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Search of human proteins with 90403586
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90403586 heparanase 2 [Homo sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90403586 heparanase 2 [Homo sapiens] 1194 0.0
gi|94721347 heparanase [Homo sapiens] 438 e-123
gi|148746204 heparanase [Homo sapiens] 438 e-123
gi|41393608 reticulon 3 isoform b [Homo sapiens] 32 2.1
gi|195963433 syncytin precursor [Homo sapiens] 31 3.7
gi|48949851 syncytin precursor [Homo sapiens] 31 3.7
gi|73747917 transporter 2, ATP-binding cassette, sub-family B is... 30 8.2
gi|73747915 transporter 2, ATP-binding cassette, sub-family B is... 30 8.2
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 30 8.2
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 30 8.2
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 30 8.2
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs... 30 8.2
>gi|90403586 heparanase 2 [Homo sapiens]
Length = 592
Score = 1194 bits (3088), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL 60
MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL
Sbjct: 1 MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL 60
Query: 61 ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT 120
ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT
Sbjct: 61 ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT 120
Query: 121 DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK 180
DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK
Sbjct: 121 DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK 180
Query: 181 AAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS 240
AAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS
Sbjct: 181 AAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS 240
Query: 241 ALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRAS 300
ALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRAS
Sbjct: 241 ALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRAS 300
Query: 301 LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ 360
LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ
Sbjct: 301 LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ 360
Query: 361 IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR 420
IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR
Sbjct: 361 IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR 420
Query: 421 HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI 480
HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI
Sbjct: 421 HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI 480
Query: 481 YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV 540
YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV
Sbjct: 481 YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV 540
Query: 541 QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALACRYR 592
QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALACRYR
Sbjct: 541 QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALACRYR 592
>gi|94721347 heparanase [Homo sapiens]
Length = 543
Score = 438 bits (1126), Expect = e-123
Identities = 244/558 (43%), Positives = 328/558 (58%), Gaps = 29/558 (5%)
Query: 33 LHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDG- 91
L L L G P + R A ++ ++ LD T+ P+ V+ +FLS+ +D ++ D
Sbjct: 13 LMLLLLGPLGPLSPGALPRPAQAQD--VVDLDFFTQEPLHLVSPSFLSVTIDANLATDPR 70
Query: 92 WLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDI 151
+L L S +L TLARGLSPA+LRFGG +TDFL F +P K Y+ DI
Sbjct: 71 FLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIF----DPKKESTFEERSYWQSQVNQDI 126
Query: 152 VRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLY 211
CK P + E R + +LL+E + + N + S+D LY
Sbjct: 127 ------------CKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLY 174
Query: 212 NFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHG 271
FA+CSGL LIF LNAL R + WNSS+A LL Y +SK YNISWELGNEPN++
Sbjct: 175 TFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKAD 234
Query: 272 RAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAV 331
+NGSQLG+D+IQL LL+ + A LYGP++G+PR+ +L F+K G +D+V
Sbjct: 235 IFINGSQLGEDFIQLHKLLRK-STFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSV 293
Query: 332 TWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTN 391
TW H Y++GR DFL +LD ++K+ +VV + PGKK+WL + GG
Sbjct: 294 TWHHYYLNGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAP 353
Query: 392 NLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRL 451
LSD++AAGF+WL+ LG+ A GI+VV+R FF G HLVD+NF+PLPDYWLSLL+K+L
Sbjct: 354 LLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKL 413
Query: 452 IGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKI 511
+G KVL V G +R+ KLR+Y HCTN N Y G +TL+ INLH K +
Sbjct: 414 VGTKVLMASVQGSKRR---------KLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYL 464
Query: 512 KLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVI 571
+L +K V +YLL+P G GL SKSVQLNG L MVDD TLP L +PLR G +L +
Sbjct: 465 RLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGL 524
Query: 572 PPVTMGFFVVKNVNALAC 589
P + FFV++N AC
Sbjct: 525 PAFSYSFFVIRNAKVAAC 542
>gi|148746204 heparanase [Homo sapiens]
Length = 543
Score = 438 bits (1126), Expect = e-123
Identities = 244/558 (43%), Positives = 328/558 (58%), Gaps = 29/558 (5%)
Query: 33 LHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDG- 91
L L L G P + R A ++ ++ LD T+ P+ V+ +FLS+ +D ++ D
Sbjct: 13 LMLLLLGPLGPLSPGALPRPAQAQD--VVDLDFFTQEPLHLVSPSFLSVTIDANLATDPR 70
Query: 92 WLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDI 151
+L L S +L TLARGLSPA+LRFGG +TDFL F +P K Y+ DI
Sbjct: 71 FLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIF----DPKKESTFEERSYWQSQVNQDI 126
Query: 152 VRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLY 211
CK P + E R + +LL+E + + N + S+D LY
Sbjct: 127 ------------CKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLY 174
Query: 212 NFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHG 271
FA+CSGL LIF LNAL R + WNSS+A LL Y +SK YNISWELGNEPN++
Sbjct: 175 TFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKAD 234
Query: 272 RAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAV 331
+NGSQLG+D+IQL LL+ + A LYGP++G+PR+ +L F+K G +D+V
Sbjct: 235 IFINGSQLGEDFIQLHKLLRK-STFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSV 293
Query: 332 TWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTN 391
TW H Y++GR DFL +LD ++K+ +VV + PGKK+WL + GG
Sbjct: 294 TWHHYYLNGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAP 353
Query: 392 NLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRL 451
LSD++AAGF+WL+ LG+ A GI+VV+R FF G HLVD+NF+PLPDYWLSLL+K+L
Sbjct: 354 LLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKL 413
Query: 452 IGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKI 511
+G KVL V G +R+ KLR+Y HCTN N Y G +TL+ INLH K +
Sbjct: 414 VGTKVLMASVQGSKRR---------KLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYL 464
Query: 512 KLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVI 571
+L +K V +YLL+P G GL SKSVQLNG L MVDD TLP L +PLR G +L +
Sbjct: 465 RLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGL 524
Query: 572 PPVTMGFFVVKNVNALAC 589
P + FFV++N AC
Sbjct: 525 PAFSYSFFVIRNAKVAAC 542
>gi|41393608 reticulon 3 isoform b [Homo sapiens]
Length = 1013
Score = 31.6 bits (70), Expect = 2.1
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 145 KNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHL-VLLKEQFSNTYSNLILT 203
K DD V DK+ I++ D + L+ ++A + + LL QFS+T + L
Sbjct: 247 KESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTNAALEEV 306
Query: 204 ARSLDKLYNFAD 215
+R ++ ++NF +
Sbjct: 307 SRCVNDMHNFTN 318
>gi|195963433 syncytin precursor [Homo sapiens]
Length = 538
Score = 30.8 bits (68), Expect = 3.7
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 19/109 (17%)
Query: 272 RAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLD-----GFMKVAGS 326
R +NGS ++ L+ P+ IY+ LY I +PR + +L G + G+
Sbjct: 278 RCLNGSSESMCFLSF--LVPPMTIYTEQDLYSYVISKPRNKRVPILPFVIGAGVLGALGT 335
Query: 327 TVDAVTWQHCY-------IDGRVVKVMDFLKTRLLDTLSDQIRKIQKVV 368
+ +T + ++G + +V D L TL DQ+ + VV
Sbjct: 336 GIGGITTSTQFYYKLSQELNGDMERVADSLV-----TLQDQLNSLAAVV 379
>gi|48949851 syncytin precursor [Homo sapiens]
Length = 538
Score = 30.8 bits (68), Expect = 3.7
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 19/109 (17%)
Query: 272 RAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLD-----GFMKVAGS 326
R +NGS ++ L+ P+ IY+ LY I +PR + +L G + G+
Sbjct: 278 RCLNGSSESMCFLSF--LVPPMTIYTEQDLYSYVISKPRNKRVPILPFVIGAGVLGALGT 335
Query: 327 TVDAVTWQHCY-------IDGRVVKVMDFLKTRLLDTLSDQIRKIQKVV 368
+ +T + ++G + +V D L TL DQ+ + VV
Sbjct: 336 GIGGITTSTQFYYKLSQELNGDMERVADSLV-----TLQDQLNSLAAVV 379
>gi|73747917 transporter 2, ATP-binding cassette, sub-family B
isoform 2 [Homo sapiens]
Length = 653
Score = 29.6 bits (65), Expect = 8.2
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 286 LKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTV-----DAVTWQHCYIDG 340
LK L +R +L GPN G + V ALL + G V ++HCY+
Sbjct: 486 LKGLTFTLRPGEVTALVGPN-GSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHS 544
Query: 341 RVVKV 345
+VV V
Sbjct: 545 QVVSV 549
>gi|73747915 transporter 2, ATP-binding cassette, sub-family B
isoform 1 [Homo sapiens]
Length = 703
Score = 29.6 bits (65), Expect = 8.2
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 286 LKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTV-----DAVTWQHCYIDG 340
LK L +R +L GPN G + V ALL + G V ++HCY+
Sbjct: 486 LKGLTFTLRPGEVTALVGPN-GSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHS 544
Query: 341 RVVKV 345
+VV V
Sbjct: 545 QVVSV 549
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 29.6 bits (65), Expect = 8.2
Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 17/63 (26%)
Query: 235 SWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIR 294
S+N A+++L + S YN W L Q+G+ Y +L +Q R
Sbjct: 484 SYNCKEAINILSHLPSHHYNTGWVL-----------------CQIGRAYFELSEYMQAER 526
Query: 295 IYS 297
I+S
Sbjct: 527 IFS 529
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 29.6 bits (65), Expect = 8.2
Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 17/63 (26%)
Query: 235 SWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIR 294
S+N A+++L + S YN W L Q+G+ Y +L +Q R
Sbjct: 478 SYNCKEAINILSHLPSHHYNTGWVL-----------------CQIGRAYFELSEYMQAER 520
Query: 295 IYS 297
I+S
Sbjct: 521 IFS 523
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 29.6 bits (65), Expect = 8.2
Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 2/34 (5%)
Query: 157 ALDKQKGCKIAQHPDVMLE--LQREKAAQMHLVL 188
+LD Q+G QHP+++L+ L RE+ A HL+L
Sbjct: 179 SLDVQQGADGPQHPEMVLQSPLDREEEAVHHLIL 212
>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 29.6 bits (65), Expect = 8.2
Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 2/34 (5%)
Query: 157 ALDKQKGCKIAQHPDVMLE--LQREKAAQMHLVL 188
+LD Q+G QHP+++L+ L RE+ A HL+L
Sbjct: 179 SLDVQQGADGPQHPEMVLQSPLDREEEAVHHLIL 212
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,879,818
Number of Sequences: 37866
Number of extensions: 1016932
Number of successful extensions: 2222
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2211
Number of HSP's gapped (non-prelim): 12
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.