Guide to the Human Genome
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Search of human proteins with 7662482

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662482 dolichol kinase [Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662482 dolichol kinase [Homo sapiens]                            1056   0.0  
gi|31542327 solute carrier family 22, member 16 [Homo sapiens]         39   0.016
gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]             33   0.86 
gi|11225266 transient receptor potential cation channel, subfami...    32   1.1  
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...    32   1.9  
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...    32   1.9  
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...    32   1.9  
gi|196123584 ATP synthase F0 subunit 6 [Homo sapiens neanderthal...    31   3.3  
gi|251831112 ATP synthase F0 subunit 6 [Homo sapiens]                  30   4.3  
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       30   4.3  
gi|253735700 5-hydroxytryptamine (serotonin) receptor 3A isoform...    30   7.3  
gi|253735691 5-hydroxytryptamine (serotonin) receptor 3A isoform...    30   7.3  
gi|46240862 GPI deacylase [Homo sapiens]                               30   7.3  
gi|253735697 5-hydroxytryptamine (serotonin) receptor 3A isoform...    29   9.5  
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...    29   9.5  

>gi|7662482 dolichol kinase [Homo sapiens]
          Length = 538

 Score = 1056 bits (2732), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MTRECPSPAPGPGAPLSGSVLAEAAVVFAVVLSIHATVWDRYSWCAVALAVQAFYVQYKW 60
           MTRECPSPAPGPGAPLSGSVLAEAAVVFAVVLSIHATVWDRYSWCAVALAVQAFYVQYKW
Sbjct: 1   MTRECPSPAPGPGAPLSGSVLAEAAVVFAVVLSIHATVWDRYSWCAVALAVQAFYVQYKW 60

Query: 61  DRLLQQGSAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPFFERFGIVVAATGMA 120
           DRLLQQGSAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPFFERFGIVVAATGMA
Sbjct: 61  DRLLQQGSAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPFFERFGIVVAATGMA 120

Query: 121 VALFSSVLALGITRPVPTNTCVILGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMI 180
           VALFSSVLALGITRPVPTNTCVILGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMI
Sbjct: 121 VALFSSVLALGITRPVPTNTCVILGLAGGVIIYIMKHSLSVGEVIEVLEVLLIFVYLNMI 180

Query: 181 LLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGIF 240
           LLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGIF
Sbjct: 181 LLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGIF 240

Query: 241 FSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL 300
           FSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL
Sbjct: 241 FSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL 300

Query: 301 LAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLY 360
           LAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLY
Sbjct: 301 LAYWSLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLY 360

Query: 361 VAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIW 420
           VAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIW
Sbjct: 361 VAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIW 420

Query: 421 LIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSI 480
           LIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSI
Sbjct: 421 LIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSI 480

Query: 481 FAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA 538
           FAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA
Sbjct: 481 FAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA 538


>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
          Length = 577

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 225 FFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPL 284
           FFL +V  G +++G  +   F+ M S TWA S+  H    V +L V L     L+R    
Sbjct: 213 FFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHSFFAVGTLLVALTGY--LVR---T 266

Query: 285 LWLLQFLFQTDTRIYLLAYWSLLAT 309
            WL Q +  T T  ++L  W L  T
Sbjct: 267 WWLYQMILSTVTVPFILCCWVLPET 291


>gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]
          Length = 355

 Score = 32.7 bits (73), Expect = 0.86
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 7/88 (7%)

Query: 228 LVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLSLGVVLPWLHRLIRRNPLLWL 287
           L+   G +L+ +F+  LFVF   G   S +   L+ C     +   +L  L   + LL++
Sbjct: 29  LIQTNGKLLLAVFYCLLFVFSLLGN--SLVILVLVVCKKLRSITDVYLLNL-ALSDLLFV 85

Query: 288 LQFLFQTDTRIYLLAYWSLLATLACLVV 315
             F FQT    YLL  W +  T+ C VV
Sbjct: 86  FSFPFQT---YYLLDQW-VFGTVMCKVV 109


>gi|11225266 transient receptor potential cation channel, subfamily
           M, member 5 [Homo sapiens]
          Length = 1165

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 8/94 (8%)

Query: 154 IMKHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVL-------- 205
           + K +L VG+     +++ IF+++  +   +LP  F  G  +L +  + F L        
Sbjct: 796 VKKFTLYVGDNWNKCDMVAIFLFIVGVTCRMLPSAFEAGRTVLAMDFMVFTLRLIHIFAI 855

Query: 206 NQLIKRSLTLVESQGDPVDFFLLVVVVGMVLMGI 239
           ++ +   + +VE     V FFL  + V +V  G+
Sbjct: 856 HKQLGPKIIVVERMMKDVFFFLFFLSVWLVAYGV 889


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 439 VPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISV---ALILIFDS 495
           +P  G L  G+GD + +IFG ++  +     KK    T   + + I+ +    ++ +   
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256

Query: 496 GVDLNYSYAW 505
            V   Y   W
Sbjct: 257 AVIFKYIEGW 266


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 439 VPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISV---ALILIFDS 495
           +P  G L  G+GD + +IFG ++  +     KK    T   + + I+ +    ++ +   
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256

Query: 496 GVDLNYSYAW 505
            V   Y   W
Sbjct: 257 AVIFKYIEGW 266


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 439 VPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISV---ALILIFDS 495
           +P  G L  G+GD + +IFG ++  +     KK    T   + + I+ +    ++ +   
Sbjct: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251

Query: 496 GVDLNYSYAW 505
            V   Y   W
Sbjct: 252 AVIFKYIEGW 261


>gi|196123584 ATP synthase F0 subunit 6 [Homo sapiens
           neanderthalensis]
          Length = 226

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 28/110 (25%), Positives = 42/110 (38%), Gaps = 9/110 (8%)

Query: 162 GEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEAL---------LVLGGISFVLNQLIKRS 212
           G    ++ V LI       LL LLP  FTP   L         L  G +       IK +
Sbjct: 65  GRTWSLMLVSLIIFITTTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGAVIMGFRSKIKNA 124

Query: 213 LTLVESQGDPVDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLM 262
           L     QG P     ++V++  + + I    L V + +   A  +  HL+
Sbjct: 125 LAHFLPQGTPTPLIPMLVIIETISLLIQPVALAVRLTANITAGHLLMHLI 174


>gi|251831112 ATP synthase F0 subunit 6 [Homo sapiens]
          Length = 226

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 28/110 (25%), Positives = 42/110 (38%), Gaps = 9/110 (8%)

Query: 162 GEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEAL---------LVLGGISFVLNQLIKRS 212
           G    ++ V LI       LL LLP  FTP   L         L  G +       IK +
Sbjct: 65  GRTWSLMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTVIMGFRSKIKNA 124

Query: 213 LTLVESQGDPVDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLM 262
           L     QG P     ++V++  + + I    L V + +   A  +  HL+
Sbjct: 125 LAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLI 174


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 386  HTLRSFLSLFLDERDSGPLILTHIYLLLGMSL 417
            H  + +LSLFL    +G  ++TH Y L+G+ L
Sbjct: 3647 HEAKHYLSLFLSCYQTGASLVTHFYPLMGVEL 3678


>gi|253735700 5-hydroxytryptamine (serotonin) receptor 3A isoform b
           precursor [Homo sapiens]
          Length = 484

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 42/198 (21%)

Query: 259 FHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL-LAYWSLLATLACLVVLY 317
           F +  C L+      WLH +   N  LW L    ++D  +++    W LL  L       
Sbjct: 172 FDVQNCSLTF---TSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYF---- 224

Query: 318 QNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVR 377
              +  S ES  + A            +  Y+  +I  RPL YV + +  ++F+ +  + 
Sbjct: 225 ---REFSMESSNYYAE-----------MKFYV--VIRRRPLFYVVSLLLPSIFLMVMDIV 268

Query: 378 YFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIWLI--PRPCTQKGSLGGA 435
            F + P                +SG  +   I LLLG S+ + ++    P T  G+    
Sbjct: 269 GFYLPP----------------NSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIG 312

Query: 436 RALVPYAGVLAVGVGDTV 453
              V    +L + + +T+
Sbjct: 313 VYFVVCMALLVISLAETI 330


>gi|253735691 5-hydroxytryptamine (serotonin) receptor 3A isoform c
           [Homo sapiens]
          Length = 463

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 42/198 (21%)

Query: 259 FHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL-LAYWSLLATLACLVVLY 317
           F +  C L+      WLH +   N  LW L    ++D  +++    W LL  L       
Sbjct: 151 FDVQNCSLTF---TSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYF---- 203

Query: 318 QNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVR 377
              +  S ES  + A            +  Y+  +I  RPL YV + +  ++F+ +  + 
Sbjct: 204 ---REFSMESSNYYAE-----------MKFYV--VIRRRPLFYVVSLLLPSIFLMVMDIV 247

Query: 378 YFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSLPIWLI--PRPCTQKGSLGGA 435
            F + P                +SG  +   I LLLG S+ + ++    P T  G+    
Sbjct: 248 GFYLPP----------------NSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIG 291

Query: 436 RALVPYAGVLAVGVGDTV 453
              V    +L + + +T+
Sbjct: 292 VYFVVCMALLVISLAETI 309


>gi|46240862 GPI deacylase [Homo sapiens]
          Length = 922

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 23/113 (20%)

Query: 283 PLLWLLQFLFQTDTRIYLLAYWSLL---ATLACLVVLYQNAKRSSSESKKHQAPTIARKY 339
           PL+ L+ FLF T T     AYWS L   A++  L  L+   KR S   K           
Sbjct: 680 PLISLILFLFGTCT-----AYWSGLLSSASVRLLSSLWLALKRPSELPKD---------- 724

Query: 340 FHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRY-FRIKPLGHTLRSF 391
             + +++  +P +     L+ V+ T C A+ I L Y+ Y F++  L  +L +F
Sbjct: 725 --IKMISPDLPFLTI--VLIIVSWTTCGALAILLSYLYYVFKVVHLQASLTTF 773


>gi|253735697 5-hydroxytryptamine (serotonin) receptor 3A isoform a
           precursor [Homo sapiens]
          Length = 516

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 37/160 (23%), Positives = 61/160 (38%), Gaps = 40/160 (25%)

Query: 259 FHLMTCVLSLGVVLPWLHRLIRRNPLLWLLQFLFQTDTRIYL-LAYWSLLATLACLVVLY 317
           F +  C L+      WLH +   N  LW L    ++D  +++    W LL  L       
Sbjct: 172 FDVQNCSLTF---TSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYF---- 224

Query: 318 QNAKRSSSESKKHQAPTIARKYFHLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVR 377
              +  S ES  + A            +  Y+  +I  RPL YV + +  ++F+ +  + 
Sbjct: 225 ---REFSMESSNYYAE-----------MKFYV--VIRRRPLFYVVSLLLPSIFLMVMDIV 268

Query: 378 YFRIKPLGHTLRSFLSLFLDERDSGPLILTHIYLLLGMSL 417
            F + P                +SG  +   I LLLG S+
Sbjct: 269 GFYLPP----------------NSGERVSFKITLLLGYSV 292


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 357 PLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDER---DSGPLILTHIYL-L 412
           P L +AA V L   I L  ++  R++P         +L  D      +G +   ++ + +
Sbjct: 251 PFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFANMGIAM 310

Query: 413 LGMSLPIWLIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRW 466
           L  +LPIW++   C++K  LG   A +P +  ++  +G  +  I    MG  RW
Sbjct: 311 LEPALPIWMMETMCSRKWQLG--VAFLPAS--ISYLIGTNIFGILAHKMG--RW 358


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.143    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,656,471
Number of Sequences: 37866
Number of extensions: 774187
Number of successful extensions: 2835
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2822
Number of HSP's gapped (non-prelim): 18
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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