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Search of human proteins with 13899342
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899342 solute carrier [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899342 solute carrier [Homo sapiens] 628 e-180
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 402 e-112
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 205 4e-53
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 205 4e-53
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 202 3e-52
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 112 4e-25
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 107 1e-23
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 102 6e-22
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 100 2e-21
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 98 1e-20
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 97 1e-20
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 97 2e-20
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 96 3e-20
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 95 7e-20
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 95 7e-20
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 92 5e-19
gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 91 1e-18
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 91 2e-18
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 89 7e-18
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 88 1e-17
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 87 2e-17
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 87 2e-17
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 86 3e-17
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 86 4e-17
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 86 4e-17
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 86 6e-17
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 85 7e-17
gi|13259541 uncoupling protein 2 [Homo sapiens] 82 5e-16
gi|11225256 uncoupling protein 1 [Homo sapiens] 82 5e-16
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 79 4e-15
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 628 bits (1620), Expect = e-180
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60
MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG
Sbjct: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60
Query: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120
FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT
Sbjct: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120
Query: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180
CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA
Sbjct: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180
Query: 181 GLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVT 240
GLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVT
Sbjct: 181 GLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVT 240
Query: 241 PLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQG 300
PLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQG
Sbjct: 241 PLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQG 300
Query: 301 VYFIGIGERILKCFD 315
VYFIGIGERILKCFD
Sbjct: 301 VYFIGIGERILKCFD 315
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 402 bits (1034), Expect = e-112
Identities = 208/317 (65%), Positives = 249/317 (78%), Gaps = 8/317 (2%)
Query: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ-HGKAMYKGMIDCLMKTARAE 59
M + +S+ AKLINGG+AGL+GVTCVFPIDLAKTRLQNQ +G+ +Y M DCL+KT R+E
Sbjct: 1 MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSE 60
Query: 60 GFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVV 119
G+FGMYRGAAVNLTLVTPEKAIKLAANDFFR L +DG + L EMLAGCGAG CQV+V
Sbjct: 61 GYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIV 120
Query: 120 TCPMEMLKIQLQDAGRLAVHH-----QGSASAPSTSRSYTTGSASTHRRPSATLIAWELL 174
T PMEMLKIQLQDAGR+A QG SA ++ A+ RP+AT + +LL
Sbjct: 121 TTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAP--RPTATQLTRDLL 178
Query: 175 RTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSI 234
R++G+AGLY+GLGATLLRD+PFS++YFPLFANLN LG K+ F SF++GCVAGS
Sbjct: 179 RSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSA 238
Query: 235 AAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPL 294
AAVAV P DV+KTR+Q+L++G+ ED YSGI DCARK+ EGPSAF+KGA CRALVIAPL
Sbjct: 239 AAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPL 298
Query: 295 FGIAQGVYFIGIGERIL 311
FGIAQ VYF+GI E +L
Sbjct: 299 FGIAQVVYFLGIAESLL 315
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 205 bits (522), Expect = 4e-53
Identities = 127/294 (43%), Positives = 159/294 (54%), Gaps = 34/294 (11%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQH------GKAMYKGMIDCLMKTARAEGFFGMYRGA 68
G VAG VG T V+PIDL KTR+QNQ G+ MYK DC K R EGFFG+YRG
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128
L V PEKAIKL NDF R M L E+LAG AG QV+ T P+E++KI
Sbjct: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 454
Query: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188
+LQ AG + TTG + A ++R G G+Y+G A
Sbjct: 455 RLQVAGEI-----------------TTG---------PRVSALSVVRDLGFFGIYKGAKA 488
Query: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248
LRDIPFS IYFP +A++ NE G+ S ++G +AG AA VTP DV+KTR
Sbjct: 489 CFLRDIPFSAIYFPCYAHVKASFANE-DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 547
Query: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302
+Q + G+ YSG+ DC RK+ +EGP A KGAG R +P FG+ Y
Sbjct: 548 LQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 600
Score = 52.0 bits (123), Expect = 7e-07
Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69
L+ G +AG+ + V P D+ KTRLQ + G+ Y G+IDC K R EG +++GA
Sbjct: 524 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 583
Query: 70 VNLTLVTPEKAIKLAANDFFRR 91
+ +P+ + L + +R
Sbjct: 584 ARVFRSSPQFGVTLLTYELLQR 605
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 3 HQDLSI--TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60
H+D S+ A+++ GG AG V P+++ K RL Q + G + R G
Sbjct: 421 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLG 478
Query: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120
FFG+Y+GA P AI + + Q + +LAG AGM +
Sbjct: 479 FFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLV 538
Query: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180
P +++K +LQ A R ++ +G R+ +LR +G
Sbjct: 539 TPADVIKTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPK 576
Query: 181 GLYRGLGATLLRDIP 195
L++G GA + R P
Sbjct: 577 ALWKGAGARVFRSSP 591
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275
A A+ F G VAG++ A AV P+D++KTR+Q + +GE MY DC +K+ E
Sbjct: 326 AESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYE 385
Query: 276 GPSAFMKGAGCRALVIAP 293
G +G + L +AP
Sbjct: 386 GFFGLYRGLLPQLLGVAP 403
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 205 bits (522), Expect = 4e-53
Identities = 127/294 (43%), Positives = 159/294 (54%), Gaps = 34/294 (11%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQH------GKAMYKGMIDCLMKTARAEGFFGMYRGA 68
G VAG VG T V+PIDL KTR+QNQ G+ MYK DC K R EGFFG+YRG
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128
L V PEKAIKL NDF R M L E+LAG AG QV+ T P+E++KI
Sbjct: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI 455
Query: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188
+LQ AG + TTG + A ++R G G+Y+G A
Sbjct: 456 RLQVAGEI-----------------TTG---------PRVSALSVVRDLGFFGIYKGAKA 489
Query: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248
LRDIPFS IYFP +A++ NE G+ S ++G +AG AA VTP DV+KTR
Sbjct: 490 CFLRDIPFSAIYFPCYAHVKASFANE-DGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 548
Query: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302
+Q + G+ YSG+ DC RK+ +EGP A KGAG R +P FG+ Y
Sbjct: 549 LQVAARA-GQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTY 601
Score = 52.0 bits (123), Expect = 7e-07
Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69
L+ G +AG+ + V P D+ KTRLQ + G+ Y G+IDC K R EG +++GA
Sbjct: 525 LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAG 584
Query: 70 VNLTLVTPEKAIKLAANDFFRR 91
+ +P+ + L + +R
Sbjct: 585 ARVFRSSPQFGVTLLTYELLQR 606
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 3 HQDLSI--TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEG 60
H+D S+ A+++ GG AG V P+++ K RL Q + G + R G
Sbjct: 422 HKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLG 479
Query: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVT 120
FFG+Y+GA P AI + + Q + +LAG AGM +
Sbjct: 480 FFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLV 539
Query: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180
P +++K +LQ A R ++ +G R+ +LR +G
Sbjct: 540 TPADVIKTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPK 577
Query: 181 GLYRGLGATLLRDIP 195
L++G GA + R P
Sbjct: 578 ALWKGAGARVFRSSP 592
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275
A A+ F G VAG++ A AV P+D++KTR+Q + +GE MY DC +K+ E
Sbjct: 327 AESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYE 386
Query: 276 GPSAFMKGAGCRALVIAP 293
G +G + L +AP
Sbjct: 387 GFFGLYRGLLPQLLGVAP 404
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 202 bits (514), Expect = 3e-52
Identities = 127/294 (43%), Positives = 157/294 (53%), Gaps = 34/294 (11%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKA------MYKGMIDCLMKTARAEGFFGMYRGA 68
G VAG VG T V+PIDL KTR+QNQ G MYK DC K R EGFFG+YRG
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKI 128
L V PEKAIKL NDF R L E+LAG AG QV+ T P+E++KI
Sbjct: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
Query: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188
+LQ AG + TTG + A +LR G+ GLY+G A
Sbjct: 453 RLQVAGEI-----------------TTG---------PRVSALNVLRDLGIFGLYKGAKA 486
Query: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248
LRDIPFS IYFP++A+ L +E G + +G +AG AA VTP DV+KTR
Sbjct: 487 CFLRDIPFSAIYFPVYAHCKLLLADE-NGHVGGLNLLAAGAMAGVPAASLVTPADVIKTR 545
Query: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302
+Q + G+ YSG+ DC RK+ +EGPSAF KG R +P FG+ Y
Sbjct: 546 LQVAARA-GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTY 598
Score = 49.7 bits (117), Expect = 3e-06
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69
L G +AG+ + V P D+ KTRLQ + G+ Y G+IDC K R EG ++G A
Sbjct: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTA 581
Query: 70 VNLTLVTPEKAIKLAANDFFRR 91
+ +P+ + L + +R
Sbjct: 582 ARVFRSSPQFGVTLVTYELLQR 603
Score = 48.5 bits (114), Expect = 8e-06
Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKG---LGEDMYSGITDCARKLWIQE 275
A A+ F G VAG++ A AV P+D++KTR+Q + +GE MY DC +K+ E
Sbjct: 324 AESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYE 383
Query: 276 GPSAFMKGAGCRALVIAP 293
G +G + + +AP
Sbjct: 384 GFFGLYRGLIPQLIGVAP 401
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 26/189 (13%)
Query: 8 ITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRG 67
+ A+++ GG AG V P+++ K RL Q + G + R G FG+Y+G
Sbjct: 426 LPAEVLAGGCAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALNVLRDLGIFGLYKG 483
Query: 68 AAVNLTLVTPEKAIKLAANDFFRRLLM-EDGMQRNLKMEMLAGCGAGMCQVVVTCPMEML 126
A P AI + LL E+G L + + AG AG+ + P +++
Sbjct: 484 AKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL-LAAGAMAGVPAASLVTPADVI 542
Query: 127 KIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGL 186
K +LQ A R ++ +G R+ +LR +G + ++G
Sbjct: 543 KTRLQVAAR-------------AGQTTYSGVIDCFRK---------ILREEGPSAFWKGT 580
Query: 187 GATLLRDIP 195
A + R P
Sbjct: 581 AARVFRSSP 589
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 112 bits (280), Expect = 4e-25
Identities = 88/287 (30%), Positives = 138/287 (48%), Gaps = 34/287 (11%)
Query: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQ--NQHGKAMYKGMIDCLMKTARA 58
+TH +I A GG+AG + + FP + KT+LQ + Y+G+ DC+ +T R+
Sbjct: 22 LTHPGKAILA----GGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRS 77
Query: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQ-V 117
G G+YRG + L P+ A++ +F + + + + +L G GAG+ + V
Sbjct: 78 HGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAV 137
Query: 118 VVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQ 177
VV CPME +K++ +H Q S + R + G E++R Q
Sbjct: 138 VVVCPMETIKVKF-------IHDQTSPN--PKYRGFFHG-------------VREIVREQ 175
Query: 178 GLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGK-ASFAHSFVSGCVAGSIAA 236
GL G Y+GL AT+L+ I F + +L N + K + + V G +AG+ +
Sbjct: 176 GLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASV 235
Query: 237 VAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
TPLDV+KTR+Q GL Y DC ++ +EG AF KG
Sbjct: 236 FGNTPLDVIKTRMQ----GLEAHKYRNTWDCGLQILKKEGLKAFYKG 278
Score = 37.4 bits (85), Expect = 0.017
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Query: 12 LINGGVAGLVGVTCVF---PIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGA 68
LI G + G VF P+D+ KTR+Q Y+ DC ++ + EG Y+G
Sbjct: 221 LITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHK-YRNTWDCGLQILKKEGLKAFYKGT 279
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLL 93
L V + AI D +LL
Sbjct: 280 VPRLGRVCLDVAIVFVIYDEVVKLL 304
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 107 bits (267), Expect = 1e-23
Identities = 83/288 (28%), Positives = 135/288 (46%), Gaps = 29/288 (10%)
Query: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA---MYKGMIDCLMKTARAEGFFGMYRG 67
+++ GG AGLV + + P+D+ KTR Q Q YK ++D + EG FG Y+G
Sbjct: 16 QIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKG 75
Query: 68 AAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK 127
+ TP++A+K + +++LL + L +AG G+G+ + +V P E++K
Sbjct: 76 ILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTF-AIAGLGSGLTEAIVVNPFEVVK 134
Query: 128 IQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQ--GLAGLYRG 185
+ LQ A R Q PS A ++++ + GL GL +G
Sbjct: 135 VGLQ-ANRNTFAEQ----------------------PSTVGYARQIIKKEGWGLQGLNKG 171
Query: 186 LGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVL 245
L ATL R F+++YF + N+ N+ F F G ++G+IA+V P DV
Sbjct: 172 LTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVA 231
Query: 246 KTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAP 293
K+RIQ + GE Y ++ +EG A KG + + + P
Sbjct: 232 KSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGP 279
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/165 (21%), Positives = 72/165 (43%), Gaps = 25/165 (15%)
Query: 95 EDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYT 154
E + R +++AG AG+ ++ + P++++K + Q Q A+ P++ +S
Sbjct: 6 EVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQ--------IQRCATDPNSYKSLV 57
Query: 155 TGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNN-LGFN 213
+ + +GL G Y+G+ +L + P + F F LG+
Sbjct: 58 DSFRM-------------IFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYV 104
Query: 214 ELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGE 258
L+ +FA ++G +G A+ V P +V+K +Q + E
Sbjct: 105 SLSPALTFA---IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAE 146
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/62 (32%), Positives = 30/62 (48%)
Query: 222 AHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFM 281
+ V+G AG + + PLDV+KTR Q + + Y + D R ++ EG F
Sbjct: 14 SRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFY 73
Query: 282 KG 283
KG
Sbjct: 74 KG 75
Score = 34.7 bits (78), Expect = 0.11
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQH---GKAMYKGMIDCLMKTARAEGFFGMYRGA 68
L++G +A ++ + P D+AK+R+Q G+ Y+ + + EG +Y+G
Sbjct: 215 LLSGTIASVINI----PFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGL 270
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLLMED 96
+ + P A+ L ++ L E+
Sbjct: 271 LPKIMRLGPGGAVMLLVYEYTYSWLQEN 298
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 102 bits (253), Expect = 6e-22
Identities = 84/316 (26%), Positives = 136/316 (43%), Gaps = 42/316 (13%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQHG------KAMYKGMIDCLMKTARAEGFFGMY 65
L+ GGVA V T V PI+ K LQ Q +A YKGM+DCL++ R +GFF +
Sbjct: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
Query: 66 RGAAVNLTLVTPEKAIKLAANDFFRRLLM-----EDGMQRNLKMEMLAGCGAGMCQVVVT 120
RG N+ P +A+ A D +++L M E R + +G AG + V
Sbjct: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
Query: 121 CPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGL 179
P++ + +L D G+ P + G ++ ++ G+
Sbjct: 144 YPLDFARTRLGVDIGK----------GPEERQFKGLGDC-----------IMKIAKSDGI 182
Query: 180 AGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAV 239
AGLY+G G ++ I + YF + + G K F SF V + + +
Sbjct: 183 AGLYQGFGVSVQGIIVYRASYFGAYDTVK--GLLPKPKKTPFLVSFFIAQVVTTCSGILS 240
Query: 240 TPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA------GCRALVIAP 293
P D ++ R+ ++ G + Y G DC K++ EG S+F +GA G ++
Sbjct: 241 YPFDTVRRRMM-MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLV 299
Query: 294 LFGIAQGVYFIGIGER 309
L+ + + I IG R
Sbjct: 300 LYDKIKEFFHIDIGGR 315
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/190 (27%), Positives = 84/190 (44%), Gaps = 33/190 (17%)
Query: 10 AKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA----MYKGMIDCLMKTARAEGFFGMY 65
A L +GG AG + V+P+D A+TRL GK +KG+ DC+MK A+++G G+Y
Sbjct: 127 ANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLY 186
Query: 66 RGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEM 125
+G V++ + +A A D + LL + L +A QVV TC
Sbjct: 187 QGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIA-------QVVTTC---- 235
Query: 126 LKIQLQDAGRLAVHHQGSASAP--STSRSYTTGSASTHRRPSATLIAW-ELLRTQGLAGL 182
G S P + R S R+ TL + ++ + +G++
Sbjct: 236 ---------------SGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSF 280
Query: 183 YRGLGATLLR 192
+RG + +LR
Sbjct: 281 FRGAFSNVLR 290
Score = 45.1 bits (105), Expect = 8e-05
Identities = 47/186 (25%), Positives = 72/186 (38%), Gaps = 23/186 (12%)
Query: 105 EMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRP 164
++LAG A P+E +K+ LQ Q S+ S Y R P
Sbjct: 23 DLLAGGVAAAVSKTAVAPIERVKLLLQV--------QASSKQISPEARYKGMVDCLVRIP 74
Query: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHS 224
R QG +RG A ++R P + F L + + + F
Sbjct: 75 ----------REQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRW 124
Query: 225 FV----SGCVAGSIAAVAVTPLDVLKTRIQT-LKKGLGEDMYSGITDCARKLWIQEGPSA 279
F+ SG AG+ + V PLD +TR+ + KG E + G+ DC K+ +G +
Sbjct: 125 FLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAG 184
Query: 280 FMKGAG 285
+G G
Sbjct: 185 LYQGFG 190
Score = 34.7 bits (78), Expect = 0.11
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 219 ASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQ---TLKKGLGEDMYSGITDCARKLWIQE 275
+SF ++G VA +++ AV P++ +K +Q + K+ E Y G+ DC ++ ++
Sbjct: 18 SSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQ 77
Query: 276 GPSAFMKG 283
G +F +G
Sbjct: 78 GFFSFWRG 85
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 100 bits (249), Expect = 2e-21
Identities = 77/270 (28%), Positives = 123/270 (45%), Gaps = 19/270 (7%)
Query: 26 VFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVN-LTLVTPEKAIKLA 84
V+P L +TRLQ Q GK++Y G D +K RA+G G+YRG VN TL++ + +
Sbjct: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCYVTTY 94
Query: 85 ANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSA 144
R + D Q N ++AG A + +T P++++ + L + +G
Sbjct: 95 E---LTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVV------SQHLMMQRKGEK 145
Query: 145 SAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLF 204
R G + +I ++L+ GL G YRG A+LL IP S +++P +
Sbjct: 146 MGRFQVRGNPEGQGVVAFGQTKDIIR-QILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
Query: 205 -ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSG 263
L + VSG +A + A++ P+DV++TR+Q K +
Sbjct: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK-------NS 257
Query: 264 ITDCARKLWIQEGPSAFMKGAGCRALVIAP 293
I R+L +EGP MKG R + P
Sbjct: 258 IILTFRQLMAEEGPWGLMKGLSARIISATP 287
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 97.8 bits (242), Expect = 1e-20
Identities = 77/279 (27%), Positives = 116/279 (41%), Gaps = 28/279 (10%)
Query: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAV 70
+ + G ++G +G+ P D K RLQ Q Y+G++DC++K R E G ++G +
Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQ---TTYRGIVDCMVKIYRHESLLGFFKGMSF 61
Query: 71 NLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKME------MLAGCGAGMCQVVVTCPME 124
+ + ++ +L Q LAGC G Q P +
Sbjct: 62 PIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFD 121
Query: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
++K++LQ+ T GS R A + R +G GL+R
Sbjct: 122 LIKVRLQN---------------QTEPRAQPGSPPP-RYQGPVHCAASIFREEGPRGLFR 165
Query: 185 GLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDV 244
G A LRD P IYF + L + S A V+G AG + VA TPLD+
Sbjct: 166 GAWALTLRDTPTVGIYFITYEGLCR-QYTPEGQNPSSATVLVAGGFAGIASWVAATPLDM 224
Query: 245 LKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
+K+R+Q GL +Y G+ DC QEG F +G
Sbjct: 225 IKSRMQ--MDGLRRRVYQGMLDCMVSSIRQEGLGVFFRG 261
Score = 56.2 bits (134), Expect = 4e-08
Identities = 48/195 (24%), Positives = 73/195 (37%), Gaps = 31/195 (15%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQ--------HGKAMYKGMIDCLMKTARAEGFFGMYR 66
G G + C+ P DL K RLQNQ Y+G + C R EG G++R
Sbjct: 106 GCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFR 165
Query: 67 GAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEML 126
GA TP I + R +G + ++AG AG+ V P++M+
Sbjct: 166 GAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAATPLDMI 225
Query: 127 KIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGL 186
K ++Q G +QG +S +R +GL +RG+
Sbjct: 226 KSRMQMDGLRRRVYQGMLDCMVSS-----------------------IRQEGLGVFFRGV 262
Query: 187 GATLLRDIPFSIIYF 201
R P + + F
Sbjct: 263 TINSARAFPVNAVTF 277
Score = 55.8 bits (133), Expect = 5e-08
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 14/143 (9%)
Query: 172 ELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFAN----LNNLGFNEL-AGKASFAHSFV 226
++ R + L G ++G+ + + + F +++N L E A S+ H F+
Sbjct: 45 KIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFL 104
Query: 227 SGCVAGSIAAVAVTPLDVLKTRIQT-----LKKGLGEDMYSGITDCARKLWIQEGPSAFM 281
+GC G + A + P D++K R+Q + G Y G CA ++ +EGP
Sbjct: 105 AGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLF 164
Query: 282 KGAGCRALVIAPLFGIAQGVYFI 304
+GA L P GI YFI
Sbjct: 165 RGAWALTLRDTPTVGI----YFI 183
Score = 53.1 bits (126), Expect = 3e-07
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 4 QDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQH-GKAMYKGMIDCLMKTARAEGFF 62
Q+ S L+ GG AG+ P+D+ K+R+Q + +Y+GM+DC++ + R EG
Sbjct: 197 QNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLG 256
Query: 63 GMYRGAAVNLTLVTPEKAIKLAANDFFRR 91
+RG +N P A+ + ++ R
Sbjct: 257 VFFRGVTINSARAFPVNAVTFLSYEYLLR 285
Score = 45.1 bits (105), Expect = 8e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA 284
FV+G ++G++ V P D +K R+QT + Y GI DC K++ E F KG
Sbjct: 6 FVAGWISGALGLVLGHPFDTVKVRLQT------QTTYRGIVDCMVKIYRHESLLGFFKGM 59
Query: 285 GCRALVIAPLFGIAQGVY 302
IA + + GVY
Sbjct: 60 SFPIASIAVVNSVLFGVY 77
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 97.4 bits (241), Expect = 1e-20
Identities = 81/300 (27%), Positives = 128/300 (42%), Gaps = 44/300 (14%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHG------KAMYKGMIDCLMKTARAEG 60
S + GGVA V T V PI+ K LQ QH + YKG+IDC+++ + +G
Sbjct: 7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQG 66
Query: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKM------EMLAGCGAGM 114
F +RG N+ P +A+ A D +++L + G+ R+ + + +G AG
Sbjct: 67 FLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL-GGVDRHKQFWRYFAGNLASGGAAGA 125
Query: 115 CQVVVTCPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWEL 173
+ P++ + +L D G+ G+A I ++
Sbjct: 126 TSLCFVYPLDFARTRLAADVGK--------------------GAAQREFHGLGDCII-KI 164
Query: 174 LRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGS 233
++ GL GLY+G ++ I + YF ++ + H FVS +A S
Sbjct: 165 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKG-----MLPDPKNVHIFVSWMIAQS 219
Query: 234 IAAVA---VTPLDVLKTRIQTLKKGLGED-MYSGITDCARKLWIQEGPSAFMKGAGCRAL 289
+ AVA P D ++ R+ G D MY+G DC RK+ EG AF KGA L
Sbjct: 220 VTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVL 279
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 97.1 bits (240), Expect = 2e-20
Identities = 83/284 (29%), Positives = 124/284 (43%), Gaps = 34/284 (11%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQH-GKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLT 73
G G+ GV P D K RLQ Q K Y+G + C + E G+Y+G L
Sbjct: 8 GCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLM 67
Query: 74 LVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK--IQLQ 131
+T A+ R L D + LAG AG Q V+ CPME+ K +QLQ
Sbjct: 68 GLTFINALVFGVQGNTLRALGHDSPLN----QFLAGAAAGAIQCVICCPMELAKTRLQLQ 123
Query: 132 DAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLL 191
DAG +R+Y + S +A ++ +GL G+ RG+ +TLL
Sbjct: 124 DAG--------------PARTY---------KGSLDCLA-QIYGHEGLRGVNRGMVSTLL 159
Query: 192 RDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQT 251
R+ P +YF + L E + ++G +G ++ ++ P+DV+K+R+Q
Sbjct: 160 RETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQA 219
Query: 252 LKKGL-GEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPL 294
GL G Y GI DC + + EG F +G L P+
Sbjct: 220 --DGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPV 261
Score = 61.6 bits (148), Expect = 9e-10
Identities = 52/204 (25%), Positives = 89/204 (43%), Gaps = 35/204 (17%)
Query: 102 LKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTH 161
+ ++ LAGC G+ V+V P + +K++LQ S + G+
Sbjct: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQ--------------VQSVEKPQYRGTLHCF 46
Query: 162 RRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFAN-LNNLGFNELAGKAS 220
+ +++ + + GLY+GLG+ L+ + + F + N L LG + S
Sbjct: 47 K---------SIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHD------S 91
Query: 221 FAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAF 280
+ F++G AG+I V P+++ KTR+Q G Y G DC +++ EG
Sbjct: 92 PLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPAR-TYKGSLDCLAQIYGHEGLRGV 150
Query: 281 MKGAGCRALVIAPLFGIAQGVYFI 304
+G L P F GVYF+
Sbjct: 151 NRGMVSTLLRETPSF----GVYFL 170
Score = 61.2 bits (147), Expect = 1e-09
Identities = 57/195 (29%), Positives = 83/195 (42%), Gaps = 27/195 (13%)
Query: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHG--KAMYKGMIDCLMKTARAEGFFGMYRGA 68
+ + G AG + P++LAKTRLQ Q YKG +DCL + EG G+ RG
Sbjct: 95 QFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGM 154
Query: 69 AVNLTLVTPEKAIKLAANDFFRRLL-MEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK 127
L TP + D R L E G + + +LAG +G+ + T P++++K
Sbjct: 155 VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVK 214
Query: 128 IQLQDAG-RLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGL 186
+LQ G R A ++G +SY R +G RGL
Sbjct: 215 SRLQADGLRGAPRYRGILDC--VHQSY---------------------RAEGWRVFTRGL 251
Query: 187 GATLLRDIPFSIIYF 201
+TLLR P + F
Sbjct: 252 ASTLLRAFPVNAATF 266
Score = 50.8 bits (120), Expect = 2e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 6 LSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ--HGKAMYKGMIDCLMKTARAEGFFG 63
L + L+ GG +G+V +P+D+ K+RLQ G Y+G++DC+ ++ RAEG+
Sbjct: 187 LLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRV 246
Query: 64 MYRGAAVNLTLVTPEKAIKLA 84
RG A L P A A
Sbjct: 247 FTRGLASTLLRAFPVNAATFA 267
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 96.3 bits (238), Expect = 3e-20
Identities = 75/306 (24%), Positives = 132/306 (43%), Gaps = 44/306 (14%)
Query: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM------YKGMIDCLMK 54
MT Q +S + GG+A + T V PI+ K LQ QH YKG++DC+++
Sbjct: 1 MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVR 60
Query: 55 TARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKM------EMLA 108
+ +G +RG N+ P +A+ A D ++++ + G+ ++ + + +
Sbjct: 61 IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKHTQFWRYFAGNLAS 119
Query: 109 GCGAGMCQVVVTCPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSAT 167
G AG + P++ + +L D G+ +G+ R
Sbjct: 120 GGAAGATSLCFVYPLDFARTRLAADVGK-------------------SGTEREFRGLGDC 160
Query: 168 LIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVS 227
L+ ++ ++ G+ GLY+G ++ I + YF ++ + H VS
Sbjct: 161 LV--KITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKG-----MLPDPKNTHIVVS 213
Query: 228 GCVAGSIAAVAVT---PLDVLKTRIQTLKKGLGED-MYSGITDCARKLWIQEGPSAFMKG 283
+A ++ AVA P D ++ R+ G D MY+G DC RK++ EG AF KG
Sbjct: 214 WMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKG 273
Query: 284 AGCRAL 289
A L
Sbjct: 274 AWSNVL 279
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 95.1 bits (235), Expect = 7e-20
Identities = 78/281 (27%), Positives = 122/281 (43%), Gaps = 37/281 (13%)
Query: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM--------YKGMIDCLMKTARAEGFFGM 64
+ GG+A +V FP+DL KTRLQ Q G+++ Y+GM L + + EG +
Sbjct: 45 VYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
Y G A L IK+ +RL +E L + M+ G +G+ + P +
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163
Query: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
+LKI++Q G L QGS ++ + +G GL+R
Sbjct: 164 VLKIRMQAQGSL---FQGSMIGSFI----------------------DIYQQEGTRGLWR 198
Query: 185 GLGATLLRDIPFSIIYFPLF-ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLD 243
G+ T R + P++ +L + + G H FVS G A+A P+D
Sbjct: 199 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTH-FVSSFTCGLAGALASNPVD 257
Query: 244 VLKTRIQTLKKGLGE-DMYSGITDCARKLWIQEGPSAFMKG 283
V++TR+ + +G D+Y G D K+W EG A KG
Sbjct: 258 VVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKG 298
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA----MYKGMIDCLMKTARAEGFF 62
+I ++ GL G P+D+ +TR+ NQ +YKG +D ++K + EGFF
Sbjct: 234 TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFF 293
Query: 63 GMYRGAAVNLTLVTPEKAIKLAANDFFRRL 92
+Y+G N + P I + +RL
Sbjct: 294 ALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
Score = 47.4 bits (111), Expect = 2e-05
Identities = 43/211 (20%), Positives = 87/211 (41%), Gaps = 28/211 (13%)
Query: 4 QDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFG 63
+D ++ +I G V+G++ T P D+ K R+Q Q G MI + + EG G
Sbjct: 137 EDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRG 195
Query: 64 MYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQVVVTCP 122
++RG ++L D ++ L+ GM + + ++ G+ + + P
Sbjct: 196 LWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNP 255
Query: 123 MEMLKIQLQDAGRLAVH---HQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGL 179
+++++ ++ + + H ++G+ L W + +G
Sbjct: 256 VDVVRTRMMNQRAIVGHVDLYKGTV--------------------DGILKMW---KHEGF 292
Query: 180 AGLYRGLGATLLRDIPFSIIYFPLFANLNNL 210
LY+G LR P++II+F + L L
Sbjct: 293 FALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
Score = 29.6 bits (65), Expect = 3.6
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 4/82 (4%)
Query: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLG----EDMYSGITDCARKLWIQEGPSAF 280
FV G +A +A P+D+ KTR+Q + + E Y G+ ++ +EG A
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 281 MKGAGCRALVIAPLFGIAQGVY 302
G L A I G+Y
Sbjct: 104 YSGIAPALLRQASYGTIKIGIY 125
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 95.1 bits (235), Expect = 7e-20
Identities = 78/281 (27%), Positives = 122/281 (43%), Gaps = 37/281 (13%)
Query: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM--------YKGMIDCLMKTARAEGFFGM 64
+ GG+A +V FP+DL KTRLQ Q G+++ Y+GM L + + EG +
Sbjct: 42 VYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
Y G A L IK+ +RL +E L + M+ G +G+ + P +
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 160
Query: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
+LKI++Q G L QGS ++ + +G GL+R
Sbjct: 161 VLKIRMQAQGSL---FQGSMIGSFI----------------------DIYQQEGTRGLWR 195
Query: 185 GLGATLLRDIPFSIIYFPLF-ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLD 243
G+ T R + P++ +L + + G H FVS G A+A P+D
Sbjct: 196 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTH-FVSSFTCGLAGALASNPVD 254
Query: 244 VLKTRIQTLKKGLGE-DMYSGITDCARKLWIQEGPSAFMKG 283
V++TR+ + +G D+Y G D K+W EG A KG
Sbjct: 255 VVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKG 295
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA----MYKGMIDCLMKTARAEGFF 62
+I ++ GL G P+D+ +TR+ NQ +YKG +D ++K + EGFF
Sbjct: 231 TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFF 290
Query: 63 GMYRGAAVNLTLVTPEKAIKLAANDFFRRL 92
+Y+G N + P I + +RL
Sbjct: 291 ALYKGFWPNWLRLGPWNIIFFITYEQLKRL 320
Score = 47.4 bits (111), Expect = 2e-05
Identities = 43/211 (20%), Positives = 87/211 (41%), Gaps = 28/211 (13%)
Query: 4 QDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFG 63
+D ++ +I G V+G++ T P D+ K R+Q Q G MI + + EG G
Sbjct: 134 EDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRG 192
Query: 64 MYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQVVVTCP 122
++RG ++L D ++ L+ GM + + ++ G+ + + P
Sbjct: 193 LWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNP 252
Query: 123 MEMLKIQLQDAGRLAVH---HQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGL 179
+++++ ++ + + H ++G+ L W + +G
Sbjct: 253 VDVVRTRMMNQRAIVGHVDLYKGTV--------------------DGILKMW---KHEGF 289
Query: 180 AGLYRGLGATLLRDIPFSIIYFPLFANLNNL 210
LY+G LR P++II+F + L L
Sbjct: 290 FALYKGFWPNWLRLGPWNIIFFITYEQLKRL 320
Score = 29.6 bits (65), Expect = 3.6
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 4/82 (4%)
Query: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLG----EDMYSGITDCARKLWIQEGPSAF 280
FV G +A +A P+D+ KTR+Q + + E Y G+ ++ +EG A
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 281 MKGAGCRALVIAPLFGIAQGVY 302
G L A I G+Y
Sbjct: 101 YSGIAPALLRQASYGTIKIGIY 122
>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
Length = 308
Score = 92.4 bits (228), Expect = 5e-19
Identities = 78/292 (26%), Positives = 126/292 (43%), Gaps = 20/292 (6%)
Query: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNL 72
+ G + G+ GV +P+D K R+Q + Y G+ C+ T E +G YRG ++ +
Sbjct: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE---PKYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
Query: 73 TLVTPEKAIKLAANDF----FRRLLMEDGMQRNLKMEM-LAGCGAGMCQVVVTCPMEMLK 127
V+ ++ RL + + K ++ L+GC +G+ +V +T P E+ K
Sbjct: 61 CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK 120
Query: 128 IQLQDAGRLAVHHQ-----GSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
++LQ + + G + P +R P L + R +GL GL
Sbjct: 121 VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLAT--VAREEGLCGL 178
Query: 183 YRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPL 242
Y+G A +LRD YF +A L + V+G AG +A TP+
Sbjct: 179 YKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPM 238
Query: 243 DVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA---GCRALVI 291
DV+K+R+Q G G+ Y G+ C +EGP KG CRA +
Sbjct: 239 DVIKSRLQA--DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPV 288
Score = 47.8 bits (112), Expect = 1e-05
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQ-NQHGKAMYKGMIDCLMKTARAEGF 61
H + L+ GG AG++ P+D+ K+RLQ + G+ Y+G++ C++ + R EG
Sbjct: 212 HSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGP 271
Query: 62 FGMYRGAAVNLTLVTPEKAIKLAANDFFRRL 92
+++G +N P + A + RL
Sbjct: 272 RVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 51/217 (23%)
Query: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHG---------------------------KAMY 45
++G +GLV V P ++AK RLQ Q + Y
Sbjct: 100 LSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKY 159
Query: 46 KGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQR-NLKM 104
+G + CL AR EG G+Y+G++ + A + L G R ++
Sbjct: 160 RGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPG 219
Query: 105 EMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRP 164
++AG AG+ V PM+++K +LQ G+ ++G TS
Sbjct: 220 VLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTS-------------- 265
Query: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYF 201
+R +G L++GL R P +++ F
Sbjct: 266 ---------VREEGPRVLFKGLVLNCCRAFPVNMVVF 293
Score = 40.4 bits (93), Expect = 0.002
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA 284
FV+G + G PLD +K RIQT E Y+GI C R + +E F +G
Sbjct: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT------EPKYTGIWHCVRDTYHRERVWGFYRGL 56
Query: 285 GCRALVIAPLFGIAQGVY 302
++ + ++ G Y
Sbjct: 57 SLPVCTVSLVSSVSFGTY 74
>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
Length = 274
Score = 90.9 bits (224), Expect = 1e-18
Identities = 83/301 (27%), Positives = 119/301 (39%), Gaps = 48/301 (15%)
Query: 10 AKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69
A L+ GGVAG+ +FP+D KTRLQ+ G +A GF G+Y G
Sbjct: 8 AALVAGGVAGVSVDLILFPLDTIKTRLQSPQG-------------FNKAGGFHGIYAGVP 54
Query: 70 VNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKME-MLAGCGAGMCQVVVTCPMEMLKI 128
P A ++ + L D M+ MLA + ++ P E++K
Sbjct: 55 SAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVK- 113
Query: 129 QLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGA 188
R+ + S T + I +L +G+ GLYRG +
Sbjct: 114 ---------------------QRAQVSASTRTFQ------IFSNILYEEGIQGLYRGYKS 146
Query: 189 TLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTR 248
T+LR+IPFS++ FPL+ +L L S V G AG AA TPLDV KTR
Sbjct: 147 TVLREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTR 206
Query: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVYFIGIGE 308
I K G + +W +G + G R I+ G F+G +
Sbjct: 207 IMLAKAG-SSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAIS-----LGGFIFLGAYD 260
Query: 309 R 309
R
Sbjct: 261 R 261
Score = 32.0 bits (71), Expect = 0.73
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 8/52 (15%)
Query: 225 FVSGCVAGSIAAVAVT----PLDVLKTRIQT----LKKGLGEDMYSGITDCA 268
FV+ VAG +A V+V PLD +KTR+Q+ K G +Y+G+ A
Sbjct: 6 FVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKAGGFHGIYAGVPSAA 57
Score = 31.6 bits (70), Expect = 0.96
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQ-NQHGKAMYKG-MIDCLMKTARAEGFFGMYRGAAVNL 72
G AG P+D+AKTR+ + G + G ++ L R++G G++ G +
Sbjct: 186 GAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRM 245
Query: 73 TLVTPEKAIKLAANDFFRRLLMEDG 97
++ I L A D LL+E G
Sbjct: 246 AAISLGGFIFLGAYDRTHSLLLEVG 270
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 90.5 bits (223), Expect = 2e-18
Identities = 75/306 (24%), Positives = 128/306 (41%), Gaps = 44/306 (14%)
Query: 1 MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM------YKGMIDCLMK 54
MT +S + GGVA + T V PI+ K LQ QH YKG+IDC+++
Sbjct: 1 MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVR 60
Query: 55 TARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKM------EMLA 108
+ +G +RG N+ P +A+ A D ++++ + G+ + + + +
Sbjct: 61 IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKRTQFWLYFAGNLAS 119
Query: 109 GCGAGMCQVVVTCPMEMLKIQL-QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSAT 167
G AG + P++ + +L D G+ G+ R
Sbjct: 120 GGAAGATSLCFVYPLDFARTRLAADVGK-------------------AGAEREFRGLGDC 160
Query: 168 LIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVS 227
L+ ++ ++ G+ GLY+G ++ I + YF ++ + H +S
Sbjct: 161 LV--KIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKG-----MLPDPKNTHIVIS 213
Query: 228 GCVAGSIAAVA---VTPLDVLKTRIQTLKKGLGED-MYSGITDCARKLWIQEGPSAFMKG 283
+A ++ AVA P D ++ R+ G D MY+G DC RK+ EG AF KG
Sbjct: 214 WMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKG 273
Query: 284 AGCRAL 289
A L
Sbjct: 274 AWSNVL 279
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 88.6 bits (218), Expect = 7e-18
Identities = 85/288 (29%), Positives = 120/288 (41%), Gaps = 37/288 (12%)
Query: 6 LSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA-----MYKGMIDCLMKTARAEG 60
+S L+ GG G+ V P+D K RLQ Q MY G DC KT EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 61 FFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLM---EDGMQRNLKMEMLAGCGAGMCQV 117
G+YRG A + VTP A+ ++L ED + + AG +G+
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVL--SYPQLFAAGMLSGVFTT 125
Query: 118 VVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQ 177
+ P E +K LQ S+ S TG+ A +L +
Sbjct: 126 GIMTPGERIKCLLQ-------------IQASSGESKYTGTLD---------CAKKLYQEF 163
Query: 178 GLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNE--LAGKASFAHSFVSGCVAGSIA 235
G+ G+Y+G TL+RD+P S +YF + L N+ E + S V+G +AG
Sbjct: 164 GIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFN 223
Query: 236 AVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
P DVLK+R QT G +G D R+L EG ++ KG
Sbjct: 224 WAVAIPPDVLKSRFQTAPPG---KYPNGFRDVLRELIRDEGVTSLYKG 268
Score = 62.0 bits (149), Expect = 7e-10
Identities = 53/199 (26%), Positives = 86/199 (43%), Gaps = 24/199 (12%)
Query: 106 MLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPS 165
+LAG G+C V V P++ +K++LQ S P Y+ G+ R+
Sbjct: 14 LLAGGFGGVCLVFVGHPLDTVKVRLQTQ---------PPSLPGQPPMYS-GTFDCFRKT- 62
Query: 166 ATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSF 225
L +G+ GLYRG+ A ++ P + F F L S+ F
Sbjct: 63 --------LFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLF 114
Query: 226 VSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAG 285
+G ++G +TP + +K +Q ++ GE Y+G DCA+KL+ + G KG
Sbjct: 115 AAGMLSGVFTTGIMTPGERIKCLLQ-IQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTV 173
Query: 286 CRALVIAPLFGIAQGVYFI 304
+ P A G+YF+
Sbjct: 174 LTLMRDVP----ASGMYFM 188
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/192 (22%), Positives = 77/192 (40%), Gaps = 29/192 (15%)
Query: 15 GGVAGLVGVTCVFPIDLAKTRLQNQ--HGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNL 72
G ++G+ + P + K LQ Q G++ Y G +DC K + G G+Y+G + L
Sbjct: 117 GMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTL 176
Query: 73 TLVTPEKAIKLAANDFFRRLLMEDGM---QRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQ 129
P + ++ + + +G + + ++AG AG+ V P ++LK +
Sbjct: 177 MRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSR 236
Query: 130 LQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGAT 189
Q A Y G R EL+R +G+ LY+G A
Sbjct: 237 FQTA---------------PPGKYPNGFRDVLR---------ELIRDEGVTSLYKGFNAV 272
Query: 190 LLRDIPFSIIYF 201
++R P + F
Sbjct: 273 MIRAFPANAACF 284
Score = 43.5 bits (101), Expect = 2e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 230 VAGSIAAVAVT----PLDVLKTRIQTLKKGLGED--MYSGITDCARKLWIQEGPSAFMKG 283
+AG V + PLD +K R+QT L MYSG DC RK +EG + +G
Sbjct: 15 LAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRG 74
Query: 284 AGCRALVIAPLFGIAQGVYFIGIGERI 310
+ + P+F + + G+G+++
Sbjct: 75 MAAPIIGVTPMFAVC--FFGFGLGKKL 99
Score = 36.6 bits (83), Expect = 0.030
Identities = 20/63 (31%), Positives = 29/63 (46%)
Query: 5 DLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGM 64
+LS L+ GG+AG+ P D+ K+R Q G D L + R EG +
Sbjct: 206 ELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSL 265
Query: 65 YRG 67
Y+G
Sbjct: 266 YKG 268
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 87.8 bits (216), Expect = 1e-17
Identities = 78/286 (27%), Positives = 122/286 (42%), Gaps = 39/286 (13%)
Query: 23 VTCVF--PIDLAKTRLQNQHGKAM--------YKGMIDCLMKTARAEGFFGMYRGAAVNL 72
+ CVF P+++ KTRLQ Q G+ Y G I + ARA+G +G+ +G A L
Sbjct: 19 LACVFTNPLEVVKTRLQLQ-GELQARGTYPRPYHGFIASVAAVARADGLWGLQKGLAAGL 77
Query: 73 TLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQ- 131
++ + L + G+ + ++AG AG V P ++K QLQ
Sbjct: 78 LYQGLMNGVRF----YCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQA 133
Query: 132 -DAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATL 190
+AV HQ H + + R QGL GL++G+G +
Sbjct: 134 QTVAAVAVGHQ-------------------HNHQTVLGALETIWRQQGLLGLWQGVGGAV 174
Query: 191 LRDIPFSIIYFPLFANLNN-LGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRI 249
R + S FA+ + + + S+ + G ++ V +TP DV+ TR+
Sbjct: 175 PRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRL 234
Query: 250 --QTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAP 293
Q + +Y G+TDC K+W QEGP A KG G L + P
Sbjct: 235 YNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGP 280
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQH----GKA-MYKGMIDCLMKTARAEGFFGMYR 66
L G ++ + V + P D+ TRL NQ G+ +Y G+ DC++K R EG +Y+
Sbjct: 210 LAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYK 269
Query: 67 GAAVNLTLVTPEKAIKLAANDFFRRL 92
G + P + + D R+L
Sbjct: 270 GLGPAYLRLGPHTILSMLFWDELRKL 295
Score = 33.9 bits (76), Expect = 0.19
Identities = 48/217 (22%), Positives = 85/217 (39%), Gaps = 33/217 (15%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKG-------MIDCLMKTARAEGFFGM 64
++ G VAG +G P L KT+LQ Q A+ G ++ L R +G G+
Sbjct: 107 VVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGL 166
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGM--QRNLKMEMLAGCGAGMCQVVVTCP 122
++G + V A +LA + + + + + + + G + + VVV P
Sbjct: 167 WQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTP 226
Query: 123 MEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
+++ +L + + R G T ++ R +G L
Sbjct: 227 FDVVSTRLY-----------NQPVDTAGRGQLYG--------GLTDCMVKIWRQEGPLAL 267
Query: 183 YRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKA 219
Y+GLG LR P +I+ + L +LAG+A
Sbjct: 268 YKGLGPAYLRLGPHTILSMLFWDEL-----RKLAGRA 299
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 87.0 bits (214), Expect = 2e-17
Identities = 73/287 (25%), Positives = 118/287 (41%), Gaps = 33/287 (11%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGK--------AMYKGMIDCLMKTARA 58
++ K + G A FP+D AK RLQ Q Y+G++ ++ R
Sbjct: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
Query: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQV 117
EG Y G L +I++ D +++ G + L +LAGC G V
Sbjct: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
Query: 118 VVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELL-RT 176
P +++K++ Q + L G + + R+ S T+ A+ + R
Sbjct: 132 TCAQPTDVVKVRFQASIHL-------------------GPSRSDRKYSGTMDAYRTIARE 172
Query: 177 QGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAA 236
+G+ GL++G ++R+ + + L + +F FVS AG A
Sbjct: 173 EGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCAT 232
Query: 237 VAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
V +P+DV+KTR G Y DC K+ QEGP+AF KG
Sbjct: 233 VVASPVDVVKTRYMNSPPG----QYFSPLDCMIKMVAQEGPTAFYKG 275
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 87.0 bits (214), Expect = 2e-17
Identities = 73/287 (25%), Positives = 118/287 (41%), Gaps = 33/287 (11%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGK--------AMYKGMIDCLMKTARA 58
++ K + G A FP+D AK RLQ Q Y+G++ ++ R
Sbjct: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
Query: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQV 117
EG Y G L +I++ D +++ G + L +LAGC G V
Sbjct: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
Query: 118 VVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELL-RT 176
P +++K++ Q + L G + + R+ S T+ A+ + R
Sbjct: 132 TCAQPTDVVKVRFQASIHL-------------------GPSRSDRKYSGTMDAYRTIARE 172
Query: 177 QGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAA 236
+G+ GL++G ++R+ + + L + +F FVS AG A
Sbjct: 173 EGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCAT 232
Query: 237 VAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
V +P+DV+KTR G Y DC K+ QEGP+AF KG
Sbjct: 233 VVASPVDVVKTRYMNSPPG----QYFSPLDCMIKMVAQEGPTAFYKG 275
Score = 35.0 bits (79), Expect = 0.087
Identities = 21/83 (25%), Positives = 33/83 (39%), Gaps = 1/83 (1%)
Query: 18 AGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTP 77
AG P+D+ KTR N Y +DC++K EG Y+G + +
Sbjct: 227 AGFCATVVASPVDVVKTRYMNSP-PGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGS 285
Query: 78 EKAIKLAANDFFRRLLMEDGMQR 100
+ + +R LM+ M R
Sbjct: 286 WNVVMFVTYEQLKRALMKVQMLR 308
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 86.3 bits (212), Expect = 3e-17
Identities = 79/305 (25%), Positives = 128/305 (41%), Gaps = 38/305 (12%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGK--AMYKGMIDCLMKTARAEGFFGM 64
++T ++ G VAG++ ++PID KTR+Q+ A Y+ +++ L + R EG +
Sbjct: 71 TVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRP 130
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLME---DGMQRNLKMEMLAGCGAGMCQVVVTC 121
RG V T P A+ A + ++ L + G ++ AGC A +
Sbjct: 131 MRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIA-NGAAGCVATLLHDAAMN 189
Query: 122 PMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAG 181
P E++K ++Q ++ HR W+ +G
Sbjct: 190 PAEVVKQRMQ-----------------------MYNSPYHRVTDCVRAVWQ---NEGAGA 223
Query: 182 LYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTP 241
YR L ++PF I+F + L FN +H +SG AG++AA A TP
Sbjct: 224 FYRSYTTQLTMNVPFQAIHFMTYEFLQE-HFNPQRRYNPSSH-VLSGACAGAVAAAATTP 281
Query: 242 LDVLKTRIQTLKK-GLGEDMYSGITDCA---RKLWIQEGPSAFMKGAGCRALVIAPLFGI 297
LDV KT + T + L + IT A R ++ G +A+ +G R + P I
Sbjct: 282 LDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAI 341
Query: 298 AQGVY 302
A VY
Sbjct: 342 AWSVY 346
Score = 60.1 bits (144), Expect = 3e-09
Identities = 51/200 (25%), Positives = 84/200 (42%), Gaps = 32/200 (16%)
Query: 106 MLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPS 165
M+AG AG+ + V P++ +K ++Q S A+ +R
Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQ--------------------SLQPDPAARYRNVL 115
Query: 166 ATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNEL-AGKASFAHS 224
L W ++RT+GL RGL T P +YF + L + + G S +
Sbjct: 116 EAL--WRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIAN 173
Query: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA 284
+GCVA + A+ P +V+K R+Q + Y +TDC R +W EG AF +
Sbjct: 174 GAAGCVATLLHDAAMNPAEVVKQRMQ-----MYNSPYHRVTDCVRAVWQNEGAGAFYRSY 228
Query: 285 GCRALVIAPLFGIAQGVYFI 304
+ + P Q ++F+
Sbjct: 229 TTQLTMNVPF----QAIHFM 244
Score = 37.0 bits (84), Expect = 0.023
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 7/92 (7%)
Query: 9 TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYK-------GMIDCLMKTARAEGF 61
++ +++G AG V P+D+ KT L Q A+ GM + G
Sbjct: 262 SSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGV 321
Query: 62 FGMYRGAAVNLTLVTPEKAIKLAANDFFRRLL 93
+RG + P AI + +FF+ L+
Sbjct: 322 TAYFRGVQARVIYQIPSTAIAWSVYEFFKYLI 353
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 5/92 (5%)
Query: 212 FNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKL 271
+ L A+ V+G VAG + + P+D +KTR+Q+L+ Y + + ++
Sbjct: 63 YEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAA-RYRNVLEALWRI 121
Query: 272 WIQEGPSAFMKGAGCRALVIAPLFGIAQGVYF 303
EG M+G A P A +YF
Sbjct: 122 IRTEGLWRPMRGLNVTATGAGP----AHALYF 149
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 85.9 bits (211), Expect = 4e-17
Identities = 72/282 (25%), Positives = 121/282 (42%), Gaps = 38/282 (13%)
Query: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQ-------HGKAMYKGMIDCLMKTARAEGFFGMY 65
+ GG+A + FPIDL KTRLQ Q + Y+GM+ L++ R EG +Y
Sbjct: 10 VYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALY 69
Query: 66 RGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEM 125
G A + IK+ +RL +E L + ++ G +G+ + P ++
Sbjct: 70 SGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDV 129
Query: 126 LKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRG 185
LKI++Q + +T + G+ + + +G GL++G
Sbjct: 130 LKIRMQ-------------AQSNTIQGGMIGN------------FMNIYQQEGTRGLWKG 164
Query: 186 LGATLLRDIPFSIIYFPLF-ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDV 244
+ T R + P++ +L + L G + H F+S G A+A P+DV
Sbjct: 165 VSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTH-FLSSFTCGLAGALASNPVDV 223
Query: 245 LKTRI---QTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
++TR+ + L+ G Y+G DC + W EG A KG
Sbjct: 224 VRTRMMNQRVLRDGRCSG-YTGTLDCLLQTWKNEGFFALYKG 264
Score = 48.9 bits (115), Expect = 6e-06
Identities = 45/208 (21%), Positives = 90/208 (43%), Gaps = 21/208 (10%)
Query: 4 QDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFG 63
+D ++ +I G ++G++ T P D+ K R+Q Q + GMI M + EG G
Sbjct: 102 EDETLPINVICGILSGVISSTIANPTDVLKIRMQAQ-SNTIQGGMIGNFMNIYQQEGTRG 160
Query: 64 MYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQVVVTCP 122
+++G ++ ++L D ++ L+ G+ + + L+ G+ + + P
Sbjct: 161 LWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNP 220
Query: 123 MEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
+++++ ++ + V G S TG+ L W + +G L
Sbjct: 221 VDVVRTRMMNQ---RVLRDGRCSG-------YTGTLD------CLLQTW---KNEGFFAL 261
Query: 183 YRGLGATLLRDIPFSIIYFPLFANLNNL 210
Y+G LR P++II+F + L L
Sbjct: 262 YKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 5/130 (3%)
Query: 175 RTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSI 234
R +GL LY G+ +LR + I + +L L F E + + + G ++G I
Sbjct: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRL-FIERPEDETLPINVICGILSGVI 119
Query: 235 AAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPL 294
++ P DVLK R+Q + M + ++ QEG KG A A +
Sbjct: 120 SSTIANPTDVLKIRMQAQSNTIQGGMIGNFMN----IYQQEGTRGLWKGVSLTAQRAAIV 175
Query: 295 FGIAQGVYFI 304
G+ VY I
Sbjct: 176 VGVELPVYDI 185
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 85.9 bits (211), Expect = 4e-17
Identities = 74/292 (25%), Positives = 128/292 (43%), Gaps = 29/292 (9%)
Query: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAV 70
+L+ G+AG + ++ P++LA Q + +G + RAEG +++G AV
Sbjct: 15 RLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAV 74
Query: 71 NLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQL 130
+ P A++LAA F L +D + ++AG AGM +VT P +++K +L
Sbjct: 75 ACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRL 134
Query: 131 QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATL 190
L ++G A ST + + +G LYRG+ T+
Sbjct: 135 IMQNILEPSYRGLLHAFST-----------------------IYQQEGFLALYRGVSLTV 171
Query: 191 LRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQ 250
+ +PFS ++ NL + +N + S +F + C+A ++ P + +K ++Q
Sbjct: 172 VGALPFSAGSLLVYMNLEKI-WNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQ 230
Query: 251 TLKKGL----GEDM-YSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGI 297
L G D+ +SG DC R++ +G G L I P FGI
Sbjct: 231 AQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGI 282
Score = 62.4 bits (150), Expect = 5e-10
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 17/200 (8%)
Query: 6 LSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHG-KAMYKGMIDCLMKTARAEGFFGM 64
+S + ++ G +AG+V +P DL KTRL Q+ + Y+G++ + EGF +
Sbjct: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLAL 163
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
YRG ++ + P A L ++ Q +L C A ++ P E
Sbjct: 164 YRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFE 223
Query: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
+K ++Q A + H G + +G+ R ++++ QG+ GL+
Sbjct: 224 TVKRKMQ-AQSPYLPHSGGVDV------HFSGAVDCFR---------QIVKAQGVLGLWN 267
Query: 185 GLGATLLRDIPFSIIYFPLF 204
GL A LL+ +P+ I F F
Sbjct: 268 GLTANLLKIVPYFGIMFSTF 287
Score = 42.4 bits (98), Expect = 5e-04
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ-----HGKAM---YKGMIDCLMKTARA 58
S+ N +A V T FP + K ++Q Q H + + G +DC + +A
Sbjct: 200 SLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKA 259
Query: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLM 94
+G G++ G NL + P I + +F +R+ +
Sbjct: 260 QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 85.5 bits (210), Expect = 6e-17
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 33/303 (10%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQN--QHGKAMYKGMIDCLMKTARAEGFFGM 64
S++ + G +AG++ + ++P+D KTR+Q+ KA Y + L K R EGF+
Sbjct: 44 SVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRP 103
Query: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
RG V + P A+ A + +R L D + G M ++ M
Sbjct: 104 LRGVNVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMN 162
Query: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
++ Q RL +++ SA S R+ W RT+GL YR
Sbjct: 163 PAEVVKQ---RLQMYNSQHRSAISCIRT-----------------VW---RTEGLGAFYR 199
Query: 185 GLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDV 244
L +IPF I+F + L N +H +SG +AG++AA A TPLDV
Sbjct: 200 SYTTQLTMNIPFQSIHFITYEFLQEQ-VNPHRTYNPQSH-IISGGLAGALAAAATTPLDV 257
Query: 245 LKTRIQT-----LKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQ 299
KT + T L SG+ + R ++ G + + KG R + P I+
Sbjct: 258 CKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISW 317
Query: 300 GVY 302
VY
Sbjct: 318 SVY 320
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 19/202 (9%)
Query: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFF 62
HQ S A I G +A L+ + P ++ K RLQ + + ++ I C+ R EG
Sbjct: 138 HQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYN--SQHRSAISCIRTVWRTEGLG 195
Query: 63 GMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCP 122
YR LT+ P ++I +F + + N + +++G AG T P
Sbjct: 196 AFYRSYTTQLTMNIPFQSIHFITYEFLQE-QVNPHRTYNPQSHIISGGLAGALAAAATTP 254
Query: 123 MEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
+++ K L +A+ + + +G A+ R + + GLAG
Sbjct: 255 LDVCKTLLNTQENVAL-------SLANISGRLSGMANAFR---------TVYQLNGLAGY 298
Query: 183 YRGLGATLLRDIPFSIIYFPLF 204
++G+ A ++ +P + I + ++
Sbjct: 299 FKGIQARVIYQMPSTAISWSVY 320
Score = 42.7 bits (99), Expect = 4e-04
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 8/99 (8%)
Query: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAM--------YKGMIDCLMK 54
H+ + + +I+GG+AG + P+D+ KT L Q A+ GM +
Sbjct: 229 HRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRT 288
Query: 55 TARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLL 93
+ G G ++G + P AI + +FF+ L
Sbjct: 289 VYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
Query: 212 FNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKL 271
+ L AS + +G +AG + + P+D +KTR+Q+L + Y+ I +K+
Sbjct: 36 YENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPD-PKAQYTSIYGALKKI 94
Query: 272 WIQEGPSAFMKGAGCRALVIAPLFGIAQGVYF 303
EG ++G + P A +YF
Sbjct: 95 MRTEGFWRPLRGVNVMIMGAGP----AHAMYF 122
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 85.1 bits (209), Expect = 7e-17
Identities = 69/262 (26%), Positives = 112/262 (42%), Gaps = 35/262 (13%)
Query: 2 THQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGF 61
T +D + GG+AG T V P+D K LQ + + G+ L + EGF
Sbjct: 30 TRRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGF 89
Query: 62 FGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTC 121
G+Y+G + + P AI+ A + ++ L+ ++AG AGM V+ T
Sbjct: 90 LGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTY 149
Query: 122 PMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAG 181
P++M+++ RLA +G S ++ T A + G G
Sbjct: 150 PLDMVRV------RLAFQVKGEHSYTGIIHAFKTIYA----------------KEGGFFG 187
Query: 182 LYRGLGATLLRDIPFSIIYFPLFANLNNLGFNE---LAGKASFAH----------SFVSG 228
YRGL T+L P++ + F F L ++G + L G+ S + + + G
Sbjct: 188 FYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCG 247
Query: 229 CVAGSIAAVAVTPLDVLKTRIQ 250
VAG+IA P DV + R+Q
Sbjct: 248 GVAGAIAQTISYPFDVTRRRMQ 269
Score = 65.1 bits (157), Expect = 8e-11
Identities = 52/193 (26%), Positives = 83/193 (43%), Gaps = 28/193 (14%)
Query: 107 LAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSA 166
LAG AG C P++ +K+ LQ HH S R+
Sbjct: 41 LAGGIAGCCAKTTVAPLDRVKVLLQAHN----HHYKHLGVFSALRAVP------------ 84
Query: 167 TLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFV 226
+ +G GLY+G GA ++R P+ I F F + L +L G + H +
Sbjct: 85 --------QKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKL-GISGHVHRLM 135
Query: 227 SGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGP-SAFMKGAG 285
+G +AG A + PLD+++ R+ K GE Y+GI + ++ +EG F +G
Sbjct: 136 AGSMAGMTAVICTYPLDMVRVRLAFQVK--GEHSYTGIIHAFKTIYAKEGGFFGFYRGLM 193
Query: 286 CRALVIAPLFGIA 298
L +AP G++
Sbjct: 194 PTILGMAPYAGVS 206
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 82.4 bits (202), Expect = 5e-16
Identities = 68/284 (23%), Positives = 110/284 (38%), Gaps = 34/284 (11%)
Query: 9 TAKLINGGVAGLVGVTCVFPIDLAKTRLQNQH---------GKAMYKGMIDCLMKTARAE 59
T K + G A + FP+D AK RLQ Q A Y+G++ ++ R E
Sbjct: 14 TVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTE 73
Query: 60 GFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVV 119
G +Y G L ++++ D ++ + ++ +LAG G V V
Sbjct: 74 GPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAV 133
Query: 120 TCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGL 179
P +++K++ Q R G ST +Y T + R +G
Sbjct: 134 AQPTDVVKVRFQAQARAG----GGRRYQSTVNAYKT-----------------IAREEGF 172
Query: 180 AGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAV 239
GL++G + R+ + + + + F S AG V
Sbjct: 173 RGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIA 232
Query: 240 TPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
+P+DV+KTR + LG+ YS CA + +EGP AF KG
Sbjct: 233 SPVDVVKTRY--MNSALGQ--YSSAGHCALTMLQKEGPRAFYKG 272
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 82.4 bits (202), Expect = 5e-16
Identities = 70/283 (24%), Positives = 117/283 (41%), Gaps = 30/283 (10%)
Query: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ-----HGKAMYKGMIDCLMKTARAEGF 61
++ +L + G+A + FP+D AK RLQ Q YKG++ + + EG
Sbjct: 12 TLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGR 71
Query: 62 FGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQR-NLKMEMLAGCGAGMCQVVVT 120
+Y G L ++++ D + L +L ++LAG G V +
Sbjct: 72 MKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIG 131
Query: 121 CPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLA 180
P E++K++LQ L + TG+ + +R +IA T+GL
Sbjct: 132 QPTEVVKVRLQAQSHL-----------HGIKPRYTGTYNAYR-----IIA----TTEGLT 171
Query: 181 GLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVT 240
GL++G L+R + + + + VS +AG A +
Sbjct: 172 GLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSS 231
Query: 241 PLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
P+DV+KTR G Y + +CA K++ EGP+AF KG
Sbjct: 232 PVDVVKTRFINSPPG----QYKSVPNCAMKVFTNEGPTAFFKG 270
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 79.3 bits (194), Expect = 4e-15
Identities = 72/294 (24%), Positives = 122/294 (41%), Gaps = 29/294 (9%)
Query: 12 LINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVN 71
L+ GG AG V TC P+D K +Q ++ G++ + R G ++RG +N
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 249
Query: 72 LTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQ 131
+ + PE AIK A + +RL+ D + ++AG AG PME+LK
Sbjct: 250 VLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKT--- 306
Query: 132 DAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLL 191
R+A+ G S G RR +L +G+A Y+G +L
Sbjct: 307 ---RMALRKTGQYS----------GMLDCARR---------ILAREGVAAFYKGYVPNML 344
Query: 192 RDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFV---SGCVAGSIAAVAVTPLDVLKTR 248
IP++ I ++ L N A ++ FV G ++ + +A PL +++TR
Sbjct: 345 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 404
Query: 249 IQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVY 302
+Q G + ++ + + EG +G + + P I+ VY
Sbjct: 405 MQAQASIEGAPEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVY 457
Score = 68.2 bits (165), Expect = 9e-12
Identities = 49/210 (23%), Positives = 92/210 (43%), Gaps = 31/210 (14%)
Query: 4 QDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFG 63
+ L I +L+ G +AG + + ++P+++ KTR+ + Y GM+DC + EG
Sbjct: 276 ETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAA 334
Query: 64 MYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLK--MEMLAGCG--AGMCQVVV 119
Y+G N+ + P I LA + + ++ + + +L CG + C +
Sbjct: 335 FYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLA 394
Query: 120 TCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAW--ELLRTQ 177
+ P+ +++ ++Q AS P T+ + +LRT+
Sbjct: 395 SYPLALVRTRMQ------------------------AQASIEGAPEVTMSSLFKHILRTE 430
Query: 178 GLAGLYRGLGATLLRDIPFSIIYFPLFANL 207
G GLYRGL ++ IP I + ++ NL
Sbjct: 431 GAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,631,113
Number of Sequences: 37866
Number of extensions: 424509
Number of successful extensions: 1825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1154
Number of HSP's gapped (non-prelim): 258
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.