Search of human proteins with 70166634

Search of human proteins with 70166634

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70166634 pseudouridine synthase 1 isoform 2 [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70166634 pseudouridine synthase 1 isoform 2 [Homo sapiens]         822   0.0  
gi|70166599 pseudouridine synthase 1 isoform 2 [Homo sapiens]         822   0.0  
gi|70166645 pseudouridine synthase 1 isoform 1 [Homo sapiens]         822   0.0  
gi|199559785 pseudouridylate synthase 3 [Homo sapiens]                 78   2e-14
gi|23503259 pseudouridylate synthase-like 1 [Homo sapiens]             59   8e-09
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            34   0.27 
gi|222831660 family with sequence similarity 171, member A2 [Hom...    33   0.45 
gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo sa...    32   1.0  
gi|142976757 immediate early response 5 [Homo sapiens]                 32   1.3  
gi|169206224 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|239754911 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|169206527 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|239749451 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|113424187 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|239743581 PREDICTED: hypothetical protein [Homo sapiens]            31   2.3  
gi|4885075 atonal homolog 1 [Homo sapiens]                             30   2.9  
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]           30   3.8  
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]           30   3.8  
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]           30   3.8  
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]           30   3.8  
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  29   6.6  
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  29   6.6  
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  29   6.6  
gi|93141214 sodium channel, voltage-gated, type II, alpha isofor...    29   8.6  
gi|93141212 sodium channel, voltage-gated, type II, alpha isofor...    29   8.6  
gi|93141210 sodium channel, voltage-gated, type II, alpha isofor...    29   8.6  

>gi|70166634 pseudouridine synthase 1 isoform 2 [Homo sapiens]
          Length = 399

 Score =  822 bits (2123), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 60
           MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL
Sbjct: 1   MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 60

Query: 61  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 120
           LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG
Sbjct: 61  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 120

Query: 121 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 180
           VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF
Sbjct: 121 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 180

Query: 181 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 240
           AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC
Sbjct: 181 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 240

Query: 241 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 300
           EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA
Sbjct: 241 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 300

Query: 301 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 360
           PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA
Sbjct: 301 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 360

Query: 361 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 399
           QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD
Sbjct: 361 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 399


>gi|70166599 pseudouridine synthase 1 isoform 2 [Homo sapiens]
          Length = 399

 Score =  822 bits (2123), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 60
           MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL
Sbjct: 1   MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 60

Query: 61  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 120
           LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG
Sbjct: 61  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 120

Query: 121 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 180
           VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF
Sbjct: 121 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 180

Query: 181 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 240
           AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC
Sbjct: 181 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 240

Query: 241 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 300
           EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA
Sbjct: 241 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 300

Query: 301 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 360
           PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA
Sbjct: 301 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 360

Query: 361 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 399
           QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD
Sbjct: 361 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 399


>gi|70166645 pseudouridine synthase 1 isoform 1 [Homo sapiens]
          Length = 427

 Score =  822 bits (2123), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 60
           MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL
Sbjct: 29  MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVL 88

Query: 61  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 120
           LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG
Sbjct: 89  LMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKG 148

Query: 121 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 180
           VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF
Sbjct: 149 VSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTF 208

Query: 181 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 240
           AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC
Sbjct: 209 AFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYC 268

Query: 241 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 300
           EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA
Sbjct: 269 EEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKA 328

Query: 301 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 360
           PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA
Sbjct: 329 PGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMA 388

Query: 361 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 399
           QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD
Sbjct: 389 QWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD 427


>gi|199559785 pseudouridylate synthase 3 [Homo sapiens]
          Length = 481

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 78/295 (26%), Positives = 115/295 (38%), Gaps = 78/295 (26%)

Query: 55  KRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRC 114
           +R + L +AY G GY G      ++   TIE+ L  AL ++  +     E  +  ++ RC
Sbjct: 62  RRHVALRIAYMGWGYQGFASQENTNN--TIEEKLFEALTKTRLV-----ESRQTSNYHRC 114

Query: 115 ARTDKGVSAAGQVVSLKVWL-------IDDILEK---------------INSHLPSHIRI 152
            RTDKGVSA GQV+SL +          +D   K               +N  LP  IRI
Sbjct: 115 GRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRI 174

Query: 153 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK 212
           L    V   F+++  C  RTY Y  P       D D+    Y                Y 
Sbjct: 175 LAWAPVEPSFSARFSCLERTYRYFFP-----RADLDIVTMDYAAQK------------YV 217

Query: 213 GTHNFHNFTS-------------------QKGPQDPSACRYILEMYCEEPFVREGLEFAV 253
           GTH+F N                      Q   Q P   R+      +EPF     +   
Sbjct: 218 GTHDFRNLCKMDVANGVINFQRTILSAQVQLVGQSPGEGRW------QEPF-----QLCQ 266

Query: 254 IRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLE 308
             V GQ+F+ HQ+R M+ ++  I +G     +++     EK   P+ P   + +E
Sbjct: 267 FEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEK--NPQKPQYSMAVE 319


>gi|23503259 pseudouridylate synthase-like 1 [Homo sapiens]
          Length = 303

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 71/281 (25%), Positives = 116/281 (41%), Gaps = 34/281 (12%)

Query: 55  KRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRC 114
           + + ++   Y G  ++G+    G+ +   +++ L  A  R   +          + F   
Sbjct: 11  RARYLVYFQYVGTDFNGVAAVRGTQRAVGVQNYLEEAAERLNSV--------EPVRFTIS 62

Query: 115 ARTDKGVSAAGQVVSLKV--------WLIDDILEKINSHLPSH-IRILGLKRVTGGFNSK 165
           +RTD GV A      L V        +  + + E +N+HL    IR+L   RV   F+++
Sbjct: 63  SRTDAGVHALSNAAHLDVQRRSGRPPFPPEVLAEALNTHLRHPAIRVLRAFRVPSDFHAR 122

Query: 166 NRCDARTYCYLLPTFAFAHKDRDVQDET--YRLSAETLQQVNRLLACYK--GTHNFHNFT 221
           +   +RTY Y L T      +  V +    + L A+ L  V    A     GTH+F  F 
Sbjct: 123 HAATSRTYLYRLATGCHRRDELPVFERNLCWTLPADCLDMVAMQEAAQHLLGTHDFSAFQ 182

Query: 222 SQKGPQDPSACRYILEMYCE--------EPFVREGLEFAVIRVKGQSFMMHQIRKMVGLV 273
           S   P  PS  R +  +            P     L F  +  + QSF+  Q+R+M  ++
Sbjct: 183 SAGSPV-PSPVRTLRRVSVSPGQASPLVTPEESRKLRFWNLEFESQSFLYRQVRRMTAVL 241

Query: 274 VAIVKG-YAP---ESVLERSWGTEKVDVPKAPGLGLVLERV 310
           VA+  G  AP   +++LE      K     AP  GL L+ V
Sbjct: 242 VAVGLGALAPAQVKTILESQDPLGKHQTRVAPAHGLFLKSV 282


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 268  KMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEP 327
            K+V   V I+KG  P+ V     GT KVD    PG GL+ +  HF +   +F  D + + 
Sbjct: 2949 KLVIEAVCIMKGIKPKKVPGEKPGT-KVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDV 3007

Query: 328  LDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATAL 376
            +  A +        EE    TI    +   S+ QW+  +  ++F A A+
Sbjct: 3008 VIKAIQP---YIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAV 3053


>gi|222831660 family with sequence similarity 171, member A2 [Homo
           sapiens]
          Length = 826

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 14/49 (28%), Positives = 21/49 (42%)

Query: 341 KEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPL 389
           +E   +P  +GTE        WL  +P+   S   LT  GT   +  P+
Sbjct: 183 QEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPI 231


>gi|10440566 leucine zipper, putative tumor suppressor 1 [Homo
           sapiens]
          Length = 596

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 11/128 (8%)

Query: 266 IRKMVGLVVAIVKGYAPESVLERSWG--TEKVDVPKAPGLGLVLERVHFEKYNQRFGNDG 323
           +R+ V L+   ++    ++ L R  G  T   DVP    L   LER+  E   +R G+D 
Sbjct: 464 LREKVNLLEQELQELRAQAALARDMGPPTFPEDVP---ALQRELERLRAELREERQGHDQ 520

Query: 324 L-----HEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTA 378
           +     HE L W +E+ KV  ++++     +   +R++R + + L  L   + +   L  
Sbjct: 521 MSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQR-LEKALQQLARGDSAGEPLEV 579

Query: 379 GGTGAKVP 386
              GA +P
Sbjct: 580 DLEGADIP 587


>gi|142976757 immediate early response 5 [Homo sapiens]
          Length = 327

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 11/78 (14%)

Query: 6   EPPPAGAACPQDRRSCSGRAGGDRVW--EDGEHPAKKLK-------SGGDEERREKPPKR 56
           EPP   A CP  R+ C+   GG        G  P KK +       SGG+++  E+    
Sbjct: 207 EPPAPPAVCP--RKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETG 264

Query: 57  KIVLLMAYSGKGYHGMQR 74
            +  L++  G  + G+ R
Sbjct: 265 NVANLISIFGSSFSGLLR 282


>gi|169206224 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 318

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 12/87 (13%)

Query: 38  AKKLKSGGDEERREKPPKR------KIVLLMAYSG-----KGYHGMQRNVGSSQFKTIED 86
           A+++ + G   R  + P+R       ++ + A++G     KG  G+QR VG+++F  I  
Sbjct: 149 ARRIATPGLGARASRSPERVKRTTCPVLQIEAFAGRDIGKKGGEGVQRKVGTAEF-GISA 207

Query: 87  DLVSALVRSGCIPENHGEDMRKMSFQR 113
           +    + RS    ++HG  + K  +QR
Sbjct: 208 ETGKKINRSTSYMQSHGNCLGKRKWQR 234


>gi|239754911 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/28 (46%), Positives = 15/28 (53%)

Query: 7   PPPAGAACPQDRRSCSGRAGGDRVWEDG 34
           PPP   +C   RRSC+ R GG   W  G
Sbjct: 150 PPPLPTSCHWARRSCALRRGGAASWRRG 177


>gi|169206527 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 318

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 12/87 (13%)

Query: 38  AKKLKSGGDEERREKPPKR------KIVLLMAYSG-----KGYHGMQRNVGSSQFKTIED 86
           A+++ + G   R  + P+R       ++ + A++G     KG  G+QR VG+++F  I  
Sbjct: 149 ARRIATPGLGARASRSPERVKRTTCPVLQIEAFAGRDIGKKGGEGVQRKVGTAEF-GISA 207

Query: 87  DLVSALVRSGCIPENHGEDMRKMSFQR 113
           +    + RS    ++HG  + K  +QR
Sbjct: 208 ETGKKINRSTSYMQSHGNCLGKRKWQR 234


>gi|239749451 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/28 (46%), Positives = 15/28 (53%)

Query: 7   PPPAGAACPQDRRSCSGRAGGDRVWEDG 34
           PPP   +C   RRSC+ R GG   W  G
Sbjct: 150 PPPLPTSCHWARRSCALRRGGAASWRRG 177


>gi|113424187 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 268

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 12/87 (13%)

Query: 38  AKKLKSGGDEERREKPPKR------KIVLLMAYSG-----KGYHGMQRNVGSSQFKTIED 86
           A+++ + G   R  + P+R       ++ + A++G     KG  G+QR VG+++F  I  
Sbjct: 99  ARRIATPGLGARASRSPERVKRTTCPVLQIEAFAGRDIGKKGGEGVQRKVGTAEF-GISA 157

Query: 87  DLVSALVRSGCIPENHGEDMRKMSFQR 113
           +    + RS    ++HG  + K  +QR
Sbjct: 158 ETGKKINRSTSYMQSHGNCLGKRKWQR 184


>gi|239743581 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/28 (46%), Positives = 15/28 (53%)

Query: 7   PPPAGAACPQDRRSCSGRAGGDRVWEDG 34
           PPP   +C   RRSC+ R GG   W  G
Sbjct: 150 PPPLPTSCHWARRSCALRRGGAASWRRG 177


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 12/96 (12%)

Query: 2   AGNAEPPPAGAACPQD----RRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRK 57
           +G  +PPP  A+C  D    R + S   G       G   A    SGG +  R  PP   
Sbjct: 219 SGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQA----SGGSQ--RPTPPGSC 272

Query: 58  IVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALV 93
                A +  G + +Q  + +  F T ED  ++A++
Sbjct: 273 RTRFSAPASAGGYSVQ--LDALHFSTFEDSALTAMM 306


>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
          Length = 1011

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 280 YAPESVLERSWGTEKVDVPKAPGLGLV-LER 309
           Y+P S L R+  T++VDVP  PG+ +  LER
Sbjct: 868 YSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 898


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 280 YAPESVLERSWGTEKVDVPKAPGLGLV-LER 309
           Y+P S L R+  T++VDVP  PG+ +  LER
Sbjct: 930 YSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 960


>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 280 YAPESVLERSWGTEKVDVPKAPGLGLV-LER 309
           Y+P S L R+  T++VDVP  PG+ +  LER
Sbjct: 874 YSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 904


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 280 YAPESVLERSWGTEKVDVPKAPGLGLV-LER 309
           Y+P S L R+  T++VDVP  PG+ +  LER
Sbjct: 855 YSPPSTLPRNSPTKRVDVPTTPGVPMTSLER 885


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 1/74 (1%)

Query: 327 PLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIH-NFSATALTAGGTGAKV 385
           P +  +   +V A K+      +   E   +  A  L T   H + S+ A  A G GA  
Sbjct: 43  PREARKSLAEVEAGKDASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQ 102

Query: 386 PSPLEGSEGDGDTD 399
            SPLEGSE + + D
Sbjct: 103 ASPLEGSEAEEEED 116


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 1/74 (1%)

Query: 327 PLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIH-NFSATALTAGGTGAKV 385
           P +  +   +V A K+      +   E   +  A  L T   H + S+ A  A G GA  
Sbjct: 43  PREARKSLAEVEAGKDASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQ 102

Query: 386 PSPLEGSEGDGDTD 399
            SPLEGSE + + D
Sbjct: 103 ASPLEGSEAEEEED 116


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 1/74 (1%)

Query: 327 PLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIH-NFSATALTAGGTGAKV 385
           P +  +   +V A K+      +   E   +  A  L T   H + S+ A  A G GA  
Sbjct: 43  PREARKSLAEVEAGKDASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQ 102

Query: 386 PSPLEGSEGDGDTD 399
            SPLEGSE + + D
Sbjct: 103 ASPLEGSEAEEEED 116


>gi|93141214 sodium channel, voltage-gated, type II, alpha isoform 2
           [Homo sapiens]
          Length = 2005

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 6   EPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRK 57
           E   A AA   + R  SG AGG  V+ +    A KL S  ++E + +  K+K
Sbjct: 459 EAQAAAAAASAESRDFSG-AGGIGVFSESSSVASKLSSKSEKELKNRRKKKK 509


>gi|93141212 sodium channel, voltage-gated, type II, alpha isoform 1
           [Homo sapiens]
          Length = 2005

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 6   EPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRK 57
           E   A AA   + R  SG AGG  V+ +    A KL S  ++E + +  K+K
Sbjct: 459 EAQAAAAAASAESRDFSG-AGGIGVFSESSSVASKLSSKSEKELKNRRKKKK 509


>gi|93141210 sodium channel, voltage-gated, type II, alpha isoform 1
           [Homo sapiens]
          Length = 2005

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 6   EPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRK 57
           E   A AA   + R  SG AGG  V+ +    A KL S  ++E + +  K+K
Sbjct: 459 EAQAAAAAASAESRDFSG-AGGIGVFSESSSVASKLSSKSEKELKNRRKKKK 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,075,973
Number of Sequences: 37866
Number of extensions: 786071
Number of successful extensions: 1913
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1897
Number of HSP's gapped (non-prelim): 28
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.