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Search of human proteins with 72534784
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo
sapiens]
(379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo sa... 754 0.0
gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo sa... 363 e-100
gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens] 231 8e-61
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 49 1e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 49 1e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 47 2e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 47 2e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 47 2e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 47 2e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 47 2e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 47 2e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 47 2e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 47 2e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 47 3e-05
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 47 3e-05
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 47 3e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 47 3e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 47 3e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 46 5e-05
gi|148746195 trichohyalin [Homo sapiens] 46 6e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 8e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 45 8e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 1e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 1e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 1e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 1e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 45 1e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 44 2e-04
gi|126362971 serine/threonine kinase 10 [Homo sapiens] 44 2e-04
gi|16262452 cingulin [Homo sapiens] 43 4e-04
>gi|72534784 RIB43A domain with coiled-coils 1 isoform 1 [Homo
sapiens]
Length = 379
Score = 754 bits (1948), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER
Sbjct: 1 MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
Query: 61 SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW
Sbjct: 61 SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
Query: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY
Sbjct: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
Query: 181 TDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKAN 240
TDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKAN
Sbjct: 181 TDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKAN 240
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR
Sbjct: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSV 360
QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSV
Sbjct: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSV 360
Query: 361 IYTNQPTAQYHQQFNTSSR 379
IYTNQPTAQYHQQFNTSSR
Sbjct: 361 IYTNQPTAQYHQQFNTSSR 379
>gi|21450659 RIB43A domain with coiled-coils 1 isoform 2 [Homo
sapiens]
Length = 192
Score = 363 bits (933), Expect = e-100
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER
Sbjct: 1 MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAER 60
Query: 61 SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW
Sbjct: 61 SKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVW 120
Query: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY
Sbjct: 121 KGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENY 180
Query: 181 T 181
T
Sbjct: 181 T 181
>gi|241666448 RIB43A domain with coiled-coils 2 [Homo sapiens]
Length = 377
Score = 231 bits (589), Expect = 8e-61
Identities = 135/371 (36%), Positives = 208/371 (56%), Gaps = 1/371 (0%)
Query: 9 DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
D ++ A + RR+ E RQ R FN RNR++G D +A + QV D+K +EA E+++ +
Sbjct: 8 DLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAA 67
Query: 69 SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
Q D ++ +LE + + L + + +F++ Q+ + REF L DP + K LP S
Sbjct: 68 EMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQS 127
Query: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQL 188
++ + +Q F GEDL+ R + Q+ Q R +QQ+E + A+ ++ +AL +
Sbjct: 128 DNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTET 187
Query: 189 RLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQS 248
RL D A HL +LE + R A+ ++ + NK+QA R++ E+++EQ+ NLAEI +
Sbjct: 188 RLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLL 247
Query: 249 TSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDT 308
DLL+ENPQ A P+RV+P WKGMT EQ IR Q+ Q +K ++ ++ D
Sbjct: 248 RGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDL 307
Query: 309 EWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTA 368
+W + + A+A L E Q+ +R L S N LA EQ Q+ Y+N V YTNQPT
Sbjct: 308 DWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEV-YTNQPTG 366
Query: 369 QYHQQFNTSSR 379
Y QFNT SR
Sbjct: 367 DYFTQFNTGSR 377
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 1e-05
Identities = 62/289 (21%), Positives = 121/289 (41%), Gaps = 30/289 (10%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + Q+ K+REA + + +Q++ L K++AD +L +++ + KQ
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQ 1219
Query: 104 QLKNGREFSLWDPGQVWKGLPTY-LSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRY 162
+L+ + + + + S SN +++ E +D QQ Q +
Sbjct: 1220 KLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDE----QQTQLIH 1275
Query: 163 NLERQQQEQQQAKVDENY----TDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANAN 218
+L Q+ Q + ++ ++L +QL + A L L+ A A+
Sbjct: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335
Query: 219 KAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMT 278
A+Q+ R C+ REQ E + + L N +VAQ W+ T
Sbjct: 1336 ----ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQ------------WR--T 1377
Query: 279 PEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQ 327
+ AI++ +E++ +KK + A++ + E ++T +S A LE +Q
Sbjct: 1378 KYETDAIQRTEELEEAKK---KLAQRLQEAEENTETANSKCASLEKTKQ 1423
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/292 (23%), Positives = 125/292 (42%), Gaps = 44/292 (15%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + Q+ K+REA + + +Q++ L K+ AD +L +++ + KQ
Sbjct: 1158 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1217
Query: 104 QL-KNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSG--EDLDRDTRLRMQQGQF 160
+L K EF L + V + + A+L+ S ED + R+++++ Q
Sbjct: 1218 KLEKEKSEFKL-ELDDVTSNMEQIIK------AKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 161 RYNLERQQQEQQQAKVDE-----NYTDALSNQL---RLAMDAQATHLAR-LEESCRAAMM 211
N Q+ + Q + E +AL +QL +L+ Q L R LEE +A
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK-- 1328
Query: 212 CAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLP 271
N A+Q+ R C+ REQ E + + L N +VAQ
Sbjct: 1329 ------NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ---------- 1372
Query: 272 YCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE 323
W+ T + AI++ +E++ +KK + A++ D E + +++ + LE
Sbjct: 1373 --WR--TKYETDAIQRTEELEEAKK---KLAQRLQDAEEAVEAVNAKCSSLE 1417
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2094
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2095 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2155 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2190
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2176
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2177 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2230
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2231 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2286
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2287 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2346
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2347 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2442
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1401
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1402 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1515
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1516 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1569
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1570 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1614
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1615 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1673
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1674 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1673
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1674 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1733
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1734 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1784
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1785 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1841
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1842 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1900
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1901 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1959
Query: 358 NS 359
S
Sbjct: 1960 RS 1961
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1812 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1871
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1872 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1931
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1992 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2051
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2052 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2098
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2099 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2158
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2159 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2194
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2180
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2181 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2234
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2235 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2290
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2291 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2350
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2351 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2410 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2446
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1346 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1405
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1406 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1459
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1460 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1519
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1520 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1573
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1574 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1618
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1619 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1677
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1678 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1710
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1620 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1677
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1678 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1737
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1738 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1788
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1789 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1845
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1846 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1904
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1905 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1963
Query: 358 NS 359
S
Sbjct: 1964 RS 1965
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2094
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2095 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2154
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2155 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2190
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2176
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2177 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2230
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2231 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2286
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2287 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2346
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2347 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2442
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1401
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1402 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1515
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1516 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1569
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1570 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1614
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1615 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1673
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1674 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1673
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1674 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1733
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1734 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1784
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1785 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1841
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1842 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1900
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1901 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1959
Query: 358 NS 359
S
Sbjct: 1960 RS 1961
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1776 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1835
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1836 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1895
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1896 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1955
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1956 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2015
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2016 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2062
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2063 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2122
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2123 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2158
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2144
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2145 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2198
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2199 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2254
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2255 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2314
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2315 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2373
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2374 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2410
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1310 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1369
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1370 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1423
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1424 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1483
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1484 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1537
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1538 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1582
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1583 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1641
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1642 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1674
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1584 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1641
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1642 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1701
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1702 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1752
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1753 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1809
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1810 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1868
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1869 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1927
Query: 358 NS 359
S
Sbjct: 1928 RS 1929
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1945 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 2004
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 2005 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 2064
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 2065 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2124
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 2125 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2184
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2185 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2231
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2232 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2291
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2292 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2327
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2313
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2314 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2367
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2368 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2423
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2424 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2483
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2484 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2542
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2543 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2579
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1479 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1538
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1539 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1592
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1593 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1652
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1653 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1706
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1707 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1751
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1752 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1810
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1811 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1843
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1753 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1810
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1811 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1870
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1871 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1921
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1922 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1978
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1979 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 2037
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 2038 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 2096
Query: 358 NS 359
S
Sbjct: 2097 RS 2098
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1786 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1845
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1846 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1905
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1906 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1965
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1966 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2025
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2026 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2072
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2073 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2132
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2133 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2168
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2154
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2155 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2208
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2209 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2264
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2265 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2324
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2325 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2383
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2384 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2420
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1320 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1379
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1380 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1433
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1434 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1493
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1494 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1547
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1548 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1592
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1593 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1651
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1652 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1684
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1594 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1651
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1652 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1711
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1712 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1762
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1763 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1819
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1820 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1878
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1879 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1937
Query: 358 NS 359
S
Sbjct: 1938 RS 1939
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1794 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1853
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1854 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1913
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1914 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1973
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 1974 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2033
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2034 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2080
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2081 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2140
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2141 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2176
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2103 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2162
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2163 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2216
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2217 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2272
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2273 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2332
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2333 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2391
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2392 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2428
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1328 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1387
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1388 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1441
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1442 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1501
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1502 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1555
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1556 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1600
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1601 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1659
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1660 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1692
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1602 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1659
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1660 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1719
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1720 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1770
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1771 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1827
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1828 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1886
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1887 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1945
Query: 358 NS 359
S
Sbjct: 1946 RS 1947
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/397 (20%), Positives = 160/397 (40%), Gaps = 47/397 (11%)
Query: 13 AAAIEARRNRE--KERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT-S 69
A A EA+R R+ +E R RV+ + A+ + E A + KEA
Sbjct: 1835 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1894
Query: 70 QVQYDVVVQM--LEKEEADRTRQLAKKVQEFRE----QKQQLKNGREFSLWDPGQVWKG- 122
++ D Q LE++ A + +++ + R+ + ++ K E +L QV +
Sbjct: 1895 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1954
Query: 123 LPTYLSYSNTYPGPASLQYFSGEDLDR--DTRLRMQQGQFRYNLERQ---QQEQQQAKVD 177
L S+ G A L+ G DT +Q + +RQ ++E+++ + +
Sbjct: 1955 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2014
Query: 178 ENYTDALS------NQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
E +L+ Q + A++ A++EE+ R +A + Q A +A ++R
Sbjct: 2015 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2074
Query: 232 E----------RQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
+ +Q+EQ+ Q QS D L + A+ + +
Sbjct: 2075 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAAR-------------RAAEEAE 2121
Query: 282 QAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE--LEEQERELCAVFQRGL 339
+A ++ E+E +S++Q E ++Q + AQA E +E E+E Q
Sbjct: 2122 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQ 2181
Query: 340 GSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNT 376
+ Q+ A + + ++ + T + AQ Q+ T
Sbjct: 2182 AALRQKQAADAEMEK-HKKFAEQTLRQKAQVEQELTT 2217
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/337 (21%), Positives = 124/337 (36%), Gaps = 21/337 (6%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
+KQS + + A +A+ EK R+ R Q D + + + +++
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQ 2203
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+QV+ ++ L+ EE D + L E+ Q+LK + QV + L
Sbjct: 2204 TLRQKAQVEQELTTLRLQLEETDHQKNL------LDEELQRLKAEATEAARQRSQVEEEL 2257
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
+ S E +R LR + R+ E ++ +Q A+ + A
Sbjct: 2258 FSV----RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVA 2313
Query: 184 LSNQLRLAMDAQ--ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
RL A+ L E M A+ A + +A + +Q+ E +EQ L
Sbjct: 2314 AQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2373
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG--------MTPEQQAAIRKEQEVQR 293
E + Q L E Q Q + R + +A R E++ QR
Sbjct: 2374 QEDKEQMAQQ-LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2432
Query: 294 SKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+KQA EK TE +Q + LE++ Q+ +
Sbjct: 2433 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSD 2469
Score = 43.1 bits (100), Expect = 4e-04
Identities = 84/395 (21%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQAL---NNQVGDRKRREAAERSKEAAYGTSQVQYDV 75
RR E+ER R +V+A Q+ + + A+ +EA ++Q +V
Sbjct: 1369 RRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEV 1428
Query: 76 VVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKG------------- 122
V +EEA Q K+ +E+ QQL+ E + + +
Sbjct: 1429 V----RREEAAVDAQQQKR--SIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1482
Query: 123 -LPTYLSYSNTYPGPAS--LQYFSGEDLDRDTRLRMQQGQ---FRYNLERQQQEQQQAKV 176
+ L + G A LQ + + + R Q + R ++ + Q ++QA+V
Sbjct: 1483 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEV 1542
Query: 177 DENYTDALSNQLRLAMDA--------QATHLARL--EESCRAAMMCAMANANKAQAAVQA 226
+ L+++++ +A QA RL EE+ R + A + Q A++
Sbjct: 1543 E------LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1596
Query: 227 GRQRCERQREQK-ANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAI 285
++ E + + K A+ AE Q L E+ VAQ + E +
Sbjct: 1597 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ---------------LREEAERRA 1641
Query: 286 RKEQEVQRSKKQAHRQAEK-----------TLDTEWKSQTMSSAQAVLELEEQERELCAV 334
+++ E +R++++A R+ E+ L E +Q S AQA E +++E E A
Sbjct: 1642 QQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA- 1700
Query: 335 FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
R G +Q +++ + L + TAQ
Sbjct: 1701 --RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1733
Score = 37.7 bits (86), Expect = 0.017
Identities = 77/362 (21%), Positives = 138/362 (38%), Gaps = 29/362 (8%)
Query: 11 KEAAAIEARRNREKE------RQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEA 64
++A A AR E+E + N +R + V Q Q K++E AER EA
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAER--EA 1700
Query: 65 AYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLP 124
+ V + L ++E ++ RQLA+ + R +Q Q + L
Sbjct: 1701 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE 1760
Query: 125 TYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDAL 184
L A LQ + + L + + R +E + +A+ + T
Sbjct: 1761 EEL---------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1811
Query: 185 SNQLRLAMDAQATHLARL-EESCRAAMMCAMANANKAQAAVQAGRQRCERQR---EQKAN 240
S Q ++A+A L EE+ R + A + A A RQR E +R E+ A
Sbjct: 1812 SKQ---RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1868
Query: 241 LAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR 300
+ E T + + A++ ++ E+QAA K +++ Q +
Sbjct: 1869 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK-ADIEERLAQLRK 1927
Query: 301 QAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQR---GLGSFNQQLANEQKAQQDYL 357
++ L+ + K + + ++EE+ L A F++ G +L + +D L
Sbjct: 1928 ASDSELERQ-KGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1986
Query: 358 NS 359
S
Sbjct: 1987 RS 1988
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 47.0 bits (110), Expect = 3e-05
Identities = 92/381 (24%), Positives = 156/381 (40%), Gaps = 74/381 (19%)
Query: 12 EAAAIEARRNREKERQNRF-FNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
+AA EA+ + E ER R + R +G +++AL ++ D A++ +
Sbjct: 1142 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS------ 1195
Query: 71 VQYDVVVQMLEKEEADRTRQLAKKVQEFR-----------EQKQQLKNGREFSLWDPGQV 119
+ + V L+K + TR VQE R EQ +Q + G+ W+ +
Sbjct: 1196 -KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK--GAWEKTR- 1251
Query: 120 WKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQ----QGQF----RYNLERQQQEQ 171
L S +SLQ E R RL +Q QG+ R E ++ Q
Sbjct: 1252 ---LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
Query: 172 QQAKVDENYTDAL----SNQLRLAMDAQAT----HLAR--LEESCRAAMMCAMANANKAQ 221
+ EN + AL S +RL+ + +T H A+ L+E RA + A+ + +A
Sbjct: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL--ALGSRVRAM 1366
Query: 222 AAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
A AG REQ A + ++ +L T Q+++ W+ E+
Sbjct: 1367 EAEAAGL------REQLEEEAAARERAGRELQTAQAQLSE------------WRRRQEEE 1408
Query: 282 QAAIRKEQEVQR-----SKKQAHRQAEKT-----LDTEWKSQTMSSAQAVLELEEQEREL 331
A+ +E +R ++ R AEKT L+ + A ++LE+Q R+L
Sbjct: 1409 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-RQL 1467
Query: 332 CAVFQRGLGSFNQQLANEQKA 352
+ ++ F+Q LA E+ A
Sbjct: 1468 VSTLEKKQRKFDQLLAEEKAA 1488
Score = 32.3 bits (72), Expect = 0.72
Identities = 62/268 (23%), Positives = 104/268 (38%), Gaps = 38/268 (14%)
Query: 17 EARRNREKE-RQNRFFNVRNRVMGVDVQALNNQ----VGDRKRREAAERSKEAAYGTSQV 71
E R +RE+ QNR R+ G++ + L Q DR RR+A + E A +
Sbjct: 1688 ETRTSREEIFSQNR--ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1745
Query: 72 QYDVVVQMLEKEEAD-RTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
+ EK + + R QL ++++E + +L N R L QV + L T LS
Sbjct: 1746 NLSKAAILEEKRQLEGRLGQLEEELEE-EQSNSELLNDRYRKLLL--QV-ESLTTELSAE 1801
Query: 131 NTYPGPAS---------LQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYT 181
++ A +Q G + D R + LE + + ++ E
Sbjct: 1802 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1861
Query: 182 DALSNQL-RLAMDAQATHLARLEESCRAA----------------MMCAMANANKAQAAV 224
LS +L R A + ++EE R A + + A + +
Sbjct: 1862 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1921
Query: 225 QAGRQRCERQREQKANLAEIQHQSTSDL 252
QAGR+R +R+ E AE ++ + L
Sbjct: 1922 QAGRRRLQRELEDVTESAESMNREVTTL 1949
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 47.0 bits (110), Expect = 3e-05
Identities = 92/381 (24%), Positives = 156/381 (40%), Gaps = 74/381 (19%)
Query: 12 EAAAIEARRNREKERQNRF-FNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
+AA EA+ + E ER R + R +G +++AL ++ D A++ +
Sbjct: 1134 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS------ 1187
Query: 71 VQYDVVVQMLEKEEADRTRQLAKKVQEFR-----------EQKQQLKNGREFSLWDPGQV 119
+ + V L+K + TR VQE R EQ +Q + G+ W+ +
Sbjct: 1188 -KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK--GAWEKTR- 1243
Query: 120 WKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQ----QGQF----RYNLERQQQEQ 171
L S +SLQ E R RL +Q QG+ R E ++ Q
Sbjct: 1244 ---LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300
Query: 172 QQAKVDENYTDAL----SNQLRLAMDAQAT----HLAR--LEESCRAAMMCAMANANKAQ 221
+ EN + AL S +RL+ + +T H A+ L+E RA + A+ + +A
Sbjct: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL--ALGSRVRAM 1358
Query: 222 AAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
A AG REQ A + ++ +L T Q+++ W+ E+
Sbjct: 1359 EAEAAGL------REQLEEEAAARERAGRELQTAQAQLSE------------WRRRQEEE 1400
Query: 282 QAAIRKEQEVQR-----SKKQAHRQAEKT-----LDTEWKSQTMSSAQAVLELEEQEREL 331
A+ +E +R ++ R AEKT L+ + A ++LE+Q R+L
Sbjct: 1401 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-RQL 1459
Query: 332 CAVFQRGLGSFNQQLANEQKA 352
+ ++ F+Q LA E+ A
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAA 1480
Score = 32.3 bits (72), Expect = 0.72
Identities = 62/268 (23%), Positives = 104/268 (38%), Gaps = 38/268 (14%)
Query: 17 EARRNREKE-RQNRFFNVRNRVMGVDVQALNNQ----VGDRKRREAAERSKEAAYGTSQV 71
E R +RE+ QNR R+ G++ + L Q DR RR+A + E A +
Sbjct: 1680 ETRTSREEIFSQNR--ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1737
Query: 72 QYDVVVQMLEKEEAD-RTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
+ EK + + R QL ++++E + +L N R L QV + L T LS
Sbjct: 1738 NLSKAAILEEKRQLEGRLGQLEEELEE-EQSNSELLNDRYRKLLL--QV-ESLTTELSAE 1793
Query: 131 NTYPGPAS---------LQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYT 181
++ A +Q G + D R + LE + + ++ E
Sbjct: 1794 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1853
Query: 182 DALSNQL-RLAMDAQATHLARLEESCRAA----------------MMCAMANANKAQAAV 224
LS +L R A + ++EE R A + + A + +
Sbjct: 1854 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1913
Query: 225 QAGRQRCERQREQKANLAEIQHQSTSDL 252
QAGR+R +R+ E AE ++ + L
Sbjct: 1914 QAGRRRLQRELEDVTESAESMNREVTTL 1941
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 47.0 bits (110), Expect = 3e-05
Identities = 92/381 (24%), Positives = 156/381 (40%), Gaps = 74/381 (19%)
Query: 12 EAAAIEARRNREKERQNRF-FNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ 70
+AA EA+ + E ER R + R +G +++AL ++ D A++ +
Sbjct: 1175 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS------ 1228
Query: 71 VQYDVVVQMLEKEEADRTRQLAKKVQEFR-----------EQKQQLKNGREFSLWDPGQV 119
+ + V L+K + TR VQE R EQ +Q + G+ W+ +
Sbjct: 1229 -KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK--GAWEKTR- 1284
Query: 120 WKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQ----QGQF----RYNLERQQQEQ 171
L S +SLQ E R RL +Q QG+ R E ++ Q
Sbjct: 1285 ---LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
Query: 172 QQAKVDENYTDAL----SNQLRLAMDAQAT----HLAR--LEESCRAAMMCAMANANKAQ 221
+ EN + AL S +RL+ + +T H A+ L+E RA + A+ + +A
Sbjct: 1342 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKL--ALGSRVRAM 1399
Query: 222 AAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQ 281
A AG REQ A + ++ +L T Q+++ W+ E+
Sbjct: 1400 EAEAAGL------REQLEEEAAARERAGRELQTAQAQLSE------------WRRRQEEE 1441
Query: 282 QAAIRKEQEVQR-----SKKQAHRQAEKT-----LDTEWKSQTMSSAQAVLELEEQEREL 331
A+ +E +R ++ R AEKT L+ + A ++LE+Q R+L
Sbjct: 1442 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQ-RQL 1500
Query: 332 CAVFQRGLGSFNQQLANEQKA 352
+ ++ F+Q LA E+ A
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAA 1521
Score = 32.3 bits (72), Expect = 0.72
Identities = 62/268 (23%), Positives = 104/268 (38%), Gaps = 38/268 (14%)
Query: 17 EARRNREKE-RQNRFFNVRNRVMGVDVQALNNQ----VGDRKRREAAERSKEAAYGTSQV 71
E R +RE+ QNR R+ G++ + L Q DR RR+A + E A +
Sbjct: 1721 ETRTSREEIFSQNR--ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1778
Query: 72 QYDVVVQMLEKEEAD-RTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYS 130
+ EK + + R QL ++++E + +L N R L QV + L T LS
Sbjct: 1779 NLSKAAILEEKRQLEGRLGQLEEELEE-EQSNSELLNDRYRKLLL--QV-ESLTTELSAE 1834
Query: 131 NTYPGPAS---------LQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYT 181
++ A +Q G + D R + LE + + ++ E
Sbjct: 1835 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1894
Query: 182 DALSNQL-RLAMDAQATHLARLEESCRAA----------------MMCAMANANKAQAAV 224
LS +L R A + ++EE R A + + A + +
Sbjct: 1895 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1954
Query: 225 QAGRQRCERQREQKANLAEIQHQSTSDL 252
QAGR+R +R+ E AE ++ + L
Sbjct: 1955 QAGRRRLQRELEDVTESAESMNREVTTL 1982
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 47.0 bits (110), Expect = 3e-05
Identities = 63/292 (21%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 90 QLAKKVQEFREQKQQLKN-GREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLD 148
QLA+K+Q+ ++Q+QQ ++ + ++ Q G+ T + P P L S
Sbjct: 3729 QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALG---PKPQGLMPPSS---- 3781
Query: 149 RDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRA 208
QG L Q + Q + L Q A+ Q H L R
Sbjct: 3782 -------HQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRV 3834
Query: 209 AMMCAMANANK---AQAAVQAGRQRCERQREQKANLAEIQHQSTSDLL-TENPQVAQHPM 264
+A + V A +Q+ ++Q +Q+ ++A + H S + + P+++ PM
Sbjct: 3835 LSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPM 3894
Query: 265 APYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMS---SAQAV 321
+ L +QQ ++++Q++Q+ ++Q +Q ++ + + Q Q
Sbjct: 3895 GSLQQL---------QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Query: 322 LELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQ 373
+L++Q+++L Q+ F QQ +Q+ Q LN P Q QQ
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQ---QQQQQMGLLNQSRTLLSPQQQQQQQ 3994
Score = 30.4 bits (67), Expect = 2.7
Identities = 61/285 (21%), Positives = 109/285 (38%), Gaps = 27/285 (9%)
Query: 100 EQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQ 159
+Q+QQ +G SL P + P L+ + P LQ +R +L+ Q+ Q
Sbjct: 3679 QQQQQQHSGGAGSLAGPSGGF--FPGNLALRSLGPDSRLLQ-------ERQLQLQQQRMQ 3729
Query: 160 FRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANK 219
L++QQQ+QQQ + L Q+ + Q + ++ M ++
Sbjct: 3730 LAQKLQQQQQQQQQQQ-------HLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSH 3782
Query: 220 AQAAVQAGRQRCERQRE---QKANLAEIQHQSTSDLLTENPQ----VAQHPMAPYRVLPY 272
VQ + + + A +A +Q Q L + P + Q + L
Sbjct: 3783 QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQ 3842
Query: 273 CWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKS---QTMSSAQAVLELEE-QE 328
+G+ + +++Q+ Q+ ++Q L S Q SAQ + L++ Q+
Sbjct: 3843 QGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902
Query: 329 RELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQ 373
++ Q+ QQL +Q+ QQ L Q Q QQ
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 47.0 bits (110), Expect = 3e-05
Identities = 62/289 (21%), Positives = 119/289 (41%), Gaps = 30/289 (10%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + QV K+REA + + +Q++ +V L K+ AD +L +++ + KQ
Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ 1218
Query: 104 QLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYN 163
+L+ + + L + + G S ED + + + ++ Q N
Sbjct: 1219 KLEKEKSELKMETDD----LSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIN 1274
Query: 164 LERQQQEQQQAKVDE-----NYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANAN 218
Q+ + Q + E + DAL +QL + A + L+ A A+
Sbjct: 1275 DLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAH 1334
Query: 219 KAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMT 278
A+Q+ R C+ REQ E + + L N +VAQ W+ T
Sbjct: 1335 ----ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ------------WR--T 1376
Query: 279 PEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQ 327
+ AI++ +E++ +KK + A++ + E + +++ A LE +Q
Sbjct: 1377 KYETDAIQRTEELEEAKK---KLAQRLQEAEEHVEAVNAKCASLEKTKQ 1422
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 46.2 bits (108), Expect = 5e-05
Identities = 71/298 (23%), Positives = 121/298 (40%), Gaps = 52/298 (17%)
Query: 46 NNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQL 105
+ Q+ K+REA + +Q++ +V L K+ AD +L +++ + KQ+L
Sbjct: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
Query: 106 -KNGREFSLW------DPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRD-------- 150
K EF L V K T S E++ R
Sbjct: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278
Query: 151 TRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLAR-LEESCRAA 209
+RL+ + G+ L RQ +E+ E+ LS + A Q L R LEE +A
Sbjct: 1279 SRLQTEAGE----LSRQLEEK------ESIVSQLSRS-KQAFTQQTEELKRQLEEENKAK 1327
Query: 210 MMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRV 269
N A+Q+ R C+ REQ E + + L N +VAQ
Sbjct: 1328 --------NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ-------- 1371
Query: 270 LPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQ 327
W+ T + AI++ +E++ +KK + A++ D+E + + +++ A LE +Q
Sbjct: 1372 ----WR--TKYETDAIQRTEELEEAKK---KLAQRLQDSEEQVEAVNAKCASLEKTKQ 1420
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.8 bits (107), Expect = 6e-05
Identities = 68/345 (19%), Positives = 137/345 (39%), Gaps = 32/345 (9%)
Query: 20 RNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQM 79
++R +E R F R+R L + G R+R++ E+ +E A G Q + ++
Sbjct: 111 QDRRQEEDQRRFEPRDR-------QLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163
Query: 80 LEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASL 139
+++ D +L ++ QE++E++++ + Q KG T +P L
Sbjct: 164 RDRQRRDE--ELWRQRQEWQEREERRAEEEQL------QSCKGHET-----EEFPDEEQL 210
Query: 140 QYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQA---------KVDENYTDALSNQLRL 190
+ +L R R QQ Q R +R QE+++ + +E Q +
Sbjct: 211 RRRELLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 191 AMDAQATHLARLE-ESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQST 249
+ + L +LE + R + + Q R++ E +REQ+ E Q +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE-QQERR 328
Query: 250 SDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTE 309
Q + R + ++ +R+EQE +R ++Q R+ + + +
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 310 WKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQ 354
+ + + L E+Q R + + QQL EQ+ ++
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Score = 41.2 bits (95), Expect = 0.002
Identities = 79/380 (20%), Positives = 150/380 (39%), Gaps = 35/380 (9%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E ++ R +ER+ + R+R + Q L+ Q DRK RE ++ + ++ +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE-- 1452
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
Q L +E + R+ + +QE RE++Q + R+ + Q + +
Sbjct: 1453 -QQLRQERHRKFREEEQLLQE-REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ---E 1507
Query: 137 ASLQYFSGEDLDRDTRLRMQQGQFRYNLE----RQQQEQQQAKVDENYTDALSNQLRLAM 192
Q + L+ + +L QQ Q ++ E R+Q+ QQ + D + QLR
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 193 DAQ------ATHLARLEE-SCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAE-- 243
+ Q RLEE R ++ Q Q G+Q+ ++R++K E
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 244 IQHQSTSDL---------LTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRS 294
+Q + L L E PQ+ + K EQ +EQ+++R
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 295 KK-QAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQ 353
++ + R+ E+ L + + + + L +E ER+ R Q+ EQ +
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF-----REEEQLRQETEQEQLRR 1742
Query: 354 QDYLNSVIYTNQPTAQYHQQ 373
Q+ ++ Q + +Q
Sbjct: 1743 QERYRKILEEEQLRPEREEQ 1762
Score = 39.3 bits (90), Expect = 0.006
Identities = 71/368 (19%), Positives = 128/368 (34%), Gaps = 55/368 (14%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E R+ R K Q R + V+ + R +RE E + S+ Q +
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNG-----REFSLWDPGQ------VWKGLPT 125
Q L +E+ +R Q K+ +E +Q+LK RE L + Q + +P
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Query: 126 YLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLE------------RQQQEQQQ 173
+ + + +S R R +Q + R E RQQQE++Q
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 174 AK--VDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRC 231
+ + + S + R + A+ + E RA + + R+R
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 232 ERQREQKANLAE----IQHQSTSDLLTENPQVAQHPMAPYR------------------- 268
R+RE++ E +Q + + L E Q R
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 269 -------VLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAV 321
P + + EQQ +E+E+QR +++ R+ E+ + Q + +
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Query: 322 LELEEQER 329
L E ++R
Sbjct: 944 LREEREKR 951
Score = 39.3 bits (90), Expect = 0.006
Identities = 74/345 (21%), Positives = 132/345 (38%), Gaps = 50/345 (14%)
Query: 22 REKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLE 81
+E+E Q R+R + Q L Q DRK RE RS+E + ++ Q L
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE-----PERKFLEEEQQLH 1525
Query: 82 KEEADRTRQLAKKVQEFREQK--QQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASL 139
+++ R R+ ++ Q+ R Q+ QQ + R+ + Q+ + L
Sbjct: 1526 RQQ--RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 140 -------QYFSGEDLDRDTRLRMQQGQFRYNLER-----------QQQEQQQAKVDENYT 181
Q + ++ + +LR Q+GQ + ER Q++E+QQ E
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 182 DALSNQLRLAMDAQATHLAR------------LEESCRAAMMCAMANANKAQAAVQAGRQ 229
L + +L + L L+E + + + Q RQ
Sbjct: 1644 KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 230 RCER---QREQKANLAEIQH--QSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAA 284
ER Q EQ+ E++ + L E Q YR K + EQ
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR------KILEEEQLRP 1757
Query: 285 IRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQER 329
R+EQ+++R ++ + E+ L E + Q + S ++ + E+E+
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Score = 38.1 bits (87), Expect = 0.013
Identities = 57/316 (18%), Positives = 120/316 (37%), Gaps = 55/316 (17%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E ++ + +ERQ+R F + + + ++ + E +R +E Q++
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR---- 279
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
LE++E R RQ ++ Q+ ++QQL+ +E + +
Sbjct: 280 --KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE------------------ 319
Query: 137 ASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVD-ENYTDALSNQLRLAMDAQ 195
E ++ R Q+ + L R+Q+E+++ ++ E + QLR + +
Sbjct: 320 --------ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 196 ATHLARLEESCRAAMMCAMANANKAQAAVQAGRQ-RCERQREQKANLAEIQHQSTSDLLT 254
R E+ R + + ++ +Q R E+Q ++ L Q L
Sbjct: 372 -----RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 255 ENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQT 314
+ +H EQ+ R+EQ ++R +++ ++ +TE Q
Sbjct: 427 REQEEERHEQKH-------------EQE---RREQRLKREQEERRDWLKREEETERHEQE 470
Query: 315 MSSAQAVLELEEQERE 330
Q + EE+ RE
Sbjct: 471 RRKQQLKRDQEEERRE 486
Score = 38.1 bits (87), Expect = 0.013
Identities = 63/343 (18%), Positives = 133/343 (38%), Gaps = 45/343 (13%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
+ RR +E+ER + R Q L + +RR+ +R +E T + + +
Sbjct: 424 QLRREQEEERHEQKHEQERRE-----QRLKRE--QEERRDWLKREEE----TERHEQERR 472
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
Q L++++ + R+ K++E ++QQ + ++ + + L
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 137 ASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQA 196
S Q E +R +L ++ + R LE++++EQ+ + E D L L+ + +
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKR--LEQERREQRLKREQEERRDQL---LKREEERRQ 587
Query: 197 THLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTEN 256
L R +E + + R E +REQ+ E + + LL
Sbjct: 588 QRLKREQEE----------RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 257 PQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMS 316
Q + +Q +R+EQ+ +R ++ + E+ L+ K +
Sbjct: 638 EQEER-------------------RQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Query: 317 SAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNS 359
+ EE++ + + + + QL +E A+Q + S
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Score = 37.7 bits (86), Expect = 0.017
Identities = 66/335 (19%), Positives = 129/335 (38%), Gaps = 35/335 (10%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E RR +E ERQ R + + + L + +++RR+ ER Q + ++
Sbjct: 1129 EKRRRQELERQYR----EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
+ EK +R RQ ++ +E + QK++ + E D W+ N
Sbjct: 1185 REEQEKRRQERERQYREE-EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV--- 1240
Query: 137 ASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQA 196
Y G + ++ +L + Q R +RQ Q+ Q + E + Q R +
Sbjct: 1241 ----YCKGRENEQFRQL--EDSQLR---DRQSQQDLQHLLGEQQ-ERDREQERRRWQQRD 1290
Query: 197 THLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTEN 256
H E+ R A K+Q Q R+ ER+ +++ + + + LL E
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE--EREEKRRRQETDRKFREEEQLLQER 1348
Query: 257 PQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMS 316
+ P R E+ R+E+ + + + + E+ L + + +
Sbjct: 1349 EE------QPLR---------RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFL 1393
Query: 317 SAQAVLELEEQERELCAVFQRGLGSFNQQLANEQK 351
+ L +E+E++L R QQL+ +++
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Score = 36.6 bits (83), Expect = 0.038
Identities = 68/337 (20%), Positives = 131/337 (38%), Gaps = 63/337 (18%)
Query: 19 RRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQ 78
++ R++E++ R + R+R + Q + + KRR+ + ++
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK--------------- 1318
Query: 79 MLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPAS 138
L +EE + R+ + ++FRE++Q L+ E L + K L +
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH--------- 1369
Query: 139 LQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATH 198
Q + L+ + RLR Q+ + ++ E QQ Q+ + QLR D +
Sbjct: 1370 -QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE----------QQLRQDRDRK--- 1415
Query: 199 LARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQ 258
R EE Q + R R R+ EQ+ E + + L E Q
Sbjct: 1416 -FREEE----------------QQLSRQERDRKFREEEQQVRRQERERK----FLEEEQQ 1454
Query: 259 VAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSA 318
+ Q +R + +Q ++++ ++Q RQ D +++ Q + S
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER---DRKFREQELRSQ 1511
Query: 319 QAVLELEEQEREL-CAVFQRGLGSFNQQLANEQKAQQ 354
+ + E+E++L QR QQL +++ QQ
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Score = 35.8 bits (81), Expect = 0.065
Identities = 64/318 (20%), Positives = 126/318 (39%), Gaps = 50/318 (15%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E RR R++E Q + R + + + + +RRE E +E Q Q +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQL--------RRKQEEERREQQEERREQQERREQ-QEERR 335
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
Q L +E+ +R Q ++ QE ++QQL+ +E + + L
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE-----QQLRREQQLRREQQLR 390
Query: 137 ASLQYFSGEDLDRDTRLRMQQGQFR-YNLERQQQ---EQQQAKVDENYTDALSNQ-LRLA 191
Q + L R+ +LR +Q R L R+QQ EQ++ + ++ + Q L+
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Query: 192 MDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSD 251
+ + L R EE+ R + + Q R + E +RE+ L E + + +
Sbjct: 451 QEERRDWLKREEETERH---------EQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 252 LLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWK 311
+ + EQ+ R+EQ ++R +++ Q + + +
Sbjct: 502 RREQQ--------------------LRREQEE--RREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 312 SQTMSSAQAVLELEEQER 329
+ + +L+ EE++R
Sbjct: 540 REQEERREQLLKREEEKR 557
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/208 (22%), Positives = 85/208 (40%), Gaps = 7/208 (3%)
Query: 147 LDRDTRLRMQQGQFRYNLERQQQEQQQAKV-DENYTDALSNQLRLAMDAQATHLARLEES 205
LD + R R + RQ+++Q++ + D + + R Q LA EE
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE- 153
Query: 206 CRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTEN-PQVAQHPM 264
++ + ++ + + RQR E Q ++ E Q QS TE P Q +
Sbjct: 154 -QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ--L 210
Query: 265 APYRVLPYCWKGMTPEQQAAIRKEQEV-QRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLE 323
+L KG +QQ ++ V Q +++ R+ E L E + Q E
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 324 LEEQERELCAVFQRGLGSFNQQLANEQK 351
L+E+E +L + ++ L Q+ +Q+
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQ 298
Score = 34.7 bits (78), Expect = 0.15
Identities = 54/321 (16%), Positives = 116/321 (36%), Gaps = 31/321 (9%)
Query: 9 DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
+ +E A E + K + F ++ ++ L + + K+++ ER
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 69 SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
+ ++ +L KEE + ++ +E +E+++QL+ L Q
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE--------- 292
Query: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQL 188
+ + L R+ +LR +Q + R + +++EQQ+ + E + QL
Sbjct: 293 -----------EEQQQQRLRREQQLRRKQEEERREQQEERREQQERR--EQQEERREQQL 339
Query: 189 RLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQS 248
R + + R E+ + Q + +R E+Q ++ L Q
Sbjct: 340 RREQEERREQQLRREQE---------EERREQQLRREQEEERREQQLRREQQLRREQQLR 390
Query: 249 TSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDT 308
L Q+ + + + EQQ +E+E K + R+ ++
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Query: 309 EWKSQTMSSAQAVLELEEQER 329
+ + + + E EQER
Sbjct: 451 QEERRDWLKREEETERHEQER 471
Score = 34.7 bits (78), Expect = 0.15
Identities = 71/349 (20%), Positives = 133/349 (38%), Gaps = 79/349 (22%)
Query: 9 DTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGT 68
+ +E E R R ++ Q R + ++ + Q L + R+R+E +E Y
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE-----RERQYRK 962
Query: 69 SQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLS 128
+ Q+L +E R RQ +K ++RE+ ++L+ E L +
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREK--KYREE-EELQQEEEQLLRE------------- 1006
Query: 129 YSNTYPGPASLQYFSGEDLDRDTRLRMQ-QGQFRYNLERQQQEQQQAKVDENYTDALSNQ 187
+R+ R R + + Q+R E QQ+E+Q + + +
Sbjct: 1007 -------------------EREKRRRQEWERQYRKKDELQQEEEQLLREER--------E 1039
Query: 188 LRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQ 247
R + + + R EE + + + + RQ ERQ ++ L + + Q
Sbjct: 1040 KRRLQERERQY--REEEELQQEEEQLLGEERETRR-----RQELERQYRKEEELQQEEEQ 1092
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR-QAEKTL 306
LL E P+ K E++ R+E+E+Q+ ++Q R + EK
Sbjct: 1093 ----LLREEPE----------------KRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 307 DTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQD 355
E + Q + E E+ RE +R +Q E++ QQ+
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLRE--EPEKRRRQELERQYREEEELQQE 1179
Score = 33.5 bits (75), Expect = 0.32
Identities = 54/282 (19%), Positives = 108/282 (38%), Gaps = 52/282 (18%)
Query: 51 DRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
+++RR+ ER KE +Q LE+EE + R+ A+++QE + Q+ + R
Sbjct: 818 EQRRRQRREREKE-------------LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 111 FSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQE 170
Q W+ L+ + + R + L+ Q ++
Sbjct: 865 SQEQRRDQKWRW-----------------------QLEEERKRRRHTLYAKPALQEQLRK 901
Query: 171 QQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQR 230
+QQ +E + L + R Q EE + Q + +R
Sbjct: 902 EQQLLQEEE--EELQREEREKRRRQEQERQYREEE--------QLQQEEEQLLREEREKR 951
Query: 231 CERQREQKANLAEIQHQSTSDLLTENPQVA--QHPMAPYRVLPYCWKGMTPEQQAAIRKE 288
++RE++ + Q LL E P+ Q YR + + E++ +R+E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE----EELQQEEEQLLREE 1007
Query: 289 QEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERE 330
+E +R ++ + +K + + Q + + L+E+ER+
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Score = 33.5 bits (75), Expect = 0.32
Identities = 63/321 (19%), Positives = 128/321 (39%), Gaps = 32/321 (9%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E RR +E ERQ R + + + + L + +++RR+ ER Q +
Sbjct: 1069 ETRRRQELERQYR----KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE--- 1121
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGP 136
Q+L +E R RQ ++ ++RE+++ + + +P + + Y
Sbjct: 1122 -QLLREEREKRRRQELER--QYREEEEVQQEEEQLLREEPEKRRRQ-----ELERQYREE 1173
Query: 137 ASLQYFSGEDL--DRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQL-----R 189
LQ + L +++ R + ++ Q+R E Q+Q+++Q DE+ L Q
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233
Query: 190 LAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQST 249
D + R E R + + Q ++ ER REQ+ + Q
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR----RWQQR 1289
Query: 250 SDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR--QAEKTLD 307
E Q+ + + + E++ +R+E+E +R +++ R + E+ L
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRR----DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLL 1345
Query: 308 TEWKSQTMSSAQAVLELEEQE 328
E + Q + + + E+E
Sbjct: 1346 QEREEQPLRRQERDRKFREEE 1366
Score = 28.9 bits (63), Expect = 8.0
Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 11/94 (11%)
Query: 17 EARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVV 76
E ++ R +ER +F + Q L +Q DRK RE Q++ +
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-----------EEQLRQERE 1808
Query: 77 VQMLEKEEADRTRQLAKKVQEFREQKQQLKNGRE 110
Q L ++ D + ++ + EQ+Q+L+ R+
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 8e-05
Identities = 58/289 (20%), Positives = 117/289 (40%), Gaps = 30/289 (10%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + Q+ K+REA + + +Q++ L K+ AD +L +++ + KQ
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 104 QLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYN 163
+L+ + + + + T + G + ED + + + ++ Q N
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETV----SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIN 1275
Query: 164 LERQQQEQQQAKVDE-----NYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANAN 218
Q+ + Q + E + D L +QL A + L+ + A A+
Sbjct: 1276 DLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
Query: 219 KAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMT 278
A+Q+ R C+ REQ E + + + N +VAQ W+ T
Sbjct: 1336 ----ALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQ------------WR--T 1377
Query: 279 PEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQ 327
+ AI++ +E++ +KK + A++ D E + +++ A LE +Q
Sbjct: 1378 KYETDAIQRTEELEEAKK---KLAQRLQDAEEHVEAVNAKCASLEKTKQ 1423
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 8e-05
Identities = 63/293 (21%), Positives = 118/293 (40%), Gaps = 38/293 (12%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + Q+ K+REA + S +Q++ L K+ AD +L +++ + KQ
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQ 1219
Query: 104 QLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYN 163
+L+ + + + + T + ED + + + ++ Q N
Sbjct: 1220 KLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTL----EDQLSEIKTKEEEQQRLIN 1275
Query: 164 LERQQQEQQQAKVDE-----NYTDALSNQL---RLAMDAQATHLAR-LEESCRAAMMCAM 214
Q+ + + E + DA+ +QL + A Q L R LEE +A A
Sbjct: 1276 ELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAH 1335
Query: 215 ANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCW 274
A +Q+ R C+ REQ E + + + N +VAQ W
Sbjct: 1336 A--------LQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQ------------W 1375
Query: 275 KGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQ 327
+ T + AI++ +E++ +KK + A++ D E + ++S A LE +Q
Sbjct: 1376 R--TKYETDAIQRTEELEEAKK---KLAQRLQDAEEHVEAVNSKCASLEKTKQ 1423
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/369 (21%), Positives = 146/369 (39%), Gaps = 76/369 (20%)
Query: 70 QVQYDVVVQMLEKE--EADRTRQLAKKVQEFREQKQQLKNG-------REFSLWDPGQVW 120
Q QY V+ +K + + +QLA +Q+F+ K ++ + R S+ D G +W
Sbjct: 627 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIW 686
Query: 121 KGLPTY-------------LSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQ 167
+ PT L T PGPA Q + L++ +++Q + + R
Sbjct: 687 ELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL---QQLEKAKAAKLEQERREAEM-RA 742
Query: 168 QQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAG 227
++E+++ K E LR + + EE R A+ + + A++
Sbjct: 743 KREEEERKRQEELRRQQEEILRRQQEEERKRREE-EELARRKQEEALRRQREQEIALRRQ 801
Query: 228 RQRCERQREQKA-------NLAEIQHQSTSDLLTENPQVA----------QHPMAPYRV- 269
R+ ERQ++++A E + + +LL + + A Q + R+
Sbjct: 802 REEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLR 861
Query: 270 LPYCWKGMTPEQQAAIRKEQEVQRSK-----KQAHRQAEKTLDTEWKSQ----------- 313
+ + E++ RKE EVQR K +Q ++A + L + + Q
Sbjct: 862 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
Query: 314 --------TMSSAQAVLEL-------EEQERELCAVFQRGLGSFNQQLANEQKAQQDYLN 358
T +QA L L EE+ER+L +R + L +Q+ QQ L+
Sbjct: 922 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLS 981
Query: 359 SVIYTNQPT 367
++P+
Sbjct: 982 GWGNVSKPS 990
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/372 (18%), Positives = 145/372 (38%), Gaps = 71/372 (19%)
Query: 11 KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
+E E R RE+E + R +R + + Q +RKRRE A R +E A
Sbjct: 733 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 789
Query: 68 TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
+ Q + + E+EE + + ++++E R ++++ + E L
Sbjct: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL---------------L 834
Query: 128 SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQ 187
+ + + + RLRM++ R E +++++++ +V +
Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR------QKE 888
Query: 188 LRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQ 247
L Q L RL++ + + M + + Q+ C Q + +LAEIQ
Sbjct: 889 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC--QSQATLSLAEIQK- 945
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLD 307
L E + + + EQ+ R+++E+ ++ +Q +Q ++ L
Sbjct: 946 -----LEEERE----------------RQLREEQR---RQQRELMKALQQQQQQQQQKL- 980
Query: 308 TEW--KSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQ 365
+ W S+ + +++LE++++E +Q+ +Q+ QQ + N
Sbjct: 981 SGWGNVSKPSGTTKSLLEIQQEEA--------------RQMQKQQQQQQQHQQPNRARNN 1026
Query: 366 PTAQYHQQFNTS 377
+ H S
Sbjct: 1027 THSNLHTSIGNS 1038
Score = 29.6 bits (65), Expect = 4.7
Identities = 35/183 (19%), Positives = 72/183 (39%), Gaps = 21/183 (11%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
++ + ++ +E +R +E RQ + + + + Q Q+ K ++ ++
Sbjct: 869 LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 926
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+ Q Q + + ++K E +R RQL +E R Q+++L + Q G
Sbjct: 927 SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 983
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
S T + L +QQ + R ++QQQ+QQ + + +
Sbjct: 984 GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT 1027
Query: 184 LSN 186
SN
Sbjct: 1028 HSN 1030
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/369 (21%), Positives = 146/369 (39%), Gaps = 76/369 (20%)
Query: 70 QVQYDVVVQMLEKE--EADRTRQLAKKVQEFREQKQQLKNG-------REFSLWDPGQVW 120
Q QY V+ +K + + +QLA +Q+F+ K ++ + R S+ D G +W
Sbjct: 654 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIW 713
Query: 121 KGLPTY-------------LSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQ 167
+ PT L T PGPA Q + L++ +++Q + + R
Sbjct: 714 ELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL---QQLEKAKAAKLEQERREAEM-RA 769
Query: 168 QQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAG 227
++E+++ K E LR + + EE R A+ + + A++
Sbjct: 770 KREEEERKRQEELRRQQEEILRRQQEEERKRREE-EELARRKQEEALRRQREQEIALRRQ 828
Query: 228 RQRCERQREQKA-------NLAEIQHQSTSDLLTENPQVA----------QHPMAPYRV- 269
R+ ERQ++++A E + + +LL + + A Q + R+
Sbjct: 829 REEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLR 888
Query: 270 LPYCWKGMTPEQQAAIRKEQEVQRSK-----KQAHRQAEKTLDTEWKSQ----------- 313
+ + E++ RKE EVQR K +Q ++A + L + + Q
Sbjct: 889 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
Query: 314 --------TMSSAQAVLEL-------EEQERELCAVFQRGLGSFNQQLANEQKAQQDYLN 358
T +QA L L EE+ER+L +R + L +Q+ QQ L+
Sbjct: 949 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLS 1008
Query: 359 SVIYTNQPT 367
++P+
Sbjct: 1009 GWGNVSKPS 1017
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/372 (18%), Positives = 145/372 (38%), Gaps = 71/372 (19%)
Query: 11 KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
+E E R RE+E + R +R + + Q +RKRRE A R +E A
Sbjct: 760 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 816
Query: 68 TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
+ Q + + E+EE + + ++++E R ++++ + E L
Sbjct: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL---------------L 861
Query: 128 SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQ 187
+ + + + RLRM++ R E +++++++ +V +
Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR------QKE 915
Query: 188 LRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQ 247
L Q L RL++ + + M + + Q+ C Q + +LAEIQ
Sbjct: 916 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC--QSQATLSLAEIQK- 972
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLD 307
L E + + + EQ+ R+++E+ ++ +Q +Q ++ L
Sbjct: 973 -----LEEERE----------------RQLREEQR---RQQRELMKALQQQQQQQQQKL- 1007
Query: 308 TEW--KSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQ 365
+ W S+ + +++LE++++E +Q+ +Q+ QQ + N
Sbjct: 1008 SGWGNVSKPSGTTKSLLEIQQEEA--------------RQMQKQQQQQQQHQQPNRARNN 1053
Query: 366 PTAQYHQQFNTS 377
+ H S
Sbjct: 1054 THSNLHTSIGNS 1065
Score = 29.6 bits (65), Expect = 4.7
Identities = 35/183 (19%), Positives = 72/183 (39%), Gaps = 21/183 (11%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
++ + ++ +E +R +E RQ + + + + Q Q+ K ++ ++
Sbjct: 896 LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 953
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+ Q Q + + ++K E +R RQL +E R Q+++L + Q G
Sbjct: 954 SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 1010
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
S T + L +QQ + R ++QQQ+QQ + + +
Sbjct: 1011 GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT 1054
Query: 184 LSN 186
SN
Sbjct: 1055 HSN 1057
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/369 (21%), Positives = 146/369 (39%), Gaps = 76/369 (20%)
Query: 70 QVQYDVVVQMLEKE--EADRTRQLAKKVQEFREQKQQLKNG-------REFSLWDPGQVW 120
Q QY V+ +K + + +QLA +Q+F+ K ++ + R S+ D G +W
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIW 692
Query: 121 KGLPTY-------------LSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQ 167
+ PT L T PGPA Q + L++ +++Q + + R
Sbjct: 693 ELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL---QQLEKAKAAKLEQERREAEM-RA 748
Query: 168 QQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAG 227
++E+++ K E LR + + EE R A+ + + A++
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREE-EELARRKQEEALRRQREQEIALRRQ 807
Query: 228 RQRCERQREQKA-------NLAEIQHQSTSDLLTENPQVA----------QHPMAPYRV- 269
R+ ERQ++++A E + + +LL + + A Q + R+
Sbjct: 808 REEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLR 867
Query: 270 LPYCWKGMTPEQQAAIRKEQEVQRSK-----KQAHRQAEKTLDTEWKSQ----------- 313
+ + E++ RKE EVQR K +Q ++A + L + + Q
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 314 --------TMSSAQAVLEL-------EEQERELCAVFQRGLGSFNQQLANEQKAQQDYLN 358
T +QA L L EE+ER+L +R + L +Q+ QQ L+
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLS 987
Query: 359 SVIYTNQPT 367
++P+
Sbjct: 988 GWGNVSKPS 996
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/372 (18%), Positives = 145/372 (38%), Gaps = 71/372 (19%)
Query: 11 KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
+E E R RE+E + R +R + + Q +RKRRE A R +E A
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 795
Query: 68 TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
+ Q + + E+EE + + ++++E R ++++ + E L
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL---------------L 840
Query: 128 SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQ 187
+ + + + RLRM++ R E +++++++ +V +
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR------QKE 894
Query: 188 LRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQ 247
L Q L RL++ + + M + + Q+ C Q + +LAEIQ
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC--QSQATLSLAEIQK- 951
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLD 307
L E + + + EQ+ R+++E+ ++ +Q +Q ++ L
Sbjct: 952 -----LEEERE----------------RQLREEQR---RQQRELMKALQQQQQQQQQKL- 986
Query: 308 TEW--KSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQ 365
+ W S+ + +++LE++++E +Q+ +Q+ QQ + N
Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEEA--------------RQMQKQQQQQQQHQQPNRARNN 1032
Query: 366 PTAQYHQQFNTS 377
+ H S
Sbjct: 1033 THSNLHTSIGNS 1044
Score = 29.6 bits (65), Expect = 4.7
Identities = 35/183 (19%), Positives = 72/183 (39%), Gaps = 21/183 (11%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
++ + ++ +E +R +E RQ + + + + Q Q+ K ++ ++
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+ Q Q + + ++K E +R RQL +E R Q+++L + Q G
Sbjct: 933 SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 989
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
S T + L +QQ + R ++QQQ+QQ + + +
Sbjct: 990 GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT 1033
Query: 184 LSN 186
SN
Sbjct: 1034 HSN 1036
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/369 (21%), Positives = 146/369 (39%), Gaps = 76/369 (20%)
Query: 70 QVQYDVVVQMLEKE--EADRTRQLAKKVQEFREQKQQLKNG-------REFSLWDPGQVW 120
Q QY V+ +K + + +QLA +Q+F+ K ++ + R S+ D G +W
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIW 692
Query: 121 KGLPTY-------------LSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQ 167
+ PT L T PGPA Q + L++ +++Q + + R
Sbjct: 693 ELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQL---QQLEKAKAAKLEQERREAEM-RA 748
Query: 168 QQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAG 227
++E+++ K E LR + + EE R A+ + + A++
Sbjct: 749 KREEEERKRQEELRRQQEEILRRQQEEERKRREE-EELARRKQEEALRRQREQEIALRRQ 807
Query: 228 RQRCERQREQKA-------NLAEIQHQSTSDLLTENPQVA----------QHPMAPYRV- 269
R+ ERQ++++A E + + +LL + + A Q + R+
Sbjct: 808 REEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLR 867
Query: 270 LPYCWKGMTPEQQAAIRKEQEVQRSK-----KQAHRQAEKTLDTEWKSQ----------- 313
+ + E++ RKE EVQR K +Q ++A + L + + Q
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Query: 314 --------TMSSAQAVLEL-------EEQERELCAVFQRGLGSFNQQLANEQKAQQDYLN 358
T +QA L L EE+ER+L +R + L +Q+ QQ L+
Sbjct: 928 TWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLS 987
Query: 359 SVIYTNQPT 367
++P+
Sbjct: 988 GWGNVSKPS 996
Score = 41.6 bits (96), Expect = 0.001
Identities = 68/372 (18%), Positives = 145/372 (38%), Gaps = 71/372 (19%)
Query: 11 KEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRRE---AAERSKEAAYG 67
+E E R RE+E + R +R + + Q +RKRRE A R +E A
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEI---LRRQQEEERKRREEEELARRKQEEALR 795
Query: 68 TSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
+ Q + + E+EE + + ++++E R ++++ + E L
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL---------------L 840
Query: 128 SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQ 187
+ + + + RLRM++ R E +++++++ +V +
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQR------QKE 894
Query: 188 LRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQ 247
L Q L RL++ + + M + + Q+ C Q + +LAEIQ
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC--QSQATLSLAEIQK- 951
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLD 307
L E + + + EQ+ R+++E+ ++ +Q +Q ++ L
Sbjct: 952 -----LEEERE----------------RQLREEQR---RQQRELMKALQQQQQQQQQKL- 986
Query: 308 TEW--KSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQ 365
+ W S+ + +++LE++++E +Q+ +Q+ QQ + N
Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEEA--------------RQMQKQQQQQQQHQQPNRARNN 1032
Query: 366 PTAQYHQQFNTS 377
+ H S
Sbjct: 1033 THSNLHTSIGNS 1044
Score = 29.6 bits (65), Expect = 4.7
Identities = 35/183 (19%), Positives = 72/183 (39%), Gaps = 21/183 (11%)
Query: 4 IKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKE 63
++ + ++ +E +R +E RQ + + + + Q Q+ K ++ ++
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQ--QQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQ 932
Query: 64 AAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGL 123
+ Q Q + + ++K E +R RQL +E R Q+++L + Q G
Sbjct: 933 SNTTACQSQATLSLAEIQKLEEERERQLR---EEQRRQQRELMKALQQQQQQQQQKLSGW 989
Query: 124 PTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDA 183
S T + L +QQ + R ++QQQ+QQ + + +
Sbjct: 990 GNVSKPSGT----------------TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT 1033
Query: 184 LSN 186
SN
Sbjct: 1034 HSN 1036
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 44.7 bits (104), Expect = 1e-04
Identities = 74/353 (20%), Positives = 140/353 (39%), Gaps = 49/353 (13%)
Query: 23 EKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQ---VQYDVVVQM 79
E ++QN V + V +Q + ++KE G + ++ D
Sbjct: 775 EAQQQNSVIEVTKGQLEVQIQTVT-------------QAKEVIQGEVRCLKLELDTERSQ 821
Query: 80 LEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASL 139
E+E RQLA+ QE + +Q K E + + W+ ++ + +L
Sbjct: 822 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSW----HQQELAKAL 877
Query: 140 QYFSGEDLDRDTRLRMQQG-----QFRYNLERQQQE----QQQAKVDENYTDALSNQLRL 190
+ E ++ + RL+ QQ Q + ER Q E Q Q + ++ L L+
Sbjct: 878 ESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQT 937
Query: 191 AMDA--QATHLARLEESCRAAMMCAMANANKAQAAVQ-AGRQRCERQREQKANLAEIQHQ 247
+ + L RL + + + Q +Q A R+ E R+ + +LA +Q +
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Query: 248 STSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRS--KKQAHRQAEKT 305
S+S + Q M + + + + + EQEVQ + Q + + +K
Sbjct: 998 SSS--------LLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE 1049
Query: 306 LDTEWKSQTMS---SAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQD 355
L+ E S T+S Q +L L+E + ++ Q+ L + Q + Q Q++
Sbjct: 1050 LEREKASLTLSLMEKEQRLLVLQEAD----SIRQQELSALRQDMQEAQGEQKE 1098
Score = 35.8 bits (81), Expect = 0.065
Identities = 70/269 (26%), Positives = 107/269 (39%), Gaps = 53/269 (19%)
Query: 72 QYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSN 131
Q + +Q L ++ + + L+++ QE +QQL+ RE G++ +
Sbjct: 1754 QLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE-----QGELKE---------- 1798
Query: 132 TYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDE----NYTDALSNQ 187
SLQ LD R Q+ Q LE QQEQQQA+ E DAL
Sbjct: 1799 -----QSLQ----SQLDEAQRALAQRDQ---ELEALQQEQQQAQGQEERVKEKADALQGA 1846
Query: 188 LRLA-MDAQATH--LARLEESCRAAMMCAMANANKAQAAVQA-GRQRCERQREQKANLAE 243
L A M + H L +E R + QA + G R E + ++KA LA
Sbjct: 1847 LEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLA- 1905
Query: 244 IQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIR---KEQEVQRSKKQAHR 300
+Q Q + AQ R L W + QA ++ +E E R++ Q+ R
Sbjct: 1906 LQQQCA--------EQAQEHEVETRALQDSWL----QAQAVLKERDQELEALRAESQSSR 1953
Query: 301 QAEKT--LDTEWKSQTMSSAQAVLELEEQ 327
E+ E + + A A L+ +EQ
Sbjct: 1954 HQEEAARARAEALQEALGKAHAALQGKEQ 1982
Score = 33.9 bits (76), Expect = 0.25
Identities = 50/260 (19%), Positives = 103/260 (39%), Gaps = 31/260 (11%)
Query: 148 DRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESC- 206
++ +L + + + LER Q +Q + E + L L++ ++ L+E
Sbjct: 2136 EQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAM 2195
Query: 207 --RAAMMCAMANANKAQAAVQAGRQRCERQREQK---ANLAEIQHQSTSDLLTENPQVAQ 261
+A+++ + + Q ++ R+ E++R + AE+ + + +
Sbjct: 2196 FLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVE 2255
Query: 262 HPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHR-QAEKTLDT------EWKSQT 314
+P + W+ Q A+ + E+ RS+ Q H Q TL+ + K +
Sbjct: 2256 AEPSPDGMEKQSWRQRLEHLQQAVAR-LEIDRSRLQRHNVQLRSTLEQVERERRKLKREA 2314
Query: 315 MSSAQA-VLELEE----------------QERELCAVFQRGLGSFNQQLANEQKAQQDYL 357
M +AQA LE+ + + + A Q+ + QL E+K +QDY+
Sbjct: 2315 MRAAQAGSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLTLERKQKQDYI 2374
Query: 358 NSVIYTNQPTAQYHQQFNTS 377
T++ A H + S
Sbjct: 2375 TRSAQTSRELAGLHHSLSHS 2394
Score = 28.9 bits (63), Expect = 8.0
Identities = 82/341 (24%), Positives = 130/341 (38%), Gaps = 56/341 (16%)
Query: 37 VMGVDVQALNNQV-GDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKE-----EADRTRQ 90
V+ ++Q + +V R++ E +R KE + T ++ ML+KE E RTRQ
Sbjct: 1620 VLARELQERDQEVKSQREQIEELQRQKE--HLTQDLERRDQELMLQKERIQVLEDQRTRQ 1677
Query: 91 LAKKVQEFREQKQQLKN-GREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDL-- 147
++ + K L+ GRE L Q+ + + GP+ Q S E +
Sbjct: 1678 TKILEEDLEQIKLSLRERGRE--LTTQRQLMQ------ERAEEGKGPSKAQRGSLEHMKL 1729
Query: 148 ---DRDTRLRMQQGQFRYNLERQQQEQQQA-----KVDENYTDALSNQLRLAMDAQATHL 199
D++ + QQ E + Q +QQ KV E T L +Q + L
Sbjct: 1730 ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGE--TSLLLSQREQEIVVLQQQL 1787
Query: 200 ARLEESCRAAMMCAMANANKAQAAVQAGRQRCER-QREQKANLAEIQHQSTSDLLTENPQ 258
E + ++AQ A+ Q E Q+EQ+ Q Q + + E
Sbjct: 1788 QEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ------QAQGQEERVKEKAD 1841
Query: 259 VAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQ--EVQRSKKQAHRQAEKTLDTEWKSQTMS 316
Q + EQ KE+ E+Q K+QA R E+ + Q +
Sbjct: 1842 ALQGAL---------------EQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALE 1886
Query: 317 SAQAVLELE--EQERELCAVFQRGLGSFNQQLANEQKAQQD 355
L E EQE+ L A+ Q+ Q+ E +A QD
Sbjct: 1887 EVLGDLRAESREQEKALLAL-QQQCAEQAQEHEVETRALQD 1926
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 44.3 bits (103), Expect = 2e-04
Identities = 77/349 (22%), Positives = 141/349 (40%), Gaps = 52/349 (14%)
Query: 44 ALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQ 103
A + Q+ K+REA + + +Q++ L K+ AD +L +++ + KQ
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 104 QL-KNGREFSLW------DPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQ 156
+L K EF L + Q+ K T + E+ R
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTS 1275
Query: 157 QGQFRYNLERQQQEQQQAKVDENYTDALSNQL---RLAMDAQATHLAR-LEESCRAAMMC 212
Q R L+ + E + ++DE +AL +QL +L Q L R LEE +A
Sbjct: 1276 Q---RAKLQTENGELSR-QLDEK--EALISQLTRGKLTYTQQLEDLKRQLEEEVKAK--- 1326
Query: 213 AMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPY 272
N A+Q+ R C+ REQ E + + L N +VAQ
Sbjct: 1327 -----NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ----------- 1370
Query: 273 CWKGMTPEQQAAIRKEQEVQRSKK---QAHRQAEKTLDT---------EWKSQTMSSAQA 320
W+ T + AI++ +E++ +KK Q ++AE+ ++ + K + + +
Sbjct: 1371 -WR--TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIED 1427
Query: 321 VLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQ 369
++ E+ A + +F++ LA E K + + S + ++Q A+
Sbjct: 1428 LMVDVERSNAAAAALDKKQRNFDKILA-EWKQKYEESQSELESSQKEAR 1475
>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
Length = 968
Score = 44.3 bits (103), Expect = 2e-04
Identities = 72/337 (21%), Positives = 138/337 (40%), Gaps = 63/337 (18%)
Query: 17 EARRNR-EKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQV-QYD 74
EARR R E++R F + ++M +V+ ++ ++R+E+ ++ E Q+ D
Sbjct: 638 EARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRD 697
Query: 75 VVVQMLEKEE-------ADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYL 127
V + E E D R++ K +E +KQ+L RE +LW+
Sbjct: 698 FVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWE------------ 745
Query: 128 SYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQ---QEQQQAKVDENYTDAL 184
L +L QQ + +Y L+R + + +++ + + Y +
Sbjct: 746 --------------MEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRM 791
Query: 185 SNQLRLAMDAQATHLARLEES---CRAAMMCAMANANKAQAAVQAGRQRCERQREQKANL 241
QL++ + L +++ S R AM + N +A + +R++ ++ +
Sbjct: 792 IEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAE------QREKIKQFSQ 845
Query: 242 AEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRK-----EQEVQRSK- 295
E + Q + L Q +H +L C M+ QQ K E E Q+ K
Sbjct: 846 QEEKRQKSERL----QQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKA 901
Query: 296 -KQAHRQAEKTLDTEWKSQTMSSAQAVLE-LEEQERE 330
++H Q K EW+ + +A+ E L +++RE
Sbjct: 902 LDESHNQNLK----EWRDKLRPRKKALEEDLNQKKRE 934
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 43.1 bits (100), Expect = 4e-04
Identities = 76/326 (23%), Positives = 130/326 (39%), Gaps = 31/326 (9%)
Query: 53 KRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTR-------QLAKKVQEFR---EQK 102
K +A +S+E A + + + +L + EADR R QL K +Q+ R E+
Sbjct: 642 KELQAERQSQEVAGRHRDRELEKQLAVL-RVEADRGRELEEQNLQLQKTLQQLRQDCEEA 700
Query: 103 QQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQ--- 159
+ K E GQ + T L + + E ++TR + G+
Sbjct: 701 SKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVE 760
Query: 160 --FRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANA 217
R L+R + E+QQ + N + L A A ARLEE+ R
Sbjct: 761 ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALE---ARLEEAQRGLARLGQEQQ 817
Query: 218 NKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGM 277
+A + G+QR E R KA L E + + N ++ + + L +
Sbjct: 818 TLNRALEEEGKQR-EVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQL 876
Query: 278 TPEQQAAIRKEQEVQRSKKQAHRQAEKTL--------DTEWKSQTMSSAQAVLELEEQER 329
++ A R+ + QR K +AEKT + + Q + ++QA + ++
Sbjct: 877 EDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDK 936
Query: 330 ELCAVFQRGLGSFNQQLANEQKAQQD 355
EL A +GL Q+ N++++Q D
Sbjct: 937 ELLAQRLQGL---EQEAENKKRSQDD 959
Score = 39.3 bits (90), Expect = 0.006
Identities = 69/334 (20%), Positives = 135/334 (40%), Gaps = 40/334 (11%)
Query: 45 LNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLE--KEEADRTRQLAKKVQEFREQK 102
L+ +V R++ E ++ E + + ++LE K EA ++ + + ++ +Q
Sbjct: 375 LDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQG 434
Query: 103 QQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRY 162
+ L++G E + + K + GP + +DL +TR +++
Sbjct: 435 EDLRHGLETQVMELQNKLKHVQ----------GPEPAKEVLLKDL-LETRELLEEV---- 479
Query: 163 NLERQQQEQQQAKVDENYTDALSNQLR---LAMDAQATHLARLEESCRAAMMCAMANANK 219
LE +Q+ ++Q ++ E AL L+ + D + H+ + + + +M +A +
Sbjct: 480 -LEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQ 538
Query: 220 AQAAVQAGRQRCER-----QREQKANLAEIQH-QSTSDLLTENPQVAQHPMAPYRVLPYC 273
A ++A RQ+ QRE + E H QS E+ + + + R+
Sbjct: 539 DHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEE 598
Query: 274 WKGMTPEQQAAIRKEQEVQRSKKQAHRQAE-------------KTLDTEWKSQTMSSAQA 320
+ E+ +++E E R+ RQ E K L E +SQ ++
Sbjct: 599 MEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHR 658
Query: 321 VLELEEQERELCAVFQRGLGSFNQQLANEQKAQQ 354
ELE+Q L RG Q L ++ QQ
Sbjct: 659 DRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQ 692
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.124 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,924,903
Number of Sequences: 37866
Number of extensions: 549936
Number of successful extensions: 4104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 3180
Number of HSP's gapped (non-prelim): 932
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.