Guide to the Human Genome
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Search of human proteins with 14042943

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14042943 TatD DNase domain containing 1 isoform a [Homo
sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14042943 TatD DNase domain containing 1 isoform a [Homo sapiens]   613   e-176
gi|225903439 TatD DNase domain containing 1 isoform b [Homo sapi...   520   e-148
gi|225903424 TatD DNase domain containing 2 [Homo sapiens]             69   4e-12
gi|110349730 TatD DNase domain containing 3 isoform 1 [Homo sapi...    69   4e-12
gi|110349734 TatD DNase domain containing 3 isoform 2 [Homo sapi...    66   4e-11
gi|226061853 TatD DNase domain containing 3 isoform 5 [Homo sapi...    64   2e-10
gi|226061595 TatD DNase domain containing 3 isoform 3 [Homo sapi...    61   1e-09
gi|226061614 TatD DNase domain containing 3 isoform 4 [Homo sapi...    48   1e-05
gi|157671947 hypothetical protein LOC79974 isoform 2 [Homo sapiens]    30   3.3  
gi|157671945 hypothetical protein LOC79974 isoform 1 [Homo sapiens]    30   3.3  
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    29   4.4  
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         29   4.4  
gi|145309330 zinc finger protein 792 [Homo sapiens]                    29   4.4  
gi|4507157 sortilin-related receptor containing LDLR class A rep...    28   7.4  

>gi|14042943 TatD DNase domain containing 1 isoform a [Homo sapiens]
          Length = 297

 Score =  613 bits (1582), Expect = e-176
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MSRFKFIDIGINLTDPMFRGIYRGVQKHQDDLQDVIGRAVEIGVKKFMITGGNLQDSKDA 60
           MSRFKFIDIGINLTDPMFRGIYRGVQKHQDDLQDVIGRAVEIGVKKFMITGGNLQDSKDA
Sbjct: 1   MSRFKFIDIGINLTDPMFRGIYRGVQKHQDDLQDVIGRAVEIGVKKFMITGGNLQDSKDA 60

Query: 61  LHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRL 120
           LHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRL
Sbjct: 61  LHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRL 120

Query: 121 QFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTK 180
           QFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTK
Sbjct: 121 QFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTK 180

Query: 181 EAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRT 240
           EAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRT
Sbjct: 181 EAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRT 240

Query: 241 AFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVFFPGI 297
           AFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVFFPGI
Sbjct: 241 AFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVFFPGI 297


>gi|225903439 TatD DNase domain containing 1 isoform b [Homo
           sapiens]
          Length = 250

 Score =  520 bits (1339), Expect = e-148
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 48  MITGGNLQDSKDALHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKV 107
           MITGGNLQDSKDALHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKV
Sbjct: 1   MITGGNLQDSKDALHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKV 60

Query: 108 VAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDR 167
           VAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDR
Sbjct: 61  VAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDR 120

Query: 168 CVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCG 227
           CVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCG
Sbjct: 121 CVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCG 180

Query: 228 VKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYN 287
           VKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYN
Sbjct: 181 VKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYN 240

Query: 288 NTIKVFFPGI 297
           NTIKVFFPGI
Sbjct: 241 NTIKVFFPGI 250


>gi|225903424 TatD DNase domain containing 2 [Homo sapiens]
          Length = 761

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 69  MFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQ 128
           + +   GCHP     + ++     L+ L +       K VA GE GLD+      P   Q
Sbjct: 556 LVWGAFGCHPHFARYYSESQERNLLQALRH------PKAVAFGEMGLDYSYKCTTPVPEQ 609

Query: 129 LKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALID 188
            K FE+Q +L+   K P+ +HCR +  + L+IMK+          H F G+      L+ 
Sbjct: 610 HKVFERQLQLAVSLKKPLVIHCREADEDLLEIMKKFVPPDYKIHRHCFTGSYPVIEPLLK 669

Query: 189 L--DLYIGFNGCSLKTEA--NLEVLKSIPSEKLMIETDAPW 225
              ++ +GF      + A    E L+ IP E++++ETDAP+
Sbjct: 670 YFPNMSVGFTAVLTYSSAWEAREALRQIPLERIIVETDAPY 710


>gi|110349730 TatD DNase domain containing 3 isoform 1 [Homo
           sapiens]
          Length = 274

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 63/271 (23%), Positives = 123/271 (45%), Gaps = 36/271 (13%)

Query: 31  DLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQT-NGMFFSTVGCHPTRCGEFEKNNP 89
           DL DV+ +A +  V   +    +  + +  + L++  NG     +G HP + G   ++  
Sbjct: 23  DLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQ-GLPPEDQR 81

Query: 90  DLYLKEL---LNLAENNKGKVVAIGECGLDFDRLQFC----PKDTQLKYFEKQFELSEQT 142
            + LK+L   L + EN K +++AIGE GLDF   +F      K+ Q +   +Q +L+++ 
Sbjct: 82  SVTLKDLDVALPIIENYKDRLLAIGEVGLDFSP-RFAGTGEQKEEQRQVLIRQIQLAKRL 140

Query: 143 KLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKT 202
            LP+ +H R++    +++++      V  ++H+FDG    A   +    +       +++
Sbjct: 141 NLPVNVHSRSAGRPTINLLQEQGAEKV--LLHAFDGRPSVAMEGVRAGYFFSIPPSIIRS 198

Query: 203 EANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCH 262
               +++K +P   + +ETD+P  G               P K+          RNEP +
Sbjct: 199 GQKQKLVKQLPLTSICLETDSPALG---------------PEKQV---------RNEPWN 234

Query: 263 IIQILEIMSAVRDEDPLELANTLYNNTIKVF 293
           I    E ++ V+     E+      N +K+F
Sbjct: 235 ISISAEYIAQVKGISVEEVIEVTTQNALKLF 265


>gi|110349734 TatD DNase domain containing 3 isoform 2 [Homo
           sapiens]
          Length = 273

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 64/271 (23%), Positives = 122/271 (45%), Gaps = 37/271 (13%)

Query: 31  DLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQT-NGMFFSTVGCHPTRCGEFEKNNP 89
           DL DV+ +A +  V   +    +  + +  + L++  NG     +G HP + G   ++  
Sbjct: 23  DLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQ-GLPPEDQR 81

Query: 90  DLYLKEL---LNLAENNKGKVVAIGECGLDFDRLQFC----PKDTQLKYFEKQFELSEQT 142
            + LK+L   L + EN K +++AIGE GLDF   +F      K+ Q +   +Q +L+++ 
Sbjct: 82  SVTLKDLDVALPIIENYKDRLLAIGEVGLDFSP-RFAGTGEQKEEQRQVLIRQIQLAKRL 140

Query: 143 KLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKT 202
            LP+ +H R++    +++++      V  ++H+FDG    A   +    +      S+  
Sbjct: 141 NLPVNVHSRSAGRPTINLLQEQGAEKV--LLHAFDGRPSVAMEGVRAGYFFSIPP-SIIR 197

Query: 203 EANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCH 262
               +++K +P   + +ETD+P  G               P K+          RNEP +
Sbjct: 198 SGQQKLVKQLPLTSICLETDSPALG---------------PEKQV---------RNEPWN 233

Query: 263 IIQILEIMSAVRDEDPLELANTLYNNTIKVF 293
           I    E ++ V+     E+      N +K+F
Sbjct: 234 ISISAEYIAQVKGISVEEVIEVTTQNALKLF 264


>gi|226061853 TatD DNase domain containing 3 isoform 5 [Homo
           sapiens]
          Length = 281

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 64/278 (23%), Positives = 124/278 (44%), Gaps = 43/278 (15%)

Query: 31  DLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQT-NGMFFSTVGCHPTRCGEFEKNNP 89
           DL DV+ +A +  V   +    +  + +  + L++  NG     +G HP + G   ++  
Sbjct: 23  DLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQ-GLPPEDQR 81

Query: 90  DLYLKEL---LNLAENNKGKVVAIGECGLDFDRLQFC----PKDTQLKYFEKQFELSEQT 142
            + LK+L   L + EN K +++AIGE GLDF   +F      K+ Q +   +Q +L+++ 
Sbjct: 82  SVTLKDLDVALPIIENYKDRLLAIGEVGLDFSP-RFAGTGEQKEEQRQVLIRQIQLAKRL 140

Query: 143 KLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKT 202
            LP+ +H R++    +++++      V  ++H+FDG    A   +    +       +++
Sbjct: 141 NLPVNVHSRSAGRPTINLLQEQGAEKV--LLHAFDGRPSVAMEGVRAGYFFSIPPSIIRS 198

Query: 203 EANL-------EVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLK 255
              L       +++K +P   + +ETD+P  G               P K+         
Sbjct: 199 GQLLSLFSKKQKLVKQLPLTSICLETDSPALG---------------PEKQV-------- 235

Query: 256 DRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVF 293
            RNEP +I    E ++ V+     E+      N +K+F
Sbjct: 236 -RNEPWNISISAEYIAQVKGISVEEVIEVTTQNALKLF 272


>gi|226061595 TatD DNase domain containing 3 isoform 3 [Homo
           sapiens]
          Length = 240

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 51/212 (24%), Positives = 103/212 (48%), Gaps = 19/212 (8%)

Query: 31  DLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQT-NGMFFSTVGCHPTRCGEFEKNNP 89
           DL DV+ +A +  V   +    +  + +  + L++  NG     +G HP + G   ++  
Sbjct: 23  DLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQ-GLPPEDQR 81

Query: 90  DLYLKEL---LNLAENNKGKVVAIGECGLDFDRLQFC----PKDTQLKYFEKQFELSEQT 142
            + LK+L   L + EN K +++AIGE GLDF   +F      K+ Q +   +Q +L+++ 
Sbjct: 82  SVTLKDLDVALPIIENYKDRLLAIGEVGLDFSP-RFAGTGEQKEEQRQVLIRQIQLAKRL 140

Query: 143 KLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKT 202
            LP+ +H R++    +++++      V  ++H+FDG    A   +    +       +++
Sbjct: 141 NLPVNVHSRSAGRPTINLLQEQGAEKV--LLHAFDGRPSVAMEGVRAGYFFSIPPSIIRS 198

Query: 203 EANL-------EVLKSIPSEKLMIETDAPWCG 227
              L       +++K +P   + +ETD+P  G
Sbjct: 199 GQLLSLFSKKQKLVKQLPLTSICLETDSPALG 230


>gi|226061614 TatD DNase domain containing 3 isoform 4 [Homo
           sapiens]
          Length = 253

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 53/264 (20%), Positives = 109/264 (41%), Gaps = 43/264 (16%)

Query: 31  DLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQT-NGMFFSTVGCHPTRCGEFEKNNP 89
           DL DV+ +A +  V   +    +  + +  + L++  NG     +G HP + G   ++  
Sbjct: 23  DLDDVLEKAKKANVVALVAVAEHSGEFEKIMQLSERYNGFVLPCLGVHPVQ-GLPPEDQR 81

Query: 90  DLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLH 149
            + LK  L+ +    G     GE            K+ Q +   +Q +L+++  LP+ +H
Sbjct: 82  SVTLKVGLDFSPRFAGT----GE-----------QKEEQRQVLIRQIQLAKRLNLPVNVH 126

Query: 150 CRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVL 209
            R++    +++++      V  ++H+FDG    A   +    +       +++    +++
Sbjct: 127 SRSAGRPTINLLQEQGAEKV--LLHAFDGRPSVAMEGVRAGYFFSIPPSIIRSGQKQKLV 184

Query: 210 KSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEI 269
           K +P   + +ETD+P  G               P K+          RNEP +I    E 
Sbjct: 185 KQLPLTSICLETDSPALG---------------PEKQV---------RNEPWNISISAEY 220

Query: 270 MSAVRDEDPLELANTLYNNTIKVF 293
           ++ V+     E+      N +K+F
Sbjct: 221 IAQVKGISVEEVIEVTTQNALKLF 244


>gi|157671947 hypothetical protein LOC79974 isoform 2 [Homo sapiens]
          Length = 783

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 189 LDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKW 248
           L+++  F   + KT+ +     S   +K + +   P+  +++  A    I      K + 
Sbjct: 506 LNVFEQFQFMNKKTQPHPLEWNSFTEDKNIEKPQVPFDAIENKKAAVPQI------KNEN 559

Query: 249 ESGHCLKDRNEPCHIIQI 266
           +  HC  D N PCHI QI
Sbjct: 560 KEIHCSDDENTPCHIKQI 577


>gi|157671945 hypothetical protein LOC79974 isoform 1 [Homo sapiens]
          Length = 1026

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 189 LDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKW 248
           L+++  F   + KT+ +     S   +K + +   P+  +++  A    I      K + 
Sbjct: 506 LNVFEQFQFMNKKTQPHPLEWNSFTEDKNIEKPQVPFDAIENKKAAVPQI------KNEN 559

Query: 249 ESGHCLKDRNEPCHIIQI 266
           +  HC  D N PCHI QI
Sbjct: 560 KEIHCSDDENTPCHIKQI 577


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 12/114 (10%)

Query: 133 EKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLY 192
           E+  ++++ T + + +HC       L   +   D    G+ H  +G    A A   L++ 
Sbjct: 307 EECVQITDSTLIQLSIHCPRLQVLSLSHCELITD---DGIRHLGNG----ACAHDQLEV- 358

Query: 193 IGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKK 246
           I  + C L T+A+LE LKS  S + +   D      + T AG K +RT  P  K
Sbjct: 359 IELDNCPLITDASLEHLKSCHSLERIELYDCQ----QITRAGIKRLRTHLPNIK 408


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 99  LAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFL 158
           L E +   V  + E   DF++++  P + +L+Y E+Q +   Q  LP  L  +    E L
Sbjct: 874 LLEKHDESVTDVTEVPQDFEKIK--PVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEIL 931

Query: 159 D 159
           D
Sbjct: 932 D 932


>gi|145309330 zinc finger protein 792 [Homo sapiens]
          Length = 632

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 4/74 (5%)

Query: 81  CGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSE 140
           CG+F  +   L   ++++  E   G     GECG  F R     K  ++   E+ +E +E
Sbjct: 427 CGKFFSHIASLIQHQIVHTGERPHG----CGECGKAFSRSSDLMKHQRVHTGERPYECNE 482

Query: 141 QTKLPMFLHCRNSH 154
             KL       NSH
Sbjct: 483 CGKLFSQSSSLNSH 496


>gi|4507157 sortilin-related receptor containing LDLR class A repeats
            preproprotein [Homo sapiens]
          Length = 2214

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 16/61 (26%)

Query: 149  HCRNSHAEFLDIMKRNRDRCV------GGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKT 202
            HC      F+D + +NR +C+       G++   DG+ E AA          F GCS   
Sbjct: 1270 HCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAA----------FAGCSQDP 1319

Query: 203  E 203
            E
Sbjct: 1320 E 1320


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,832,002
Number of Sequences: 37866
Number of extensions: 458526
Number of successful extensions: 965
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 945
Number of HSP's gapped (non-prelim): 15
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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