Search of human proteins with 71043966

Search of human proteins with 71043966

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71043966 endonuclease/exonuclease/phosphatase family domain
containing 1 [Homo sapiens]
         (569 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71043966 endonuclease/exonuclease/phosphatase family domain c...  1153   0.0  
gi|6453818 kinesin family member 22 [Homo sapiens]                     39   0.013
gi|221136781 S1 RNA binding domain 1 [Homo sapiens]                    34   0.41 
gi|134053959 hypothetical protein LOC79736 [Homo sapiens]              33   0.92 
gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo sa...    32   1.2  
gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo sa...    32   1.2  
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    32   2.0  
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    31   2.7  
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]            31   3.5  
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ...    30   4.6  
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s...    30   4.6  
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled...    30   5.9  
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled...    30   5.9  
gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]                30   5.9  

>gi|71043966 endonuclease/exonuclease/phosphatase family domain
           containing 1 [Homo sapiens]
          Length = 569

 Score = 1153 bits (2983), Expect = 0.0
 Identities = 569/569 (100%), Positives = 569/569 (100%)

Query: 1   MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAV 60
           MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAV
Sbjct: 1   MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAV 60

Query: 61  ARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLA 120
           ARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLA
Sbjct: 61  ARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLA 120

Query: 121 EQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM 180
           EQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM
Sbjct: 121 EQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM 180

Query: 181 DGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQ 240
           DGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQ
Sbjct: 181 DGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQ 240

Query: 241 IISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQ 300
           IISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQ
Sbjct: 241 IISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQ 300

Query: 301 ELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAA 360
           ELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAA
Sbjct: 301 ELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAA 360

Query: 361 GMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNH 420
           GMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNH
Sbjct: 361 GMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNH 420

Query: 421 SDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNIST 480
           SDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNIST
Sbjct: 421 SDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNIST 480

Query: 481 KNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYT 540
           KNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYT
Sbjct: 481 KNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYT 540

Query: 541 EKDWSKKDAPRNGSGVALERSEANIKHER 569
           EKDWSKKDAPRNGSGVALERSEANIKHER
Sbjct: 541 EKDWSKKDAPRNGSGVALERSEANIKHER 569


>gi|6453818 kinesin family member 22 [Homo sapiens]
          Length = 665

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 19/45 (42%), Positives = 27/45 (60%)

Query: 139 INTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGI 183
           +N  +   L S++ +  K A  IV +R  HGPF  VEDL R++GI
Sbjct: 596 LNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGI 640



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 17/51 (33%), Positives = 28/51 (54%)

Query: 42  INTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLE 92
           +N  +  +L +L  +    A+ IV +RE  G F +VEDL  V G+   ++E
Sbjct: 596 LNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQME 646


>gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
          Length = 995

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 15/47 (31%), Positives = 29/47 (61%)

Query: 137 VNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGI 183
           V+IN  +   L  + GL+   A +I+++R ++GPF + E L ++ G+
Sbjct: 708 VDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGL 754



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 18/54 (33%), Positives = 29/54 (53%)

Query: 40  LNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQ 93
           ++IN  +E  L  + G+    A++I+E+RE  G F   E L  V G+G    +Q
Sbjct: 708 VDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQ 761


>gi|134053959 hypothetical protein LOC79736 [Homo sapiens]
          Length = 360

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 14/42 (33%), Positives = 28/42 (66%)

Query: 139 INTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM 180
           +NTA+  +L + R L  + +++IV+ R   GPF+++E L+ +
Sbjct: 77  LNTASTKELEAFRLLRGRRSINIVEHRENFGPFQNLESLMNV 118


>gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo
           sapiens]
          Length = 755

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 1/133 (0%)

Query: 103 KGSSAQHSPSSLRRDLLAEQQPHHLATAVP-LTPRVNINTATPAQLMSVRGLSEKMALSI 161
           K S AQ++ S  ++ LL+E     L   V  L   +        +L+ +    +  A  +
Sbjct: 478 KASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALL 537

Query: 162 VDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSP 221
             ++ +    +++E+ VR        ++R+      +RS+PP  +   G  +T  P  S 
Sbjct: 538 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 597

Query: 222 TSLSLQSEDLDLP 234
           + L L S   +LP
Sbjct: 598 SGLPLGSMGENLP 610


>gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo
           sapiens]
          Length = 367

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 1/133 (0%)

Query: 103 KGSSAQHSPSSLRRDLLAEQQPHHLATAVP-LTPRVNINTATPAQLMSVRGLSEKMALSI 161
           K S AQ++ S  ++ LL+E     L   V  L   +        +L+ +    +  A  +
Sbjct: 71  KASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALL 130

Query: 162 VDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSP 221
             ++ +    +++E+ VR        ++R+      +RS+PP  +   G  +T  P  S 
Sbjct: 131 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 190

Query: 222 TSLSLQSEDLDLP 234
           + L L S   +LP
Sbjct: 191 SGLPLGSMGENLP 203


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 15/150 (10%)

Query: 89  TKLEQVKFEICVSSKG-----SSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTAT 143
           T+L + +   C   +G     S    +P     D L + +  ++  AV    R N     
Sbjct: 259 TELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRM 318

Query: 144 PAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPP 203
              L+S +G+S +M    +D     G +    D+V + G+       I+H   + ++   
Sbjct: 319 LRSLLSAQGVSPQMITVFID-----GYYEEPMDVVALFGLRG-----IQHTPISIKNARV 368

Query: 204 STHTNGGLTFTAKPHPSPTSLSLQSEDLDL 233
           S H    LT T    P      +  EDLD+
Sbjct: 369 SQHYKASLTATFNLFPEAKFAVVLEEDLDI 398


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and
           coiled-coil containing 2 [Homo sapiens]
          Length = 1990

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 19/75 (25%)

Query: 423 GHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKN 482
           GH L +F  + QE     +  I LG                   HH++ AH F  +S K 
Sbjct: 789 GHTLLAFWFSRQEGKLNRQQTIELG-------------------HHILKAHIFKGLSKKV 829

Query: 483 PQGSKSLDNIWISKS 497
              S  L  +WIS S
Sbjct: 830 GVSSSILQGLWISYS 844


>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
          Length = 916

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 50  LMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSG--VGATKLEQVKFEICVSSKGS 105
           L++L G  RA    +        GF + +  AL+S   +   KL QVKF  CV +KG+
Sbjct: 11  LLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGT 68


>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
           sapiens]
          Length = 1726

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 13/63 (20%), Positives = 29/63 (46%)

Query: 204 STHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRL 263
           ++++N G+     P+ +P +  +   +  +  G P+ I S   ++    G ++G P   L
Sbjct: 89  ASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTL 148

Query: 264 ATW 266
             W
Sbjct: 149 GAW 151


>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
           sapiens]
          Length = 1690

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 13/63 (20%), Positives = 29/63 (46%)

Query: 204 STHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRL 263
           ++++N G+     P+ +P +  +   +  +  G P+ I S   ++    G ++G P   L
Sbjct: 89  ASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTL 148

Query: 264 ATW 266
             W
Sbjct: 149 GAW 151


>gi|225543463 tetratricopeptide repeat, ankyrin repeat and
           coiled-coil containing 1 isoform 2 [Homo sapiens]
          Length = 1390

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 19/76 (25%)

Query: 422 DGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTK 481
           +GH L +F  + QE     +  + LG                   HH++ AH F  +S K
Sbjct: 830 NGHALLAFMFSRQEGKLNRQQTMELG-------------------HHILKAHIFKGLSKK 870

Query: 482 NPQGSKSLDNIWISKS 497
               S  L  +WI  S
Sbjct: 871 TGISSSHLQALWIGYS 886


>gi|225543461 tetratricopeptide repeat, ankyrin repeat and
           coiled-coil containing 1 isoform 1 [Homo sapiens]
          Length = 1861

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 19/76 (25%)

Query: 422 DGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTK 481
           +GH L +F  + QE     +  + LG                   HH++ AH F  +S K
Sbjct: 838 NGHALLAFMFSRQEGKLNRQQTMELG-------------------HHILKAHIFKGLSKK 878

Query: 482 NPQGSKSLDNIWISKS 497
               S  L  +WI  S
Sbjct: 879 TGISSSHLQALWIGYS 894


>gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]
          Length = 337

 Score = 30.0 bits (66), Expect = 5.9
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 26/98 (26%)

Query: 438 KGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS 497
           + E  +I++G  G G  +    ILRK+ F   + + T T   +K+ QGS      W ++ 
Sbjct: 20  RSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKS-QGS------WGNRE 72

Query: 498 LKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVL 535
           +  + T               PD +SW     +HC  L
Sbjct: 73  IVIIDT---------------PDMFSW----KDHCEAL 91


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,347,773
Number of Sequences: 37866
Number of extensions: 1107424
Number of successful extensions: 2998
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2983
Number of HSP's gapped (non-prelim): 20
length of query: 569
length of database: 18,247,518
effective HSP length: 108
effective length of query: 461
effective length of database: 14,157,990
effective search space: 6526833390
effective search space used: 6526833390
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.