Guide to the Human Genome
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Search of human proteins with 74271837

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74271837 glutamine synthetase [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74271826 glutamine synthetase [Homo sapiens]                       793   0.0  
gi|74271837 glutamine synthetase [Homo sapiens]                       793   0.0  
gi|19923206 glutamine synthetase [Homo sapiens]                       793   0.0  
gi|221307485 lengsin, lens protein with glutamine synthetase dom...    34   0.19 
gi|58330892 interferon-induced protein with tetratricopeptide re...    32   0.71 
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    30   4.6  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    30   4.6  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    30   4.6  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    30   4.6  
gi|116534937 interferon-induced protein with tetratricopeptide r...    29   7.8  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    29   7.8  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    29   7.8  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    29   7.8  

>gi|74271826 glutamine synthetase [Homo sapiens]
          Length = 373

 Score =  793 bits (2048), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60
           MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW
Sbjct: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60

Query: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120
           NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI
Sbjct: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120

Query: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180
           MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY
Sbjct: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180

Query: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240
           RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP
Sbjct: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240

Query: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300
           KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
Sbjct: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300

Query: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360
           TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL
Sbjct: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360

Query: 361 LNETGDEPFQYKN 373
           LNETGDEPFQYKN
Sbjct: 361 LNETGDEPFQYKN 373


>gi|74271837 glutamine synthetase [Homo sapiens]
          Length = 373

 Score =  793 bits (2048), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60
           MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW
Sbjct: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60

Query: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120
           NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI
Sbjct: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120

Query: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180
           MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY
Sbjct: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180

Query: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240
           RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP
Sbjct: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240

Query: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300
           KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
Sbjct: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300

Query: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360
           TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL
Sbjct: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360

Query: 361 LNETGDEPFQYKN 373
           LNETGDEPFQYKN
Sbjct: 361 LNETGDEPFQYKN 373


>gi|19923206 glutamine synthetase [Homo sapiens]
          Length = 373

 Score =  793 bits (2048), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60
           MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW
Sbjct: 1   MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW 60

Query: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120
           NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI
Sbjct: 61  NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI 120

Query: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180
           MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY
Sbjct: 121 MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY 180

Query: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240
           RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP
Sbjct: 181 RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP 240

Query: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300
           KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
Sbjct: 241 KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL 300

Query: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360
           TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL
Sbjct: 301 TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL 360

Query: 361 LNETGDEPFQYKN 373
           LNETGDEPFQYKN
Sbjct: 361 LNETGDEPFQYKN 373


>gi|221307485 lengsin, lens protein with glutamine synthetase domain
           isoform a [Homo sapiens]
          Length = 509

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 16/190 (8%)

Query: 54  VEELPEWNFDGSSTLQSEGSNSDMYLVPA-AMFRDPFRKDPNKLVLCEVFKYNRRPAETN 112
           +E +P    +  + +++   NSD+ L+P  + FR     D    V+C+ F     P  T+
Sbjct: 124 LEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTGEPLLTS 183

Query: 113 LRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWP----SNGFPGPQGPYYCGVGAD 168
            R+  KR +  +  Q   F +   +     D   FG P    S     P   +      D
Sbjct: 184 PRYIAKRQLSHL--QASGFSLLSAFIY---DFCIFGVPEILNSKIISFPALTFLNN--HD 236

Query: 169 RAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRV 228
           + + +++V+  Y    + G  +   ++   P Q E    P  GIS  D+ +  R  +  V
Sbjct: 237 QPFMQELVDGLY----HTGANVESFSSSTRPGQMEISFLPEFGISSADNAFTLRTGVKEV 292

Query: 229 CEDFGVIATF 238
              +  IA+F
Sbjct: 293 ARKYNYIASF 302


>gi|58330892 interferon-induced protein with tetratricopeptide
           repeats 1-like [Homo sapiens]
          Length = 474

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 7/81 (8%)

Query: 262 REENGLKYIEEAIEKLSKR---HQYHIRAYDPKGGLDNARRLTGFH-ETSNINDF---SA 314
           +E  G KYIEEA+  +S +    QY  + Y  KG +D A  L     ET+  + F     
Sbjct: 232 QEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQM 291

Query: 315 GVANRSASIRIPRTVGQEKKG 335
           G+  R+  I+I      + +G
Sbjct: 292 GLCYRAQMIQIKEATNWQPRG 312


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 14/22 (63%), Positives = 14/22 (63%), Gaps = 1/22 (4%)

Query: 139 LMGTDGHPFGWPSNGFPGPQGP 160
           L G DG P G P  GFPGP GP
Sbjct: 687 LPGPDGEP-GIPGIGFPGPPGP 707


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 14/22 (63%), Positives = 14/22 (63%), Gaps = 1/22 (4%)

Query: 139 LMGTDGHPFGWPSNGFPGPQGP 160
           L G DG P G P  GFPGP GP
Sbjct: 687 LPGPDGEP-GIPGIGFPGPPGP 707


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 14/22 (63%), Positives = 14/22 (63%), Gaps = 1/22 (4%)

Query: 139 LMGTDGHPFGWPSNGFPGPQGP 160
           L G DG P G P  GFPGP GP
Sbjct: 687 LPGPDGEP-GIPGIGFPGPPGP 707


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 14/22 (63%), Positives = 14/22 (63%), Gaps = 1/22 (4%)

Query: 139 LMGTDGHPFGWPSNGFPGPQGP 160
           L G DG P G P  GFPGP GP
Sbjct: 687 LPGPDGEP-GIPGIGFPGPPGP 707


>gi|116534937 interferon-induced protein with tetratricopeptide
           repeats 1 isoform 2 [Homo sapiens]
          Length = 478

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 262 REENGLKYIEEAIEKLSKR---HQYHIRAYDPKGGLDNARRL 300
           +E  G KYIEEA+  +S +    +Y  + Y  KG +D A  L
Sbjct: 232 QEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALEL 273


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 3/29 (10%)

Query: 132 GMEQEYTLMGTDGHPFGWPSNGFPGPQGP 160
           G + E    G +GHP G P  GFPGP+GP
Sbjct: 45  GEKGERGFPGLEGHP-GLP--GFPGPEGP 70


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 3/29 (10%)

Query: 132 GMEQEYTLMGTDGHPFGWPSNGFPGPQGP 160
           G + E    G +GHP G P  GFPGP+GP
Sbjct: 45  GEKGERGFPGLEGHP-GLP--GFPGPEGP 70


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 3/29 (10%)

Query: 132 GMEQEYTLMGTDGHPFGWPSNGFPGPQGP 160
           G + E    G +GHP G P  GFPGP+GP
Sbjct: 45  GEKGERGFPGLEGHP-GLP--GFPGPEGP 70


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,107,891
Number of Sequences: 37866
Number of extensions: 784270
Number of successful extensions: 2032
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1930
Number of HSP's gapped (non-prelim): 112
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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