Search of human proteins with 7661728

Search of human proteins with 7661728

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661728 roadblock domain-containing protein 3 isoform 1
[Homo sapiens]
         (125 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661728 roadblock domain-containing protein 3 isoform 1 [Homo...   245   5e-66
gi|223671906 roadblock domain-containing protein 3 isoform 2 [Ho...   172   6e-44
gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo...    33   0.056
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    33   0.056
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            28   1.4  
gi|54792073 mucolipin 2 [Homo sapiens]                                 27   3.1  
gi|224922839 hypothetical protein LOC138311 [Homo sapiens]             26   6.8  
gi|16753215 profilin 2 isoform a [Homo sapiens]                        26   6.8  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...    26   8.9  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...    26   8.9  
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]          26   8.9  
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]         26   8.9  
gi|89886470 hypothetical protein LOC84960 [Homo sapiens]               26   8.9  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...    26   8.9  

>gi|7661728 roadblock domain-containing protein 3 isoform 1 [Homo
           sapiens]
          Length = 125

 Score =  245 bits (626), Expect = 5e-66
 Identities = 125/125 (100%), Positives = 125/125 (100%)

Query: 1   MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG 60
           MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG
Sbjct: 1   MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG 60

Query: 61  NQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLT 120
           NQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLT
Sbjct: 61  NQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLT 120

Query: 121 QVAAS 125
           QVAAS
Sbjct: 121 QVAAS 125


>gi|223671906 roadblock domain-containing protein 3 isoform 2 [Homo
           sapiens]
          Length = 95

 Score =  172 bits (436), Expect = 6e-44
 Identities = 95/125 (76%), Positives = 95/125 (76%), Gaps = 30/125 (24%)

Query: 1   MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG 60
           MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG
Sbjct: 1   MLRPKALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNG 60

Query: 61  NQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEEPLT 120
           NQAFNEDNLKFILMDCM                              AQALVQYLEEPLT
Sbjct: 61  NQAFNEDNLKFILMDCM------------------------------AQALVQYLEEPLT 90

Query: 121 QVAAS 125
           QVAAS
Sbjct: 91  QVAAS 95


>gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo
           sapiens]
          Length = 815

 Score = 33.1 bits (74), Expect = 0.056
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 26  NNEGSLLAYSGYGDTDARVTAAIASNIWAAYD-------RNGNQAFNEDNLKFILMDCME 78
           NNEG L    G GDT+ R T  + S   + +         N + A  ED   F+  D  E
Sbjct: 114 NNEGQL----GLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSE 169

Query: 79  GRVAITRVANLLLCMYAKETVG 100
           G++ +  V+N  +C+  + T+G
Sbjct: 170 GQIGLKNVSN--VCVPQQVTIG 189


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 33.1 bits (74), Expect = 0.056
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 26  NNEGSLLAYSGYGDTDARVTAAIASNIWAAYD-------RNGNQAFNEDNLKFILMDCME 78
           NNEG L    G GDT+ R T  + S   + +         N + A  ED   F+  D  E
Sbjct: 114 NNEGQL----GLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSE 169

Query: 79  GRVAITRVANLLLCMYAKETVG 100
           G++ +  V+N  +C+  + T+G
Sbjct: 170 GQIGLKNVSN--VCVPQQVTIG 189


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 28.5 bits (62), Expect = 1.4
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 61  NQAFNEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGML 104
           N  FN DN KF+++  +     I    N L+ M+A     F +L
Sbjct: 599 NHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALL 642


>gi|54792073 mucolipin 2 [Homo sapiens]
          Length = 566

 Score = 27.3 bits (59), Expect = 3.1
 Identities = 17/72 (23%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 20  QSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEG 79
           Q+T++ +N+        Y D+DA++      NI+ +  +N       D   F+++ C+  
Sbjct: 247 QNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFD--AFVIVICLAS 304

Query: 80  RVAITRVANLLL 91
            +  TR   L L
Sbjct: 305 LILCTRSIVLAL 316


>gi|224922839 hypothetical protein LOC138311 [Homo sapiens]
          Length = 431

 Score = 26.2 bits (56), Expect = 6.8
 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 13/104 (12%)

Query: 5   KALTQVLSQANTGGVQSTLLLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAF 64
           + +T    +AN G + S   L  +  L+A     + D RV+ A A ++WA   RN     
Sbjct: 153 REMTLSFLKANLGDLPSLPALVGQVLLMADF---NKDNRVSLAEAKSVWALLQRN----- 204

Query: 65  NEDNLKFILMDCMEGRVAITRVANLLLCMYAKETVGFGMLKAKA 108
                +F+L+  ++ +   +R+      +Y  E V  G   A A
Sbjct: 205 -----EFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAA 243


>gi|16753215 profilin 2 isoform a [Homo sapiens]
          Length = 140

 Score = 26.2 bits (56), Expect = 6.8
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 81  VAITRVANLLLCMYAKETVGFGMLKAKAQALVQYLEE 117
           VA+ R   +L+ +  KE V  G L  KA ++ +YL +
Sbjct: 101 VAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRD 137


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 1 [Homo sapiens]
          Length = 1635

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 13/60 (21%)

Query: 24  LLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAI 83
           +LN +G+ ++Y             I  N+W AY         E+NL  +  D  EG +++
Sbjct: 869 ILNFQGNYISY-------------IDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSL 915


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 2 [Homo sapiens]
          Length = 1700

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 13/60 (21%)

Query: 24  LLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAI 83
           +LN +G+ ++Y             I  N+W AY         E+NL  +  D  EG +++
Sbjct: 869 ILNFQGNYISY-------------IDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSL 915


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 13/60 (21%)

Query: 24  LLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAI 83
           +LN +G+ ++Y             I  N+W AY         E+NL  +  D  EG +++
Sbjct: 869 ILNFQGNYISY-------------IDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSL 915


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 13/60 (21%)

Query: 24  LLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAI 83
           +LN +G+ ++Y             I  N+W AY         E+NL  +  D  EG +++
Sbjct: 869 ILNFQGNYISY-------------IDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSL 915


>gi|89886470 hypothetical protein LOC84960 [Homo sapiens]
          Length = 534

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 14/46 (30%), Positives = 22/46 (47%)

Query: 45  TAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAITRVANLL 90
           +A   S++W    R   Q   E+NL+  + DC E RV +  +   L
Sbjct: 308 SAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQL 353


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
           sapiens]
          Length = 1634

 Score = 25.8 bits (55), Expect = 8.9
 Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 13/60 (21%)

Query: 24  LLNNEGSLLAYSGYGDTDARVTAAIASNIWAAYDRNGNQAFNEDNLKFILMDCMEGRVAI 83
           +LN +G+ ++Y             I  N+W AY         E+NL  +  D  EG +++
Sbjct: 869 ILNFQGNYISY-------------IDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSL 915


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.130    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,807,705
Number of Sequences: 37866
Number of extensions: 124898
Number of successful extensions: 198
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 192
Number of HSP's gapped (non-prelim): 15
length of query: 125
length of database: 18,247,518
effective HSP length: 90
effective length of query: 35
effective length of database: 14,839,578
effective search space: 519385230
effective search space used: 519385230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.