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Search of human proteins with 73486661
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73486661 amiloride binding protein 1 precursor [Homo
sapiens]
(751 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73486661 amiloride binding protein 1 precursor [Homo sapiens] 1588 0.0
gi|60498984 amine oxidase, copper containing 2 isoform b [Homo s... 544 e-154
gi|4502119 amine oxidase, copper containing 3 precursor [Homo sa... 529 e-150
gi|60498982 amine oxidase, copper containing 2 isoform a [Homo s... 509 e-144
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 32 2.2
gi|7705383 calpain 9 isoform 2 [Homo sapiens] 31 4.8
gi|5729758 calpain 9 isoform 1 [Homo sapiens] 31 4.8
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom... 31 4.8
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 30 6.3
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 30 6.3
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 30 6.3
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 30 6.3
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 30 8.2
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 30 8.2
gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo ... 30 8.2
gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo ... 30 8.2
gi|239508959 PREDICTED: hypothetical protein [Homo sapiens] 30 8.2
gi|25952092 potassium voltage-gated channel, shaker-related subf... 30 8.2
>gi|73486661 amiloride binding protein 1 precursor [Homo sapiens]
Length = 751
Score = 1588 bits (4111), Expect = 0.0
Identities = 751/751 (100%), Positives = 751/751 (100%)
Query: 1 MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS 60
MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
Sbjct: 1 MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS 60
Query: 61 TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP 120
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
Sbjct: 61 TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP 120
Query: 121 GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR 180
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
Sbjct: 121 GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR 180
Query: 181 CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG 240
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
Sbjct: 181 CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG 240
Query: 241 KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP 300
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
Sbjct: 241 KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP 300
Query: 301 RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG 360
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
Sbjct: 301 RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG 360
Query: 361 GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE 420
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
Sbjct: 361 GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE 420
Query: 421 MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH 480
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
Sbjct: 421 MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH 480
Query: 481 ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT 540
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
Sbjct: 481 ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT 540
Query: 541 NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM 600
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
Sbjct: 541 NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM 600
Query: 601 ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI 660
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
Sbjct: 601 ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI 660
Query: 661 ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD 720
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
Sbjct: 661 ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD 720
Query: 721 NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV 751
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
Sbjct: 721 NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV 751
>gi|60498984 amine oxidase, copper containing 2 isoform b [Homo
sapiens]
Length = 756
Score = 544 bits (1401), Expect = e-154
Identities = 311/738 (42%), Positives = 423/738 (57%), Gaps = 36/738 (4%)
Query: 19 AEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPK 78
A+P P P ++ +F+DLS +EL AV FL + L ++ + N +F +E+ LP
Sbjct: 44 AQPWPH--PGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPP 101
Query: 79 KYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALS-PRPGYQSS 137
K L LD+G P REA A++ FG Q PNV+E VGPLP P YMR ++ R G
Sbjct: 102 KAAALAHLDRGSPPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLP 161
Query: 138 WASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQR 197
+ RP+ AE+ ++ L+E P FL++T F++ + LA PRG+ SG R
Sbjct: 162 YHRRPVLRAEFTQMWRHLKEVELPKAPIFLSST-FNY---NGSTLAAVHATPRGLRSGDR 217
Query: 198 RSWLIIQRYVEGY--FLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYAD 255
+W+ + + G FLHP GLELL+DH + D HW V+QV+Y G +Y +L R++
Sbjct: 218 ATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKS 277
Query: 256 GEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGN 315
G ++VV + P P G SS + R P P+ P P G ++ ++GN
Sbjct: 278 GRLEVVRVPLPPPNGA-----------SSLRSRNS-PGPLP---PLQFSPQGSQYSVQGN 322
Query: 316 AVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVG 375
V+ WSF F SGL++ +V F GERIAYEVSVQE V++YG +P M T+YLD
Sbjct: 323 LVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPKTMLTRYLDSS 382
Query: 376 WGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNF 435
+GLG + L G+DCP AT +D P A+C+FE G+PLRRH N
Sbjct: 383 FGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQ 442
Query: 436 KGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYT--PE 493
+FY GL LV+R+ S+V NYDYIWDF+ YPNG +E ++HATGY++ F E
Sbjct: 443 N---HFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRVHATGYINTAFLKGGEE 499
Query: 494 GLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPT 553
GL G R+ ++G +HTH H+++DLDVAG KN + + + PW+P H + +P
Sbjct: 500 GLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQRPQ 559
Query: 554 LEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQ 613
L + E AF LP+YL S Q N WGH+R YR+QIHS +P E+
Sbjct: 560 LTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHIPLESDMER 619
Query: 614 AITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGF 673
A++W RY L VT+ +E E SSSIYHQND W P V F F+ NNE + EDLVAWVT F
Sbjct: 620 ALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFI-NNETLLGEDLVAWVTASF 678
Query: 674 LHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWP-RDNGPNYVQ--RWI 730
LHIPH+EDIPNT T GN VGFLLRP+NFF EDPS+ S +V +D G + +
Sbjct: 679 LHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSINPVACL 738
Query: 731 PEDRDCSMP--PPFSYNG 746
P+ C +P PPFSY+G
Sbjct: 739 PDLAAC-VPDLPPFSYHG 755
>gi|4502119 amine oxidase, copper containing 3 precursor [Homo
sapiens]
Length = 763
Score = 529 bits (1362), Expect = e-150
Identities = 293/736 (39%), Positives = 417/736 (56%), Gaps = 38/736 (5%)
Query: 23 PGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHV 82
P T P ++ +F+DLS +EL AV FL + L ++ + N VF +E+ LP K
Sbjct: 50 PWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAA 109
Query: 83 LRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALS-PRPGYQSSWASR 141
L LD+G P REA A++FFG Q PNV+E VGPLP P YMR ++ R G + R
Sbjct: 110 LAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRR 169
Query: 142 PISTAEYA-----LLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQ 196
P+ EY + L +A+ LH F R L APRG+ SG
Sbjct: 170 PVLFQEYLDIDQMIFNRELPQASGLLHHC-------CFYKHRGRNLVTMTTAPRGLQSGD 222
Query: 197 RRSWLIIQRYVEG--YFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYA 254
R +W + + G +FLH GLELLV+H + D W +++V+Y G++Y S +L ++
Sbjct: 223 RATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFE 282
Query: 255 DGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEG 314
G V+VV++ D GG + PP P+P P P GPRF ++G
Sbjct: 283 AGLVNVVLIPDNGTGGSWSLKSPVPP----------GPAP-----PLQFYPQGPRFSVQG 327
Query: 315 NAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDV 374
+ V W+F+F L + SG ++ +V F GER+ YE+S+QEA+A+YGG++PA M T+Y+D
Sbjct: 328 SRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDG 387
Query: 375 GWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSN 434
G+G+G T L G+DCP AT++D ++ P A C+FE G+PLRRH +
Sbjct: 388 GFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDL 447
Query: 435 FKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEG 494
+ +++ GL VLV+R+ ST+ NYDY+WD +F+P+G +E + +ATGY+ + F
Sbjct: 448 YS---HYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT 504
Query: 495 LRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTL 554
++G ++ H +G +HTH H++VDLDVAG +N M + PWSP H++ + +
Sbjct: 505 GKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQV 564
Query: 555 EQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQA 614
+ E QAAF P+YL S N WGH R YR+Q+ S A + LP +
Sbjct: 565 TRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARG 624
Query: 615 ITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFL 674
+W RY LAVT+ +E E SSS+++QNDPW P V F F+ NNE I +DLVAWVT GFL
Sbjct: 625 FSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFI-NNETIAGKDLVAWVTAGFL 683
Query: 675 HIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIV-WPRDNGPNYVQ--RWIP 731
HIPH+EDIPNT T GN VGF LRP+NFF EDPS S D++ +D G V +P
Sbjct: 684 HIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLP 743
Query: 732 EDRDCSMP-PPFSYNG 746
+ C+ P FS+ G
Sbjct: 744 QAAACAPDLPAFSHGG 759
>gi|60498982 amine oxidase, copper containing 2 isoform a [Homo
sapiens]
Length = 729
Score = 509 bits (1312), Expect = e-144
Identities = 300/738 (40%), Positives = 408/738 (55%), Gaps = 63/738 (8%)
Query: 19 AEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPK 78
A+P P P ++ +F+DLS +EL AV FL + L ++ + N +F +E+ LP
Sbjct: 44 AQPWPH--PGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPP 101
Query: 79 KYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALS-PRPGYQSS 137
K L LD+G P REA A++ FG Q PNV+E VGPLP P YMR ++ R G
Sbjct: 102 KAAALAHLDRGSPPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLP 161
Query: 138 WASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQR 197
+ RP+ AE+ ++ L+E P FL++T F++ + LA PRG+ SG R
Sbjct: 162 YHRRPVLRAEFTQMWRHLKEVELPKAPIFLSST-FNY---NGSTLAAVHATPRGLRSGDR 217
Query: 198 RSWLIIQRYVEGY--FLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYAD 255
+W+ + + G FLHP GLELL+DH + D HW V+QV+Y G +Y +L R++
Sbjct: 218 ATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKS 277
Query: 256 GEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGN 315
G ++VV + P P G SS + R P P+ P P G ++ ++GN
Sbjct: 278 GRLEVVRVPLPPPNGA-----------SSLRSRNS-PGPLP---PLQFSPQGSQYSVQGN 322
Query: 316 AVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVG 375
V+ WSF F SGL++ +V F GERIAYEVSVQE V++YG +P M T+YLD
Sbjct: 323 LVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPKTMLTRYLDSS 382
Query: 376 WGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNF 435
+GLG + L G+DCP AT +D P A+C+FE G+PLRRH N
Sbjct: 383 FGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQ 442
Query: 436 KGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYT--PE 493
+FY GL LV+R+ S+V NYDYIWDF+ YPNG +E ++HATGY++ F E
Sbjct: 443 N---HFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRVHATGYINTAFLKGGEE 499
Query: 494 GLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPT 553
GL G R+ ++G +HTH H+++DLDVAG KN + + + PW+P H + +P
Sbjct: 500 GLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQRPQ 559
Query: 554 LEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQ 613
L + E AF LP+YL S Q N WGH+R Y+
Sbjct: 560 LTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYQ------------------- 600
Query: 614 AITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGF 673
L VT+ +E E SSSIYHQND W P V F F+ NNE + EDLVAWVT F
Sbjct: 601 --------LVVTQRKEEESQSSSIYHQNDIWTPTVTFADFI-NNETLLGEDLVAWVTASF 651
Query: 674 LHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWP-RDNGPNYVQ--RWI 730
LHIPH+EDIPNT T GN VGFLLRP+NFF EDPS+ S +V +D G + +
Sbjct: 652 LHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSINPVACL 711
Query: 731 PEDRDCSMP--PPFSYNG 746
P+ C +P PPFSY+G
Sbjct: 712 PDLAAC-VPDLPPFSYHG 728
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 32.0 bits (71), Expect = 2.2
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 14/64 (21%)
Query: 256 GEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPS----PIHVSGPRLVQPHGPRFR 311
G+VDV +LE +P G G F H P+ PS + + GP+ V+ GP+
Sbjct: 1225 GQVDVKLLEGHVPEGAG---------FKGHLPKVQMPSLKMPKVDLKGPQ-VEVRGPKLD 1274
Query: 312 LEGN 315
L+G+
Sbjct: 1275 LKGH 1278
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 6/55 (10%)
Query: 252 KYADGEVDVVVLEDPLP---GGKGHDSTEEPPLFSSHKPRGDFPSP-IHVSGPRL 302
K G+VDV +LE P+P G KGH + P F P+ D P I + GP+L
Sbjct: 2211 KVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFK--VPKVDLKGPEIDIKGPKL 2263
Score = 30.8 bits (68), Expect = 4.8
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query: 257 EVDVVVLEDPLPGG---KGHDSTEEPPLFSSHKPRGDFPSP-IHVSGPRL 302
+VDV +LE P+P G KGH E P S P+ D P I V GP+L
Sbjct: 3536 QVDVELLEGPVPEGAGLKGHLPKVEMP--SLKTPKVDLKGPQIDVKGPKL 3583
Score = 30.4 bits (67), Expect = 6.3
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 256 GEVDVVVLEDPLPGG---KGHDSTEEPPLFSSHKPRGDFPSP-IHVSGPRL 302
G+VDV + E P+P G KGH + P F P+ D P I V GP+L
Sbjct: 4030 GQVDVKLPEGPVPEGASLKGHLPKVQMPSFK--MPKVDLKGPQIDVKGPKL 4078
Score = 30.0 bits (66), Expect = 8.2
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 256 GEVDVVVLEDPLPGG---KGHDSTEEPPLFSSHKPRGDFPSP-IHVSGPRL 302
G+VDV + E P+P G KGH + P F P+ D P I V GP+L
Sbjct: 2380 GQVDVKLPEGPVPEGAGLKGHLPKLQMPSFK--MPKVDLKGPQIDVKGPKL 2428
>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
Length = 664
Score = 30.8 bits (68), Expect = 4.8
Identities = 39/166 (23%), Positives = 65/166 (39%), Gaps = 10/166 (6%)
Query: 117 GPLPGPC--YMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLN--TTGF 172
G G C ++ P + S + E + L +Q+ + L +F N T G+
Sbjct: 335 GSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGY 394
Query: 173 SFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWA 232
+ +C D+ R AS R I R V F P G +L+ ST H
Sbjct: 395 AIYECPDKDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP--STFEPH-- 450
Query: 233 VEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEE 278
++ + + + + + R DG VD+ + E P P ++ EE
Sbjct: 451 -QEADFCLRIFSEKKAITRDM-DGNVDIDLPEPPKPTPPDQETEEE 494
>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
Length = 690
Score = 30.8 bits (68), Expect = 4.8
Identities = 39/166 (23%), Positives = 65/166 (39%), Gaps = 10/166 (6%)
Query: 117 GPLPGPC--YMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLN--TTGF 172
G G C ++ P + S + E + L +Q+ + L +F N T G+
Sbjct: 361 GSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRFGANVLTIGY 420
Query: 173 SFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWA 232
+ +C D+ R AS R I R V F P G +L+ ST H
Sbjct: 421 AIYECPDKDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP--STFEPH-- 476
Query: 233 VEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEE 278
++ + + + + + R DG VD+ + E P P ++ EE
Sbjct: 477 -QEADFCLRIFSEKKAITRDM-DGNVDIDLPEPPKPTPPDQETEEE 520
>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
sapiens]
Length = 802
Score = 30.8 bits (68), Expect = 4.8
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 16/131 (12%)
Query: 223 HGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLF 282
HGS W +V+ + G PE A G+V V E L STEEP +
Sbjct: 130 HGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQV---VQEQAL-------STEEPRVE 179
Query: 283 SSHKPRGDFPSPIH--VSGPRLVQPHGPRFRLEGN----AVLYGGWSFAFRLRSSSGLQV 336
S R P S L+ RL N A++ G + A R +SG++
Sbjct: 180 LSGSTRVSLEGPERRRFSASELMTRLHSSLRLGRNSAARALISGSGTGAAREGKASGMEA 239
Query: 337 LNVHFGGERIA 347
+V G+R++
Sbjct: 240 RSVEMSGDRVS 250
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 30.4 bits (67), Expect = 6.3
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 68 TVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRA 127
T ++E LLP +V R + + RE VI Q HP + + PLPG + +
Sbjct: 1566 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHP---QSPLCPLPGSAFTLS 1622
Query: 128 LSPRPG 133
PG
Sbjct: 1623 TPSAPG 1628
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 30.4 bits (67), Expect = 6.3
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 68 TVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRA 127
T ++E LLP +V R + + RE VI Q HP + + PLPG + +
Sbjct: 1583 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHP---QSPLCPLPGSAFTLS 1639
Query: 128 LSPRPG 133
PG
Sbjct: 1640 TPSAPG 1645
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 30.4 bits (67), Expect = 6.3
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 68 TVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRA 127
T ++E LLP +V R + + RE VI Q HP + + PLPG + +
Sbjct: 1513 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHP---QSPLCPLPGSAFTLS 1569
Query: 128 LSPRPG 133
PG
Sbjct: 1570 TPSAPG 1575
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 30.4 bits (67), Expect = 6.3
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 41 LKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGE--RHPVREAR 98
L+AV + S +L +T +AKN + + L + ++ FL++G+ PV A
Sbjct: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAP 182
Query: 99 AVIFFGDQEHPNVTEFAVGPLPGPC 123
F P A+GP P C
Sbjct: 183 LTPFGQATVCPFSAGAALGPCPDKC 207
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 30.0 bits (66), Expect = 8.2
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 360 GGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCP-------ETATF-LDTFHYYDADDPVH 411
GG G + + + G + HEL PG +C ET F + A +PVH
Sbjct: 4550 GGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVH 4609
Query: 412 YPRALCLFEMPTGVP 426
P+ + L E P VP
Sbjct: 4610 LPQTVRLAEPPKPVP 4624
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 30.0 bits (66), Expect = 8.2
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 360 GGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCP-------ETATF-LDTFHYYDADDPVH 411
GG G + + + G + HEL PG +C ET F + A +PVH
Sbjct: 4550 GGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVH 4609
Query: 412 YPRALCLFEMPTGVP 426
P+ + L E P VP
Sbjct: 4610 LPQTVRLAEPPKPVP 4624
>gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo
sapiens]
Length = 528
Score = 30.0 bits (66), Expect = 8.2
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 283 SSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFG 342
SS +GDF +P+ + P V+PH +EG W+ AF R L V + G
Sbjct: 8 SSSFNKGDFAAPVELLPP--VEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVAKLVAG 65
Query: 343 GERIAYEVSVQEAV 356
E A V V AV
Sbjct: 66 REGEAQPVLVPIAV 79
>gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo
sapiens]
Length = 528
Score = 30.0 bits (66), Expect = 8.2
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 283 SSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFG 342
SS +GDF +P+ + P V+PH +EG W+ AF R L V + G
Sbjct: 8 SSSFNKGDFAAPVELLPP--VEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVAKLVAG 65
Query: 343 GERIAYEVSVQEAV 356
E A V V AV
Sbjct: 66 REGEAQPVLVPIAV 79
>gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]
Length = 528
Score = 30.0 bits (66), Expect = 8.2
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 283 SSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFG 342
SS +GDF +P+ + P V+PH +EG W+ AF R L V + G
Sbjct: 8 SSSFNKGDFAAPVELLPP--VEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVAKLVAG 65
Query: 343 GERIAYEVSVQEAV 356
E A V V AV
Sbjct: 66 REGEAQPVLVPIAV 79
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 30.0 bits (66), Expect = 8.2
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 2/83 (2%)
Query: 256 GEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQP-HGPRFRLEG 314
G +L DP G+ +D F H+P D + SG RL +P H P
Sbjct: 32 GRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLE 91
Query: 315 NAVLYG-GWSFAFRLRSSSGLQV 336
YG G + RLR G V
Sbjct: 92 EVAFYGLGAAALARLREDEGCPV 114
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,236,849
Number of Sequences: 37866
Number of extensions: 1765907
Number of successful extensions: 3445
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3402
Number of HSP's gapped (non-prelim): 35
length of query: 751
length of database: 18,247,518
effective HSP length: 110
effective length of query: 641
effective length of database: 14,082,258
effective search space: 9026727378
effective search space used: 9026727378
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.