Search of human proteins with 87240000

Search of human proteins with 87240000

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|87240000 5,10-methylenetetrahydrofolate reductase [Homo
sapiens]
         (656 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|87240000 5,10-methylenetetrahydrofolate reductase [Homo sapiens]  1355   0.0  
gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo sapi...    33   0.64 
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    32   2.4  
gi|33695078 protein phosphatase 2, regulatory subunit B'', beta ...    31   3.2  
gi|41349491 protein phosphatase 2, regulatory subunit B'', beta ...    31   3.2  
gi|109150416 peroxidasin [Homo sapiens]                                31   4.1  
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              31   4.1  
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]       30   7.0  
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]        30   7.0  
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]       30   7.0  
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]        30   7.0  
gi|24432032 zinc finger protein 503 [Homo sapiens]                     30   7.0  
gi|66932994 histidine acid phosphatase domain containing 2A isof...    30   7.0  
gi|222352127 sidekick 2 [Homo sapiens]                                 30   9.2  
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    30   9.2  

>gi|87240000 5,10-methylenetetrahydrofolate reductase [Homo sapiens]
          Length = 656

 Score = 1355 bits (3507), Expect = 0.0
 Identities = 656/656 (100%), Positives = 656/656 (100%)

Query: 1   MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF 60
           MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF
Sbjct: 1   MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF 60

Query: 61  SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC 120
           SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC
Sbjct: 61  SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC 120

Query: 121 GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK 180
           GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK
Sbjct: 121 GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK 180

Query: 181 HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 240
           HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV
Sbjct: 181 HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV 240

Query: 241 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 300
           KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE
Sbjct: 241 KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE 300

Query: 301 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE 360
           LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE
Sbjct: 301 LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE 360

Query: 361 DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM 420
           DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM
Sbjct: 361 DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM 420

Query: 421 WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL 480
           WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL
Sbjct: 421 WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL 480

Query: 481 TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL 540
           TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL
Sbjct: 481 TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL 540

Query: 541 VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE 600
           VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE
Sbjct: 541 VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE 600

Query: 601 EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP 656
           EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP
Sbjct: 601 EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP 656


>gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo
           sapiens]
          Length = 524

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 38  DPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLI 77
           DP    R+ E++RRR  SG KW  + FFP  T      L+
Sbjct: 174 DPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALL 213


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 34/133 (25%), Positives = 55/133 (41%), Gaps = 22/133 (16%)

Query: 66  PPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETI 125
           P R  +  V +  + + MA GG       W P+ D G D E    ++  TA+  C   T 
Sbjct: 481 PARLVKFLVGMKGKDEAMAIGGH------WSPSLD-GPDPEKDPSVLIKTAIRCCKALTG 533

Query: 126 LHMTCCRQ--RLEEITGH----LHKAKQL--GLKNIMALRGD-----PIGDQWEEEEGGF 172
           + ++ C Q  R  EI  H     HK + +   ++ ++    D     P   +WE    G 
Sbjct: 534 IDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRG- 592

Query: 173 NYAVDLVKHIRSE 185
            Y   LV+ ++ E
Sbjct: 593 -YKQQLVEKLQGE 604


>gi|33695078 protein phosphatase 2, regulatory subunit B'', beta
           isoform 1 [Homo sapiens]
          Length = 575

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 17/44 (38%), Positives = 25/44 (56%)

Query: 190 FDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEA 233
           +DI VA    G P    FEA+L  +++K+SA    +  + FFEA
Sbjct: 510 YDILVAEETAGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEA 553


>gi|41349491 protein phosphatase 2, regulatory subunit B'', beta
           isoform 2 [Homo sapiens]
          Length = 176

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 17/44 (38%), Positives = 25/44 (56%)

Query: 190 FDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEA 233
           +DI VA    G P    FEA+L  +++K+SA    +  + FFEA
Sbjct: 111 YDILVAEETAGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEA 154


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 259  IQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGL 318
            I  YH  R    LS     +++K+ I+  +  +   R YG  L + L   L+   LVPG 
Sbjct: 1167 IPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGS 1226

Query: 319  HFYTLNREMATTEVLKRL----GMWTEDP 343
                    + +T+  KRL     +W E+P
Sbjct: 1227 RLGPTLMCLLSTQ-FKRLRDGDRLWYENP 1254


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)

Query: 17   GSASSG--SESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLE 63
            G   SG  SES   SSR ++P +  ER  R R K + R  S D+  S E
Sbjct: 1014 GRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRE 1062


>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
          Length = 1863

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 24/149 (16%)

Query: 438  YLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPN-INGKP---- 492
            ++  E + NG K+T L    E     T L++ +L     Q  LT+  +P+   G P    
Sbjct: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342

Query: 493  --SSDPIVGWGPS---GGYVFQ-----------KAYLEFFTSRETAEALLQVLKKYELRV 536
              SS   + W  S   GG   Q           K + E  T R T+  +  +L  +E + 
Sbjct: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKF 1402

Query: 537  NYHLVNVKGENITNAPELQPNAVTWGIFP 565
                +NV G   T+ P  +    T G  P
Sbjct: 1403 RVRAINVYG---TSEPSQESELTTVGEKP 1428


>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
          Length = 1914

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 24/149 (16%)

Query: 438  YLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPN-INGKP---- 492
            ++  E + NG K+T L    E     T L++ +L     Q  LT+  +P+   G P    
Sbjct: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342

Query: 493  --SSDPIVGWGPS---GGYVFQ-----------KAYLEFFTSRETAEALLQVLKKYELRV 536
              SS   + W  S   GG   Q           K + E  T R T+  +  +L  +E + 
Sbjct: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKF 1402

Query: 537  NYHLVNVKGENITNAPELQPNAVTWGIFP 565
                +NV G   T+ P  +    T G  P
Sbjct: 1403 RVRAINVYG---TSEPSQESELTTVGEKP 1428


>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
          Length = 1794

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 24/149 (16%)

Query: 438  YLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPN-INGKP---- 492
            ++  E + NG K+T L    E     T L++ +L     Q  LT+  +P+   G P    
Sbjct: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273

Query: 493  --SSDPIVGWGPS---GGYVFQ-----------KAYLEFFTSRETAEALLQVLKKYELRV 536
              SS   + W  S   GG   Q           K + E  T R T+  +  +L  +E + 
Sbjct: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKF 1333

Query: 537  NYHLVNVKGENITNAPELQPNAVTWGIFP 565
                +NV G   T+ P  +    T G  P
Sbjct: 1334 RVRAINVYG---TSEPSQESELTTVGEKP 1359


>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
          Length = 1845

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 24/149 (16%)

Query: 438  YLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPN-INGKP---- 492
            ++  E + NG K+T L    E     T L++ +L     Q  LT+  +P+   G P    
Sbjct: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273

Query: 493  --SSDPIVGWGPS---GGYVFQ-----------KAYLEFFTSRETAEALLQVLKKYELRV 536
              SS   + W  S   GG   Q           K + E  T R T+  +  +L  +E + 
Sbjct: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKF 1333

Query: 537  NYHLVNVKGENITNAPELQPNAVTWGIFP 565
                +NV G   T+ P  +    T G  P
Sbjct: 1334 RVRAINVYG---TSEPSQESELTTVGEKP 1359


>gi|24432032 zinc finger protein 503 [Homo sapiens]
          Length = 646

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 9/86 (10%)

Query: 17  GSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNL 76
           GS SS + +       S+ G  PE  +  ++        G    S E  P   A G    
Sbjct: 227 GSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG---- 282

Query: 77  ISRFDRMAAGGPLYIDVTWHPAGDPG 102
                R++ GG + +DV  HP G PG
Sbjct: 283 -----RISCGGGINVDVNQHPDGGPG 303


>gi|66932994 histidine acid phosphatase domain containing 2A isoform 4
            [Homo sapiens]
          Length = 1194

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 14/51 (27%), Positives = 28/51 (54%)

Query: 239  FVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKD 289
            F K  T+    C +VP I+P++  H+   L ++  +E  Q  ++V +P ++
Sbjct: 971  FAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVPPMETSQPYEEVSQPCQE 1021


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 26/150 (17%)

Query: 299  IELAVSLCQELLASGLVPG---LHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHP 355
            +E+     ++  A+GL P    L   T        E  + L + TE   RP P    + P
Sbjct: 1350 VEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP---PSRP 1406

Query: 356  KRREEDVRP--IFWASRPKS-----YIYRTQEWDEFPNGRWG--------NSSSPAFGEL 400
              ++EDVR   +  +  P S       Y T +  E P+GRW         N+SS     L
Sbjct: 1407 MVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRL 1466

Query: 401  KDYYLFYLKSKSPKEELLKMWGEELTSEES 430
            K +  +  + K+  +      G+   SEES
Sbjct: 1467 KPFTSYKFRVKATND-----IGDSEFSEES 1491


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 326 EMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFP 385
           E+   ++L+   M   D RRP P      P  ++E  +P F A  PK++        E P
Sbjct: 480 EVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVP 539


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,625,436
Number of Sequences: 37866
Number of extensions: 1342895
Number of successful extensions: 3156
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3140
Number of HSP's gapped (non-prelim): 23
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.