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Search of human proteins with 8394402
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8394402 taste receptor T2R4 [Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8394402 taste receptor T2R4 [Homo sapiens] 585 e-167
gi|12965176 taste receptor, type 2, member 7 [Homo sapiens] 143 2e-34
gi|116875819 taste receptor, type 2, member 39 [Homo sapiens] 138 5e-33
gi|8394398 taste receptor T2R3 [Homo sapiens] 134 1e-31
gi|28882033 taste receptor, type 2, member 40 [Homo sapiens] 130 1e-30
gi|116268093 taste receptor, type 2, member 41 [Homo sapiens] 127 2e-29
gi|12965174 taste receptor, type 2, member 8 [Homo sapiens] 119 3e-27
gi|12965180 taste receptor, type 2, member 10 [Homo sapiens] 114 1e-25
gi|154937355 taste receptor, type 2, member 20 [Homo sapiens] 114 1e-25
gi|12965172 taste receptor, type 2, member 9 [Homo sapiens] 113 2e-25
gi|9625043 taste receptor T2R1 [Homo sapiens] 108 6e-24
gi|223278415 taste receptor, type 2, member 38 [Homo sapiens] 108 7e-24
gi|12965178 taste receptor, type 2, member 13 [Homo sapiens] 106 2e-23
gi|116235464 taste receptor, type 2, member 43 [Homo sapiens] 105 4e-23
gi|116235454 taste receptor, type 2, member 31 [Homo sapiens] 104 8e-23
gi|29126245 taste receptor, type 2, member 45 [Homo sapiens] 101 7e-22
gi|9507173 taste receptor T2R5 [Homo sapiens] 101 7e-22
gi|117414133 taste receptor, type 2, member 46 [Homo sapiens] 100 1e-21
gi|154937357 taste receptor, type 2, member 50 [Homo sapiens] 100 2e-21
gi|31088852 taste receptor, type 2, member 42 [Homo sapiens] 99 3e-21
gi|12965182 taste receptor, type 2, member 14 [Homo sapiens] 99 3e-21
gi|28973795 taste receptor, type 2, member 60 [Homo sapiens] 99 6e-21
gi|148235367 type 2 taste receptor member 30 [Homo sapiens] 94 1e-19
gi|28882035 taste receptor, type 2, member 19 [Homo sapiens] 92 4e-19
gi|8394395 taste receptor T2R16 [Homo sapiens] 80 3e-15
gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo sap... 32 0.52
gi|47271479 Na+/H+ exchanger domain containing 2 [Homo sapiens] 32 0.52
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 32 0.68
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 31 1.5
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 31 1.5
>gi|8394402 taste receptor T2R4 [Homo sapiens]
Length = 299
Score = 585 bits (1507), Expect = e-167
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG 60
MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG
Sbjct: 1 MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG 60
Query: 61 LFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL 120
LFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL
Sbjct: 61 LFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL 120
Query: 121 LKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVS 180
LKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVS
Sbjct: 121 LKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVS 180
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI
Sbjct: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299
PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK
Sbjct: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299
>gi|12965176 taste receptor, type 2, member 7 [Homo sapiens]
Length = 318
Score = 143 bits (361), Expect = 2e-34
Identities = 101/290 (34%), Positives = 158/290 (54%), Gaps = 21/290 (7%)
Query: 19 VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSN----T 74
VGI+ N FI +VNC WVK +I+S D IL SL I+R +L + L++ V T
Sbjct: 19 VGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLCVILLDCFILVLYPDVYAT 78
Query: 75 ERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLL 134
+ + + FF + + S+WF T L+I Y KI NF H +FL +K I I +LL
Sbjct: 79 GKEMRIIDFF---WTLTNHLSIWFATCLSIYYFFKIGNFFHPLFLWMKWRIDRVISWILL 135
Query: 135 ACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGI-----LSLVVSLVLSSSLQF 189
CV++S F + L T + + F V + T+ S + S + L L++ L F
Sbjct: 136 GCVVLSVFIS-LPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHASTKLFLNLATLLPF 194
Query: 190 IINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQ 249
+ + S LLI SLRRHI++MQ +ATG +P TEAHV A+K ++ FL+L+I Y ++ L+
Sbjct: 195 CVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISFLLLFIAYYLSFLIA 254
Query: 250 YLPFYAGMDMGTKSICLIF----ATLYSPGHSVLIIITHPKLKTTAKKIL 295
++ M + +IF A +Y HS ++I+ + KL+ + K++
Sbjct: 255 TSSYF----MPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVI 300
>gi|116875819 taste receptor, type 2, member 39 [Homo sapiens]
Length = 338
Score = 138 bits (348), Expect = 5e-33
Identities = 97/297 (32%), Positives = 156/297 (52%), Gaps = 10/297 (3%)
Query: 5 FYFSAIIASVILNF-VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFL 63
F + I+A ++ + +GII N FI ++ WV++ +S+S RIL L ++R + L +
Sbjct: 32 FLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMM 91
Query: 64 VN-TIYFVSSN--TERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL 120
+ TI S + +E +VY + F + F+FL+ S+WF L+ Y VKI NF + +FL
Sbjct: 92 LEITISSTSLSFYSEDAVYYA--FKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLK 149
Query: 121 LKRNISPKIPRLLLACVLISAFTTCLYITLSQA---SPFPELVTTRNNTSFNISEGILSL 177
L+ I+ IP LL V IS + I + + FP + ++ ++ L
Sbjct: 150 LRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTYLSEINVVGL 209
Query: 178 VVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLI 237
L I+ + +A+LLI SL+RH M NATG +P EAH+GA+K + YFLI
Sbjct: 210 AFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKAISYFLI 269
Query: 238 LYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKI 294
LYI +VA + YL ++ ++C I Y HS+L+I +P L+ K++
Sbjct: 270 LYIFNAVALFI-YLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAWKRL 325
>gi|8394398 taste receptor T2R3 [Homo sapiens]
Length = 316
Score = 134 bits (337), Expect = 1e-31
Identities = 91/277 (32%), Positives = 144/277 (51%), Gaps = 6/277 (2%)
Query: 19 VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYF-VSSNTERS 77
+GI++N FI +VN +W K+ R+S SD I+ +L + R ++L + L ++ S NT S
Sbjct: 19 LGILVNCFIELVNGSSWFKTKRMSLSDFIITTLALLRIILLCIILTDSFLIEFSPNTHDS 78
Query: 78 VYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACV 137
+ + + F + S+W T L +LYC+KI +F H FL LK +S + +LL +
Sbjct: 79 GIIMQIIDVSWTFTNHLSIWLATCLGVLYCLKIASFSHPTFLWLKWRVSRVMVWMLLGAL 138
Query: 138 LISAFTTCLYIT-LSQASPFPELVTTRNNTSF---NISEGILSLVVSLVLSSSLQFIINV 193
L+S +T I S F + TRN T SE L V+ L I+++
Sbjct: 139 LLSCGSTASLINEFKLYSVFRGIEATRNVTEHFRKKRSEYYLIHVLG-TLWYLPPLIVSL 197
Query: 194 TSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQYLPF 253
S SLLI SL RH ++M +N T +P TEAH A+++++ F L++ Y +A L+
Sbjct: 198 ASYSLLIFSLGRHTRQMLQNGTSSRDPTTEAHKRAIRIILSFFFLFLLYFLAFLIASFGN 257
Query: 254 YAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTT 290
+ K I + Y GHS ++I+ + KLK T
Sbjct: 258 FLPKTKMAKMIGEVMTMFYPAGHSFILILGNSKLKQT 294
>gi|28882033 taste receptor, type 2, member 40 [Homo sapiens]
Length = 323
Score = 130 bits (328), Expect = 1e-30
Identities = 89/293 (30%), Positives = 149/293 (50%), Gaps = 14/293 (4%)
Query: 10 IIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIY- 68
++ S I GI+ + FIT + W + + + DRI+ L +R L+ ++ I+
Sbjct: 22 LVVSGIECITGILGSGFITAIYGAEWARGKTLPTGDRIMLMLSFSRLLLQIWMMLENIFS 81
Query: 69 --FVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNIS 126
F + SVY+ F + +FL+ S++WF L + YC++I NF H +F L+KR I
Sbjct: 82 LLFRIVYNQNSVYI--LFKVITVFLNHSNLWFAAWLKVFYCLRIANFNHPLFFLMKRKII 139
Query: 127 PKIPRLLLACVLIS-AFTTCLY-----ITLSQASPFPELVTTRNNTSFNISEGILSLVVS 180
+P LL VL+S +F+ L + ++ + P P +T + +++LV
Sbjct: 140 VLMPWLLRLSVLVSLSFSFPLSRDVFNVYVNSSIPIPSSNSTEKK--YFSETNMVNLVFF 197
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
+ + I+ + +A+LLI SL+RH M NATG +P +AH+GA+K YFLILYI
Sbjct: 198 YNMGIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMKAHIGAIKATSYFLILYI 257
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKK 293
++A + + +C I Y GHSV +I+ +P L+ K+
Sbjct: 258 FNAIALFLSTSNIFDTYS-SWNILCKIIMAAYPAGHSVQLILGNPGLRRAWKR 309
>gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]
Length = 307
Score = 127 bits (318), Expect = 2e-29
Identities = 95/289 (32%), Positives = 148/289 (51%), Gaps = 13/289 (4%)
Query: 15 ILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNT 74
+L+ +GI N FI +V + W++ R+ D IL SLG +RF + + V+ Y+ +
Sbjct: 15 LLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKV 74
Query: 75 ERSVYLSA-FFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLL 133
E S L FF L + FL+S++ WF + L++L+CVKI N HS FL LK +P LL
Sbjct: 75 EYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLL 134
Query: 134 LACVLISAFTTCLYITLSQ-------ASPFPELVTTRNNTSFNISEGILSLVVSLVLSSS 186
L VLIS T L+ ++ F +T + NT E + LV+ S
Sbjct: 135 LGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRI---ETYYFPSLKLVI-WS 190
Query: 187 LQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVAT 246
+ F + + S LLI+SLRRH Q+MQ N +P T+AH A+K ++ FLILY ++
Sbjct: 191 IPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSL 250
Query: 247 LVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
++ F + M I L H ++I ++ KL++ ++L
Sbjct: 251 IIDAAKFIS-MQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLL 298
>gi|12965174 taste receptor, type 2, member 8 [Homo sapiens]
Length = 309
Score = 119 bits (298), Expect = 3e-27
Identities = 84/286 (29%), Positives = 147/286 (51%), Gaps = 5/286 (1%)
Query: 19 VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNTERSV 78
+GI+ N +I +VN W+K +IS+ D IL +L I R ++ + +VN I V + +
Sbjct: 19 LGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTK 78
Query: 79 YLSAFFVLCFM-FLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACV 137
+ F F + ++W T LN+ Y +KI + H +FL LK I + +LL C
Sbjct: 79 NKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCF 138
Query: 138 LISAFTTCLY-ITLSQASPFPELVTTRNNTS--FNISEGILSLVVSLV-LSSSLQFIINV 193
IS + + I LS F + + N + F++S+ ++L L + + FI+++
Sbjct: 139 AISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSL 198
Query: 194 TSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQYLPF 253
S LL+ SL RH ++++ ATG +P TE HV A+K M F+ + Y +++++ +
Sbjct: 199 ISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYYISSILMTFSY 258
Query: 254 YAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299
I A LY GHS+++I+ + KL+ T ++L +K
Sbjct: 259 LMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVRMLTCRK 304
>gi|12965180 taste receptor, type 2, member 10 [Homo sapiens]
Length = 307
Score = 114 bits (285), Expect = 1e-25
Identities = 88/300 (29%), Positives = 152/300 (50%), Gaps = 13/300 (4%)
Query: 1 MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG 60
MLR+ I V + G++ N FI +VNC K+ ++S+ IL L I+R ++
Sbjct: 1 MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKN-KLSTIGFILTGLAISRIFLIW 59
Query: 61 LFLVNT-IYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFL 119
+ + + I S N S L + ++ + SS+WF T L+I Y +KI NF + +FL
Sbjct: 60 IIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFL 119
Query: 120 LLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNI----SEGIL 175
LK + +P ++ +LIS+ YI + T+N+T +++ SE +
Sbjct: 120 WLKSRTNMVLP-FMIVFLLISSLLNFAYI-----AKILNDYKTKNDTVWDLNMYKSEYFI 173
Query: 176 SLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYF 235
++ L L F +++ + LI SL RH ++MQ N TG + TEAHV AMK+++ F
Sbjct: 174 KQIL-LNLGVIFFFTLSLITCIFLIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLISF 232
Query: 236 LILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
+IL+I Y + ++ F + + +Y GHS ++I+ + KLK + ++L
Sbjct: 233 IILFILYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVL 292
>gi|154937355 taste receptor, type 2, member 20 [Homo sapiens]
Length = 309
Score = 114 bits (284), Expect = 1e-25
Identities = 80/295 (27%), Positives = 144/295 (48%), Gaps = 11/295 (3%)
Query: 4 LFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFL 63
+F ++A ++ NF N FI ++N WVK +ISS+D+I+ +L ++R +L + L
Sbjct: 8 VFSILVVVAFILGNFA----NGFIALINFIAWVKRQKISSADQIIAALAVSRVGLLWVIL 63
Query: 64 VNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKR 123
++ V + T ++ + F + + S+W T L+I Y +KI NF +F LKR
Sbjct: 64 LHWYSTVLNPTSSNLKVIIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHHLKR 123
Query: 124 NISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNI---SEGILSLVVS 180
K ++L VL S F ++ + N ++ I + LS +
Sbjct: 124 ----KAKSVVLVIVLGSLFFLVCHLVMKHTYINVWTEECEGNVTWKIKLRNAMHLSNLTV 179
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
+L++ + F + + S LLI+SL +H++KMQ + G +P T+ H+ A++ + FLIL
Sbjct: 180 AMLANLIPFTLTLISFLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLA 239
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
Y + ++ + F +C F +Y HS ++I + LK T +L
Sbjct: 240 IYFLCLIISFWNFKMRPKEIVLMLCQAFGIIYPSFHSFILIWGNKTLKQTFLSVL 294
>gi|12965172 taste receptor, type 2, member 9 [Homo sapiens]
Length = 312
Score = 113 bits (283), Expect = 2e-25
Identities = 90/289 (31%), Positives = 146/289 (50%), Gaps = 14/289 (4%)
Query: 19 VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVS-SNTERS 77
+GI N FI +VNC W+K IS D IL SL I+R +L + ++ + + T +
Sbjct: 19 IGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGN 78
Query: 78 VYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACV 137
L + + + F ++SS+WF + L+I Y +KI N H F LK I+ + +LL
Sbjct: 79 SVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSF 138
Query: 138 LISAFTTC-----LYITLSQASPFPELVTTRNNTSFNISE--GILSLVVSLVLSSSLQFI 190
LIS + ++ L + S E +T + F +S+ G + +L L + FI
Sbjct: 139 LISLIISVPKNDDMWYHLFKVS-HEENITWK----FKVSKIPGTFKQL-TLNLGVMVPFI 192
Query: 191 INVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLVQY 250
+ + S LL+ SL RH ++++ +ATGF +P TEAH+ A+K ++ FL+L I Y LV
Sbjct: 193 LCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMT 252
Query: 251 LPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299
I I ++ HS ++I+ + KL+ K+L F K
Sbjct: 253 SSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVK 301
>gi|9625043 taste receptor T2R1 [Homo sapiens]
Length = 299
Score = 108 bits (270), Expect = 6e-24
Identities = 83/309 (26%), Positives = 143/309 (46%), Gaps = 32/309 (10%)
Query: 4 LFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITR-FLMLGLF 62
+ YF + +VI +GI N I VVN +K +++ D +L L ++R FL L +F
Sbjct: 7 IIYF---LLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIF 63
Query: 63 LVNTIYFVSSNTERSVYLSAFFVLC------FMFLDSSSVWFVTLLNILYCVKITNFQHS 116
VN I V F++C +F++ +W T L + YC K+ + +H
Sbjct: 64 YVNVI----------VIFFIEFIMCSANCAILLFINELELWLATWLGVFYCAKVASVRHP 113
Query: 117 VFLLLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTT--RNNTSFNISEGI 174
+F+ LK IS +P ++L +L + C++ + P + N + + +
Sbjct: 114 LFIWLKMRISKLVPWMILGSLLYVSM-ICVFHSKYAGFMVPYFLRKFFSQNATIQKEDTL 172
Query: 175 LSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVY 234
+ S V S+ +I + + LLI SL RH ++M+ G P A + A+ ++
Sbjct: 173 AIQIFSFVAEFSVPLLIFLFAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILS 232
Query: 235 FLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATL----YSPGHSVLIIITHPKLKTT 290
FLILY + + + F + + + +F L Y GHS+++I+ +PKLK
Sbjct: 233 FLILYFSHCMIKV-----FLSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQN 287
Query: 291 AKKILCFKK 299
AKK L K
Sbjct: 288 AKKFLLHSK 296
>gi|223278415 taste receptor, type 2, member 38 [Homo sapiens]
Length = 333
Score = 108 bits (269), Expect = 7e-24
Identities = 78/294 (26%), Positives = 135/294 (45%), Gaps = 8/294 (2%)
Query: 10 IIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYF 69
+ SV+ VG + N F+ +VN VK +S+SD +L L I+R + GL ++ I
Sbjct: 19 LFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHGLLFLSAIQL 78
Query: 70 VSSN--TERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISP 127
+E + ++ +M + +++W L++LYC K+ F H+ + L +S
Sbjct: 79 THFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSR 138
Query: 128 KIPRLLLACVLISAFTTCLYITLSQASPFPELVTT---RNNTSFNISEGILSLVVSLV-- 182
KI ++LL +L S T L + + P + T NNT N L+L S +
Sbjct: 139 KISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFC 198
Query: 183 -LSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIP 241
L S F++ + S+ +L SL RH++ M+ +P EAH+ A+K +V F ++
Sbjct: 199 YLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLEAHIKALKSLVSFFCFFVI 258
Query: 242 YSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
S A + D +C+ GH+ ++I + KL+ IL
Sbjct: 259 SSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISGNAKLRRAVMTIL 312
>gi|12965178 taste receptor, type 2, member 13 [Homo sapiens]
Length = 303
Score = 106 bits (265), Expect = 2e-23
Identities = 81/294 (27%), Positives = 147/294 (50%), Gaps = 32/294 (10%)
Query: 10 IIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYF 69
IIA I +G + N FI ++NC WV +SS D++L L I+R ++ LV+ +F
Sbjct: 13 IIAEFI---IGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVS--WF 67
Query: 70 VSSNTERSVYLSAFF------VLCFMFLDSS--SVWFVTLLNILYCVKITNFQHSVFLLL 121
++ + YL+ F ++ F ++ S+ ++W T+ +I Y +KI +F FL L
Sbjct: 68 LALH-----YLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYL 122
Query: 122 KRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPE--LVTTRNNTSFNISEG-----I 174
K ++ I +LL ++ L++ L Q + + L NT++N S
Sbjct: 123 KWRVNKVILMILLGTLVF------LFLNLIQINMHIKDWLDRYERNTTWNFSMSDFETFS 176
Query: 175 LSLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVY 234
+S+ ++ + S F + S LLI SL++H+QKMQ N G +P+T+ H A+K+++
Sbjct: 177 VSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVIS 236
Query: 235 FLILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLK 288
FL+ Y + + L+ ++ + +C HS L+I+ + KL+
Sbjct: 237 FLLFYASFFLCVLISWIS-ELYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLR 289
>gi|116235464 taste receptor, type 2, member 43 [Homo sapiens]
Length = 309
Score = 105 bits (263), Expect = 4e-23
Identities = 81/290 (27%), Positives = 143/290 (49%), Gaps = 15/290 (5%)
Query: 7 FSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNT 66
FS+++ V+ +G N FI +VN W K +IS +D+IL +L ++R +L + L+N
Sbjct: 9 FSSLV--VVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNW 66
Query: 67 IYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNIS 126
V + SV + + ++ S W T L+I Y +KI NF + +FL LKR +
Sbjct: 67 YSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATTLSIFYLLKIANFSNFIFLHLKRRVK 126
Query: 127 PKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTR---NNTSFNI---SEGILSLVVS 180
I +LL +L F C ++ E+V T+ N ++ I S S +
Sbjct: 127 SVILVMLLGPLL---FLACHLFVIN----MNEIVRTKEFEGNMTWKIKLKSAMYFSNMTV 179
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
++++ + F + + S LLI SL +H++KMQ + G +P T+ H+ A++ ++ FL+L
Sbjct: 180 TMVANLVPFTLTLLSFMLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVISFLLLCA 239
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTT 290
Y ++ ++ F + + C Y H ++I + KLK T
Sbjct: 240 IYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQT 289
>gi|116235454 taste receptor, type 2, member 31 [Homo sapiens]
Length = 309
Score = 104 bits (260), Expect = 8e-23
Identities = 84/295 (28%), Positives = 142/295 (48%), Gaps = 15/295 (5%)
Query: 7 FSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNT 66
FS+++ V+L +G N FI +VN VK +IS +D+IL +L ++R +L + L+N
Sbjct: 9 FSSVV--VVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNW 66
Query: 67 IYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNIS 126
V + SV + + S W T L+I Y +KI NF + +FL LKR +
Sbjct: 67 YSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVK 126
Query: 127 PKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRN---NTSFNI---SEGILSLVVS 180
I +LL +L F C ++ E+V T+ N ++ I S LS
Sbjct: 127 SVILVMLLGPLL---FLACQLFVINMK----EIVRTKEYEGNLTWKIKLRSAVYLSDATV 179
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
L + + F + + LLI SL +H++KMQ + G +P T+ H+ A++ +++FL+L
Sbjct: 180 TTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCA 239
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
Y ++ ++ F + + C Y H ++I + KLK T +L
Sbjct: 240 VYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVL 294
>gi|29126245 taste receptor, type 2, member 45 [Homo sapiens]
Length = 299
Score = 101 bits (252), Expect = 7e-22
Identities = 81/298 (27%), Positives = 135/298 (45%), Gaps = 17/298 (5%)
Query: 4 LFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFL 63
+F ++ VI NF N FI +VN WVK +IS +D+I+ +L ++R +L + L
Sbjct: 8 IFSILVVVTFVIGNFA----NGFIALVNSTEWVKRQKISFADQIVTALAVSRVGLLWVLL 63
Query: 64 VNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKR 123
+N V + SV L + S W T L+I Y +KI NF + +FL LKR
Sbjct: 64 LNWYSTVLNPAFCSVELRTTAYNIWAVTGHFSNWPATSLSIFYLLKIANFSNLIFLRLKR 123
Query: 124 NISPKI------PRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSL 177
+ I P L LAC L + T + R + +S+ +++
Sbjct: 124 RVKSVILVVLLGPLLFLACHLFVVNMNQIVWTKEYEGNMTWKIKLRR--AMYLSDTTVTM 181
Query: 178 VVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLI 237
+ +LV F + + S LL+ SL +H++KMQ + G +P T+ H+ ++ ++ F +
Sbjct: 182 LANLV-----PFTVTLISFLLLVCSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFFL 236
Query: 238 LYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
L Y V+ ++ F + C S H ++I + KLK T +L
Sbjct: 237 LRAIYFVSVIISVWSFKNLENKPVFMFCQAIGFSCSSAHPFILIWGNKKLKQTYLSVL 294
>gi|9507173 taste receptor T2R5 [Homo sapiens]
Length = 299
Score = 101 bits (252), Expect = 7e-22
Identities = 77/287 (26%), Positives = 140/287 (48%), Gaps = 10/287 (3%)
Query: 10 IIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYF 69
++ +V+ +G+I N + V + + W++ SS + I+ L RFL+ L +++ F
Sbjct: 10 MLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQWLIILDLSLF 69
Query: 70 VSSNTERSV-YLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPK 128
+ R + YLS F+VL + +S+WF T L++ YC KIT F +L LK+ +
Sbjct: 70 PLFQSSRWLRYLSIFWVL----VSQASLWFATFLSVFYCKKITTFDRPAYLWLKQ----R 121
Query: 129 IPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLVLSSSLQ 188
L L C L+ F L +T+ F ++ + L S L
Sbjct: 122 AYNLSLWC-LLGYFIINLLLTVQIGLTFYHPPQGNSSIRYPFESWQYLYAFQLNSGSYLP 180
Query: 189 FIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVATLV 248
++ + S+ +LI SL H +KM+ ++ G + + +AH+ A+K + FL+L++ Y +A+
Sbjct: 181 LVVFLVSSGMLIVSLYTHHKKMKVHSAGRRDVRAKAHITALKSLGCFLLLHLVYIMASPF 240
Query: 249 QYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
D+ + I Y HS+++I+ P++K T +KIL
Sbjct: 241 SITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKIL 287
>gi|117414133 taste receptor, type 2, member 46 [Homo sapiens]
Length = 309
Score = 100 bits (250), Expect = 1e-21
Identities = 79/295 (26%), Positives = 142/295 (48%), Gaps = 15/295 (5%)
Query: 7 FSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNT 66
FS +I V+ +G N FI +VN W K +IS +D+IL +L ++R +L + ++N
Sbjct: 9 FSILI--VVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLVLNW 66
Query: 67 IYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNIS 126
+ S+ + + ++ S W T L+I Y +KI NF + +FL LKR +
Sbjct: 67 YATELNPAFNSIEVRITAYNVWAVINHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVK 126
Query: 127 PKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRN---NTSFNI---SEGILSLVVS 180
+ +LL +L F C ++ +++ T+ N ++ I S LS
Sbjct: 127 SVVLVILLGPLL---FLVCHLFVINMN----QIIWTKEYEGNMTWKIKLRSAMYLSNTTV 179
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
+L++ + F + + S LLI SL +H++KMQ + G +P + H+ A++ + FL+L
Sbjct: 180 TILANLVPFTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSMKVHIKALQTVTSFLLLCA 239
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
Y ++ ++ F + + C A Y H ++I + KLK T +L
Sbjct: 240 IYFLSIIMSVWSFESLENKPVFMFCEAIAFSYPSTHPFILIWGNKKLKQTFLSVL 294
>gi|154937357 taste receptor, type 2, member 50 [Homo sapiens]
Length = 299
Score = 100 bits (248), Expect = 2e-21
Identities = 82/298 (27%), Positives = 138/298 (46%), Gaps = 5/298 (1%)
Query: 1 MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLG 60
M+ Y I ++L +G N FI +VN WVK +ISS+D+IL +L ++R +L
Sbjct: 1 MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKKISSADQILTALAVSRIGLLW 60
Query: 61 LFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLL 120
L+N V + SV L ++ + S+W L+I Y +KI NF + +FL
Sbjct: 61 ALLLNWYLTVLNPAFYSVELRITSYNAWVVTNHFSMWLAANLSIFYLLKIANFSNLLFLH 120
Query: 121 LKRNISPKIPRLLLACVLISAFTTC-LYITLSQASPFPELVTTRNNTSFNISEGI-LSLV 178
LKR + I +LL ++ F C L + S + E + + LS +
Sbjct: 121 LKRRVRSVILVILLGTLI---FLVCHLLVANMDESMWAEEYEGNMTGKMKLRNTVHLSYL 177
Query: 179 VSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLIL 238
L S + F +++ S +LI SL +H++KMQ + G + T+ H+ A++ ++ FL+L
Sbjct: 178 TVTTLWSFIPFTLSLISFLMLICSLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLL 237
Query: 239 YIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILC 296
+ + +V + + +Y S ++I KLK T ILC
Sbjct: 238 CAIFFLFLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILIWRTKKLKHTFLLILC 295
>gi|31088852 taste receptor, type 2, member 42 [Homo sapiens]
Length = 314
Score = 99.4 bits (246), Expect = 3e-21
Identities = 76/289 (26%), Positives = 146/289 (50%), Gaps = 7/289 (2%)
Query: 11 IASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNT-IYF 69
IA I++ +G N+FI +VNC +K+ ++ S+D IL L I+ L + L ++ +
Sbjct: 14 IAEFIISMLG---NVFIGLVNCSEGIKNQKVFSADFILTCLAISTIGQLLVILFDSFLVG 70
Query: 70 VSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKI 129
++S+ + L ++ + + + W T L+I Y KI +F HS+FL L+ ++ I
Sbjct: 71 LASHLYTTYRLGKTVIMLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNGMI 130
Query: 130 PRLLLACVLISAFTTC---LYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLVLSSS 186
LL+ + + F + ++I +S +T + S + + + L L L+S
Sbjct: 131 VMLLILSLFLLIFDSLVLEIFIDISLNIIDKSNLTLYLDESKTLYDKLSILKTLLSLTSF 190
Query: 187 LQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPYSVAT 246
+ F + +TS L SL RH + ++ ++ G + TEAH AMK+++ FL L+I + +
Sbjct: 191 IPFSLFLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSL 250
Query: 247 LVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
V F+ + ++ + HS ++I+ + KL+ TA ++L
Sbjct: 251 QVANGIFFMLWNNKYIKFVMLALNAFPSCHSFILILGNSKLRQTAVRLL 299
>gi|12965182 taste receptor, type 2, member 14 [Homo sapiens]
Length = 317
Score = 99.4 bits (246), Expect = 3e-21
Identities = 81/303 (26%), Positives = 145/303 (47%), Gaps = 26/303 (8%)
Query: 4 LFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITR----FLML 59
+F F I+ +I G + N FI +VNC WVK +ISS DRIL +L I+R +L+
Sbjct: 8 IFTFVLIVEFII----GNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIF 63
Query: 60 GLFLVNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFL 119
G + V+ + TE+ + + ++ SVW T L Y +KI NF +S+FL
Sbjct: 64 GSWCVSVFFPALFATEK---MFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFL 120
Query: 120 LLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVV 179
LK ++ +++L +L+++ L I L + R N + + +
Sbjct: 121 YLKW----RVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFS 176
Query: 180 SLVLSSSLQFI-----INVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVY 234
SL++ +S FI +++ LLI S+ +H +KMQ + T+AH G ++ +
Sbjct: 177 SLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITF 236
Query: 235 FLILYIPYSVATLVQYLPFYAGMDMGTKSICL--IFATLYSPGHSVLIIITHPKLKTTAK 292
FL+ Y++ +L ++ + + I L + Y HS ++I+ + KL+ +
Sbjct: 237 FLL----YAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASL 292
Query: 293 KIL 295
+L
Sbjct: 293 SVL 295
>gi|28973795 taste receptor, type 2, member 60 [Homo sapiens]
Length = 318
Score = 98.6 bits (244), Expect = 6e-21
Identities = 80/293 (27%), Positives = 141/293 (48%), Gaps = 23/293 (7%)
Query: 14 VILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSN 73
++L V I N FIT WV + D++L SLG +RF + + + TIY V +
Sbjct: 25 LLLRLVAIAGNGFITAALGVEWVLRRMLLPCDKLLVSLGASRFCLQSVVMGKTIY-VFLH 83
Query: 74 TERSVYLSAFFVLCFM--FLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPR 131
Y L F FL+++++W T L++ YCVKI F H VF LK +S +P
Sbjct: 84 PMAFPYNPVLQFLAFQWDFLNAATLWSSTWLSVFYCVKIATFTHPVFFWLKHKLSGWLPW 143
Query: 132 LLLACVLISAFTTCL--------YITLSQASPFPELVTTRNNTSFNISEGILSL-VVSLV 182
+L + V +S+FTT L Y + P VT + S+ + L +++
Sbjct: 144 MLFSSVGLSSFTTILFFIGNHRMYQNYLRNHLQPWNVTGDSIRSYCEKFYLFPLKMITWT 203
Query: 183 LSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYIPY 242
+ +++ FI + LLI SL RH +K +GF P +AH+ A+ ++ F +L+I Y
Sbjct: 204 MPTAVFFICMI----LLITSLGRHRKKALLTTSGFREPSVQAHIKALLALLSFAMLFISY 259
Query: 243 SVATLVQYLPFYAGMDMG---TKSICLIFATLYSPGHSVLIIITHPKLKTTAK 292
++ + + +D +S+ + A + H ++++ ++ +L+ K
Sbjct: 260 FLSLVFSAAGIFPPLDFKFWVWESVIYLCAAV----HPIILLFSNCRLRAVLK 308
>gi|148235367 type 2 taste receptor member 30 [Homo sapiens]
Length = 319
Score = 94.4 bits (233), Expect = 1e-19
Identities = 79/300 (26%), Positives = 144/300 (48%), Gaps = 25/300 (8%)
Query: 7 FSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNT 66
FS +I V++ +G N FI +VN WVK +IS D+IL +L ++R +GL V
Sbjct: 9 FSILI--VVIFVIGNFANGFIALVNSIEWVKRQKISFVDQILTALAVSR---VGLLWVLL 63
Query: 67 IYFVSSNTERSVY-----LSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLL 121
+++ ++ + Y ++A+ V + + S W T L++ Y ++I NF + +FL +
Sbjct: 64 LHWYATQLNPAFYSVEVRITAYNV--WAVTNHFSSWLATSLSMFYLLRIANFSNLIFLRI 121
Query: 122 KRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRN---NTSFNI---SEGIL 175
KR + + +LL +L F C ++ E V T+ N ++ I S
Sbjct: 122 KRRVKSVVLVILLGPLL---FLVCHLFVINM----DETVWTKEYEGNVTWKIKLRSAMYH 174
Query: 176 SLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYF 235
S + +L++ + + + S LLI SL +H++KMQ + G +P T+ H+ A++ + F
Sbjct: 175 SNMTLTMLANFVPLTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVTSF 234
Query: 236 LILYIPYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
L+L Y ++ ++ F C Y H ++I+ + KLK +L
Sbjct: 235 LLLCAIYFLSMIISVCNFGRLEKQPVFMFCQAIIFSYPSTHPFILILGNKKLKQIFLSVL 294
>gi|28882035 taste receptor, type 2, member 19 [Homo sapiens]
Length = 299
Score = 92.4 bits (228), Expect = 4e-19
Identities = 76/295 (25%), Positives = 141/295 (47%), Gaps = 10/295 (3%)
Query: 7 FSAIIASVILNF---VGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFL 63
F II+S+++ F +G + N FI +VN WV + +ISS+++IL +L ++R +L + L
Sbjct: 4 FLLIISSILVVFAFVLGNVANGFIALVNVIDWVNTRKISSAEQILTALVVSRIGLLWVML 63
Query: 64 VNTIYFVSSNTERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKR 123
V ++ + + + + S+W L+I +KI NF + + L LK+
Sbjct: 64 FLWYATVFNSALYGLEVRIVASNAWAVTNHFSMWLAASLSIFCLLKIANFSNLISLHLKK 123
Query: 124 NISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNTSFNIS--EGI-LSLVVS 180
I + +LL L+ IT+ + E N ++ I I LS +
Sbjct: 124 RIKSVVLVILLG-PLVFLICNLAVITMDERVWTKEY---EGNVTWKIKLRNAIHLSSLTV 179
Query: 181 LVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLILYI 240
L++ + F +++ LLI SL +H++KM+ ++ G +P T+ H+ A++ + FL+L+
Sbjct: 180 TTLANLIPFTLSLICFLLLICSLCKHLKKMRLHSKGSQDPSTKVHIKALQTVTSFLMLFA 239
Query: 241 PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKIL 295
Y + + +C A +Y HS ++I+ KLK T +L
Sbjct: 240 IYFLCIITSTWNLRTQQSKLVLLLCQTVAIMYPSFHSFILIMGSRKLKQTFLSVL 294
>gi|8394395 taste receptor T2R16 [Homo sapiens]
Length = 291
Score = 79.7 bits (195), Expect = 3e-15
Identities = 66/251 (26%), Positives = 114/251 (45%), Gaps = 28/251 (11%)
Query: 10 IIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYF 69
+I V+ + I+ + I V + W++ R+ D IL SLGI+RF + ++N F
Sbjct: 11 MIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNN--F 68
Query: 70 VSSNTERSVYLSAFFVLCFM-----FLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRN 124
S Y + +VLC + F + + W +LL + YC+K+++F H +FL L+
Sbjct: 69 CS-------YFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWR 121
Query: 125 ISPKIPRLLLACVLI-------SAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSL 177
I P +LL ++I SA + I L P T + +
Sbjct: 122 ILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQAH 181
Query: 178 VVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYFLI 237
V+LV + FI+ + S L+ SL + I Q ++TG NP +A A++ + I
Sbjct: 182 TVALV----IPFILFLASTIFLMASLTKQI---QHHSTGHCNPSMKARFTALRSLAVLFI 234
Query: 238 LYIPYSVATLV 248
++ Y + L+
Sbjct: 235 VFTSYFLTILI 245
>gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo
sapiens]
Length = 1581
Score = 32.3 bits (72), Expect = 0.52
Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 24/146 (16%)
Query: 22 IMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSNTERS---- 77
IM LF+ +V T I S ++FSL FL+ GL LV + +S ++S
Sbjct: 279 IMALFLALVIRST---QFIILSGFMVVFSL----FLLYGLSLVALAFLMSILVKKSFLTG 331
Query: 78 --VYLSAFFVLCFMF------LDSSSVWFVTLLN-ILYCVKITNFQHSVFLLLKRNISPK 128
V+L F C F L +S W ++LL+ + + + H + L N P
Sbjct: 332 LVVFLLTVFWGCLGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYDL-NSNAFPH 390
Query: 129 IP---RLLLACVLISAFTTCLYITLS 151
L++A + AF TCLY+ L+
Sbjct: 391 PSDGSNLIVATNFMLAFDTCLYLALA 416
>gi|47271479 Na+/H+ exchanger domain containing 2 [Homo sapiens]
Length = 537
Score = 32.3 bits (72), Expect = 0.52
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 17/69 (24%)
Query: 129 IPRLLLAC------VLISAFTTCLYITLSQASPFPELVTTRNNTSFNISEGILSLVVSLV 182
+P LL+A + I+ F TCL I S S T FN+ G+L +V+ +
Sbjct: 267 VPTLLMAAGSFDDILAITGFNTCLGIAFSTGS-----------TVFNVLRGVLEVVIGVA 315
Query: 183 LSSSLQFII 191
S L F I
Sbjct: 316 TGSVLGFFI 324
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 32.0 bits (71), Expect = 0.68
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 20/115 (17%)
Query: 11 IASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFV 70
IA +++ + NL I V K KS+ ++ S++ +FSL ++ FL+ L L + V
Sbjct: 32 IAIIVITIFVCLGNLVIVVTLYK---KSYLLTLSNKFVFSLTLSNFLLSVLVLP---FVV 85
Query: 71 SSNTER----SVYLSAFFVLCFMFLDSSSV----------WFVTLLNILYCVKIT 111
+S+ R V F L ++ + S+S+ ++ L ++Y +KIT
Sbjct: 86 TSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKIT 140
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 30.8 bits (68), Expect = 1.5
Identities = 54/291 (18%), Positives = 122/291 (41%), Gaps = 26/291 (8%)
Query: 14 VILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFVSSN 73
+++ G++ NL + C++ +S R + ++ + +L ++ FLM F ++F SS
Sbjct: 78 LLVGLTGMLGNLTVIYTFCRS--RSLR-TPANMFIINLAVSDFLMS--FTQAPVFFTSSL 132
Query: 74 TERSVYLSA---FFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIP 130
++ ++ F+ C SS+ +T + + + IT + + KR +
Sbjct: 133 YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAA---- 188
Query: 131 RLLLACVLISAFTTCLYITLSQASPFPE-LVTTRNNTSFNISEGILSLVVSLV-LSSSLQ 188
+L V + A L ++ PE L+T+ + + + + + + L L
Sbjct: 189 -FVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLP 247
Query: 189 FIINVTSASLLIHSLRRHIQKMQK------NATGFWNPQT-EAHVGAMKLMVYFLILYI- 240
+I + + ++R + +Q N W Q ++ K+M+ ++L++
Sbjct: 248 LLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVL 307
Query: 241 ---PYSVATLVQYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLK 288
PYS LV + + + S+ + A + + ++ ITHPK +
Sbjct: 308 SWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 358
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 30.8 bits (68), Expect = 1.5
Identities = 52/258 (20%), Positives = 105/258 (40%), Gaps = 35/258 (13%)
Query: 4 LFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRI-LFSLGITRFLMLGLF 62
+ + S + IL VG + L++ +++ H+ + + L L + + +
Sbjct: 32 MLFASFYLLDFILALVGNTLALWL-------FIRDHKSGTPANVFLMHLAVADLSCVLVL 84
Query: 63 LVNTIYFVSSNT----ERSVYLSAFFVLCFMFLDSSSVWFVTLLNILYCVKITNFQHSVF 118
+Y S N E + L+ F M+ +S++F+T C+ F V
Sbjct: 85 PTRLVYHFSGNHWPFGEIACRLTGFLFYLNMY---ASIYFLT------CISADRFLAIVH 135
Query: 119 LLLKRNISPKIPRLLLACVLISAFTTCLYITLSQASPFPELVTTRNNT---SFNISEGIL 175
+ S K+ R L A + + + + ++ P+ V T + +
Sbjct: 136 PVK----SLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASH 191
Query: 176 SLVVSLVLSSSLQFIINVTSASLLIHSLRRHIQKMQKNATGFWNPQTEAHVGAMKLMVYF 235
+VSL ++ + FI VT L+I SLR+ + +++K +T+A ++ F
Sbjct: 192 HALVSLAVAFTFPFITTVTCYLLIIRSLRQGL-RVEKRL------KTKAVRMIAIVLAIF 244
Query: 236 LILYIPYSVATLVQYLPF 253
L+ ++PY V V L +
Sbjct: 245 LVCFVPYHVNRSVYVLHY 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.140 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,093,115
Number of Sequences: 37866
Number of extensions: 335175
Number of successful extensions: 1213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1123
Number of HSP's gapped (non-prelim): 63
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.