Guide to the Human Genome
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Search of human proteins with 83699414

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83699414 beta-defensin 130 [Homo sapiens]
         (79 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo sapiens]   172   7e-44
gi|83699414 beta-defensin 130 [Homo sapiens]                          172   7e-44
gi|169202991 PREDICTED: similar to beta-defensin 130 [Homo sapiens]   164   2e-41
gi|169203490 PREDICTED: similar to beta-defensin 130 [Homo sapiens]   164   2e-41
gi|113422487 PREDICTED: similar to beta-defensin 130 [Homo sapiens]   164   2e-41
gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]   163   3e-41
gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo ...   163   3e-41
gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo ...   163   3e-41
gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo ...    82   1e-16
gi|239743480 PREDICTED: hypothetical protein XP_002342858 [Homo ...    80   4e-16
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ...    78   1e-15
gi|8923890 defensin, beta 103A precursor [Homo sapiens]                35   0.013
gi|125656159 beta-defensin 103B precursor [Homo sapiens]               35   0.013
gi|22748611 defensin, beta 106A precursor [Homo sapiens]               32   0.084
gi|103485143 defensin, beta 106B precursor [Homo sapiens]              32   0.084
gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]              31   0.19 
gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]              31   0.19 
gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]               31   0.19 
gi|110825974 ADAM metallopeptidase with thrombospondin type 1 mo...    28   1.6  
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]              27   2.7  
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]              27   2.7  
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]              27   2.7  
gi|46409558 beta-defensin 32 precursor [Homo sapiens]                  27   3.5  
gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo ...    26   6.0  
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]             26   6.0  

>gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 79

 Score =  172 bits (435), Expect = 7e-44
 Identities = 79/79 (100%), Positives = 79/79 (100%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60

Query: 61 RRWWILEPYPTPVPKGKSP 79
          RRWWILEPYPTPVPKGKSP
Sbjct: 61 RRWWILEPYPTPVPKGKSP 79


>gi|83699414 beta-defensin 130 [Homo sapiens]
          Length = 79

 Score =  172 bits (435), Expect = 7e-44
 Identities = 79/79 (100%), Positives = 79/79 (100%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60

Query: 61 RRWWILEPYPTPVPKGKSP 79
          RRWWILEPYPTPVPKGKSP
Sbjct: 61 RRWWILEPYPTPVPKGKSP 79


>gi|169202991 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score =  164 bits (414), Expect = 2e-41
 Identities = 78/79 (98%), Positives = 78/79 (98%), Gaps = 1/79 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK C
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK-C 59

Query: 61 RRWWILEPYPTPVPKGKSP 79
          RRWWILEPYPTPVPKGKSP
Sbjct: 60 RRWWILEPYPTPVPKGKSP 78


>gi|169203490 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score =  164 bits (414), Expect = 2e-41
 Identities = 78/79 (98%), Positives = 78/79 (98%), Gaps = 1/79 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK C
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK-C 59

Query: 61 RRWWILEPYPTPVPKGKSP 79
          RRWWILEPYPTPVPKGKSP
Sbjct: 60 RRWWILEPYPTPVPKGKSP 78


>gi|113422487 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score =  164 bits (414), Expect = 2e-41
 Identities = 78/79 (98%), Positives = 78/79 (98%), Gaps = 1/79 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK C
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKK-C 59

Query: 61 RRWWILEPYPTPVPKGKSP 79
          RRWWILEPYPTPVPKGKSP
Sbjct: 60 RRWWILEPYPTPVPKGKSP 78


>gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]
          Length = 128

 Score =  163 bits (412), Expect = 3e-41
 Identities = 77/79 (97%), Positives = 77/79 (97%), Gaps = 1/79 (1%)

Query: 2   KLHSLISVLLLFVTLIPKGK-TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
           KLHSLISVLLLFVTLIPK K TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC
Sbjct: 50  KLHSLISVLLLFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 109

Query: 61  RRWWILEPYPTPVPKGKSP 79
           RRWWILEPYPTPVPKGKSP
Sbjct: 110 RRWWILEPYPTPVPKGKSP 128


>gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo
           sapiens]
          Length = 128

 Score =  163 bits (412), Expect = 3e-41
 Identities = 77/79 (97%), Positives = 77/79 (97%), Gaps = 1/79 (1%)

Query: 2   KLHSLISVLLLFVTLIPKGK-TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
           KLHSLISVLLLFVTLIPK K TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC
Sbjct: 50  KLHSLISVLLLFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 109

Query: 61  RRWWILEPYPTPVPKGKSP 79
           RRWWILEPYPTPVPKGKSP
Sbjct: 110 RRWWILEPYPTPVPKGKSP 128


>gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo
           sapiens]
          Length = 128

 Score =  163 bits (412), Expect = 3e-41
 Identities = 77/79 (97%), Positives = 77/79 (97%), Gaps = 1/79 (1%)

Query: 2   KLHSLISVLLLFVTLIPKGK-TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
           KLHSLISVLLLFVTLIPK K TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC
Sbjct: 50  KLHSLISVLLLFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 109

Query: 61  RRWWILEPYPTPVPKGKSP 79
           RRWWILEPYPTPVPKGKSP
Sbjct: 110 RRWWILEPYPTPVPKGKSP 128


>gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo
          sapiens]
          Length = 87

 Score = 81.6 bits (200), Expect = 1e-16
 Identities = 34/73 (46%), Positives = 45/73 (61%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          M+LH L+ +LL  + L P  K G+ P +  C+ L GVCR  +C  ++D IG C    KCC
Sbjct: 1  MRLHLLLLILLFSILLSPGNKGGLGPAEGHCLNLSGVCRRDVCKVVEDQIGACRRKMKCC 60

Query: 61 RRWWILEPYPTPV 73
          R WWIL P PTP+
Sbjct: 61 RAWWILMPIPTPL 73


>gi|239743480 PREDICTED: hypothetical protein XP_002342858 [Homo
          sapiens]
          Length = 87

 Score = 80.1 bits (196), Expect = 4e-16
 Identities = 34/73 (46%), Positives = 47/73 (64%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          M+LH L+ +LLLF  L+   + G+ P +  C+ L GVCR  +C+ ++D IG C    KCC
Sbjct: 1  MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCC 60

Query: 61 RRWWILEPYPTPV 73
          R WWIL P PTP+
Sbjct: 61 RAWWILMPIPTPL 73


>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
           sapiens]
          Length = 192

 Score = 78.2 bits (191), Expect = 1e-15
 Identities = 32/73 (43%), Positives = 46/73 (63%)

Query: 1   MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
           ++LH L+ +LLLF  L+   +  + P +  C++L GVCR  +C  ++D IG C    KCC
Sbjct: 64  VRLHVLLLILLLFSILLSPVRGALGPAEVHCLSLSGVCRRDVCKVVEDQIGACRRRMKCC 123

Query: 61  RRWWILEPYPTPV 73
           R WWIL P PTP+
Sbjct: 124 RAWWILMPIPTPL 136


>gi|8923890 defensin, beta 103A precursor [Homo sapiens]
          Length = 67

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 5/66 (7%)

Query: 1  MKLHSLISVLLLFVTLIP-KGKTGVIPGQKQ--CIALKGVCRDKLCSTLDDTIGICN-EG 56
          M++H L+  LL F+ L+P  G  G+I   ++  C    G C    C   ++ IG C+  G
Sbjct: 1  MRIHYLLFALL-FLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRG 59

Query: 57 KKCCRR 62
          +KCCRR
Sbjct: 60 RKCCRR 65


>gi|125656159 beta-defensin 103B precursor [Homo sapiens]
          Length = 67

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 5/66 (7%)

Query: 1  MKLHSLISVLLLFVTLIP-KGKTGVIPGQKQ--CIALKGVCRDKLCSTLDDTIGICN-EG 56
          M++H L+  LL F+ L+P  G  G+I   ++  C    G C    C   ++ IG C+  G
Sbjct: 1  MRIHYLLFALL-FLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRG 59

Query: 57 KKCCRR 62
          +KCCRR
Sbjct: 60 RKCCRR 65


>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score = 32.3 bits (72), Expect = 0.084
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 29 KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 61
          ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 24 EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score = 32.3 bits (72), Expect = 0.084
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 29 KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 61
          ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 24 EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55


>gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +    C
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTKLNANC 59


>gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +    C
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTKLNANC 59


>gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]
          Length = 61

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +    C
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTKLNANC 59


>gi|110825974 ADAM metallopeptidase with thrombospondin type 1 motif,
            2 isoform 1 preproprotein [Homo sapiens]
          Length = 1211

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)

Query: 39   RDKLCSTLDDTIGICNEGKKCCRRWWILEPYPTPV--PKGKS 78
            R  LC T DD+ GIC E +    R   L P P  +  P  KS
Sbjct: 998  RPVLCRTADDSFGICQEERPETARTCRLGPCPRNISDPSKKS 1039


>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/39 (35%), Positives = 17/39 (43%), Gaps = 1/39 (2%)

Query: 22 TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          + V   QK C  +KG CR K C   +     C  G  CC
Sbjct: 9  SSVCRSQKSCWIIKGHCR-KNCKPGEQVKKPCKNGDYCC 46


>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/39 (35%), Positives = 17/39 (43%), Gaps = 1/39 (2%)

Query: 22 TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          + V   QK C  +KG CR K C   +     C  G  CC
Sbjct: 9  SSVCRSQKSCWIIKGHCR-KNCKPGEQVKKPCKNGDYCC 46


>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/39 (35%), Positives = 17/39 (43%), Gaps = 1/39 (2%)

Query: 22 TGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          + V   QK C  +KG CR K C   +     C  G  CC
Sbjct: 9  SSVCRSQKSCWIIKGHCR-KNCKPGEQVKKPCKNGDYCC 46


>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
          Length = 95

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)

Query: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
          MK   L+   L F+T +     G   G K      G CR   C   +  + +CN  +KCC
Sbjct: 1  MKFLLLVLAALGFLTQVIPASAG---GSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56


>gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo
           sapiens]
          Length = 316

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 9/17 (52%), Positives = 10/17 (58%)

Query: 60  CRRWWILEPYPTPVPKG 76
           CR  W+L P P P P G
Sbjct: 229 CRSRWVLAPPPPPAPPG 245


>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
          Length = 4116

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 9/46 (19%)

Query: 39   RDKLCSTLDDTIGICNEGKKCCRRWWIL---------EPYPTPVPK 75
            +DKL  +L  TIGI  + K+     W            PYP P P+
Sbjct: 3368 KDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQ 3413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.143    0.484 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,934,783
Number of Sequences: 37866
Number of extensions: 175213
Number of successful extensions: 325
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 306
Number of HSP's gapped (non-prelim): 25
length of query: 79
length of database: 18,247,518
effective HSP length: 51
effective length of query: 28
effective length of database: 16,316,352
effective search space: 456857856
effective search space used: 456857856
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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