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Search of human proteins with 7657347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657347 mitochondrial carrier 2 [Homo sapiens]
(303 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657347 mitochondrial carrier 2 [Homo sapiens] 618 e-177
gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens] 303 9e-83
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 50 2e-06
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 47 2e-05
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 44 2e-04
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 44 2e-04
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 44 2e-04
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 42 9e-04
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 41 0.001
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 41 0.001
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 41 0.001
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 40 0.002
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 39 0.006
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 39 0.006
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 39 0.007
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 38 0.010
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 38 0.010
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 38 0.013
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 37 0.028
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 36 0.037
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 34 0.14
gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 34 0.18
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 34 0.18
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 34 0.18
gi|11225256 uncoupling protein 1 [Homo sapiens] 33 0.24
gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo... 33 0.24
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 33 0.24
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 33 0.24
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 33 0.31
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 33 0.31
>gi|7657347 mitochondrial carrier 2 [Homo sapiens]
Length = 303
Score = 618 bits (1593), Expect = e-177
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQH 60
MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQH
Sbjct: 1 MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQH 60
Query: 61 IASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHV 120
IASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHV
Sbjct: 61 IASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHV 120
Query: 121 IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA 180
IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA
Sbjct: 121 IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA 180
Query: 181 GLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLV 240
GLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLV
Sbjct: 181 GLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLV 240
Query: 241 SNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLK 300
SNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLK
Sbjct: 241 SNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLK 300
Query: 301 MLI 303
MLI
Sbjct: 301 MLI 303
>gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens]
Length = 372
Score = 303 bits (777), Expect = 9e-83
Identities = 142/291 (48%), Positives = 202/291 (69%), Gaps = 4/291 (1%)
Query: 8 VLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGR 67
V LG+G+T LS PL+YVK+LIQVG+EP+PPT+G N+ GR+V LP F+YA++I +DG+
Sbjct: 86 VALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGK 145
Query: 68 RGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTRE 127
GLF GL+PRL S L TV G + + + +E+ + + ++ +S V+KET+ E
Sbjct: 146 IGLFRGLSPRLMSNALSTVTRGSMKKVFPP----DEIEQVSNKDDMKTSLKKVVKETSYE 201
Query: 128 MIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLL 187
M+ + + ++ HP HVI++R MVQF+GRE+KY G+ SI I++EEG+LGFF GL+P LL
Sbjct: 202 MMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLL 261
Query: 188 GDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVN 247
GD++ LW CN LA+ +N Y +D S ++SY++ V G SMLTYPF+LV +LMAVN
Sbjct: 262 GDVVFLWGCNLLAHFINAYLVDDSFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVN 321
Query: 248 NCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCD 298
NCGL G PPYSP++ SWI CW L +G + RG+SL FR+V G + +
Sbjct: 322 NCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE 372
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/205 (23%), Positives = 86/205 (41%), Gaps = 37/205 (18%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHG---KVLQHYQESDKGEELGPGNV 109
G+ I +DG RGL+ G+TP + L ++ ++ Y+ + E L
Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERL----- 118
Query: 110 QKEVSSSFDHVIKETTREMIARSAA----TLITHPFHVITLRSMVQFIG----RESKYCG 161
E T +++ + A IT+P V R M+Q+ +Y G
Sbjct: 119 -------------EATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKG 165
Query: 162 LCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSY 221
+ D+++ IY+ EG+ G + G VP L G S +AY + + ++ + E +
Sbjct: 166 MFDTLVKIYKYEGVRGLYKGFVPGLFG--TSHGALQFMAYELLKLKYNQHINRLPEAQLS 223
Query: 222 S------QAVTGFFASMLTYPFVLV 240
+ A++ FA TYP+ +V
Sbjct: 224 TVEYISVAALSKIFAVAATYPYQVV 248
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/177 (26%), Positives = 72/177 (40%), Gaps = 20/177 (11%)
Query: 11 GSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGRRGL 70
G+ ++ PL K + + Y+ + + R Q G+F I +G RGL
Sbjct: 131 GAMTLCITNPLWVTKTRLMLQYDAVVNSPHR--------QYKGMFDTLVKIYKYEGVRGL 182
Query: 71 FTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIA 130
+ G P G+ GT HG + E K + N E S I I
Sbjct: 183 YKGFVP----GLFGTS-HGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIF 237
Query: 131 RSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLL 187
AAT +P+ V+ R Q + Y G+ D I +R+EG+ GF+ G+ P L+
Sbjct: 238 AVAAT---YPYQVVRARLQDQHMF----YSGVIDVITKTWRKEGVGGFYKGIAPNLI 287
Score = 33.5 bits (75), Expect = 0.24
Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
Query: 114 SSSFDHVIKETTREMIARSA-ATLITHPFHVITLRSMVQF-IGRESKYCGLCDSIITIYR 171
S+ F HV E ++ + L HP ++ +R V + KY G+ + TI++
Sbjct: 15 STVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWK 74
Query: 172 EEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSY--SQAVTGFF 229
+G+ G + G+ P + G LS L + +Y + G + E Y S A G
Sbjct: 75 LDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTE-GRAERLEATEYLVSAAEAGAM 133
Query: 230 ASMLTYP 236
+T P
Sbjct: 134 TLCITNP 140
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 47.0 bits (110), Expect = 2e-05
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 37/187 (19%)
Query: 10 LGSGLT--ILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDG- 66
LGSGLT I+ P VKV +Q RN F Q P YA+ I +G
Sbjct: 117 LGSGLTEAIVVNPFEVVKVGLQAN---------RNTFAEQ----PSTVGYARQIIKKEGW 163
Query: 67 -RRGLFTGLTPRLCS-GVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKET 124
+GL GLT L GV V G NV+ + + D +++
Sbjct: 164 GLQGLNKGLTATLGRHGVFNMVYFGFYY---------------NVKNMIPVNKDPILEFW 208
Query: 125 TR---EMIARSAATLITHPFHVITLRSM-VQFIGRESKYCGLCDSIITIYREEGILGFFA 180
+ +++ + A++I PF V R Q + E KY ++ T+Y+EEGIL +
Sbjct: 209 RKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYK 268
Query: 181 GLVPRLL 187
GL+P+++
Sbjct: 269 GLLPKIM 275
Score = 44.3 bits (103), Expect = 1e-04
Identities = 22/75 (29%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 120 VIKETTREMIARSAATLIT----HPFHVITLRSMVQFIGRE-SKYCGLCDSIITIYREEG 174
+++E +R+++A +A L+ HP V+ R +Q + + Y L DS I++ EG
Sbjct: 9 LVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEG 68
Query: 175 ILGFFAGLVPRLLGD 189
+ GF+ G++P +L +
Sbjct: 69 LFGFYKGILPPILAE 83
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/153 (28%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A ATL HP V+ R Q G Y L ++ T+YR EG F+ GL P L+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 189 DI----LSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLM 244
L +SL +L G N + G + LTYP L +
Sbjct: 185 IFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRL 244
Query: 245 AVNNCGLAGGCPPYSPIYTSWIDC-WCMLQKEG 276
V A Y +DC +LQKEG
Sbjct: 245 QVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Score = 35.4 bits (80), Expect = 0.063
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 8 VLLGSGLTILSQPLMY----VKVLIQVG-YEPLPPTIGRNIFGRQVCQLPGLFSYAQHIA 62
+L GSG ++S+ L Y K +QVG +E R FG QV + GL A+ +
Sbjct: 220 LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH-----ARAAFG-QVRRYKGLMDCAKQVL 273
Query: 63 SIDGRRGLFTGLTPRLCSGVLGT 85
+G G F GL+P L L T
Sbjct: 274 QKEGALGFFKGLSPSLLKAALST 296
Score = 35.0 bits (79), Expect = 0.082
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 154 GRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILS 192
G+ +Y GL D + ++EG LGFF GL P LL LS
Sbjct: 257 GQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295
Score = 28.5 bits (62), Expect = 7.7
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 9/65 (13%)
Query: 129 IARSAATLITH----PFHVITLRSMVQF--IGRE---SKYCGLCDSIITIYREEGILGFF 179
+A S + L+T PF VI +R +Q + R +KY G+ + I +EEG F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 180 AGLVP 184
G VP
Sbjct: 80 KGHVP 84
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/153 (28%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A ATL HP V+ R Q G Y L ++ T+YR EG F+ GL P L+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 189 DI----LSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLM 244
L +SL +L G N + G + LTYP L +
Sbjct: 185 IFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRL 244
Query: 245 AVNNCGLAGGCPPYSPIYTSWIDC-WCMLQKEG 276
V A Y +DC +LQKEG
Sbjct: 245 QVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Score = 35.4 bits (80), Expect = 0.063
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 8 VLLGSGLTILSQPLMY----VKVLIQVG-YEPLPPTIGRNIFGRQVCQLPGLFSYAQHIA 62
+L GSG ++S+ L Y K +QVG +E R FG QV + GL A+ +
Sbjct: 220 LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH-----ARAAFG-QVRRYKGLMDCAKQVL 273
Query: 63 SIDGRRGLFTGLTPRLCSGVLGT 85
+G G F GL+P L L T
Sbjct: 274 QKEGALGFFKGLSPSLLKAALST 296
Score = 35.0 bits (79), Expect = 0.082
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 154 GRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILS 192
G+ +Y GL D + ++EG LGFF GL P LL LS
Sbjct: 257 GQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295
Score = 28.5 bits (62), Expect = 7.7
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 9/65 (13%)
Query: 129 IARSAATLITH----PFHVITLRSMVQF--IGRE---SKYCGLCDSIITIYREEGILGFF 179
+A S + L+T PF VI +R +Q + R +KY G+ + I +EEG F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 180 AGLVP 184
G VP
Sbjct: 80 KGHVP 84
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/153 (28%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A ATL HP V+ R Q G Y L ++ T+YR EG F+ GL P L+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 189 DI----LSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLM 244
L +SL +L G N + G + LTYP L +
Sbjct: 185 IFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRL 244
Query: 245 AVNNCGLAGGCPPYSPIYTSWIDC-WCMLQKEG 276
V A Y +DC +LQKEG
Sbjct: 245 QVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Score = 35.4 bits (80), Expect = 0.063
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 8 VLLGSGLTILSQPLMY----VKVLIQVG-YEPLPPTIGRNIFGRQVCQLPGLFSYAQHIA 62
+L GSG ++S+ L Y K +QVG +E R FG QV + GL A+ +
Sbjct: 220 LLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH-----ARAAFG-QVRRYKGLMDCAKQVL 273
Query: 63 SIDGRRGLFTGLTPRLCSGVLGT 85
+G G F GL+P L L T
Sbjct: 274 QKEGALGFFKGLSPSLLKAALST 296
Score = 35.0 bits (79), Expect = 0.082
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 154 GRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILS 192
G+ +Y GL D + ++EG LGFF GL P LL LS
Sbjct: 257 GQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295
Score = 28.5 bits (62), Expect = 7.7
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 9/65 (13%)
Query: 129 IARSAATLITH----PFHVITLRSMVQF--IGRE---SKYCGLCDSIITIYREEGILGFF 179
+A S + L+T PF VI +R +Q + R +KY G+ + I +EEG F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 180 AGLVP 184
G VP
Sbjct: 80 KGHVP 84
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 41.6 bits (96), Expect = 9e-04
Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 15/152 (9%)
Query: 58 AQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPG-NVQKEVSSS 116
A+++ +G RG + GLT +G+ T++ + + ++ K L N ++ S+S
Sbjct: 174 ARYVYQTEGIRGFYRGLTASY-AGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTS 232
Query: 117 FDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGIL 176
F ++ +++ A+ I +P VI R + +KY + ++REEG L
Sbjct: 233 FFGLMAAAA---LSKGCASCIAYPHEVIRTRLREE----GTKYKSFVQTARLVFREEGYL 285
Query: 177 GFFAGLVPRLLGDILSLWLCNSLAYLVNTYAL 208
F+ GL +L+ I + A +++TY L
Sbjct: 286 AFYRGLFAQLIRQI------PNTAIVLSTYEL 311
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/181 (22%), Positives = 70/181 (38%), Gaps = 14/181 (7%)
Query: 52 PGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQK 111
PGLF + I +G + LF GL P L V+ +E G + N+
Sbjct: 72 PGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIV- 130
Query: 112 EVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYR 171
H+ + I S + +P ++ R ++ R SK +Y+
Sbjct: 131 -------HIFSAGSAAFITNS----LMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQ 179
Query: 172 EEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGV-STMNEMKSYSQAVTGFFA 230
EGI GF+ GL G I +C ++ + Y ++ + S+ N + S + G A
Sbjct: 180 TEGIRGFYRGLTASYAG-ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMA 238
Query: 231 S 231
+
Sbjct: 239 A 239
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 14/162 (8%)
Query: 121 IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA 180
++E I+ + ++ HPF + +R Q + Y G+ D ++ IYR E +LGFF
Sbjct: 3 VEEFVAGWISGALGLVLGHPFDTVKVRLQTQ-----TTYRGIVDCMVKIYRHESLLGFFK 57
Query: 181 GL-----VPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVT-GFFASMLT 234
G+ ++ +L N+L L T + + M + T GF +
Sbjct: 58 GMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCL 117
Query: 235 YPFVLVS-NLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKE 275
PF L+ L G PP P Y + C + +E
Sbjct: 118 APFDLIKVRLQNQTEPRAQPGSPP--PRYQGPVHCAASIFRE 157
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/137 (24%), Positives = 60/137 (43%), Gaps = 14/137 (10%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKE 112
G+FS + + +G GL+ G + + +HY+ + G+V +
Sbjct: 75 GVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRL 134
Query: 113 VSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYRE 172
++ S +A A + T+P ++ +R Q G S Y G+ + TIY +
Sbjct: 135 MAGS------------MAGMTAVICTYPLDMVRVRLAFQVKGEHS-YTGIIHAFKTIYAK 181
Query: 173 EG-ILGFFAGLVPRLLG 188
EG GF+ GL+P +LG
Sbjct: 182 EGGFFGFYRGLMPTILG 198
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 13/143 (9%)
Query: 45 GRQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEEL 104
G + Q GL IA DG GL+ G V G +V+ ++ KG
Sbjct: 160 GPEERQFKGLGDCIMKIAKSDGIAGLYQGFGV----SVQGIIVYRASYFGAYDTVKGLLP 215
Query: 105 GPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCD 164
P VS V+ + + ++++PF + R M+Q + +Y G D
Sbjct: 216 KPKKTPFLVSFFIAQVVT---------TCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLD 266
Query: 165 SIITIYREEGILGFFAGLVPRLL 187
+ IY+ EGI FF G +L
Sbjct: 267 CFVKIYQHEGISSFFRGAFSNVL 289
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 109 VQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLR---SMVQFIGRESKYCGLCDS 165
VQK+ D + MI+ A ++ PF V++ R V GR Y GL D
Sbjct: 195 VQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDC 254
Query: 166 IITIYREEGILGFFAGLVPRLL 187
++ I+R+EG L + GL P L
Sbjct: 255 MVKIWRQEGPLALYKGLGPAYL 276
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A + A +P V+ R V G+ +Y G+ D I + EG+ F+ G VP LLG
Sbjct: 297 MAGATAQTFIYPMEVMKTRLAV---GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 353
Query: 189 DILSLWLCNSLAYLVNTYALDS 210
I + ++ L+ +Y LD+
Sbjct: 354 IIPYAGIDLAVYELLKSYWLDN 375
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A + A +P V+ R V G+ +Y G+ D I + EG+ F+ G VP LLG
Sbjct: 278 MAGATAQTFIYPMEVMKTRLAV---GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 334
Query: 189 DILSLWLCNSLAYLVNTYALDS 210
I + ++ L+ +Y LD+
Sbjct: 335 IIPYAGIDLAVYELLKSYWLDN 356
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 38.5 bits (88), Expect = 0.007
Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 9/122 (7%)
Query: 133 AATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILS 192
A L+ HPF + +R VQ + + +Y G +I ++E +LG + GL L+G
Sbjct: 14 AGVLVGHPFDTVKVRLQVQSV-EKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMG---- 68
Query: 193 LWLCNSLAYLV--NTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCG 250
L N+L + V NT S +N+ + A G ++ P L + + + G
Sbjct: 69 LTFINALVFGVQGNTLRALGHDSPLNQF--LAGAAAGAIQCVICCPMELAKTRLQLQDAG 126
Query: 251 LA 252
A
Sbjct: 127 PA 128
Score = 34.3 bits (77), Expect = 0.14
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 136 LITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWL 195
+I P + R +Q G Y G D + IY EG+ G G+V LL + S +
Sbjct: 108 VICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
Query: 196 CNSLAYLVNTYAL--DSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAG 253
L Y T AL + G + + +G + + TYP +V + + + GL G
Sbjct: 168 -YFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD--GLRG 224
Query: 254 GCPPYSPIYTSWIDC 268
+P Y +DC
Sbjct: 225 -----APRYRGILDC 234
Score = 28.5 bits (62), Expect = 7.7
Identities = 17/52 (32%), Positives = 23/52 (44%)
Query: 136 LITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLL 187
L T+P V+ R + +Y G+ D + YR EG F GL LL
Sbjct: 205 LSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLL 256
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 38.1 bits (87), Expect = 0.010
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 15/131 (11%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKE 112
GL I DG RGL+ G + V G +++ ++ KG P N
Sbjct: 156 GLGDCLVKITKSDGIRGLYQGFSV----SVQGIIIYRAAYFGVYDTAKGMLPDPKNT--- 208
Query: 113 VSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQF--IGRESKYCGLCDSIITIY 170
H++ + A ++++PF + R M+Q G + Y G D I+
Sbjct: 209 ------HIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIF 262
Query: 171 REEGILGFFAG 181
R+EG FF G
Sbjct: 263 RDEGGKAFFKG 273
Score = 33.5 bits (75), Expect = 0.24
Identities = 31/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)
Query: 154 GRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVS 213
G E ++ GL D ++ I + +GI G + G + G I+ + D +
Sbjct: 149 GTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNT 208
Query: 214 TMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQ 273
+ +Q VT A +++YPF V M + + G +YT +DCW +
Sbjct: 209 HIVVSWMIAQTVTAV-AGVVSYPFDTVRRRMMMQS-----GRKGADIMYTGTVDCWRKIF 262
Query: 274 KEGNMSRGNSLFFR 287
++ G FF+
Sbjct: 263 RD----EGGKAFFK 272
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 38.1 bits (87), Expect = 0.010
Identities = 53/255 (20%), Positives = 93/255 (36%), Gaps = 30/255 (11%)
Query: 9 LLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGRR 68
L G G T+ QPL VK +Q+ E G + + F I +G R
Sbjct: 30 LAGMGATVFVQPLDLVKNRMQLSGE-----------GAKTREYKTSFHALTSILKAEGLR 78
Query: 69 GLFTGLTPRLCSGVLGTVVH-GKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTRE 127
G++TGL+ L T G ++ + PG + K V
Sbjct: 79 GIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIG------------ 126
Query: 128 MIARSAATLITHPFHVITLRSMVQF---IGRESKYCGLCDSIITIYREEGILGFFAGLVP 184
M A + + P V +R + Y + +++I I REEG+L + G +P
Sbjct: 127 MTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIP 186
Query: 185 RLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSY-SQAVTGFFASMLTYPFVLVSNL 243
+ ++ + + LDSG + N + + + ++G + + P +
Sbjct: 187 TMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKT- 245
Query: 244 MAVNNCGLAGGCPPY 258
+ N + G P Y
Sbjct: 246 -RIQNMRMIDGKPEY 259
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 37.7 bits (86), Expect = 0.013
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 11/161 (6%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A +T++T+P +I R ++Q I E Y GL + TIY++EG L + G+ ++G
Sbjct: 115 LAGMVSTIVTYPTDLIKTRLIMQNI-LEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVG 173
Query: 189 DILSLWLCNSLAYLVNTYALDSGVSTMNEMKS--YSQAVTGFFASMLTYPFVLVSNLMAV 246
+ + SL +N + +G + + + L++PF V M
Sbjct: 174 AL--PFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQA 231
Query: 247 NNCGL--AGGCPPYSPIYTSWIDCWCMLQK-EGNMSRGNSL 284
+ L +GG + ++ +DC+ + K +G + N L
Sbjct: 232 QSPYLPHSGGVDVH---FSGAVDCFRQIVKAQGVLGLWNGL 269
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 36.6 bits (83), Expect = 0.028
Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 10/134 (7%)
Query: 154 GRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVS 213
G E ++ GL D ++ IY+ +GI G + G + G I+ + D +
Sbjct: 149 GAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNT 208
Query: 214 TMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQ 273
+ +Q VT A + +YPF V M + + G +YT +DCW +
Sbjct: 209 HIVISWMIAQTVTA-VAGLTSYPFDTVRRRMMMQS-----GRKGTDIMYTGTLDCWRKIA 262
Query: 274 KEGNMSRGNSLFFR 287
++ G FF+
Sbjct: 263 RD----EGGKAFFK 272
Score = 33.1 bits (74), Expect = 0.31
Identities = 33/131 (25%), Positives = 49/131 (37%), Gaps = 15/131 (11%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKE 112
GL I DG +GL+ G V G +++ ++ KG P N
Sbjct: 156 GLGDCLVKIYKSDGIKGLYQGFNV----SVQGIIIYRAAYFGIYDTAKGMLPDPKNT--- 208
Query: 113 VSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQF--IGRESKYCGLCDSIITIY 170
H++ + A L ++PF + R M+Q G + Y G D I
Sbjct: 209 ------HIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIA 262
Query: 171 REEGILGFFAG 181
R+EG FF G
Sbjct: 263 RDEGGKAFFKG 273
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 36.2 bits (82), Expect = 0.037
Identities = 36/122 (29%), Positives = 51/122 (41%), Gaps = 21/122 (17%)
Query: 65 DGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKET 124
DG RGL+ G V G +++ ++ KG P NV VS
Sbjct: 168 DGLRGLYQGFNV----SVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSW--------- 214
Query: 125 TREMIARSA---ATLITHPFHVITLRSMVQF--IGRESKYCGLCDSIITIYREEGILGFF 179
MIA+S A L+++PF + R M+Q G + Y G D I ++EG FF
Sbjct: 215 ---MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFF 271
Query: 180 AG 181
G
Sbjct: 272 KG 273
Score = 33.9 bits (76), Expect = 0.18
Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 22/138 (15%)
Query: 156 ESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGV--- 212
+ ++ GL D II I++ +G+ G + G + G I+ A Y G+
Sbjct: 151 QREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYR------AAYFGVYDTAKGMLPD 204
Query: 213 -STMNEMKSY--SQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCW 269
++ S+ +Q+VT A +++YPF V M + + G +YT +DCW
Sbjct: 205 PKNVHIFVSWMIAQSVTAV-AGLVSYPFDTVRRRMMMQS-----GRKGADIMYTGTVDCW 258
Query: 270 CMLQKEGNMSRGNSLFFR 287
+ K+ G FF+
Sbjct: 259 RKIAKD----EGAKAFFK 272
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 34.3 bits (77), Expect = 0.14
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 119 HVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGF 178
HV + +A + A I +P V+ R ++ R +Y GL D I EG F
Sbjct: 278 HVQERFVAGSLAGATAQTIIYPMEVLKTRLTLR---RTGQYKGLLDCARRILEREGPRAF 334
Query: 179 FAGLVPRLLGDI 190
+ G +P +LG I
Sbjct: 335 YRGYLPNVLGII 346
>gi|157388925 solute carrier family 25, member 38 [Homo sapiens]
Length = 304
Score = 33.9 bits (76), Expect = 0.18
Identities = 33/134 (24%), Positives = 66/134 (49%), Gaps = 14/134 (10%)
Query: 54 LFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEV 113
+++ + I +G RGLF+GLT L + G L Y ++ + + P + +V
Sbjct: 161 IYAALRSIYHSEGHRGLFSGLTATL---LRDAPFSGIYLMFYNQT---KNIVPHD---QV 211
Query: 114 SSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREE 173
++ + + + A A+L+T P VI ++ +Q + ++ G ++ I+++
Sbjct: 212 DATLIPITNFSCG-IFAGILASLVTQPADVI--KTHMQLYPLKFQWIG--QAVTLIFKDY 266
Query: 174 GILGFFAGLVPRLL 187
G+ GFF G +PR L
Sbjct: 267 GLRGFFQGGIPRAL 280
Score = 33.5 bits (75), Expect = 0.24
Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 12/120 (10%)
Query: 130 ARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGD 189
+RS A + P VI R G ES Y L +IY EG G F+GL LL D
Sbjct: 133 SRSVAGVCMSPITVIKTRYESGKYGYESIYAALR----SIYHSEGHRGLFSGLTATLLRD 188
Query: 190 I----LSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAV-TGFFASMLTYPFVLVSNLM 244
+ L N +V +D +T+ + ++S + G AS++T P ++ M
Sbjct: 189 APFSGIYLMFYNQTKNIVPHDQVD---ATLIPITNFSCGIFAGILASLVTQPADVIKTHM 245
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 33.9 bits (76), Expect = 0.18
Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 52 PGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQK 111
PG + I +G R LF GL P L ++ + +E + P + Q
Sbjct: 62 PGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEK-LNDVFDPDSTQV 120
Query: 112 EVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYR 171
+ S+ +A A T+P +I R + R + G + + +Y+
Sbjct: 121 HMISA-----------AMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQ 169
Query: 172 EEGILGFFAGL 182
+G+ GF+ G+
Sbjct: 170 TDGLKGFYRGM 180
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 33.9 bits (76), Expect = 0.18
Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 52 PGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQK 111
PG + I +G R LF GL P L ++ + +E + P + Q
Sbjct: 62 PGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEK-LNDVFDPDSTQV 120
Query: 112 EVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYR 171
+ S+ +A A T+P +I R + R + G + + +Y+
Sbjct: 121 HMISA-----------AMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQ 169
Query: 172 EEGILGFFAGL 182
+G+ GF+ G+
Sbjct: 170 TDGLKGFYRGM 180
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 33.5 bits (75), Expect = 0.24
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 14/135 (10%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKE 112
G ++ + IA+ +G GL+ G TP L V +++ L Y + + V+
Sbjct: 156 GTYNAYRIIATTEGLTGLWKGTTPNLMRSV---IINCTELVTY------DLMKEAFVKNN 206
Query: 113 VSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYRE 172
+ + D V +IA AT ++ P V+ R + G+ Y + + + ++
Sbjct: 207 ILA--DDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPPGQ---YKSVPNCAMKVFTN 261
Query: 173 EGILGFFAGLVPRLL 187
EG FF GLVP L
Sbjct: 262 EGPTAFFKGLVPSFL 276
Score = 31.2 bits (69), Expect = 1.2
Identities = 51/235 (21%), Positives = 86/235 (36%), Gaps = 37/235 (15%)
Query: 16 ILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGRRGLFTGLT 75
+++ PL KV +QV E PT V + G+ + +GR L++GL
Sbjct: 29 VITFPLDTAKVRLQVQGEC--PT-------SSVIRYKGVLGTITAVVKTEGRMKLYSGLP 79
Query: 76 PRLCSGVLGTVVHGKVLQHYQES-DKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAA 134
L + + + QE G+E P K ++ + A
Sbjct: 80 AGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAG------------LTTGGVA 127
Query: 135 TLITHPFHVITLRSMVQ--FIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILS 192
I P V+ +R Q G + +Y G ++ I EG+ G + G P L+ ++
Sbjct: 128 VFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVII 187
Query: 193 LWLCNSLAYLVNTYALDSGVSTMNEMKS-------YSQAVTGFFASMLTYPFVLV 240
C L TY L N + + S + GF A+ ++ P +V
Sbjct: 188 --NCTELV----TYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVV 236
>gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo
sapiens]
Length = 205
Score = 33.5 bits (75), Expect = 0.24
Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 24/139 (17%)
Query: 53 GLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKE 112
G F I DG RG + G L + + + V Y E +
Sbjct: 56 GTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQ----------LSYL 105
Query: 113 VSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYR- 171
H++ + +A + A+++T+P VI R+ VQ G+ +SII +R
Sbjct: 106 CPKECPHIVFQAVSGPLAAATASILTNPMDVI--RTRVQVEGK--------NSIILTFRQ 155
Query: 172 ---EEGILGFFAGLVPRLL 187
EEG G GL R++
Sbjct: 156 LMAEEGPWGLMKGLSARII 174
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 33.5 bits (75), Expect = 0.24
Identities = 21/63 (33%), Positives = 29/63 (46%)
Query: 128 MIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLL 187
M++ T I P I +Q ESKY G D +Y+E GI G + G V L+
Sbjct: 118 MLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLM 177
Query: 188 GDI 190
D+
Sbjct: 178 RDV 180
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 33.5 bits (75), Expect = 0.24
Identities = 52/256 (20%), Positives = 92/256 (35%), Gaps = 56/256 (21%)
Query: 15 TILSQPLMYVKVLIQVGYEPLPPTI------------------GRNIFGRQVCQLPGLFS 56
+++ PL VK+ +Q PLP G ++ ++ G
Sbjct: 30 SVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGTLD 89
Query: 57 YAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSS 116
I +G + L++GL P L V TV++ + + LG + +
Sbjct: 90 AFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK-LGENETCIPIVAG 148
Query: 117 FDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGIL 176
++AR A + P +I R+ +Q ++ Y L + E+G +
Sbjct: 149 -----------IVARFGAVTVISPLELI--RTKMQ--SKKFSYVELHRFVSKKVSEDGWI 193
Query: 177 GFFAGLVPRLLGD------------ILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQA 224
+ G P +L D IL WLC T+ ++ S A
Sbjct: 194 SLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFT----------SGA 243
Query: 225 VTGFFASMLTYPFVLV 240
++G FA++ T PF +V
Sbjct: 244 LSGSFAAVATLPFDVV 259
Score = 29.6 bits (65), Expect = 3.4
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 125 TREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIIT------IYREEGILGF 178
T ++ S A + T PF V+ + Q ES + + T I + G G
Sbjct: 240 TSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGL 299
Query: 179 FAGLVPRLLGDILSLWLCNSLAYLVNTY 206
F+GL+PRL+ + + A +++TY
Sbjct: 300 FSGLIPRLIK------IAPACAIMISTY 321
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 33.1 bits (74), Expect = 0.31
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A + A +P V+ R ++ G+ Y G+ D I EG+ F+ G VP +LG
Sbjct: 289 LAGAIAQSSIYPMEVLKTRMALRKTGQ---YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
Query: 189 DI 190
I
Sbjct: 346 II 347
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 33.1 bits (74), Expect = 0.31
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 129 IARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLG 188
+A + A +P V+ R ++ G+ Y G+ D I EG+ F+ G VP +LG
Sbjct: 323 LAGAIAQSSIYPMEVLKTRMALRKTGQ---YSGMLDCARRILAREGVAAFYKGYVPNMLG 379
Query: 189 DI 190
I
Sbjct: 380 II 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,401,222
Number of Sequences: 37866
Number of extensions: 488737
Number of successful extensions: 1388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1279
Number of HSP's gapped (non-prelim): 112
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.