BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7019415 Sec61 alpha 1 subunit [Homo sapiens] (476 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7019415 Sec61 alpha 1 subunit [Homo sapiens] 934 0.0 gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens] 893 0.0 gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens] 836 0.0 gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens] 781 0.0 gi|4755125 aquaporin 4 isoform b [Homo sapiens] 35 0.11 gi|4502181 aquaporin 4 isoform a [Homo sapiens] 35 0.11 gi|4507685 transient receptor potential cation channel, subfamil... 32 1.3 gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens] 32 1.3 gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens] 32 1.3 gi|122937193 DNB5 [Homo sapiens] 30 4.8 gi|20070323 solute carrier family 30 (zinc transporter), member ... 30 6.3 gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens] 29 8.2 gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 29 8.2 >gi|7019415 Sec61 alpha 1 subunit [Homo sapiens] Length = 476 Score = 934 bits (2415), Expect = 0.0 Identities = 476/476 (100%), Positives = 476/476 (100%) Query: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 Query: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 Query: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 Query: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP 240 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP Sbjct: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP 240 Query: 241 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN 300 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN Sbjct: 241 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN 300 Query: 301 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH 360 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH Sbjct: 301 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH 360 Query: 361 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA 420 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA Sbjct: 361 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA 420 Query: 421 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF Sbjct: 421 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476 >gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens] Length = 476 Score = 893 bits (2308), Expect = 0.0 Identities = 445/476 (93%), Positives = 462/476 (97%) Query: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 M IKFLEVIKPFC +LPEIQKPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 Query: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 Query: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 MIITIGQ+IVYVMTGMYGDP+EMGAGICLLI IQLFVAGLIVLLLDELLQKGYGLGSGIS Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 Query: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP 240 LFIATNICETIVWKAFSPTT+NTGRG EFEGA+IALFHLLATRTDKVRALREAFYRQNLP Sbjct: 181 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP 240 Query: 241 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN 300 NLMNLIAT+FVFAVVIYFQGFRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSN Sbjct: 241 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN 300 Query: 301 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH 360 LYVISQMLS RFSGN LV+LLG W+D S GGPAR+YPVGGLCYYLSPPES G++ EDPVH Sbjct: 301 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH 360 Query: 361 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA 420 VVYI+FMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHR+TSMVHELNRYIPTA Sbjct: 361 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTA 420 Query: 421 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EVG MGAL F Sbjct: 421 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF 476 >gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens] Length = 454 Score = 836 bits (2160), Expect = 0.0 Identities = 424/476 (89%), Positives = 440/476 (92%), Gaps = 22/476 (4%) Query: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 M IKFLEVIKPFC +LPEIQKPERKI PLFGIMSSDSAD Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKI----------------------PLFGIMSSDSAD 38 Query: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG Sbjct: 39 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 98 Query: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 MIITIGQ+IVYVMTGMYGDP+EMGAGICLLI IQLFVAGLIVLLLDELLQKGYGLGSGIS Sbjct: 99 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 158 Query: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP 240 LFIATNICETIVWKAFSPTT+NTGRG EFEGA+IALFHLLATRTDKVRALREAFYRQNLP Sbjct: 159 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP 218 Query: 241 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN 300 NLMNLIAT+FVFAVVIYFQGFRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSN Sbjct: 219 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN 278 Query: 301 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH 360 LYVISQMLS RFSGN LV+LLG W+D S GGPAR+YPVGGLCYYLSPPES G++ EDPVH Sbjct: 279 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH 338 Query: 361 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTA 420 VVYI+FMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHR+TSMVHELNRYIPTA Sbjct: 339 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPTA 398 Query: 421 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EVG MGAL F Sbjct: 399 AAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF 454 >gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens] Length = 437 Score = 781 bits (2018), Expect = 0.0 Identities = 387/415 (93%), Positives = 403/415 (97%) Query: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 M IKFLEVIKPFC +LPEIQKPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60 Query: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120 Query: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 MIITIGQ+IVYVMTGMYGDP+EMGAGICLLI IQLFVAGLIVLLLDELLQKGYGLGSGIS Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 180 Query: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLP 240 LFIATNICETIVWKAFSPTT+NTGRG EFEGA+IALFHLLATRTDKVRALREAFYRQNLP Sbjct: 181 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLP 240 Query: 241 NLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSN 300 NLMNLIAT+FVFAVVIYFQGFRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSN Sbjct: 241 NLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSN 300 Query: 301 LYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVH 360 LYVISQMLS RFSGN LV+LLG W+D S GGPAR+YPVGGLCYYLSPPES G++ EDPVH Sbjct: 301 LYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVH 360 Query: 361 AVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNR 415 VVYI+FMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHR+TSMVHELNR Sbjct: 361 VVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNR 415 >gi|4755125 aquaporin 4 isoform b [Homo sapiens] Length = 301 Score = 35.4 bits (80), Expect = 0.11 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 4/99 (4%) Query: 123 ITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLF 182 I+I +S+ Y+ G + +GAGI L+T V GL V ++ L G+GL + L Sbjct: 88 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 143 Query: 183 IATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLA 221 I + TI S T TG G +A+ HL A Sbjct: 144 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 182 >gi|4502181 aquaporin 4 isoform a [Homo sapiens] Length = 323 Score = 35.4 bits (80), Expect = 0.11 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 4/99 (4%) Query: 123 ITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLF 182 I+I +S+ Y+ G + +GAGI L+T V GL V ++ L G+GL + L Sbjct: 110 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 165 Query: 183 IATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLA 221 I + TI S T TG G +A+ HL A Sbjct: 166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 204 >gi|4507685 transient receptor potential cation channel, subfamily C, member 1 [Homo sapiens] Length = 759 Score = 32.0 bits (71), Expect = 1.3 Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 5/39 (12%) Query: 336 YPVGGLCYYLSPPESFGSVLEDP-----VHAVVYIVFML 369 +PV LCY ++P FG ++ P +H Y F+L Sbjct: 327 WPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLL 365 >gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens] Length = 450 Score = 32.0 bits (71), Expect = 1.3 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 5/42 (11%) Query: 165 LDELLQKGYGLG-----SGISLFIATNICETIVWKAFSPTTV 201 L++L QKG L +GISLF+ ++C +WK + P V Sbjct: 327 LEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKV 368 >gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens] Length = 462 Score = 32.0 bits (71), Expect = 1.3 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 5/42 (11%) Query: 165 LDELLQKGYGLG-----SGISLFIATNICETIVWKAFSPTTV 201 L++L QKG L +GISLF+ ++C +WK + P V Sbjct: 339 LEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKV 380 >gi|122937193 DNB5 [Homo sapiens] Length = 748 Score = 30.0 bits (66), Expect = 4.8 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 278 TYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSD--TSSGGPARA 335 +Y ++ Y + P++LQ L LY + +S G LL LLG WSD TS G R Sbjct: 100 SYAMETAYVT--PVLLQMGLPDQLYSLVWFISP-ILGFLLQPLLGAWSDRCTSRFGRRRP 156 Query: 336 Y 336 + Sbjct: 157 F 157 >gi|20070323 solute carrier family 30 (zinc transporter), member 5 isoform 1 [Homo sapiens] Length = 765 Score = 29.6 bits (65), Expect = 6.3 Identities = 34/124 (27%), Positives = 50/124 (40%), Gaps = 17/124 (13%) Query: 345 LSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGH 404 + PPE +L PV IV ++G CAF S G+S M GH Sbjct: 512 IDPPELDTHMLT-PVSVGGLIVNLIGICAF-SHAHSHAHGASQGSCHSSDHSHSHHMHGH 569 Query: 405 RETSMVHELNRYIPTAAAFGGLCIGA----LSVLADFLGAIGSGTGILLAVTIIYQYFEI 460 + H +A GG+ L VLAD LG+IG ++ T++ + F Sbjct: 570 SDHGHGHS------HGSAGGGMNANMRGVFLHVLADTLGSIG-----VIVSTVLIEQFGW 618 Query: 461 FVKE 464 F+ + Sbjct: 619 FIAD 622 >gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens] Length = 574 Score = 29.3 bits (64), Expect = 8.2 Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 6/36 (16%) Query: 325 SDTSSGGPARAYPVGGLCYYLSP--PESFGSVLEDP 358 SD GP RA+P GG Y P PE+F EDP Sbjct: 369 SDEQPQGPERAFPSGGAVYGAQPSQPEAF----EDP 400 >gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] Length = 3639 Score = 29.3 bits (64), Expect = 8.2 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 353 SVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHE 412 S+ EDP HA L C F+K +V S + A +L + ++ RGH MV + Sbjct: 1723 SLGEDPEHA-------LHLCTKFAKFQHQVEMGSQRVAACRLLAESLLERGHSAGPMVRQ 1775 Query: 413 LNRYIPTA 420 + + TA Sbjct: 1776 RQQDLQTA 1783 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.142 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,027,964 Number of Sequences: 37866 Number of extensions: 660038 Number of successful extensions: 1704 Number of sequences better than 10.0: 13 Number of HSP's better than 10.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1699 Number of HSP's gapped (non-prelim): 14 length of query: 476 length of database: 18,247,518 effective HSP length: 106 effective length of query: 370 effective length of database: 14,233,722 effective search space: 5266477140 effective search space used: 5266477140 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.