVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGV 247

Query: 255 QSADQH--STHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL 312
           +SAD    +T   R   KA+ TL I++G F + W PFFV NIV    D   PG ++    
Sbjct: 248 ESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLT 306

Query: 313 WLGYINSGLNPFLYAFLNKSFRRAFLIILCC 343
           WLGY NS +NP +Y    + F+RA    L C
Sbjct: 307 WLGYCNSTMNPIIYPLFMRDFKRALGRFLPC 337


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  169 bits (428), Expect = 4e-42
 Identities = 111/349 (31%), Positives = 170/349 (48%), Gaps = 52/349 (14%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSN 194
             R  + L   W +   IS  P+  GW      D                          
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED-------------------------- 172

Query: 195 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ------------- 241
            T C       Y +  ++ +FY+P  ++++ Y R+YV AK  +  ++             
Sbjct: 173 ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQV 232

Query: 242 --MLQRAGASSESRPQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTN 293
              + R  A +     ++ +  TH      +   E KAAKTL I++GCF LCW PFF+  
Sbjct: 233 TLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVM 292

Query: 294 IVDPFI-DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 341
            +  F  D+     V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 293 PIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  169 bits (428), Expect = 4e-42
 Identities = 111/349 (31%), Positives = 170/349 (48%), Gaps = 52/349 (14%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSN 194
             R  + L   W +   IS  P+  GW      D                          
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED-------------------------- 172

Query: 195 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ------------- 241
            T C       Y +  ++ +FY+P  ++++ Y R+YV AK  +  ++             
Sbjct: 173 ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQV 232

Query: 242 --MLQRAGASSESRPQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTN 293
              + R  A +     ++ +  TH      +   E KAAKTL I++GCF LCW PFF+  
Sbjct: 233 TLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVM 292

Query: 294 IVDPFI-DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 341
            +  F  D+     V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 293 PIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
          Length = 342

 Score =  169 bits (427), Expect = 5e-42
 Identities = 104/334 (31%), Positives = 164/334 (49%), Gaps = 28/334 (8%)

Query: 11  EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70
           E  +    +V+L T  S   L+A+ GNLLVM +V   +QL    TN+ I SLA AD LV 
Sbjct: 23  ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81

Query: 71  VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
           V VM F  +  V+  W +G  FC + +  DV    +S+ HLC I +DRY  +   PLVY 
Sbjct: 82  VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140

Query: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFN 190
            K T     + +   W++P   S      G N+ G+ +L  +LN   G            
Sbjct: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG------------ 188

Query: 191 QNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASS 250
                  C  +V++ + +    + F+IP L+M++ Y +I++ AK+ A +I+       +S
Sbjct: 189 -------CQIIVSQGW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTS 234

Query: 251 ESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA 310
                S++ +     + E KAAKTL + +  F + W P+ V  ++D F+ +  P  ++  
Sbjct: 235 SKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEI 294

Query: 311 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCD 344
             W  Y NS +NP +YA     FR+A  +IL  D
Sbjct: 295 CCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGD 328


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score =  166 bits (420), Expect = 3e-41
 Identities = 128/394 (32%), Positives = 184/394 (46%), Gaps = 56/394 (14%)

Query: 4   LDANVSSEEGFGSV--EKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVS 61
           L  N ++  G   V  E  +    L+  +L  + GNLLV+VA+ W  +L+ + TN F+ S
Sbjct: 20  LAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTM-TNVFVTS 78

Query: 62  LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121
           LA ADL++ +LV+P  A   +   W  G   C + TS+DVL  TASI  LC +++DRY A
Sbjct: 79  LAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLA 138

Query: 122 ICCQPLVYRNKMTP--LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQ 179
           +   PL Y   +T    R A++L   WV+   +SF PIM  W  +G  D E        Q
Sbjct: 139 V-TNPLRYGALVTKRCARTAVVL--VWVVSAAVSFAPIMSQWWRVG-ADAE-------AQ 187

Query: 180 DFHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQ 239
             H          SN   C F  N PY +  S V+FY+P L+M+  Y R++V A      
Sbjct: 188 RCH----------SNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRL 237

Query: 240 IQMLQRAGASSESRPQSADQHSTHRMRT---------------------ETKAAKTLCII 278
           ++         ES P  +   +   + T                     E +A  TL +I
Sbjct: 238 LRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLI 297

Query: 279 MGCFCLCWAPFFVTNIVDPFIDYT-VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAF 337
           MG F LCW PFF+ N++      + VPG  + A  WLGY NS  NP +Y   +  FR AF
Sbjct: 298 MGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYC-RSPDFRSAF 356

Query: 338 LIILCCDDERY-------RRPSILGQTVPCSTTT 364
             +LC    R         RP++    VP + ++
Sbjct: 357 RRLLCRCGRRLPPEPCAAARPALFPSGVPAARSS 390


>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
           sapiens]
          Length = 366

 Score =  162 bits (411), Expect = 4e-40
 Identities = 122/390 (31%), Positives = 179/390 (45%), Gaps = 76/390 (19%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTF-LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFI 59
           ++  D N++SEE    +   +L++  LS + LM    N LV+ A+   R+L     NY I
Sbjct: 4   LNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHH-PANYLI 62

Query: 60  VSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRY 119
            SLA  D LV+VLVMPF  + +V++ WI G+V C +  S+D+   T SI HL  I+LDRY
Sbjct: 63  CSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRY 122

Query: 120 YAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQ 179
            AI    + Y  K TP    +M+   W+I  FIS  P+   W            +QG  +
Sbjct: 123 RAI-TDAVEYARKRTPKHAGIMITIVWIISVFISMPPLF--WR-----------HQGTSR 168

Query: 180 DFHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKE--HA 237
           D   I K   +   ++ Y  F             AFYIP  L+++ YY+IY  AK   H 
Sbjct: 169 DDECIIKH--DHIVSTIYSTF------------GAFYIPLALILILYYKIYRAAKTLYHK 214

Query: 238 HQIQMLQRAGASSESRPQSADQ-------------------------HSTHRM------- 265
            Q   + +   + +   +S ++                         HST R        
Sbjct: 215 RQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKH 274

Query: 266 -----------RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL-W 313
                        E KAA TL +I+G F +CW PFFV  +V    D     +  + FL W
Sbjct: 275 EKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAW 334

Query: 314 LGYINSGLNPFLYAFLNKSFRRAFLIILCC 343
           LGY+NS +NP +Y   N+ F++AF  ++ C
Sbjct: 335 LGYLNSLINPLIYTIFNEDFKKAFQKLVRC 364


>gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo
           sapiens]
          Length = 458

 Score =  158 bits (399), Expect = 9e-39
 Identities = 117/362 (32%), Positives = 182/362 (50%), Gaps = 66/362 (18%)

Query: 29  VILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQD-IWI 87
           +I+M I GN+LV++AV  +++L    TNYF++SLA AD+LV +LVMP   + ++ D +W 
Sbjct: 63  IIIMTIGGNILVIMAVSMEKKLHNA-TNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWP 121

Query: 88  YGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWV 147
                C V  SLDVL +TASI HLC ISLDRY AI   P+ +    +  +  + +   W 
Sbjct: 122 LPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAI-RNPIEHSRFNSRTKAIMKIAIVWA 180

Query: 148 IPTFISF-LPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP- 205
           I   +S  +P+      IG+ D E+                      N+T CV  +N P 
Sbjct: 181 ISIGVSVPIPV------IGLRDEEKVF-------------------VNNTTCV--LNDPN 213

Query: 206 YAITCSVVAFYIPFLLMVLAY-YRIYVTAKE-----HAHQ----------IQMLQRAGAS 249
           + +  S VAF+IP  +MV+ Y   IYV  ++     H H           ++  +R  A 
Sbjct: 214 FVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAE 273

Query: 250 SE-SRPQSADQHSTHR-------------MRTETKAAKTLCIIMGCFCLCWAPFFVTNIV 295
            E S   + DQ++  R             +  E KA+K L I+   F + W PFF+TNI+
Sbjct: 274 EENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNIL 333

Query: 296 DPFIDYT----VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRP 351
               + +    +  ++   F+W+GY+ SG+NP +Y   NK +RRAF   L C+ +  ++P
Sbjct: 334 SVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKP 393

Query: 352 SI 353
            +
Sbjct: 394 PV 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,203,960
Number of Sequences: 37866
Number of extensions: 583902
Number of successful extensions: 3730
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 2209
Number of HSP's gapped (non-prelim): 1147
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.