Guide to the Human Genome
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Search of human proteins with 7706509

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706509 beta-ureidopropionase [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706509 beta-ureidopropionase [Homo sapiens]                       789   0.0  
gi|5031947 nitrilase 1 [Homo sapiens]                                  63   4e-10
gi|9910460 nitrilase family, member 2 [Homo sapiens]                   50   4e-06
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi...    30   2.8  
gi|114205410 hypothetical protein LOC51059 [Homo sapiens]              30   2.8  
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...    30   3.7  
gi|4557373 biotinidase precursor [Homo sapiens]                        30   3.7  
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept...    30   4.8  
gi|17865816 vanin 2 isoform 2 [Homo sapiens]                           30   4.8  
gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]                 30   4.8  
gi|193083139 leucine rich repeat containing 32 precursor [Homo s...    30   4.8  
gi|5031707 leucine rich repeat containing 32 precursor [Homo sap...    30   4.8  
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa...    29   6.2  

>gi|7706509 beta-ureidopropionase [Homo sapiens]
          Length = 384

 Score =  789 bits (2038), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE 60
           MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
Sbjct: 1   MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE 60

Query: 61  AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA 120
           AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
Sbjct: 61  AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA 120

Query: 121 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT 180
           WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT
Sbjct: 121 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT 180

Query: 181 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL 240
           AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL
Sbjct: 181 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL 240

Query: 241 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS 300
           NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS
Sbjct: 241 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS 300

Query: 301 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG 360
           GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG
Sbjct: 301 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG 360

Query: 361 RYEMYARELAEAVKSNYSPTIVKE 384
           RYEMYARELAEAVKSNYSPTIVKE
Sbjct: 361 RYEMYARELAEAVKSNYSPTIVKE 384


>gi|5031947 nitrilase 1 [Homo sapiens]
          Length = 327

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 57/188 (30%), Positives = 82/188 (43%), Gaps = 23/188 (12%)

Query: 169 RDSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNESTYYMEG-NLGHPVFQ 222
           +D E    ++N  V++++ GAV+   RK H     IP  G   ES   M G +L  PV  
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPV-S 192

Query: 223 TQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCF 282
           T  G+I + +CY    P   L  +  GAEI+  PSA       + W +  R  AI   C+
Sbjct: 193 TPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCY 252

Query: 283 TCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKL 342
             A  + G  H          K+A       YG S V  P  +     S    GL +A++
Sbjct: 253 VVAAAQCGRHH---------EKRAS------YGHSMVVDPWGTVVARCSEG-PGLCLARI 296

Query: 343 DLNLCQQV 350
           DLN  +Q+
Sbjct: 297 DLNYLRQL 304


>gi|9910460 nitrilase family, member 2 [Homo sapiens]
          Length = 276

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 14/189 (7%)

Query: 99  RIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNH 158
           R  + +  AA  G  I+   E +  P+         + E+AE    G +T+   ++AK  
Sbjct: 23  RACSFIREAATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKEC 76

Query: 159 DMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNESTYYME 213
            + ++   +    E    L+NT  V    G +L K RK H     +P    F ES     
Sbjct: 77  SIYLIGGSIPE--EDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSP 134

Query: 214 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR 273
           G+     F T + R+ + ICY         +Y+  G +++  P A       + W +  R
Sbjct: 135 GD-SFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQR 193

Query: 274 NAAIANHCF 282
           + A+ N  +
Sbjct: 194 SRAVDNQVY 202


>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo
           sapiens]
          Length = 887

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 15/38 (39%), Positives = 17/38 (44%)

Query: 278 ANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYG 315
           A +C    I  VG  H  N   +  GK  H DFGY  G
Sbjct: 730 AGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILG 767


>gi|114205410 hypothetical protein LOC51059 [Homo sapiens]
          Length = 1406

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 132 KLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERD----SEHGDVLWNTAV--VIS 185
           +LP TE    A +   ++ C +L   ++   ++  + +D    + H   LW   +  V  
Sbjct: 268 ELPHTELEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTL 327

Query: 186 NSGAVLGKTRKNHIPRVGDFNESTYYME 213
           +S      T+++H  RV  F+E+ +YME
Sbjct: 328 HSQVTTYLTQEHHTLRVRRFSEAFFYME 355


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
           sapiens]
          Length = 1044

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 8/74 (10%)

Query: 250 AEIIFNPSATIGALSESLWPIEARNAAIANHCFTCA-------INRVGTEHFPNEFTSGD 302
           A   FN  A +  L +S  P EA + AI     +CA       +  +G  H  N      
Sbjct: 846 ATAAFNKDALLNWL-KSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES 904

Query: 303 GKKAHQDFGYFYGS 316
           G+  H DFG+F G+
Sbjct: 905 GQLFHIDFGHFLGN 918


>gi|4557373 biotinidase precursor [Homo sapiens]
          Length = 543

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 29/155 (18%)

Query: 104 VEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAE--------------DGPTTR 149
           V  AA   V II F E     F F      P+ +F  S +              D    +
Sbjct: 97  VMTAAQKDVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEVLQ 156

Query: 150 FCQKLAKNHDMVVVSPILERDSEH---------GDVLWNTAVVISNSGAVLGKTRKNHIP 200
               +A   DM +V+ +  ++  H         G   +NT VV SN+G ++ + RK+++ 
Sbjct: 157 RLSCMAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNL- 215

Query: 201 RVGDFNESTYYMEGNLGHPVFQTQF-GRIAVNICY 234
               + E+ + +   +    F T F GR  +  C+
Sbjct: 216 ----YFEAAFDVPLKVDLITFDTPFAGRFGIFTCF 246


>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
           [Homo sapiens]
          Length = 1068

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 270 IEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYF 313
           I+    + A +C    I  +G  H  N     DG+  H DFG+F
Sbjct: 894 IDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHF 937


>gi|17865816 vanin 2 isoform 2 [Homo sapiens]
          Length = 467

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 154 LAKNHDMVVVS------PILERDSE---HGDVLWNTAVVISNSGAVLGKTRKNHIPRVGD 204
           LAK++ + V++      P   RDS    +G   +NT VV +  G ++ +  K H+     
Sbjct: 75  LAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGKLVARYHKYHL----- 129

Query: 205 FNESTYYMEGNLGHPVFQTQFGRIAVNICY 234
           ++E  + +        F T FGR  +  C+
Sbjct: 130 YSEPQFNVPEKPELVTFNTAFGRFGIFTCF 159


>gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]
          Length = 520

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 154 LAKNHDMVVVS------PILERDSE---HGDVLWNTAVVISNSGAVLGKTRKNHIPRVGD 204
           LAK++ + V++      P   RDS    +G   +NT VV +  G ++ +  K H+     
Sbjct: 128 LAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGKLVARYHKYHL----- 182

Query: 205 FNESTYYMEGNLGHPVFQTQFGRIAVNICY 234
           ++E  + +        F T FGR  +  C+
Sbjct: 183 YSEPQFNVPEKPELVTFNTAFGRFGIFTCF 212


>gi|193083139 leucine rich repeat containing 32 precursor [Homo
           sapiens]
          Length = 662

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 32  KELRKLDLPR---EAFEAASREDFELQGYAFEAAEEQLRR-------PRIVHVGLVQNRI 81
           ++LR LDL     EAF+ AS+   E Q    +  E +L         PR++++ L  N I
Sbjct: 218 QQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLI 277

Query: 82  PLPANAP 88
            LP   P
Sbjct: 278 RLPTGPP 284


>gi|5031707 leucine rich repeat containing 32 precursor [Homo
           sapiens]
          Length = 662

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 32  KELRKLDLPR---EAFEAASREDFELQGYAFEAAEEQLRR-------PRIVHVGLVQNRI 81
           ++LR LDL     EAF+ AS+   E Q    +  E +L         PR++++ L  N I
Sbjct: 218 QQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLI 277

Query: 82  PLPANAP 88
            LP   P
Sbjct: 278 RLPTGPP 284


>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
           sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 13/40 (32%), Positives = 18/40 (45%)

Query: 278 ANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSS 317
           A +C  C + +V   H  N     +G   H DFG+   SS
Sbjct: 670 AGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSS 709


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,727,014
Number of Sequences: 37866
Number of extensions: 641340
Number of successful extensions: 1263
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1254
Number of HSP's gapped (non-prelim): 14
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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