Guide to the Human Genome
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Search of human proteins with 91807125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91807125 family with sequence similarity 3, member C
precursor [Homo sapiens]
         (227 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91807125 family with sequence similarity 3, member C precurso...   461   e-130
gi|7661714 family with sequence similarity 3, member C precursor...   461   e-130
gi|13324682 family 3, member A protein [Homo sapiens]                 243   7e-65
gi|20270363 family with sequence similarity 3, member D [Homo sa...   239   1e-63
gi|46255030 family with sequence similarity 3, member B isoform ...   149   1e-36
gi|46255032 family with sequence similarity 3, member B isoform ...   147   6e-36
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    62   4e-10
gi|38638698 KIAA1199 [Homo sapiens]                                    59   3e-09
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]          42   6e-04
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]            42   6e-04
gi|4557233 short-chain acyl-CoA dehydrogenase precursor [Homo sa...    29   2.9  
gi|189011548 N-acylsphingosine amidohydrolase 1 isoform a prepro...    28   4.9  
gi|189011546 N-acylsphingosine amidohydrolase 1 isoform b [Homo ...    28   4.9  
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    28   4.9  
gi|82659091 staufen isoform c [Homo sapiens]                           28   8.4  

>gi|91807125 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  461 bits (1186), Expect = e-130
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60
           MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI
Sbjct: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60

Query: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
           SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK
Sbjct: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120

Query: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180
           YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD
Sbjct: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180

Query: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD 227
           NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD
Sbjct: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD 227


>gi|7661714 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  461 bits (1186), Expect = e-130
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60
           MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI
Sbjct: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60

Query: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
           SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK
Sbjct: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120

Query: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180
           YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD
Sbjct: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180

Query: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD 227
           NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD
Sbjct: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD 227


>gi|13324682 family 3, member A protein [Homo sapiens]
          Length = 230

 Score =  243 bits (621), Expect = 7e-65
 Identities = 118/231 (51%), Positives = 166/231 (71%), Gaps = 11/231 (4%)

Query: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFAR-SALDTAARS--TKPPR-- 55
           MR+AG  ++VV V    +T+ V+S +         G+ F R   L T+  S  T  PR  
Sbjct: 1   MRLAGPLRIVVLVVSVGVTWIVVSILL-----GGPGSGFPRIQQLFTSPESSVTAAPRAR 55

Query: 56  -YKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTG 114
            YKCG+ + CPE+H AF++ SGAANV+GPKICLED +LMS VK+NVGRG+N+AL NG +G
Sbjct: 56  KYKCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVSG 115

Query: 115 EVLDTKYFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSIT 174
           E+++ + FDMW GDV   ++F++ + +GT+V + +YDD ATK+N+E R+L ++LGS +  
Sbjct: 116 ELIEARAFDMWAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRNAK 175

Query: 175 NLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQK 225
            L FRD+WVF G KG++ KSPFEQH+KN+K +NKYEG PE +EMEGCIP++
Sbjct: 176 ELAFRDSWVFVGAKGVQNKSPFEQHVKNSKHSNKYEGCPEALEMEGCIPRR 226


>gi|20270363 family with sequence similarity 3, member D [Homo
           sapiens]
          Length = 224

 Score =  239 bits (610), Expect = 1e-63
 Identities = 114/225 (50%), Positives = 151/225 (67%), Gaps = 3/225 (1%)

Query: 1   MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60
           MRV+G  +L+  +   + T+  I       M         R    +  +  +  +YKCG+
Sbjct: 1   MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIR---LPRWLAASPTKEIQVKKYKCGL 57

Query: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
            K CP  +FAFK+ SGAANVVGP +C ED ++MS VKNNVGRG+N+AL NG TG VL  K
Sbjct: 58  IKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQK 117

Query: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180
            FDM+ GDV   ++FLK I  G +VL+ +YDD  TK+NDE+R+L +DLGS+    LGFRD
Sbjct: 118 AFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRD 177

Query: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQK 225
           +WVF G K ++ KSPFEQ +KN+ DTNKYEGWPE++EMEGC+P K
Sbjct: 178 SWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPK 222


>gi|46255030 family with sequence similarity 3, member B isoform a
           [Homo sapiens]
          Length = 235

 Score =  149 bits (377), Expect = 1e-36
 Identities = 85/229 (37%), Positives = 126/229 (55%), Gaps = 8/229 (3%)

Query: 5   GAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAAR----STKPPRYKCGI 60
           G  K+V  V   L  +Y    + E+  DA L +  A S      R    +  P R KC  
Sbjct: 7   GLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSA-AYSIRSIGERPVLKAPVPKRQKCDH 65

Query: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
              CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  TG V  T+
Sbjct: 66  WTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATR 125

Query: 121 YFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFR 179
            FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS  I N+ FR
Sbjct: 126 CFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFR 185

Query: 180 DNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226
            +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 186 SSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 234


>gi|46255032 family with sequence similarity 3, member B isoform b
           [Homo sapiens]
          Length = 187

 Score =  147 bits (372), Expect = 6e-36
 Identities = 72/177 (40%), Positives = 107/177 (60%), Gaps = 3/177 (1%)

Query: 53  PPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGK 112
           P R KC     CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  
Sbjct: 10  PKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYV 69

Query: 113 TGEVLDTKYFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGST 171
           TG V  T+ FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS 
Sbjct: 70  TGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSK 129

Query: 172 SITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226
            I N+ FR +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 130 EIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 186


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 8/146 (5%)

Query: 45  DTAARSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGI 104
           D A    +PPR +     + P +    ++ S  + V    + ++   ++       GRGI
Sbjct: 79  DEALGRLEPPRRR----GSGPRRVLDVEVYSSRSKVY---VAVDGTTVLEDEAREQGRGI 131

Query: 105 NVALANGKTGEVLDTKYFDMWGG-DVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARR 163
           +V + N  TG V+  + FD +   +    + FL  +  G +++    D+G+  L D A+ 
Sbjct: 132 HVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKA 191

Query: 164 LIADLGSTSITNLGFRDNWVFCGGKG 189
           L+  LGS +   LG+RD W F G KG
Sbjct: 192 LLRSLGSQAGPALGWRDTWAFVGRKG 217


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 3/102 (2%)

Query: 102 RGINVALANGKTGEVLDTKYFDMWGG--DVAPFIEFLKAIQDGTIVLMGTYDDGATKLND 159
           RG+ V + + K+G V+ +  FD +    +    +++L A+ DG I+ +   D+G+  L+D
Sbjct: 187 RGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDD 246

Query: 160 EARRLIADLGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIK 201
            AR+ +  LGS    +LGFR  W F   KG    S  E HI+
Sbjct: 247 MARKAMTKLGSKHFLHLGFRHPWSFLTVKG-NPSSSVEDHIE 287


>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
          Length = 1320

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319

Query: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352


>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
          Length = 1383

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319

Query: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352


>gi|4557233 short-chain acyl-CoA dehydrogenase precursor [Homo
           sapiens]
          Length = 412

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 4/53 (7%)

Query: 163 RLIADLGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEV 215
           +L A   +T+I++   +      GG G  T+ P E+H ++ + T  YEG  E+
Sbjct: 349 KLAASEAATAISHQAIQ----ILGGMGYVTEMPAERHYRDARITEIYEGTSEI 397


>gi|189011548 N-acylsphingosine amidohydrolase 1 isoform a
           preproprotein [Homo sapiens]
          Length = 395

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/65 (26%), Positives = 33/65 (50%)

Query: 84  KICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTKYFDMWGGDVAPFIEFLKAIQDGT 143
           ++ L+   ++  + N++   IN  + +GK  +V+D K   + G    PF E +K I   T
Sbjct: 64  ELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVT 123

Query: 144 IVLMG 148
            + +G
Sbjct: 124 DIPLG 128


>gi|189011546 N-acylsphingosine amidohydrolase 1 isoform b [Homo
           sapiens]
          Length = 411

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/65 (26%), Positives = 33/65 (50%)

Query: 84  KICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTKYFDMWGGDVAPFIEFLKAIQDGT 143
           ++ L+   ++  + N++   IN  + +GK  +V+D K   + G    PF E +K I   T
Sbjct: 80  ELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVT 139

Query: 144 IVLMG 148
            + +G
Sbjct: 140 DIPLG 144


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 76  GAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTKYF 122
           G     G K+C + +     VKN + +G + +  NGK GE +   YF
Sbjct: 48  GLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYF 94


>gi|82659091 staufen isoform c [Homo sapiens]
          Length = 502

 Score = 27.7 bits (60), Expect = 8.4
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 23  ISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGISK 62
           ISQVFEI +  +L   F    L   AR + PP  K  ++K
Sbjct: 105 ISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKNFVTK 144


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,851,752
Number of Sequences: 37866
Number of extensions: 318705
Number of successful extensions: 631
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 610
Number of HSP's gapped (non-prelim): 15
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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