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Search of human proteins with 70887790
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70887790 DNA-directed DNA polymerase gamma 2 [Homo sapiens]
(485 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70887790 DNA-directed DNA polymerase gamma 2 [Homo sapiens] 997 0.0
gi|22547204 hairless protein isoform a [Homo sapiens] 32 1.3
gi|22547207 hairless protein isoform b [Homo sapiens] 32 1.3
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 31 2.2
gi|38788260 bromodomain PHD finger transcription factor isoform ... 30 3.8
gi|239735575 otoancorin isoform 3 [Homo sapiens] 30 4.9
gi|24638452 otoancorin isoform 2 [Homo sapiens] 30 4.9
gi|77404409 otoancorin isoform 1 [Homo sapiens] 30 4.9
gi|217330589 transforming growth factor, beta receptor associate... 30 4.9
gi|21359865 transforming growth factor, beta receptor associated... 30 4.9
gi|168823443 RAD54-like 2 [Homo sapiens] 30 6.4
gi|122937345 myosin VB [Homo sapiens] 29 8.4
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 29 8.4
gi|12056463 coagulation factor VIII-associated protein [Homo sap... 29 8.4
gi|56090586 coagulation factor VIII-associated (intronic transcr... 29 8.4
gi|56090588 coagulation factor VIII-associated (intronic transcr... 29 8.4
>gi|70887790 DNA-directed DNA polymerase gamma 2 [Homo sapiens]
Length = 485
Score = 997 bits (2578), Expect = 0.0
Identities = 485/485 (100%), Positives = 485/485 (100%)
Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60
MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP
Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60
Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120
GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV
Sbjct: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120
Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180
FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK
Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180
Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240
LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV
Sbjct: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240
Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300
WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI
Sbjct: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300
Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360
ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS
Sbjct: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360
Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420
FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET
Sbjct: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420
Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480
MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS
Sbjct: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480
Query: 481 SAKNV 485
SAKNV
Sbjct: 481 SAKNV 485
>gi|22547204 hairless protein isoform a [Homo sapiens]
Length = 1189
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 36 RSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSR 88
R SP GG ++ + N E PGSG S L +H LSG +L R
Sbjct: 518 RRSPLGGELQQEEDTATNSSSEEGPGSGPDSR--LSTGLAKHLLSGLGDRLCR 568
>gi|22547207 hairless protein isoform b [Homo sapiens]
Length = 1134
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 36 RSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSR 88
R SP GG ++ + N E PGSG S L +H LSG +L R
Sbjct: 518 RRSPLGGELQQEEDTATNSSSEEGPGSGPDSR--LSTGLAKHLLSGLGDRLCR 568
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 31.2 bits (69), Expect = 2.2
Identities = 31/116 (26%), Positives = 41/116 (35%), Gaps = 31/116 (26%)
Query: 31 ELLTERSSPKGG------------HVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHF 78
ELL E+ + GG HVK E G HP+ S E + LL+ C+
Sbjct: 16 ELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVI 75
Query: 79 LSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHK 134
G G LG EL KNLA + + V V L+ +
Sbjct: 76 -------------------GAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ 112
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 30.4 bits (67), Expect = 3.8
Identities = 20/91 (21%), Positives = 33/91 (36%), Gaps = 13/91 (14%)
Query: 19 SGFGGRVDAGQPELLTERSSPKGGHVKSHAEL-------------EGNGEHPEAPGSGEG 65
S +++ Q E P+ G +SH + + NGE E+PG+G+G
Sbjct: 710 SNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKG 769
Query: 66 SEALLEICQRRHFLSGSKQQLSRDSLLSGCH 96
+ I R QL + + H
Sbjct: 770 ASGSTRIITRLRNPDSKLSQLKSQQVAAAAH 800
>gi|239735575 otoancorin isoform 3 [Homo sapiens]
Length = 1060
Score = 30.0 bits (66), Expect = 4.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 128 VDALHHKPGPLLPGDSAFRLVSAETLRE-------ILQDKELSKEQLVAFLENVLKTSGK 180
V A PG + + F+ VS LR +L+DKEL + Q + E +LKT+ +
Sbjct: 419 VQAEDTAPGIVEIQGAFFKEVSLFDLRRQPGFNSTVLKDKELGRSQALFLYELLLKTTRR 478
Query: 181 LRENLLHGALEHYVNC 196
E L G L V C
Sbjct: 479 PEELLSAGQLVKGVTC 494
>gi|24638452 otoancorin isoform 2 [Homo sapiens]
Length = 815
Score = 30.0 bits (66), Expect = 4.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 128 VDALHHKPGPLLPGDSAFRLVSAETLRE-------ILQDKELSKEQLVAFLENVLKTSGK 180
V A PG + + F+ VS LR +L+DKEL + Q + E +LKT+ +
Sbjct: 174 VQAEDTAPGIVEIQGAFFKEVSLFDLRRQPGFNSTVLKDKELGRSQALFLYELLLKTTRR 233
Query: 181 LRENLLHGALEHYVNC 196
E L G L V C
Sbjct: 234 PEELLSAGQLVKGVTC 249
>gi|77404409 otoancorin isoform 1 [Homo sapiens]
Length = 1139
Score = 30.0 bits (66), Expect = 4.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 128 VDALHHKPGPLLPGDSAFRLVSAETLRE-------ILQDKELSKEQLVAFLENVLKTSGK 180
V A PG + + F+ VS LR +L+DKEL + Q + E +LKT+ +
Sbjct: 498 VQAEDTAPGIVEIQGAFFKEVSLFDLRRQPGFNSTVLKDKELGRSQALFLYELLLKTTRR 557
Query: 181 LRENLLHGALEHYVNC 196
E L G L V C
Sbjct: 558 PEELLSAGQLVKGVTC 573
>gi|217330589 transforming growth factor, beta receptor associated
protein 1 [Homo sapiens]
Length = 860
Score = 30.0 bits (66), Expect = 4.9
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 339 NGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQV 398
+G LD L LY T +SFTR HP L + +G ++ +
Sbjct: 375 SGQLDVRELISLYPFLLPTSSSFTRS----------HPPLHEYADLNQLTQGDQEKMAKC 424
Query: 399 CQGLFNELLE-NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTE 445
+ L + L E V GY E + ++L +LY++ D S+L +LVTE
Sbjct: 425 KRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLL-DLLVTE 471
>gi|21359865 transforming growth factor, beta receptor associated
protein 1 [Homo sapiens]
Length = 860
Score = 30.0 bits (66), Expect = 4.9
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 339 NGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQV 398
+G LD L LY T +SFTR HP L + +G ++ +
Sbjct: 375 SGQLDVRELISLYPFLLPTSSSFTRS----------HPPLHEYADLNQLTQGDQEKMAKC 424
Query: 399 CQGLFNELLE-NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTE 445
+ L + L E V GY E + ++L +LY++ D S+L +LVTE
Sbjct: 425 KRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLL-DLLVTE 471
>gi|168823443 RAD54-like 2 [Homo sapiens]
Length = 1467
Score = 29.6 bits (65), Expect = 6.4
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 145 FRLVSAETLREILQDKELSK----EQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLV 200
+RLV+ TL + + D+++SK +++V L +L + K ENLLH + + L
Sbjct: 862 YRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQVSLN 921
Query: 201 NKRLPYGLAQIGVCFHPVFDTKQ 223
K + + Q+ +P TK+
Sbjct: 922 VKGIKESVLQLACLKYPHLITKE 944
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 29.3 bits (64), Expect = 8.4
Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 106 LRKNLAAEWWTSVVVFREQVFPV--DALHHKPGPL---LPGDSAFRLVSAETLREILQDK 160
L KN + + + + FP+ D H P+ PG + +S + R ++
Sbjct: 565 LEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVS 624
Query: 161 ELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPY 206
++ V + +TS L L+ HYV C+ +++LP+
Sbjct: 625 NKEHKKTVG---HQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPF 667
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 29.3 bits (64), Expect = 8.4
Identities = 14/36 (38%), Positives = 17/36 (47%)
Query: 13 VCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHA 48
VC CL+ G G R QP L RS + SH+
Sbjct: 313 VCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHS 348
>gi|12056463 coagulation factor VIII-associated protein [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 8.4
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKN--LAAEWWTSV 118
G+G G EA + + R + K++ R ++ FG LG ELR L W +
Sbjct: 12 GAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQL 71
Query: 119 VVFREQVFPVDALHHKPGPLLPGDSAFRL 147
V R Q AL H PG L A RL
Sbjct: 72 AVARCQ----QALFHGPGEALALTEAARL 96
>gi|56090586 coagulation factor VIII-associated (intronic
transcript) 3 [Homo sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 8.4
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKN--LAAEWWTSV 118
G+G G EA + + R + K++ R ++ FG LG ELR L W +
Sbjct: 12 GAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQL 71
Query: 119 VVFREQVFPVDALHHKPGPLLPGDSAFRL 147
V R Q AL H PG L A RL
Sbjct: 72 AVARCQ----QALFHGPGEALALTEAARL 96
>gi|56090588 coagulation factor VIII-associated (intronic
transcript) 2 [Homo sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 8.4
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKN--LAAEWWTSV 118
G+G G EA + + R + K++ R ++ FG LG ELR L W +
Sbjct: 12 GAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQL 71
Query: 119 VVFREQVFPVDALHHKPGPLLPGDSAFRL 147
V R Q AL H PG L A RL
Sbjct: 72 AVARCQ----QALFHGPGEALALTEAARL 96
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,852,165
Number of Sequences: 37866
Number of extensions: 955997
Number of successful extensions: 2141
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2132
Number of HSP's gapped (non-prelim): 18
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.