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Search of human proteins with 81230487
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|81230487 acyl-CoA thioesterase 6 [Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|81230487 acyl-CoA thioesterase 6 [Homo sapiens] 429 e-121
gi|148727286 acyl-CoA thioesterase 2 [Homo sapiens] 264 5e-71
gi|81230485 acyl-CoA thioesterase 1 [Homo sapiens] 261 4e-70
gi|187761341 acyl-CoA thioesterase 4 [Homo sapiens] 230 6e-61
gi|189083866 bile acid Coenzyme A: amino acid N-acyltransferase ... 114 4e-26
gi|4502351 bile acid Coenzyme A: amino acid N-acyltransferase [H... 114 4e-26
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 30 1.4
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 30 1.4
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 29 2.5
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 29 2.5
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 29 2.5
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 29 2.5
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 29 2.5
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 29 2.5
gi|108773804 Fraser syndrome 1 [Homo sapiens] 28 4.2
gi|47132591 protein kinase N1 isoform 1 [Homo sapiens] 28 5.5
gi|47132589 protein kinase N1 isoform 2 [Homo sapiens] 28 5.5
>gi|81230487 acyl-CoA thioesterase 6 [Homo sapiens]
Length = 207
Score = 429 bits (1103), Expect = e-121
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK
Sbjct: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY
Sbjct: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA
Sbjct: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
Query: 181 QVDAWQQIQTFFHKHLNGKKSVKHSKI 207
QVDAWQQIQTFFHKHLNGKKSVKHSKI
Sbjct: 181 QVDAWQQIQTFFHKHLNGKKSVKHSKI 207
>gi|148727286 acyl-CoA thioesterase 2 [Homo sapiens]
Length = 483
Score = 264 bits (674), Expect = 5e-71
Identities = 120/207 (57%), Positives = 157/207 (75%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
+L HP+VKGP + LLG SKGG+LCLSMASFLKGITA V+IN VAN LHYK +P
Sbjct: 277 LLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGETLPP 336
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
+ + ++K+TK G+ +D ++PLE + +S +P+E+A+ FLF+VG DD +WKSEFY
Sbjct: 337 VGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFY 396
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
A A +RLQAHG+ +PQIICYPETGH I+PPYFP RAS+HA++G I +GGEP+AH+ A
Sbjct: 397 ANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMA 456
Query: 181 QVDAWQQIQTFFHKHLNGKKSVKHSKI 207
QVDAW+Q+QTFFHKHL G + SK+
Sbjct: 457 QVDAWKQLQTFFHKHLGGHEGTIPSKV 483
>gi|81230485 acyl-CoA thioesterase 1 [Homo sapiens]
Length = 421
Score = 261 bits (666), Expect = 4e-70
Identities = 119/207 (57%), Positives = 156/207 (75%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
+L HP+VKGP + LLG SKGG+LCLSMASFLKGITA V+IN VAN L YK +P
Sbjct: 215 LLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPP 274
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
+ + ++K+TK G+ +D ++PLE + +S +P+E+A+ FLF+VG DD +WKSEFY
Sbjct: 275 VGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFY 334
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
A A +RLQAHG+ +PQIICYPETGH I+PPYFP RAS+HA++G I +GGEP+AH+ A
Sbjct: 335 ANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMA 394
Query: 181 QVDAWQQIQTFFHKHLNGKKSVKHSKI 207
QVDAW+Q+QTFFHKHL G + SK+
Sbjct: 395 QVDAWKQLQTFFHKHLGGHEGTIPSKV 421
>gi|187761341 acyl-CoA thioesterase 4 [Homo sapiens]
Length = 421
Score = 230 bits (587), Expect = 6e-61
Identities = 112/207 (54%), Positives = 144/207 (69%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
MLQHP+VKGP I LLG S G D+CLSMASFLK ++ATV IN + ++YK IP
Sbjct: 215 MLQHPQVKGPGIGLLGISLGADICLSMASFLKNVSATVSINGSGISGNTAINYKHSSIPP 274
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
L DL ++K+ SG + +D + + + + S++P+EKAQ P L IVG DD +W+SE Y
Sbjct: 275 LGYDLRRIKVAFSGLVDIVDIRNALVGGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELY 334
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
AQ SERLQAHGKE+PQIICYP TGH I+PPYFP AS+H +L + + +GGEP+AHSKA
Sbjct: 335 AQTVSERLQAHGKEKPQIICYPGTGHYIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKA 394
Query: 181 QVDAWQQIQTFFHKHLNGKKSVKHSKI 207
Q DAW+QI FF KHL G + K+
Sbjct: 395 QEDAWKQILAFFCKHLGGTQKTAVPKL 421
>gi|189083866 bile acid Coenzyme A: amino acid N-acyltransferase
[Homo sapiens]
Length = 418
Score = 114 bits (286), Expect = 4e-26
Identities = 73/196 (37%), Positives = 102/196 (52%), Gaps = 3/196 (1%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
+L+HPKV G + ++ +G + LSMA +LK +TATVLIN P Y I
Sbjct: 218 LLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQP 277
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
L + G L T+ + Q L P+E+AQ FLFIVG D++ S+ +
Sbjct: 278 LPHSAQLISTNALGLLELYRTFETT-QVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAH 336
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
A+ A +L+ HGK ++ YP GH I+PPY P AS L + +GGE H+ A
Sbjct: 337 AEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDL--RLHWGGEVIPHAAA 394
Query: 181 QVDAWQQIQTFFHKHL 196
Q AW++IQ F KHL
Sbjct: 395 QEHAWKEIQRFLRKHL 410
>gi|4502351 bile acid Coenzyme A: amino acid N-acyltransferase [Homo
sapiens]
Length = 418
Score = 114 bits (286), Expect = 4e-26
Identities = 73/196 (37%), Positives = 102/196 (52%), Gaps = 3/196 (1%)
Query: 1 MLQHPKVKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
+L+HPKV G + ++ +G + LSMA +LK +TATVLIN P Y I
Sbjct: 218 LLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQP 277
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFY 120
L + G L T+ + Q L P+E+AQ FLFIVG D++ S+ +
Sbjct: 278 LPHSAQLISTNALGLLELYRTFETT-QVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAH 336
Query: 121 AQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKA 180
A+ A +L+ HGK ++ YP GH I+PPY P AS L + +GGE H+ A
Sbjct: 337 AEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDL--RLHWGGEVIPHAAA 394
Query: 181 QVDAWQQIQTFFHKHL 196
Q AW++IQ F KHL
Sbjct: 395 QEHAWKEIQRFLRKHL 410
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 30.0 bits (66), Expect = 1.4
Identities = 16/45 (35%), Positives = 23/45 (51%)
Query: 16 GFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
GFSK + +S A FL G+ V + +A LHY D + P+
Sbjct: 376 GFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 420
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 30.0 bits (66), Expect = 1.4
Identities = 16/45 (35%), Positives = 23/45 (51%)
Query: 16 GFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
GFSK + +S A FL G+ V + +A LHY D + P+
Sbjct: 376 GFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 420
>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
sapiens]
Length = 828
Score = 29.3 bits (64), Expect = 2.5
Identities = 14/48 (29%), Positives = 20/48 (41%)
Query: 131 HGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHS 178
H P I +P PP PP+ S+H ++ +I P HS
Sbjct: 51 HPPTHPSIHTHPPIHPHTHPPIHPPTHPSIHPLIHPSIHPSLHPPTHS 98
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 29.3 bits (64), Expect = 2.5
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 15/116 (12%)
Query: 69 KITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERL 128
KI + + M+T + PL+E S +E+ + +D SE ++ + E
Sbjct: 1545 KINRMDIVHLMETNTEPLQERISHSYAEIEQT-------ITLD----HSEGFSVLQEELC 1593
Query: 129 QAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDA 184
A K++ + E+ C PP SV G + F G PK + A
Sbjct: 1594 TAQHKQKEEQAVSKESETCDHPPIVSEEDISV----GYSTFQDGVPKTEGDSSATA 1645
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 29.3 bits (64), Expect = 2.5
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 15/116 (12%)
Query: 69 KITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERL 128
KI + + M+T + PL+E S +E+ + +D SE ++ + E
Sbjct: 1554 KINRMDIVHLMETNTEPLQERISHSYAEIEQT-------ITLD----HSEGFSVLQEELC 1602
Query: 129 QAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDA 184
A K++ + E+ C PP SV G + F G PK + A
Sbjct: 1603 TAQHKQKEEQAVSKESETCDHPPIVSEEDISV----GYSTFQDGVPKTEGDSSATA 1654
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 29.3 bits (64), Expect = 2.5
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 15/116 (12%)
Query: 69 KITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERL 128
KI + + M+T + PL+E S +E+ + +D SE ++ + E
Sbjct: 3639 KINRMDIVHLMETNTEPLQERISHSYAEIEQT-------ITLD----HSEGFSVLQEELC 3687
Query: 129 QAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDA 184
A K++ + E+ C PP SV G + F G PK + A
Sbjct: 3688 TAQHKQKEEQAVSKESETCDHPPIVSEEDISV----GYSTFQDGVPKTEGDSSATA 3739
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 54 KDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVP 96
KD I PKL D G V I + FL ++ + NP + S P
Sbjct: 717 KDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAP 759
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 54 KDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVP 96
KD I PKL D G V I + FL ++ + NP + S P
Sbjct: 755 KDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAP 797
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 28.5 bits (62), Expect = 4.2
Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 9/101 (8%)
Query: 3 QHPKVKGPS--IALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPK 60
Q+P ++G + L ++G +L K A + IN + + KD+++ K
Sbjct: 2878 QYPVIEGLETFVVFLSSAQGAELT-------KPFQAVIAINDTFQDVPSMQFAKDLLLVK 2930
Query: 61 LVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQ 101
+ + V IT+SG L++ + + H+ Q + E+ Q
Sbjct: 2931 EKEGVLHVPITRSGDLSYESSVRCYTQSHSAQVMEDFEERQ 2971
>gi|47132591 protein kinase N1 isoform 1 [Homo sapiens]
Length = 948
Score = 28.1 bits (61), Expect = 5.5
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 14 LLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLH-----YKDMIIPK-LVDDLGK 67
++ +S GGDL L + S + + +ACV + LH Y+D+ + L+D G
Sbjct: 700 VMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGY 759
Query: 68 VKITKSG 74
VKI G
Sbjct: 760 VKIADFG 766
>gi|47132589 protein kinase N1 isoform 2 [Homo sapiens]
Length = 942
Score = 28.1 bits (61), Expect = 5.5
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 14 LLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLH-----YKDMIIPK-LVDDLGK 67
++ +S GGDL L + S + + +ACV + LH Y+D+ + L+D G
Sbjct: 694 VMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGY 753
Query: 68 VKITKSG 74
VKI G
Sbjct: 754 VKIADFG 760
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,718,169
Number of Sequences: 37866
Number of extensions: 371118
Number of successful extensions: 782
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 760
Number of HSP's gapped (non-prelim): 23
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.