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Search of human proteins with 7019439
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019439 potassium inwardly-rectifying channel J14 [Homo
sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 890 0.0
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 890 0.0
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 504 e-143
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 488 e-138
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 482 e-136
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 479 e-135
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 479 e-135
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 463 e-130
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 463 e-130
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 463 e-130
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 358 5e-99
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 351 8e-97
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 347 9e-96
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 343 2e-94
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 312 4e-85
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 304 1e-82
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 304 1e-82
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 304 1e-82
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 298 5e-81
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 289 4e-78
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 289 4e-78
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 289 4e-78
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 289 4e-78
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 289 4e-78
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 263 2e-70
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 256 4e-68
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 256 4e-68
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 256 4e-68
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 197 1e-50
gi|190341107 N-acetyltransferase 12 [Homo sapiens] 37 0.027
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 890 bits (2301), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN 60
MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN
Sbjct: 1 MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN 60
Query: 61 VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA 120
VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA
Sbjct: 61 VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA 120
Query: 121 PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV 180
PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV
Sbjct: 121 PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV 180
Query: 181 VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR 240
VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR
Sbjct: 181 VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR 240
Query: 241 VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV 300
VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV
Sbjct: 241 VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV 300
Query: 301 VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV 360
VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV
Sbjct: 301 VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV 360
Query: 361 CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA 420
CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA
Sbjct: 361 CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA 420
Query: 421 ASPRVLTPTLALTLPP 436
ASPRVLTPTLALTLPP
Sbjct: 421 ASPRVLTPTLALTLPP 436
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 890 bits (2301), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN 60
MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN
Sbjct: 1 MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN 60
Query: 61 VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA 120
VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA
Sbjct: 61 VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAA 120
Query: 121 PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV 180
PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV
Sbjct: 121 PPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFV 180
Query: 181 VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR 240
VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR
Sbjct: 181 VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR 240
Query: 241 VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV 300
VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV
Sbjct: 241 VTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELV 300
Query: 301 VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV 360
VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV
Sbjct: 301 VILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPV 360
Query: 361 CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA 420
CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA
Sbjct: 361 CSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGA 420
Query: 421 ASPRVLTPTLALTLPP 436
ASPRVLTPTLALTLPP
Sbjct: 421 ASPRVLTPTLALTLPP 436
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 504 bits (1298), Expect = e-143
Identities = 239/368 (64%), Positives = 290/368 (78%), Gaps = 9/368 (2%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
R RFVKKDGHCNV+F+N+G +G RYL+D+FTTCVD+RWRWM ++F +F+ SWL FG F
Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
Query: 109 WLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVL 168
WLIA LHGDL A C S V SF AAFLF++ETQT+IGYG R VT+ECP AV VV
Sbjct: 104 WLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF 163
Query: 169 QCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLV 228
Q I GC++DAF++GAVMAKMAKPKKRNETLVFS NAV+A+RD +LCLMWRVGNLR+SHLV
Sbjct: 164 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV 223
Query: 229 EAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELG 288
EAHVRAQLL+ R+T EGEYIPLD D++VGFD G DRIFLVSPITIVHEID SPLY+L
Sbjct: 224 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS 283
Query: 289 RAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRH 348
+ ++ ADFE+VVILEGMVEATAMTTQCRSSYL E+LWGHR+EPVLF+ Y+VDY
Sbjct: 284 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR 343
Query: 349 FHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDET 408
FH+TYEVP TP+CSA++L E+ S++ +FCYENE+AL+ +E+D ++
Sbjct: 344 FHKTYEVPNTPLCSARDLAEKKYILSNA---------NSFCYENEVALTSKEEDDSENGV 394
Query: 409 EEGNGVET 416
E +T
Sbjct: 395 PESTSTDT 402
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 488 bits (1255), Expect = e-138
Identities = 239/367 (65%), Positives = 286/367 (77%), Gaps = 11/367 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
R R RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 41 RCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGI 100
Query: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
FW+IA HGDL A PC V F+AAFLF++ETQT+IGYG+R VTEECP AV
Sbjct: 101 IFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVF 160
Query: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
VV Q I GC++D+F++GA+MAKMA+PKKR +TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
Query: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
Query: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
+ + R +L DFE+VVILEGMVEATAMTTQ RSSYL E+LWGHRFEPVLF+ +QY++
Sbjct: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
Query: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
DY HFH+TYEVP TP CSAK+L E K P S +FCYENELA EEDE
Sbjct: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
Query: 405 DDETEEG 411
D ++G
Sbjct: 392 ADGDQDG 398
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 482 bits (1241), Expect = e-136
Identities = 238/367 (64%), Positives = 284/367 (77%), Gaps = 11/367 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
R R RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L+FS +FLASWLLFG+
Sbjct: 41 RCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGV 100
Query: 107 AFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
FW+IA HGDL A PC V F+AAFLF++ETQT+IGYG+R VTEEC AV
Sbjct: 101 IFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVF 160
Query: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
VV Q I GC++D+F++GA+MAKMA+PKKR TL+FS NAVVALRD +LCLMWRVGNLR+
Sbjct: 161 MVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRK 220
Query: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G DRIFLVSPITI+HEID ASPL
Sbjct: 221 SHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPL 280
Query: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
+ + R +L DFE+VVILEGMVEATAMTTQ RSSYL E+LWGHRFEPVLF+ +QY++
Sbjct: 281 FGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKI 340
Query: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
DY HFH+TYEVP TP CSAK+L E K P S +FCYENELA EEDE
Sbjct: 341 DYSHFHKTYEVPSTPRCSAKDLVEN--------KFLLP-SANSFCYENELAFLSRDEEDE 391
Query: 405 DDETEEG 411
D ++G
Sbjct: 392 ADGDQDG 398
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 479 bits (1234), Expect = e-135
Identities = 237/396 (59%), Positives = 293/396 (73%), Gaps = 26/396 (6%)
Query: 30 GLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWM 89
G RNG A P + +RR RFVKK+G CNV F NL + RY++D+FTTCVD RWR+M
Sbjct: 3 GHSRNGQAHVPRR----KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYM 58
Query: 90 CLLFSCSFLASWLLFGLAFWLIASLHGDL------------------AAPPPPAPCFSHV 131
++FS +FL SWL FGL FW IA HGDL AAP P PC HV
Sbjct: 59 LMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHV 118
Query: 132 ASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKP 191
FL AFLF++ETQT+IGYG R VTEECP AV AVV+Q I GCV+D+F++G +MAKMA+P
Sbjct: 119 NGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
Query: 192 KKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLD 251
KKR +TL+FS +AV+++RD +LCLMWRVGNLR+SH+VEAHVRAQL++P +T EGEY+PLD
Sbjct: 179 KKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLD 238
Query: 252 HQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATA 311
+D++VG+D G DRIFLVSPI IVHEID SPLY +G+ EL DFE+VVILEGMVEATA
Sbjct: 239 QRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATA 298
Query: 312 MTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAE 371
MTTQ RSSYL E+LWGHRFEPV+F+ S Y+VDY FH+TYEV GTP CSA+EL E
Sbjct: 299 MTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE--- 355
Query: 372 QASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDE 407
+ ++ + P +AFCYENELAL +EE+ ++E
Sbjct: 356 -SKITVLPAPPPPPSAFCYENELALMSQEEEEMEEE 390
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 479 bits (1234), Expect = e-135
Identities = 237/396 (59%), Positives = 293/396 (73%), Gaps = 26/396 (6%)
Query: 30 GLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWM 89
G RNG A P + +RR RFVKK+G CNV F NL + RY++D+FTTCVD RWR+M
Sbjct: 3 GHSRNGQAHVPRR----KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYM 58
Query: 90 CLLFSCSFLASWLLFGLAFWLIASLHGDL------------------AAPPPPAPCFSHV 131
++FS +FL SWL FGL FW IA HGDL AAP P PC HV
Sbjct: 59 LMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHV 118
Query: 132 ASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKP 191
FL AFLF++ETQT+IGYG R VTEECP AV AVV+Q I GCV+D+F++G +MAKMA+P
Sbjct: 119 NGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
Query: 192 KKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLD 251
KKR +TL+FS +AV+++RD +LCLMWRVGNLR+SH+VEAHVRAQL++P +T EGEY+PLD
Sbjct: 179 KKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLD 238
Query: 252 HQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATA 311
+D++VG+D G DRIFLVSPI IVHEID SPLY +G+ EL DFE+VVILEGMVEATA
Sbjct: 239 QRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATA 298
Query: 312 MTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAE 371
MTTQ RSSYL E+LWGHRFEPV+F+ S Y+VDY FH+TYEV GTP CSA+EL E
Sbjct: 299 MTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE--- 355
Query: 372 QASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDE 407
+ ++ + P +AFCYENELAL +EE+ ++E
Sbjct: 356 -SKITVLPAPPPPPSAFCYENELALMSQEEEEMEEE 390
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 463 bits (1191), Expect = e-130
Identities = 232/386 (60%), Positives = 288/386 (74%), Gaps = 17/386 (4%)
Query: 34 NGWAPAPVQSPVGRRR--GRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCL 91
NG+ V + RRR RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L
Sbjct: 29 NGFGNGKVHT---RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLL 85
Query: 92 LFSCSFLASWLLFGLAFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIG 149
+FS +FLASWLLFG+ FW+IA HGDL A PC V F+AAFLF+++TQ +I
Sbjct: 86 IFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTIS 145
Query: 150 YGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALR 209
YG+R VTEECP AV VV Q I GC++++F++GA+MAKM +PKKR +TL+FS NAVVALR
Sbjct: 146 YGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALR 205
Query: 210 DHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLV 269
D +LC MWRVGNLR+SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G D FLV
Sbjct: 206 DGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLV 265
Query: 270 SPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGH 329
SPITI+HEID ASPL+ + R +L DFE+V+ILEG+VEATAMTTQ RSSYL E+LWGH
Sbjct: 266 SPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGH 325
Query: 330 RFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFC 389
RFEPVLF++ +QY++DY HFH+TYEVP TP CSAK+L E K P + +FC
Sbjct: 326 RFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRCSAKDLVEN--------KFLLPRA-NSFC 375
Query: 390 YENELALSCCQEEDEDDETEEGNGVE 415
Y+NELA EEDE D ++G E
Sbjct: 376 YKNELAFLSRDEEDEADGDQDGRSRE 401
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 463 bits (1191), Expect = e-130
Identities = 232/386 (60%), Positives = 288/386 (74%), Gaps = 17/386 (4%)
Query: 34 NGWAPAPVQSPVGRRR--GRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCL 91
NG+ V + RRR RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L
Sbjct: 131 NGFGNGKVHT---RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLL 187
Query: 92 LFSCSFLASWLLFGLAFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIG 149
+FS +FLASWLLFG+ FW+IA HGDL A PC V F+AAFLF+++TQ +I
Sbjct: 188 IFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTIS 247
Query: 150 YGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALR 209
YG+R VTEECP AV VV Q I GC++++F++GA+MAKM +PKKR +TL+FS NAVVALR
Sbjct: 248 YGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALR 307
Query: 210 DHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLV 269
D +LC MWRVGNLR+SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G D FLV
Sbjct: 308 DGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLV 367
Query: 270 SPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGH 329
SPITI+HEID ASPL+ + R +L DFE+V+ILEG+VEATAMTTQ RSSYL E+LWGH
Sbjct: 368 SPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGH 427
Query: 330 RFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFC 389
RFEPVLF++ +QY++DY HFH+TYEVP TP CSAK+L E K P + +FC
Sbjct: 428 RFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRCSAKDLVEN--------KFLLPRA-NSFC 477
Query: 390 YENELALSCCQEEDEDDETEEGNGVE 415
Y+NELA EEDE D ++G E
Sbjct: 478 YKNELAFLSRDEEDEADGDQDGRSRE 503
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 463 bits (1191), Expect = e-130
Identities = 232/386 (60%), Positives = 288/386 (74%), Gaps = 17/386 (4%)
Query: 34 NGWAPAPVQSPVGRRR--GRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCL 91
NG+ V + RRR RFVKK+G CN+ F N+ + RYL+D+FTTCVD+RWR+M L
Sbjct: 29 NGFGNGKVHT---RRRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLL 85
Query: 92 LFSCSFLASWLLFGLAFWLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIG 149
+FS +FLASWLLFG+ FW+IA HGDL A PC V F+AAFLF+++TQ +I
Sbjct: 86 IFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTIS 145
Query: 150 YGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALR 209
YG+R VTEECP AV VV Q I GC++++F++GA+MAKM +PKKR +TL+FS NAVVALR
Sbjct: 146 YGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALR 205
Query: 210 DHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLV 269
D +LC MWRVGNLR+SH+VEAHVRAQL++PRVT EGEYIPLD D+DVGFD G D FLV
Sbjct: 206 DGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLV 265
Query: 270 SPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGH 329
SPITI+HEID ASPL+ + R +L DFE+V+ILEG+VEATAMTTQ RSSYL E+LWGH
Sbjct: 266 SPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGH 325
Query: 330 RFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFC 389
RFEPVLF++ +QY++DY HFH+TYEVP TP CSAK+L E K P + +FC
Sbjct: 326 RFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRCSAKDLVEN--------KFLLPRA-NSFC 375
Query: 390 YENELALSCCQEEDEDDETEEGNGVE 415
Y+NELA EEDE D ++G E
Sbjct: 376 YKNELAFLSRDEEDEADGDQDGRSRE 401
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 358 bits (919), Expect = 5e-99
Identities = 187/352 (53%), Positives = 244/352 (69%), Gaps = 4/352 (1%)
Query: 36 WAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSC 95
++P + P R R R+V+KDG CNV+ N+ + RYL+DLFTT VD++WR L F
Sbjct: 8 FSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVR-ETYRYLTDLFTTLVDLQWRLSLLFFVL 66
Query: 96 SFLASWLLFGLAFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVR 153
++ +WL FG +WLIA GDL A PC +++ F+AAFLF++ET+T+IGYG R
Sbjct: 67 AYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHR 126
Query: 154 SVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRL 213
+T++CP + ++LQ I G +++AF+VG + K+++P KR TLVFS +AVV+LRD RL
Sbjct: 127 VITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRL 186
Query: 214 CLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPIT 273
CLM+RVG+LR SH+VEA +RA+L++ R T EGE+IPL D+ VGFD G DR+FLVSP+
Sbjct: 187 CLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLV 246
Query: 274 IVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEP 333
I HEID+ASP +E R L R DFE+VVILEGMVEAT MT Q RSSYL E+LWGHRF
Sbjct: 247 ISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTS 306
Query: 334 VLFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSL 385
VL YEVDY FH T+EVP TP CSA+EL E A + L S P L
Sbjct: 307 VLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAARLDAHLYWSIPSRL 357
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 351 bits (900), Expect = 8e-97
Identities = 182/375 (48%), Positives = 253/375 (67%), Gaps = 9/375 (2%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
R R+++K G CNV N+ + RYLSDLFTT VD++WR+ L+F+ + +WL FG +
Sbjct: 50 RQRYMEKSGKCNVHHGNVQ-ETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
Query: 109 WLIASLHGDL--AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAV 166
WLIA + GDL PC +++ F++AFLF++ET+T+IGYG R +TE+CP + +
Sbjct: 109 WLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILL 168
Query: 167 VLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSH 226
++Q I G +++AF+VG + K+++PKKR ETL+FS NAV+++RD +LCLM+RVG+LR SH
Sbjct: 169 LVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSH 228
Query: 227 LVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYE 286
+VEA +RA+L++ R T EGE+IPL+ D++VGFD G DR+FLVSP+ I HEI+ SP +E
Sbjct: 229 IVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWE 288
Query: 287 LGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDY 346
+ +A+L + +FE+VVILEGMVEAT MT Q RSSY+ E+LWGHRF PVL YEVDY
Sbjct: 289 MSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDY 348
Query: 347 RHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPG-SLTAFCYENELALSCCQEEDED 405
FH TYE TP C AKEL E + L P L C E L E++E+
Sbjct: 349 NTFHDTYET-NTPSCCAKELAEMKREG--RLLQYLPSPPLLGGC--AEAGLDAEAEQNEE 403
Query: 406 DETEEGNGVETEDGA 420
DE + G G+
Sbjct: 404 DEPKGLGGSREARGS 418
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 347 bits (891), Expect = 9e-96
Identities = 175/369 (47%), Positives = 252/369 (68%), Gaps = 9/369 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
R+ R+V+KDG CNV N+ + RYL+D+FTT VD++WR+ L+F + +WL FG+
Sbjct: 51 RKIQRYVRKDGKCNVHHGNVR-ETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGM 109
Query: 107 AFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
+WLIA + GD+ P+ PC +++ F++AFLF++ET+T+IGYG R +T++CP +
Sbjct: 110 IWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGII 169
Query: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
+++Q + G +++AF+VG + K+++PKKR ETLVFS +AV+++RD +LCLM+RVG+LR
Sbjct: 170 LLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRN 229
Query: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
SH+VEA +RA+L++ + T EGE+IPL+ D++VG+ G DR+FLVSP+ I HEI+ SP
Sbjct: 230 SHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPF 289
Query: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
+E+ +A+L + + E+VVILEGMVEAT MT Q RSSY+ E+LWG+RF PVL YEV
Sbjct: 290 WEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEV 349
Query: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
DY FH TYE TP SAKEL E A +A L S L L +EE
Sbjct: 350 DYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKL-----NQHAELETEEEEKN 403
Query: 405 DDETEEGNG 413
+E E NG
Sbjct: 404 LEEQTERNG 412
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 343 bits (880), Expect = 2e-94
Identities = 176/366 (48%), Positives = 242/366 (66%), Gaps = 8/366 (2%)
Query: 6 ALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRR-RGRFVKKDGHCNVRFV 64
ALRR G D + +G GL G P Q V ++ R RFV K+G CNV+
Sbjct: 3 ALRRKFG----DDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHG 58
Query: 65 NLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAPP 122
NLG + +RYLSDLFTT VD++WRW +F ++ +WL +W+IA GDL A
Sbjct: 59 NLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVG 118
Query: 123 PPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVG 182
PC ++V +F +AFLF +ET+ +IGYG R +T++CP + + Q I G ++DAF++G
Sbjct: 119 NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIG 178
Query: 183 AVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVT 242
+ KM++PKKR ETL+FSE+AV+++RD +L LM+RVGNLR SH+V A +R +LL+ R T
Sbjct: 179 CMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQT 238
Query: 243 PEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVI 302
PEGE++PLD ++DVGF G D++FLVSP+TI H ID+ SP Y+L + + FE+VVI
Sbjct: 239 PEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVI 298
Query: 303 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCS 362
LEG+VE T MT Q R+SY E+LWGHRF PV+ ++VDY FH T+EVP TP S
Sbjct: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYS 357
Query: 363 AKELDE 368
KE +E
Sbjct: 358 VKEQEE 363
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 312 bits (799), Expect = 4e-85
Identities = 158/333 (47%), Positives = 227/333 (68%), Gaps = 4/333 (1%)
Query: 38 PAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSF 97
PA + +RR RFV K G+CNV N+ QG R+L D+FTT VD++W L+F+ SF
Sbjct: 21 PAKPRYRARQRRARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSF 79
Query: 98 LASWLLFGLAFWLIASLHGDLAAPPPPA-PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
L SWLLF +A+WLIA HGDLA A PC + + SF +AFLF++E Q +IG+G R VT
Sbjct: 80 LCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVT 139
Query: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
EECP A+ +++Q I G +++A ++G + K A+ +R ETL+FS++AV+ALR RLC M
Sbjct: 140 EECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFM 199
Query: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
RVG+LR+S ++ A + Q+++ +PEGE +PL D+ + G + IFLV+P+ I H
Sbjct: 200 LRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYH 259
Query: 277 EIDSASPLYELGRAEL-ARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL 335
ID+ SPLY+L ++L D E++VILEG+VE T +TTQ R+SYL E+LWG RF P++
Sbjct: 260 VIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIV 319
Query: 336 FQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDE 368
+ +Y VDY F T +VP TP+C+A++LDE
Sbjct: 320 AEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDE 351
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 304 bits (778), Expect = 1e-82
Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%)
Query: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94
G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS
Sbjct: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78
Query: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154
S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R
Sbjct: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214
VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274
LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334
VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372
L + Y+V+ F + EV P CSAK+LD + +Q
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 304 bits (778), Expect = 1e-82
Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%)
Query: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94
G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS
Sbjct: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78
Query: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154
S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R
Sbjct: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214
VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274
LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334
VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372
L + Y+V+ F + EV P CSAK+LD + +Q
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 304 bits (778), Expect = 1e-82
Identities = 158/338 (46%), Positives = 220/338 (65%), Gaps = 6/338 (1%)
Query: 35 GWAPAPVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFS 94
G+ P + + R R R + KDG CNV F ++ G+ Y+ D+FTT VD +WR M ++FS
Sbjct: 19 GYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFS 78
Query: 95 CSFLASWLLFGLAFWLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRS 154
S++ SWL+FG FWLIA HGDL P PC +V SF AFLF+LETQT+IGYG R
Sbjct: 79 LSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 155 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLC 214
VTEEC AV V+LQ I C+++ F++GA +AKMA +KR +T+ FS A++ +RD +LC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 215 LMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITI 274
LMWR+G+ R +H+VE VRAQLL+ EG + + +D+ + D+I LV+P+TI
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 275 VHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPV 334
VHEID SPLY L R +A+ +FE++V ++T + Q RSSY+P E+LWGHRF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 335 LFQRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQ 372
L + Y+V+ F + EV P CSAK+LD + +Q
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEV-YAPFCSAKQLDWKDQQ 350
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 298 bits (764), Expect = 5e-81
Identities = 148/342 (43%), Positives = 222/342 (64%), Gaps = 12/342 (3%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
+ RF+ K G CN+ N+ QG R+L D+FTT VD++WR ++F+ SFL SWLLF + +
Sbjct: 33 KARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
Query: 109 WLIASLHGDLAAPPPPAP----------CFSHVASFLAAFLFALETQTSIGYGVRSVTEE 158
WL+A HGD+ A + C ++V SF +AFLF++E Q +IG+G R +TEE
Sbjct: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
Query: 159 CPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWR 218
CP A+ ++LQ I G +++A ++G + K A+ +R ETL+FS +AV+A+R+ +LC M+R
Sbjct: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
Query: 219 VGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEI 278
VG+LR+S ++ A VR Q+++ TPEGE +P+ D+ V ++ IFLV+P+ I H I
Sbjct: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
Query: 279 DSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQR 338
D SPLY++ +LA D E++VILEG+VE T +TTQ R+SY+ E+ WGHRF ++ +
Sbjct: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
Query: 339 GSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSS 380
Y VDY F T +V P CSA+ELDE+ +L+ S
Sbjct: 332 EGVYSVDYSKFGNTVKV-AAPRCSARELDEKPSILIQTLQKS 372
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 289 bits (739), Expect = 4e-78
Identities = 143/331 (43%), Positives = 217/331 (65%), Gaps = 7/331 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGAR-YLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFG 105
R+R R V KDG CN+ F N+ Q + D++TT +D++WR+ +F +FL SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 LAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA 162
L ++ +A +H DL P A PC ++ +AFLF+LETQ +IGYG R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 163 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL 222
+ ++ Q I G ++++F+ GA++AK+++PKKR +T+ FS+NAV++ R +LCL+ RV NL
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 223 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS 282
R+S L+ +H+ +LL+ VTPEGE I LD +++ D G + +F +SP+TI H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 283 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ-RGSQ 341
P + + L + DFELVV L+G VE+T+ T Q R+SY+P E+LWG+RF P++ + + +
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 342 YEVDYRHFHRTYEV--PGTPVCSAKELDERA 370
Y VD+ +F +T EV P +C E D RA
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRA 348
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 289 bits (739), Expect = 4e-78
Identities = 143/331 (43%), Positives = 217/331 (65%), Gaps = 7/331 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGAR-YLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFG 105
R+R R V KDG CN+ F N+ Q + D++TT +D++WR+ +F +FL SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 LAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA 162
L ++ +A +H DL P A PC ++ +AFLF+LETQ +IGYG R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 163 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL 222
+ ++ Q I G ++++F+ GA++AK+++PKKR +T+ FS+NAV++ R +LCL+ RV NL
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 223 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS 282
R+S L+ +H+ +LL+ VTPEGE I LD +++ D G + +F +SP+TI H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 283 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ-RGSQ 341
P + + L + DFELVV L+G VE+T+ T Q R+SY+P E+LWG+RF P++ + + +
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 342 YEVDYRHFHRTYEV--PGTPVCSAKELDERA 370
Y VD+ +F +T EV P +C E D RA
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRA 348
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 289 bits (739), Expect = 4e-78
Identities = 143/331 (43%), Positives = 217/331 (65%), Gaps = 7/331 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGAR-YLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFG 105
R+R R V KDG CN+ F N+ Q + D++TT +D++WR+ +F +FL SW FG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 106 LAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA 162
L ++ +A +H DL P A PC ++ +AFLF+LETQ +IGYG R VTE+C A
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 163 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL 222
+ ++ Q I G ++++F+ GA++AK+++PKKR +T+ FS+NAV++ R +LCL+ RV NL
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 223 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS 282
R+S L+ +H+ +LL+ VTPEGE I LD +++ D G + +F +SP+TI H ID S
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 276
Query: 283 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ-RGSQ 341
P + + L + DFELVV L+G VE+T+ T Q R+SY+P E+LWG+RF P++ + + +
Sbjct: 277 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 336
Query: 342 YEVDYRHFHRTYEV--PGTPVCSAKELDERA 370
Y VD+ +F +T EV P +C E D RA
Sbjct: 337 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRA 367
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 289 bits (739), Expect = 4e-78
Identities = 143/331 (43%), Positives = 217/331 (65%), Gaps = 7/331 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGAR-YLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFG 105
R+R R V KDG CN+ F N+ Q + D++TT +D++WR+ +F +FL SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 LAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA 162
L ++ +A +H DL P A PC ++ +AFLF+LETQ +IGYG R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 163 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL 222
+ ++ Q I G ++++F+ GA++AK+++PKKR +T+ FS+NAV++ R +LCL+ RV NL
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 223 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS 282
R+S L+ +H+ +LL+ VTPEGE I LD +++ D G + +F +SP+TI H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 283 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ-RGSQ 341
P + + L + DFELVV L+G VE+T+ T Q R+SY+P E+LWG+RF P++ + + +
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 342 YEVDYRHFHRTYEV--PGTPVCSAKELDERA 370
Y VD+ +F +T EV P +C E D RA
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRA 348
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 289 bits (739), Expect = 4e-78
Identities = 143/331 (43%), Positives = 217/331 (65%), Gaps = 7/331 (2%)
Query: 47 RRRGRFVKKDGHCNVRFVNLGGQGAR-YLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFG 105
R+R R V KDG CN+ F N+ Q + D++TT +D++WR+ +F +FL SW FG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 106 LAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA 162
L ++ +A +H DL P A PC ++ +AFLF+LETQ +IGYG R VTE+C A
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 163 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL 222
+ ++ Q I G ++++F+ GA++AK+++PKKR +T+ FS+NAV++ R +LCL+ RV NL
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 223 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS 282
R+S L+ +H+ +LL+ VTPEGE I LD +++ D G + +F +SP+TI H ID S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 283 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ-RGSQ 341
P + + L + DFELVV L+G VE+T+ T Q R+SY+P E+LWG+RF P++ + + +
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 342 YEVDYRHFHRTYEV--PGTPVCSAKELDERA 370
Y VD+ +F +T EV P +C E D RA
Sbjct: 318 YRVDFHNFSKTVEVETPHCAMCLYNEKDVRA 348
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 263 bits (673), Expect = 2e-70
Identities = 139/320 (43%), Positives = 198/320 (61%), Gaps = 6/320 (1%)
Query: 40 PVQSPVGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLA 99
P+ P G RR R + KDG NVR ++ + YL DL+TT +D++WR+ LLFS +F
Sbjct: 19 PLMGP-GIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAG 77
Query: 100 SWLLFGLAFWLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVT 156
+W LFG+ ++L+A HGDL PPA PC V + AFLF+LE+QT+IGYG R ++
Sbjct: 78 TWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYIS 137
Query: 157 EECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLM 216
EECP A+ ++ Q + +L+ F+ G +AK+A+PKKR ET+ FS++AVVA + + CLM
Sbjct: 138 EECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLM 197
Query: 217 WRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVH 276
RV N+R+S L+ V +LLQ T EGE I L+ +V D +D FL+ P+T H
Sbjct: 198 IRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYH 257
Query: 277 EIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL- 335
+D SPL +L DFELV+IL G VE+T+ T Q R+SYLP E+LWG+ F P +
Sbjct: 258 VVDETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAIS 316
Query: 336 FQRGSQYEVDYRHFHRTYEV 355
+Y D+ F + +V
Sbjct: 317 LSASGKYIADFSLFDQVVKV 336
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 256 bits (653), Expect = 4e-68
Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ +
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165
+ IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225
+V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285
L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344
+L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372
D+ F + + P T C+ E + E+
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 256 bits (653), Expect = 4e-68
Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ +
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165
+ IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225
+V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285
L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344
+L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372
D+ F + + P T C+ E + E+
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 256 bits (653), Expect = 4e-68
Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%)
Query: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ +
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165
+ IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225
+V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285
L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344
+L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372
D+ F + + P T C+ E + E+
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 197 bits (502), Expect = 1e-50
Identities = 124/327 (37%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 45 VGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLF 104
+ +R R V KDGH ++ ++ +G YL D + +D+RWRWM L+FS SF+ WL+F
Sbjct: 13 LSQRYRRMVTKDGHSTLQ-MDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
Query: 105 GLAFWLIASLHGDL-----AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEEC 159
+ ++++A ++GDL A P C ++ SF AAF F+LETQ +IGYG + +C
Sbjct: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
Query: 160 PAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRV 219
P+A+A + +Q + G +L+AF+ GA +AK+A+PK R ++ F++ AVVA D + L+++V
Sbjct: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
Query: 220 GNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDG--GTDRIFLVSPITIVHE 277
N R S L V A L Q R E L VD DG + F + P+T H
Sbjct: 192 ANTRPSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
Query: 278 IDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ 337
I +SPL L + E + FELVV L M E T Q R+SYLP E++ H F +L
Sbjct: 247 ITPSSPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLL-T 304
Query: 338 RGS--QYEVDYRHFHRTYEVPGTPVCS 362
RGS +Y++ +F +T TP+ S
Sbjct: 305 RGSKGEYQIKMENFDKTVPEFPTPLVS 331
>gi|190341107 N-acetyltransferase 12 [Homo sapiens]
Length = 362
Score = 37.4 bits (85), Expect = 0.027
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 395 ALSCCQEEDEDDETEEGNGVETEDGAASPRVLT---PTLALTLPP 436
AL+CC E++EDDE EG G + G S V P L PP
Sbjct: 34 ALACCSEDEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPP 78
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,208,621
Number of Sequences: 37866
Number of extensions: 868643
Number of successful extensions: 3701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3575
Number of HSP's gapped (non-prelim): 79
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.