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Search of human proteins with 138175817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|138175817 zinc finger protein 236 [Homo sapiens]
(1845 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|138175817 zinc finger protein 236 [Homo sapiens] 3779 0.0
gi|118600985 zinc finger protein 91 [Homo sapiens] 358 2e-98
gi|62243640 zinc finger protein 107 [Homo sapiens] 295 4e-79
gi|7706775 zinc finger protein 107 [Homo sapiens] 295 4e-79
gi|156547246 zinc finger protein 160 [Homo sapiens] 291 5e-78
gi|38788302 zinc finger protein 160 [Homo sapiens] 291 5e-78
gi|38788288 zinc finger protein 160 [Homo sapiens] 291 5e-78
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor... 267 6e-71
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor... 267 6e-71
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor... 267 6e-71
gi|188497655 zinc finger protein 84 [Homo sapiens] 267 6e-71
gi|188497653 zinc finger protein 84 [Homo sapiens] 267 6e-71
gi|68303809 zinc finger protein 43 [Homo sapiens] 261 4e-69
gi|222831664 zinc finger protein 184 [Homo sapiens] 254 4e-67
gi|55742736 zinc finger protein 700 [Homo sapiens] 251 4e-66
gi|38570117 zinc finger protein 569 [Homo sapiens] 245 3e-64
gi|32698886 zinc finger protein 595 [Homo sapiens] 242 2e-63
gi|57165428 zinc finger protein 28 [Homo sapiens] 236 2e-61
gi|122937229 zinc finger protein 629 [Homo sapiens] 229 2e-59
gi|74027276 zinc finger protein 226 isoform a [Homo sapiens] 228 3e-59
gi|74027274 zinc finger protein 226 isoform a [Homo sapiens] 228 3e-59
gi|32698786 zinc finger protein 227 [Homo sapiens] 223 2e-57
gi|138175847 zinc finger protein 228 isoform 1 [Homo sapiens] 221 4e-57
gi|138175821 zinc finger protein 228 isoform 2 [Homo sapiens] 221 4e-57
gi|153792259 zinc finger protein 778 [Homo sapiens] 219 3e-56
gi|116256455 zinc finger protein 429 [Homo sapiens] 218 4e-56
gi|223468695 zinc finger protein 572 [Homo sapiens] 214 6e-55
gi|148596977 zinc finger protein 31 [Homo sapiens] 211 7e-54
gi|113680890 zinc finger protein 90 [Homo sapiens] 210 1e-53
gi|169790765 zinc finger protein 85 [Homo sapiens] 210 1e-53
>gi|138175817 zinc finger protein 236 [Homo sapiens]
Length = 1845
Score = 3779 bits (9801), Expect = 0.0
Identities = 1845/1845 (100%), Positives = 1845/1845 (100%)
Query: 1 MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHE 60
MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHE
Sbjct: 1 MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHE 60
Query: 61 RNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEEN 120
RNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEEN
Sbjct: 61 RNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEEN 120
Query: 121 LICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV 180
LICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV
Sbjct: 121 LICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV 180
Query: 181 SSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGAL 240
SSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGAL
Sbjct: 181 SSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGAL 240
Query: 241 QTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSL 300
QTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSL
Sbjct: 241 QTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSL 300
Query: 301 NTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQ 360
NTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQ
Sbjct: 301 NTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQ 360
Query: 361 LLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420
LLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS
Sbjct: 361 LLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420
Query: 421 APHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVR 480
APHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVR
Sbjct: 421 APHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVR 480
Query: 481 WHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC 540
WHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC
Sbjct: 481 WHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC 540
Query: 541 QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQ 600
QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQ
Sbjct: 541 QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQ 600
Query: 601 RKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCF 660
RKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCF
Sbjct: 601 RKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCF 660
Query: 661 YCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNG 720
YCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNG
Sbjct: 661 YCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNG 720
Query: 721 AFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI 780
AFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI
Sbjct: 721 AFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI 780
Query: 781 DDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLA 840
DDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLA
Sbjct: 781 DDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLA 840
Query: 841 DQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQ 900
DQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQ
Sbjct: 841 DQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQ 900
Query: 901 QLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNE 960
QLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNE
Sbjct: 901 QLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNE 960
Query: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV
Sbjct: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
Query: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV
Sbjct: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
Query: 1081 SATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
SATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV
Sbjct: 1081 SATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
Query: 1141 QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC
Sbjct: 1141 QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF
Sbjct: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
Query: 1261 RTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQF 1320
RTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQF
Sbjct: 1261 RTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQF 1320
Query: 1321 DQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDA 1380
DQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDA
Sbjct: 1321 DQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDA 1380
Query: 1381 ASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISG 1440
ASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISG
Sbjct: 1381 ASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISG 1440
Query: 1441 LSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNS 1500
LSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNS
Sbjct: 1441 LSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNS 1500
Query: 1501 SLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSG 1560
SLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSG
Sbjct: 1501 SLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSG 1560
Query: 1561 VGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVS 1620
VGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVS
Sbjct: 1561 VGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVS 1620
Query: 1621 HTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVH 1680
HTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVH
Sbjct: 1621 HTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVH 1680
Query: 1681 GRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERH 1740
GRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERH
Sbjct: 1681 GRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERH 1740
Query: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRA 1800
SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRA
Sbjct: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRA 1800
Query: 1801 HSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAAGEWQALTHVF 1845
HSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAAGEWQALTHVF
Sbjct: 1801 HSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAAGEWQALTHVF 1845
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 358 bits (920), Expect = 2e-98
Identities = 277/1039 (26%), Positives = 416/1039 (40%), Gaps = 150/1039 (14%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + S H + +K ++C++C + F LT HK H+GE P C
Sbjct: 238 YKCEECGKAFKQLSTLTTHKIICAK-EKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKC 296
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS ++L H +H E+ C ECG F+ S LA H H G + + C
Sbjct: 297 EECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIH----TGEKPYKC 352
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
K C K F SS L H TH + + Y C C K F++ S LT+H
Sbjct: 353 KECGKAFSNSSTLANHKITHTEEK----------------PYKCKECDKAFKRLSTLTKH 396
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
IH GE+ +KC ECGKAFN+ L H HTGEKP+ C C AF+ +L H +R
Sbjct: 397 KIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKH-KRF 455
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
H+ K + C EC F +L H ++H G A ++TL
Sbjct: 456 HTREK---PFKCKECGKAFIWSSTLTRH-KRIHTGEKPYKCEECGKAFRQSSTL------ 505
Query: 336 QQTEAQATSASSQPSS-QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
T+ + +P + +Q L L++ + S + P ++
Sbjct: 506 --TKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECG----------- 552
Query: 395 QALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
+A + + H + A N SS+S + T + K +E +
Sbjct: 553 KAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHS-SSLSTHKIIHTGEKSYKCEECGKAF 611
Query: 455 D-----KKEKKMIKKKSPF--------------LPGSIREENGVRWHVCPYCAKEFRKPS 495
++ K++ + P+ L R G + + C C K F S
Sbjct: 612 LWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSS 671
Query: 496 DLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKV 555
L H HT EKP+KC +C + F STLT H H G K +KC+ C K+F+ S +L +
Sbjct: 672 TLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTI 731
Query: 556 HIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIP 614
H +HTG +P+ C C K F S H +++ + KP K + GK I
Sbjct: 732 HKFIHTGEKPYKCEECGKAFNWSSSLTKH----------KRIHTREKPFKCKECGKAFI- 780
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQ 674
+ + + ++ ++PYKC C +A+ +S L +
Sbjct: 781 -------------------------WSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTK 815
Query: 675 HIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGI 734
H HTGEKP+KC +CG+ F + L H H G K +KC C AF +L H I
Sbjct: 816 HKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKII 875
Query: 735 HNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQAST 794
H +P C K F S +H + H E + ++ +A S Q +T
Sbjct: 876 HTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFS--------QPSHLTT 927
Query: 795 QMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDG-FVA 853
+ + + E P E L ++ T E +P + +E G
Sbjct: 928 HKR--MHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGE---------KPYKCEECGKAFR 976
Query: 854 PQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQAL 913
L H + P E G + T T H + + +
Sbjct: 977 KSSTLTEHKIIHTGEKP--YKCEECGKAFSQSSTLTRH-------TRMHTGEKPYKCEEC 1027
Query: 914 STSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNE-------DQSRRS 966
+F++ S L TT I + ++ + G F+ + +
Sbjct: 1028 GKAFNRSSKL----------TTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIHTREKP 1077
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C+ C K F +SS L +H R HTGEKPYKC CG+ F S L H+ HTG K + C
Sbjct: 1078 YKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKPYKCE 1137
Query: 1027 VCNASFTTNGSLTRHMATH 1045
C +F + LT H H
Sbjct: 1138 KCGKAFNQSSILTNHKKIH 1156
Score = 291 bits (745), Expect = 4e-78
Identities = 210/704 (29%), Positives = 307/704 (43%), Gaps = 92/704 (13%)
Query: 20 LTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEF 79
LTLN ++ + P +KC+ C +F + S H H K ++C++C + FN
Sbjct: 531 LTLNKHKIIHSREKP--YKCKECGKAFKQFSTLTTHKIIHA-GKKLYKCEECGKAFNHSS 587
Query: 80 NLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAV 138
+L+ HK H+GE C C K F ++L+ H +H E+ C ECG F+ S LA
Sbjct: 588 SLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAK 647
Query: 139 HMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYS 198
H H G + + CK C K F SS L H TH + + Y
Sbjct: 648 HKRIH----TGEKPYKCKECGKAFSNSSTLANHKITHTEEK----------------PYK 687
Query: 199 CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFC 258
C C KTF++ S LT+H IH GE+ +KC ECGKAFN+ L H HTGEKP+ C C
Sbjct: 688 CKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEEC 747
Query: 259 PAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG-------- 310
AF+ +L H +R+H+ K + C EC F +L H ++H G
Sbjct: 748 GKAFNWSSSLTKH-KRIHTREK---PFKCKECGKAFIWSSTLTRH-KRIHTGEKPYKCEE 802
Query: 311 -GPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAP 369
G S SST T H T + ++ +A SS + + ++L + E
Sbjct: 803 CGKAFSRSSTLTKHKTIHTGEKPYKCKEC-GKAFKHSSALAKHKIIHAGEKLYKCEECGK 861
Query: 370 VESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDV 429
+ S ++ T + + + + + S H KT
Sbjct: 862 AFNQSSNLTTHKIIHTK--EKPSKSEECDKAFIWSSTLTEHKRIHTREKTYK-------C 912
Query: 430 SSVSNEQTDPTDAEQEKEQESPEKLDKKEK--KMIKKKSPFLPGSIREENGVRWHVCPYC 487
+ P+ K + EK K E+ K + S I G + + C C
Sbjct: 913 EECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIH-TGEKPYKCEEC 971
Query: 488 AKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSF 547
K FRK S L H IHT EKP+KC +C +AF+ STLT H + HTG K +KC+ C K+F
Sbjct: 972 GKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAF 1031
Query: 548 STSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV- 606
+ S L H +HTG +P+ C C K F +S H +++ + KP K
Sbjct: 1032 NRSSKLTTHKIIHTGEKPYKCEECGKAFISSSTLNGH----------KRIHTREKPYKCE 1081
Query: 607 RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQS--YFNNNFVNEADRPYKCFYCHR 664
GK F QS + ++ ++PYKC C +
Sbjct: 1082 ECGKA----------------------------FSQSSTLTRHKRLHTGEKPYKCGECGK 1113
Query: 665 AYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHT 708
A+K+S L +H HTGEKP+KC +CG+ F + +L H + HT
Sbjct: 1114 AFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIHT 1157
Score = 213 bits (543), Expect = 1e-54
Identities = 184/687 (26%), Positives = 279/687 (40%), Gaps = 105/687 (15%)
Query: 107 SLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK----ACKKEF 162
++K H M+ E IC +F + ME+ Q++ + C +K
Sbjct: 73 NMKQHEMVDEPTG--ICPHFPQDFWPEQS----MEDSFQKVLLRKYEKCGHENLQLRKGC 126
Query: 163 ETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGE 222
++ E K H + + K+ T + ++ + C K F K RH HTG+
Sbjct: 127 KSVDECKVHKEGYNKLNQCLTTAQSK-------VFQCGKYLKVFYKFLNSNRHTIRHTGK 179
Query: 223 RPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNG 282
+ FKC +C K+F + H + EK C C F L +H + +H+E K
Sbjct: 180 KCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNH-KEIHTEDK-- 236
Query: 283 PTYNCTECSCVFKSLGSLNTH--------ISKMHMGGPQNSTSSTETAHVLTATLFQTLP 334
Y C EC FK L +L TH I K G SST T H T +
Sbjct: 237 -PYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYK 295
Query: 335 LQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
++ +A S SS L++ + +G+ P ++
Sbjct: 296 CEEC-GKAFSHSST---------------LAKHKRIHTGEKPYKCEECG----------- 328
Query: 395 QALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
+A S + H + + A + + S+++N + T+ + K +E +K
Sbjct: 329 KAFSRSSTLAKHKRIHTGEKPYKCKECGKAFS-NSSTLANHKITHTEEKPYKCKEC-DKA 386
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
K+ + K K G + + C C K F + S+L H IHT EKP+KC +
Sbjct: 387 FKRLSTLTKHKIIHA--------GEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEE 438
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF S+LT H + HT K FKC+ C K+F S +L H R+HTG +P+ C C K
Sbjct: 439 CGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKA 498
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
FR S H H ++P + G
Sbjct: 499 FRQSSTLTKHKIIHTG------------------------------EKPYKFEECG---- 524
Query: 635 IPKNQFFQSYFNNN--FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGR 692
F QS N ++ ++PYKC C +A+K+ L H H G+K +KC +CG+
Sbjct: 525 ---KAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGK 581
Query: 693 GFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKT 752
F + L H HTG KS+KC C AF +LRRH IH +PY C C K F
Sbjct: 582 AFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSH 641
Query: 753 SLNCKKHMKTHRYELAQQLQQHQQAAS 779
S KH + H E + ++ +A S
Sbjct: 642 SSALAKHKRIHTGEKPYKCKECGKAFS 668
Score = 204 bits (518), Expect = 8e-52
Identities = 113/328 (34%), Positives = 154/328 (46%), Gaps = 35/328 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F SS L +H R HT EKP+KCK CG+ F+ S L H++ HTG K +
Sbjct: 740 KPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYK 799
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ + +LT+H H KPYKC C + F+ + KH H
Sbjct: 800 CEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIH----------- 848
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
G+ + EE N S I T+E +P +S + + S
Sbjct: 849 ---AGEKLYKCEECGKAFNQSSNLTTHKIIHTKE--------KPSKSEECDKAFIWSSTL 897
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ + R+K + C C K+F +PS L H R+HTGEKPYKC+ECGK+F
Sbjct: 898 TEHKRIHTREKTYK----------CEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAF 947
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
+ STL H HTG+K + C C AF +L H +HTG KP+KC C F S
Sbjct: 948 SQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSS 1007
Query: 1265 RRKTHMQFHYKPDPKKAR---KPMTRSS 1289
H + H P K K RSS
Sbjct: 1008 TLTRHTRMHTGEKPYKCEECGKAFNRSS 1035
Score = 191 bits (486), Expect = 4e-48
Identities = 109/343 (31%), Positives = 158/343 (46%), Gaps = 24/343 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS L +H HTGEKPYKCK CG+ F S L H+ H G K +
Sbjct: 796 KPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYK 855
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ---------- 1074
C C +F + +LT H H KP K C++ F + +H + H
Sbjct: 856 CEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEEC 915
Query: 1075 ----TVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRP-- 1128
+ PS ++ G+ + EE + S I T E+ + +
Sbjct: 916 GKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAF 975
Query: 1129 QESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC--------CTYCPKSFKKPS 1180
++S+T++E ++ + + + E ++ +H C C K+F + S
Sbjct: 976 RKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSS 1035
Query: 1181 DLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKV 1240
L H IHTGEKPYKC+ECGK+F STL+ H + HT +K + C C AFS +L
Sbjct: 1036 KLTTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTR 1095
Query: 1241 HMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H RLHTG KP+KC C F+ S H H P K K
Sbjct: 1096 HKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKPYKCEK 1138
Score = 185 bits (470), Expect = 3e-46
Identities = 108/334 (32%), Positives = 148/334 (44%), Gaps = 32/334 (9%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K F SS L H HTGEK YKC+ CG+ F+ S L+ H++ HTG K +
Sbjct: 571 KKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPY 630
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-QTVPSAVSA 1082
C C +F+ + +L +H H KPYKC C + F + H H + P
Sbjct: 631 KCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKE 690
Query: 1083 TGET-------------EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQ 1129
+T G+ + EE N S T E +P
Sbjct: 691 CDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGE--------KPY 742
Query: 1130 ESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIH 1189
+ + S+ K + R+K + C C K+F S L RH RIH
Sbjct: 743 KCEECGKAFNWSSSLTKHKRIHTREKPFK----------CKECGKAFIWSSTLTRHKRIH 792
Query: 1190 TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
TGEKPYKC+ECGK+F+ STL H HTG+K + C C AF +L H +H G K
Sbjct: 793 TGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEK 852
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
+KC C F S TH H K P K+ +
Sbjct: 853 LYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEE 886
Score = 184 bits (468), Expect = 5e-46
Identities = 105/309 (33%), Positives = 140/309 (45%), Gaps = 32/309 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F SS L +H R HTGEKPYKC+ CG+ F S L H++ HTG K +
Sbjct: 292 KPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYK 351
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ + +L H TH KPYKC C++ F+ KH H
Sbjct: 352 CKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKIIH----------- 400
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
G+ + EE N S T E +P + + S+
Sbjct: 401 ---AGEKLYKCEECGKAFNRSSNLTIHKFIHTGE--------KPYKCEECGKAFNWSSSL 449
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
K + R+K + C C K+F S L RH RIHTGEKPYKC+ECGK+F
Sbjct: 450 TKHKRFHTREKPFK----------CKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAF 499
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
STL H HTG+K + C AF +L H +H+ KP+KC C F+
Sbjct: 500 RQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFS 559
Query: 1265 RRKTHMQFH 1273
TH H
Sbjct: 560 TLTTHKIIH 568
Score = 182 bits (463), Expect = 2e-45
Identities = 108/319 (33%), Positives = 147/319 (46%), Gaps = 32/319 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K FK+ S L H H G+K YKC+ CG+ F S L +H+ HTG K++
Sbjct: 544 KPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYK 603
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + +L RH H KPYKC C + F + KH + H TG
Sbjct: 604 CEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIH---------TG 654
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E C E + S+ + + IT TEE +P + + S
Sbjct: 655 EKPYK--CKECGKAFSNSSTLANHK---ITHTEE--------KPYKCKECDKTFKRLSTL 701
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
K +I +K + C C K+F + S+L H IHTGEKPYKC+ECGK+F
Sbjct: 702 TKHKIIHAGEKLYK----------CEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAF 751
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
S+L H + HT +K F C C AF +L H R+HTG KP+KC C F S
Sbjct: 752 NWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSS 811
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H H P K ++
Sbjct: 812 TLTKHKTIHTGEKPYKCKE 830
Score = 181 bits (460), Expect = 4e-45
Identities = 104/314 (33%), Positives = 136/314 (43%), Gaps = 60/314 (19%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C+ C K F SS L +H R HTGEKPYKC+ CG+ F S L H++ HTG K + C
Sbjct: 266 YKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCE 325
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ + +L +H H KPYKC C + F + H
Sbjct: 326 ECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHK---------------- 369
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
IT TEE +P + + S K
Sbjct: 370 --------------------------ITHTEE--------KPYKCKECDKAFKRLSTLTK 395
Query: 1147 DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTV 1206
+I +K + C C K+F + S+L H IHTGEKPYKC+ECGK+F
Sbjct: 396 HKIIHAGEKLYK----------CEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNW 445
Query: 1207 KSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRR 1266
S+L H + HT +K F C C AF +L H R+HTG KP+KC C FR S
Sbjct: 446 SSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFRQSSTL 505
Query: 1267 KTHMQFHYKPDPKK 1280
H H P K
Sbjct: 506 TKHKIIHTGEKPYK 519
Score = 180 bits (457), Expect = 1e-44
Identities = 103/325 (31%), Positives = 147/325 (45%), Gaps = 16/325 (4%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS L +H R HTGEKPYKCK CG+ F +S L +H+ THT K +
Sbjct: 320 KPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYK 379
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
C C+ +F +LT+H H K YKC C + F + + H H P
Sbjct: 380 CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEEC 439
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKI-----RPQESATVSEKV 1138
G+ + + + R K + F T K +P + +
Sbjct: 440 GKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAF 499
Query: 1139 LVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
S K +I +K + ++ C K+F++ L +H IH+ EKPYKC
Sbjct: 500 RQSSTLTKHKIIHTGEKPYKFEE----------CGKAFRQSLTLNKHKIIHSREKPYKCK 549
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+F STL H H G+KL+ C C AF+ SL H +HTG K +KC C
Sbjct: 550 ECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGK 609
Query: 1259 RFRTSGRRKTHMQFHYKPDPKKARK 1283
F S + H + H P K +
Sbjct: 610 AFLWSSTLRRHKRIHTGEKPYKCEE 634
Score = 179 bits (453), Expect = 3e-44
Identities = 108/322 (33%), Positives = 147/322 (45%), Gaps = 39/322 (12%)
Query: 932 NVTTRLI-----QESSQEELDLQAQGSQFLEDNE--DQSRRSYRCDYCNKGFKKSSHLKQ 984
N+TT I + S EE D S L +++ ++Y+C+ C K F + SHL
Sbjct: 868 NLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTT 927
Query: 985 HVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMAT 1044
H R HTGEKPYKC+ CG+ F S L +H+ HTG K + C C +F + +LT H
Sbjct: 928 HKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKII 987
Query: 1045 HMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNA 1104
H KPYKC C + F + +H + H TGE + EE N
Sbjct: 988 HTGEKPYKCEECGKAFSQSSTLTRHTRMH---------TGEKP-----YKCEECGKAFNR 1033
Query: 1105 SRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPK 1164
S K I T E +P + + + S + R+K +
Sbjct: 1034 SSKLTTHKIIHTGE--------KPYKCEECGKAFISSSTLNGHKRIHTREKPYK------ 1079
Query: 1165 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFS 1224
C C K+F + S L RH R+HTGEKPYKC ECGK+F S L H HTG+K +
Sbjct: 1080 ----CEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKPYK 1135
Query: 1225 CHVCSNAFSTKGSLKVHMRLHT 1246
C C AF+ L H ++HT
Sbjct: 1136 CEKCGKAFNQSSILTNHKKIHT 1157
Score = 167 bits (424), Expect = 7e-41
Identities = 102/321 (31%), Positives = 139/321 (43%), Gaps = 32/321 (9%)
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ +S +C C K F SS L H HT +KPYKC+ CG+ F L +H+ K
Sbjct: 206 TEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKI 265
Query: 1023 FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSA 1082
+ C C +F + +LTRH H KPYKC C + F + KH + H
Sbjct: 266 YKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIH--------- 316
Query: 1083 TGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQS 1142
TGE + E + SR S T + + + +P + + S
Sbjct: 317 TGEKP-------YKCEECGKAFSRSS-----TLAKHKRIHTGE-KPYKCKECGKAFSNSS 363
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
+I+ +K + C C K+FK+ S L +H IH GEK YKC+ECGK
Sbjct: 364 TLANHKITHTEEKPYK----------CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGK 413
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+F S L H HTG+K + C C AF+ SL H R HT KPFKC C F
Sbjct: 414 AFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIW 473
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
S H + H P K +
Sbjct: 474 SSTLTRHKRIHTGEKPYKCEE 494
Score = 152 bits (384), Expect = 3e-36
Identities = 100/301 (33%), Positives = 135/301 (44%), Gaps = 31/301 (10%)
Query: 4 CGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERND 63
C ++ C +H + G LN T +V +C L F K RH H
Sbjct: 126 CKSVDECKVHKE--GYNKLNQCLTTAQSKV---FQCGKYLKVFYKFLNSNRHTIRHT-GK 179
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDPT-CPVCNKKFSRVASLKAHIMLHEKEENLI 122
K +C +C ++F + + T HKC + E C C K F ++L H +H +++
Sbjct: 180 KCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYK 239
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182
C ECG F S L H + A + + C+ C K F SS L H + H +
Sbjct: 240 CEECGKAFKQLSTLTTH----KIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEK--- 292
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
Y C CGK F S L +H RIHTGE+P+KC ECGKAF++ L
Sbjct: 293 -------------PYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLAK 339
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
H HTGEKP+ C C AFS L +H + H+E K Y C EC FK L +L
Sbjct: 340 HKRIHTGEKPYKCKECGKAFSNSSTLANH-KITHTEEK---PYKCKECDKAFKRLSTLTK 395
Query: 303 H 303
H
Sbjct: 396 H 396
Score = 145 bits (367), Expect = 3e-34
Identities = 101/335 (30%), Positives = 137/335 (40%), Gaps = 38/335 (11%)
Query: 954 QFLEDNEDQSRRS----YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGV 1009
+FL N R + ++C C K F H QH + EK KCK C + F S
Sbjct: 165 KFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSST 224
Query: 1010 LKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKH 1069
L +H++ HT K + C C +F +LT H K YKC C + F + +H
Sbjct: 225 LTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRH 284
Query: 1070 MKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQ 1129
+ H TGE + HS A K +I
Sbjct: 285 KRIH---------TGEKPYKCEECGKAFSHSSTLAKHK-----------------RIHTG 318
Query: 1130 ESATVSEKVLVQSAAEKDRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRI 1188
E E + R S L + K+ ++P C C K+F S L H
Sbjct: 319 EKPYKCE----ECGKAFSRSSTLAKHKRIHTGEKPYK---CKECGKAFSNSSTLANHKIT 371
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HT EKPYKC EC K+F STL H H G+KL+ C C AF+ +L +H +HTG
Sbjct: 372 HTEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGE 431
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
KP+KC C F S H +FH + P K ++
Sbjct: 432 KPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKE 466
Score = 122 bits (307), Expect = 2e-27
Identities = 62/148 (41%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS ++ L H K +H E+ + C C KAF++++ L EH H
Sbjct: 936 KPYKCEECGKAFSQSSTLTTH-KIIHTGEKPYKCEECGKAFRKSSTLTEHKIIH------ 988
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF++ S L RH+R+HTGE+P+ C C KAFN+ S L H HTG
Sbjct: 989 TGEKP--YKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTG 1046
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H KR H+
Sbjct: 1047 EKPYKCEECGKAFISSSTLNGH-KRIHT 1073
Score = 119 bits (298), Expect = 3e-26
Identities = 58/145 (40%), Positives = 84/145 (57%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC++ F ++ L +H KE+H ++ + C C KAFK+ + L H +
Sbjct: 211 KCKECEKTFHWSSTLTNH-KEIHTEDKPYKCEECGKAFKQLSTLTTH--------KIICA 261
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
K +++KC+ C KAF S L RH RIHTGE+P+ C C KAF+ S L H + HTGE+P
Sbjct: 262 KEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKP 321
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C F++ S + H KR H+
Sbjct: 322 YKCEECGKAFSRSSTLAKH-KRIHT 345
Score = 116 bits (291), Expect = 2e-25
Identities = 59/156 (37%), Positives = 86/156 (55%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S L + E + ++C EC +AF + L H K + +E+I+ C C KAF ++
Sbjct: 222 SSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTH-KIICAKEKIYKCEECGKAFLWSST 280
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C KAF+ S L +H RIHTGE+P+ C C KAF+
Sbjct: 281 LTRHKRIH------TGEKP--YKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFS 332
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ S L H + HTGE+PYKC C F+ S + H
Sbjct: 333 RSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANH 368
Score = 116 bits (291), Expect = 2e-25
Identities = 58/162 (35%), Positives = 87/162 (53%), Gaps = 21/162 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH-QAGPS 1713
+ ++C EC +AF ++ L H K +H E+++ C C KAF ++++L H H + PS
Sbjct: 824 KPYKCKECGKAFKHSSALAKH-KIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPS 882
Query: 1714 LSSQ-------------------KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
S + + + +KC+ C KAF++PS L H R+HTGE+P+ C
Sbjct: 883 KSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEE 942
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
C KAF+Q S L H HTGE+PYKC C F + S + H
Sbjct: 943 CGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEH 984
Score = 115 bits (289), Expect = 3e-25
Identities = 64/169 (37%), Positives = 91/169 (53%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S L + + ++C EC +AF+ ++ L H K +H E+ + C
Sbjct: 996 CEECG-KAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTH-KIIHTGEKPYKCE 1053
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF ++ L H + H + +KP +KC+ C KAF++ S L RH R+HTGE+P
Sbjct: 1054 ECGKAFISSSTLNGHKRIH------TREKP--YKCEECGKAFSQSSTLTRHKRLHTGEKP 1105
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C C KAF + SAL H HTGE+PYKC C F Q S + H K
Sbjct: 1106 YKCGECGKAFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKK 1154
Score = 115 bits (287), Expect = 5e-25
Identities = 56/142 (39%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L H K +H ++++ C C KAF ++ L H H S
Sbjct: 544 KPYKCKECGKAFKQFSTLTTH-KIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKS- 601
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KC+ C KAF S L RH RIHTGE+P+ C C KAF+ SAL H + HTG
Sbjct: 602 -------YKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTG 654
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ S + H
Sbjct: 655 EKPYKCKECGKAFSNSSTLANH 676
Score = 113 bits (283), Expect = 1e-24
Identities = 64/176 (36%), Positives = 84/176 (47%), Gaps = 21/176 (11%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S LA E + ++C ECD+ F + L H K +H E+++ C C KAF R+++
Sbjct: 670 SSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKH-KIIHAGEKLYKCEECGKAFNRSSN 728
Query: 1701 LKEHMQTHQA---------------GPSLSSQK-----PRVFKCDTCEKAFAKPSQLERH 1740
L H H SL+ K + FKC C KAF S L RH
Sbjct: 729 LTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRH 788
Query: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
RIHTGE+P+ C C KAF++ S L H HTGE+PYKC C F S + H
Sbjct: 789 KRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKH 844
Score = 112 bits (281), Expect = 3e-24
Identities = 66/173 (38%), Positives = 91/173 (52%), Gaps = 11/173 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S LA + + ++C EC +AFS+++ L +H K H E+ + C
Sbjct: 632 CEECG-KAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANH-KITHTEEKPYKCK 689
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C K FKR + L +H H AG L +KC+ C KAF + S L H IHTGE+P
Sbjct: 690 ECDKTFKRLSTLTKHKIIH-AGEKL-------YKCEECGKAFNRSSNLTIHKFIHTGEKP 741
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+ C C KAFN S+L H + HT E+P+KC C F S + H KR H+
Sbjct: 742 YKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRH-KRIHT 793
Score = 112 bits (280), Expect = 3e-24
Identities = 68/182 (37%), Positives = 86/182 (47%), Gaps = 22/182 (12%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S LA E + ++C ECD+AF + L H K +H E+++ C C KAF R+++
Sbjct: 362 SSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKH-KIIHAGEKLYKCEECGKAFNRSSN 420
Query: 1701 LKEHMQTHQA---------------GPSLSSQK-----PRVFKCDTCEKAFAKPSQLERH 1740
L H H SL+ K + FKC C KAF S L RH
Sbjct: 421 LTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRH 480
Query: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRA 1800
RIHTGE+P+ C C KAF Q S L H HTGE+PYK C F Q + H K
Sbjct: 481 KRIHTGEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKH-KII 539
Query: 1801 HS 1802
HS
Sbjct: 540 HS 541
Score = 112 bits (279), Expect = 4e-24
Identities = 55/142 (38%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF ++ L H K +H E+ + C C KAF ++ L +H + H
Sbjct: 264 KIYKCEECGKAFLWSSTLTRH-KRIHTGEKPYKCEECGKAFSHSSTLAKHKRIH------ 316
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF++ S L +H RIHTGE+P+ C C KAF+ S L H HT
Sbjct: 317 TGEKP--YKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTE 374
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F + S + H
Sbjct: 375 EKPYKCKECDKAFKRLSTLTKH 396
Score = 112 bits (279), Expect = 4e-24
Identities = 57/142 (40%), Positives = 80/142 (56%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K +H RE+ C C KAF ++ L H + H
Sbjct: 740 KPYKCEECGKAFNWSSSLTKH-KRIHTREKPFKCKECGKAFIWSSTLTRHKRIH------ 792
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF++ S L +H IHTGE+P+ C C KAF SAL H H G
Sbjct: 793 TGEKP--YKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAG 850
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+ YKC C F Q SN+ H
Sbjct: 851 EKLYKCEECGKAFNQSSNLTTH 872
Score = 108 bits (270), Expect = 5e-23
Identities = 54/142 (38%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS ++ L H K +H E+ + C C KAF R++ L +H + H
Sbjct: 292 KPYKCEECGKAFSHSSTLAKH-KRIHTGEKPYKCEECGKAFSRSSTLAKHKRIH------ 344
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF+ S L H HT E+P+ C C+KAF + S L H H G
Sbjct: 345 TGEKP--YKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKIIHAG 402
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+ YKC C F + SN+ +H
Sbjct: 403 EKLYKCEECGKAFNRSSNLTIH 424
Score = 108 bits (270), Expect = 5e-23
Identities = 55/142 (38%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K +H E+ + C C KAF ++ L+ H + H
Sbjct: 572 KLYKCEECGKAFNHSSSLSTH-KIIHTGEKSYKCEECGKAFLWSSTLRRHKRIH------ 624
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF+ S L +H RIHTGE+P+ C C KAF+ S L H HT
Sbjct: 625 TGEKP--YKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTE 682
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F + S + H
Sbjct: 683 EKPYKCKECDKTFKRLSTLTKH 704
Score = 107 bits (266), Expect = 1e-22
Identities = 51/133 (38%), Positives = 68/133 (51%), Gaps = 1/133 (0%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F SS L H R HT EKPYKC+ CG+ F S L H++ HTG K +
Sbjct: 1048 KPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYK 1107
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + +LT+H H KPYKC C + F + H K H T+ +
Sbjct: 1108 CGECGKAFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIH-TITPVIPLLW 1166
Query: 1085 ETEGGDICMEEEE 1097
E E G +E E
Sbjct: 1167 EAEAGGSRGQEME 1179
Score = 105 bits (261), Expect = 5e-22
Identities = 59/142 (41%), Positives = 76/142 (53%), Gaps = 10/142 (7%)
Query: 1661 ECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPR 1720
EC +AF + L H K +H RE+ + C C KAFK+ + L H H AG L
Sbjct: 522 ECGKAFRQSLTLNKH-KIIHSREKPYKCKECGKAFKQFSTLTTHKIIH-AGKKL------ 573
Query: 1721 VFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKC 1780
+KC+ C KAF S L H IHTGE+ + C C KAF S L+ H + HTGE+PYKC
Sbjct: 574 -YKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKC 632
Query: 1781 AYCVMGFTQKSNMKLHMKRAHS 1802
C F+ S + H KR H+
Sbjct: 633 EECGKAFSHSSALAKH-KRIHT 653
Score = 103 bits (256), Expect = 2e-21
Identities = 58/148 (39%), Positives = 81/148 (54%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS ++ L H K +H E+ + C C KAFK ++ L +H H AG L
Sbjct: 796 KPYKCEECGKAFSRSSTLTKH-KTIHTGEKPYKCKECGKAFKHSSALAKHKIIH-AGEKL 853
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KC+ C KAF + S L H IHT E+P C+KAF S L H + HT
Sbjct: 854 -------YKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTR 906
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+ YKC C F+Q S++ H KR H+
Sbjct: 907 EKTYKCEECGKAFSQPSHLTTH-KRMHT 933
Score = 100 bits (248), Expect = 2e-20
Identities = 54/142 (38%), Positives = 76/142 (53%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K H RE+ C C KAF ++ L H + H
Sbjct: 432 KPYKCEECGKAFNWSSSLTKH-KRFHTREKPFKCKECGKAFIWSSTLTRHKRIH------ 484
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF + S L +H IHTGE+P+ C KAF Q L H H+
Sbjct: 485 TGEKP--YKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSR 542
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F Q S + H
Sbjct: 543 EKPYKCKECGKAFKQFSTLTTH 564
Score = 99.8 bits (247), Expect = 2e-20
Identities = 50/125 (40%), Positives = 63/125 (50%), Gaps = 3/125 (2%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F S L H IHT +KPYKC+ECGK+F STL H +K++ C C
Sbjct: 212 CKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEEC 271
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKAR---KPM 1285
AF +L H R+HTG KP+KC C F S H + H P K K
Sbjct: 272 GKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAF 331
Query: 1286 TRSSS 1290
+RSS+
Sbjct: 332 SRSST 336
Score = 97.8 bits (242), Expect = 8e-20
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 9/119 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF S++ L H K +H RE+ + C C KAF +++ L H + H
Sbjct: 1048 KPYKCEECGKAFISSSTLNGH-KRIHTREKPYKCEECGKAFSQSSTLTRHKRLH------ 1100
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
+ +KP +KC C KAF + S L +H IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 1101 TGEKP--YKCGECGKAFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIHT 1157
Score = 95.1 bits (235), Expect = 6e-19
Identities = 54/167 (32%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S +L + + +C EC +AF ++ L H K +H E+ + C
Sbjct: 436 CEECG-KAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRH-KRIHTGEKPYKCE 493
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF++++ L +H H + +KP +K + C KAF + L +H IH+ E+P
Sbjct: 494 ECGKAFRQSSTLTKHKIIH------TGEKP--YKFEECGKAFRQSLTLNKHKIIHSREKP 545
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ C C KAF Q S L H H G++ YKC C F S++ H
Sbjct: 546 YKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTH 592
Score = 62.8 bits (151), Expect = 3e-09
Identities = 32/96 (33%), Positives = 44/96 (45%)
Query: 1174 KSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFS 1233
K F K + RH HTG+K +KC +C KSF ++ H + +K C C F
Sbjct: 161 KVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFH 220
Query: 1234 TKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTH 1269
+L H +HT KP+KC C F+ TH
Sbjct: 221 WSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTH 256
Score = 59.7 bits (143), Expect = 3e-08
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 8/115 (6%)
Query: 1682 RERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHS 1741
+ ++ C K F + + H H + FKC C K+F +H
Sbjct: 150 QSKVFQCGKYLKVFYKFLNSNRHTIRHTG--------KKCFKCKKCVKSFCIRLHKTQHK 201
Query: 1742 RIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
++ E+ C CEK F+ S L H + HT ++PYKC C F Q S + H
Sbjct: 202 CVYITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTH 256
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/91 (27%), Positives = 37/91 (40%)
Query: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK 1252
K ++C + K F + H HTG+K F C C +F + H ++ K K
Sbjct: 152 KVFQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCK 211
Query: 1253 CPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C CE F S H + H + P K +
Sbjct: 212 CKECEKTFHWSSTLTNHKEIHTEDKPYKCEE 242
>gi|62243640 zinc finger protein 107 [Homo sapiens]
Length = 783
Score = 295 bits (754), Expect = 4e-79
Identities = 203/710 (28%), Positives = 305/710 (42%), Gaps = 73/710 (10%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLI 122
K +C++ + F+ N +K H+G C C+K F ++ L H +H + +
Sbjct: 74 KIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYK 133
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182
C ECG F S L H H G + + C+ C K F SS+L H H + + +
Sbjct: 134 CEECGKAFNWFSTLTKHKRIH----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNK 189
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
C CGK F++ S LT H IHTGE+P+K ECGK F+Q L T
Sbjct: 190 ----------------CEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTT 233
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
I HTGE + C C AF+ NL +H +R+H+ K Y C EC F +LN
Sbjct: 234 QKILHTGENLYKCKECGKAFNLFSNLTNH-KRIHAGEK---PYKCKECGRAFNISSNLNK 289
Query: 303 HISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQL 361
K+H GG N + A L+ T + +P + V Q
Sbjct: 290 Q-EKIHTGGKLNKCEECDKAF--------NRSLKLTAHKKILMEEKPYKCEECGKVFNQF 340
Query: 362 LELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAK--T 419
L+ + +G+ P ++ + ++ + H K T
Sbjct: 341 STLTRHKIIHTGEKPYKCKECGKAFNQSSNLTE---------------------HKKIHT 379
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
+ + + N+ ++ + + E P K ++ K +S L + G
Sbjct: 380 AEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAF--NRSSTLTRHKKIHTGE 437
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
+ + C C + F + S+L H +IHT EKP+KC +C +AF STLT H + HTG K +K
Sbjct: 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK 497
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRH 599
C+ C K+F+ S L H +HT + C K F+ S HR H H + H
Sbjct: 498 CEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEH 557
Query: 600 QRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQ---FFQSYFNNNFVNEADRP 656
KV +N+ + I+ T L + + F + N+ + ++P
Sbjct: 558 ----GKVFNQSSNLTT------QKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKP 607
Query: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716
+KC C +AY + +L H R HTGEKP++C++CG+ F + L H HTG K +KC
Sbjct: 608 HKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCK 667
Query: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
C AF +L H IH +PY C C K F S N H K H E
Sbjct: 668 ECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSE 717
Score = 283 bits (724), Expect = 1e-75
Identities = 203/680 (29%), Positives = 304/680 (44%), Gaps = 90/680 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + SQ RH H +KP++C++C + F +LT+HK H+GE P
Sbjct: 160 YKCEECGKAFNQSSQLTRHKIIH-TEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKY 218
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS+ + L +LH E C ECG F L S L H H AG + + C
Sbjct: 219 EECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIH----AGEKPYKC 274
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSS----TRSYNRNIDRSGF--------TYSCPHCG 203
K C + F SS L + K H +++ +++NR++ + Y C CG
Sbjct: 275 KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECG 334
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F + S LTRH IHTGE+P+KC ECGKAFNQ L H HT EK + C C AF+
Sbjct: 335 KVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFN 394
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAH 323
Q NL +H ++++S K Y C EC F +L H K+H G + A
Sbjct: 395 QHSNLINH-RKIYSGEK---PYKCEECGKAFNRSSTLTRH-KKIHTGEKPYKCEECDRAF 449
Query: 324 VLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQL 382
++ L TE + +P + + L++ + +G+ P ++
Sbjct: 450 SQSSNL--------TEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEEC 501
Query: 383 SITVGINQDILQQAL----------ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSV 432
+ + + + E G + ++H T + + V
Sbjct: 502 GKAFNQSYQLTRHKIVHTKEKLNKCEEFG-KAFKQSSHRTIHKIIHTGEKPYKCEEHGKV 560
Query: 433 SNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREE----NGVRWHVCPYCA 488
N+ ++ T +K + E L K E+ K+ L +I G + H C C
Sbjct: 561 FNQSSNLT---TQKIIHTGENLYKFEE---HGKAFNLFSNITNHKIIYTGEKPHKCEECG 614
Query: 489 KEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 548
K + + S+L H RIHT EKP++C +C +AF STL H HTG K +KC+ C K+F+
Sbjct: 615 KAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFN 674
Query: 549 TSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-R 607
S +L H ++HTG +P+ C C K F S + TH +K+ KP K
Sbjct: 675 LSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH----------KKIHTSEKPYKCEE 724
Query: 608 VGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYK 667
GK+ NQ F S + ++ ++PYKC RA+
Sbjct: 725 CGKS-------------------------FNQ-FSSLNIHKIIHTGEKPYKCGDYGRAFN 758
Query: 668 KSCHLKQHIRSHTGEKPFKC 687
S +L H + HTGEKP+KC
Sbjct: 759 LSSNLTTHKKIHTGEKPYKC 778
Score = 270 bits (689), Expect = 1e-71
Identities = 202/720 (28%), Positives = 293/720 (40%), Gaps = 109/720 (15%)
Query: 98 CNKK---FSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHA 154
CNK F + ++ + H ++ C EC F + SQL H H + +
Sbjct: 78 CNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR----VNSYK 133
Query: 155 CKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTR 214
C+ C K F S L +H + H + Y C CGK F + SQLTR
Sbjct: 134 CEECGKAFNWFSTLTKHKRIHTGEK----------------PYKCEECGKAFNQSSQLTR 177
Query: 215 HIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQR 274
H IHT E+P KC ECGKAF Q L H I HTGEKP+ C FSQ +L + Q+
Sbjct: 178 HKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTT--QK 235
Query: 275 VHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLP 334
+ +N Y C EC F +L H ++H G A +++ L
Sbjct: 236 ILHTGEN--LYKCKECGKAFNLFSNLTNH-KRIHAGEKPYKCKECGRAFNISSNL----- 287
Query: 335 LQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
+ + + + + L+L+ + + P ++ + +
Sbjct: 288 --NKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTR 345
Query: 395 QALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
+ H + + A N SS E AE+ + E K
Sbjct: 346 HKI-----------IHTGEKPYKCKECGKAFNQ--SSNLTEHKKIHTAEKSYKCEECGKA 392
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ +I + + +G + + C C K F + S L RH +IHT EKP+KC +
Sbjct: 393 FNQHSNLINHRKIY--------SGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEE 444
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C RAF+ S LT H K HTG K +KC+ C K+F+ +L H R+HTG +P+ C C K
Sbjct: 445 CDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKA 504
Query: 575 FRTSGHRKTHIASHFK-----------------HTELRKMRHQ-RKPAKVRV-GKTNIPV 615
F S H H K H + K+ H KP K GK
Sbjct: 505 FNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQS 564
Query: 616 PDIPLQEPILITDLGLIQPIPKNQFFQSYFN-----------------------NNFVN- 651
++ Q+ I+ T L + + F + N N F N
Sbjct: 565 SNLTTQK-IIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNL 623
Query: 652 -------EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHI 704
++PY+C C +A+ S L +H HTGEKP+KC +CG+ F + L AH
Sbjct: 624 TIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHK 683
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFK--TSLNCKKHMKT 762
+ HTG K +KC C AF +L H IH +PY C C K+F +SLN K + T
Sbjct: 684 KIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHT 743
Score = 258 bits (658), Expect = 5e-68
Identities = 182/605 (30%), Positives = 262/605 (43%), Gaps = 91/605 (15%)
Query: 35 NFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPT 94
N +KC+ C +F S H R H +KP++C +C + FN+ NL + H+G
Sbjct: 242 NLYKCKECGKAFNLFSNLTNHKRIHA-GEKPYKCKECGRAFNISSNLNKQEKIHTGGKLN 300
Query: 95 -CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQH 153
C C+K F+R L AH + +E+ C ECG F S L H H G + +
Sbjct: 301 KCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIH----TGEKPY 356
Query: 154 ACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLT 213
CK C K F SS L EH K H + +Y C CGK F + S L
Sbjct: 357 KCKECGKAFNQSSNLTEHKKIHTAEK----------------SYKCEECGKAFNQHSNLI 400
Query: 214 RHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQ 273
H +I++GE+P+KC ECGKAFN+ L H HTGEKP+ C C AFSQ NL H +
Sbjct: 401 NHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEH-K 459
Query: 274 RVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG---------GPQNSTSSTETAHV 324
++H+ K Y C EC F +L H ++H G G + S T H
Sbjct: 460 KIHTGEK---PYKCEECGKAFNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLTRHK 515
Query: 325 LTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSI 384
+ T + L + E + A Q S + + +I +G+ P ++
Sbjct: 516 IVHTKEK---LNKCE-EFGKAFKQSSHRTIHKII------------HTGEKPYKCEEHGK 559
Query: 385 TVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQ 444
+ ++ Q + ++G + H A N S+++N + T +
Sbjct: 560 VFNQSSNLTTQKIIHTGENLYKFEEHGK-----------AFNL-FSNITNHKIIYTGEKP 607
Query: 445 EKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIH 504
K +E + ++ I K R G + + C C K F S L RH IH
Sbjct: 608 HKCEECGKAYNRFSNLTIHK---------RIHTGEKPYQCAECGKAFNCSSTLNRHKIIH 658
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVR 564
T EKP+KC +C +AF + STLTAH K HTG K +KC+ C K+F+ S +L H ++HT +
Sbjct: 659 TGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEK 718
Query: 565 PFACPHCDKKFRTSGHRKTHIASHFKH------------------TELRKMRHQRKPAKV 606
P+ C C K F H H T +K+ KP K
Sbjct: 719 PYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYKC 778
Query: 607 RVGKT 611
GKT
Sbjct: 779 EYGKT 783
Score = 238 bits (607), Expect = 4e-62
Identities = 189/776 (24%), Positives = 300/776 (38%), Gaps = 93/776 (11%)
Query: 531 THTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF----RTSGHRKTHI- 585
T T K F+C +K F + + R HTG + F C C K F + + HR+ H
Sbjct: 69 TATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR 128
Query: 586 ASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
+ +K E K + +F +
Sbjct: 129 VNSYKCEECGKAFN----------------------------------------WFSTLT 148
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
+ ++ ++PYKC C +A+ +S L +H HT EKP KC +CG+ F A L H
Sbjct: 149 KHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKI 208
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY 765
HTG K +K C F+ L +H Y C C K F N H + H
Sbjct: 209 IHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAG 268
Query: 766 ELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQ 825
E + ++ +A +I + Q+ + ++ E D+ + + A+ + +++ +P
Sbjct: 269 EKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPY 328
Query: 826 HVVGTEEAG--LGQ----------QLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQ 873
EE G Q ++P + E G Q ++ + ++ A++
Sbjct: 329 K---CEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQS---SNLTEHKKIHTAEK 382
Query: 874 SFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNV 933
S++ + F + + + +F++ S L
Sbjct: 383 SYKCEECGKAFNQHSNLINHRKI-----YSGEKPYKCEECGKAFNRSSTLTRHKKIHTGE 437
Query: 934 TTRLIQESSQEELDLQAQGSQFLEDNE-DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGE 992
+E + +Q S E + + Y+C+ C K F + S L +H R HTGE
Sbjct: 438 KPYKCEECDR----AFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGE 493
Query: 993 KPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYK 1052
KPYKC+ CG+ F S L H+ HT K C +F + T H H KPYK
Sbjct: 494 KPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYK 553
Query: 1053 CP-----FCEEGFRTT---VHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNA 1104
C F + TT +H +++ + + A + I E+ H
Sbjct: 554 CEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEEC 613
Query: 1105 SRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPK 1164
K+ T + + +P + A + S + +I +K +
Sbjct: 614 G-KAYNRFSNLTIHKRIHTGE-KPYQCAECGKAFNCSSTLNRHKIIHTGEKPYK------ 665
Query: 1165 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFS 1224
C C K+F S L H +IHTGEKPYKC+ECGK+F S L H K HT +K +
Sbjct: 666 ----CKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYK 721
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK 1280
C C +F+ SL +H +HTG KP+KC F S TH + H P K
Sbjct: 722 CEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYK 777
Score = 218 bits (554), Expect = 6e-56
Identities = 166/651 (25%), Positives = 265/651 (40%), Gaps = 92/651 (14%)
Query: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACA 256
+ C C K+F SQLT+H RIHT +KC ECGKAFN L H HTGEKP+ C
Sbjct: 104 FKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCE 163
Query: 257 FCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNST 316
C AF+Q L H + +H+E K C EC FK L H +H G
Sbjct: 164 ECGKAFNQSSQLTRH-KIIHTEEKPN---KCEECGKAFKQASHLTIH-KIIHTGEKPYKY 218
Query: 317 SS-----TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVE 371
++++H+ T + T + + L+ +
Sbjct: 219 EECGKVFSQSSHLTTQKILHT------------GENLYKCKECGKAFNLFSNLTNHKRIH 266
Query: 372 SGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSS 431
+G+ P ++ I+ ++ +Q ++G + + C
Sbjct: 267 AGEKPYKCKECGRAFNISSNLNKQEKIHTG-----GKLNKCEEC--------------DK 307
Query: 432 VSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEF 491
N T ++ +E P K ++ K + + L G + + C C K F
Sbjct: 308 AFNRSLKLTAHKKILMEEKPYKCEECGK--VFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365
Query: 492 RKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSG 551
+ S+L H +IHT EK +KC +C +AF S L H K ++G K +KC+ C K+F+ S
Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425
Query: 552 SLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH-FKHTELRKMRHQ----RK 602
+L H ++HTG +P+ C CD+ F S H+K H +K E K ++ K
Sbjct: 426 TLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTK 485
Query: 603 PAKVRVGKTNIPVPDI--PLQEPILITDLGLI---QPIPKNQFFQSYFN-------NNFV 650
++ G+ + + +T ++ + + K + F F + +
Sbjct: 486 HKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKII 545
Query: 651 NEADRPYKC------------------------FYCHRAYKKSCHLKQHIRSH----TGE 682
+ ++PYKC Y + K+ +L +I +H TGE
Sbjct: 546 HTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGE 605
Query: 683 KPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYM 742
KP KC +CG+ + L H R HTG K ++C C AF +L RH IH +PY
Sbjct: 606 KPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYK 665
Query: 743 CPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQAS 793
C C K F S H K H E + ++ +A + + + + S
Sbjct: 666 CKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTS 716
Score = 199 bits (507), Expect = 2e-50
Identities = 109/330 (33%), Positives = 161/330 (48%), Gaps = 26/330 (7%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS L +H + HTGEKPYKC+ C R F S L H+K HTG K +
Sbjct: 410 KPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYK 469
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F +LT+H H KPYKC C + F + +H H
Sbjct: 470 CEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTK--------- 520
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVL--- 1139
E + C EE + + +S ++ ++I E+ + + K+ Q S ++K++
Sbjct: 521 --EKLNKC--EEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTG 576
Query: 1140 ------VQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEK 1193
+ + S + + + E H C C K++ + S+L H RIHTGEK
Sbjct: 577 ENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHK--CEECGKAYNRFSNLTIHKRIHTGEK 634
Query: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKC 1253
PY+C ECGK+F STL+ H HTG+K + C C AF+ +L H ++HTG KP+KC
Sbjct: 635 PYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKC 694
Query: 1254 PHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C F S TH + H P K +
Sbjct: 695 EECGKAFNQSSNLTTHKKIHTSEKPYKCEE 724
Score = 184 bits (466), Expect = 9e-46
Identities = 160/630 (25%), Positives = 239/630 (37%), Gaps = 105/630 (16%)
Query: 658 KCFYCHRAYKKSCHLKQHIRSHTG-------------EKPFKCSQCGRGFVSAGVLKAHI 704
KC Y + +K C H G K F+C++ + F +
Sbjct: 36 KCEYENLQLRKGCKHVDECTGHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYK 95
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR 764
R HTG K FKC C+ +F L +H IH + Y C C K F KH + H
Sbjct: 96 RRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT 155
Query: 765 YELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEP 824
E + ++ +A + QS Q T+ ++ I ++E P E + L
Sbjct: 156 GEKPYKCEECGKAFN--------QSSQL-TRHKI-IHTEEKPNKCEECGKAFKQASHLTI 205
Query: 825 QHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGF 884
++ T E +P + +E G V Q H+ + + ++ + F
Sbjct: 206 HKIIHTGE---------KPYKYEECGKVFSQS---SHLTTQKILHTGENLYKCKECGKAF 253
Query: 885 TVTDTYHQQPQFPPVQQLQDSSTL-ESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQ 943
+ + ++ + +S++ ++Q + + G ++
Sbjct: 254 NLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIH---TGGKLNKCEECDKAFN 310
Query: 944 EELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRG 1003
L L A +E+ + Y+C+ C K F + S L +H HTGEKPYKCK CG+
Sbjct: 311 RSLKLTAHKKILMEE------KPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKA 364
Query: 1004 FVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTT 1063
F S L H+K HT K++ C C +F + +L H + KPYKC C + F +
Sbjct: 365 FNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRS 424
Query: 1064 VHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQL 1123
+H K H TGE + E DR S+ S TE +
Sbjct: 425 STLTRHKKIH---------TGE-------KPYKCEECDRAFSQSS-----NLTEHK---- 459
Query: 1124 AKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLV 1183
KI E E+ C K+F + S L
Sbjct: 460 -KIHTGEKPYKCEE----------------------------------CGKAFNRFSTLT 484
Query: 1184 RHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMR 1243
+H RIHTGEKPYKC+ECGK+F L H HT +KL C AF +H
Sbjct: 485 KHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKI 544
Query: 1244 LHTGAKPFKCPHCELRFRTSGRRKTHMQFH 1273
+HTG KP+KC F S T H
Sbjct: 545 IHTGEKPYKCEEHGKVFNQSSNLTTQKIIH 574
Score = 184 bits (466), Expect = 9e-46
Identities = 103/325 (31%), Positives = 154/325 (47%), Gaps = 22/325 (6%)
Query: 968 RCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSV 1027
+C+ C K FK++SHL H HTGEKPYK + CG+ F S L + + HTG + C
Sbjct: 189 KCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKE 248
Query: 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETE 1087
C +F +LT H H KPYKC C F + + K K H
Sbjct: 249 CGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIH-------------T 295
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVL--VQSA 1143
GG + EE + + + + + + I E+ + + K+ Q S K++ +
Sbjct: 296 GGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKP 355
Query: 1144 AEKDRISELRDKQAELQDEPK-----HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
+ + ++ + L + K + C C K+F + S+L+ H +I++GEKPYKC+
Sbjct: 356 YKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCE 415
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+F STL H K HTG+K + C C AFS +L H ++HTG KP+KC C
Sbjct: 416 ECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGK 475
Query: 1259 RFRTSGRRKTHMQFHYKPDPKKARK 1283
F H + H P K +
Sbjct: 476 AFNRFSTLTKHKRIHTGEKPYKCEE 500
Score = 173 bits (438), Expect = 2e-42
Identities = 114/346 (32%), Positives = 150/346 (43%), Gaps = 70/346 (20%)
Query: 23 NAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLT 82
N N Y +KCE C +F + S RH + H +KP++C++C + F+ NLT
Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIH-TGEKPYKCEECDRAFSQSSNLT 456
Query: 83 LHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHME 141
HK H+GE P C C K F+R ++L H +H E+ C ECG F QL H
Sbjct: 457 EHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKI 516
Query: 142 EHRQEL------------------------AGTRQHACKACKKEFETSSEL--------- 168
H +E G + + C+ K F SS L
Sbjct: 517 VHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTG 576
Query: 169 ------KEHMK--------THYKIRVSST---------RSYNR--------NIDRSGFTY 197
+EH K T++KI + ++YNR I Y
Sbjct: 577 ENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPY 636
Query: 198 SCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAF 257
C CGK F S L RH IHTGE+P+KC ECGKAFN L H HTGEKP+ C
Sbjct: 637 QCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEE 696
Query: 258 CPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
C AF+Q NL +H +++H+ K Y C EC F SLN H
Sbjct: 697 CGKAFNQSSNLTTH-KKIHTSEK---PYKCEECGKSFNQFSSLNIH 738
Score = 171 bits (433), Expect = 6e-42
Identities = 140/579 (24%), Positives = 231/579 (39%), Gaps = 76/579 (13%)
Query: 220 TGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEV 279
T + F+C++ K F++ + +HTG K C C +F L H +R+H+ V
Sbjct: 71 TPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQH-RRIHTRV 129
Query: 280 KNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTE 339
+Y C EC F +L H ++H G A ++ Q T
Sbjct: 130 N---SYKCEECGKAFNWFSTLTKH-KRIHTGEKPYKCEECGKAFNQSS--------QLTR 177
Query: 340 AQATSASSQPSS-QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALE 398
+ +P+ + +Q L+ + +G+ P ++ + + Q +
Sbjct: 178 HKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKIL 237
Query: 399 NSG---------------LSSIP--AAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
++G S++ H + + A N S+++ ++ T
Sbjct: 238 HTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNIS-SNLNKQEKIHTG 296
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
+ K +E + ++ K KK + EE + C C K F + S L RH
Sbjct: 297 GKLNKCEECDKAFNRSLKLTAHKK------ILMEEKPYK---CEECGKVFNQFSTLTRHK 347
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
IHT EKP+KC +C +AF S LT H K HT K++KC+ C K+F+ +L H ++++
Sbjct: 348 IIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYS 407
Query: 562 GVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQ 621
G +P+ C C K F S H +K+ KP K D
Sbjct: 408 GEKPYKCEECGKAFNRSSTLTRH----------KKIHTGEKPYKCE-------ECDRAFS 450
Query: 622 EPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTG 681
+ +T+ + ++ ++PYKC C +A+ + L +H R HTG
Sbjct: 451 QSSNLTE------------------HKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTG 492
Query: 682 EKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPY 741
EKP+KC +CG+ F + L H HT K KC AF H IH +PY
Sbjct: 493 EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPY 552
Query: 742 MCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI 780
C K F S N H E + ++H +A ++
Sbjct: 553 KCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNL 591
Score = 168 bits (425), Expect = 5e-41
Identities = 106/345 (30%), Positives = 153/345 (44%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F +SS+L +H + HT EK YKC+ CG+ F L +H K ++G K +
Sbjct: 354 KPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYK 413
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVP------- 1077
C C +F + +LTRH H KPYKC C+ F + + +H K H
Sbjct: 414 CEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEEC 473
Query: 1078 -------SAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE---ETAQLAKIR 1127
S ++ G+ + EE N S + I T+E + + K
Sbjct: 474 GKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAF 533
Query: 1128 PQESATVSEKVLVQSAAEKDRISELRDK---QAELQDEPK--HANCCTY----CPKSFKK 1178
Q S K++ EK E K Q+ K H Y K+F
Sbjct: 534 KQSSHRTIHKII--HTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNL 591
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S++ H I+TGEKP+KC+ECGK++ S L H + HTG+K + C C AF+ +L
Sbjct: 592 FSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTL 651
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HTG KP+KC C F S H + H P K +
Sbjct: 652 NRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEE 696
Score = 166 bits (421), Expect = 1e-40
Identities = 108/345 (31%), Positives = 144/345 (41%), Gaps = 60/345 (17%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C C K F S+L H R H GEKPYKCK CGR F S L EK HTG K C
Sbjct: 244 YKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCE 303
Query: 1027 VCNASFTTN----------------------------GSLTRHMATHMSMKPYKCPFCEE 1058
C+ +F + +LTRH H KPYKC C +
Sbjct: 304 ECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGK 363
Query: 1059 GFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE 1118
F + + +H K H S + C + +HS+ RK + E
Sbjct: 364 AFNQSSNLTEHKKIHTAEKSYKC--------EECGKAFNQHSNLINHRKIYSGEKPYKCE 415
Query: 1119 ETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
E + S+T++ R K+ ++P C C ++F +
Sbjct: 416 ECGKAF----NRSSTLT-----------------RHKKIHTGEKPYK---CEECDRAFSQ 451
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S+L H +IHTGEKPYKC+ECGK+F STL H + HTG+K + C C AF+ L
Sbjct: 452 SSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQL 511
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HT K KC F+ S R H H P K +
Sbjct: 512 TRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEE 556
Score = 163 bits (412), Expect = 2e-39
Identities = 98/344 (28%), Positives = 151/344 (43%), Gaps = 54/344 (15%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C++ F +SS+L +H + HTGEKPYKC+ CG+ F L H++ HTG K +
Sbjct: 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK 497
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVH---------------CKKH 1069
C C +F + LTRH H K KC + F+ + H C++H
Sbjct: 498 CEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEH 557
Query: 1070 MKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKI--- 1126
K S ++ G+ + EE N I +T E+ + +
Sbjct: 558 GKVFNQ-SSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKA 616
Query: 1127 -----------------RPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC- 1168
+P + A + S + +I +K + ++ K N
Sbjct: 617 YNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLS 676
Query: 1169 -----------------CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
C C K+F + S+L H +IHT EKPYKC+ECGKSF S+L+
Sbjct: 677 STLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLN 736
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
H HTG+K + C AF+ +L H ++HTG KP+KC +
Sbjct: 737 IHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY 780
Score = 159 bits (402), Expect = 2e-38
Identities = 98/325 (30%), Positives = 148/325 (45%), Gaps = 23/325 (7%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + C C+K F S L +H RIHT +KC +C +AF STLT H + HT
Sbjct: 96 RRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT 155
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH----- 588
G K +KC+ C K+F+ S L H +HT +P C C K F+ + H H H
Sbjct: 156 GEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKP 215
Query: 589 FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQ---FFQSYF 645
+K+ E K+ Q + IL T L + + F +
Sbjct: 216 YKYEECGKVFSQSSHLTT---------------QKILHTGENLYKCKECGKAFNLFSNLT 260
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
N+ ++ ++PYKC C RA+ S +L + + HTG K KC +C + F + L AH +
Sbjct: 261 NHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKK 320
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY 765
K +KC C F +L RH IH +PY C C K F S N +H K H
Sbjct: 321 ILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 766 ELAQQLQQHQQAASIDDSTVDQQSM 790
E + + ++ +A + + ++ + +
Sbjct: 381 EKSYKCEECGKAFNQHSNLINHRKI 405
Score = 152 bits (384), Expect = 3e-36
Identities = 94/319 (29%), Positives = 138/319 (43%), Gaps = 36/319 (11%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
++C+ K F K S+ ++ R HTG K +KCK C + F L H + HT V ++ C
Sbjct: 76 FQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCE 135
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F +LT+H H KPYKC C + F + +H H
Sbjct: 136 ECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH-----------TE 184
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVLVQSAA 1144
E + C EE + + AS + ++I E+ + + K+ Q S ++K+L
Sbjct: 185 EKPNKC--EECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKIL----- 237
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
++ C C K+F S+L H RIH GEKPYKC ECG++F
Sbjct: 238 ----------------HTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAF 281
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
+ S L+ K HTG KL C C AF+ L H ++ KP+KC C F
Sbjct: 282 NISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFS 341
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H H P K ++
Sbjct: 342 TLTRHKIIHTGEKPYKCKE 360
Score = 121 bits (303), Expect = 7e-27
Identities = 60/148 (40%), Positives = 90/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF + ++L H + +
Sbjct: 354 KPYKCKECGKAFNQSSNLTEH-KKIHTAEKSYKCEECGKAFNQHSNLINHRKIY------ 406
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C KAF + S L RH +IHTGE+P+ C C++AF+Q S L H K HTG
Sbjct: 407 SGEKP--YKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTG 464
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F + S + H KR H+
Sbjct: 465 EKPYKCEECGKAFNRFSTLTKH-KRIHT 491
Score = 120 bits (302), Expect = 9e-27
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 15/186 (8%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + ++++C EC +AF+ + L++H K ++ E+ + C C KAF R++
Sbjct: 368 SSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRK-IYSGEKPYKCEECGKAFNRSST 426
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C++AF++ S L H +IHTGE+P+ C C KAFN
Sbjct: 427 LTRHKKIH------TGEKP--YKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFN 478
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEE 1820
+ S L H + HTGE+PYKC C F Q + H K H+ +E E+ G+
Sbjct: 479 RFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRH-KIVHT-----KEKLNKCEEFGKA 532
Query: 1821 LSRTLH 1826
++ H
Sbjct: 533 FKQSSH 538
Score = 117 bits (292), Expect = 1e-25
Identities = 66/196 (33%), Positives = 96/196 (48%), Gaps = 36/196 (18%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHS------------- 1676
C+E + +S NL + G+ ++C ECD+AF+ + L H
Sbjct: 274 CKECG-RAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEE 332
Query: 1677 --------------KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVF 1722
K +H E+ + C C KAF ++++L EH + H A S +
Sbjct: 333 CGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKS--------Y 384
Query: 1723 KCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAY 1782
KC+ C KAF + S L H +I++GE+P+ C C KAFN+ S L H K HTGE+PYKC
Sbjct: 385 KCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEE 444
Query: 1783 CVMGFTQKSNMKLHMK 1798
C F+Q SN+ H K
Sbjct: 445 CDRAFSQSSNLTEHKK 460
Score = 114 bits (285), Expect = 9e-25
Identities = 57/144 (39%), Positives = 82/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ +QC EC +AF+ ++ L H K +H E+ + C C KAF ++ L H + H
Sbjct: 634 KPYQCAECGKAFNCSSTLNRH-KIIHTGEKPYKCKECGKAFNLSSTLTAHKKIH------ 686
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF + S L H +IHT E+P+ C C K+FNQ S+L +H HTG
Sbjct: 687 TGEKP--YKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTG 744
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC F SN+ H K
Sbjct: 745 EKPYKCGDYGRAFNLSSNLTTHKK 768
Score = 114 bits (284), Expect = 1e-24
Identities = 58/142 (40%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ H+C EC +A++ + L H K +H E+ + C C KAF ++ L H H
Sbjct: 606 KPHKCEECGKAYNRFSNLTIH-KRIHTGEKPYQCAECGKAFNCSSTLNRHKIIH------ 658
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF S L H +IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 659 TGEKP--YKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTS 716
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F Q S++ +H
Sbjct: 717 EKPYKCEECGKSFNQFSSLNIH 738
Score = 109 bits (273), Expect = 2e-23
Identities = 59/144 (40%), Positives = 79/144 (54%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC RAF+ ++ L K +H +++ C C KAF R+ L H + L
Sbjct: 270 KPYKCKECGRAFNISSNLNKQEK-IHTGGKLNKCEECDKAFNRSLKLTAHKKI------L 322
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP +KC+ C K F + S L RH IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 323 MEEKP--YKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+ YKC C F Q SN+ H K
Sbjct: 381 EKSYKCEECGKAFNQHSNLINHRK 404
Score = 108 bits (269), Expect = 6e-23
Identities = 64/169 (37%), Positives = 87/169 (51%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V S NL ++ E +AF+ + + +H K ++ E+ H C
Sbjct: 554 CEEHG-KVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNH-KIIYTGEKPHKCE 611
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KA+ R ++L H + H + +KP ++C C KAF S L RH IHTGE+P
Sbjct: 612 ECGKAYNRFSNLTIHKRIH------TGEKP--YQCAECGKAFNCSSTLNRHKIIHTGEKP 663
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C C KAFN S L H K HTGE+PYKC C F Q SN+ H K
Sbjct: 664 YKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKK 712
Score = 107 bits (266), Expect = 1e-22
Identities = 62/176 (35%), Positives = 93/176 (52%), Gaps = 11/176 (6%)
Query: 1621 HTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVH 1680
HT + S CEE + NL + + ++C EC +AF+ ++ L H K++H
Sbjct: 378 HTAEK-SYKCEECG-KAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRH-KKIH 434
Query: 1681 GRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERH 1740
E+ + C C +AF ++++L EH + H + +KP +KC+ C KAF + S L +H
Sbjct: 435 TGEKPYKCEECDRAFSQSSNLTEHKKIH------TGEKP--YKCEECGKAFNRFSTLTKH 486
Query: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
RIHTGE+P+ C C KAFNQ L H HT E+ KC F Q S+ +H
Sbjct: 487 KRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIH 542
Score = 104 bits (259), Expect = 9e-22
Identities = 52/128 (40%), Positives = 78/128 (60%), Gaps = 9/128 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF ++++L H + H
Sbjct: 662 KPYKCKECGKAFNLSSTLTAH-KKIHTGEKPYKCEECGKAFNQSSNLTTHKKIH------ 714
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+S+KP +KC+ C K+F + S L H IHTGE+P+ C +AFN S L H K HTG
Sbjct: 715 TSEKP--YKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTG 772
Query: 1775 ERPYKCAY 1782
E+PYKC Y
Sbjct: 773 EKPYKCEY 780
Score = 98.6 bits (244), Expect = 5e-20
Identities = 56/147 (38%), Positives = 77/147 (52%), Gaps = 10/147 (6%)
Query: 1656 AHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLS 1715
+++C EC +AF+ + L H K +H E+ + C C KAF +++ L H H +
Sbjct: 131 SYKCEECGKAFNWFSTLTKH-KRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH------T 183
Query: 1716 SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
+KP KC+ C KAF + S L H IHTGE+P+ C K F+Q S L HTGE
Sbjct: 184 EEKPN--KCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGE 241
Query: 1776 RPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C F SN+ H KR H+
Sbjct: 242 NLYKCKECGKAFNLFSNLTNH-KRIHA 267
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 21/164 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQA---- 1710
+ ++C EC +AF+ ++ L H K +H E+ + C C KAFK+A+HL H H
Sbjct: 158 KPYKCEECGKAFNQSSQLTRH-KIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPY 216
Query: 1711 -----------GPSLSSQK-----PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
L++QK ++KC C KAF S L H RIH GE+P+ C
Sbjct: 217 KYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKE 276
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
C +AFN S L K HTG + KC C F + + H K
Sbjct: 277 CGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKK 320
Score = 89.0 bits (219), Expect = 4e-17
Identities = 55/151 (36%), Positives = 74/151 (49%), Gaps = 14/151 (9%)
Query: 1677 KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQ 1736
K H + C C K+F + L +H + H S +KC+ C KAF S
Sbjct: 95 KRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNS--------YKCEECGKAFNWFST 146
Query: 1737 LERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
L +H RIHTGE+P+ C C KAFNQ S L H HT E+P KC C F Q S++ +H
Sbjct: 147 LTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIH 206
Query: 1797 MKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
K H+ E E+ G+ S++ HL
Sbjct: 207 -KIIHT-----GEKPYKYEECGKVFSQSSHL 231
Score = 87.0 bits (214), Expect = 1e-16
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 66/204 (32%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C ECDRAFS ++ L H K++H E+ + C C KAF R + L +H + H
Sbjct: 438 KPYKCEECDRAFSQSSNLTEH-KKIHTGEKPYKCEECGKAFNRFSTLTKHKRIH------ 490
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSR----------------------------IHTG 1746
+ +KP +KC+ C KAF + QL RH IHTG
Sbjct: 491 TGEKP--YKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTG 548
Query: 1747 ERPFHCTLCEKAFNQKSALQV----------------------------HMKKHTGERPY 1778
E+P+ C K FNQ S L H +TGE+P+
Sbjct: 549 EKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPH 608
Query: 1779 KCAYCVMGFTQKSNMKLHMKRAHS 1802
KC C + + SN+ +H KR H+
Sbjct: 609 KCEECGKAYNRFSNLTIH-KRIHT 631
Score = 80.9 bits (198), Expect = 1e-14
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 647 NNFVNEA--DRPYKCFYCHRAYK---KSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+N VN+ P K F C++ K K + ++ R HTG K FKC +C + F L
Sbjct: 61 HNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H R HT + S+KC C AF +L +H IH +PY C C K F S +H
Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKI 180
Query: 762 THRYELAQQLQQ 773
H E + ++
Sbjct: 181 IHTEEKPNKCEE 192
Score = 65.9 bits (159), Expect = 4e-10
Identities = 30/63 (47%), Positives = 37/63 (58%)
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
S + Y+C+ C K F + S L H HTGEKPYKC GR F S L +H+K HTG K
Sbjct: 716 SEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775
Query: 1023 FSC 1025
+ C
Sbjct: 776 YKC 778
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/165 (28%), Positives = 63/165 (38%), Gaps = 35/165 (21%)
Query: 1692 RKAFKRATHLKEHMQTHQA-GPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
RK K H H L++ ++F+C+ K F K S R+ R HTG + F
Sbjct: 45 RKGCKHVDECTGHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHF 104
Query: 1751 HCTLCE----------------------------KAFNQKSALQVHMKKHTGERPYKCAY 1782
C C KAFN S L H + HTGE+PYKC
Sbjct: 105 KCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEE 164
Query: 1783 CVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
C F Q S + H K H+ +E E+ G+ + HL
Sbjct: 165 CGKAFNQSSQLTRH-KIIHT-----EEKPNKCEECGKAFKQASHL 203
Score = 58.5 bits (140), Expect = 6e-08
Identities = 36/136 (26%), Positives = 54/136 (39%), Gaps = 4/136 (2%)
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
R + + +L+ KH + CT K + V T K ++C++ K F
Sbjct: 33 RYGKCEYENLQLRKGCKHVDECT----GHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKF 88
Query: 1208 STLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRK 1267
S + + + HTG K F C CS +F L H R+HT +KC C F
Sbjct: 89 SNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLT 148
Query: 1268 THMQFHYKPDPKKARK 1283
H + H P K +
Sbjct: 149 KHKRIHTGEKPYKCEE 164
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + + ++C EC ++F+ + L H K +H E+ + C
Sbjct: 694 CEECG-KAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIH-KIIHTGEKPYKCG 751
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCD 1725
+AF +++L H + H + +KP +KC+
Sbjct: 752 DYGRAFNLSSNLTTHKKIH------TGEKP--YKCE 779
>gi|7706775 zinc finger protein 107 [Homo sapiens]
Length = 783
Score = 295 bits (754), Expect = 4e-79
Identities = 203/710 (28%), Positives = 305/710 (42%), Gaps = 73/710 (10%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLI 122
K +C++ + F+ N +K H+G C C+K F ++ L H +H + +
Sbjct: 74 KIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYK 133
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182
C ECG F S L H H G + + C+ C K F SS+L H H + + +
Sbjct: 134 CEECGKAFNWFSTLTKHKRIH----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNK 189
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
C CGK F++ S LT H IHTGE+P+K ECGK F+Q L T
Sbjct: 190 ----------------CEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTT 233
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
I HTGE + C C AF+ NL +H +R+H+ K Y C EC F +LN
Sbjct: 234 QKILHTGENLYKCKECGKAFNLFSNLTNH-KRIHAGEK---PYKCKECGRAFNISSNLNK 289
Query: 303 HISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQL 361
K+H GG N + A L+ T + +P + V Q
Sbjct: 290 Q-EKIHTGGKLNKCEECDKAF--------NRSLKLTAHKKILMEEKPYKCEECGKVFNQF 340
Query: 362 LELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAK--T 419
L+ + +G+ P ++ + ++ + H K T
Sbjct: 341 STLTRHKIIHTGEKPYKCKECGKAFNQSSNLTE---------------------HKKIHT 379
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
+ + + N+ ++ + + E P K ++ K +S L + G
Sbjct: 380 AEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAF--NRSSTLTRHKKIHTGE 437
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
+ + C C + F + S+L H +IHT EKP+KC +C +AF STLT H + HTG K +K
Sbjct: 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK 497
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRH 599
C+ C K+F+ S L H +HT + C K F+ S HR H H + H
Sbjct: 498 CEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEH 557
Query: 600 QRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQ---FFQSYFNNNFVNEADRP 656
KV +N+ + I+ T L + + F + N+ + ++P
Sbjct: 558 ----GKVFNQSSNLTT------QKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKP 607
Query: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716
+KC C +AY + +L H R HTGEKP++C++CG+ F + L H HTG K +KC
Sbjct: 608 HKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCK 667
Query: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
C AF +L H IH +PY C C K F S N H K H E
Sbjct: 668 ECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSE 717
Score = 283 bits (724), Expect = 1e-75
Identities = 203/680 (29%), Positives = 304/680 (44%), Gaps = 90/680 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + SQ RH H +KP++C++C + F +LT+HK H+GE P
Sbjct: 160 YKCEECGKAFNQSSQLTRHKIIH-TEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKY 218
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS+ + L +LH E C ECG F L S L H H AG + + C
Sbjct: 219 EECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIH----AGEKPYKC 274
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSS----TRSYNRNIDRSGF--------TYSCPHCG 203
K C + F SS L + K H +++ +++NR++ + Y C CG
Sbjct: 275 KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECG 334
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F + S LTRH IHTGE+P+KC ECGKAFNQ L H HT EK + C C AF+
Sbjct: 335 KVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFN 394
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAH 323
Q NL +H ++++S K Y C EC F +L H K+H G + A
Sbjct: 395 QHSNLINH-RKIYSGEK---PYKCEECGKAFNRSSTLTRH-KKIHTGEKPYKCEECDRAF 449
Query: 324 VLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQL 382
++ L TE + +P + + L++ + +G+ P ++
Sbjct: 450 SQSSNL--------TEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEEC 501
Query: 383 SITVGINQDILQQAL----------ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSV 432
+ + + + E G + ++H T + + V
Sbjct: 502 GKAFNQSYQLTRHKIVHTKEKLNKCEEFG-KAFKQSSHRTIHKIIHTGEKPYKCEEHGKV 560
Query: 433 SNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREE----NGVRWHVCPYCA 488
N+ ++ T +K + E L K E+ K+ L +I G + H C C
Sbjct: 561 FNQSSNLT---TQKIIHTGENLYKFEE---HGKAFNLFSNITNHKIIYTGEKPHKCEECG 614
Query: 489 KEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 548
K + + S+L H RIHT EKP++C +C +AF STL H HTG K +KC+ C K+F+
Sbjct: 615 KAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFN 674
Query: 549 TSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-R 607
S +L H ++HTG +P+ C C K F S + TH +K+ KP K
Sbjct: 675 LSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH----------KKIHTSEKPYKCEE 724
Query: 608 VGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYK 667
GK+ NQ F S + ++ ++PYKC RA+
Sbjct: 725 CGKS-------------------------FNQ-FSSLNIHKIIHTGEKPYKCGDYGRAFN 758
Query: 668 KSCHLKQHIRSHTGEKPFKC 687
S +L H + HTGEKP+KC
Sbjct: 759 LSSNLTTHKKIHTGEKPYKC 778
Score = 270 bits (689), Expect = 1e-71
Identities = 202/720 (28%), Positives = 293/720 (40%), Gaps = 109/720 (15%)
Query: 98 CNKK---FSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHA 154
CNK F + ++ + H ++ C EC F + SQL H H + +
Sbjct: 78 CNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR----VNSYK 133
Query: 155 CKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTR 214
C+ C K F S L +H + H + Y C CGK F + SQLTR
Sbjct: 134 CEECGKAFNWFSTLTKHKRIHTGEK----------------PYKCEECGKAFNQSSQLTR 177
Query: 215 HIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQR 274
H IHT E+P KC ECGKAF Q L H I HTGEKP+ C FSQ +L + Q+
Sbjct: 178 HKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTT--QK 235
Query: 275 VHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLP 334
+ +N Y C EC F +L H ++H G A +++ L
Sbjct: 236 ILHTGEN--LYKCKECGKAFNLFSNLTNH-KRIHAGEKPYKCKECGRAFNISSNL----- 287
Query: 335 LQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
+ + + + + L+L+ + + P ++ + +
Sbjct: 288 --NKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTR 345
Query: 395 QALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
+ H + + A N SS E AE+ + E K
Sbjct: 346 HKI-----------IHTGEKPYKCKECGKAFNQ--SSNLTEHKKIHTAEKSYKCEECGKA 392
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ +I + + +G + + C C K F + S L RH +IHT EKP+KC +
Sbjct: 393 FNQHSNLINHRKIY--------SGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEE 444
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C RAF+ S LT H K HTG K +KC+ C K+F+ +L H R+HTG +P+ C C K
Sbjct: 445 CDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKA 504
Query: 575 FRTSGHRKTHIASHFK-----------------HTELRKMRHQ-RKPAKVRV-GKTNIPV 615
F S H H K H + K+ H KP K GK
Sbjct: 505 FNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQS 564
Query: 616 PDIPLQEPILITDLGLIQPIPKNQFFQSYFN-----------------------NNFVN- 651
++ Q+ I+ T L + + F + N N F N
Sbjct: 565 SNLTTQK-IIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNL 623
Query: 652 -------EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHI 704
++PY+C C +A+ S L +H HTGEKP+KC +CG+ F + L AH
Sbjct: 624 TIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHK 683
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFK--TSLNCKKHMKT 762
+ HTG K +KC C AF +L H IH +PY C C K+F +SLN K + T
Sbjct: 684 KIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHT 743
Score = 258 bits (658), Expect = 5e-68
Identities = 182/605 (30%), Positives = 262/605 (43%), Gaps = 91/605 (15%)
Query: 35 NFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPT 94
N +KC+ C +F S H R H +KP++C +C + FN+ NL + H+G
Sbjct: 242 NLYKCKECGKAFNLFSNLTNHKRIHA-GEKPYKCKECGRAFNISSNLNKQEKIHTGGKLN 300
Query: 95 -CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQH 153
C C+K F+R L AH + +E+ C ECG F S L H H G + +
Sbjct: 301 KCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIH----TGEKPY 356
Query: 154 ACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLT 213
CK C K F SS L EH K H + +Y C CGK F + S L
Sbjct: 357 KCKECGKAFNQSSNLTEHKKIHTAEK----------------SYKCEECGKAFNQHSNLI 400
Query: 214 RHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQ 273
H +I++GE+P+KC ECGKAFN+ L H HTGEKP+ C C AFSQ NL H +
Sbjct: 401 NHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEH-K 459
Query: 274 RVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG---------GPQNSTSSTETAHV 324
++H+ K Y C EC F +L H ++H G G + S T H
Sbjct: 460 KIHTGEK---PYKCEECGKAFNRFSTLTKH-KRIHTGEKPYKCEECGKAFNQSYQLTRHK 515
Query: 325 LTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSI 384
+ T + L + E + A Q S + + +I +G+ P ++
Sbjct: 516 IVHTKEK---LNKCE-EFGKAFKQSSHRTIHKII------------HTGEKPYKCEEHGK 559
Query: 385 TVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQ 444
+ ++ Q + ++G + H A N S+++N + T +
Sbjct: 560 VFNQSSNLTTQKIIHTGENLYKFEEHGK-----------AFNL-FSNITNHKIIYTGEKP 607
Query: 445 EKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIH 504
K +E + ++ I K R G + + C C K F S L RH IH
Sbjct: 608 HKCEECGKAYNRFSNLTIHK---------RIHTGEKPYQCAECGKAFNCSSTLNRHKIIH 658
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVR 564
T EKP+KC +C +AF + STLTAH K HTG K +KC+ C K+F+ S +L H ++HT +
Sbjct: 659 TGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEK 718
Query: 565 PFACPHCDKKFRTSGHRKTHIASHFKH------------------TELRKMRHQRKPAKV 606
P+ C C K F H H T +K+ KP K
Sbjct: 719 PYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYKC 778
Query: 607 RVGKT 611
GKT
Sbjct: 779 EYGKT 783
Score = 238 bits (607), Expect = 4e-62
Identities = 189/776 (24%), Positives = 300/776 (38%), Gaps = 93/776 (11%)
Query: 531 THTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF----RTSGHRKTHI- 585
T T K F+C +K F + + R HTG + F C C K F + + HR+ H
Sbjct: 69 TATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTR 128
Query: 586 ASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
+ +K E K + +F +
Sbjct: 129 VNSYKCEECGKAFN----------------------------------------WFSTLT 148
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
+ ++ ++PYKC C +A+ +S L +H HT EKP KC +CG+ F A L H
Sbjct: 149 KHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKI 208
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY 765
HTG K +K C F+ L +H Y C C K F N H + H
Sbjct: 209 IHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAG 268
Query: 766 ELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQ 825
E + ++ +A +I + Q+ + ++ E D+ + + A+ + +++ +P
Sbjct: 269 EKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPY 328
Query: 826 HVVGTEEAG--LGQ----------QLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQ 873
EE G Q ++P + E G Q ++ + ++ A++
Sbjct: 329 K---CEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQS---SNLTEHKKIHTAEK 382
Query: 874 SFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNV 933
S++ + F + + + +F++ S L
Sbjct: 383 SYKCEECGKAFNQHSNLINHRKI-----YSGEKPYKCEECGKAFNRSSTLTRHKKIHTGE 437
Query: 934 TTRLIQESSQEELDLQAQGSQFLEDNE-DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGE 992
+E + +Q S E + + Y+C+ C K F + S L +H R HTGE
Sbjct: 438 KPYKCEECDR----AFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGE 493
Query: 993 KPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYK 1052
KPYKC+ CG+ F S L H+ HT K C +F + T H H KPYK
Sbjct: 494 KPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYK 553
Query: 1053 CP-----FCEEGFRTT---VHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNA 1104
C F + TT +H +++ + + A + I E+ H
Sbjct: 554 CEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEEC 613
Query: 1105 SRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPK 1164
K+ T + + +P + A + S + +I +K +
Sbjct: 614 G-KAYNRFSNLTIHKRIHTGE-KPYQCAECGKAFNCSSTLNRHKIIHTGEKPYK------ 665
Query: 1165 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFS 1224
C C K+F S L H +IHTGEKPYKC+ECGK+F S L H K HT +K +
Sbjct: 666 ----CKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYK 721
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK 1280
C C +F+ SL +H +HTG KP+KC F S TH + H P K
Sbjct: 722 CEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYK 777
Score = 218 bits (554), Expect = 6e-56
Identities = 166/651 (25%), Positives = 265/651 (40%), Gaps = 92/651 (14%)
Query: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACA 256
+ C C K+F SQLT+H RIHT +KC ECGKAFN L H HTGEKP+ C
Sbjct: 104 FKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCE 163
Query: 257 FCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNST 316
C AF+Q L H + +H+E K C EC FK L H +H G
Sbjct: 164 ECGKAFNQSSQLTRH-KIIHTEEKPN---KCEECGKAFKQASHLTIH-KIIHTGEKPYKY 218
Query: 317 SS-----TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVE 371
++++H+ T + T + + L+ +
Sbjct: 219 EECGKVFSQSSHLTTQKILHT------------GENLYKCKECGKAFNLFSNLTNHKRIH 266
Query: 372 SGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSS 431
+G+ P ++ I+ ++ +Q ++G + + C
Sbjct: 267 AGEKPYKCKECGRAFNISSNLNKQEKIHTG-----GKLNKCEEC--------------DK 307
Query: 432 VSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEF 491
N T ++ +E P K ++ K + + L G + + C C K F
Sbjct: 308 AFNRSLKLTAHKKILMEEKPYKCEECGK--VFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365
Query: 492 RKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSG 551
+ S+L H +IHT EK +KC +C +AF S L H K ++G K +KC+ C K+F+ S
Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425
Query: 552 SLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH-FKHTELRKMRHQ----RK 602
+L H ++HTG +P+ C CD+ F S H+K H +K E K ++ K
Sbjct: 426 TLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTK 485
Query: 603 PAKVRVGKTNIPVPDI--PLQEPILITDLGLI---QPIPKNQFFQSYFN-------NNFV 650
++ G+ + + +T ++ + + K + F F + +
Sbjct: 486 HKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKII 545
Query: 651 NEADRPYKC------------------------FYCHRAYKKSCHLKQHIRSH----TGE 682
+ ++PYKC Y + K+ +L +I +H TGE
Sbjct: 546 HTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGE 605
Query: 683 KPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYM 742
KP KC +CG+ + L H R HTG K ++C C AF +L RH IH +PY
Sbjct: 606 KPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYK 665
Query: 743 CPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQAS 793
C C K F S H K H E + ++ +A + + + + S
Sbjct: 666 CKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTS 716
Score = 199 bits (507), Expect = 2e-50
Identities = 109/330 (33%), Positives = 161/330 (48%), Gaps = 26/330 (7%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS L +H + HTGEKPYKC+ C R F S L H+K HTG K +
Sbjct: 410 KPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYK 469
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F +LT+H H KPYKC C + F + +H H
Sbjct: 470 CEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTK--------- 520
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVL--- 1139
E + C EE + + +S ++ ++I E+ + + K+ Q S ++K++
Sbjct: 521 --EKLNKC--EEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTG 576
Query: 1140 ------VQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEK 1193
+ + S + + + E H C C K++ + S+L H RIHTGEK
Sbjct: 577 ENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHK--CEECGKAYNRFSNLTIHKRIHTGEK 634
Query: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKC 1253
PY+C ECGK+F STL+ H HTG+K + C C AF+ +L H ++HTG KP+KC
Sbjct: 635 PYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKC 694
Query: 1254 PHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C F S TH + H P K +
Sbjct: 695 EECGKAFNQSSNLTTHKKIHTSEKPYKCEE 724
Score = 184 bits (466), Expect = 9e-46
Identities = 160/630 (25%), Positives = 239/630 (37%), Gaps = 105/630 (16%)
Query: 658 KCFYCHRAYKKSCHLKQHIRSHTG-------------EKPFKCSQCGRGFVSAGVLKAHI 704
KC Y + +K C H G K F+C++ + F +
Sbjct: 36 KCEYENLQLRKGCKHVDECTGHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYK 95
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR 764
R HTG K FKC C+ +F L +H IH + Y C C K F KH + H
Sbjct: 96 RRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT 155
Query: 765 YELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEP 824
E + ++ +A + QS Q T+ ++ I ++E P E + L
Sbjct: 156 GEKPYKCEECGKAFN--------QSSQL-TRHKI-IHTEEKPNKCEECGKAFKQASHLTI 205
Query: 825 QHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGF 884
++ T E +P + +E G V Q H+ + + ++ + F
Sbjct: 206 HKIIHTGE---------KPYKYEECGKVFSQS---SHLTTQKILHTGENLYKCKECGKAF 253
Query: 885 TVTDTYHQQPQFPPVQQLQDSSTL-ESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQ 943
+ + ++ + +S++ ++Q + + G ++
Sbjct: 254 NLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIH---TGGKLNKCEECDKAFN 310
Query: 944 EELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRG 1003
L L A +E+ + Y+C+ C K F + S L +H HTGEKPYKCK CG+
Sbjct: 311 RSLKLTAHKKILMEE------KPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKA 364
Query: 1004 FVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTT 1063
F S L H+K HT K++ C C +F + +L H + KPYKC C + F +
Sbjct: 365 FNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRS 424
Query: 1064 VHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQL 1123
+H K H TGE + E DR S+ S TE +
Sbjct: 425 STLTRHKKIH---------TGE-------KPYKCEECDRAFSQSS-----NLTEHK---- 459
Query: 1124 AKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLV 1183
KI E E+ C K+F + S L
Sbjct: 460 -KIHTGEKPYKCEE----------------------------------CGKAFNRFSTLT 484
Query: 1184 RHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMR 1243
+H RIHTGEKPYKC+ECGK+F L H HT +KL C AF +H
Sbjct: 485 KHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKI 544
Query: 1244 LHTGAKPFKCPHCELRFRTSGRRKTHMQFH 1273
+HTG KP+KC F S T H
Sbjct: 545 IHTGEKPYKCEEHGKVFNQSSNLTTQKIIH 574
Score = 184 bits (466), Expect = 9e-46
Identities = 103/325 (31%), Positives = 154/325 (47%), Gaps = 22/325 (6%)
Query: 968 RCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSV 1027
+C+ C K FK++SHL H HTGEKPYK + CG+ F S L + + HTG + C
Sbjct: 189 KCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKE 248
Query: 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETE 1087
C +F +LT H H KPYKC C F + + K K H
Sbjct: 249 CGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIH-------------T 295
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVL--VQSA 1143
GG + EE + + + + + + I E+ + + K+ Q S K++ +
Sbjct: 296 GGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKP 355
Query: 1144 AEKDRISELRDKQAELQDEPK-----HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
+ + ++ + L + K + C C K+F + S+L+ H +I++GEKPYKC+
Sbjct: 356 YKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCE 415
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+F STL H K HTG+K + C C AFS +L H ++HTG KP+KC C
Sbjct: 416 ECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGK 475
Query: 1259 RFRTSGRRKTHMQFHYKPDPKKARK 1283
F H + H P K +
Sbjct: 476 AFNRFSTLTKHKRIHTGEKPYKCEE 500
Score = 173 bits (438), Expect = 2e-42
Identities = 114/346 (32%), Positives = 150/346 (43%), Gaps = 70/346 (20%)
Query: 23 NAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLT 82
N N Y +KCE C +F + S RH + H +KP++C++C + F+ NLT
Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIH-TGEKPYKCEECDRAFSQSSNLT 456
Query: 83 LHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHME 141
HK H+GE P C C K F+R ++L H +H E+ C ECG F QL H
Sbjct: 457 EHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKI 516
Query: 142 EHRQEL------------------------AGTRQHACKACKKEFETSSEL--------- 168
H +E G + + C+ K F SS L
Sbjct: 517 VHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTG 576
Query: 169 ------KEHMK--------THYKIRVSST---------RSYNR--------NIDRSGFTY 197
+EH K T++KI + ++YNR I Y
Sbjct: 577 ENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPY 636
Query: 198 SCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAF 257
C CGK F S L RH IHTGE+P+KC ECGKAFN L H HTGEKP+ C
Sbjct: 637 QCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEE 696
Query: 258 CPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
C AF+Q NL +H +++H+ K Y C EC F SLN H
Sbjct: 697 CGKAFNQSSNLTTH-KKIHTSEK---PYKCEECGKSFNQFSSLNIH 738
Score = 171 bits (433), Expect = 6e-42
Identities = 140/579 (24%), Positives = 231/579 (39%), Gaps = 76/579 (13%)
Query: 220 TGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEV 279
T + F+C++ K F++ + +HTG K C C +F L H +R+H+ V
Sbjct: 71 TPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQH-RRIHTRV 129
Query: 280 KNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTE 339
+Y C EC F +L H ++H G A ++ Q T
Sbjct: 130 N---SYKCEECGKAFNWFSTLTKH-KRIHTGEKPYKCEECGKAFNQSS--------QLTR 177
Query: 340 AQATSASSQPSS-QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALE 398
+ +P+ + +Q L+ + +G+ P ++ + + Q +
Sbjct: 178 HKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKIL 237
Query: 399 NSG---------------LSSIP--AAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
++G S++ H + + A N S+++ ++ T
Sbjct: 238 HTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNIS-SNLNKQEKIHTG 296
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
+ K +E + ++ K KK + EE + C C K F + S L RH
Sbjct: 297 GKLNKCEECDKAFNRSLKLTAHKK------ILMEEKPYK---CEECGKVFNQFSTLTRHK 347
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
IHT EKP+KC +C +AF S LT H K HT K++KC+ C K+F+ +L H ++++
Sbjct: 348 IIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYS 407
Query: 562 GVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQ 621
G +P+ C C K F S H +K+ KP K D
Sbjct: 408 GEKPYKCEECGKAFNRSSTLTRH----------KKIHTGEKPYKCE-------ECDRAFS 450
Query: 622 EPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTG 681
+ +T+ + ++ ++PYKC C +A+ + L +H R HTG
Sbjct: 451 QSSNLTE------------------HKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTG 492
Query: 682 EKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPY 741
EKP+KC +CG+ F + L H HT K KC AF H IH +PY
Sbjct: 493 EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPY 552
Query: 742 MCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI 780
C K F S N H E + ++H +A ++
Sbjct: 553 KCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNL 591
Score = 168 bits (425), Expect = 5e-41
Identities = 106/345 (30%), Positives = 153/345 (44%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F +SS+L +H + HT EK YKC+ CG+ F L +H K ++G K +
Sbjct: 354 KPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYK 413
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVP------- 1077
C C +F + +LTRH H KPYKC C+ F + + +H K H
Sbjct: 414 CEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEEC 473
Query: 1078 -------SAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE---ETAQLAKIR 1127
S ++ G+ + EE N S + I T+E + + K
Sbjct: 474 GKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAF 533
Query: 1128 PQESATVSEKVLVQSAAEKDRISELRDK---QAELQDEPK--HANCCTY----CPKSFKK 1178
Q S K++ EK E K Q+ K H Y K+F
Sbjct: 534 KQSSHRTIHKII--HTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNL 591
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S++ H I+TGEKP+KC+ECGK++ S L H + HTG+K + C C AF+ +L
Sbjct: 592 FSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTL 651
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HTG KP+KC C F S H + H P K +
Sbjct: 652 NRHKIIHTGEKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEE 696
Score = 166 bits (421), Expect = 1e-40
Identities = 108/345 (31%), Positives = 144/345 (41%), Gaps = 60/345 (17%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C C K F S+L H R H GEKPYKCK CGR F S L EK HTG K C
Sbjct: 244 YKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCE 303
Query: 1027 VCNASFTTN----------------------------GSLTRHMATHMSMKPYKCPFCEE 1058
C+ +F + +LTRH H KPYKC C +
Sbjct: 304 ECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGK 363
Query: 1059 GFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE 1118
F + + +H K H S + C + +HS+ RK + E
Sbjct: 364 AFNQSSNLTEHKKIHTAEKSYKC--------EECGKAFNQHSNLINHRKIYSGEKPYKCE 415
Query: 1119 ETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
E + S+T++ R K+ ++P C C ++F +
Sbjct: 416 ECGKAF----NRSSTLT-----------------RHKKIHTGEKPYK---CEECDRAFSQ 451
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S+L H +IHTGEKPYKC+ECGK+F STL H + HTG+K + C C AF+ L
Sbjct: 452 SSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQL 511
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HT K KC F+ S R H H P K +
Sbjct: 512 TRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEE 556
Score = 163 bits (412), Expect = 2e-39
Identities = 98/344 (28%), Positives = 151/344 (43%), Gaps = 54/344 (15%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C++ F +SS+L +H + HTGEKPYKC+ CG+ F L H++ HTG K +
Sbjct: 438 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYK 497
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVH---------------CKKH 1069
C C +F + LTRH H K KC + F+ + H C++H
Sbjct: 498 CEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEH 557
Query: 1070 MKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKI--- 1126
K S ++ G+ + EE N I +T E+ + +
Sbjct: 558 GKVFNQ-SSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKA 616
Query: 1127 -----------------RPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC- 1168
+P + A + S + +I +K + ++ K N
Sbjct: 617 YNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLS 676
Query: 1169 -----------------CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
C C K+F + S+L H +IHT EKPYKC+ECGKSF S+L+
Sbjct: 677 STLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLN 736
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
H HTG+K + C AF+ +L H ++HTG KP+KC +
Sbjct: 737 IHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY 780
Score = 159 bits (402), Expect = 2e-38
Identities = 98/325 (30%), Positives = 148/325 (45%), Gaps = 23/325 (7%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + C C+K F S L +H RIHT +KC +C +AF STLT H + HT
Sbjct: 96 RRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHT 155
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH----- 588
G K +KC+ C K+F+ S L H +HT +P C C K F+ + H H H
Sbjct: 156 GEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKP 215
Query: 589 FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQ---FFQSYF 645
+K+ E K+ Q + IL T L + + F +
Sbjct: 216 YKYEECGKVFSQSSHLTT---------------QKILHTGENLYKCKECGKAFNLFSNLT 260
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
N+ ++ ++PYKC C RA+ S +L + + HTG K KC +C + F + L AH +
Sbjct: 261 NHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKK 320
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY 765
K +KC C F +L RH IH +PY C C K F S N +H K H
Sbjct: 321 ILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 766 ELAQQLQQHQQAASIDDSTVDQQSM 790
E + + ++ +A + + ++ + +
Sbjct: 381 EKSYKCEECGKAFNQHSNLINHRKI 405
Score = 152 bits (384), Expect = 3e-36
Identities = 94/319 (29%), Positives = 138/319 (43%), Gaps = 36/319 (11%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
++C+ K F K S+ ++ R HTG K +KCK C + F L H + HT V ++ C
Sbjct: 76 FQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCE 135
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F +LT+H H KPYKC C + F + +H H
Sbjct: 136 ECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH-----------TE 184
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQESATVSEKVLVQSAA 1144
E + C EE + + AS + ++I E+ + + K+ Q S ++K+L
Sbjct: 185 EKPNKC--EECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKIL----- 237
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
++ C C K+F S+L H RIH GEKPYKC ECG++F
Sbjct: 238 ----------------HTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAF 281
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
+ S L+ K HTG KL C C AF+ L H ++ KP+KC C F
Sbjct: 282 NISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFS 341
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H H P K ++
Sbjct: 342 TLTRHKIIHTGEKPYKCKE 360
Score = 121 bits (303), Expect = 7e-27
Identities = 60/148 (40%), Positives = 90/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF + ++L H + +
Sbjct: 354 KPYKCKECGKAFNQSSNLTEH-KKIHTAEKSYKCEECGKAFNQHSNLINHRKIY------ 406
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C KAF + S L RH +IHTGE+P+ C C++AF+Q S L H K HTG
Sbjct: 407 SGEKP--YKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTG 464
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F + S + H KR H+
Sbjct: 465 EKPYKCEECGKAFNRFSTLTKH-KRIHT 491
Score = 120 bits (302), Expect = 9e-27
Identities = 64/186 (34%), Positives = 102/186 (54%), Gaps = 15/186 (8%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + ++++C EC +AF+ + L++H K ++ E+ + C C KAF R++
Sbjct: 368 SSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRK-IYSGEKPYKCEECGKAFNRSST 426
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C++AF++ S L H +IHTGE+P+ C C KAFN
Sbjct: 427 LTRHKKIH------TGEKP--YKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFN 478
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEE 1820
+ S L H + HTGE+PYKC C F Q + H K H+ +E E+ G+
Sbjct: 479 RFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRH-KIVHT-----KEKLNKCEEFGKA 532
Query: 1821 LSRTLH 1826
++ H
Sbjct: 533 FKQSSH 538
Score = 117 bits (292), Expect = 1e-25
Identities = 66/196 (33%), Positives = 96/196 (48%), Gaps = 36/196 (18%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHS------------- 1676
C+E + +S NL + G+ ++C ECD+AF+ + L H
Sbjct: 274 CKECG-RAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEE 332
Query: 1677 --------------KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVF 1722
K +H E+ + C C KAF ++++L EH + H A S +
Sbjct: 333 CGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKS--------Y 384
Query: 1723 KCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAY 1782
KC+ C KAF + S L H +I++GE+P+ C C KAFN+ S L H K HTGE+PYKC
Sbjct: 385 KCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEE 444
Query: 1783 CVMGFTQKSNMKLHMK 1798
C F+Q SN+ H K
Sbjct: 445 CDRAFSQSSNLTEHKK 460
Score = 114 bits (285), Expect = 9e-25
Identities = 57/144 (39%), Positives = 82/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ +QC EC +AF+ ++ L H K +H E+ + C C KAF ++ L H + H
Sbjct: 634 KPYQCAECGKAFNCSSTLNRH-KIIHTGEKPYKCKECGKAFNLSSTLTAHKKIH------ 686
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF + S L H +IHT E+P+ C C K+FNQ S+L +H HTG
Sbjct: 687 TGEKP--YKCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTG 744
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC F SN+ H K
Sbjct: 745 EKPYKCGDYGRAFNLSSNLTTHKK 768
Score = 114 bits (284), Expect = 1e-24
Identities = 58/142 (40%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ H+C EC +A++ + L H K +H E+ + C C KAF ++ L H H
Sbjct: 606 KPHKCEECGKAYNRFSNLTIH-KRIHTGEKPYQCAECGKAFNCSSTLNRHKIIH------ 658
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF S L H +IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 659 TGEKP--YKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTS 716
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F Q S++ +H
Sbjct: 717 EKPYKCEECGKSFNQFSSLNIH 738
Score = 109 bits (273), Expect = 2e-23
Identities = 59/144 (40%), Positives = 79/144 (54%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC RAF+ ++ L K +H +++ C C KAF R+ L H + L
Sbjct: 270 KPYKCKECGRAFNISSNLNKQEK-IHTGGKLNKCEECDKAFNRSLKLTAHKKI------L 322
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP +KC+ C K F + S L RH IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 323 MEEKP--YKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTA 380
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+ YKC C F Q SN+ H K
Sbjct: 381 EKSYKCEECGKAFNQHSNLINHRK 404
Score = 108 bits (269), Expect = 6e-23
Identities = 64/169 (37%), Positives = 87/169 (51%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V S NL ++ E +AF+ + + +H K ++ E+ H C
Sbjct: 554 CEEHG-KVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNH-KIIYTGEKPHKCE 611
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KA+ R ++L H + H + +KP ++C C KAF S L RH IHTGE+P
Sbjct: 612 ECGKAYNRFSNLTIHKRIH------TGEKP--YQCAECGKAFNCSSTLNRHKIIHTGEKP 663
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C C KAFN S L H K HTGE+PYKC C F Q SN+ H K
Sbjct: 664 YKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKK 712
Score = 107 bits (266), Expect = 1e-22
Identities = 62/176 (35%), Positives = 93/176 (52%), Gaps = 11/176 (6%)
Query: 1621 HTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVH 1680
HT + S CEE + NL + + ++C EC +AF+ ++ L H K++H
Sbjct: 378 HTAEK-SYKCEECG-KAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRH-KKIH 434
Query: 1681 GRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERH 1740
E+ + C C +AF ++++L EH + H + +KP +KC+ C KAF + S L +H
Sbjct: 435 TGEKPYKCEECDRAFSQSSNLTEHKKIH------TGEKP--YKCEECGKAFNRFSTLTKH 486
Query: 1741 SRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
RIHTGE+P+ C C KAFNQ L H HT E+ KC F Q S+ +H
Sbjct: 487 KRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIH 542
Score = 104 bits (259), Expect = 9e-22
Identities = 52/128 (40%), Positives = 78/128 (60%), Gaps = 9/128 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF ++++L H + H
Sbjct: 662 KPYKCKECGKAFNLSSTLTAH-KKIHTGEKPYKCEECGKAFNQSSNLTTHKKIH------ 714
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+S+KP +KC+ C K+F + S L H IHTGE+P+ C +AFN S L H K HTG
Sbjct: 715 TSEKP--YKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTG 772
Query: 1775 ERPYKCAY 1782
E+PYKC Y
Sbjct: 773 EKPYKCEY 780
Score = 98.6 bits (244), Expect = 5e-20
Identities = 56/147 (38%), Positives = 77/147 (52%), Gaps = 10/147 (6%)
Query: 1656 AHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLS 1715
+++C EC +AF+ + L H K +H E+ + C C KAF +++ L H H +
Sbjct: 131 SYKCEECGKAFNWFSTLTKH-KRIHTGEKPYKCEECGKAFNQSSQLTRHKIIH------T 183
Query: 1716 SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
+KP KC+ C KAF + S L H IHTGE+P+ C K F+Q S L HTGE
Sbjct: 184 EEKPN--KCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGE 241
Query: 1776 RPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C F SN+ H KR H+
Sbjct: 242 NLYKCKECGKAFNLFSNLTNH-KRIHA 267
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 21/164 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQA---- 1710
+ ++C EC +AF+ ++ L H K +H E+ + C C KAFK+A+HL H H
Sbjct: 158 KPYKCEECGKAFNQSSQLTRH-KIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPY 216
Query: 1711 -----------GPSLSSQK-----PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
L++QK ++KC C KAF S L H RIH GE+P+ C
Sbjct: 217 KYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKE 276
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
C +AFN S L K HTG + KC C F + + H K
Sbjct: 277 CGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKK 320
Score = 89.0 bits (219), Expect = 4e-17
Identities = 55/151 (36%), Positives = 74/151 (49%), Gaps = 14/151 (9%)
Query: 1677 KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQ 1736
K H + C C K+F + L +H + H S +KC+ C KAF S
Sbjct: 95 KRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNS--------YKCEECGKAFNWFST 146
Query: 1737 LERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
L +H RIHTGE+P+ C C KAFNQ S L H HT E+P KC C F Q S++ +H
Sbjct: 147 LTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIH 206
Query: 1797 MKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
K H+ E E+ G+ S++ HL
Sbjct: 207 -KIIHT-----GEKPYKYEECGKVFSQSSHL 231
Score = 87.0 bits (214), Expect = 1e-16
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 66/204 (32%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C ECDRAFS ++ L H K++H E+ + C C KAF R + L +H + H
Sbjct: 438 KPYKCEECDRAFSQSSNLTEH-KKIHTGEKPYKCEECGKAFNRFSTLTKHKRIH------ 490
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSR----------------------------IHTG 1746
+ +KP +KC+ C KAF + QL RH IHTG
Sbjct: 491 TGEKP--YKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTG 548
Query: 1747 ERPFHCTLCEKAFNQKSALQV----------------------------HMKKHTGERPY 1778
E+P+ C K FNQ S L H +TGE+P+
Sbjct: 549 EKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPH 608
Query: 1779 KCAYCVMGFTQKSNMKLHMKRAHS 1802
KC C + + SN+ +H KR H+
Sbjct: 609 KCEECGKAYNRFSNLTIH-KRIHT 631
Score = 80.9 bits (198), Expect = 1e-14
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 647 NNFVNEA--DRPYKCFYCHRAYK---KSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+N VN+ P K F C++ K K + ++ R HTG K FKC +C + F L
Sbjct: 61 HNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H R HT + S+KC C AF +L +H IH +PY C C K F S +H
Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKI 180
Query: 762 THRYELAQQLQQ 773
H E + ++
Sbjct: 181 IHTEEKPNKCEE 192
Score = 65.9 bits (159), Expect = 4e-10
Identities = 30/63 (47%), Positives = 37/63 (58%)
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
S + Y+C+ C K F + S L H HTGEKPYKC GR F S L +H+K HTG K
Sbjct: 716 SEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775
Query: 1023 FSC 1025
+ C
Sbjct: 776 YKC 778
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/165 (28%), Positives = 63/165 (38%), Gaps = 35/165 (21%)
Query: 1692 RKAFKRATHLKEHMQTHQA-GPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
RK K H H L++ ++F+C+ K F K S R+ R HTG + F
Sbjct: 45 RKGCKHVDECTGHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHF 104
Query: 1751 HCTLCE----------------------------KAFNQKSALQVHMKKHTGERPYKCAY 1782
C C KAFN S L H + HTGE+PYKC
Sbjct: 105 KCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEE 164
Query: 1783 CVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
C F Q S + H K H+ +E E+ G+ + HL
Sbjct: 165 CGKAFNQSSQLTRH-KIIHT-----EEKPNKCEECGKAFKQASHL 203
Score = 58.5 bits (140), Expect = 6e-08
Identities = 36/136 (26%), Positives = 54/136 (39%), Gaps = 4/136 (2%)
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
R + + +L+ KH + CT K + V T K ++C++ K F
Sbjct: 33 RYGKCEYENLQLRKGCKHVDECT----GHKGGHNTVNQCLTATPSKIFQCNKYVKVFDKF 88
Query: 1208 STLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRK 1267
S + + + HTG K F C CS +F L H R+HT +KC C F
Sbjct: 89 SNSNRYKRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFNWFSTLT 148
Query: 1268 THMQFHYKPDPKKARK 1283
H + H P K +
Sbjct: 149 KHKRIHTGEKPYKCEE 164
Score = 35.8 bits (81), Expect = 0.40
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + + ++C EC ++F+ + L H K +H E+ + C
Sbjct: 694 CEECG-KAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIH-KIIHTGEKPYKCG 751
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCD 1725
+AF +++L H + H + +KP +KC+
Sbjct: 752 DYGRAFNLSSNLTTHKKIH------TGEKP--YKCE 779
>gi|156547246 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 291 bits (744), Expect = 5e-78
Identities = 202/688 (29%), Positives = 277/688 (40%), Gaps = 128/688 (18%)
Query: 85 KCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHR 144
K G+ C C K F++ ++L +H +H E+ CSECG FT++S L +H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH- 307
Query: 145 QELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGK 204
G + + C C K F +S L H R I Y C CGK
Sbjct: 308 ---TGEKPYKCHECGKVFRHNSYLATH----------------RRIHTGEKPYKCNECGK 348
Query: 205 TFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQ 264
F+ S LT H IHTGE+PFKC+ECGK F Q L +H HTGEKP+ C C AFS
Sbjct: 349 AFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSV 408
Query: 265 KGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHV 324
+ +L H Q +H+ K Y C EC VF+ L H ++H G + A
Sbjct: 409 RSSLAIH-QTIHTGEK---PYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFS 463
Query: 325 LTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLS 383
+ + L Q ++P S V Q +L+ + +G+ P +
Sbjct: 464 MHSNL--------ATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 384 ITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAE 443
+ + +SG
Sbjct: 516 KAFSVRSSLTTHQAIHSG------------------------------------------ 533
Query: 444 QEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPY----CAKEFRKPSDLVR 499
E P K + K +K +R G+ PY C K F + S L R
Sbjct: 534 -----EKPYKCIECGKSFTQKSH------LRSHRGIHSGEKPYKCNECGKVFAQTSQLAR 582
Query: 500 HIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRL 559
H R+HT EKP+KC C RAF+ +S+LT H HTG K +KC C K F + L H R+
Sbjct: 583 HWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRI 642
Query: 560 HTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDI 618
HTG +P+ C C K F + TH H KP K + GK
Sbjct: 643 HTGEKPYKCNECGKAFSMHSNLTTHKVIHTGE----------KPYKCNQCGKV------- 685
Query: 619 PLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRS 678
+N N+ + ++PY+C C +A+ L H
Sbjct: 686 ----------------FTQNSHLA---NHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Query: 679 HTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDL 738
HTG+KP+KC++CG+ F L H R HTG K ++C C AF SL HM IH
Sbjct: 727 HTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE 786
Query: 739 RPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+ Y C C K F+ S N H + H E
Sbjct: 787 KRYKCNECGKVFRQSSNLASHHRMHTGE 814
Score = 266 bits (681), Expect = 1e-70
Identities = 182/665 (27%), Positives = 274/665 (41%), Gaps = 85/665 (12%)
Query: 132 LQSQLAVHMEEHRQEL----AGTRQHACKACKKEFETSSELK-----------EHMKTHY 176
+ +QL V H EL + + C +K S + K ++
Sbjct: 177 MNNQLGVSFHSHLPELQLFQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYH 236
Query: 177 KIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQ 236
++ S + R + G Y C CGK F + S LT H RIH+GE+P+KCSECGK F
Sbjct: 237 ELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTV 296
Query: 237 KGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKS 296
+ L H + HTGEKP+ C C F L +H +R+H+ K Y C EC F+
Sbjct: 297 RSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATH-RRIHTGEK---PYKCNECGKAFRG 352
Query: 297 LGSLNTHISKMHMGGPQNSTSS-----TETAHVLTATLFQTLPLQQTEAQATSASSQPSS 351
+L TH +H G + T+ +H+++ T + A S SS
Sbjct: 353 HSNLTTH-QLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSS 411
Query: 352 QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPA---- 407
A+ I +G+ P + N + + ++G
Sbjct: 412 LAIHQTI------------HTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECG 459
Query: 408 ---AAHPNDSCH--AKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMI 462
+ H N + H T + + S V + + + + E P K ++ K
Sbjct: 460 KAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFS 519
Query: 463 KKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVK 522
+ S +I +G + + C C K F + S L H IH+ EKP+KC +C + FA
Sbjct: 520 VRSSLTTHQAI--HSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQT 577
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S L H + HTG K +KC C ++FS SL H +HTG +P+ C C K FR + +
Sbjct: 578 SQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLA 637
Query: 583 THIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFF 641
TH R++ KP K GK
Sbjct: 638 TH----------RRIHTGEKPYKCNECGKA--------------------------FSMH 661
Query: 642 QSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+ + ++ ++PYKC C + + ++ HL H R+HTGEKP++C++CG+ F L
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H HTG K +KC C FT L H IH +PY C C K F+ + HM
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA 781
Query: 762 THRYE 766
H E
Sbjct: 782 IHTGE 786
Score = 255 bits (652), Expect = 2e-67
Identities = 188/672 (27%), Positives = 271/672 (40%), Gaps = 101/672 (15%)
Query: 43 LLSFPKESQFQRHMRDHERND--------------KPHRCDQCPQTFNVEFNLTLHKCTH 88
L P Q R + HE N KP++C++C + F NLT H+ H
Sbjct: 220 LQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIH 279
Query: 89 SGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQEL 147
SGE P C C K F+ ++L H ++H E+ C ECG F S LA H H
Sbjct: 280 SGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIH---- 335
Query: 148 AGTRQHACKACKKEFETSSELKEHMKTHY-----------KIRVSSTRSYNR-NIDRSGF 195
G + + C C K F S L H H K+ ++ + I
Sbjct: 336 TGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEK 395
Query: 196 TYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHAC 255
Y C CGK F S L H IHTGE+P+KC+ECGK F L H HTGEKP+ C
Sbjct: 396 PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKC 455
Query: 256 AFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNS 315
C AFS NL +H Q +H+ K + C ECS VF L H ++H G
Sbjct: 456 NECGKAFSMHSNLATH-QVIHTGTK---PFKCNECSKVFTQNSQLANH-RRIHTGEKPYK 510
Query: 316 TSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQ 374
+ A + ++L T QA + +P Q L + SG+
Sbjct: 511 CNECGKAFSVRSSL--------TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGE 562
Query: 375 SPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSN 434
P + + + ++G P+ N D +
Sbjct: 563 KPYKCNECGKVFAQTSQLARHWRVHTG------------------EKPYKCN-DCGRAFS 603
Query: 435 EQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKP 494
+++ T + E P K + K + + + +L R G + + C C K F
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGK--VFRHNSYLATHRRIHTGEKPYKCNECGKAFSMH 661
Query: 495 SDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLK 554
S+L H IHT EKP+KC QC + F S L H +THTG K ++C C K+FS SL
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 555 VHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP 614
H +HTG +P+ C C K F + H H ++ G
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANH-------------------RRIHTG----- 757
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQ 674
++P T+ G + S + ++ ++ YKC C + +++S +L
Sbjct: 758 ------EKPYRCTECGKAFRVR-----SSLTTHMAIHTGEKRYKCNECGKVFRQSSNLAS 806
Query: 675 HIRSHTGEKPFK 686
H R HTGEKP+K
Sbjct: 807 HHRMHTGEKPYK 818
Score = 250 bits (639), Expect = 8e-66
Identities = 169/579 (29%), Positives = 245/579 (42%), Gaps = 51/579 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F + S H R H +KP++C +C +TF V NLT+H+ H+GE P C
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHS-GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKC 315
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F S L H H G + C
Sbjct: 316 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH----TGEKPFKC 371
Query: 156 KACKKEFETSSELKEHMKTH-----YK-------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
C K F +S L H + H YK V S+ + ++ I Y C CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S L RH R+HTGE+P+KC+ECGKAF+ L TH + HTG KP C C F+
Sbjct: 432 KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFT 491
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGP-----QNSTSS 318
Q L +H +R+H+ K Y C EC F SL TH +H G + S
Sbjct: 492 QNSQLANH-RRIHTGEK---PYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSF 546
Query: 319 TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQP 378
T+ +H+ ++ S V Q +L+ V +G+ P
Sbjct: 547 TQKSHL------------RSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 379 GQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPH-----AQNP----DV 429
+ ++G H A H + P +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 430 SSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAK 489
+ ++ T + E P K ++ K + ++ L R G + + C C K
Sbjct: 655 GKAFSMHSNLTTHKVIHTGEKPYKCNQCGK--VFTQNSHLANHQRTHTGEKPYRCNECGK 712
Query: 490 EFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFST 549
F S L H IHT +KP+KC +C + F + L H + HTG K ++C C K+F
Sbjct: 713 AFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRV 772
Query: 550 SGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
SL H+ +HTG + + C C K FR S + +H H
Sbjct: 773 RSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 196 bits (497), Expect = 2e-49
Identities = 110/322 (34%), Positives = 149/322 (46%), Gaps = 10/322 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F+ +S+L +H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 423 KPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFK 482
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C+ FT N L H H KPYKC C + F + + HQ + S
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSV----RSSLTTHQAIHSGEKPYK 538
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE---ETAQLAKIRPQESATVSEKVLVQ 1141
E G ++ S R +P + +T+QLA+ + K
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
A DR S + ++P C C K F+ S L H RIHTGEKPYKC+ECG
Sbjct: 599 GRAFSDRSSLTFHQAIHTGEKPYK---CHECGKVFRHNSYLATHRRIHTGEKPYKCNECG 655
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F++ S L H HTG+K + C+ C F+ L H R HTG KP++C C F
Sbjct: 656 KAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFS 715
Query: 1262 TSGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 716 VRSSLTTHQAIHTGKKPYKCNE 737
Score = 192 bits (489), Expect = 2e-48
Identities = 103/321 (32%), Positives = 150/321 (46%), Gaps = 8/321 (2%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C K F ++SHL H R HTGEKPYKC CG+ F L H+ HTG K +
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C F N L RH H KPYKC C + F ++H ++ HQ + +
Sbjct: 427 CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF--SMH--SNLATHQVIHTGTKPFK 482
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL--VQS 1142
E + + + + R +P + + + + ++ EK ++
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIEC 542
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
+ S LR + E + C C K F + S L RH R+HTGEKPYKC++CG+
Sbjct: 543 GKSFTQKSHLRSHRGIHSGEKPYK--CNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGR 600
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+F+ +S+L H HTG+K + CH C F L H R+HTG KP+KC C F
Sbjct: 601 AFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSM 660
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 661 HSNLTTHKVIHTGEKPYKCNQ 681
Score = 186 bits (471), Expect = 2e-46
Identities = 110/317 (34%), Positives = 148/317 (46%), Gaps = 34/317 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F + SHL+ H H+GEKPYKC CG+ F + L H + HTG K +
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F+ SLT H A H KPYKC C + FR + H + H TG
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH---------TG 645
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E + C + HS+ + + T E+ + + KV Q+
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHK------VIHTGEKPYKCNQCG---------KVFTQN- 689
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
S L + Q E + C C K+F S L H IHTG+KPYKC+ECGK
Sbjct: 690 ------SHLANHQRTHTGEKPYR--CNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKV 741
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
FT + L H + HTG+K + C C AF + SL HM +HTG K +KC C FR S
Sbjct: 742 FTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQS 801
Query: 1264 GRRKTHMQFHYKPDPKK 1280
+H + H P K
Sbjct: 802 SNLASHHRMHTGEKPYK 818
Score = 185 bits (470), Expect = 3e-46
Identities = 113/347 (32%), Positives = 162/347 (46%), Gaps = 19/347 (5%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P K ++ K + S + +I G + + C C K FR S L RH R+HT EK
Sbjct: 394 EKPYKCNECGKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVHTGEK 451
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+KC +C +AF++ S L H HTG K FKC C K F+ + L H R+HTG +P+ C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 569 PHCDKKFRTSGHRKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEP 623
C K F TH A H +K E K Q+ + G + ++P
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSG-------EKP 564
Query: 624 ILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
+ G + + ++ V+ ++PYKC C RA+ L H HTGEK
Sbjct: 565 YKCNECGKV--FAQTSQLARHWR---VHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEK 619
Query: 684 PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMC 743
P+KC +CG+ F L H R HTG K +KC C AF+ +L H IH +PY C
Sbjct: 620 PYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 744 PYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSM 790
C K F + + H +TH E + + +A S+ S Q++
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Score = 184 bits (467), Expect = 7e-46
Identities = 101/306 (33%), Positives = 147/306 (48%), Gaps = 25/306 (8%)
Query: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYC 543
C C K F + S L+ H RIHT EKP+KC +C +AF+V+S+L H HTG K +KC C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH-----FKHTELRKMR 598
K F + L H R+HTG +P+ C C K F + TH H FK E K+
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 599 HQRKPA----KVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEAD 654
Q ++ G ++P + G + S + ++ +
Sbjct: 491 TQNSQLANHRRIHTG-----------EKPYKCNECGKAFSVRS-----SLTTHQAIHSGE 534
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+PYKC C +++ + HL+ H H+GEKP+KC++CG+ F L H R HTG K +K
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
C C AF+ SL H IH +PY C C K F+ + H + H E + +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 775 QQAASI 780
+A S+
Sbjct: 655 GKAFSM 660
Score = 183 bits (465), Expect = 1e-45
Identities = 107/324 (33%), Positives = 145/324 (44%), Gaps = 34/324 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C+K F ++S L H R HTGEKPYKC CG+ F L +H+ H+G K +
Sbjct: 479 KPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK 538
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C SFT L H H KPYKC C + F T +H + H TG
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVH---------TG 589
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E C + SDR++ +TF + + E V +
Sbjct: 590 EKPYK--CNDCGRAFSDRSS--------LTFHQAIHTGEKPYKCHECGKVFRHNSYLATH 639
Query: 1145 EKDRISELRDKQAELQDE-PKHANC--------------CTYCPKSFKKPSDLVRHVRIH 1189
+ E K E H+N C C K F + S L H R H
Sbjct: 640 RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTH 699
Query: 1190 TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
TGEKPY+C+ECGK+F+V+S+L H HTG+K + C+ C F+ L H R+HTG K
Sbjct: 700 TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK 759
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
P++C C FR THM H
Sbjct: 760 PYRCTECGKAFRVRSSLTTHMAIH 783
Score = 183 bits (464), Expect = 2e-45
Identities = 114/345 (33%), Positives = 152/345 (44%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F+ +S+L H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 311 KPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFK 370
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGF--------RTTVH----------C 1066
C+ C FT N L H H KPYKC C + F T+H C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 1067 KK------HMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEET 1120
K ++ RH+ V + E G + + ++P +
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 1121 AQLAKIRPQESATVSEKVLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
Q +++ EK + K S L QA E + C C KSF +
Sbjct: 491 TQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK--CIECGKSFTQ 548
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S L H IH+GEKPYKC+ECGK F S L H + HTG+K + C+ C AFS + SL
Sbjct: 549 KSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSL 608
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HTG KP+KC C FR + TH + H P K +
Sbjct: 609 TFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNE 653
Score = 181 bits (458), Expect = 8e-45
Identities = 99/275 (36%), Positives = 136/275 (49%), Gaps = 27/275 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F + SQ RH R H +KP++C+ C + F+ +LT H+ H+GE P C
Sbjct: 565 YKCNECGKVFAQTSQLARHWRVHT-GEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKC 623
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F++ S L H H G + + C
Sbjct: 624 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH----TGEKPYKC 679
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F +S L H +TH + Y C CGK F S LT H
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEK----------------PYRCNECGKAFSVRSSLTTH 723
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
IHTG++P+KC+ECGK F Q L H HTGEKP+ C C AF + +L +H+ +
Sbjct: 724 QAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA-I 782
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C EC VF+ +L +H +MH G
Sbjct: 783 HTGEKR---YKCNECGKVFRQSSNLASH-HRMHTG 813
Score = 180 bits (456), Expect = 1e-44
Identities = 103/316 (32%), Positives = 141/316 (44%), Gaps = 32/316 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F ++S+L H R H+GEKPYKC CG+ F L H+ HTG K +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C F N L H H KPYKC C + FR ++ HQ + +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRG----HSNLTTHQLIHTGEKPFK 370
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G + + +I+ T + +P + + V+S+
Sbjct: 371 CNECGKLFTQNS--------------HLISHWRIHTGE----KPYKCNECGKAFSVRSSL 412
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ +K + C C K F+ S L RH R+HTGEKPYKC+ECGK+F
Sbjct: 413 AIHQTIHTGEKPYK----------CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF 462
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
++ S L H HTG K F C+ CS F+ L H R+HTG KP+KC C F
Sbjct: 463 SMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRS 522
Query: 1265 RRKTHMQFHYKPDPKK 1280
TH H P K
Sbjct: 523 SLTTHQAIHSGEKPYK 538
Score = 149 bits (375), Expect = 3e-35
Identities = 78/218 (35%), Positives = 109/218 (50%), Gaps = 22/218 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F S H R H +KP++C++C + F++ NLT HK H+GE P C
Sbjct: 621 YKCHECGKVFRHNSYLATHRRIHT-GEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F++ + L H H E+ C+ECG F+++S L H H G + + C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIH----TGKKPYKC 735
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F ++ L H + H + Y C CGK F+ S LT H
Sbjct: 736 NECGKVFTQNAHLANHRRIHTGEK----------------PYRCTECGKAFRVRSSLTTH 779
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPH 253
+ IHTGE+ +KC+ECGK F Q L +H HTGEKP+
Sbjct: 780 MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817
Score = 127 bits (319), Expect = 1e-28
Identities = 75/273 (27%), Positives = 120/273 (43%), Gaps = 35/273 (12%)
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S LT K ++ K +KC C K+F+ + +L H R+H+G +P+ C C K F +
Sbjct: 242 SLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLT 301
Query: 583 THIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ 642
H H ++P + G + N +
Sbjct: 302 IHQVIHTG------------------------------EKPYKCHECGKV--FRHNSYLA 329
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
++ ++ ++PYKC C +A++ +L H HTGEKPFKC++CG+ F L +
Sbjct: 330 THRR---IHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLIS 386
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H R HTG K +KC C AF+ SL H IH +PY C C K F+ + +H +
Sbjct: 387 HWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRV 446
Query: 763 HRYELAQQLQQHQQAASIDDSTVDQQSMQASTQ 795
H E + + +A S+ + Q + T+
Sbjct: 447 HTGEKPYKCNECGKAFSMHSNLATHQVIHTGTK 479
Score = 118 bits (296), Expect = 5e-26
Identities = 53/115 (46%), Positives = 64/115 (55%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S+L H RIH+GEKPYKC ECGK+FTV+S L H HTG+K + CH C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHEC 318
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
F L H R+HTG KP+KC C FR TH H P K +
Sbjct: 319 GKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Score = 117 bits (294), Expect = 8e-26
Identities = 59/148 (39%), Positives = 87/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L H + +H E+ + C C K+F + +HL+ H H
Sbjct: 507 KPYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSFTQKSHLRSHRGIH------ 559
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C K FA+ SQL RH R+HTGE+P+ C C +AF+ +S+L H HTG
Sbjct: 560 SGEKP--YKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTG 617
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 618 EKPYKCHECGKVFRHNSYLATH-RRIHT 644
Score = 116 bits (291), Expect = 2e-25
Identities = 58/142 (40%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + VH E+ + C C KAF ++L H H
Sbjct: 423 KPYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIH------ 475
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP FKC+ C K F + SQL H RIHTGE+P+ C C KAF+ +S+L H H+G
Sbjct: 476 TGTKP--FKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSG 533
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C FTQKS+++ H
Sbjct: 534 EKPYKCIECGKSFTQKSHLRSH 555
Score = 111 bits (278), Expect = 6e-24
Identities = 59/162 (36%), Positives = 84/162 (51%), Gaps = 21/162 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++C EC +AFS + L H K +H E+ + C C K F + +HL H +TH
Sbjct: 647 KPYKCNECGKAFSMHSNLTTH-KVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPY 705
Query: 1709 ---QAGPSLSSQKP-----------RVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
+ G + S + + +KC+ C K F + + L H RIHTGE+P+ CT
Sbjct: 706 RCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTE 765
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
C KAF +S+L HM HTGE+ YKC C F Q SN+ H
Sbjct: 766 CGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASH 807
Score = 108 bits (270), Expect = 5e-23
Identities = 51/142 (35%), Positives = 78/142 (54%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C+EC ++F+ + L H + +H E+ + C C K F + + L H + H
Sbjct: 535 KPYKCIECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVH------ 587
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C +AF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 588 TGEKP--YKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTG 645
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTH 667
Score = 107 bits (267), Expect = 1e-22
Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF ++L H H
Sbjct: 619 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH------ 671
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F + S L H R HTGE+P+ C C KAF+ +S+L H HTG
Sbjct: 672 TGEKP--YKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIHTG 729
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
++PYKC C FTQ +++ H +R H+
Sbjct: 730 KKPYKCNECGKVFTQNAHLANH-RRIHT 756
Score = 106 bits (265), Expect = 2e-22
Identities = 55/156 (35%), Positives = 83/156 (53%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ NL + + ++C EC + F+ + L H + +H E+ + C C K F+ ++
Sbjct: 269 NSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIH-QVIHTGEKPYKCHECGKVFRHNSY 327
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C KAF S L H IHTGE+PF C C K F
Sbjct: 328 LATHRRIH------TGEKP--YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFT 379
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
Q S L H + HTGE+PYKC C F+ +S++ +H
Sbjct: 380 QNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH 415
Score = 106 bits (265), Expect = 2e-22
Identities = 56/148 (37%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF+ ++L H H
Sbjct: 311 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH------ 363
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP FKC+ C K F + S L H RIHTGE+P+ C C KAF+ +S+L +H HTG
Sbjct: 364 TGEKP--FKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTG 421
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 422 EKPYKCNECGKVFRYNSYLGRH-RRVHT 448
Score = 104 bits (259), Expect = 9e-22
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C+ C K+F S+L H IHTGEKPYKC ECGK F S L H + HTG+K + C+ C
Sbjct: 287 CSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 346
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AF +L H +HTG KPFKC C F + +H + H P K +
Sbjct: 347 GKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNE 401
Score = 104 bits (259), Expect = 9e-22
Identities = 54/142 (38%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L H +H E+ C C K F + +HL H + H
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQL-IHTGEKPFKCNECGKLFTQNSHLISHWRIH------ 391
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 392 TGEKP--YKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTG 449
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 450 EKPYKCNECGKAFSMHSNLATH 471
Score = 103 bits (256), Expect = 2e-21
Identities = 50/149 (33%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Query: 932 NVTTRLIQESSQEELDLQAQGSQFLEDNE-------DQSRRSYRCDYCNKGFKKSSHLKQ 984
N+TT + + ++ G F +++ + YRC+ C K F S L
Sbjct: 663 NLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 985 HVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMAT 1044
H HTG+KPYKC CG+ F + L +H + HTG K + C+ C +F SLT HMA
Sbjct: 723 HQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI 782
Query: 1045 HMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
H K YKC C + FR + + H + H
Sbjct: 783 HTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 102 bits (254), Expect = 3e-21
Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC + F+ + L+ H + +H E+ + C C KAF + L H H + +
Sbjct: 370 KCNECGKLFTQNSHLISHWR-IHTGEKPYKCNECGKAFSVRSSLAIHQTIH------TGE 422
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP +KC+ C K F S L RH R+HTGE+P+ C C KAF+ S L H HTG +P
Sbjct: 423 KP--YKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP 480
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
+KC C FTQ S + H +R H+
Sbjct: 481 FKCNECSKVFTQNSQLANH-RRIHT 504
Score = 92.0 bits (227), Expect = 5e-18
Identities = 49/139 (35%), Positives = 72/139 (51%), Gaps = 9/139 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ +LA + + ++C EC +AFS + L H + +H ++ + C C K F + H
Sbjct: 689 NSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH-QAIHTGKKPYKCNECGKVFTQNAH 747
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP ++C C KAF S L H IHTGE+ + C C K F
Sbjct: 748 LANHRRIH------TGEKP--YRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFR 799
Query: 1761 QKSALQVHMKKHTGERPYK 1779
Q S L H + HTGE+PYK
Sbjct: 800 QSSNLASHHRMHTGEKPYK 818
Score = 89.0 bits (219), Expect = 4e-17
Identities = 37/91 (40%), Positives = 52/91 (57%)
Query: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK 1252
KPYKC+ECGK+FT S L H + H+G+K + C C F+ + +L +H +HTG KP+K
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1253 CPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C C FR + TH + H P K +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNE 345
Score = 85.9 bits (211), Expect = 3e-16
Identities = 36/89 (40%), Positives = 50/89 (56%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K F +++HL H R HTGEKPY+C CG+ F L +H HTG K +
Sbjct: 730 KKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRY 789
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYK 1052
C+ C F + +L H H KPYK
Sbjct: 790 KCNECGKVFRQSSNLASHHRMHTGEKPYK 818
Score = 81.6 bits (200), Expect = 6e-15
Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
EG+ ++C + +++ ++ + + +++ + H K + H Q +A
Sbjct: 198 EGKMYECNQVEKSTNNGSSVSP-LQQIPSSVQTHRS----KKYHELNHFSLLTQRRKAN- 251
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
S KP +KC+ C KAF + S L H RIH+GE+P+ C+ C K F +S L +H H
Sbjct: 252 --SCGKP--YKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH 307
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
TGE+PYKC C F S + H +R H+
Sbjct: 308 TGEKPYKCHECGKVFRHNSYLATH-RRIHT 336
Score = 48.9 bits (115), Expect = 5e-05
Identities = 21/69 (30%), Positives = 31/69 (44%)
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
K ++ K + C+ C AF+ +L H R+H+G KP+KC C F H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308
Query: 1275 KPDPKKARK 1283
P K +
Sbjct: 309 GEKPYKCHE 317
>gi|38788302 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 291 bits (744), Expect = 5e-78
Identities = 202/688 (29%), Positives = 277/688 (40%), Gaps = 128/688 (18%)
Query: 85 KCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHR 144
K G+ C C K F++ ++L +H +H E+ CSECG FT++S L +H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH- 307
Query: 145 QELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGK 204
G + + C C K F +S L H R I Y C CGK
Sbjct: 308 ---TGEKPYKCHECGKVFRHNSYLATH----------------RRIHTGEKPYKCNECGK 348
Query: 205 TFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQ 264
F+ S LT H IHTGE+PFKC+ECGK F Q L +H HTGEKP+ C C AFS
Sbjct: 349 AFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSV 408
Query: 265 KGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHV 324
+ +L H Q +H+ K Y C EC VF+ L H ++H G + A
Sbjct: 409 RSSLAIH-QTIHTGEK---PYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFS 463
Query: 325 LTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLS 383
+ + L Q ++P S V Q +L+ + +G+ P +
Sbjct: 464 MHSNL--------ATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 384 ITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAE 443
+ + +SG
Sbjct: 516 KAFSVRSSLTTHQAIHSG------------------------------------------ 533
Query: 444 QEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPY----CAKEFRKPSDLVR 499
E P K + K +K +R G+ PY C K F + S L R
Sbjct: 534 -----EKPYKCIECGKSFTQKSH------LRSHRGIHSGEKPYKCNECGKVFAQTSQLAR 582
Query: 500 HIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRL 559
H R+HT EKP+KC C RAF+ +S+LT H HTG K +KC C K F + L H R+
Sbjct: 583 HWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRI 642
Query: 560 HTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDI 618
HTG +P+ C C K F + TH H KP K + GK
Sbjct: 643 HTGEKPYKCNECGKAFSMHSNLTTHKVIHTGE----------KPYKCNQCGKV------- 685
Query: 619 PLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRS 678
+N N+ + ++PY+C C +A+ L H
Sbjct: 686 ----------------FTQNSHLA---NHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Query: 679 HTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDL 738
HTG+KP+KC++CG+ F L H R HTG K ++C C AF SL HM IH
Sbjct: 727 HTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE 786
Query: 739 RPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+ Y C C K F+ S N H + H E
Sbjct: 787 KRYKCNECGKVFRQSSNLASHHRMHTGE 814
Score = 266 bits (681), Expect = 1e-70
Identities = 182/665 (27%), Positives = 274/665 (41%), Gaps = 85/665 (12%)
Query: 132 LQSQLAVHMEEHRQEL----AGTRQHACKACKKEFETSSELK-----------EHMKTHY 176
+ +QL V H EL + + C +K S + K ++
Sbjct: 177 MNNQLGVSFHSHLPELQLFQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYH 236
Query: 177 KIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQ 236
++ S + R + G Y C CGK F + S LT H RIH+GE+P+KCSECGK F
Sbjct: 237 ELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTV 296
Query: 237 KGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKS 296
+ L H + HTGEKP+ C C F L +H +R+H+ K Y C EC F+
Sbjct: 297 RSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATH-RRIHTGEK---PYKCNECGKAFRG 352
Query: 297 LGSLNTHISKMHMGGPQNSTSS-----TETAHVLTATLFQTLPLQQTEAQATSASSQPSS 351
+L TH +H G + T+ +H+++ T + A S SS
Sbjct: 353 HSNLTTH-QLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSS 411
Query: 352 QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPA---- 407
A+ I +G+ P + N + + ++G
Sbjct: 412 LAIHQTI------------HTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECG 459
Query: 408 ---AAHPNDSCH--AKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMI 462
+ H N + H T + + S V + + + + E P K ++ K
Sbjct: 460 KAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFS 519
Query: 463 KKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVK 522
+ S +I +G + + C C K F + S L H IH+ EKP+KC +C + FA
Sbjct: 520 VRSSLTTHQAI--HSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQT 577
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S L H + HTG K +KC C ++FS SL H +HTG +P+ C C K FR + +
Sbjct: 578 SQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLA 637
Query: 583 THIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFF 641
TH R++ KP K GK
Sbjct: 638 TH----------RRIHTGEKPYKCNECGKA--------------------------FSMH 661
Query: 642 QSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+ + ++ ++PYKC C + + ++ HL H R+HTGEKP++C++CG+ F L
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H HTG K +KC C FT L H IH +PY C C K F+ + HM
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA 781
Query: 762 THRYE 766
H E
Sbjct: 782 IHTGE 786
Score = 255 bits (652), Expect = 2e-67
Identities = 188/672 (27%), Positives = 271/672 (40%), Gaps = 101/672 (15%)
Query: 43 LLSFPKESQFQRHMRDHERND--------------KPHRCDQCPQTFNVEFNLTLHKCTH 88
L P Q R + HE N KP++C++C + F NLT H+ H
Sbjct: 220 LQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIH 279
Query: 89 SGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQEL 147
SGE P C C K F+ ++L H ++H E+ C ECG F S LA H H
Sbjct: 280 SGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIH---- 335
Query: 148 AGTRQHACKACKKEFETSSELKEHMKTHY-----------KIRVSSTRSYNR-NIDRSGF 195
G + + C C K F S L H H K+ ++ + I
Sbjct: 336 TGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEK 395
Query: 196 TYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHAC 255
Y C CGK F S L H IHTGE+P+KC+ECGK F L H HTGEKP+ C
Sbjct: 396 PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKC 455
Query: 256 AFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNS 315
C AFS NL +H Q +H+ K + C ECS VF L H ++H G
Sbjct: 456 NECGKAFSMHSNLATH-QVIHTGTK---PFKCNECSKVFTQNSQLANH-RRIHTGEKPYK 510
Query: 316 TSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQ 374
+ A + ++L T QA + +P Q L + SG+
Sbjct: 511 CNECGKAFSVRSSL--------TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGE 562
Query: 375 SPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSN 434
P + + + ++G P+ N D +
Sbjct: 563 KPYKCNECGKVFAQTSQLARHWRVHTG------------------EKPYKCN-DCGRAFS 603
Query: 435 EQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKP 494
+++ T + E P K + K + + + +L R G + + C C K F
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGK--VFRHNSYLATHRRIHTGEKPYKCNECGKAFSMH 661
Query: 495 SDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLK 554
S+L H IHT EKP+KC QC + F S L H +THTG K ++C C K+FS SL
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 555 VHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP 614
H +HTG +P+ C C K F + H H ++ G
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANH-------------------RRIHTG----- 757
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQ 674
++P T+ G + S + ++ ++ YKC C + +++S +L
Sbjct: 758 ------EKPYRCTECGKAFRVR-----SSLTTHMAIHTGEKRYKCNECGKVFRQSSNLAS 806
Query: 675 HIRSHTGEKPFK 686
H R HTGEKP+K
Sbjct: 807 HHRMHTGEKPYK 818
Score = 250 bits (639), Expect = 8e-66
Identities = 169/579 (29%), Positives = 245/579 (42%), Gaps = 51/579 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F + S H R H +KP++C +C +TF V NLT+H+ H+GE P C
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHS-GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKC 315
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F S L H H G + C
Sbjct: 316 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH----TGEKPFKC 371
Query: 156 KACKKEFETSSELKEHMKTH-----YK-------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
C K F +S L H + H YK V S+ + ++ I Y C CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S L RH R+HTGE+P+KC+ECGKAF+ L TH + HTG KP C C F+
Sbjct: 432 KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFT 491
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGP-----QNSTSS 318
Q L +H +R+H+ K Y C EC F SL TH +H G + S
Sbjct: 492 QNSQLANH-RRIHTGEK---PYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSF 546
Query: 319 TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQP 378
T+ +H+ ++ S V Q +L+ V +G+ P
Sbjct: 547 TQKSHL------------RSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 379 GQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPH-----AQNP----DV 429
+ ++G H A H + P +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 430 SSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAK 489
+ ++ T + E P K ++ K + ++ L R G + + C C K
Sbjct: 655 GKAFSMHSNLTTHKVIHTGEKPYKCNQCGK--VFTQNSHLANHQRTHTGEKPYRCNECGK 712
Query: 490 EFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFST 549
F S L H IHT +KP+KC +C + F + L H + HTG K ++C C K+F
Sbjct: 713 AFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRV 772
Query: 550 SGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
SL H+ +HTG + + C C K FR S + +H H
Sbjct: 773 RSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 196 bits (497), Expect = 2e-49
Identities = 110/322 (34%), Positives = 149/322 (46%), Gaps = 10/322 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F+ +S+L +H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 423 KPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFK 482
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C+ FT N L H H KPYKC C + F + + HQ + S
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSV----RSSLTTHQAIHSGEKPYK 538
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE---ETAQLAKIRPQESATVSEKVLVQ 1141
E G ++ S R +P + +T+QLA+ + K
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
A DR S + ++P C C K F+ S L H RIHTGEKPYKC+ECG
Sbjct: 599 GRAFSDRSSLTFHQAIHTGEKPYK---CHECGKVFRHNSYLATHRRIHTGEKPYKCNECG 655
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F++ S L H HTG+K + C+ C F+ L H R HTG KP++C C F
Sbjct: 656 KAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFS 715
Query: 1262 TSGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 716 VRSSLTTHQAIHTGKKPYKCNE 737
Score = 192 bits (489), Expect = 2e-48
Identities = 103/321 (32%), Positives = 150/321 (46%), Gaps = 8/321 (2%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C K F ++SHL H R HTGEKPYKC CG+ F L H+ HTG K +
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C F N L RH H KPYKC C + F ++H ++ HQ + +
Sbjct: 427 CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF--SMH--SNLATHQVIHTGTKPFK 482
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL--VQS 1142
E + + + + R +P + + + + ++ EK ++
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIEC 542
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
+ S LR + E + C C K F + S L RH R+HTGEKPYKC++CG+
Sbjct: 543 GKSFTQKSHLRSHRGIHSGEKPYK--CNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGR 600
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+F+ +S+L H HTG+K + CH C F L H R+HTG KP+KC C F
Sbjct: 601 AFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSM 660
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 661 HSNLTTHKVIHTGEKPYKCNQ 681
Score = 186 bits (471), Expect = 2e-46
Identities = 110/317 (34%), Positives = 148/317 (46%), Gaps = 34/317 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F + SHL+ H H+GEKPYKC CG+ F + L H + HTG K +
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F+ SLT H A H KPYKC C + FR + H + H TG
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH---------TG 645
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E + C + HS+ + + T E+ + + KV Q+
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHK------VIHTGEKPYKCNQCG---------KVFTQN- 689
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
S L + Q E + C C K+F S L H IHTG+KPYKC+ECGK
Sbjct: 690 ------SHLANHQRTHTGEKPYR--CNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKV 741
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
FT + L H + HTG+K + C C AF + SL HM +HTG K +KC C FR S
Sbjct: 742 FTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQS 801
Query: 1264 GRRKTHMQFHYKPDPKK 1280
+H + H P K
Sbjct: 802 SNLASHHRMHTGEKPYK 818
Score = 185 bits (470), Expect = 3e-46
Identities = 113/347 (32%), Positives = 162/347 (46%), Gaps = 19/347 (5%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P K ++ K + S + +I G + + C C K FR S L RH R+HT EK
Sbjct: 394 EKPYKCNECGKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVHTGEK 451
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+KC +C +AF++ S L H HTG K FKC C K F+ + L H R+HTG +P+ C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 569 PHCDKKFRTSGHRKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEP 623
C K F TH A H +K E K Q+ + G + ++P
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSG-------EKP 564
Query: 624 ILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
+ G + + ++ V+ ++PYKC C RA+ L H HTGEK
Sbjct: 565 YKCNECGKV--FAQTSQLARHWR---VHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEK 619
Query: 684 PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMC 743
P+KC +CG+ F L H R HTG K +KC C AF+ +L H IH +PY C
Sbjct: 620 PYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 744 PYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSM 790
C K F + + H +TH E + + +A S+ S Q++
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Score = 184 bits (467), Expect = 7e-46
Identities = 101/306 (33%), Positives = 147/306 (48%), Gaps = 25/306 (8%)
Query: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYC 543
C C K F + S L+ H RIHT EKP+KC +C +AF+V+S+L H HTG K +KC C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH-----FKHTELRKMR 598
K F + L H R+HTG +P+ C C K F + TH H FK E K+
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 599 HQRKPA----KVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEAD 654
Q ++ G ++P + G + S + ++ +
Sbjct: 491 TQNSQLANHRRIHTG-----------EKPYKCNECGKAFSVRS-----SLTTHQAIHSGE 534
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+PYKC C +++ + HL+ H H+GEKP+KC++CG+ F L H R HTG K +K
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
C C AF+ SL H IH +PY C C K F+ + H + H E + +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 775 QQAASI 780
+A S+
Sbjct: 655 GKAFSM 660
Score = 183 bits (465), Expect = 1e-45
Identities = 107/324 (33%), Positives = 145/324 (44%), Gaps = 34/324 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C+K F ++S L H R HTGEKPYKC CG+ F L +H+ H+G K +
Sbjct: 479 KPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK 538
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C SFT L H H KPYKC C + F T +H + H TG
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVH---------TG 589
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E C + SDR++ +TF + + E V +
Sbjct: 590 EKPYK--CNDCGRAFSDRSS--------LTFHQAIHTGEKPYKCHECGKVFRHNSYLATH 639
Query: 1145 EKDRISELRDKQAELQDE-PKHANC--------------CTYCPKSFKKPSDLVRHVRIH 1189
+ E K E H+N C C K F + S L H R H
Sbjct: 640 RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTH 699
Query: 1190 TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
TGEKPY+C+ECGK+F+V+S+L H HTG+K + C+ C F+ L H R+HTG K
Sbjct: 700 TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK 759
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
P++C C FR THM H
Sbjct: 760 PYRCTECGKAFRVRSSLTTHMAIH 783
Score = 183 bits (464), Expect = 2e-45
Identities = 114/345 (33%), Positives = 152/345 (44%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F+ +S+L H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 311 KPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFK 370
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGF--------RTTVH----------C 1066
C+ C FT N L H H KPYKC C + F T+H C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 1067 KK------HMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEET 1120
K ++ RH+ V + E G + + ++P +
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 1121 AQLAKIRPQESATVSEKVLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
Q +++ EK + K S L QA E + C C KSF +
Sbjct: 491 TQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK--CIECGKSFTQ 548
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S L H IH+GEKPYKC+ECGK F S L H + HTG+K + C+ C AFS + SL
Sbjct: 549 KSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSL 608
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HTG KP+KC C FR + TH + H P K +
Sbjct: 609 TFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNE 653
Score = 181 bits (458), Expect = 8e-45
Identities = 99/275 (36%), Positives = 136/275 (49%), Gaps = 27/275 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F + SQ RH R H +KP++C+ C + F+ +LT H+ H+GE P C
Sbjct: 565 YKCNECGKVFAQTSQLARHWRVHT-GEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKC 623
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F++ S L H H G + + C
Sbjct: 624 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH----TGEKPYKC 679
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F +S L H +TH + Y C CGK F S LT H
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEK----------------PYRCNECGKAFSVRSSLTTH 723
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
IHTG++P+KC+ECGK F Q L H HTGEKP+ C C AF + +L +H+ +
Sbjct: 724 QAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA-I 782
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C EC VF+ +L +H +MH G
Sbjct: 783 HTGEKR---YKCNECGKVFRQSSNLASH-HRMHTG 813
Score = 180 bits (456), Expect = 1e-44
Identities = 103/316 (32%), Positives = 141/316 (44%), Gaps = 32/316 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F ++S+L H R H+GEKPYKC CG+ F L H+ HTG K +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C F N L H H KPYKC C + FR ++ HQ + +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRG----HSNLTTHQLIHTGEKPFK 370
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G + + +I+ T + +P + + V+S+
Sbjct: 371 CNECGKLFTQNS--------------HLISHWRIHTGE----KPYKCNECGKAFSVRSSL 412
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ +K + C C K F+ S L RH R+HTGEKPYKC+ECGK+F
Sbjct: 413 AIHQTIHTGEKPYK----------CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF 462
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
++ S L H HTG K F C+ CS F+ L H R+HTG KP+KC C F
Sbjct: 463 SMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRS 522
Query: 1265 RRKTHMQFHYKPDPKK 1280
TH H P K
Sbjct: 523 SLTTHQAIHSGEKPYK 538
Score = 149 bits (375), Expect = 3e-35
Identities = 78/218 (35%), Positives = 109/218 (50%), Gaps = 22/218 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F S H R H +KP++C++C + F++ NLT HK H+GE P C
Sbjct: 621 YKCHECGKVFRHNSYLATHRRIHT-GEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F++ + L H H E+ C+ECG F+++S L H H G + + C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIH----TGKKPYKC 735
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F ++ L H + H + Y C CGK F+ S LT H
Sbjct: 736 NECGKVFTQNAHLANHRRIHTGEK----------------PYRCTECGKAFRVRSSLTTH 779
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPH 253
+ IHTGE+ +KC+ECGK F Q L +H HTGEKP+
Sbjct: 780 MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817
Score = 127 bits (319), Expect = 1e-28
Identities = 75/273 (27%), Positives = 120/273 (43%), Gaps = 35/273 (12%)
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S LT K ++ K +KC C K+F+ + +L H R+H+G +P+ C C K F +
Sbjct: 242 SLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLT 301
Query: 583 THIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ 642
H H ++P + G + N +
Sbjct: 302 IHQVIHTG------------------------------EKPYKCHECGKV--FRHNSYLA 329
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
++ ++ ++PYKC C +A++ +L H HTGEKPFKC++CG+ F L +
Sbjct: 330 THRR---IHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLIS 386
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H R HTG K +KC C AF+ SL H IH +PY C C K F+ + +H +
Sbjct: 387 HWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRV 446
Query: 763 HRYELAQQLQQHQQAASIDDSTVDQQSMQASTQ 795
H E + + +A S+ + Q + T+
Sbjct: 447 HTGEKPYKCNECGKAFSMHSNLATHQVIHTGTK 479
Score = 118 bits (296), Expect = 5e-26
Identities = 53/115 (46%), Positives = 64/115 (55%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S+L H RIH+GEKPYKC ECGK+FTV+S L H HTG+K + CH C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHEC 318
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
F L H R+HTG KP+KC C FR TH H P K +
Sbjct: 319 GKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Score = 117 bits (294), Expect = 8e-26
Identities = 59/148 (39%), Positives = 87/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L H + +H E+ + C C K+F + +HL+ H H
Sbjct: 507 KPYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSFTQKSHLRSHRGIH------ 559
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C K FA+ SQL RH R+HTGE+P+ C C +AF+ +S+L H HTG
Sbjct: 560 SGEKP--YKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTG 617
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 618 EKPYKCHECGKVFRHNSYLATH-RRIHT 644
Score = 116 bits (291), Expect = 2e-25
Identities = 58/142 (40%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + VH E+ + C C KAF ++L H H
Sbjct: 423 KPYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIH------ 475
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP FKC+ C K F + SQL H RIHTGE+P+ C C KAF+ +S+L H H+G
Sbjct: 476 TGTKP--FKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSG 533
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C FTQKS+++ H
Sbjct: 534 EKPYKCIECGKSFTQKSHLRSH 555
Score = 111 bits (278), Expect = 6e-24
Identities = 59/162 (36%), Positives = 84/162 (51%), Gaps = 21/162 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++C EC +AFS + L H K +H E+ + C C K F + +HL H +TH
Sbjct: 647 KPYKCNECGKAFSMHSNLTTH-KVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPY 705
Query: 1709 ---QAGPSLSSQKP-----------RVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
+ G + S + + +KC+ C K F + + L H RIHTGE+P+ CT
Sbjct: 706 RCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTE 765
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
C KAF +S+L HM HTGE+ YKC C F Q SN+ H
Sbjct: 766 CGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASH 807
Score = 108 bits (270), Expect = 5e-23
Identities = 51/142 (35%), Positives = 78/142 (54%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C+EC ++F+ + L H + +H E+ + C C K F + + L H + H
Sbjct: 535 KPYKCIECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVH------ 587
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C +AF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 588 TGEKP--YKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTG 645
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTH 667
Score = 107 bits (267), Expect = 1e-22
Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF ++L H H
Sbjct: 619 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH------ 671
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F + S L H R HTGE+P+ C C KAF+ +S+L H HTG
Sbjct: 672 TGEKP--YKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIHTG 729
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
++PYKC C FTQ +++ H +R H+
Sbjct: 730 KKPYKCNECGKVFTQNAHLANH-RRIHT 756
Score = 106 bits (265), Expect = 2e-22
Identities = 55/156 (35%), Positives = 83/156 (53%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ NL + + ++C EC + F+ + L H + +H E+ + C C K F+ ++
Sbjct: 269 NSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIH-QVIHTGEKPYKCHECGKVFRHNSY 327
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C KAF S L H IHTGE+PF C C K F
Sbjct: 328 LATHRRIH------TGEKP--YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFT 379
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
Q S L H + HTGE+PYKC C F+ +S++ +H
Sbjct: 380 QNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH 415
Score = 106 bits (265), Expect = 2e-22
Identities = 56/148 (37%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF+ ++L H H
Sbjct: 311 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH------ 363
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP FKC+ C K F + S L H RIHTGE+P+ C C KAF+ +S+L +H HTG
Sbjct: 364 TGEKP--FKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTG 421
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 422 EKPYKCNECGKVFRYNSYLGRH-RRVHT 448
Score = 104 bits (259), Expect = 9e-22
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C+ C K+F S+L H IHTGEKPYKC ECGK F S L H + HTG+K + C+ C
Sbjct: 287 CSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 346
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AF +L H +HTG KPFKC C F + +H + H P K +
Sbjct: 347 GKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNE 401
Score = 104 bits (259), Expect = 9e-22
Identities = 54/142 (38%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L H +H E+ C C K F + +HL H + H
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQL-IHTGEKPFKCNECGKLFTQNSHLISHWRIH------ 391
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 392 TGEKP--YKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTG 449
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 450 EKPYKCNECGKAFSMHSNLATH 471
Score = 103 bits (256), Expect = 2e-21
Identities = 50/149 (33%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Query: 932 NVTTRLIQESSQEELDLQAQGSQFLEDNE-------DQSRRSYRCDYCNKGFKKSSHLKQ 984
N+TT + + ++ G F +++ + YRC+ C K F S L
Sbjct: 663 NLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 985 HVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMAT 1044
H HTG+KPYKC CG+ F + L +H + HTG K + C+ C +F SLT HMA
Sbjct: 723 HQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI 782
Query: 1045 HMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
H K YKC C + FR + + H + H
Sbjct: 783 HTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 102 bits (254), Expect = 3e-21
Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC + F+ + L+ H + +H E+ + C C KAF + L H H + +
Sbjct: 370 KCNECGKLFTQNSHLISHWR-IHTGEKPYKCNECGKAFSVRSSLAIHQTIH------TGE 422
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP +KC+ C K F S L RH R+HTGE+P+ C C KAF+ S L H HTG +P
Sbjct: 423 KP--YKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP 480
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
+KC C FTQ S + H +R H+
Sbjct: 481 FKCNECSKVFTQNSQLANH-RRIHT 504
Score = 92.0 bits (227), Expect = 5e-18
Identities = 49/139 (35%), Positives = 72/139 (51%), Gaps = 9/139 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ +LA + + ++C EC +AFS + L H + +H ++ + C C K F + H
Sbjct: 689 NSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH-QAIHTGKKPYKCNECGKVFTQNAH 747
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP ++C C KAF S L H IHTGE+ + C C K F
Sbjct: 748 LANHRRIH------TGEKP--YRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFR 799
Query: 1761 QKSALQVHMKKHTGERPYK 1779
Q S L H + HTGE+PYK
Sbjct: 800 QSSNLASHHRMHTGEKPYK 818
Score = 89.0 bits (219), Expect = 4e-17
Identities = 37/91 (40%), Positives = 52/91 (57%)
Query: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK 1252
KPYKC+ECGK+FT S L H + H+G+K + C C F+ + +L +H +HTG KP+K
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1253 CPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C C FR + TH + H P K +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNE 345
Score = 85.9 bits (211), Expect = 3e-16
Identities = 36/89 (40%), Positives = 50/89 (56%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K F +++HL H R HTGEKPY+C CG+ F L +H HTG K +
Sbjct: 730 KKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRY 789
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYK 1052
C+ C F + +L H H KPYK
Sbjct: 790 KCNECGKVFRQSSNLASHHRMHTGEKPYK 818
Score = 81.6 bits (200), Expect = 6e-15
Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
EG+ ++C + +++ ++ + + +++ + H K + H Q +A
Sbjct: 198 EGKMYECNQVEKSTNNGSSVSP-LQQIPSSVQTHRS----KKYHELNHFSLLTQRRKAN- 251
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
S KP +KC+ C KAF + S L H RIH+GE+P+ C+ C K F +S L +H H
Sbjct: 252 --SCGKP--YKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH 307
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
TGE+PYKC C F S + H +R H+
Sbjct: 308 TGEKPYKCHECGKVFRHNSYLATH-RRIHT 336
Score = 48.9 bits (115), Expect = 5e-05
Identities = 21/69 (30%), Positives = 31/69 (44%)
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
K ++ K + C+ C AF+ +L H R+H+G KP+KC C F H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308
Query: 1275 KPDPKKARK 1283
P K +
Sbjct: 309 GEKPYKCHE 317
>gi|38788288 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 291 bits (744), Expect = 5e-78
Identities = 202/688 (29%), Positives = 277/688 (40%), Gaps = 128/688 (18%)
Query: 85 KCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHR 144
K G+ C C K F++ ++L +H +H E+ CSECG FT++S L +H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH- 307
Query: 145 QELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGK 204
G + + C C K F +S L H R I Y C CGK
Sbjct: 308 ---TGEKPYKCHECGKVFRHNSYLATH----------------RRIHTGEKPYKCNECGK 348
Query: 205 TFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQ 264
F+ S LT H IHTGE+PFKC+ECGK F Q L +H HTGEKP+ C C AFS
Sbjct: 349 AFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSV 408
Query: 265 KGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHV 324
+ +L H Q +H+ K Y C EC VF+ L H ++H G + A
Sbjct: 409 RSSLAIH-QTIHTGEK---PYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFS 463
Query: 325 LTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLS 383
+ + L Q ++P S V Q +L+ + +G+ P +
Sbjct: 464 MHSNL--------ATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 384 ITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAE 443
+ + +SG
Sbjct: 516 KAFSVRSSLTTHQAIHSG------------------------------------------ 533
Query: 444 QEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPY----CAKEFRKPSDLVR 499
E P K + K +K +R G+ PY C K F + S L R
Sbjct: 534 -----EKPYKCIECGKSFTQKSH------LRSHRGIHSGEKPYKCNECGKVFAQTSQLAR 582
Query: 500 HIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRL 559
H R+HT EKP+KC C RAF+ +S+LT H HTG K +KC C K F + L H R+
Sbjct: 583 HWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRI 642
Query: 560 HTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDI 618
HTG +P+ C C K F + TH H KP K + GK
Sbjct: 643 HTGEKPYKCNECGKAFSMHSNLTTHKVIHTGE----------KPYKCNQCGKV------- 685
Query: 619 PLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRS 678
+N N+ + ++PY+C C +A+ L H
Sbjct: 686 ----------------FTQNSHLA---NHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Query: 679 HTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDL 738
HTG+KP+KC++CG+ F L H R HTG K ++C C AF SL HM IH
Sbjct: 727 HTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGE 786
Query: 739 RPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+ Y C C K F+ S N H + H E
Sbjct: 787 KRYKCNECGKVFRQSSNLASHHRMHTGE 814
Score = 266 bits (681), Expect = 1e-70
Identities = 182/665 (27%), Positives = 274/665 (41%), Gaps = 85/665 (12%)
Query: 132 LQSQLAVHMEEHRQEL----AGTRQHACKACKKEFETSSELK-----------EHMKTHY 176
+ +QL V H EL + + C +K S + K ++
Sbjct: 177 MNNQLGVSFHSHLPELQLFQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYH 236
Query: 177 KIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQ 236
++ S + R + G Y C CGK F + S LT H RIH+GE+P+KCSECGK F
Sbjct: 237 ELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTV 296
Query: 237 KGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKS 296
+ L H + HTGEKP+ C C F L +H +R+H+ K Y C EC F+
Sbjct: 297 RSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATH-RRIHTGEK---PYKCNECGKAFRG 352
Query: 297 LGSLNTHISKMHMGGPQNSTSS-----TETAHVLTATLFQTLPLQQTEAQATSASSQPSS 351
+L TH +H G + T+ +H+++ T + A S SS
Sbjct: 353 HSNLTTH-QLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSS 411
Query: 352 QAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPA---- 407
A+ I +G+ P + N + + ++G
Sbjct: 412 LAIHQTI------------HTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECG 459
Query: 408 ---AAHPNDSCH--AKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMI 462
+ H N + H T + + S V + + + + E P K ++ K
Sbjct: 460 KAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFS 519
Query: 463 KKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVK 522
+ S +I +G + + C C K F + S L H IH+ EKP+KC +C + FA
Sbjct: 520 VRSSLTTHQAI--HSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQT 577
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S L H + HTG K +KC C ++FS SL H +HTG +P+ C C K FR + +
Sbjct: 578 SQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLA 637
Query: 583 THIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFF 641
TH R++ KP K GK
Sbjct: 638 TH----------RRIHTGEKPYKCNECGKA--------------------------FSMH 661
Query: 642 QSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+ + ++ ++PYKC C + + ++ HL H R+HTGEKP++C++CG+ F L
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H HTG K +KC C FT L H IH +PY C C K F+ + HM
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA 781
Query: 762 THRYE 766
H E
Sbjct: 782 IHTGE 786
Score = 255 bits (652), Expect = 2e-67
Identities = 188/672 (27%), Positives = 271/672 (40%), Gaps = 101/672 (15%)
Query: 43 LLSFPKESQFQRHMRDHERND--------------KPHRCDQCPQTFNVEFNLTLHKCTH 88
L P Q R + HE N KP++C++C + F NLT H+ H
Sbjct: 220 LQQIPSSVQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIH 279
Query: 89 SGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQEL 147
SGE P C C K F+ ++L H ++H E+ C ECG F S LA H H
Sbjct: 280 SGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIH---- 335
Query: 148 AGTRQHACKACKKEFETSSELKEHMKTHY-----------KIRVSSTRSYNR-NIDRSGF 195
G + + C C K F S L H H K+ ++ + I
Sbjct: 336 TGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEK 395
Query: 196 TYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHAC 255
Y C CGK F S L H IHTGE+P+KC+ECGK F L H HTGEKP+ C
Sbjct: 396 PYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKC 455
Query: 256 AFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNS 315
C AFS NL +H Q +H+ K + C ECS VF L H ++H G
Sbjct: 456 NECGKAFSMHSNLATH-QVIHTGTK---PFKCNECSKVFTQNSQLANH-RRIHTGEKPYK 510
Query: 316 TSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQ 374
+ A + ++L T QA + +P Q L + SG+
Sbjct: 511 CNECGKAFSVRSSL--------TTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGE 562
Query: 375 SPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSN 434
P + + + ++G P+ N D +
Sbjct: 563 KPYKCNECGKVFAQTSQLARHWRVHTG------------------EKPYKCN-DCGRAFS 603
Query: 435 EQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKP 494
+++ T + E P K + K + + + +L R G + + C C K F
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGK--VFRHNSYLATHRRIHTGEKPYKCNECGKAFSMH 661
Query: 495 SDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLK 554
S+L H IHT EKP+KC QC + F S L H +THTG K ++C C K+FS SL
Sbjct: 662 SNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLT 721
Query: 555 VHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP 614
H +HTG +P+ C C K F + H H ++ G
Sbjct: 722 THQAIHTGKKPYKCNECGKVFTQNAHLANH-------------------RRIHTG----- 757
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQ 674
++P T+ G + S + ++ ++ YKC C + +++S +L
Sbjct: 758 ------EKPYRCTECGKAFRVR-----SSLTTHMAIHTGEKRYKCNECGKVFRQSSNLAS 806
Query: 675 HIRSHTGEKPFK 686
H R HTGEKP+K
Sbjct: 807 HHRMHTGEKPYK 818
Score = 250 bits (639), Expect = 8e-66
Identities = 169/579 (29%), Positives = 245/579 (42%), Gaps = 51/579 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F + S H R H +KP++C +C +TF V NLT+H+ H+GE P C
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHS-GEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKC 315
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F S L H H G + C
Sbjct: 316 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH----TGEKPFKC 371
Query: 156 KACKKEFETSSELKEHMKTH-----YK-------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
C K F +S L H + H YK V S+ + ++ I Y C CG
Sbjct: 372 NECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECG 431
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S L RH R+HTGE+P+KC+ECGKAF+ L TH + HTG KP C C F+
Sbjct: 432 KVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFT 491
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGP-----QNSTSS 318
Q L +H +R+H+ K Y C EC F SL TH +H G + S
Sbjct: 492 QNSQLANH-RRIHTGEK---PYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSF 546
Query: 319 TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQP 378
T+ +H+ ++ S V Q +L+ V +G+ P
Sbjct: 547 TQKSHL------------RSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 379 GQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPH-----AQNP----DV 429
+ ++G H A H + P +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 430 SSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAK 489
+ ++ T + E P K ++ K + ++ L R G + + C C K
Sbjct: 655 GKAFSMHSNLTTHKVIHTGEKPYKCNQCGK--VFTQNSHLANHQRTHTGEKPYRCNECGK 712
Query: 490 EFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFST 549
F S L H IHT +KP+KC +C + F + L H + HTG K ++C C K+F
Sbjct: 713 AFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRV 772
Query: 550 SGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
SL H+ +HTG + + C C K FR S + +H H
Sbjct: 773 RSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 196 bits (497), Expect = 2e-49
Identities = 110/322 (34%), Positives = 149/322 (46%), Gaps = 10/322 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F+ +S+L +H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 423 KPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFK 482
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C+ FT N L H H KPYKC C + F + + HQ + S
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSV----RSSLTTHQAIHSGEKPYK 538
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE---ETAQLAKIRPQESATVSEKVLVQ 1141
E G ++ S R +P + +T+QLA+ + K
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDC 598
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
A DR S + ++P C C K F+ S L H RIHTGEKPYKC+ECG
Sbjct: 599 GRAFSDRSSLTFHQAIHTGEKPYK---CHECGKVFRHNSYLATHRRIHTGEKPYKCNECG 655
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F++ S L H HTG+K + C+ C F+ L H R HTG KP++C C F
Sbjct: 656 KAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFS 715
Query: 1262 TSGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 716 VRSSLTTHQAIHTGKKPYKCNE 737
Score = 192 bits (489), Expect = 2e-48
Identities = 103/321 (32%), Positives = 150/321 (46%), Gaps = 8/321 (2%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C K F ++SHL H R HTGEKPYKC CG+ F L H+ HTG K +
Sbjct: 367 KPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYK 426
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C F N L RH H KPYKC C + F ++H ++ HQ + +
Sbjct: 427 CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF--SMH--SNLATHQVIHTGTKPFK 482
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL--VQS 1142
E + + + + R +P + + + + ++ EK ++
Sbjct: 483 CNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIEC 542
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
+ S LR + E + C C K F + S L RH R+HTGEKPYKC++CG+
Sbjct: 543 GKSFTQKSHLRSHRGIHSGEKPYK--CNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGR 600
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+F+ +S+L H HTG+K + CH C F L H R+HTG KP+KC C F
Sbjct: 601 AFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSM 660
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
TH H P K +
Sbjct: 661 HSNLTTHKVIHTGEKPYKCNQ 681
Score = 186 bits (471), Expect = 2e-46
Identities = 110/317 (34%), Positives = 148/317 (46%), Gaps = 34/317 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F + SHL+ H H+GEKPYKC CG+ F + L H + HTG K +
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F+ SLT H A H KPYKC C + FR + H + H TG
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIH---------TG 645
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E + C + HS+ + + T E+ + + KV Q+
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHK------VIHTGEKPYKCNQCG---------KVFTQN- 689
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
S L + Q E + C C K+F S L H IHTG+KPYKC+ECGK
Sbjct: 690 ------SHLANHQRTHTGEKPYR--CNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKV 741
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
FT + L H + HTG+K + C C AF + SL HM +HTG K +KC C FR S
Sbjct: 742 FTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQS 801
Query: 1264 GRRKTHMQFHYKPDPKK 1280
+H + H P K
Sbjct: 802 SNLASHHRMHTGEKPYK 818
Score = 185 bits (470), Expect = 3e-46
Identities = 113/347 (32%), Positives = 162/347 (46%), Gaps = 19/347 (5%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P K ++ K + S + +I G + + C C K FR S L RH R+HT EK
Sbjct: 394 EKPYKCNECGKAFSVRSSLAIHQTIH--TGEKPYKCNECGKVFRYNSYLGRHRRVHTGEK 451
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+KC +C +AF++ S L H HTG K FKC C K F+ + L H R+HTG +P+ C
Sbjct: 452 PYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKC 511
Query: 569 PHCDKKFRTSGHRKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEP 623
C K F TH A H +K E K Q+ + G + ++P
Sbjct: 512 NECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSG-------EKP 564
Query: 624 ILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
+ G + + ++ V+ ++PYKC C RA+ L H HTGEK
Sbjct: 565 YKCNECGKV--FAQTSQLARHWR---VHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEK 619
Query: 684 PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMC 743
P+KC +CG+ F L H R HTG K +KC C AF+ +L H IH +PY C
Sbjct: 620 PYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 744 PYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSM 790
C K F + + H +TH E + + +A S+ S Q++
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAI 726
Score = 184 bits (467), Expect = 7e-46
Identities = 101/306 (33%), Positives = 147/306 (48%), Gaps = 25/306 (8%)
Query: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYC 543
C C K F + S L+ H RIHT EKP+KC +C +AF+V+S+L H HTG K +KC C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH-----FKHTELRKMR 598
K F + L H R+HTG +P+ C C K F + TH H FK E K+
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 599 HQRKPA----KVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEAD 654
Q ++ G ++P + G + S + ++ +
Sbjct: 491 TQNSQLANHRRIHTG-----------EKPYKCNECGKAFSVRS-----SLTTHQAIHSGE 534
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+PYKC C +++ + HL+ H H+GEKP+KC++CG+ F L H R HTG K +K
Sbjct: 535 KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
C C AF+ SL H IH +PY C C K F+ + H + H E + +
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 654
Query: 775 QQAASI 780
+A S+
Sbjct: 655 GKAFSM 660
Score = 183 bits (465), Expect = 1e-45
Identities = 107/324 (33%), Positives = 145/324 (44%), Gaps = 34/324 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ ++C+ C+K F ++S L H R HTGEKPYKC CG+ F L +H+ H+G K +
Sbjct: 479 KPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK 538
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C SFT L H H KPYKC C + F T +H + H TG
Sbjct: 539 CIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVH---------TG 589
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E C + SDR++ +TF + + E V +
Sbjct: 590 EKPYK--CNDCGRAFSDRSS--------LTFHQAIHTGEKPYKCHECGKVFRHNSYLATH 639
Query: 1145 EKDRISELRDKQAELQDE-PKHANC--------------CTYCPKSFKKPSDLVRHVRIH 1189
+ E K E H+N C C K F + S L H R H
Sbjct: 640 RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTH 699
Query: 1190 TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
TGEKPY+C+ECGK+F+V+S+L H HTG+K + C+ C F+ L H R+HTG K
Sbjct: 700 TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEK 759
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
P++C C FR THM H
Sbjct: 760 PYRCTECGKAFRVRSSLTTHMAIH 783
Score = 183 bits (464), Expect = 2e-45
Identities = 114/345 (33%), Positives = 152/345 (44%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F+ +S+L H R HTGEKPYKC CG+ F L +H+ HTG K F
Sbjct: 311 KPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFK 370
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGF--------RTTVH----------C 1066
C+ C FT N L H H KPYKC C + F T+H C
Sbjct: 371 CNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNEC 430
Query: 1067 KK------HMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEET 1120
K ++ RH+ V + E G + + ++P +
Sbjct: 431 GKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVF 490
Query: 1121 AQLAKIRPQESATVSEKVLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKK 1178
Q +++ EK + K S L QA E + C C KSF +
Sbjct: 491 TQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYK--CIECGKSFTQ 548
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S L H IH+GEKPYKC+ECGK F S L H + HTG+K + C+ C AFS + SL
Sbjct: 549 KSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSL 608
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H +HTG KP+KC C FR + TH + H P K +
Sbjct: 609 TFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNE 653
Score = 181 bits (458), Expect = 8e-45
Identities = 99/275 (36%), Positives = 136/275 (49%), Gaps = 27/275 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F + SQ RH R H +KP++C+ C + F+ +LT H+ H+GE P C
Sbjct: 565 YKCNECGKVFAQTSQLARHWRVHT-GEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKC 623
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + L H +H E+ C+ECG F++ S L H H G + + C
Sbjct: 624 HECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH----TGEKPYKC 679
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F +S L H +TH + Y C CGK F S LT H
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEK----------------PYRCNECGKAFSVRSSLTTH 723
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
IHTG++P+KC+ECGK F Q L H HTGEKP+ C C AF + +L +H+ +
Sbjct: 724 QAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA-I 782
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C EC VF+ +L +H +MH G
Sbjct: 783 HTGEKR---YKCNECGKVFRQSSNLASH-HRMHTG 813
Score = 180 bits (456), Expect = 1e-44
Identities = 103/316 (32%), Positives = 141/316 (44%), Gaps = 32/316 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F ++S+L H R H+GEKPYKC CG+ F L H+ HTG K +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C F N L H H KPYKC C + FR ++ HQ + +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRG----HSNLTTHQLIHTGEKPFK 370
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G + + +I+ T + +P + + V+S+
Sbjct: 371 CNECGKLFTQNS--------------HLISHWRIHTGE----KPYKCNECGKAFSVRSSL 412
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ +K + C C K F+ S L RH R+HTGEKPYKC+ECGK+F
Sbjct: 413 AIHQTIHTGEKPYK----------CNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAF 462
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
++ S L H HTG K F C+ CS F+ L H R+HTG KP+KC C F
Sbjct: 463 SMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRS 522
Query: 1265 RRKTHMQFHYKPDPKK 1280
TH H P K
Sbjct: 523 SLTTHQAIHSGEKPYK 538
Score = 149 bits (375), Expect = 3e-35
Identities = 78/218 (35%), Positives = 109/218 (50%), Gaps = 22/218 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F S H R H +KP++C++C + F++ NLT HK H+GE P C
Sbjct: 621 YKCHECGKVFRHNSYLATHRRIHT-GEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKC 679
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F++ + L H H E+ C+ECG F+++S L H H G + + C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIH----TGKKPYKC 735
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F ++ L H + H + Y C CGK F+ S LT H
Sbjct: 736 NECGKVFTQNAHLANHRRIHTGEK----------------PYRCTECGKAFRVRSSLTTH 779
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPH 253
+ IHTGE+ +KC+ECGK F Q L +H HTGEKP+
Sbjct: 780 MAIHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPY 817
Score = 127 bits (319), Expect = 1e-28
Identities = 75/273 (27%), Positives = 120/273 (43%), Gaps = 35/273 (12%)
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRK 582
S LT K ++ K +KC C K+F+ + +L H R+H+G +P+ C C K F +
Sbjct: 242 SLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLT 301
Query: 583 THIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ 642
H H ++P + G + N +
Sbjct: 302 IHQVIHTG------------------------------EKPYKCHECGKV--FRHNSYLA 329
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
++ ++ ++PYKC C +A++ +L H HTGEKPFKC++CG+ F L +
Sbjct: 330 THRR---IHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLIS 386
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H R HTG K +KC C AF+ SL H IH +PY C C K F+ + +H +
Sbjct: 387 HWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRV 446
Query: 763 HRYELAQQLQQHQQAASIDDSTVDQQSMQASTQ 795
H E + + +A S+ + Q + T+
Sbjct: 447 HTGEKPYKCNECGKAFSMHSNLATHQVIHTGTK 479
Score = 118 bits (296), Expect = 5e-26
Identities = 53/115 (46%), Positives = 64/115 (55%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S+L H RIH+GEKPYKC ECGK+FTV+S L H HTG+K + CH C
Sbjct: 259 CNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYKCHEC 318
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
F L H R+HTG KP+KC C FR TH H P K +
Sbjct: 319 GKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNE 373
Score = 117 bits (294), Expect = 8e-26
Identities = 59/148 (39%), Positives = 87/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L H + +H E+ + C C K+F + +HL+ H H
Sbjct: 507 KPYKCNECGKAFSVRSSLTTH-QAIHSGEKPYKCIECGKSFTQKSHLRSHRGIH------ 559
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C K FA+ SQL RH R+HTGE+P+ C C +AF+ +S+L H HTG
Sbjct: 560 SGEKP--YKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTG 617
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 618 EKPYKCHECGKVFRHNSYLATH-RRIHT 644
Score = 116 bits (291), Expect = 2e-25
Identities = 58/142 (40%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + VH E+ + C C KAF ++L H H
Sbjct: 423 KPYKCNECGKVFRYNSYLGRH-RRVHTGEKPYKCNECGKAFSMHSNLATHQVIH------ 475
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP FKC+ C K F + SQL H RIHTGE+P+ C C KAF+ +S+L H H+G
Sbjct: 476 TGTKP--FKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSG 533
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C FTQKS+++ H
Sbjct: 534 EKPYKCIECGKSFTQKSHLRSH 555
Score = 111 bits (278), Expect = 6e-24
Identities = 59/162 (36%), Positives = 84/162 (51%), Gaps = 21/162 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++C EC +AFS + L H K +H E+ + C C K F + +HL H +TH
Sbjct: 647 KPYKCNECGKAFSMHSNLTTH-KVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPY 705
Query: 1709 ---QAGPSLSSQKP-----------RVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
+ G + S + + +KC+ C K F + + L H RIHTGE+P+ CT
Sbjct: 706 RCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTE 765
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
C KAF +S+L HM HTGE+ YKC C F Q SN+ H
Sbjct: 766 CGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASH 807
Score = 108 bits (270), Expect = 5e-23
Identities = 51/142 (35%), Positives = 78/142 (54%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C+EC ++F+ + L H + +H E+ + C C K F + + L H + H
Sbjct: 535 KPYKCIECGKSFTQKSHLRSH-RGIHSGEKPYKCNECGKVFAQTSQLARHWRVH------ 587
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C +AF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 588 TGEKP--YKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTG 645
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTH 667
Score = 107 bits (267), Expect = 1e-22
Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF ++L H H
Sbjct: 619 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFSMHSNLTTHKVIH------ 671
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F + S L H R HTGE+P+ C C KAF+ +S+L H HTG
Sbjct: 672 TGEKP--YKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIHTG 729
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
++PYKC C FTQ +++ H +R H+
Sbjct: 730 KKPYKCNECGKVFTQNAHLANH-RRIHT 756
Score = 106 bits (265), Expect = 2e-22
Identities = 55/156 (35%), Positives = 83/156 (53%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ NL + + ++C EC + F+ + L H + +H E+ + C C K F+ ++
Sbjct: 269 NSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIH-QVIHTGEKPYKCHECGKVFRHNSY 327
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC+ C KAF S L H IHTGE+PF C C K F
Sbjct: 328 LATHRRIH------TGEKP--YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFT 379
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
Q S L H + HTGE+PYKC C F+ +S++ +H
Sbjct: 380 QNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIH 415
Score = 106 bits (265), Expect = 2e-22
Identities = 56/148 (37%), Positives = 82/148 (55%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L H + +H E+ + C C KAF+ ++L H H
Sbjct: 311 KPYKCHECGKVFRHNSYLATH-RRIHTGEKPYKCNECGKAFRGHSNLTTHQLIH------ 363
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP FKC+ C K F + S L H RIHTGE+P+ C C KAF+ +S+L +H HTG
Sbjct: 364 TGEKP--FKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTG 421
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F S + H +R H+
Sbjct: 422 EKPYKCNECGKVFRYNSYLGRH-RRVHT 448
Score = 104 bits (259), Expect = 9e-22
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C+ C K+F S+L H IHTGEKPYKC ECGK F S L H + HTG+K + C+ C
Sbjct: 287 CSECGKTFTVRSNLTIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNEC 346
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AF +L H +HTG KPFKC C F + +H + H P K +
Sbjct: 347 GKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNE 401
Score = 104 bits (259), Expect = 9e-22
Identities = 54/142 (38%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L H +H E+ C C K F + +HL H + H
Sbjct: 339 KPYKCNECGKAFRGHSNLTTHQL-IHTGEKPFKCNECGKLFTQNSHLISHWRIH------ 391
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF+ S L H IHTGE+P+ C C K F S L H + HTG
Sbjct: 392 TGEKP--YKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTG 449
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F+ SN+ H
Sbjct: 450 EKPYKCNECGKAFSMHSNLATH 471
Score = 103 bits (256), Expect = 2e-21
Identities = 50/149 (33%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Query: 932 NVTTRLIQESSQEELDLQAQGSQFLEDNE-------DQSRRSYRCDYCNKGFKKSSHLKQ 984
N+TT + + ++ G F +++ + YRC+ C K F S L
Sbjct: 663 NLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTT 722
Query: 985 HVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMAT 1044
H HTG+KPYKC CG+ F + L +H + HTG K + C+ C +F SLT HMA
Sbjct: 723 HQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAI 782
Query: 1045 HMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
H K YKC C + FR + + H + H
Sbjct: 783 HTGEKRYKCNECGKVFRQSSNLASHHRMH 811
Score = 102 bits (254), Expect = 3e-21
Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC + F+ + L+ H + +H E+ + C C KAF + L H H + +
Sbjct: 370 KCNECGKLFTQNSHLISHWR-IHTGEKPYKCNECGKAFSVRSSLAIHQTIH------TGE 422
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP +KC+ C K F S L RH R+HTGE+P+ C C KAF+ S L H HTG +P
Sbjct: 423 KP--YKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP 480
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
+KC C FTQ S + H +R H+
Sbjct: 481 FKCNECSKVFTQNSQLANH-RRIHT 504
Score = 92.0 bits (227), Expect = 5e-18
Identities = 49/139 (35%), Positives = 72/139 (51%), Gaps = 9/139 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ +LA + + ++C EC +AFS + L H + +H ++ + C C K F + H
Sbjct: 689 NSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH-QAIHTGKKPYKCNECGKVFTQNAH 747
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP ++C C KAF S L H IHTGE+ + C C K F
Sbjct: 748 LANHRRIH------TGEKP--YRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFR 799
Query: 1761 QKSALQVHMKKHTGERPYK 1779
Q S L H + HTGE+PYK
Sbjct: 800 QSSNLASHHRMHTGEKPYK 818
Score = 89.0 bits (219), Expect = 4e-17
Identities = 37/91 (40%), Positives = 52/91 (57%)
Query: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK 1252
KPYKC+ECGK+FT S L H + H+G+K + C C F+ + +L +H +HTG KP+K
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 1253 CPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C C FR + TH + H P K +
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNE 345
Score = 85.9 bits (211), Expect = 3e-16
Identities = 36/89 (40%), Positives = 50/89 (56%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K F +++HL H R HTGEKPY+C CG+ F L +H HTG K +
Sbjct: 730 KKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRY 789
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYK 1052
C+ C F + +L H H KPYK
Sbjct: 790 KCNECGKVFRQSSNLASHHRMHTGEKPYK 818
Score = 81.6 bits (200), Expect = 6e-15
Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
EG+ ++C + +++ ++ + + +++ + H K + H Q +A
Sbjct: 198 EGKMYECNQVEKSTNNGSSVSP-LQQIPSSVQTHRS----KKYHELNHFSLLTQRRKAN- 251
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
S KP +KC+ C KAF + S L H RIH+GE+P+ C+ C K F +S L +H H
Sbjct: 252 --SCGKP--YKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIH 307
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
TGE+PYKC C F S + H +R H+
Sbjct: 308 TGEKPYKCHECGKVFRHNSYLATH-RRIHT 336
Score = 48.9 bits (115), Expect = 5e-05
Identities = 21/69 (30%), Positives = 31/69 (44%)
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
K ++ K + C+ C AF+ +L H R+H+G KP+KC C F H H
Sbjct: 249 KANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHT 308
Query: 1275 KPDPKKARK 1283
P K +
Sbjct: 309 GEKPYKCHE 317
>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
[Homo sapiens]
Length = 738
Score = 267 bits (683), Expect = 6e-71
Identities = 178/640 (27%), Positives = 273/640 (42%), Gaps = 110/640 (17%)
Query: 109 KAHIMLHEK----EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFET 164
K+ I+++ + E+ CSEC F+ + L H H +++A C C K F
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIA----FGCGNCGKTFPQ 246
Query: 165 SSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERP 224
S+ H +TH + + YN C CGK F + SQLT H R HTGE+P
Sbjct: 247 KSQFITHHRTH-----TGEKPYN-----------CSQCGKAFSQKSQLTSHQRTHTGEKP 290
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
++C ECGKAF++K L +H HTGEKP+ C C AFS+K NL +H QR+H+ K
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEK---P 346
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C EC F L TH + H G S A + L + + E
Sbjct: 347 FECRECGKAFSRKSQLVTH-HRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
+ + + + S +I +G+ P Q ++ + ++G
Sbjct: 406 SECRKAFRERSSLINH-------QRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG--- 455
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSS----VSNEQTDPTDAEQEKEQESPEKLDKKEKK 460
+ P + S + ++ ++ E P + + K
Sbjct: 456 --------------------EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKA 495
Query: 461 MIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFA 520
+K S L R G + +VC C K F + S L+ H R HT EKP++C +C +AF
Sbjct: 496 FSEKLS--LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFG 553
Query: 521 VKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGH 580
KS+L H +THTG K ++C+ C K+FS L H R+HTG +P+ C C K F
Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE 613
Query: 581 RKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPI 635
H+ +H ++ E RK ++
Sbjct: 614 LIRHLRTHTGEKPYECNECRKAFREK---------------------------------- 639
Query: 636 PKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
S N+ ++ ++P++C C +A+ + HL H R+HTGEKP+ CS+C + F
Sbjct: 640 ------SSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFS 693
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
L H R HTG K ++C+ C AF+ L H H
Sbjct: 694 QKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 261 bits (667), Expect = 4e-69
Identities = 176/551 (31%), Positives = 247/551 (44%), Gaps = 59/551 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C C +FP++SQF H R H +KP+ C QC + F+ + LT H+ TH+GE P C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHT-GEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGE 295
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FSR + L +H H E+ C+ECG F+ +S L H H G + C+
Sbjct: 296 CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIH----TGEKPFECRE 351
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F S+L H +TH + + C C K F + S+L RH
Sbjct: 352 CGKAFSRKSQLVTHHRTHTGTK----------------PFGCSDCRKAFFEKSELIRHQT 395
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
IHTGE+P++CSEC KAF ++ +L H HTGEKPH C C AFSQK +L SH Q H+
Sbjct: 396 IHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH-QMTHT 454
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
K + C++C F L H + H G S A + L L
Sbjct: 455 GEK---PFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKA------FSEKLSLTN 504
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ T S+ Q+ +S +G+ P + G
Sbjct: 505 HQRIHTGEKPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFG---------- 553
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
E S L A H T + D ++++ ++ E P +
Sbjct: 554 EKSSL-----ATHQ----RTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K +K L +R G + + C C K FR+ S L+ H RIHT EKPF+C +C +
Sbjct: 605 RKAFFEKSE--LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF-- 575
AF+ KS L H +THTG K + C C K+FS L H R+HTG +P+ C C K F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQ 722
Query: 576 --RTSGHRKTH 584
+ H++TH
Sbjct: 723 KSQLINHQRTH 733
Score = 236 bits (603), Expect = 1e-61
Identities = 182/627 (29%), Positives = 253/627 (40%), Gaps = 85/627 (13%)
Query: 160 KEFETSSELKEHMKTHYK--IRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTRHI 216
K +T + LK + YK + S Y+RN R G Y C C K F K L +H
Sbjct: 169 KPEDTDTWLKYYDCDKYKESYKKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQ 226
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
H + F C CGK F QK TH HTGEKP+ C+ C AFSQK L SH QR H
Sbjct: 227 SRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSH-QRTH 285
Query: 277 SEVKNGPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+ K Y C EC F L TH + G + + +E ++++ T
Sbjct: 286 TGEK---PYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHT 342
Query: 333 --LPLQQTEA-QATSASSQPSSQ----------AVSDVIQQLLELSE---PAPVESGQSP 376
P + E +A S SQ + SD + E SE + +G+ P
Sbjct: 343 GEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKP 402
Query: 377 QPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ 436
+ ++ H + H A + +S++
Sbjct: 403 YECSECRKAFRERSSLINHQ-----------RTHTGEKPHGCIQCGKAFSQKSHLISHQM 451
Query: 437 TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSD 496
T E P K K +K L R G + + C C K F +
Sbjct: 452 THTG--------EKPFICSKCGKAFSRKSQ--LVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 497 LVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVH 556
L H RIHT EKP+ C +C +AF KS L +H +THTG K ++C C K+F SL H
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561
Query: 557 IRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVP 616
R HTG +P+ C C+K F TH +++ KP + + +
Sbjct: 562 QRTHTGEKPYECRDCEKAFSQKSQLNTH----------QRIHTGEKPYECSLCRKAF--- 608
Query: 617 DIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHI 676
++ LI L + ++PY+C C +A+++ L H
Sbjct: 609 ---FEKSELIRHLR-------------------THTGEKPYECNECRKAFREKSSLINHQ 646
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
R HTGEKPF+CS+CG+ F L H RTHTG K + C C AF+ L H IH
Sbjct: 647 RIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT 706
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+PY C C K F H +TH
Sbjct: 707 GEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 213 bits (541), Expect = 2e-54
Identities = 152/593 (25%), Positives = 243/593 (40%), Gaps = 70/593 (11%)
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
+K KK + R + + C C K F + S + H R HT EKP+ C QC +A
Sbjct: 213 RKRFSKKPSLIKHQSRHIRDIAFG-CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKA 271
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F+ KS LT+H +THTG K ++C C K+FS L H R HTG +P+ C C + F
Sbjct: 272 FSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFS-- 329
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
K+++ +H +++ KP + R GK ++ L+T
Sbjct: 330 --EKSNLINH------QRIHTGEKPFECRECGKAFS-------RKSQLVT---------- 364
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
++ + +P+ C C +A+ + L +H HTGEKP++CS+C + F
Sbjct: 365 ---------HHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L H RTHTG K C+ C AF+ L H H +P++C C K F
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475
Query: 758 KHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPE 817
+H +TH E + + +A S S + Q + + V E +
Sbjct: 476 RHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK------------- 522
Query: 818 AMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877
+ H++ + G ++P E E G + + + + ++ +E
Sbjct: 523 --AFCQKSHLISHQRTHTG----EKPYECSECGKAFGE---KSSLATHQRTHTGEKPYEC 573
Query: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQ-DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTR 936
+ F+ Q+ Q Q++ E +F ++S L T
Sbjct: 574 RDCEKAFS------QKSQLNTHQRIHTGEKPYECSLCRKAFFEKSEL---IRHLRTHTGE 624
Query: 937 LIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
E ++ + + S + + C C K F + SHL H R+HTGEKPY
Sbjct: 625 KPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYG 684
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
C C + F L +H++ HTG K + C C +F+ L H TH K
Sbjct: 685 CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 205 bits (522), Expect = 3e-52
Identities = 111/317 (35%), Positives = 150/317 (47%), Gaps = 10/317 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F + SHL H R+HTGEKPY C CGR F L +H++ HTG K F
Sbjct: 289 KPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFE 348
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ L H TH KP+ C C + F K + RHQT+ +
Sbjct: 349 CRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFE----KSELIRHQTIHTGEKPYE 404
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+E E + + +P + +Q + + + EK + S
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1145 EK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K R S+L R ++ ++P C+ C K+F + L H RIHTGEKPY C ECG
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYE---CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS L H +THTG+K + C C AF K SL H R HTG KP++C CE F
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581
Query: 1262 TSGRRKTHMQFHYKPDP 1278
+ TH + H P
Sbjct: 582 QKSQLNTHQRIHTGEKP 598
Score = 201 bits (511), Expect = 5e-51
Identities = 107/332 (32%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C + F + S+L H R HTGEKP++C+ CG+ F L +H +THTG K F
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F L RH H KPY+C C + FR + + HQ + G
Sbjct: 377 CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRE----RSSLINHQRTHTGEKPHG 432
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ G ++ S + +P + + + ++ +++ + EK S
Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492
Query: 1145 EK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K +++S ++ ++P C+ C K+F + S L+ H R HTGEKPY+C ECG
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPY---VCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS+L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFF 609
Query: 1262 TSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
H++ H P + RK SS
Sbjct: 610 EKSELIRHLRTHTGEKPYECNECRKAFREKSS 641
Score = 199 bits (507), Expect = 2e-50
Identities = 106/313 (33%), Positives = 152/313 (48%), Gaps = 12/313 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F + SHL H +HTGEKP+ C CG+ F L H++THTG K +
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
CS C +F+ SLT H H KPY C C + F H H + H P S
Sbjct: 489 CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ G E+ + + +P E+ +Q +++ + EK S
Sbjct: 549 GKAFG-----EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603
Query: 1144 AEK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K ++ +R + ++P C C K+F++ S L+ H RIHTGEKP++C EC
Sbjct: 604 CRKAFFEKSELIRHLRTHTGEKPYE---CNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ KS L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720
Query: 1261 RTSGRRKTHMQFH 1273
+ H + H
Sbjct: 721 SQKSQLINHQRTH 733
Score = 199 bits (505), Expect = 3e-50
Identities = 110/321 (34%), Positives = 152/321 (47%), Gaps = 18/321 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F++ S L H R+HTGEKP+ C CG+ F L SH+ THTG K F
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F+ L RH TH KPY+C C + F + H + H TG
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIH---------TG 511
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E +E G ++ S + +P + + + + + + EK
Sbjct: 512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPY 571
Query: 1140 VQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
EK + S+L Q E + C+ C K+F + S+L+RH+R HTGEKPY+C
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYE--CSLCRKAFFEKSELIRHLRTHTGEKPYEC 629
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+EC K+F KS+L H + HTG+K F C C AFS K L H R HTG KP+ C C
Sbjct: 630 NECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECR 689
Query: 1258 LRFRTSGRRKTHMQFHYKPDP 1278
F + H + H P
Sbjct: 690 KAFSQKSQLVNHQRIHTGEKP 710
Score = 184 bits (468), Expect = 5e-46
Identities = 141/509 (27%), Positives = 210/509 (41%), Gaps = 71/509 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F ++SQ H R H +KP+ C +C + F+ + +L H TH+GE P C
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGC 321
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------------ 143
C + FS ++L H +H E+ C ECG F+ +SQL H H
Sbjct: 322 NECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCR 381
Query: 144 -----RQEL-------AGTRQHACKACKKEFETSSELKEHMKTHYK------IRVSSTRS 185
+ EL G + + C C+K F S L H +TH I+ S
Sbjct: 382 KAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFS 441
Query: 186 YNRNIDRSGFTYS------CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
++ T++ C CGK F + SQL RH R HTGE+P++CSECGKAF++K +
Sbjct: 442 QKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGS 299
L H HTGEKP+ C+ C AF QK +L SH QR H+ K Y C+EC F S
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK---PYECSECGKAFGEKSS 557
Query: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359
L TH + H G E A + L + E + + + S++I+
Sbjct: 558 LATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIR 616
Query: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419
L + P E + + ++ S ++ ++G +
Sbjct: 617 HLRTHTGEKPYECNECRKAFREKS-------SLINHQRIHTGEKPFECSECGKAFSRKSH 669
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
PH ++ E P + K +K L R G
Sbjct: 670 LIPH-------------------QRTHTGEKPYGCSECRKAFSQKSQ--LVNHQRIHTGE 708
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
+ + C C K F + S L+ H R HT +K
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 180 bits (457), Expect = 1e-44
Identities = 140/574 (24%), Positives = 220/574 (38%), Gaps = 61/574 (10%)
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
+ C + +++ + + H GEK + C+ C FS+K +L H R ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI----A 234
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F TH + H G + S A + L T Q T
Sbjct: 235 FGCGNCGKTFPQKSQFITH-HRTHTGEKPYNCSQCGKAFSQKSQL--------TSHQRTH 285
Query: 345 ASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLS 403
+P + L +G+ P + +++ ++G
Sbjct: 286 TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345
Query: 404 SIPAAAHPNDSCHAKTSAPHAQN---------PDVSSVSNEQTDPTDAEQEKEQESPEKL 454
H + D E+++ + E P +
Sbjct: 346 PFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K ++ S L R G + H C C K F + S L+ H HT EKPF C +
Sbjct: 406 SECRKAFRERSS--LINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSK 463
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L H +THTG K ++C C K+FS SL H R+HTG +P+ C C K
Sbjct: 464 CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
F +K+H+ SH + T + ++ G+ +
Sbjct: 524 FC----QKSHLISH-QRTHTGEKPYECSECGKAFGEKS---------------------- 556
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF 694
S + + ++PY+C C +A+ + L H R HTGEKP++CS C + F
Sbjct: 557 --------SLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608
Query: 695 VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSL 754
L H+RTHTG K ++C C AF SL H IH +P+ C C K F
Sbjct: 609 FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKS 668
Query: 755 NCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
+ H +TH E + ++A S V+ Q
Sbjct: 669 HLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQ 702
Score = 170 bits (431), Expect = 1e-41
Identities = 96/315 (30%), Positives = 139/315 (44%), Gaps = 10/315 (3%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y C C K F K L +H H + + C CG+ F +H +THTG K ++CS
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCS 266
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ LT H TH KPY+C C + F H H + H + G
Sbjct: 267 QCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEKPYGCN 322
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
E G E+ + + +P + ++ +++ K S K
Sbjct: 323 ECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRK 382
Query: 1147 ---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
++ +R + ++P C+ C K+F++ S L+ H R HTGEKP+ C +CGK+
Sbjct: 383 AFFEKSELIRHQTIHTGEKPYE---CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ KS L H THTG+K F C C AFS K L H R HTG KP++C C F
Sbjct: 440 FSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEK 499
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 500 LSLTNHQRIHTGEKP 514
Score = 128 bits (322), Expect = 4e-29
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L++H + H E+ HGC C KAF + +HL H TH
Sbjct: 401 KPYECSECRKAFRERSSLINHQR-THTGEKPHGCIQCGKAFSQKSHLISHQMTH------ 453
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F C C KAF++ SQL RH R HTGE+P+ C+ C KAF++K +L H + HTG
Sbjct: 454 TGEKP--FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C+ C F QKS++ H +R H+
Sbjct: 512 EKPYVCSECGKAFCQKSHLISH-QRTHT 538
Score = 127 bits (320), Expect = 8e-29
Identities = 62/160 (38%), Positives = 95/160 (59%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G +LA + + ++C +C++AFS + L H + +H E+ + C +CRKAF
Sbjct: 553 GEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-IHTGEKPYECSLCRKAFFEK 611
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L H++TH + +KP ++C+ C KAF + S L H RIHTGE+PF C+ C KA
Sbjct: 612 SELIRHLRTH------TGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKA 663
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F++KS L H + HTGE+PY C+ C F+QKS + H +
Sbjct: 664 FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQR 703
Score = 123 bits (309), Expect = 1e-27
Identities = 67/173 (38%), Positives = 98/173 (56%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + L+ H + H E+ + C C KAF + L H +TH
Sbjct: 513 KPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFGEKSSLATHQRTH------ 565
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF++ SQL H RIHTGE+P+ C+LC KAF +KS L H++ HTG
Sbjct: 566 TGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTG 623
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+PY+C C F +KS++ H +R H+ E + G+ SR HL
Sbjct: 624 EKPYECNECRKAFREKSSLINH-QRIHT-----GEKPFECSECGKAFSRKSHL 670
Score = 118 bits (295), Expect = 6e-26
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC RAFS + L++H + +H E+ C C KAF R + L H +TH
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQR-IHTGEKPFECRECGKAFSRKSQLVTHHRTH------ 369
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP F C C KAF + S+L RH IHTGE+P+ C+ C KAF ++S+L H + HTG
Sbjct: 370 TGTKP--FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTG 427
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+P+ C C F+QKS++ H
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISH 449
Score = 112 bits (280), Expect = 3e-24
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L+ H + H E+ +GC C +AF ++L H + H
Sbjct: 289 KPYECGECGKAFSRKSHLISHWR-THTGEKPYGCNECGRAFSEKSNLINHQRIH------ 341
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F+C C KAF++ SQL H R HTG +PF C+ C KAF +KS L H HTG
Sbjct: 342 TGEKP--FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTG 399
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C F ++S++ H +R H+
Sbjct: 400 EKPYECSECRKAFRERSSLINH-QRTHT 426
Score = 112 bits (279), Expect = 4e-24
Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS L+ H H R+ GC C K F + + H +TH
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSR-HIRDIAFGCGNCGKTFPQKSQFITHHRTH------ 257
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAF++ SQL H R HTGE+P+ C C KAF++KS L H + HTG
Sbjct: 258 TGEKP--YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTG 315
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F++KSN+ H +
Sbjct: 316 EKPYGCNECGRAFSEKSNLINHQR 339
Score = 108 bits (271), Expect = 4e-23
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S + H R HTGEKPY C +CGK+F+ KS L H +THTG+K + C C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AFS K L H R HTG KP+ C C F H + H P + R+
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351
Score = 103 bits (256), Expect = 2e-21
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 13/154 (8%)
Query: 1648 NQPEKEGRAHQCLECDR---AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEH 1704
++PE + +CD+ ++ + ++++H + E+++ C CRK F + L +H
Sbjct: 168 SKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLG--EKLYECSECRKRFSKKPSLIKH 225
Query: 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSA 1764
H + F C C K F + SQ H R HTGE+P++C+ C KAF+QKS
Sbjct: 226 QSRHI--------RDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQ 277
Query: 1765 LQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
L H + HTGE+PY+C C F++KS++ H +
Sbjct: 278 LTSHQRTHTGEKPYECGECGKAFSRKSHLISHWR 311
Score = 73.6 bits (179), Expect = 2e-12
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
L K + K+ +C Y +S+KK ++ H R GEK Y+C EC K F+ K +L
Sbjct: 166 LHSKPEDTDTWLKYYDCDKY-KESYKKSQIIIYH-RNRLGEKLYECSECRKRFSKKPSLI 223
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H H F C C F K H R HTG KP+ C C F + +H +
Sbjct: 224 KHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQR 283
Query: 1272 FHYKPDP 1278
H P
Sbjct: 284 THTGEKP 290
Score = 62.0 bits (149), Expect = 5e-09
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y C C K F + S L H R HTGEKPY+C CG+ F L +H++THT K+
Sbjct: 681 KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKKS 738
>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
[Homo sapiens]
Length = 738
Score = 267 bits (683), Expect = 6e-71
Identities = 178/640 (27%), Positives = 273/640 (42%), Gaps = 110/640 (17%)
Query: 109 KAHIMLHEK----EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFET 164
K+ I+++ + E+ CSEC F+ + L H H +++A C C K F
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIA----FGCGNCGKTFPQ 246
Query: 165 SSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERP 224
S+ H +TH + + YN C CGK F + SQLT H R HTGE+P
Sbjct: 247 KSQFITHHRTH-----TGEKPYN-----------CSQCGKAFSQKSQLTSHQRTHTGEKP 290
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
++C ECGKAF++K L +H HTGEKP+ C C AFS+K NL +H QR+H+ K
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEK---P 346
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C EC F L TH + H G S A + L + + E
Sbjct: 347 FECRECGKAFSRKSQLVTH-HRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
+ + + + S +I +G+ P Q ++ + ++G
Sbjct: 406 SECRKAFRERSSLINH-------QRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG--- 455
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSS----VSNEQTDPTDAEQEKEQESPEKLDKKEKK 460
+ P + S + ++ ++ E P + + K
Sbjct: 456 --------------------EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKA 495
Query: 461 MIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFA 520
+K S L R G + +VC C K F + S L+ H R HT EKP++C +C +AF
Sbjct: 496 FSEKLS--LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFG 553
Query: 521 VKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGH 580
KS+L H +THTG K ++C+ C K+FS L H R+HTG +P+ C C K F
Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE 613
Query: 581 RKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPI 635
H+ +H ++ E RK ++
Sbjct: 614 LIRHLRTHTGEKPYECNECRKAFREK---------------------------------- 639
Query: 636 PKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
S N+ ++ ++P++C C +A+ + HL H R+HTGEKP+ CS+C + F
Sbjct: 640 ------SSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFS 693
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
L H R HTG K ++C+ C AF+ L H H
Sbjct: 694 QKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 261 bits (667), Expect = 4e-69
Identities = 176/551 (31%), Positives = 247/551 (44%), Gaps = 59/551 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C C +FP++SQF H R H +KP+ C QC + F+ + LT H+ TH+GE P C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHT-GEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGE 295
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FSR + L +H H E+ C+ECG F+ +S L H H G + C+
Sbjct: 296 CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIH----TGEKPFECRE 351
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F S+L H +TH + + C C K F + S+L RH
Sbjct: 352 CGKAFSRKSQLVTHHRTHTGTK----------------PFGCSDCRKAFFEKSELIRHQT 395
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
IHTGE+P++CSEC KAF ++ +L H HTGEKPH C C AFSQK +L SH Q H+
Sbjct: 396 IHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH-QMTHT 454
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
K + C++C F L H + H G S A + L L
Sbjct: 455 GEK---PFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKA------FSEKLSLTN 504
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ T S+ Q+ +S +G+ P + G
Sbjct: 505 HQRIHTGEKPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFG---------- 553
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
E S L A H T + D ++++ ++ E P +
Sbjct: 554 EKSSL-----ATHQ----RTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K +K L +R G + + C C K FR+ S L+ H RIHT EKPF+C +C +
Sbjct: 605 RKAFFEKSE--LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF-- 575
AF+ KS L H +THTG K + C C K+FS L H R+HTG +P+ C C K F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQ 722
Query: 576 --RTSGHRKTH 584
+ H++TH
Sbjct: 723 KSQLINHQRTH 733
Score = 236 bits (603), Expect = 1e-61
Identities = 182/627 (29%), Positives = 253/627 (40%), Gaps = 85/627 (13%)
Query: 160 KEFETSSELKEHMKTHYK--IRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTRHI 216
K +T + LK + YK + S Y+RN R G Y C C K F K L +H
Sbjct: 169 KPEDTDTWLKYYDCDKYKESYKKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQ 226
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
H + F C CGK F QK TH HTGEKP+ C+ C AFSQK L SH QR H
Sbjct: 227 SRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSH-QRTH 285
Query: 277 SEVKNGPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+ K Y C EC F L TH + G + + +E ++++ T
Sbjct: 286 TGEK---PYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHT 342
Query: 333 --LPLQQTEA-QATSASSQPSSQ----------AVSDVIQQLLELSE---PAPVESGQSP 376
P + E +A S SQ + SD + E SE + +G+ P
Sbjct: 343 GEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKP 402
Query: 377 QPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ 436
+ ++ H + H A + +S++
Sbjct: 403 YECSECRKAFRERSSLINHQ-----------RTHTGEKPHGCIQCGKAFSQKSHLISHQM 451
Query: 437 TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSD 496
T E P K K +K L R G + + C C K F +
Sbjct: 452 THTG--------EKPFICSKCGKAFSRKSQ--LVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 497 LVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVH 556
L H RIHT EKP+ C +C +AF KS L +H +THTG K ++C C K+F SL H
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561
Query: 557 IRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVP 616
R HTG +P+ C C+K F TH +++ KP + + +
Sbjct: 562 QRTHTGEKPYECRDCEKAFSQKSQLNTH----------QRIHTGEKPYECSLCRKAF--- 608
Query: 617 DIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHI 676
++ LI L + ++PY+C C +A+++ L H
Sbjct: 609 ---FEKSELIRHLR-------------------THTGEKPYECNECRKAFREKSSLINHQ 646
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
R HTGEKPF+CS+CG+ F L H RTHTG K + C C AF+ L H IH
Sbjct: 647 RIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT 706
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+PY C C K F H +TH
Sbjct: 707 GEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 213 bits (541), Expect = 2e-54
Identities = 152/593 (25%), Positives = 243/593 (40%), Gaps = 70/593 (11%)
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
+K KK + R + + C C K F + S + H R HT EKP+ C QC +A
Sbjct: 213 RKRFSKKPSLIKHQSRHIRDIAFG-CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKA 271
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F+ KS LT+H +THTG K ++C C K+FS L H R HTG +P+ C C + F
Sbjct: 272 FSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFS-- 329
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
K+++ +H +++ KP + R GK ++ L+T
Sbjct: 330 --EKSNLINH------QRIHTGEKPFECRECGKAFS-------RKSQLVT---------- 364
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
++ + +P+ C C +A+ + L +H HTGEKP++CS+C + F
Sbjct: 365 ---------HHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L H RTHTG K C+ C AF+ L H H +P++C C K F
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475
Query: 758 KHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPE 817
+H +TH E + + +A S S + Q + + V E +
Sbjct: 476 RHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK------------- 522
Query: 818 AMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877
+ H++ + G ++P E E G + + + + ++ +E
Sbjct: 523 --AFCQKSHLISHQRTHTG----EKPYECSECGKAFGE---KSSLATHQRTHTGEKPYEC 573
Query: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQ-DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTR 936
+ F+ Q+ Q Q++ E +F ++S L T
Sbjct: 574 RDCEKAFS------QKSQLNTHQRIHTGEKPYECSLCRKAFFEKSEL---IRHLRTHTGE 624
Query: 937 LIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
E ++ + + S + + C C K F + SHL H R+HTGEKPY
Sbjct: 625 KPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYG 684
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
C C + F L +H++ HTG K + C C +F+ L H TH K
Sbjct: 685 CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 205 bits (522), Expect = 3e-52
Identities = 111/317 (35%), Positives = 150/317 (47%), Gaps = 10/317 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F + SHL H R+HTGEKPY C CGR F L +H++ HTG K F
Sbjct: 289 KPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFE 348
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ L H TH KP+ C C + F K + RHQT+ +
Sbjct: 349 CRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFE----KSELIRHQTIHTGEKPYE 404
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+E E + + +P + +Q + + + EK + S
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1145 EK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K R S+L R ++ ++P C+ C K+F + L H RIHTGEKPY C ECG
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYE---CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS L H +THTG+K + C C AF K SL H R HTG KP++C CE F
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581
Query: 1262 TSGRRKTHMQFHYKPDP 1278
+ TH + H P
Sbjct: 582 QKSQLNTHQRIHTGEKP 598
Score = 201 bits (511), Expect = 5e-51
Identities = 107/332 (32%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C + F + S+L H R HTGEKP++C+ CG+ F L +H +THTG K F
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F L RH H KPY+C C + FR + + HQ + G
Sbjct: 377 CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRE----RSSLINHQRTHTGEKPHG 432
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ G ++ S + +P + + + ++ +++ + EK S
Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492
Query: 1145 EK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K +++S ++ ++P C+ C K+F + S L+ H R HTGEKPY+C ECG
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPY---VCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS+L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFF 609
Query: 1262 TSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
H++ H P + RK SS
Sbjct: 610 EKSELIRHLRTHTGEKPYECNECRKAFREKSS 641
Score = 199 bits (507), Expect = 2e-50
Identities = 106/313 (33%), Positives = 152/313 (48%), Gaps = 12/313 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F + SHL H +HTGEKP+ C CG+ F L H++THTG K +
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
CS C +F+ SLT H H KPY C C + F H H + H P S
Sbjct: 489 CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ G E+ + + +P E+ +Q +++ + EK S
Sbjct: 549 GKAFG-----EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603
Query: 1144 AEK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K ++ +R + ++P C C K+F++ S L+ H RIHTGEKP++C EC
Sbjct: 604 CRKAFFEKSELIRHLRTHTGEKPYE---CNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ KS L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720
Query: 1261 RTSGRRKTHMQFH 1273
+ H + H
Sbjct: 721 SQKSQLINHQRTH 733
Score = 199 bits (505), Expect = 3e-50
Identities = 110/321 (34%), Positives = 152/321 (47%), Gaps = 18/321 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F++ S L H R+HTGEKP+ C CG+ F L SH+ THTG K F
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F+ L RH TH KPY+C C + F + H + H TG
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIH---------TG 511
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E +E G ++ S + +P + + + + + + EK
Sbjct: 512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPY 571
Query: 1140 VQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
EK + S+L Q E + C+ C K+F + S+L+RH+R HTGEKPY+C
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYE--CSLCRKAFFEKSELIRHLRTHTGEKPYEC 629
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+EC K+F KS+L H + HTG+K F C C AFS K L H R HTG KP+ C C
Sbjct: 630 NECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECR 689
Query: 1258 LRFRTSGRRKTHMQFHYKPDP 1278
F + H + H P
Sbjct: 690 KAFSQKSQLVNHQRIHTGEKP 710
Score = 184 bits (468), Expect = 5e-46
Identities = 141/509 (27%), Positives = 210/509 (41%), Gaps = 71/509 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F ++SQ H R H +KP+ C +C + F+ + +L H TH+GE P C
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGC 321
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------------ 143
C + FS ++L H +H E+ C ECG F+ +SQL H H
Sbjct: 322 NECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCR 381
Query: 144 -----RQEL-------AGTRQHACKACKKEFETSSELKEHMKTHYK------IRVSSTRS 185
+ EL G + + C C+K F S L H +TH I+ S
Sbjct: 382 KAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFS 441
Query: 186 YNRNIDRSGFTYS------CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
++ T++ C CGK F + SQL RH R HTGE+P++CSECGKAF++K +
Sbjct: 442 QKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGS 299
L H HTGEKP+ C+ C AF QK +L SH QR H+ K Y C+EC F S
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK---PYECSECGKAFGEKSS 557
Query: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359
L TH + H G E A + L + E + + + S++I+
Sbjct: 558 LATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIR 616
Query: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419
L + P E + + ++ S ++ ++G +
Sbjct: 617 HLRTHTGEKPYECNECRKAFREKS-------SLINHQRIHTGEKPFECSECGKAFSRKSH 669
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
PH ++ E P + K +K L R G
Sbjct: 670 LIPH-------------------QRTHTGEKPYGCSECRKAFSQKSQ--LVNHQRIHTGE 708
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
+ + C C K F + S L+ H R HT +K
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 180 bits (457), Expect = 1e-44
Identities = 140/574 (24%), Positives = 220/574 (38%), Gaps = 61/574 (10%)
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
+ C + +++ + + H GEK + C+ C FS+K +L H R ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI----A 234
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F TH + H G + S A + L T Q T
Sbjct: 235 FGCGNCGKTFPQKSQFITH-HRTHTGEKPYNCSQCGKAFSQKSQL--------TSHQRTH 285
Query: 345 ASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLS 403
+P + L +G+ P + +++ ++G
Sbjct: 286 TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345
Query: 404 SIPAAAHPNDSCHAKTSAPHAQN---------PDVSSVSNEQTDPTDAEQEKEQESPEKL 454
H + D E+++ + E P +
Sbjct: 346 PFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K ++ S L R G + H C C K F + S L+ H HT EKPF C +
Sbjct: 406 SECRKAFRERSS--LINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSK 463
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L H +THTG K ++C C K+FS SL H R+HTG +P+ C C K
Sbjct: 464 CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
F +K+H+ SH + T + ++ G+ +
Sbjct: 524 FC----QKSHLISH-QRTHTGEKPYECSECGKAFGEKS---------------------- 556
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF 694
S + + ++PY+C C +A+ + L H R HTGEKP++CS C + F
Sbjct: 557 --------SLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608
Query: 695 VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSL 754
L H+RTHTG K ++C C AF SL H IH +P+ C C K F
Sbjct: 609 FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKS 668
Query: 755 NCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
+ H +TH E + ++A S V+ Q
Sbjct: 669 HLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQ 702
Score = 170 bits (431), Expect = 1e-41
Identities = 96/315 (30%), Positives = 139/315 (44%), Gaps = 10/315 (3%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y C C K F K L +H H + + C CG+ F +H +THTG K ++CS
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCS 266
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ LT H TH KPY+C C + F H H + H + G
Sbjct: 267 QCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEKPYGCN 322
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
E G E+ + + +P + ++ +++ K S K
Sbjct: 323 ECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRK 382
Query: 1147 ---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
++ +R + ++P C+ C K+F++ S L+ H R HTGEKP+ C +CGK+
Sbjct: 383 AFFEKSELIRHQTIHTGEKPYE---CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ KS L H THTG+K F C C AFS K L H R HTG KP++C C F
Sbjct: 440 FSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEK 499
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 500 LSLTNHQRIHTGEKP 514
Score = 128 bits (322), Expect = 4e-29
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L++H + H E+ HGC C KAF + +HL H TH
Sbjct: 401 KPYECSECRKAFRERSSLINHQR-THTGEKPHGCIQCGKAFSQKSHLISHQMTH------ 453
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F C C KAF++ SQL RH R HTGE+P+ C+ C KAF++K +L H + HTG
Sbjct: 454 TGEKP--FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C+ C F QKS++ H +R H+
Sbjct: 512 EKPYVCSECGKAFCQKSHLISH-QRTHT 538
Score = 127 bits (320), Expect = 8e-29
Identities = 62/160 (38%), Positives = 95/160 (59%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G +LA + + ++C +C++AFS + L H + +H E+ + C +CRKAF
Sbjct: 553 GEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-IHTGEKPYECSLCRKAFFEK 611
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L H++TH + +KP ++C+ C KAF + S L H RIHTGE+PF C+ C KA
Sbjct: 612 SELIRHLRTH------TGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKA 663
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F++KS L H + HTGE+PY C+ C F+QKS + H +
Sbjct: 664 FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQR 703
Score = 123 bits (309), Expect = 1e-27
Identities = 67/173 (38%), Positives = 98/173 (56%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + L+ H + H E+ + C C KAF + L H +TH
Sbjct: 513 KPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFGEKSSLATHQRTH------ 565
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF++ SQL H RIHTGE+P+ C+LC KAF +KS L H++ HTG
Sbjct: 566 TGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTG 623
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+PY+C C F +KS++ H +R H+ E + G+ SR HL
Sbjct: 624 EKPYECNECRKAFREKSSLINH-QRIHT-----GEKPFECSECGKAFSRKSHL 670
Score = 118 bits (295), Expect = 6e-26
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC RAFS + L++H + +H E+ C C KAF R + L H +TH
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQR-IHTGEKPFECRECGKAFSRKSQLVTHHRTH------ 369
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP F C C KAF + S+L RH IHTGE+P+ C+ C KAF ++S+L H + HTG
Sbjct: 370 TGTKP--FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTG 427
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+P+ C C F+QKS++ H
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISH 449
Score = 112 bits (280), Expect = 3e-24
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L+ H + H E+ +GC C +AF ++L H + H
Sbjct: 289 KPYECGECGKAFSRKSHLISHWR-THTGEKPYGCNECGRAFSEKSNLINHQRIH------ 341
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F+C C KAF++ SQL H R HTG +PF C+ C KAF +KS L H HTG
Sbjct: 342 TGEKP--FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTG 399
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C F ++S++ H +R H+
Sbjct: 400 EKPYECSECRKAFRERSSLINH-QRTHT 426
Score = 112 bits (279), Expect = 4e-24
Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS L+ H H R+ GC C K F + + H +TH
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSR-HIRDIAFGCGNCGKTFPQKSQFITHHRTH------ 257
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAF++ SQL H R HTGE+P+ C C KAF++KS L H + HTG
Sbjct: 258 TGEKP--YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTG 315
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F++KSN+ H +
Sbjct: 316 EKPYGCNECGRAFSEKSNLINHQR 339
Score = 108 bits (271), Expect = 4e-23
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S + H R HTGEKPY C +CGK+F+ KS L H +THTG+K + C C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AFS K L H R HTG KP+ C C F H + H P + R+
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351
Score = 103 bits (256), Expect = 2e-21
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 13/154 (8%)
Query: 1648 NQPEKEGRAHQCLECDR---AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEH 1704
++PE + +CD+ ++ + ++++H + E+++ C CRK F + L +H
Sbjct: 168 SKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLG--EKLYECSECRKRFSKKPSLIKH 225
Query: 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSA 1764
H + F C C K F + SQ H R HTGE+P++C+ C KAF+QKS
Sbjct: 226 QSRHI--------RDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQ 277
Query: 1765 LQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
L H + HTGE+PY+C C F++KS++ H +
Sbjct: 278 LTSHQRTHTGEKPYECGECGKAFSRKSHLISHWR 311
Score = 73.6 bits (179), Expect = 2e-12
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
L K + K+ +C Y +S+KK ++ H R GEK Y+C EC K F+ K +L
Sbjct: 166 LHSKPEDTDTWLKYYDCDKY-KESYKKSQIIIYH-RNRLGEKLYECSECRKRFSKKPSLI 223
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H H F C C F K H R HTG KP+ C C F + +H +
Sbjct: 224 KHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQR 283
Query: 1272 FHYKPDP 1278
H P
Sbjct: 284 THTGEKP 290
Score = 62.0 bits (149), Expect = 5e-09
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y C C K F + S L H R HTGEKPY+C CG+ F L +H++THT K+
Sbjct: 681 KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKKS 738
>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
[Homo sapiens]
Length = 738
Score = 267 bits (683), Expect = 6e-71
Identities = 178/640 (27%), Positives = 273/640 (42%), Gaps = 110/640 (17%)
Query: 109 KAHIMLHEK----EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFET 164
K+ I+++ + E+ CSEC F+ + L H H +++A C C K F
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIA----FGCGNCGKTFPQ 246
Query: 165 SSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERP 224
S+ H +TH + + YN C CGK F + SQLT H R HTGE+P
Sbjct: 247 KSQFITHHRTH-----TGEKPYN-----------CSQCGKAFSQKSQLTSHQRTHTGEKP 290
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
++C ECGKAF++K L +H HTGEKP+ C C AFS+K NL +H QR+H+ K
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEK---P 346
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C EC F L TH + H G S A + L + + E
Sbjct: 347 FECRECGKAFSRKSQLVTH-HRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
+ + + + S +I +G+ P Q ++ + ++G
Sbjct: 406 SECRKAFRERSSLINH-------QRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG--- 455
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSS----VSNEQTDPTDAEQEKEQESPEKLDKKEKK 460
+ P + S + ++ ++ E P + + K
Sbjct: 456 --------------------EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKA 495
Query: 461 MIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFA 520
+K S L R G + +VC C K F + S L+ H R HT EKP++C +C +AF
Sbjct: 496 FSEKLS--LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFG 553
Query: 521 VKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGH 580
KS+L H +THTG K ++C+ C K+FS L H R+HTG +P+ C C K F
Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE 613
Query: 581 RKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPI 635
H+ +H ++ E RK ++
Sbjct: 614 LIRHLRTHTGEKPYECNECRKAFREK---------------------------------- 639
Query: 636 PKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
S N+ ++ ++P++C C +A+ + HL H R+HTGEKP+ CS+C + F
Sbjct: 640 ------SSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFS 693
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
L H R HTG K ++C+ C AF+ L H H
Sbjct: 694 QKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 261 bits (667), Expect = 4e-69
Identities = 176/551 (31%), Positives = 247/551 (44%), Gaps = 59/551 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C C +FP++SQF H R H +KP+ C QC + F+ + LT H+ TH+GE P C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHT-GEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGE 295
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FSR + L +H H E+ C+ECG F+ +S L H H G + C+
Sbjct: 296 CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIH----TGEKPFECRE 351
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F S+L H +TH + + C C K F + S+L RH
Sbjct: 352 CGKAFSRKSQLVTHHRTHTGTK----------------PFGCSDCRKAFFEKSELIRHQT 395
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
IHTGE+P++CSEC KAF ++ +L H HTGEKPH C C AFSQK +L SH Q H+
Sbjct: 396 IHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH-QMTHT 454
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
K + C++C F L H + H G S A + L L
Sbjct: 455 GEK---PFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKA------FSEKLSLTN 504
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ T S+ Q+ +S +G+ P + G
Sbjct: 505 HQRIHTGEKPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFG---------- 553
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
E S L A H T + D ++++ ++ E P +
Sbjct: 554 EKSSL-----ATHQ----RTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K +K L +R G + + C C K FR+ S L+ H RIHT EKPF+C +C +
Sbjct: 605 RKAFFEKSE--LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF-- 575
AF+ KS L H +THTG K + C C K+FS L H R+HTG +P+ C C K F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQ 722
Query: 576 --RTSGHRKTH 584
+ H++TH
Sbjct: 723 KSQLINHQRTH 733
Score = 236 bits (603), Expect = 1e-61
Identities = 182/627 (29%), Positives = 253/627 (40%), Gaps = 85/627 (13%)
Query: 160 KEFETSSELKEHMKTHYK--IRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTRHI 216
K +T + LK + YK + S Y+RN R G Y C C K F K L +H
Sbjct: 169 KPEDTDTWLKYYDCDKYKESYKKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQ 226
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
H + F C CGK F QK TH HTGEKP+ C+ C AFSQK L SH QR H
Sbjct: 227 SRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSH-QRTH 285
Query: 277 SEVKNGPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+ K Y C EC F L TH + G + + +E ++++ T
Sbjct: 286 TGEK---PYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHT 342
Query: 333 --LPLQQTEA-QATSASSQPSSQ----------AVSDVIQQLLELSE---PAPVESGQSP 376
P + E +A S SQ + SD + E SE + +G+ P
Sbjct: 343 GEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKP 402
Query: 377 QPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ 436
+ ++ H + H A + +S++
Sbjct: 403 YECSECRKAFRERSSLINHQ-----------RTHTGEKPHGCIQCGKAFSQKSHLISHQM 451
Query: 437 TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSD 496
T E P K K +K L R G + + C C K F +
Sbjct: 452 THTG--------EKPFICSKCGKAFSRKSQ--LVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 497 LVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVH 556
L H RIHT EKP+ C +C +AF KS L +H +THTG K ++C C K+F SL H
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561
Query: 557 IRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVP 616
R HTG +P+ C C+K F TH +++ KP + + +
Sbjct: 562 QRTHTGEKPYECRDCEKAFSQKSQLNTH----------QRIHTGEKPYECSLCRKAF--- 608
Query: 617 DIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHI 676
++ LI L + ++PY+C C +A+++ L H
Sbjct: 609 ---FEKSELIRHLR-------------------THTGEKPYECNECRKAFREKSSLINHQ 646
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
R HTGEKPF+CS+CG+ F L H RTHTG K + C C AF+ L H IH
Sbjct: 647 RIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT 706
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+PY C C K F H +TH
Sbjct: 707 GEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 213 bits (541), Expect = 2e-54
Identities = 152/593 (25%), Positives = 243/593 (40%), Gaps = 70/593 (11%)
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
+K KK + R + + C C K F + S + H R HT EKP+ C QC +A
Sbjct: 213 RKRFSKKPSLIKHQSRHIRDIAFG-CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKA 271
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F+ KS LT+H +THTG K ++C C K+FS L H R HTG +P+ C C + F
Sbjct: 272 FSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFS-- 329
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
K+++ +H +++ KP + R GK ++ L+T
Sbjct: 330 --EKSNLINH------QRIHTGEKPFECRECGKAFS-------RKSQLVT---------- 364
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
++ + +P+ C C +A+ + L +H HTGEKP++CS+C + F
Sbjct: 365 ---------HHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L H RTHTG K C+ C AF+ L H H +P++C C K F
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475
Query: 758 KHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPE 817
+H +TH E + + +A S S + Q + + V E +
Sbjct: 476 RHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK------------- 522
Query: 818 AMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877
+ H++ + G ++P E E G + + + + ++ +E
Sbjct: 523 --AFCQKSHLISHQRTHTG----EKPYECSECGKAFGE---KSSLATHQRTHTGEKPYEC 573
Query: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQ-DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTR 936
+ F+ Q+ Q Q++ E +F ++S L T
Sbjct: 574 RDCEKAFS------QKSQLNTHQRIHTGEKPYECSLCRKAFFEKSEL---IRHLRTHTGE 624
Query: 937 LIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
E ++ + + S + + C C K F + SHL H R+HTGEKPY
Sbjct: 625 KPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYG 684
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
C C + F L +H++ HTG K + C C +F+ L H TH K
Sbjct: 685 CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 205 bits (522), Expect = 3e-52
Identities = 111/317 (35%), Positives = 150/317 (47%), Gaps = 10/317 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F + SHL H R+HTGEKPY C CGR F L +H++ HTG K F
Sbjct: 289 KPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFE 348
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ L H TH KP+ C C + F K + RHQT+ +
Sbjct: 349 CRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFE----KSELIRHQTIHTGEKPYE 404
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+E E + + +P + +Q + + + EK + S
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1145 EK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K R S+L R ++ ++P C+ C K+F + L H RIHTGEKPY C ECG
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYE---CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS L H +THTG+K + C C AF K SL H R HTG KP++C CE F
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581
Query: 1262 TSGRRKTHMQFHYKPDP 1278
+ TH + H P
Sbjct: 582 QKSQLNTHQRIHTGEKP 598
Score = 201 bits (511), Expect = 5e-51
Identities = 107/332 (32%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C + F + S+L H R HTGEKP++C+ CG+ F L +H +THTG K F
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F L RH H KPY+C C + FR + + HQ + G
Sbjct: 377 CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRE----RSSLINHQRTHTGEKPHG 432
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ G ++ S + +P + + + ++ +++ + EK S
Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492
Query: 1145 EK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K +++S ++ ++P C+ C K+F + S L+ H R HTGEKPY+C ECG
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPY---VCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS+L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFF 609
Query: 1262 TSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
H++ H P + RK SS
Sbjct: 610 EKSELIRHLRTHTGEKPYECNECRKAFREKSS 641
Score = 199 bits (507), Expect = 2e-50
Identities = 106/313 (33%), Positives = 152/313 (48%), Gaps = 12/313 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F + SHL H +HTGEKP+ C CG+ F L H++THTG K +
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
CS C +F+ SLT H H KPY C C + F H H + H P S
Sbjct: 489 CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ G E+ + + +P E+ +Q +++ + EK S
Sbjct: 549 GKAFG-----EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603
Query: 1144 AEK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K ++ +R + ++P C C K+F++ S L+ H RIHTGEKP++C EC
Sbjct: 604 CRKAFFEKSELIRHLRTHTGEKPYE---CNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ KS L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720
Query: 1261 RTSGRRKTHMQFH 1273
+ H + H
Sbjct: 721 SQKSQLINHQRTH 733
Score = 199 bits (505), Expect = 3e-50
Identities = 110/321 (34%), Positives = 152/321 (47%), Gaps = 18/321 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F++ S L H R+HTGEKP+ C CG+ F L SH+ THTG K F
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F+ L RH TH KPY+C C + F + H + H TG
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIH---------TG 511
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E +E G ++ S + +P + + + + + + EK
Sbjct: 512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPY 571
Query: 1140 VQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
EK + S+L Q E + C+ C K+F + S+L+RH+R HTGEKPY+C
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYE--CSLCRKAFFEKSELIRHLRTHTGEKPYEC 629
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+EC K+F KS+L H + HTG+K F C C AFS K L H R HTG KP+ C C
Sbjct: 630 NECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECR 689
Query: 1258 LRFRTSGRRKTHMQFHYKPDP 1278
F + H + H P
Sbjct: 690 KAFSQKSQLVNHQRIHTGEKP 710
Score = 184 bits (468), Expect = 5e-46
Identities = 141/509 (27%), Positives = 210/509 (41%), Gaps = 71/509 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F ++SQ H R H +KP+ C +C + F+ + +L H TH+GE P C
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGC 321
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------------ 143
C + FS ++L H +H E+ C ECG F+ +SQL H H
Sbjct: 322 NECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCR 381
Query: 144 -----RQEL-------AGTRQHACKACKKEFETSSELKEHMKTHYK------IRVSSTRS 185
+ EL G + + C C+K F S L H +TH I+ S
Sbjct: 382 KAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFS 441
Query: 186 YNRNIDRSGFTYS------CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
++ T++ C CGK F + SQL RH R HTGE+P++CSECGKAF++K +
Sbjct: 442 QKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGS 299
L H HTGEKP+ C+ C AF QK +L SH QR H+ K Y C+EC F S
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK---PYECSECGKAFGEKSS 557
Query: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359
L TH + H G E A + L + E + + + S++I+
Sbjct: 558 LATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIR 616
Query: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419
L + P E + + ++ S ++ ++G +
Sbjct: 617 HLRTHTGEKPYECNECRKAFREKS-------SLINHQRIHTGEKPFECSECGKAFSRKSH 669
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
PH ++ E P + K +K L R G
Sbjct: 670 LIPH-------------------QRTHTGEKPYGCSECRKAFSQKSQ--LVNHQRIHTGE 708
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
+ + C C K F + S L+ H R HT +K
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 180 bits (457), Expect = 1e-44
Identities = 140/574 (24%), Positives = 220/574 (38%), Gaps = 61/574 (10%)
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
+ C + +++ + + H GEK + C+ C FS+K +L H R ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI----A 234
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F TH + H G + S A + L T Q T
Sbjct: 235 FGCGNCGKTFPQKSQFITH-HRTHTGEKPYNCSQCGKAFSQKSQL--------TSHQRTH 285
Query: 345 ASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLS 403
+P + L +G+ P + +++ ++G
Sbjct: 286 TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345
Query: 404 SIPAAAHPNDSCHAKTSAPHAQN---------PDVSSVSNEQTDPTDAEQEKEQESPEKL 454
H + D E+++ + E P +
Sbjct: 346 PFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K ++ S L R G + H C C K F + S L+ H HT EKPF C +
Sbjct: 406 SECRKAFRERSS--LINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSK 463
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L H +THTG K ++C C K+FS SL H R+HTG +P+ C C K
Sbjct: 464 CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
F +K+H+ SH + T + ++ G+ +
Sbjct: 524 FC----QKSHLISH-QRTHTGEKPYECSECGKAFGEKS---------------------- 556
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF 694
S + + ++PY+C C +A+ + L H R HTGEKP++CS C + F
Sbjct: 557 --------SLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608
Query: 695 VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSL 754
L H+RTHTG K ++C C AF SL H IH +P+ C C K F
Sbjct: 609 FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKS 668
Query: 755 NCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
+ H +TH E + ++A S V+ Q
Sbjct: 669 HLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQ 702
Score = 170 bits (431), Expect = 1e-41
Identities = 96/315 (30%), Positives = 139/315 (44%), Gaps = 10/315 (3%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y C C K F K L +H H + + C CG+ F +H +THTG K ++CS
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCS 266
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ LT H TH KPY+C C + F H H + H + G
Sbjct: 267 QCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEKPYGCN 322
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
E G E+ + + +P + ++ +++ K S K
Sbjct: 323 ECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRK 382
Query: 1147 ---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
++ +R + ++P C+ C K+F++ S L+ H R HTGEKP+ C +CGK+
Sbjct: 383 AFFEKSELIRHQTIHTGEKPYE---CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ KS L H THTG+K F C C AFS K L H R HTG KP++C C F
Sbjct: 440 FSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEK 499
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 500 LSLTNHQRIHTGEKP 514
Score = 128 bits (322), Expect = 4e-29
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L++H + H E+ HGC C KAF + +HL H TH
Sbjct: 401 KPYECSECRKAFRERSSLINHQR-THTGEKPHGCIQCGKAFSQKSHLISHQMTH------ 453
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F C C KAF++ SQL RH R HTGE+P+ C+ C KAF++K +L H + HTG
Sbjct: 454 TGEKP--FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C+ C F QKS++ H +R H+
Sbjct: 512 EKPYVCSECGKAFCQKSHLISH-QRTHT 538
Score = 127 bits (320), Expect = 8e-29
Identities = 62/160 (38%), Positives = 95/160 (59%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G +LA + + ++C +C++AFS + L H + +H E+ + C +CRKAF
Sbjct: 553 GEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-IHTGEKPYECSLCRKAFFEK 611
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L H++TH + +KP ++C+ C KAF + S L H RIHTGE+PF C+ C KA
Sbjct: 612 SELIRHLRTH------TGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKA 663
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F++KS L H + HTGE+PY C+ C F+QKS + H +
Sbjct: 664 FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQR 703
Score = 123 bits (309), Expect = 1e-27
Identities = 67/173 (38%), Positives = 98/173 (56%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + L+ H + H E+ + C C KAF + L H +TH
Sbjct: 513 KPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFGEKSSLATHQRTH------ 565
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF++ SQL H RIHTGE+P+ C+LC KAF +KS L H++ HTG
Sbjct: 566 TGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTG 623
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+PY+C C F +KS++ H +R H+ E + G+ SR HL
Sbjct: 624 EKPYECNECRKAFREKSSLINH-QRIHT-----GEKPFECSECGKAFSRKSHL 670
Score = 118 bits (295), Expect = 6e-26
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC RAFS + L++H + +H E+ C C KAF R + L H +TH
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQR-IHTGEKPFECRECGKAFSRKSQLVTHHRTH------ 369
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP F C C KAF + S+L RH IHTGE+P+ C+ C KAF ++S+L H + HTG
Sbjct: 370 TGTKP--FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTG 427
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+P+ C C F+QKS++ H
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISH 449
Score = 112 bits (280), Expect = 3e-24
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L+ H + H E+ +GC C +AF ++L H + H
Sbjct: 289 KPYECGECGKAFSRKSHLISHWR-THTGEKPYGCNECGRAFSEKSNLINHQRIH------ 341
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F+C C KAF++ SQL H R HTG +PF C+ C KAF +KS L H HTG
Sbjct: 342 TGEKP--FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTG 399
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C F ++S++ H +R H+
Sbjct: 400 EKPYECSECRKAFRERSSLINH-QRTHT 426
Score = 112 bits (279), Expect = 4e-24
Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS L+ H H R+ GC C K F + + H +TH
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSR-HIRDIAFGCGNCGKTFPQKSQFITHHRTH------ 257
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAF++ SQL H R HTGE+P+ C C KAF++KS L H + HTG
Sbjct: 258 TGEKP--YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTG 315
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F++KSN+ H +
Sbjct: 316 EKPYGCNECGRAFSEKSNLINHQR 339
Score = 108 bits (271), Expect = 4e-23
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S + H R HTGEKPY C +CGK+F+ KS L H +THTG+K + C C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AFS K L H R HTG KP+ C C F H + H P + R+
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351
Score = 103 bits (256), Expect = 2e-21
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 13/154 (8%)
Query: 1648 NQPEKEGRAHQCLECDR---AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEH 1704
++PE + +CD+ ++ + ++++H + E+++ C CRK F + L +H
Sbjct: 168 SKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLG--EKLYECSECRKRFSKKPSLIKH 225
Query: 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSA 1764
H + F C C K F + SQ H R HTGE+P++C+ C KAF+QKS
Sbjct: 226 QSRHI--------RDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQ 277
Query: 1765 LQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
L H + HTGE+PY+C C F++KS++ H +
Sbjct: 278 LTSHQRTHTGEKPYECGECGKAFSRKSHLISHWR 311
Score = 73.6 bits (179), Expect = 2e-12
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
L K + K+ +C Y +S+KK ++ H R GEK Y+C EC K F+ K +L
Sbjct: 166 LHSKPEDTDTWLKYYDCDKY-KESYKKSQIIIYH-RNRLGEKLYECSECRKRFSKKPSLI 223
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H H F C C F K H R HTG KP+ C C F + +H +
Sbjct: 224 KHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQR 283
Query: 1272 FHYKPDP 1278
H P
Sbjct: 284 THTGEKP 290
Score = 62.0 bits (149), Expect = 5e-09
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y C C K F + S L H R HTGEKPY+C CG+ F L +H++THT K+
Sbjct: 681 KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKKS 738
>gi|188497655 zinc finger protein 84 [Homo sapiens]
Length = 738
Score = 267 bits (683), Expect = 6e-71
Identities = 178/640 (27%), Positives = 273/640 (42%), Gaps = 110/640 (17%)
Query: 109 KAHIMLHEK----EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFET 164
K+ I+++ + E+ CSEC F+ + L H H +++A C C K F
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIA----FGCGNCGKTFPQ 246
Query: 165 SSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERP 224
S+ H +TH + + YN C CGK F + SQLT H R HTGE+P
Sbjct: 247 KSQFITHHRTH-----TGEKPYN-----------CSQCGKAFSQKSQLTSHQRTHTGEKP 290
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
++C ECGKAF++K L +H HTGEKP+ C C AFS+K NL +H QR+H+ K
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEK---P 346
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C EC F L TH + H G S A + L + + E
Sbjct: 347 FECRECGKAFSRKSQLVTH-HRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
+ + + + S +I +G+ P Q ++ + ++G
Sbjct: 406 SECRKAFRERSSLINH-------QRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG--- 455
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSS----VSNEQTDPTDAEQEKEQESPEKLDKKEKK 460
+ P + S + ++ ++ E P + + K
Sbjct: 456 --------------------EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKA 495
Query: 461 MIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFA 520
+K S L R G + +VC C K F + S L+ H R HT EKP++C +C +AF
Sbjct: 496 FSEKLS--LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFG 553
Query: 521 VKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGH 580
KS+L H +THTG K ++C+ C K+FS L H R+HTG +P+ C C K F
Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE 613
Query: 581 RKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPI 635
H+ +H ++ E RK ++
Sbjct: 614 LIRHLRTHTGEKPYECNECRKAFREK---------------------------------- 639
Query: 636 PKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
S N+ ++ ++P++C C +A+ + HL H R+HTGEKP+ CS+C + F
Sbjct: 640 ------SSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFS 693
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
L H R HTG K ++C+ C AF+ L H H
Sbjct: 694 QKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 261 bits (667), Expect = 4e-69
Identities = 176/551 (31%), Positives = 247/551 (44%), Gaps = 59/551 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C C +FP++SQF H R H +KP+ C QC + F+ + LT H+ TH+GE P C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHT-GEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGE 295
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FSR + L +H H E+ C+ECG F+ +S L H H G + C+
Sbjct: 296 CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIH----TGEKPFECRE 351
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F S+L H +TH + + C C K F + S+L RH
Sbjct: 352 CGKAFSRKSQLVTHHRTHTGTK----------------PFGCSDCRKAFFEKSELIRHQT 395
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
IHTGE+P++CSEC KAF ++ +L H HTGEKPH C C AFSQK +L SH Q H+
Sbjct: 396 IHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH-QMTHT 454
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
K + C++C F L H + H G S A + L L
Sbjct: 455 GEK---PFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKA------FSEKLSLTN 504
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ T S+ Q+ +S +G+ P + G
Sbjct: 505 HQRIHTGEKPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFG---------- 553
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
E S L A H T + D ++++ ++ E P +
Sbjct: 554 EKSSL-----ATHQ----RTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K +K L +R G + + C C K FR+ S L+ H RIHT EKPF+C +C +
Sbjct: 605 RKAFFEKSE--LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF-- 575
AF+ KS L H +THTG K + C C K+FS L H R+HTG +P+ C C K F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQ 722
Query: 576 --RTSGHRKTH 584
+ H++TH
Sbjct: 723 KSQLINHQRTH 733
Score = 236 bits (603), Expect = 1e-61
Identities = 182/627 (29%), Positives = 253/627 (40%), Gaps = 85/627 (13%)
Query: 160 KEFETSSELKEHMKTHYK--IRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTRHI 216
K +T + LK + YK + S Y+RN R G Y C C K F K L +H
Sbjct: 169 KPEDTDTWLKYYDCDKYKESYKKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQ 226
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
H + F C CGK F QK TH HTGEKP+ C+ C AFSQK L SH QR H
Sbjct: 227 SRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSH-QRTH 285
Query: 277 SEVKNGPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+ K Y C EC F L TH + G + + +E ++++ T
Sbjct: 286 TGEK---PYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHT 342
Query: 333 --LPLQQTEA-QATSASSQPSSQ----------AVSDVIQQLLELSE---PAPVESGQSP 376
P + E +A S SQ + SD + E SE + +G+ P
Sbjct: 343 GEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKP 402
Query: 377 QPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ 436
+ ++ H + H A + +S++
Sbjct: 403 YECSECRKAFRERSSLINHQ-----------RTHTGEKPHGCIQCGKAFSQKSHLISHQM 451
Query: 437 TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSD 496
T E P K K +K L R G + + C C K F +
Sbjct: 452 THTG--------EKPFICSKCGKAFSRKSQ--LVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 497 LVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVH 556
L H RIHT EKP+ C +C +AF KS L +H +THTG K ++C C K+F SL H
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561
Query: 557 IRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVP 616
R HTG +P+ C C+K F TH +++ KP + + +
Sbjct: 562 QRTHTGEKPYECRDCEKAFSQKSQLNTH----------QRIHTGEKPYECSLCRKAF--- 608
Query: 617 DIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHI 676
++ LI L + ++PY+C C +A+++ L H
Sbjct: 609 ---FEKSELIRHLR-------------------THTGEKPYECNECRKAFREKSSLINHQ 646
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
R HTGEKPF+CS+CG+ F L H RTHTG K + C C AF+ L H IH
Sbjct: 647 RIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT 706
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+PY C C K F H +TH
Sbjct: 707 GEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 213 bits (541), Expect = 2e-54
Identities = 152/593 (25%), Positives = 243/593 (40%), Gaps = 70/593 (11%)
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
+K KK + R + + C C K F + S + H R HT EKP+ C QC +A
Sbjct: 213 RKRFSKKPSLIKHQSRHIRDIAFG-CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKA 271
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F+ KS LT+H +THTG K ++C C K+FS L H R HTG +P+ C C + F
Sbjct: 272 FSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFS-- 329
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
K+++ +H +++ KP + R GK ++ L+T
Sbjct: 330 --EKSNLINH------QRIHTGEKPFECRECGKAFS-------RKSQLVT---------- 364
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
++ + +P+ C C +A+ + L +H HTGEKP++CS+C + F
Sbjct: 365 ---------HHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L H RTHTG K C+ C AF+ L H H +P++C C K F
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475
Query: 758 KHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPE 817
+H +TH E + + +A S S + Q + + V E +
Sbjct: 476 RHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK------------- 522
Query: 818 AMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877
+ H++ + G ++P E E G + + + + ++ +E
Sbjct: 523 --AFCQKSHLISHQRTHTG----EKPYECSECGKAFGE---KSSLATHQRTHTGEKPYEC 573
Query: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQ-DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTR 936
+ F+ Q+ Q Q++ E +F ++S L T
Sbjct: 574 RDCEKAFS------QKSQLNTHQRIHTGEKPYECSLCRKAFFEKSEL---IRHLRTHTGE 624
Query: 937 LIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
E ++ + + S + + C C K F + SHL H R+HTGEKPY
Sbjct: 625 KPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYG 684
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
C C + F L +H++ HTG K + C C +F+ L H TH K
Sbjct: 685 CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 205 bits (522), Expect = 3e-52
Identities = 111/317 (35%), Positives = 150/317 (47%), Gaps = 10/317 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F + SHL H R+HTGEKPY C CGR F L +H++ HTG K F
Sbjct: 289 KPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFE 348
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ L H TH KP+ C C + F K + RHQT+ +
Sbjct: 349 CRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFE----KSELIRHQTIHTGEKPYE 404
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+E E + + +P + +Q + + + EK + S
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1145 EK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K R S+L R ++ ++P C+ C K+F + L H RIHTGEKPY C ECG
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYE---CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS L H +THTG+K + C C AF K SL H R HTG KP++C CE F
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581
Query: 1262 TSGRRKTHMQFHYKPDP 1278
+ TH + H P
Sbjct: 582 QKSQLNTHQRIHTGEKP 598
Score = 201 bits (511), Expect = 5e-51
Identities = 107/332 (32%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C + F + S+L H R HTGEKP++C+ CG+ F L +H +THTG K F
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F L RH H KPY+C C + FR + + HQ + G
Sbjct: 377 CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRE----RSSLINHQRTHTGEKPHG 432
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ G ++ S + +P + + + ++ +++ + EK S
Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492
Query: 1145 EK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K +++S ++ ++P C+ C K+F + S L+ H R HTGEKPY+C ECG
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPY---VCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS+L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFF 609
Query: 1262 TSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
H++ H P + RK SS
Sbjct: 610 EKSELIRHLRTHTGEKPYECNECRKAFREKSS 641
Score = 199 bits (507), Expect = 2e-50
Identities = 106/313 (33%), Positives = 152/313 (48%), Gaps = 12/313 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F + SHL H +HTGEKP+ C CG+ F L H++THTG K +
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
CS C +F+ SLT H H KPY C C + F H H + H P S
Sbjct: 489 CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ G E+ + + +P E+ +Q +++ + EK S
Sbjct: 549 GKAFG-----EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603
Query: 1144 AEK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K ++ +R + ++P C C K+F++ S L+ H RIHTGEKP++C EC
Sbjct: 604 CRKAFFEKSELIRHLRTHTGEKPYE---CNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ KS L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720
Query: 1261 RTSGRRKTHMQFH 1273
+ H + H
Sbjct: 721 SQKSQLINHQRTH 733
Score = 199 bits (505), Expect = 3e-50
Identities = 110/321 (34%), Positives = 152/321 (47%), Gaps = 18/321 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F++ S L H R+HTGEKP+ C CG+ F L SH+ THTG K F
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F+ L RH TH KPY+C C + F + H + H TG
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIH---------TG 511
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E +E G ++ S + +P + + + + + + EK
Sbjct: 512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPY 571
Query: 1140 VQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
EK + S+L Q E + C+ C K+F + S+L+RH+R HTGEKPY+C
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYE--CSLCRKAFFEKSELIRHLRTHTGEKPYEC 629
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+EC K+F KS+L H + HTG+K F C C AFS K L H R HTG KP+ C C
Sbjct: 630 NECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECR 689
Query: 1258 LRFRTSGRRKTHMQFHYKPDP 1278
F + H + H P
Sbjct: 690 KAFSQKSQLVNHQRIHTGEKP 710
Score = 184 bits (468), Expect = 5e-46
Identities = 141/509 (27%), Positives = 210/509 (41%), Gaps = 71/509 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F ++SQ H R H +KP+ C +C + F+ + +L H TH+GE P C
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGC 321
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------------ 143
C + FS ++L H +H E+ C ECG F+ +SQL H H
Sbjct: 322 NECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCR 381
Query: 144 -----RQEL-------AGTRQHACKACKKEFETSSELKEHMKTHYK------IRVSSTRS 185
+ EL G + + C C+K F S L H +TH I+ S
Sbjct: 382 KAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFS 441
Query: 186 YNRNIDRSGFTYS------CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
++ T++ C CGK F + SQL RH R HTGE+P++CSECGKAF++K +
Sbjct: 442 QKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGS 299
L H HTGEKP+ C+ C AF QK +L SH QR H+ K Y C+EC F S
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK---PYECSECGKAFGEKSS 557
Query: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359
L TH + H G E A + L + E + + + S++I+
Sbjct: 558 LATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIR 616
Query: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419
L + P E + + ++ S ++ ++G +
Sbjct: 617 HLRTHTGEKPYECNECRKAFREKS-------SLINHQRIHTGEKPFECSECGKAFSRKSH 669
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
PH ++ E P + K +K L R G
Sbjct: 670 LIPH-------------------QRTHTGEKPYGCSECRKAFSQKSQ--LVNHQRIHTGE 708
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
+ + C C K F + S L+ H R HT +K
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 180 bits (457), Expect = 1e-44
Identities = 140/574 (24%), Positives = 220/574 (38%), Gaps = 61/574 (10%)
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
+ C + +++ + + H GEK + C+ C FS+K +L H R ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI----A 234
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F TH + H G + S A + L T Q T
Sbjct: 235 FGCGNCGKTFPQKSQFITH-HRTHTGEKPYNCSQCGKAFSQKSQL--------TSHQRTH 285
Query: 345 ASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLS 403
+P + L +G+ P + +++ ++G
Sbjct: 286 TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345
Query: 404 SIPAAAHPNDSCHAKTSAPHAQN---------PDVSSVSNEQTDPTDAEQEKEQESPEKL 454
H + D E+++ + E P +
Sbjct: 346 PFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K ++ S L R G + H C C K F + S L+ H HT EKPF C +
Sbjct: 406 SECRKAFRERSS--LINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSK 463
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L H +THTG K ++C C K+FS SL H R+HTG +P+ C C K
Sbjct: 464 CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
F +K+H+ SH + T + ++ G+ +
Sbjct: 524 FC----QKSHLISH-QRTHTGEKPYECSECGKAFGEKS---------------------- 556
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF 694
S + + ++PY+C C +A+ + L H R HTGEKP++CS C + F
Sbjct: 557 --------SLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608
Query: 695 VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSL 754
L H+RTHTG K ++C C AF SL H IH +P+ C C K F
Sbjct: 609 FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKS 668
Query: 755 NCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
+ H +TH E + ++A S V+ Q
Sbjct: 669 HLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQ 702
Score = 170 bits (431), Expect = 1e-41
Identities = 96/315 (30%), Positives = 139/315 (44%), Gaps = 10/315 (3%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y C C K F K L +H H + + C CG+ F +H +THTG K ++CS
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCS 266
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ LT H TH KPY+C C + F H H + H + G
Sbjct: 267 QCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEKPYGCN 322
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
E G E+ + + +P + ++ +++ K S K
Sbjct: 323 ECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRK 382
Query: 1147 ---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
++ +R + ++P C+ C K+F++ S L+ H R HTGEKP+ C +CGK+
Sbjct: 383 AFFEKSELIRHQTIHTGEKPYE---CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ KS L H THTG+K F C C AFS K L H R HTG KP++C C F
Sbjct: 440 FSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEK 499
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 500 LSLTNHQRIHTGEKP 514
Score = 128 bits (322), Expect = 4e-29
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L++H + H E+ HGC C KAF + +HL H TH
Sbjct: 401 KPYECSECRKAFRERSSLINHQR-THTGEKPHGCIQCGKAFSQKSHLISHQMTH------ 453
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F C C KAF++ SQL RH R HTGE+P+ C+ C KAF++K +L H + HTG
Sbjct: 454 TGEKP--FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C+ C F QKS++ H +R H+
Sbjct: 512 EKPYVCSECGKAFCQKSHLISH-QRTHT 538
Score = 127 bits (320), Expect = 8e-29
Identities = 62/160 (38%), Positives = 95/160 (59%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G +LA + + ++C +C++AFS + L H + +H E+ + C +CRKAF
Sbjct: 553 GEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-IHTGEKPYECSLCRKAFFEK 611
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L H++TH + +KP ++C+ C KAF + S L H RIHTGE+PF C+ C KA
Sbjct: 612 SELIRHLRTH------TGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKA 663
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F++KS L H + HTGE+PY C+ C F+QKS + H +
Sbjct: 664 FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQR 703
Score = 123 bits (309), Expect = 1e-27
Identities = 67/173 (38%), Positives = 98/173 (56%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + L+ H + H E+ + C C KAF + L H +TH
Sbjct: 513 KPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFGEKSSLATHQRTH------ 565
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF++ SQL H RIHTGE+P+ C+LC KAF +KS L H++ HTG
Sbjct: 566 TGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTG 623
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+PY+C C F +KS++ H +R H+ E + G+ SR HL
Sbjct: 624 EKPYECNECRKAFREKSSLINH-QRIHT-----GEKPFECSECGKAFSRKSHL 670
Score = 118 bits (295), Expect = 6e-26
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC RAFS + L++H + +H E+ C C KAF R + L H +TH
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQR-IHTGEKPFECRECGKAFSRKSQLVTHHRTH------ 369
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP F C C KAF + S+L RH IHTGE+P+ C+ C KAF ++S+L H + HTG
Sbjct: 370 TGTKP--FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTG 427
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+P+ C C F+QKS++ H
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISH 449
Score = 112 bits (280), Expect = 3e-24
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L+ H + H E+ +GC C +AF ++L H + H
Sbjct: 289 KPYECGECGKAFSRKSHLISHWR-THTGEKPYGCNECGRAFSEKSNLINHQRIH------ 341
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F+C C KAF++ SQL H R HTG +PF C+ C KAF +KS L H HTG
Sbjct: 342 TGEKP--FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTG 399
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C F ++S++ H +R H+
Sbjct: 400 EKPYECSECRKAFRERSSLINH-QRTHT 426
Score = 112 bits (279), Expect = 4e-24
Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS L+ H H R+ GC C K F + + H +TH
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSR-HIRDIAFGCGNCGKTFPQKSQFITHHRTH------ 257
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAF++ SQL H R HTGE+P+ C C KAF++KS L H + HTG
Sbjct: 258 TGEKP--YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTG 315
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F++KSN+ H +
Sbjct: 316 EKPYGCNECGRAFSEKSNLINHQR 339
Score = 108 bits (271), Expect = 4e-23
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S + H R HTGEKPY C +CGK+F+ KS L H +THTG+K + C C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AFS K L H R HTG KP+ C C F H + H P + R+
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351
Score = 103 bits (256), Expect = 2e-21
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 13/154 (8%)
Query: 1648 NQPEKEGRAHQCLECDR---AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEH 1704
++PE + +CD+ ++ + ++++H + E+++ C CRK F + L +H
Sbjct: 168 SKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLG--EKLYECSECRKRFSKKPSLIKH 225
Query: 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSA 1764
H + F C C K F + SQ H R HTGE+P++C+ C KAF+QKS
Sbjct: 226 QSRHI--------RDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQ 277
Query: 1765 LQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
L H + HTGE+PY+C C F++KS++ H +
Sbjct: 278 LTSHQRTHTGEKPYECGECGKAFSRKSHLISHWR 311
Score = 73.6 bits (179), Expect = 2e-12
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
L K + K+ +C Y +S+KK ++ H R GEK Y+C EC K F+ K +L
Sbjct: 166 LHSKPEDTDTWLKYYDCDKY-KESYKKSQIIIYH-RNRLGEKLYECSECRKRFSKKPSLI 223
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H H F C C F K H R HTG KP+ C C F + +H +
Sbjct: 224 KHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQR 283
Query: 1272 FHYKPDP 1278
H P
Sbjct: 284 THTGEKP 290
Score = 62.0 bits (149), Expect = 5e-09
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y C C K F + S L H R HTGEKPY+C CG+ F L +H++THT K+
Sbjct: 681 KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKKS 738
>gi|188497653 zinc finger protein 84 [Homo sapiens]
Length = 738
Score = 267 bits (683), Expect = 6e-71
Identities = 178/640 (27%), Positives = 273/640 (42%), Gaps = 110/640 (17%)
Query: 109 KAHIMLHEK----EENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFET 164
K+ I+++ + E+ CSEC F+ + L H H +++A C C K F
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIA----FGCGNCGKTFPQ 246
Query: 165 SSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERP 224
S+ H +TH + + YN C CGK F + SQLT H R HTGE+P
Sbjct: 247 KSQFITHHRTH-----TGEKPYN-----------CSQCGKAFSQKSQLTSHQRTHTGEKP 290
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
++C ECGKAF++K L +H HTGEKP+ C C AFS+K NL +H QR+H+ K
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEK---P 346
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C EC F L TH + H G S A + L + + E
Sbjct: 347 FECRECGKAFSRKSQLVTH-HRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
+ + + + S +I +G+ P Q ++ + ++G
Sbjct: 406 SECRKAFRERSSLINH-------QRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTG--- 455
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSS----VSNEQTDPTDAEQEKEQESPEKLDKKEKK 460
+ P + S + ++ ++ E P + + K
Sbjct: 456 --------------------EKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKA 495
Query: 461 MIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFA 520
+K S L R G + +VC C K F + S L+ H R HT EKP++C +C +AF
Sbjct: 496 FSEKLS--LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFG 553
Query: 521 VKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGH 580
KS+L H +THTG K ++C+ C K+FS L H R+HTG +P+ C C K F
Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE 613
Query: 581 RKTHIASH-----FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPI 635
H+ +H ++ E RK ++
Sbjct: 614 LIRHLRTHTGEKPYECNECRKAFREK---------------------------------- 639
Query: 636 PKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
S N+ ++ ++P++C C +A+ + HL H R+HTGEKP+ CS+C + F
Sbjct: 640 ------SSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFS 693
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
L H R HTG K ++C+ C AF+ L H H
Sbjct: 694 QKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 261 bits (667), Expect = 4e-69
Identities = 176/551 (31%), Positives = 247/551 (44%), Gaps = 59/551 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C C +FP++SQF H R H +KP+ C QC + F+ + LT H+ TH+GE P C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHT-GEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGE 295
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FSR + L +H H E+ C+ECG F+ +S L H H G + C+
Sbjct: 296 CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIH----TGEKPFECRE 351
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F S+L H +TH + + C C K F + S+L RH
Sbjct: 352 CGKAFSRKSQLVTHHRTHTGTK----------------PFGCSDCRKAFFEKSELIRHQT 395
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
IHTGE+P++CSEC KAF ++ +L H HTGEKPH C C AFSQK +L SH Q H+
Sbjct: 396 IHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH-QMTHT 454
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
K + C++C F L H + H G S A + L L
Sbjct: 455 GEK---PFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKA------FSEKLSLTN 504
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ T S+ Q+ +S +G+ P + G
Sbjct: 505 HQRIHTGEKPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFG---------- 553
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
E S L A H T + D ++++ ++ E P +
Sbjct: 554 EKSSL-----ATHQ----RTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K +K L +R G + + C C K FR+ S L+ H RIHT EKPF+C +C +
Sbjct: 605 RKAFFEKSE--LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF-- 575
AF+ KS L H +THTG K + C C K+FS L H R+HTG +P+ C C K F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQ 722
Query: 576 --RTSGHRKTH 584
+ H++TH
Sbjct: 723 KSQLINHQRTH 733
Score = 236 bits (603), Expect = 1e-61
Identities = 182/627 (29%), Positives = 253/627 (40%), Gaps = 85/627 (13%)
Query: 160 KEFETSSELKEHMKTHYK--IRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTRHI 216
K +T + LK + YK + S Y+RN R G Y C C K F K L +H
Sbjct: 169 KPEDTDTWLKYYDCDKYKESYKKSQIIIYHRN--RLGEKLYECSECRKRFSKKPSLIKHQ 226
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
H + F C CGK F QK TH HTGEKP+ C+ C AFSQK L SH QR H
Sbjct: 227 SRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSH-QRTH 285
Query: 277 SEVKNGPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+ K Y C EC F L TH + G + + +E ++++ T
Sbjct: 286 TGEK---PYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHT 342
Query: 333 --LPLQQTEA-QATSASSQPSSQ----------AVSDVIQQLLELSE---PAPVESGQSP 376
P + E +A S SQ + SD + E SE + +G+ P
Sbjct: 343 GEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKP 402
Query: 377 QPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ 436
+ ++ H + H A + +S++
Sbjct: 403 YECSECRKAFRERSSLINHQ-----------RTHTGEKPHGCIQCGKAFSQKSHLISHQM 451
Query: 437 TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSD 496
T E P K K +K L R G + + C C K F +
Sbjct: 452 THTG--------EKPFICSKCGKAFSRKSQ--LVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 497 LVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVH 556
L H RIHT EKP+ C +C +AF KS L +H +THTG K ++C C K+F SL H
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561
Query: 557 IRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVP 616
R HTG +P+ C C+K F TH +++ KP + + +
Sbjct: 562 QRTHTGEKPYECRDCEKAFSQKSQLNTH----------QRIHTGEKPYECSLCRKAF--- 608
Query: 617 DIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHI 676
++ LI L + ++PY+C C +A+++ L H
Sbjct: 609 ---FEKSELIRHLR-------------------THTGEKPYECNECRKAFREKSSLINHQ 646
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
R HTGEKPF+CS+CG+ F L H RTHTG K + C C AF+ L H IH
Sbjct: 647 RIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT 706
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+PY C C K F H +TH
Sbjct: 707 GEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 213 bits (541), Expect = 2e-54
Identities = 152/593 (25%), Positives = 243/593 (40%), Gaps = 70/593 (11%)
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
+K KK + R + + C C K F + S + H R HT EKP+ C QC +A
Sbjct: 213 RKRFSKKPSLIKHQSRHIRDIAFG-CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKA 271
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F+ KS LT+H +THTG K ++C C K+FS L H R HTG +P+ C C + F
Sbjct: 272 FSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFS-- 329
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
K+++ +H +++ KP + R GK ++ L+T
Sbjct: 330 --EKSNLINH------QRIHTGEKPFECRECGKAFS-------RKSQLVT---------- 364
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
++ + +P+ C C +A+ + L +H HTGEKP++CS+C + F
Sbjct: 365 ---------HHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L H RTHTG K C+ C AF+ L H H +P++C C K F
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475
Query: 758 KHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPE 817
+H +TH E + + +A S S + Q + + V E +
Sbjct: 476 RHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK------------- 522
Query: 818 AMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877
+ H++ + G ++P E E G + + + + ++ +E
Sbjct: 523 --AFCQKSHLISHQRTHTG----EKPYECSECGKAFGE---KSSLATHQRTHTGEKPYEC 573
Query: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQ-DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTR 936
+ F+ Q+ Q Q++ E +F ++S L T
Sbjct: 574 RDCEKAFS------QKSQLNTHQRIHTGEKPYECSLCRKAFFEKSEL---IRHLRTHTGE 624
Query: 937 LIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
E ++ + + S + + C C K F + SHL H R+HTGEKPY
Sbjct: 625 KPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYG 684
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
C C + F L +H++ HTG K + C C +F+ L H TH K
Sbjct: 685 CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 205 bits (522), Expect = 3e-52
Identities = 111/317 (35%), Positives = 150/317 (47%), Gaps = 10/317 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F + SHL H R+HTGEKPY C CGR F L +H++ HTG K F
Sbjct: 289 KPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFE 348
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F+ L H TH KP+ C C + F K + RHQT+ +
Sbjct: 349 CRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFE----KSELIRHQTIHTGEKPYE 404
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+E E + + +P + +Q + + + EK + S
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1145 EK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K R S+L R ++ ++P C+ C K+F + L H RIHTGEKPY C ECG
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYE---CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS L H +THTG+K + C C AF K SL H R HTG KP++C CE F
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581
Query: 1262 TSGRRKTHMQFHYKPDP 1278
+ TH + H P
Sbjct: 582 QKSQLNTHQRIHTGEKP 598
Score = 201 bits (511), Expect = 5e-51
Identities = 107/332 (32%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C + F + S+L H R HTGEKP++C+ CG+ F L +H +THTG K F
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG 376
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F L RH H KPY+C C + FR + + HQ + G
Sbjct: 377 CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRE----RSSLINHQRTHTGEKPHG 432
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ G ++ S + +P + + + ++ +++ + EK S
Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492
Query: 1145 EK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
K +++S ++ ++P C+ C K+F + S L+ H R HTGEKPY+C ECG
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPY---VCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F KS+L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFF 609
Query: 1262 TSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
H++ H P + RK SS
Sbjct: 610 EKSELIRHLRTHTGEKPYECNECRKAFREKSS 641
Score = 199 bits (507), Expect = 2e-50
Identities = 106/313 (33%), Positives = 152/313 (48%), Gaps = 12/313 (3%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F + SHL H +HTGEKP+ C CG+ F L H++THTG K +
Sbjct: 429 KPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
CS C +F+ SLT H H KPY C C + F H H + H P S
Sbjct: 489 CSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ G E+ + + +P E+ +Q +++ + EK S
Sbjct: 549 GKAFG-----EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603
Query: 1144 AEK---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K ++ +R + ++P C C K+F++ S L+ H RIHTGEKP++C EC
Sbjct: 604 CRKAFFEKSELIRHLRTHTGEKPYE---CNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ KS L H +THTG+K + C C AFS K L H R+HTG KP++C C F
Sbjct: 661 GKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAF 720
Query: 1261 RTSGRRKTHMQFH 1273
+ H + H
Sbjct: 721 SQKSQLINHQRTH 733
Score = 199 bits (505), Expect = 3e-50
Identities = 110/321 (34%), Positives = 152/321 (47%), Gaps = 18/321 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F++ S L H R+HTGEKP+ C CG+ F L SH+ THTG K F
Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
CS C +F+ L RH TH KPY+C C + F + H + H TG
Sbjct: 461 CSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIH---------TG 511
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E +E G ++ S + +P + + + + + + EK
Sbjct: 512 EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPY 571
Query: 1140 VQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
EK + S+L Q E + C+ C K+F + S+L+RH+R HTGEKPY+C
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYE--CSLCRKAFFEKSELIRHLRTHTGEKPYEC 629
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+EC K+F KS+L H + HTG+K F C C AFS K L H R HTG KP+ C C
Sbjct: 630 NECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECR 689
Query: 1258 LRFRTSGRRKTHMQFHYKPDP 1278
F + H + H P
Sbjct: 690 KAFSQKSQLVNHQRIHTGEKP 710
Score = 184 bits (468), Expect = 5e-46
Identities = 141/509 (27%), Positives = 210/509 (41%), Gaps = 71/509 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F ++SQ H R H +KP+ C +C + F+ + +L H TH+GE P C
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGC 321
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEH------------ 143
C + FS ++L H +H E+ C ECG F+ +SQL H H
Sbjct: 322 NECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCR 381
Query: 144 -----RQEL-------AGTRQHACKACKKEFETSSELKEHMKTHYK------IRVSSTRS 185
+ EL G + + C C+K F S L H +TH I+ S
Sbjct: 382 KAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFS 441
Query: 186 YNRNIDRSGFTYS------CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
++ T++ C CGK F + SQL RH R HTGE+P++CSECGKAF++K +
Sbjct: 442 QKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS 501
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGS 299
L H HTGEKP+ C+ C AF QK +L SH QR H+ K Y C+EC F S
Sbjct: 502 LTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK---PYECSECGKAFGEKSS 557
Query: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359
L TH + H G E A + L + E + + + S++I+
Sbjct: 558 LATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIR 616
Query: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419
L + P E + + ++ S ++ ++G +
Sbjct: 617 HLRTHTGEKPYECNECRKAFREKS-------SLINHQRIHTGEKPFECSECGKAFSRKSH 669
Query: 420 SAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGV 479
PH ++ E P + K +K L R G
Sbjct: 670 LIPH-------------------QRTHTGEKPYGCSECRKAFSQKSQ--LVNHQRIHTGE 708
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
+ + C C K F + S L+ H R HT +K
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 180 bits (457), Expect = 1e-44
Identities = 140/574 (24%), Positives = 220/574 (38%), Gaps = 61/574 (10%)
Query: 225 FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
+ C + +++ + + H GEK + C+ C FS+K +L H R ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDI----A 234
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F TH + H G + S A + L T Q T
Sbjct: 235 FGCGNCGKTFPQKSQFITH-HRTHTGEKPYNCSQCGKAFSQKSQL--------TSHQRTH 285
Query: 345 ASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLS 403
+P + L +G+ P + +++ ++G
Sbjct: 286 TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345
Query: 404 SIPAAAHPNDSCHAKTSAPHAQN---------PDVSSVSNEQTDPTDAEQEKEQESPEKL 454
H + D E+++ + E P +
Sbjct: 346 PFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYEC 405
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K ++ S L R G + H C C K F + S L+ H HT EKPF C +
Sbjct: 406 SECRKAFRERSS--LINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSK 463
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L H +THTG K ++C C K+FS SL H R+HTG +P+ C C K
Sbjct: 464 CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQP 634
F +K+H+ SH + T + ++ G+ +
Sbjct: 524 FC----QKSHLISH-QRTHTGEKPYECSECGKAFGEKS---------------------- 556
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF 694
S + + ++PY+C C +A+ + L H R HTGEKP++CS C + F
Sbjct: 557 --------SLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608
Query: 695 VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSL 754
L H+RTHTG K ++C C AF SL H IH +P+ C C K F
Sbjct: 609 FEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKS 668
Query: 755 NCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
+ H +TH E + ++A S V+ Q
Sbjct: 669 HLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQ 702
Score = 170 bits (431), Expect = 1e-41
Identities = 96/315 (30%), Positives = 139/315 (44%), Gaps = 10/315 (3%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y C C K F K L +H H + + C CG+ F +H +THTG K ++CS
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCS 266
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F+ LT H TH KPY+C C + F H H + H + G
Sbjct: 267 QCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEKPYGCN 322
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
E G E+ + + +P + ++ +++ K S K
Sbjct: 323 ECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRK 382
Query: 1147 ---DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
++ +R + ++P C+ C K+F++ S L+ H R HTGEKP+ C +CGK+
Sbjct: 383 AFFEKSELIRHQTIHTGEKPYE---CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ KS L H THTG+K F C C AFS K L H R HTG KP++C C F
Sbjct: 440 FSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEK 499
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 500 LSLTNHQRIHTGEKP 514
Score = 128 bits (322), Expect = 4e-29
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L++H + H E+ HGC C KAF + +HL H TH
Sbjct: 401 KPYECSECRKAFRERSSLINHQR-THTGEKPHGCIQCGKAFSQKSHLISHQMTH------ 453
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F C C KAF++ SQL RH R HTGE+P+ C+ C KAF++K +L H + HTG
Sbjct: 454 TGEKP--FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG 511
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C+ C F QKS++ H +R H+
Sbjct: 512 EKPYVCSECGKAFCQKSHLISH-QRTHT 538
Score = 127 bits (320), Expect = 8e-29
Identities = 62/160 (38%), Positives = 95/160 (59%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G +LA + + ++C +C++AFS + L H + +H E+ + C +CRKAF
Sbjct: 553 GEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-IHTGEKPYECSLCRKAFFEK 611
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L H++TH + +KP ++C+ C KAF + S L H RIHTGE+PF C+ C KA
Sbjct: 612 SELIRHLRTH------TGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKA 663
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F++KS L H + HTGE+PY C+ C F+QKS + H +
Sbjct: 664 FSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQR 703
Score = 123 bits (309), Expect = 1e-27
Identities = 67/173 (38%), Positives = 98/173 (56%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + L+ H + H E+ + C C KAF + L H +TH
Sbjct: 513 KPYVCSECGKAFCQKSHLISHQR-THTGEKPYECSECGKAFGEKSSLATHQRTH------ 565
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF++ SQL H RIHTGE+P+ C+LC KAF +KS L H++ HTG
Sbjct: 566 TGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTG 623
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+PY+C C F +KS++ H +R H+ E + G+ SR HL
Sbjct: 624 EKPYECNECRKAFREKSSLINH-QRIHT-----GEKPFECSECGKAFSRKSHL 670
Score = 118 bits (295), Expect = 6e-26
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC RAFS + L++H + +H E+ C C KAF R + L H +TH
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQR-IHTGEKPFECRECGKAFSRKSQLVTHHRTH------ 369
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP F C C KAF + S+L RH IHTGE+P+ C+ C KAF ++S+L H + HTG
Sbjct: 370 TGTKP--FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTG 427
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+P+ C C F+QKS++ H
Sbjct: 428 EKPHGCIQCGKAFSQKSHLISH 449
Score = 112 bits (280), Expect = 3e-24
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L+ H + H E+ +GC C +AF ++L H + H
Sbjct: 289 KPYECGECGKAFSRKSHLISHWR-THTGEKPYGCNECGRAFSEKSNLINHQRIH------ 341
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP F+C C KAF++ SQL H R HTG +PF C+ C KAF +KS L H HTG
Sbjct: 342 TGEKP--FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTG 399
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C F ++S++ H +R H+
Sbjct: 400 EKPYECSECRKAFRERSSLINH-QRTHT 426
Score = 112 bits (279), Expect = 4e-24
Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS L+ H H R+ GC C K F + + H +TH
Sbjct: 205 KLYECSECRKRFSKKPSLIKHQSR-HIRDIAFGCGNCGKTFPQKSQFITHHRTH------ 257
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAF++ SQL H R HTGE+P+ C C KAF++KS L H + HTG
Sbjct: 258 TGEKP--YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTG 315
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F++KSN+ H +
Sbjct: 316 EKPYGCNECGRAFSEKSNLINHQR 339
Score = 108 bits (271), Expect = 4e-23
Identities = 49/115 (42%), Positives = 62/115 (53%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K+F + S + H R HTGEKPY C +CGK+F+ KS L H +THTG+K + C C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
AFS K L H R HTG KP+ C C F H + H P + R+
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351
Score = 103 bits (256), Expect = 2e-21
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 13/154 (8%)
Query: 1648 NQPEKEGRAHQCLECDR---AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEH 1704
++PE + +CD+ ++ + ++++H + E+++ C CRK F + L +H
Sbjct: 168 SKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLG--EKLYECSECRKRFSKKPSLIKH 225
Query: 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSA 1764
H + F C C K F + SQ H R HTGE+P++C+ C KAF+QKS
Sbjct: 226 QSRHI--------RDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQ 277
Query: 1765 LQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
L H + HTGE+PY+C C F++KS++ H +
Sbjct: 278 LTSHQRTHTGEKPYECGECGKAFSRKSHLISHWR 311
Score = 73.6 bits (179), Expect = 2e-12
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
L K + K+ +C Y +S+KK ++ H R GEK Y+C EC K F+ K +L
Sbjct: 166 LHSKPEDTDTWLKYYDCDKY-KESYKKSQIIIYH-RNRLGEKLYECSECRKRFSKKPSLI 223
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H H F C C F K H R HTG KP+ C C F + +H +
Sbjct: 224 KHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQR 283
Query: 1272 FHYKPDP 1278
H P
Sbjct: 284 THTGEKP 290
Score = 62.0 bits (149), Expect = 5e-09
Identities = 26/58 (44%), Positives = 34/58 (58%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y C C K F + S L H R HTGEKPY+C CG+ F L +H++THT K+
Sbjct: 681 KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKKS 738
>gi|68303809 zinc finger protein 43 [Homo sapiens]
Length = 809
Score = 261 bits (667), Expect = 4e-69
Identities = 188/683 (27%), Positives = 284/683 (41%), Gaps = 88/683 (12%)
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K F + ++ H + H +++ C ECG F + LA H H TR + CK
Sbjct: 151 CVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIH------TRVNFCKC 204
Query: 158 --CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F S + +H + I+ Y+C CGK F S+LT H
Sbjct: 205 EKCGKAFNCPSIITKH----------------KRINTGEKPYTCEECGKVFNWSSRLTTH 248
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
+ +T + +KC ECGKAFN+ L TH I TGEK + C C AF+Q NL H +++
Sbjct: 249 KKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEH-KKI 307
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
H K Y C EC F +L H ++H G + A F
Sbjct: 308 HPGEK---PYKCEECGKAFNWPSTLTKH-KRIHTGEKPYTCEECGKA-------FNQFSN 356
Query: 336 QQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQ 395
T + +A + + L++ + + + P ++ + + +
Sbjct: 357 LTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEH 416
Query: 396 ALENSG-----------LSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQ 444
L ++G + P+ ++ H T + N+ ++ T ++
Sbjct: 417 KLTHTGEKPYKCEECGKAFNWPSTLTKHNRIH--TGEKPYKCEVCGKAFNQFSNLTTHKR 474
Query: 445 EKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIH 504
E P K ++ K + + I E + + C C K F+ S L H H
Sbjct: 475 IHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEK--KPYKCEECGKAFKWSSKLTEHKITH 532
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVR 564
T EKP+KC +C +AF S LT H + HTG K +KC+ C K+F+ S +L H ++HTG +
Sbjct: 533 TGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEK 592
Query: 565 PFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEP 623
+ C C K F S + TH +K+ KP K GK
Sbjct: 593 FYKCEECGKAFTQSSNLTTH----------KKIHTGGKPYKCEECGKA------------ 630
Query: 624 ILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
NQ F + + ++ ++PYKC C +A+K S L +H HTGEK
Sbjct: 631 -------------FNQ-FSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEK 676
Query: 684 PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMC 743
P+KC +CG+ F + L H HTG K +KC C AF +L H IH +PY C
Sbjct: 677 PYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKC 736
Query: 744 PYCQKTFKTSLNCKKHMKTHRYE 766
C K F S + H + H E
Sbjct: 737 EECGKAFNYSSHLNTHKRIHTKE 759
Score = 246 bits (627), Expect = 2e-64
Identities = 169/563 (30%), Positives = 242/563 (42%), Gaps = 47/563 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F K S H + +K ++C +C + FN NLT HK H GE P C
Sbjct: 258 YKCEECGKAFNKSSILTTH-KIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKC 316
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+ ++L H +H E+ C ECG F S L H H E + + C
Sbjct: 317 EECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAE----KFYKC 372
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C + F SS L +H K H + + Y C CGK F+ S+LT H
Sbjct: 373 TECGEAFSRSSNLTKHKKIHTEKK----------------PYKCEECGKAFKWSSKLTEH 416
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
HTGE+P+KC ECGKAFN L H HTGEKP+ C C AF+Q NL +H +R+
Sbjct: 417 KLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTH-KRI 475
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
H+ K Y C EC F +L H K+H+ A ++ L
Sbjct: 476 HTAEK---PYKCEECGKAFSRSSNLTKH-KKIHIEKKPYKCEECGKAFKWSSKL------ 525
Query: 336 QQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
TE + T +P + L++ + +G+ P ++ + ++
Sbjct: 526 --TEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTT 583
Query: 395 QALENSGLSSIPA-------AAHPNDSCHAK--TSAPHAQNPDVSSVSNEQTDPTDAEQE 445
++G N + H K T + + N+ + T +
Sbjct: 584 HKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKII 643
Query: 446 KEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 505
+E P K ++ K K S L G + + C C K F+ S L H IHT
Sbjct: 644 HTEEKPYKCEECGKAF--KWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHT 701
Query: 506 HEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRP 565
EKP+KC +C +AF S L H K HTG + +KC+ C K+F+ S L H R+HT +P
Sbjct: 702 GEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQP 761
Query: 566 FACPHCDKKFRTSGHRKTHIASH 588
+ C C K F + TH H
Sbjct: 762 YKCKECGKAFNQYSNLTTHNKIH 784
Score = 243 bits (620), Expect = 1e-63
Identities = 174/602 (28%), Positives = 255/602 (42%), Gaps = 89/602 (14%)
Query: 35 NFHKCEICLLSFPKESQFQRHMR------------------------DHERN---DKPHR 67
NF KCE C +F S +H R H++N K ++
Sbjct: 200 NFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYK 259
Query: 68 CDQCPQTFNVEFNLTLHKCTHSGED-PTCPVCNKKFSRVASLKAHIMLHEKEENLICSEC 126
C++C + FN LT HK +GE C C K F++ ++L H +H E+ C EC
Sbjct: 260 CEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEEC 319
Query: 127 GDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YK---- 177
G F S L H H G + + C+ C K F S L H + H YK
Sbjct: 320 GKAFNWPSTLTKHKRIH----TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTEC 375
Query: 178 ---IRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAF 234
SS + ++ I Y C CGK F+ S+LT H HTGE+P+KC ECGKAF
Sbjct: 376 GEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAF 435
Query: 235 NQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVF 294
N L H HTGEKP+ C C AF+Q NL +H +R+H+ K Y C EC F
Sbjct: 436 NWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTH-KRIHTAEK---PYKCEECGKAF 491
Query: 295 KSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQA 353
+L H K+H+ A ++ L TE + T +P +
Sbjct: 492 SRSSNLTKH-KKIHIEKKPYKCEECGKAFKWSSKL--------TEHKITHTGEKPYKCEE 542
Query: 354 VSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPND 413
L++ + +G+ P ++ +A S + H +
Sbjct: 543 CGKAFNHFSILTKHKRIHTGEKPYKCEECG-----------KAFTQSSNLTTHKKIHTGE 591
Query: 414 SCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDK-----KEKKMIKKKSPF 468
+ A S+++ + T + K +E + ++ K K + ++ P+
Sbjct: 592 KFYKCEECGKAFTQS-SNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPY 650
Query: 469 LPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAH 528
C C K F+ S L +H IHT EKP+KC +C +AF + STL+ H
Sbjct: 651 --------------KCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTH 696
Query: 529 IKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
HTG K +KC+ C K+F+ S +L H ++HTG +P+ C C K F S H TH H
Sbjct: 697 KIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIH 756
Query: 589 FK 590
K
Sbjct: 757 TK 758
Score = 218 bits (555), Expect = 4e-56
Identities = 152/541 (28%), Positives = 230/541 (42%), Gaps = 71/541 (13%)
Query: 36 FHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-T 94
F+KC+ C +F + S H + H +KP++C++C + FN LT HK H+GE P T
Sbjct: 285 FYKCKECAKAFNQSSNLTEHKKIHP-GEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYT 343
Query: 95 CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVH--------------- 139
C C K F++ ++L H +H E+ C+ECG+ F+ S L H
Sbjct: 344 CEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEEC 403
Query: 140 ---------MEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YKIRVS---- 181
+ EH+ G + + C+ C K F S L +H + H YK V
Sbjct: 404 GKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAF 463
Query: 182 ---STRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKG 238
S + ++ I + Y C CGK F + S LT+H +IH ++P+KC ECGKAF
Sbjct: 464 NQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSS 523
Query: 239 ALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLG 298
L H I HTGEKP+ C C AF+ L H +R+H+ K Y C EC F
Sbjct: 524 KLTEHKITHTGEKPYKCEECGKAFNHFSILTKH-KRIHTGEK---PYKCEECGKAFTQSS 579
Query: 299 SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVI 358
+L TH K+H G A ++ L T + + +
Sbjct: 580 NLTTH-KKIHTGEKFYKCEECGKAFTQSSNL-------TTHKKIHTGGKPYKCEECGKAF 631
Query: 359 QQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAK 418
Q L++ + + + P ++ + + + + ++G + + C
Sbjct: 632 NQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTG-----EKPYKCEECGKA 686
Query: 419 TSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENG 478
S++S + T E P K +K K +S L + G
Sbjct: 687 FKLS-------STLSTHKIIHTG-------EKPYKCEKCGKAF--NRSSNLIEHKKIHTG 730
Query: 479 VRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAF 538
+ + C C K F S L H RIHT E+P+KC +C +AF S LT H K HTG K +
Sbjct: 731 EQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLY 790
Query: 539 K 539
K
Sbjct: 791 K 791
Score = 216 bits (551), Expect = 1e-55
Identities = 168/601 (27%), Positives = 251/601 (41%), Gaps = 78/601 (12%)
Query: 202 CGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAA 261
C K F K S RH HT ++ FKC ECGK+F L H I HT C C A
Sbjct: 151 CVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKA 210
Query: 262 FSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH--------ISKMHMGGPQ 313
F+ + H +R+++ K Y C EC VF L TH + K G
Sbjct: 211 FNCPSIITKH-KRINTGEK---PYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKA 266
Query: 314 NSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESG 373
+ SS T H + T + ++ A+A + SS L+E + G
Sbjct: 267 FNKSSILTTHKIIRTGEKFYKCKEC-AKAFNQSSN---------------LTEHKKIHPG 310
Query: 374 QSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVS 433
+ P ++ +A + H + + A N S+++
Sbjct: 311 EKPYKCEECG-----------KAFNWPSTLTKHKRIHTGEKPYTCEECGKAFN-QFSNLT 358
Query: 434 NEQTDPTDAEQEKEQESPEKLDK-----KEKKMIKKKSPFLPGSIREENGVRWHVCPYCA 488
+ T + K E E + K KK+ +K P+ C C
Sbjct: 359 THKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYK--------------CEECG 404
Query: 489 KEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 548
K F+ S L H HT EKP+KC +C +AF STLT H + HTG K +KC+ C K+F+
Sbjct: 405 KAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFN 464
Query: 549 TSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH-FKHTELRK-MRHQRK 602
+L H R+HT +P+ C C K F S H+K HI +K E K + K
Sbjct: 465 QFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSK 524
Query: 603 PAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYC 662
+ ++ T ++P + G F + ++ ++PYKC C
Sbjct: 525 LTEHKITHTG--------EKPYKCEECG-----KAFNHFSILTKHKRIHTGEKPYKCEEC 571
Query: 663 HRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAF 722
+A+ +S +L H + HTGEK +KC +CG+ F + L H + HTG K +KC C AF
Sbjct: 572 GKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAF 631
Query: 723 TTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDD 782
+L +H IH + +PY C C K FK S KH H E + ++ +A +
Sbjct: 632 NQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSS 691
Query: 783 S 783
+
Sbjct: 692 T 692
Score = 196 bits (497), Expect = 2e-49
Identities = 108/326 (33%), Positives = 154/326 (47%), Gaps = 18/326 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F + S+L H R HT EKPYKC+ CG+ F S L H+K H K +
Sbjct: 452 KPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYK 511
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
C C +F + LT H TH KPYKC C + F KH + H P
Sbjct: 512 CEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEEC 571
Query: 1084 GE--TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKI----RPQESATVSEK 1137
G+ T+ ++ ++ ++ + + T + T KI +P + +
Sbjct: 572 GKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTH-KKIHTGGKPYKCEECGKA 630
Query: 1138 VLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
S K +I +K + C C K+FK S L +H IHTGEKPYKC
Sbjct: 631 FNQFSTLTKHKIIHTEEKPYK----------CEECGKAFKWSSTLTKHKIIHTGEKPYKC 680
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+ECGK+F + STL H HTG+K + C C AF+ +L H ++HTG +P+KC C
Sbjct: 681 EECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECG 740
Query: 1258 LRFRTSGRRKTHMQFHYKPDPKKARK 1283
F S TH + H K P K ++
Sbjct: 741 KAFNYSSHLNTHKRIHTKEQPYKCKE 766
Score = 192 bits (489), Expect = 2e-48
Identities = 162/670 (24%), Positives = 257/670 (38%), Gaps = 95/670 (14%)
Query: 465 KSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIH-------------THEKPFK 511
K PF ++R R+ C + +K V ++H T K F
Sbjct: 93 KDPFQKATLR-----RYKNCEHKNVHLKKDHKSVDECKVHRGGYNGFNQCLPATQSKIFL 147
Query: 512 CPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKS------------------------- 546
+C +AF S H +HT K FKC+ C KS
Sbjct: 148 FDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKC 207
Query: 547 ---FSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKP 603
F+ + H R++TG +P+ C C K F S TH K R ++ +
Sbjct: 208 GKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTH-----KKNYTRYKLYKCEE 262
Query: 604 AKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFN---NNFVNEADRPYKCF 660
K++I I+ T + + F N + ++ ++PYKC
Sbjct: 263 CGKAFNKSSILT-----THKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCE 317
Query: 661 YCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNG 720
C +A+ L +H R HTGEKP+ C +CG+ F L H R HT K +KC C
Sbjct: 318 ECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGE 377
Query: 721 AFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASI 780
AF+ +L +H IH + +PY C C K FK S +H TH E + ++ +A +
Sbjct: 378 AFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNW 437
Query: 781 DDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLA 840
ST+ + + I + E P EV +L + T A
Sbjct: 438 -PSTLTKHN---------RIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHT---------A 478
Query: 841 DQPLEADEDG-FVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPV 899
++P + +E G + L H E+ P + +T+ P
Sbjct: 479 EKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPY 538
Query: 900 QQLQDSSTLESQALSTSFHQQSLLQAP---------SSDGMNVTTRLIQESSQEELDLQA 950
+ + ++ T + + P + N+TT + ++ +
Sbjct: 539 KCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEE 598
Query: 951 QGSQFLEDNEDQSRRS-------YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRG 1003
G F + + + + Y+C+ C K F + S L +H HT EKPYKC+ CG+
Sbjct: 599 CGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKA 658
Query: 1004 FVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTT 1063
F S L H+ HTG K + C C +F + +L+ H H KPYKC C + F +
Sbjct: 659 FKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRS 718
Query: 1064 VHCKKHMKRH 1073
+ +H K H
Sbjct: 719 SNLIEHKKIH 728
Score = 191 bits (484), Expect = 7e-48
Identities = 105/345 (30%), Positives = 156/345 (45%), Gaps = 28/345 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F S L +H R HTGEKPY C+ CG+ F L +H++ HT K +
Sbjct: 312 KPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYK 371
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ---------- 1074
C+ C +F+ + +LT+H H KPYKC C + F+ + +H H
Sbjct: 372 CTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEEC 431
Query: 1075 ----TVPSAVSATGETEGG------DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLA 1124
PS ++ G ++C + + S+ ++ + EE +
Sbjct: 432 GKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGK-- 489
Query: 1125 KIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC------CTYCPKSFKK 1178
+ T +K+ ++ K K + E K + C C K+F
Sbjct: 490 AFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNH 549
Query: 1179 PSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSL 1238
S L +H RIHTGEKPYKC+ECGK+FT S L H K HTG+K + C C AF+ +L
Sbjct: 550 FSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNL 609
Query: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
H ++HTG KP+KC C F H H + P K +
Sbjct: 610 TTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEE 654
Score = 189 bits (479), Expect = 3e-47
Identities = 108/319 (33%), Positives = 150/319 (47%), Gaps = 37/319 (11%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K FK SS L +H +HTGEKPYKC+ CG+ F +L H++ HTG K +
Sbjct: 507 KKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPY 566
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSAT 1083
C C +FT + +LT H H K YKC C + F + + H K H
Sbjct: 567 KCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHT--------- 617
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
GG EE + S ++ ++I TEE +P + + S
Sbjct: 618 ----GGKPYKCEECGKAFNQFSTLTKHKII-HTEE--------KPYKCEECGKAFKWSST 664
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
K +I +K + C C K+FK S L H IHTGEKPYKC++CGK+
Sbjct: 665 LTKHKIIHTGEKPYK----------CEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKA 714
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F S L H K HTG++ + C C AF+ L H R+HT +P+KC C F
Sbjct: 715 FNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQY 774
Query: 1264 GRRKTHMQFH-----YKPD 1277
TH + H YKP+
Sbjct: 775 SNLTTHNKIHTGEKLYKPE 793
Score = 186 bits (472), Expect = 2e-46
Identities = 108/321 (33%), Positives = 145/321 (45%), Gaps = 34/321 (10%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K FK SS L +H +HTGEKPYKC+ CG+ F L H + HTG K +
Sbjct: 395 KKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPY 454
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-QTVPSAVSA 1082
C VC +F +LT H H + KPYKC C + F + + KH K H + P
Sbjct: 455 KCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEE 514
Query: 1083 TGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQS 1142
G+ S K IT T E +P + + S
Sbjct: 515 CGKAF---------------KWSSKLTEHKITHTGE--------KPYKCEECGKAFNHFS 551
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + +K + C C K+F + S+L H +IHTGEK YKC+ECGK
Sbjct: 552 ILTKHKRIHTGEKPYK----------CEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGK 601
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+FT S L H K HTG K + C C AF+ +L H +HT KP+KC C F+
Sbjct: 602 AFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKW 661
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
S H H P K +
Sbjct: 662 SSTLTKHKIIHTGEKPYKCEE 682
Score = 177 bits (449), Expect = 8e-44
Identities = 103/320 (32%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F SS L H +++T K YKC+ CG+ F S +L +H+ TG K +
Sbjct: 228 KPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYK 287
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + +LT H H KPYKC C + F KH + H TG
Sbjct: 288 CKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIH---------TG 338
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL-VQSA 1143
E +P + Q + + + +EK
Sbjct: 339 E-----------------------KPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTEC 375
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
E S K ++ E K C C K+FK S L H HTGEKPYKC+ECGK+
Sbjct: 376 GEAFSRSSNLTKHKKIHTEKKPYK-CEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKA 434
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F STL H + HTG+K + C VC AF+ +L H R+HT KP+KC C F S
Sbjct: 435 FNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRS 494
Query: 1264 GRRKTHMQFHYKPDPKKARK 1283
H + H + P K +
Sbjct: 495 SNLTKHKKIHIEKKPYKCEE 514
Score = 176 bits (446), Expect = 2e-43
Identities = 104/317 (32%), Positives = 138/317 (43%), Gaps = 32/317 (10%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C+ C K F KSS L H TGEK YKCK C + F S L H+K H G K + C
Sbjct: 258 YKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCE 317
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F +LT+H H KPY C C + F + H KR T T
Sbjct: 318 ECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTH-KRIHTAEKFYKCTE-- 374
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
C E S+ +K E + EE + K S+ ++E L + +
Sbjct: 375 -----CGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKW----SSKLTEHKLTHTGEKP 425
Query: 1147 DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTV 1206
+ C C K+F PS L +H RIHTGEKPYKC+ CGK+F
Sbjct: 426 YK--------------------CEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQ 465
Query: 1207 KSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRR 1266
S L H + HT +K + C C AFS +L H ++H KP+KC C F+ S +
Sbjct: 466 FSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKL 525
Query: 1267 KTHMQFHYKPDPKKARK 1283
H H P K +
Sbjct: 526 TEHKITHTGEKPYKCEE 542
Score = 160 bits (405), Expect = 1e-38
Identities = 95/326 (29%), Positives = 139/326 (42%), Gaps = 35/326 (10%)
Query: 968 RCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSV 1027
+C+ C K F S + +H R +TGEKPY C+ CG+ F S L +H+K +T K + C
Sbjct: 203 KCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEE 262
Query: 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETE 1087
C +F + LT H K YKC C + F + ++ H+ + E
Sbjct: 263 CGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQS----SNLTEHKKIHPGEKPYKCEE 318
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKD 1147
G + +P + Q + + + +EK
Sbjct: 319 CGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYK------- 371
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
CT C ++F + S+L +H +IHT +KPYKC+ECGK+F
Sbjct: 372 ---------------------CTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWS 410
Query: 1208 STLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRK 1267
S L H THTG+K + C C AF+ +L H R+HTG KP+KC C F
Sbjct: 411 SKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLT 470
Query: 1268 THMQFHYKPDPKKAR---KPMTRSSS 1290
TH + H P K K +RSS+
Sbjct: 471 THKRIHTAEKPYKCEECGKAFSRSSN 496
Score = 155 bits (391), Expect = 4e-37
Identities = 95/275 (34%), Positives = 132/275 (48%), Gaps = 22/275 (8%)
Query: 42 CLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGED-PTCPVCNK 100
C+ +F K S RH H K +C +C ++F + +L HK H+ + C C K
Sbjct: 151 CVKAFHKFSNSNRHKISHTEK-KLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGK 209
Query: 101 KFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKK 160
F+ + + H ++ E+ C ECG F S+L H + + + + + C+ C K
Sbjct: 210 AFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTR----YKLYKCEECGK 265
Query: 161 EFETSSELKEHM-----KTHYKIR-------VSSTRSYNRNIDRSGFTYSCPHCGKTFQK 208
F SS L H + YK + SS + ++ I Y C CGK F
Sbjct: 266 AFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNW 325
Query: 209 PSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNL 268
PS LT+H RIHTGE+P+ C ECGKAFNQ L TH HT EK + C C AFS+ NL
Sbjct: 326 PSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNL 385
Query: 269 QSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
H +++H+E K Y C EC FK L H
Sbjct: 386 TKH-KKIHTEKK---PYKCEECGKAFKWSSKLTEH 416
Score = 129 bits (325), Expect = 2e-29
Identities = 69/169 (40%), Positives = 96/169 (56%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE S NL + + ++C EC AFS ++ L H K++H ++ + C
Sbjct: 344 CEECGKAFNQFS-NLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKH-KKIHTEKKPYKCE 401
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAFK ++ L EH TH + +KP +KC+ C KAF PS L +H+RIHTGE+P
Sbjct: 402 ECGKAFKWSSKLTEHKLTH------TGEKP--YKCEECGKAFNWPSTLTKHNRIHTGEKP 453
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C +C KAFNQ S L H + HT E+PYKC C F++ SN+ H K
Sbjct: 454 YKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKK 502
Score = 124 bits (310), Expect = 1e-27
Identities = 66/156 (42%), Positives = 89/156 (57%), Gaps = 9/156 (5%)
Query: 1643 NLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLK 1702
NL + + ++C EC +AFS ++ L H K++H ++ + C C KAFK ++ L
Sbjct: 468 NLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKH-KKIHIEKKPYKCEECGKAFKWSSKLT 526
Query: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
EH TH + +KP +KC+ C KAF S L +H RIHTGE+P+ C C KAF Q
Sbjct: 527 EHKITH------TGEKP--YKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQS 578
Query: 1763 SALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
S L H K HTGE+ YKC C FTQ SN+ H K
Sbjct: 579 SNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKK 614
Score = 121 bits (304), Expect = 5e-27
Identities = 65/169 (38%), Positives = 94/169 (55%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V S L + + ++C EC +AF+ +++L H K + E+ + C
Sbjct: 232 CEECG-KVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTH-KIIRTGEKFYKCK 289
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF ++++L EH + H +KP +KC+ C KAF PS L +H RIHTGE+P
Sbjct: 290 ECAKAFNQSSNLTEHKKIHPG------EKP--YKCEECGKAFNWPSTLTKHKRIHTGEKP 341
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C C KAFNQ S L H + HT E+ YKC C F++ SN+ H K
Sbjct: 342 YTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKK 390
Score = 116 bits (291), Expect = 2e-25
Identities = 60/146 (41%), Positives = 82/146 (56%), Gaps = 9/146 (6%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
E + ++C EC +AF ++ L H K +H E+ + C C KAFK ++ L H H
Sbjct: 646 EEKPYKCEECGKAFKWSSTLTKH-KIIHTGEKPYKCEECGKAFKLSSTLSTHKIIH---- 700
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
+ +KP +KC+ C KAF + S L H +IHTGE+P+ C C KAFN S L H + H
Sbjct: 701 --TGEKP--YKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIH 756
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMK 1798
T E+PYKC C F Q SN+ H K
Sbjct: 757 TKEQPYKCKECGKAFNQYSNLTTHNK 782
Score = 115 bits (287), Expect = 5e-25
Identities = 79/258 (30%), Positives = 119/258 (46%), Gaps = 30/258 (11%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS+L H + HTGEK YKC+ CG+ F S L +H+K HTG K +
Sbjct: 564 KPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F +LT+H H KPYKC C + F+ + KH H TG
Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIH---------TG 674
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRP--QESATVSEKVLVQS 1142
E C EE + + +S S ++I T E+ + K S+ + E + +
Sbjct: 675 EKPYK--C--EECGKAFKLSSTLSTHKII-HTGEKPYKCEKCGKAFNRSSNLIEHKKIHT 729
Query: 1143 AAEKDRISEL-----------RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTG 1191
+ + E K+ +++P C C K+F + S+L H +IHTG
Sbjct: 730 GEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYK---CKECGKAFNQYSNLTTHNKIHTG 786
Query: 1192 EKPYKCDECGKSFTVKST 1209
EK YK ++ T T
Sbjct: 787 EKLYKPEDVTVILTTPQT 804
Score = 111 bits (278), Expect = 6e-24
Identities = 63/167 (37%), Positives = 86/167 (51%), Gaps = 10/167 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + E + ++C EC +AF ++ L H K H E+ + C
Sbjct: 484 CEECG-KAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEH-KITHTGEKPYKCE 541
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF + L +H + H + +KP +KC+ C KAF + S L H +IHTGE+
Sbjct: 542 ECGKAFNHFSILTKHKRIH------TGEKP--YKCEECGKAFTQSSNLTTHKKIHTGEKF 593
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ C C KAF Q S L H K HTG +PYKC C F Q S + H
Sbjct: 594 YKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKH 640
Score = 108 bits (270), Expect = 5e-23
Identities = 53/142 (37%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++L H K +H E+ + C C KAF ++++L H + H
Sbjct: 536 KPYKCEECGKAFNHFSILTKH-KRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTG---- 590
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KC+ C KAF + S L H +IHTG +P+ C C KAFNQ S L H HT
Sbjct: 591 ----EKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTE 646
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F S + H
Sbjct: 647 EKPYKCEECGKAFKWSSTLTKH 668
Score = 108 bits (269), Expect = 6e-23
Identities = 55/142 (38%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF ++++L H + H G
Sbjct: 564 KPYKCEECGKAFTQSSNLTTH-KKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGG--- 619
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
KP +KC+ C KAF + S L +H IHT E+P+ C C KAF S L H HTG
Sbjct: 620 ---KP--YKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTG 674
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F S + H
Sbjct: 675 EKPYKCEECGKAFKLSSTLSTH 696
Score = 103 bits (258), Expect = 1e-21
Identities = 57/156 (36%), Positives = 81/156 (51%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + E + ++C EC +AF ++ L H K H E+ + C C KAF +
Sbjct: 382 SSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEH-KLTHTGEKPYKCEECGKAFNWPST 440
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L +H + H + +KP +KC+ C KAF + S L H RIHT E+P+ C C KAF+
Sbjct: 441 LTKHNRIH------TGEKP--YKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFS 492
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ S L H K H ++PYKC C F S + H
Sbjct: 493 RSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEH 528
Score = 101 bits (252), Expect = 6e-21
Identities = 53/125 (42%), Positives = 74/125 (59%), Gaps = 9/125 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF ++ L H K +H E+ + C C KAF R+++L EH + H
Sbjct: 676 KPYKCEECGKAFKLSSTLSTH-KIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIH------ 728
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ ++P +KC+ C KAF S L H RIHT E+P+ C C KAFNQ S L H K HTG
Sbjct: 729 TGEQP--YKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTG 786
Query: 1775 ERPYK 1779
E+ YK
Sbjct: 787 EKLYK 791
Score = 84.3 bits (207), Expect = 1e-15
Identities = 46/136 (33%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 1661 ECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPR 1720
+C +AF + H K H +++ C C K+F HL +H H +
Sbjct: 150 KCVKAFHKFSNSNRH-KISHTEKKLFKCKECGKSFCMLPHLAQHKIIHT--------RVN 200
Query: 1721 VFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKC 1780
KC+ C KAF PS + +H RI+TGE+P+ C C K FN S L H K +T + YKC
Sbjct: 201 FCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKC 260
Query: 1781 AYCVMGFTQKSNMKLH 1796
C F + S + H
Sbjct: 261 EECGKAFNKSSILTTH 276
Score = 83.6 bits (205), Expect = 2e-15
Identities = 48/146 (32%), Positives = 70/146 (47%), Gaps = 9/146 (6%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
E + +C EC ++F L H K +H R C C KAF + + +H + +
Sbjct: 170 EKKLFKCKECGKSFCMLPHLAQH-KIIHTRVNFCKCEKCGKAFNCPSIITKHKRIN---- 224
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
+ +KP + C+ C K F S+L H + +T + + C C KAFN+ S L H
Sbjct: 225 --TGEKP--YTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIR 280
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMK 1798
TGE+ YKC C F Q SN+ H K
Sbjct: 281 TGEKFYKCKECAKAFNQSSNLTEHKK 306
Score = 78.6 bits (192), Expect = 5e-14
Identities = 33/85 (38%), Positives = 52/85 (61%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C C K F + S+L+ H +IHT E+P+KC +C +AF S L H + HT +
Sbjct: 702 GEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQP 761
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTG 562
+KC+ C K+F+ +L H ++HTG
Sbjct: 762 YKCKECGKAFNQYSNLTTHNKIHTG 786
Score = 76.6 bits (187), Expect = 2e-13
Identities = 39/98 (39%), Positives = 49/98 (50%)
Query: 1172 CPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNA 1231
C K+F K S+ RH HT +K +KC ECGKSF + L H HT C C A
Sbjct: 151 CVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKA 210
Query: 1232 FSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTH 1269
F+ + H R++TG KP+ C C F S R TH
Sbjct: 211 FNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTH 248
Score = 71.6 bits (174), Expect = 7e-12
Identities = 35/101 (34%), Positives = 49/101 (48%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C KSF L +H IHT KC++CGK+F S + H + +TG+K ++C C
Sbjct: 176 CKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEEC 235
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTH 1269
F+ L H + +T K +KC C F S TH
Sbjct: 236 GKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTH 276
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 1691 CRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
C KAF + ++ H +H + ++FKC C K+F L +H IHT
Sbjct: 151 CVKAFHKFSNSNRHKISHT--------EKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFC 202
Query: 1751 HCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSY 1803
C C KAFN S + H + +TGE+PY C C F S + H K Y
Sbjct: 203 KCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRY 255
Score = 41.2 bits (95), Expect = 0.009
Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + + ++C EC +AF+ ++ L H K +H +E+ + C C KAF + ++
Sbjct: 718 SSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTH-KRIHTKEQPYKCKECGKAFNQYSN 776
Query: 1701 LKEHMQTH 1708
L H + H
Sbjct: 777 LTTHNKIH 784
>gi|222831664 zinc finger protein 184 [Homo sapiens]
Length = 751
Score = 254 bits (650), Expect = 4e-67
Identities = 170/558 (30%), Positives = 244/558 (43%), Gaps = 65/558 (11%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F + H R H DKP++CDQC + F +LT H+ H+GE P C
Sbjct: 250 YKCNECEKAFSRSENLINHQRIHT-GDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKC 308
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS+ L H +H E+ C+ECG F+ + H EH++ G + C
Sbjct: 309 DECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRG----HFMEHQKIHTGEKPFKC 364
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F S+ L +H K H + TY C CGK F PS RH
Sbjct: 365 DECDKTFTRSTHLTQHQKIHTGEK----------------TYKCNECGKAFNGPSTFIRH 408
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
IHTGE+P++C+ECGKAF+Q L H HTGEKP+ CA C +FS +L H+ ++
Sbjct: 409 HMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHL-KI 467
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
H+ K Y C EC F SL H ++H S A + L Q
Sbjct: 468 HTGEK---PYKCNECGKAFSYCSSLTQH-RRIHTREKPFECSECGKAFSYLSNLNQH--- 520
Query: 336 QQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQ 395
Q+T Q + + +A + L++ + +G+ P + T ++Q
Sbjct: 521 QKTHTQEKAYECKECGKA----FIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQH 576
Query: 396 ALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQ----TDPTD-AEQEKEQES 450
H + + A N ++ +++ P + AE K
Sbjct: 577 -----------RKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRH 625
Query: 451 PEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPF 510
L + +K ++K + C C K F + S L +H RIHT EKP+
Sbjct: 626 CSSLAQHQKTHTEEKP---------------YQCNKCEKTFSQSSHLTQHQRIHTGEKPY 670
Query: 511 KCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPH 570
KC +C +AF+ + LT H THTG K + C C K+FS S L H R+H+G +PF C
Sbjct: 671 KCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCND 730
Query: 571 CDKKFRTSGHRKTHIASH 588
C K FR H H
Sbjct: 731 CGKSFRYRSALNKHQRLH 748
Score = 235 bits (600), Expect = 3e-61
Identities = 169/617 (27%), Positives = 255/617 (41%), Gaps = 86/617 (13%)
Query: 107 SLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSS 166
S+K + +KE++ C+ECG F+ S L H H G + + C C+K F S
Sbjct: 208 SIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTH----TGEKPYKCNECEKAFSRSE 263
Query: 167 ELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFK 226
L H + H + Y C CGK F + LT+H RIHTGE+P+K
Sbjct: 264 NLINHQRIHTGDK----------------PYKCDQCGKGFIEGPSLTQHQRIHTGEKPYK 307
Query: 227 CSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYN 286
C ECGKAF+Q+ L H HTGEKP+ C C AFSQ+G+ H Q++H+ K +
Sbjct: 308 CDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEH-QKIHTGEK---PFK 363
Query: 287 CTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSAS 346
C EC F L H K+H G + A +T + + E
Sbjct: 364 CDECDKTFTRSTHLTQH-QKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGE------- 415
Query: 347 SQPSSQAVSDVIQQLLELSEPAPVESGQSP----QPGQQLSITVGINQDILQQALENSGL 402
Q L++ +G+ P + G+ S + Q + E
Sbjct: 416 KPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYK 475
Query: 403 SSIPAAAHPNDSCHAKTSAPHAQNP--DVSSVSNEQTDPTDAEQEKEQESPEK-LDKKEK 459
+ A S + H + + S + ++ Q ++ + EK + KE
Sbjct: 476 CNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKEC 535
Query: 460 KMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAF 519
+S L R G + + C C K F S L++H +IHT E+P+KC +C RAF
Sbjct: 536 GKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAF 595
Query: 520 AVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG 579
LT H + HTG K ++C C K+F SL H + HT +P+ C C+K F S
Sbjct: 596 NQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSS 655
Query: 580 HRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQ 639
H H ++ G+ +P N+
Sbjct: 656 HLTQH-------------------QRIHTGE----------------------KPYKCNE 674
Query: 640 FFQSYFNNNFVNE------ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG 693
+++ + + E ++PY C C + + +S +L QH R H+GEKPF C+ CG+
Sbjct: 675 CDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKS 734
Query: 694 FVSAGVLKAHIRTHTGL 710
F L H R H G+
Sbjct: 735 FRYRSALNKHQRLHPGI 751
Score = 224 bits (571), Expect = 6e-58
Identities = 160/609 (26%), Positives = 255/609 (41%), Gaps = 66/609 (10%)
Query: 430 SSVSNEQTDPTDAEQEKEQESPEKLDKKEKKM----IKKKSPFLPGSIREEN---GVRWH 482
S++ ++ P + ++ + KKEK K + IR + G + +
Sbjct: 191 SNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPY 250
Query: 483 VCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQY 542
C C K F + +L+ H RIHT +KP+KC QC + F +LT H + HTG K +KC
Sbjct: 251 KCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDE 310
Query: 543 CMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH-----FKHTELRKM 597
C K+FS L H R+HTG +P+ C C K F GH H H FK E K
Sbjct: 311 CGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKT 370
Query: 598 ----RHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEA 653
H + K+ G ++ + G P ++ ++ ++
Sbjct: 371 FTRSTHLTQHQKIHTG-----------EKTYKCNECGKAFNGPS-----TFIRHHMIHTG 414
Query: 654 DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSF 713
++PY+C C +A+ + +L QH ++HTGEKP+ C++CG+ F L H++ HTG K +
Sbjct: 415 EKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPY 474
Query: 714 KCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQ 773
KC C AF+ SL +H IH +P+ C C K F N +H KTH E A + ++
Sbjct: 475 KCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKE 534
Query: 774 HQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEA 833
+A S + I + E P L + T E
Sbjct: 535 CGKAFIRSSSLAKHE----------RIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGE- 583
Query: 834 GLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQ 893
+P + +E G Q+ H+ Q + + +E A + F + Q
Sbjct: 584 --------RPYKCNECGRAFNQNI---HLTQHKRIHTGAKPYECAECGKAFRHCSSLAQH 632
Query: 894 PQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGS 953
+ ++ + E + S S H + + + + E D S
Sbjct: 633 QKTHTEEKPYQCNKCE-KTFSQSSHLTQHQRIHTGE---------KPYKCNECDKAFSRS 682
Query: 954 QFLED--NEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLK 1011
L + N + Y C+ C K F +S++L QH R H+GEKP+ C CG+ F L
Sbjct: 683 THLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALN 742
Query: 1012 SHEKTHTGV 1020
H++ H G+
Sbjct: 743 KHQRLHPGI 751
Score = 198 bits (504), Expect = 4e-50
Identities = 114/349 (32%), Positives = 156/349 (44%), Gaps = 35/349 (10%)
Query: 931 MNVTTRLI-QESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSH 989
+NV++ L+ QE S EE + Q N + +S +C+ C K F S L +H R+H
Sbjct: 187 VNVSSNLVTQEPSPEETSTKRSIKQ--NSNPVKKEKSCKCNECGKAFSYCSALIRHQRTH 244
Query: 990 TGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMK 1049
TGEKPYKC C + F S L +H++ HTG K + C C F SLT+H H K
Sbjct: 245 TGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEK 304
Query: 1050 PYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSR 1109
PYKC C + F H +H + H TGE +
Sbjct: 305 PYKCDECGKAFSQRTHLVQHQRIH---------TGE-----------------------K 332
Query: 1110 PEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCC 1169
P + +Q + EK +K Q + + C
Sbjct: 333 PYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKC 392
Query: 1170 TYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCS 1229
C K+F PS +RH IHTGEKPY+C+ECGK+F+ S L H KTHTG+K + C C
Sbjct: 393 NECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECG 452
Query: 1230 NAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP 1278
+FS SL H+++HTG KP+KC C F H + H + P
Sbjct: 453 KSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTREKP 501
Score = 196 bits (499), Expect = 1e-49
Identities = 151/579 (26%), Positives = 234/579 (40%), Gaps = 66/579 (11%)
Query: 711 KSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQ 770
KS KC C AF+ +L RH H +PY C C+K F S N H + H + +
Sbjct: 220 KSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYK 279
Query: 771 LQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGT 830
Q + S Q + + + DE + + H+V
Sbjct: 280 CDQCGKGFIEGPSLTQHQRIHTGEK---PYKCDECGKAFS------------QRTHLVQH 324
Query: 831 EEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTD-- 888
+ G++ P +E G Q RGH + ++ ++ F+ + FT +
Sbjct: 325 QRIHTGEK----PYTCNECGKAFSQ---RGHFMEHQKIHTGEKPFKCDECDKTFTRSTHL 377
Query: 889 TYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDL 948
T HQ+ T + +F+ S + +I + ++ +
Sbjct: 378 TQHQKIH-------TGEKTYKCNECGKAFNGPSTF---------IRHHMIH-TGEKPYEC 420
Query: 949 QAQGSQFLEDNE-------DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCG 1001
G F + + + Y C C K F S L QH++ HTGEKPYKC CG
Sbjct: 421 NECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECG 480
Query: 1002 RGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFR 1061
+ F L H + HT K F CS C +F+ +L +H TH K Y+C C + F
Sbjct: 481 KAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFI 540
Query: 1062 TTVHCKKHMKRHQ-TVPSAVSATGETEG-GDICMEEEEEHSDR-----NASRKSRPEVIT 1114
+ KH + H P G+T G ++ + H+ N ++ + I
Sbjct: 541 RSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIH 600
Query: 1115 FTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPK 1174
T+ + +P E A + S+ + + + +K + C C K
Sbjct: 601 LTQHKRIHTGA-KPYECAECGKAFRHCSSLAQHQKTHTEEKPYQ----------CNKCEK 649
Query: 1175 SFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFST 1234
+F + S L +H RIHTGEKPYKC+EC K+F+ + L H THTG+K ++C+ C FS
Sbjct: 650 TFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQ 709
Query: 1235 KGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFH 1273
L H R+H+G KPF C C FR H + H
Sbjct: 710 STYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLH 748
Score = 192 bits (488), Expect = 3e-48
Identities = 114/353 (32%), Positives = 166/353 (47%), Gaps = 29/353 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+CD C K F + +HL QH R HTGEKPY C CG+ F G H+K HTG K F
Sbjct: 304 KPYKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFK 363
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFR-TTVHCKKHMKRHQTVPSAVSAT 1083
C C+ +FT + LT+H H K YKC C + F + + HM P +
Sbjct: 364 CDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNEC 423
Query: 1084 GE--TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKI----RPQESATVSEK 1137
G+ ++ ++ ++ ++ + ++ AQ KI +P + +
Sbjct: 424 GKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYW-SSLAQHLKIHTGEKPYKCNECGKA 482
Query: 1138 VLVQSAAEKDRISELRDKQAEL--------------QDEPKH----ANCCTYCPKSFKKP 1179
S+ + R R+K E Q + H A C C K+F +
Sbjct: 483 FSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRS 542
Query: 1180 SDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLK 1239
S L +H RIHTGEKPY+C ECGK+F+ S+L H K HTG++ + C+ C AF+ L
Sbjct: 543 SSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLT 602
Query: 1240 VHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP---KKARKPMTRSS 1289
H R+HTGAKP++C C FR H + H + P K K ++SS
Sbjct: 603 QHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSS 655
Score = 187 bits (474), Expect = 1e-46
Identities = 105/340 (30%), Positives = 152/340 (44%), Gaps = 15/340 (4%)
Query: 950 AQGSQFLEDNEDQS-RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSG 1008
+Q F+E + + + ++CD C+K F +S+HL QH + HTGEK YKC CG+ F
Sbjct: 344 SQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPS 403
Query: 1009 VLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKK 1068
H HTG K + C+ C +F+ + +LT+H TH KPY C C + F +
Sbjct: 404 TFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQ 463
Query: 1069 HMKRHQTVPSAVSATGE-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQL 1123
H+K H TGE E G R + +P + + + L
Sbjct: 464 HLKIH---------TGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYL 514
Query: 1124 AKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLV 1183
+ + + EK K I + E + C C K+F S L+
Sbjct: 515 SNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLI 574
Query: 1184 RHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMR 1243
+H +IHTGE+PYKC+ECG++F L H + HTG K + C C AF SL H +
Sbjct: 575 QHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQK 634
Query: 1244 LHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
HT KP++C CE F S H + H P K +
Sbjct: 635 THTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNE 674
Score = 168 bits (426), Expect = 4e-41
Identities = 100/315 (31%), Positives = 141/315 (44%), Gaps = 6/315 (1%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F + S+L QH ++HTGEKPY C CG+ F L H K HTG K +
Sbjct: 416 KPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYK 475
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F+ SLT+H H KP++C C + F + +H K H T A
Sbjct: 476 CNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTH-TQEKAYECK- 533
Query: 1085 ETEGGDICMEEEEEHSDRNASRKS-RPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E I +H + K + T + L + R + K
Sbjct: 534 ECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGR 593
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
A I + K+ +P C C K+F+ S L +H + HT EKPY+C++C K+
Sbjct: 594 AFNQNIHLTQHKRIHTGAKPYE---CAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKT 650
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F+ S L H + HTG+K + C+ C AFS L H HTG KP+ C C F S
Sbjct: 651 FSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQS 710
Query: 1264 GRRKTHMQFHYKPDP 1278
H + H P
Sbjct: 711 TYLIQHQRIHSGEKP 725
Score = 162 bits (410), Expect = 3e-39
Identities = 93/284 (32%), Positives = 129/284 (45%), Gaps = 34/284 (11%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ + C C K F S+L QH ++HT EK Y+CK CG+ F+ S L HE+ HTG K +
Sbjct: 500 KPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQ 559
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTV-PSAVSAT 1083
C C +F+ SL +H H +PYKC C F +H +H + H P +
Sbjct: 560 CHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAEC 619
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
G+ H A + T TEE+ Q K EK QS
Sbjct: 620 GKAF----------RHCSSLAQHQK-----THTEEKPYQCNKC---------EKTFSQS- 654
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
S L Q E + C C K+F + + L H HTGEKPY C+EC K+
Sbjct: 655 ------SHLTQHQRIHTGEKPYK--CNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKT 706
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTG 1247
F+ + L H + H+G+K F C+ C +F + +L H RLH G
Sbjct: 707 FSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLHPG 750
Score = 123 bits (309), Expect = 1e-27
Identities = 60/144 (41%), Positives = 79/144 (54%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AFS M H K +H E+ C C K F R+THL +H + H
Sbjct: 332 KPYTCNECGKAFSQRGHFMEHQK-IHTGEKPFKCDECDKTFTRSTHLTQHQKIHTG---- 386
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KC+ C KAF PS RH IHTGE+P+ C C KAF+Q S L H K HTG
Sbjct: 387 ----EKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTG 442
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY CA C F+ S++ H+K
Sbjct: 443 EKPYDCAECGKSFSYWSSLAQHLK 466
Score = 123 bits (308), Expect = 2e-27
Identities = 63/194 (32%), Positives = 102/194 (52%), Gaps = 21/194 (10%)
Query: 1625 SASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRER 1684
S++ +E + + ++ + P K+ ++ +C EC +AFS + L+ H + H E+
Sbjct: 190 SSNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQR-THTGEK 248
Query: 1685 IHGCPVCRKAFKRATHLKEHMQTHQA---------------GPSLSSQK-----PRVFKC 1724
+ C C KAF R+ +L H + H GPSL+ + + +KC
Sbjct: 249 PYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKC 308
Query: 1725 DTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCV 1784
D C KAF++ + L +H RIHTGE+P+ C C KAF+Q+ H K HTGE+P+KC C
Sbjct: 309 DECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECD 368
Query: 1785 MGFTQKSNMKLHMK 1798
FT+ +++ H K
Sbjct: 369 KTFTRSTHLTQHQK 382
Score = 119 bits (299), Expect = 2e-26
Identities = 60/150 (40%), Positives = 85/150 (56%), Gaps = 10/150 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L H + +H RE+ C C KAF ++L +H +TH
Sbjct: 472 KPYKCNECGKAFSYCSSLTQH-RRIHTREKPFECSECGKAFSYLSNLNQHQKTHT----- 525
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ + ++C C KAF + S L +H RIHTGE+P+ C C K F+ S+L H K HTG
Sbjct: 526 ---QEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTG 582
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYA 1804
ERPYKC C F Q ++ H KR H+ A
Sbjct: 583 ERPYKCNECGRAFNQNIHLTQH-KRIHTGA 611
Score = 118 bits (296), Expect = 5e-26
Identities = 58/148 (39%), Positives = 87/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
R ++C EC RAF+ L H K +H + + C C KAF+ + L +H +TH
Sbjct: 584 RPYKCNECGRAFNQNIHLTQH-KRIHTGAKPYECAECGKAFRHCSSLAQHQKTH------ 636
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C+ CEK F++ S L +H RIHTGE+P+ C C+KAF++ + L H HTG
Sbjct: 637 TEEKP--YQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTG 694
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C C F+Q + + H +R HS
Sbjct: 695 EKPYNCNECRKTFSQSTYLIQH-QRIHS 721
Score = 117 bits (294), Expect = 8e-26
Identities = 56/151 (37%), Positives = 79/151 (52%), Gaps = 15/151 (9%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C K F + L +H RIHTGEKPYKCDECGK+F+ ++ L H + HTG+K ++C+ C
Sbjct: 280 CDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNEC 339
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRS 1288
AFS +G H ++HTG KPFKC C+ F S H + H
Sbjct: 340 GKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIH--------------- 384
Query: 1289 SSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQ 1319
+ E N + P+ FI ++ + TG+
Sbjct: 385 TGEKTYKCNECGKAFNGPSTFIRHHMIHTGE 415
Score = 111 bits (278), Expect = 6e-24
Identities = 49/144 (34%), Positives = 81/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF + L H K H E+ + C C K F +++HL +H + H
Sbjct: 612 KPYECAECGKAFRHCSSLAQHQK-THTEEKPYQCNKCEKTFSQSSHLTQHQRIH------ 664
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C+KAF++ + L H HTGE+P++C C K F+Q + L H + H+G
Sbjct: 665 TGEKP--YKCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSG 722
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+P+ C C F +S + H +
Sbjct: 723 EKPFGCNDCGKSFRYRSALNKHQR 746
Score = 110 bits (275), Expect = 1e-23
Identities = 56/141 (39%), Positives = 80/141 (56%), Gaps = 9/141 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC +AFS + L H K H +E+ + C C KAF R++ L +H + H + +
Sbjct: 503 ECSECGKAFSYLSNLNQHQK-THTQEKAYECKECGKAFIRSSSLAKHERIH------TGE 555
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP ++C C K F+ S L +H +IHTGERP+ C C +AFNQ L H + HTG +P
Sbjct: 556 KP--YQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKP 613
Query: 1778 YKCAYCVMGFTQKSNMKLHMK 1798
Y+CA C F S++ H K
Sbjct: 614 YECAECGKAFRHCSSLAQHQK 634
Score = 109 bits (273), Expect = 2e-23
Identities = 63/195 (32%), Positives = 96/195 (49%), Gaps = 15/195 (7%)
Query: 1643 NLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLK 1702
NL + + +A++C EC +AF ++ L H + +H E+ + C C K F + L
Sbjct: 516 NLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHER-IHTGEKPYQCHECGKTFSYGSSLI 574
Query: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
+H + H R +KC+ C +AF + L +H RIHTG +P+ C C KAF
Sbjct: 575 QHRKIHTG--------ERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHC 626
Query: 1763 SALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELS 1822
S+L H K HT E+PY+C C F+Q S++ H +R H+ E + + S
Sbjct: 627 SSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQH-QRIHT-----GEKPYKCNECDKAFS 680
Query: 1823 RTLHLEEVVQEAAGE 1837
R+ HL E GE
Sbjct: 681 RSTHLTEHQNTHTGE 695
Score = 108 bits (270), Expect = 5e-23
Identities = 71/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 1057 EEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFT 1116
EE V +KH KR + S + + E EG +E ++ A++++ P+ I T
Sbjct: 118 EEELSPEVIVEKH-KRDDSWSSNLLESWEYEGS---LERQQ------ANQQTLPKEIKVT 167
Query: 1117 EEETAQLAKIRPQ----ESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYC 1172
E+ K +S VS ++ Q + ++ ++ KQ + + + C C
Sbjct: 168 EKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNEC 227
Query: 1173 PKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAF 1232
K+F S L+RH R HTGEKPYKC+EC K+F+ L H + HTG K + C C F
Sbjct: 228 GKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGF 287
Query: 1233 STKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP 1278
SL H R+HTG KP+KC C F H + H P
Sbjct: 288 IEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKP 333
Score = 107 bits (268), Expect = 8e-23
Identities = 60/183 (32%), Positives = 100/183 (54%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ + + H +H E+ + C C KAF + ++L +H +TH
Sbjct: 388 KTYKCNECGKAFNGPSTFIRHHM-IHTGEKPYECNECGKAFSQHSNLTQHQKTH------ 440
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C K+F+ S L +H +IHTGE+P+ C C KAF+ S+L H + HT
Sbjct: 441 TGEKP--YDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTR 498
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+P++C+ C F+ SN+ H K H+ QE A ++ G+ R+ L + +
Sbjct: 499 EKPFECSECGKAFSYLSNLNQHQK-THT-----QEKAYECKECGKAFIRSSSLAKHERIH 552
Query: 1835 AGE 1837
GE
Sbjct: 553 TGE 555
Score = 103 bits (258), Expect = 1e-21
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 9/132 (6%)
Query: 1643 NLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLK 1702
+LA + E + +QC +C++ FS ++ L H + +H E+ + C C KAF R+THL
Sbjct: 628 SLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQR-IHTGEKPYKCNECDKAFSRSTHLT 686
Query: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
EH TH + +KP + C+ C K F++ + L +H RIH+GE+PF C C K+F +
Sbjct: 687 EHQNTH------TGEKP--YNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYR 738
Query: 1763 SALQVHMKKHTG 1774
SAL H + H G
Sbjct: 739 SALNKHQRLHPG 750
Score = 90.5 bits (223), Expect = 1e-17
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
Query: 160 KEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIH 219
K SS L + + + N N + + C CGK F S L RH R H
Sbjct: 185 KSVNVSSNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTH 244
Query: 220 TGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEV 279
TGE+P+KC+EC KAF++ L H HTG+KP+ C C F + +L H QR+H+
Sbjct: 245 TGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQH-QRIHTGE 303
Query: 280 KNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
K Y C EC F L H ++H G
Sbjct: 304 K---PYKCDECGKAFSQRTHLVQH-QRIHTG 330
>gi|55742736 zinc finger protein 700 [Homo sapiens]
Length = 742
Score = 251 bits (642), Expect = 4e-66
Identities = 171/626 (27%), Positives = 269/626 (42%), Gaps = 47/626 (7%)
Query: 443 EQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIR 502
E ++ P K + + K + P + R+ G + + C C K F S + RH+
Sbjct: 155 EYQEYGPKPYKCQQPKNKKAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMV 214
Query: 503 IHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTG 562
+H+ + +KC C +AF S H +THTG K ++C+ C KSF+ S +L++H R HTG
Sbjct: 215 MHSGDGTYKCKFCGKAFHSFSLYLIHERTHTGEKPYECKQCGKSFTYSATLQIHERTHTG 274
Query: 563 VRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQ 621
+P+ C CDK F +S H SH KP + + GK +
Sbjct: 275 EKPYECSKCDKAFHSSSSYHRHERSHMGE----------KPYQCKECGKAFAYTSSLRRH 324
Query: 622 EPILITDLGLIQPIPKNQFFQ------SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQH 675
E T G +P Q+ + S+ + +N +RPYKC C + + + + H
Sbjct: 325 ER---THSGK-KPYECKQYGEGLSYLISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTH 380
Query: 676 IRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
++HTGEK +KC QCG+ F + + H R HTG K ++C C AF + LR H G H
Sbjct: 381 EKTHTGEKRYKCKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTH 440
Query: 736 NDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQ 795
+PY C C K F+++ + + H +TH E + ++ +A V + T+
Sbjct: 441 TGEKPYECKECGKAFRSTSHLRVHGRTHTGEKPYECKECGKAFRY----VKHLQIHERTE 496
Query: 796 MQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDG-FVAP 854
+ + S E P + + + T E +P E ++ G
Sbjct: 497 KHIRMPSGERPYKCSICEKGFYSAKSFQTHEKTHTGE---------KPYECNQCGKAFRC 547
Query: 855 QDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALS 914
+ LR H E ++ +E + F + ++ E +
Sbjct: 548 CNSLRYH----ERTHTGEKPYECKQCGKAFRSASHLRMHERTHTGEK-----PYECKQCG 598
Query: 915 TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNK 974
+F S L+ G T E Q ++ + + + + Y C C K
Sbjct: 599 KAFSCASNLR---KHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTGEKPYECKECEK 655
Query: 975 GFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTT 1034
F K S + H R H GEKPY+CK CG GF S+ +L+ H +TH G K + C C +F
Sbjct: 656 AFCKFSSFQIHERKHRGEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNY 715
Query: 1035 NGSLTRHMATHMSMKPYKCPFCEEGF 1060
SL H THM KPY+C C + F
Sbjct: 716 FSSLHIHARTHMGEKPYECKDCGKAF 741
Score = 238 bits (608), Expect = 3e-62
Identities = 170/667 (25%), Positives = 269/667 (40%), Gaps = 85/667 (12%)
Query: 60 ERNDKPHRCDQCP--QTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHE 116
E KP++C Q + F ++ + H+GE P C VC K F +S++ H+++H
Sbjct: 158 EYGPKPYKCQQPKNKKAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMHS 217
Query: 117 KEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHY 176
+ C CG F S +H H G + + CK C K F S+ L+ H +TH
Sbjct: 218 GDGTYKCKFCGKAFHSFSLYLIHERTH----TGEKPYECKQCGKSFTYSATLQIHERTHT 273
Query: 177 KIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQ 236
+ Y C C K F S RH R H GE+P++C ECGKAF
Sbjct: 274 GEK----------------PYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAY 317
Query: 237 KGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKS 296
+L+ H H+G+KP+ C S + Q+H++ E Y C C F S
Sbjct: 318 TSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSGE----RPYKCKICGKGFYS 373
Query: 297 LGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSD 356
S TH K H G + A L+++ + + + +
Sbjct: 374 AKSFQTH-EKTHTGEKRYKCKQCGKAFNLSSSF-------RYHERIHTGEKPYECKQCGK 425
Query: 357 VIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCH 416
+ +L +G+ P ++ +A ++ + H + +
Sbjct: 426 AFRSASQLRVHGGTHTGEKPYECKECG-----------KAFRSTSHLRVHGRTHTGEKPY 474
Query: 417 AKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREE 476
A +E+T+ E+ P K EK KS +
Sbjct: 475 ECKECGKAFRYVKHLQIHERTEKHIRMPSGER--PYKCSICEKGFYSAKS--FQTHEKTH 530
Query: 477 NGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIK 536
G + + C C K FR + L H R HT EKP++C QC +AF S L H +THTG K
Sbjct: 531 TGEKPYECNQCGKAFRCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMHERTHTGEK 590
Query: 537 AFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRK 596
++C+ C K+FS + +L+ H R HTG +P+ C C K FR++ + + H +H
Sbjct: 591 PYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTGEKPYEC 650
Query: 597 MRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRP 656
++ K F S+ + + ++P
Sbjct: 651 KECEKAFCK-----------------------------------FSSFQIHERKHRGEKP 675
Query: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716
Y+C +C + + L+ H R+H GEK ++C +CG+ F L H RTH G K ++C
Sbjct: 676 YECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNYFSSLHIHARTHMGEKPYECK 735
Query: 717 ICNGAFT 723
C AF+
Sbjct: 736 DCGKAFS 742
Score = 197 bits (500), Expect = 1e-49
Identities = 152/551 (27%), Positives = 220/551 (39%), Gaps = 69/551 (12%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C +F S + H R H +KP+ C QC ++F L +H+ TH+GE P C
Sbjct: 222 YKCKFCGKAFHSFSLYLIHERTHT-GEKPYECKQCGKSFTYSATLQIHERTHTGEKPYEC 280
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVH---------------- 139
C+K F +S H H E+ C ECG F S L H
Sbjct: 281 SKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYG 340
Query: 140 --------MEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YKIR------- 179
+ H + +G R + CK C K F ++ + H KTH YK +
Sbjct: 341 EGLSYLISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKRYKCKQCGKAFN 400
Query: 180 VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
+SS+ Y+ I Y C CGK F+ SQL H HTGE+P++C ECGKAF
Sbjct: 401 LSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFRSTSH 460
Query: 240 LQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQ-RVHSEVKNGP-TYNCTECSCVFKSL 297
L+ H HTGEKP+ C C AF +LQ H + H + +G Y C+ C F S
Sbjct: 461 LRVHGRTHTGEKPYECKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKCSICEKGFYSA 520
Query: 298 GSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDV 357
S TH K H G + A F+ + + + +
Sbjct: 521 KSFQTH-EKTHTGEKPYECNQCGKA-------FRCCNSLRYHERTHTGEKPYECKQCGKA 572
Query: 358 IQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHA 417
+ L +G+ P +Q ++ + ++G C
Sbjct: 573 FRSASHLRMHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPY--------ECKQ 624
Query: 418 KTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREEN 477
A S SN Q E+ E P + + EK K S R+
Sbjct: 625 CGKA-------FRSASNLQMH----ERTHTGEKPYECKECEKAFCKFSS--FQIHERKHR 671
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C +C F L H R H EK ++C +C +AF S+L H +TH G K
Sbjct: 672 GEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNYFSSLHIHARTHMGEKP 731
Query: 538 FKCQYCMKSFS 548
++C+ C K+FS
Sbjct: 732 YECKDCGKAFS 742
Score = 191 bits (486), Expect = 4e-48
Identities = 108/327 (33%), Positives = 155/327 (47%), Gaps = 8/327 (2%)
Query: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
+ R Y+C C KGF + + H ++HTGEK YKCK CG+ F S + HE+ HTG
Sbjct: 356 NSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKRYKCKQCGKAFNLSSSFRYHERIHTGE 415
Query: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSA 1079
K + C C +F + L H TH KPY+C C + FR+T H + H + H P
Sbjct: 416 KPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFRSTSHLRVHGRTHTGEKPYE 475
Query: 1080 VSATGET--EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEK 1137
G+ + + E E R S + RP + E+ + E EK
Sbjct: 476 CKECGKAFRYVKHLQIHERTEKHIRMPSGE-RPYKCSICEKGFYSAKSFQTHEKTHTGEK 534
Query: 1138 VLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
+ K + LR + E + C C K+F+ S L H R HTGEKPY
Sbjct: 535 PYECNQCGKAFRCCNSLRYHERTHTGEKPYE--CKQCGKAFRSASHLRMHERTHTGEKPY 592
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
+C +CGK+F+ S L H +THTG+K + C C AF + +L++H R HTG KP++C
Sbjct: 593 ECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTGEKPYECKE 652
Query: 1256 CELRFRTSGRRKTHMQFHYKPDPKKAR 1282
CE F + H + H P + +
Sbjct: 653 CEKAFCKFSSFQIHERKHRGEKPYECK 679
Score = 187 bits (476), Expect = 6e-47
Identities = 112/320 (35%), Positives = 149/320 (46%), Gaps = 39/320 (12%)
Query: 966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025
+Y+C +C K F S H R+HTGEKPY+CK CG+ F S L+ HE+THTG K + C
Sbjct: 221 TYKCKFCGKAFHSFSLYLIHERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKPYEC 280
Query: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATG 1084
S C+ +F ++ S RH +HM KPY+C C + F T ++H + H P G
Sbjct: 281 SKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYG 340
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G + + H N+ + K + S K
Sbjct: 341 E---GLSYLISFQTHIRMNSGERP---------------YKCKICGKGFYSAKSF--QTH 380
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
EK E R K C C K+F S H RIHTGEKPY+C +CGK+F
Sbjct: 381 EKTHTGEKRYK-------------CKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGKAF 427
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
S L H THTG+K + C C AF + L+VH R HTG KP++C C F
Sbjct: 428 RSASQLRVHGGTHTGEKPYECKECGKAFRSTSHLRVHGRTHTGEKPYECKECGKAF---- 483
Query: 1265 RRKTHMQFHYKPDPKKARKP 1284
R H+Q H + + K R P
Sbjct: 484 RYVKHLQIHERTE-KHIRMP 502
Score = 187 bits (476), Expect = 6e-47
Identities = 105/313 (33%), Positives = 145/313 (46%), Gaps = 6/313 (1%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F SS + H R HTGEKPY+CK CG+ F S+ L+ H THTG K +
Sbjct: 388 KRYKCKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYE 447
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMK--RHQTVPSAVSA 1082
C C +F + L H TH KPY+C C + FR H + H + +H +PS
Sbjct: 448 CKECGKAFRSTSHLRVHGRTHTGEKPYECKECGKAFRYVKHLQIHERTEKHIRMPSGERP 507
Query: 1083 --TGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
E G + + H + K P + +R E EK
Sbjct: 508 YKCSICEKGFYSAKSFQTHEKTHTGEK--PYECNQCGKAFRCCNSLRYHERTHTGEKPYE 565
Query: 1141 QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K S + E + C C K+F S+L +H R HTGEKPY+C +C
Sbjct: 566 CKQCGKAFRSASHLRMHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQC 625
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F S L H +THTG+K + C C AF S ++H R H G KP++C HC F
Sbjct: 626 GKAFRSASNLQMHERTHTGEKPYECKECEKAFCKFSSFQIHERKHRGEKPYECKHCGNGF 685
Query: 1261 RTSGRRKTHMQFH 1273
++ + H + H
Sbjct: 686 TSAKILQIHARTH 698
Score = 180 bits (457), Expect = 1e-44
Identities = 103/344 (29%), Positives = 157/344 (45%), Gaps = 29/344 (8%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y C +G + H+R ++GE+PYKCK+CG+GF S+ ++HEKTHTG K +
Sbjct: 331 KKPYECKQYGEGLSYLISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKRY 390
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ--------- 1074
C C +F + S H H KPY+C C + FR+ + H H
Sbjct: 391 KCKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKE 450
Query: 1075 -----TVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQ 1129
S + G T G+ E +E + ++ TE+ + RP
Sbjct: 451 CGKAFRSTSHLRVHGRTHTGEKPYECKE--CGKAFRYVKHLQIHERTEKHIRMPSGERPY 508
Query: 1130 ESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIH 1189
+ + + + + + +K E C C K+F+ + L H R H
Sbjct: 509 KCSICEKGFYSAKSFQTHEKTHTGEKPYE----------CNQCGKAFRCCNSLRYHERTH 558
Query: 1190 TGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
TGEKPY+C +CGK+F S L H +THTG+K + C C AFS +L+ H R HTG K
Sbjct: 559 TGEKPYECKQCGKAFRSASHLRMHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEK 618
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
P++C C FR++ + H + H P K+ K + SS
Sbjct: 619 PYECKQCGKAFRSASNLQMHERTHTGEKPYECKECEKAFCKFSS 662
Score = 170 bits (431), Expect = 1e-41
Identities = 100/302 (33%), Positives = 137/302 (45%), Gaps = 38/302 (12%)
Query: 965 RSYRCDYCNKGFKKSSHLK------QHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHT 1018
+ Y C C K F+ HL+ +H+R +GE+PYKC +C +GF S+ ++HEKTHT
Sbjct: 472 KPYECKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKTHT 531
Query: 1019 GVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPS 1078
G K + C+ C +F SL H TH KPY+C C + FR+ H + H + H
Sbjct: 532 GEKPYECNQCGKAFRCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMHERTH----- 586
Query: 1079 AVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKV 1138
TGE C + + S + RK T T E +P E +
Sbjct: 587 ----TGEKPYE--CKQCGKAFSCASNLRKHGR---THTGE--------KPYECKQCGKAF 629
Query: 1139 LVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
S + + +K E C C K+F K S H R H GEKPY+C
Sbjct: 630 RSASNLQMHERTHTGEKPYE----------CKECEKAFCKFSSFQIHERKHRGEKPYECK 679
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
CG FT L H +TH G+K + C C AF+ SL +H R H G KP++C C
Sbjct: 680 HCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNYFSSLHIHARTHMGEKPYECKDCGK 739
Query: 1259 RF 1260
F
Sbjct: 740 AF 741
Score = 164 bits (416), Expect = 6e-40
Identities = 102/367 (27%), Positives = 148/367 (40%), Gaps = 48/367 (13%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
+ + + Y C C K F S+ L+ H R+HTGEKPY+C C + F SS HE+
Sbjct: 239 IHERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHER 298
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-- 1073
+H G K + C C +F SL RH TH KPY+C EG + + H++ +
Sbjct: 299 SHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSG 358
Query: 1074 -QTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESA 1132
+ + G E+ ++ K + + + R E
Sbjct: 359 ERPYKCKICGKGFYSAKSFQTHEKTHTGEKRYKCKQCGKAFNLS-------SSFRYHERI 411
Query: 1133 TVSEK--VLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHT 1190
EK Q S+LR E + C C K+F+ S L H R HT
Sbjct: 412 HTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYE--CKECGKAFRSTSHLRVHGRTHT 469
Query: 1191 GEKPYKCDECGKSFTV----------------------------------KSTLDCHVKT 1216
GEKPY+C ECGK+F + H KT
Sbjct: 470 GEKPYECKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKT 529
Query: 1217 HTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKP 1276
HTG+K + C+ C AF SL+ H R HTG KP++C C FR++ + H + H
Sbjct: 530 HTGEKPYECNQCGKAFRCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMHERTHTGE 589
Query: 1277 DPKKARK 1283
P + ++
Sbjct: 590 KPYECKQ 596
Score = 122 bits (307), Expect = 2e-27
Identities = 57/144 (39%), Positives = 89/144 (61%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AF SA+ L H + H E+ + C C KAF A++L++H +TH
Sbjct: 562 KPYECKQCGKAFRSASHLRMHER-THTGEKPYECKQCGKAFSCASNLRKHGRTH------ 614
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C KAF S L+ H R HTGE+P+ C CEKAF + S+ Q+H +KH G
Sbjct: 615 TGEKP--YECKQCGKAFRSASNLQMHERTHTGEKPYECKECEKAFCKFSSFQIHERKHRG 672
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY+C +C GFT +++H +
Sbjct: 673 EKPYECKHCGNGFTSAKILQIHAR 696
Score = 119 bits (297), Expect = 4e-26
Identities = 55/145 (37%), Positives = 86/145 (59%), Gaps = 9/145 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AF L +H + H E+ + C C KAF+ A+HL+ H +TH
Sbjct: 534 KPYECNQCGKAFRCCNSLRYHER-THTGEKPYECKQCGKAFRSASHLRMHERTH------ 586
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C KAF+ S L +H R HTGE+P+ C C KAF S LQ+H + HTG
Sbjct: 587 TGEKP--YECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTG 644
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKR 1799
E+PY+C C F + S+ ++H ++
Sbjct: 645 EKPYECKECEKAFCKFSSFQIHERK 669
Score = 114 bits (284), Expect = 1e-24
Identities = 57/163 (34%), Positives = 88/163 (53%), Gaps = 10/163 (6%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
V G G +P ++C EC +AF S + L H + H E+ + C C KAF+
Sbjct: 435 VHGGTHTGEKP------YECKECGKAFRSTSHLRVHGR-THTGEKPYECKECGKAFRYVK 487
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
HL+ H +T + S ++P +KC CEK F + H + HTGE+P+ C C KAF
Sbjct: 488 HLQIHERTEKHIRMPSGERP--YKCSICEKGFYSAKSFQTHEKTHTGEKPYECNQCGKAF 545
Query: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
++L+ H + HTGE+PY+C C F S++++H +R H+
Sbjct: 546 RCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMH-ERTHT 587
Score = 107 bits (266), Expect = 1e-22
Identities = 51/144 (35%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AFS A+ L H + H E+ + C C KAF+ A++L+ H +TH
Sbjct: 590 KPYECKQCGKAFSCASNLRKHGR-THTGEKPYECKQCGKAFRSASNLQMHERTH------ 642
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C CEKAF K S + H R H GE+P+ C C F LQ+H + H G
Sbjct: 643 TGEKP--YECKECEKAFCKFSSFQIHERKHRGEKPYECKHCGNGFTSAKILQIHARTHIG 700
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+ Y+C C F S++ +H +
Sbjct: 701 EKHYECKECGKAFNYFSSLHIHAR 724
Score = 105 bits (263), Expect = 3e-22
Identities = 45/118 (38%), Positives = 64/118 (54%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
+ + + Y C C K F +S+L++H R+HTGEKPY+CK CG+ F S+ L+ HE+
Sbjct: 581 MHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHER 640
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
THTG K + C C +F S H H KPY+C C GF + + H + H
Sbjct: 641 THTGEKPYECKECEKAFCKFSSFQIHERKHRGEKPYECKHCGNGFTSAKILQIHARTH 698
Score = 104 bits (260), Expect = 7e-22
Identities = 54/158 (34%), Positives = 75/158 (47%)
Query: 1126 IRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRH 1185
IR QE EK K I ++ + C +C K+F S + H
Sbjct: 181 IRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCGKAFHSFSLYLIH 240
Query: 1186 VRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLH 1245
R HTGEKPY+C +CGKSFT +TL H +THTG+K + C C AF + S H R H
Sbjct: 241 ERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSH 300
Query: 1246 TGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
G KP++C C F + + H + H P + ++
Sbjct: 301 MGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQ 338
Score = 103 bits (256), Expect = 2e-21
Identities = 52/142 (36%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
R ++C C + F SA H K H E+ + C C KAF ++ + H + H
Sbjct: 360 RPYKCKICGKGFYSAKSFQTHEK-THTGEKRYKCKQCGKAFNLSSSFRYHERIH------ 412
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C KAF SQL H HTGE+P+ C C KAF S L+VH + HTG
Sbjct: 413 TGEKP--YECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFRSTSHLRVHGRTHTG 470
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PY+C C F ++++H
Sbjct: 471 EKPYECKECGKAFRYVKHLQIH 492
Score = 101 bits (251), Expect = 8e-21
Identities = 54/169 (31%), Positives = 76/169 (44%), Gaps = 35/169 (20%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGR---------------------------ERIHG 1687
+ +QC EC +AF+ + L H + G+ ER +
Sbjct: 304 KPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSGERPYK 363
Query: 1688 CPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGE 1747
C +C K F A + H +TH + +KC C KAF S H RIHTGE
Sbjct: 364 CKICGKGFYSAKSFQTHEKTHTG--------EKRYKCKQCGKAFNLSSSFRYHERIHTGE 415
Query: 1748 RPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+P+ C C KAF S L+VH HTGE+PY+C C F S++++H
Sbjct: 416 KPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFRSTSHLRVH 464
Score = 96.7 bits (239), Expect = 2e-19
Identities = 46/144 (31%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C ++F+ +A L H + H E+ + C C KAF ++ H ++H
Sbjct: 248 KPYECKQCGKSFTYSATLQIHER-THTGEKPYECSKCDKAFHSSSSYHRHERSHMG---- 302
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP ++C C KAFA S L RH R H+G++P+ C + + + Q H++ ++G
Sbjct: 303 --EKP--YQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSG 358
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
ERPYKC C GF + + H K
Sbjct: 359 ERPYKCKICGKGFYSAKSFQTHEK 382
Score = 95.1 bits (235), Expect = 6e-19
Identities = 54/183 (29%), Positives = 91/183 (49%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C C + F + + H +H + + C C KAF + H +TH
Sbjct: 192 KPYACKVCGKTFIFHSSIRRHMV-MHSGDGTYKCKFCGKAFHSFSLYLIHERTH------ 244
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C K+F + L+ H R HTGE+P+ C+ C+KAF+ S+ H + H G
Sbjct: 245 TGEKP--YECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSHMG 302
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+PY+C C F S+++ H +R HS + +Q GE LS + + ++
Sbjct: 303 EKPYQCKECGKAFAYTSSLRRH-ERTHS-----GKKPYECKQYGEGLSYLISFQTHIRMN 356
Query: 1835 AGE 1837
+GE
Sbjct: 357 SGE 359
Score = 89.4 bits (220), Expect = 3e-17
Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 9/122 (7%)
Query: 1680 HGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLER 1739
H E+ + C VC K F + ++ HM H + +KC C KAF S
Sbjct: 188 HTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDGT--------YKCKFCGKAFHSFSLYLI 239
Query: 1740 HSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKR 1799
H R HTGE+P+ C C K+F + LQ+H + HTGE+PY+C+ C F S+ H +R
Sbjct: 240 HERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRH-ER 298
Query: 1800 AH 1801
+H
Sbjct: 299 SH 300
Score = 81.6 bits (200), Expect = 6e-15
Identities = 38/110 (34%), Positives = 54/110 (49%)
Query: 1174 KSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFS 1233
K+F+ + R HTGEKPY C CGK+F S++ H+ H+G + C C AF
Sbjct: 173 KAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCGKAFH 232
Query: 1234 TKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
+ +H R HTG KP++C C F S + H + H P + K
Sbjct: 233 SFSLYLIHERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKPYECSK 282
Score = 68.6 bits (166), Expect = 6e-11
Identities = 27/78 (34%), Positives = 42/78 (53%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
+ + + + + Y C +C GF + L+ H R+H GEK Y+CK CG+ F L H +
Sbjct: 665 IHERKHRGEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNYFSSLHIHAR 724
Query: 1016 THTGVKAFSCSVCNASFT 1033
TH G K + C C +F+
Sbjct: 725 THMGEKPYECKDCGKAFS 742
Score = 64.7 bits (156), Expect = 8e-10
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
+ NL + + ++C EC++AF + H ++ H E+ + C C F A
Sbjct: 632 ASNLQMHERTHTGEKPYECKECEKAFCKFSSFQIHERK-HRGEKPYECKHCGNGFTSAKI 690
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L+ H +TH + ++C C KAF S L H+R H GE+P+ C C KAF+
Sbjct: 691 LQIHARTHIG--------EKHYECKECGKAFNYFSSLHIHARTHMGEKPYECKDCGKAFS 742
Score = 59.7 bits (143), Expect = 3e-08
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 1719 PRVFKCDTCE--KAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGER 1776
P+ +KC + KAF + R HTGE+P+ C +C K F S+++ HM H+G+
Sbjct: 161 PKPYKCQQPKNKKAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDG 220
Query: 1777 PYKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC +C F S +H +R H+
Sbjct: 221 TYKCKFCGKAFHSFSLYLIH-ERTHT 245
>gi|38570117 zinc finger protein 569 [Homo sapiens]
Length = 686
Score = 245 bits (625), Expect = 3e-64
Identities = 161/537 (29%), Positives = 231/537 (43%), Gaps = 50/537 (9%)
Query: 65 PHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLIC 123
P +C+ C + FN +L H H+GE P C C K FS L H +H +E++ C
Sbjct: 185 PFKCNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQSYKC 244
Query: 124 SECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSST 183
+ECG F S L H H G + +ACK C+K F S L +H K H +
Sbjct: 245 NECGKAFIKMSNLIRHQRIH----TGEKPYACKECEKSFSQKSNLIDHEKIHTGEK---- 296
Query: 184 RSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTH 243
Y C CGK F + L H ++HTGE+P+ C+ECGKAF + +L H
Sbjct: 297 ------------PYECNECGKAFSQKQSLIAHQKVHTGEKPYACNECGKAFPRIASLALH 344
Query: 244 MIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
M HTGEKP+ C C AFSQ L HV R+H+ K Y C EC F +L H
Sbjct: 345 MRSHTGEKPYKCDKCGKAFSQFSMLIIHV-RIHTGEK---PYECNECGKAFSQSSALTVH 400
Query: 304 ISKMHMGGPQNSTSSTETA--HVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQL 361
+ + H G A H Q + ++ + Q+
Sbjct: 401 M-RSHTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYECNECGK---------AFIQM 450
Query: 362 LELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPA-------AAHPNDS 414
L + +G+ P ++ +++ +SG + N
Sbjct: 451 SNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFI 510
Query: 415 CHAKTSA---PHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPG 471
H K P+ N + ++ T + E P + DK K + L
Sbjct: 511 THQKVHTGEKPYDCN-ECGKAFSQIASLTLHLRSHTGEKPYECDKCGKAF--SQCSLLNL 567
Query: 472 SIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKT 531
+R G + +VC C K F + + L+ H+R HT EKP++C +C +AF+ S+LT HI+
Sbjct: 568 HMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRG 627
Query: 532 HTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
HTG K F C C K+FS SL +H+R HTG +P+ C C K F H H H
Sbjct: 628 HTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQKSHLVRHQRIH 684
Score = 236 bits (603), Expect = 1e-61
Identities = 171/612 (27%), Positives = 267/612 (43%), Gaps = 71/612 (11%)
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFT-YSCPHCGKTFQKPSQLTR 214
K + F+ + +K M+ + +SY + T + C HCGK F + L R
Sbjct: 144 KCLEHNFDCHNNVKCLMRKEHCEYNEPVKSYGNSSSHFVITPFKCNHCGKGFNQTLDLIR 203
Query: 215 HIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQR 274
H+RIHTGE+P++CS C KAF+ K L H H+ E+ + C C AF + NL H QR
Sbjct: 204 HLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQSYKCNECGKAFIKMSNLIRH-QR 262
Query: 275 VHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLP 334
+H+ K Y C EC F +L H K+H G + A +L
Sbjct: 263 IHTGEK---PYACKECEKSFSQKSNLIDH-EKIHTGEKPYECNECGKAFSQKQSLIAHQK 318
Query: 335 LQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQ 394
+ E + ++ + + + P + + + Q S+ + I+ I
Sbjct: 319 VHTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLI-IHVRI-- 375
Query: 395 QALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
++G + + C S A + S + E+ P + ++ ++ S +K
Sbjct: 376 ----HTG-----EKPYECNECGKAFSQSSALTVHMRSHTGEK--PYECKECRKAFSHKKN 424
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+K+ ++ P+ C C K F + S+LVRH RIHT EKP+ C +
Sbjct: 425 FITHQKIHTREKPY--------------ECNECGKAFIQMSNLVRHQRIHTGEKPYICKE 470
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +AF+ KS L AH K H+G K ++C C K+FS + H ++HTG +P+ C C K
Sbjct: 471 CGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKA 530
Query: 575 FRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQ 633
F H+ SH KP + + GK + L+
Sbjct: 531 FSQIASLTLHLRSHTGE----------KPYECDKCGKA--------------FSQCSLL- 565
Query: 634 PIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG 693
N +S+ ++PY C C +A+ + L H+R HTGEKP++C++CG+
Sbjct: 566 ----NLHMRSH-------TGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKA 614
Query: 694 FVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTS 753
F + L HIR HTG K F C C AF+ SL HM H +PY C C K F
Sbjct: 615 FSQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQK 674
Query: 754 LNCKKHMKTHRY 765
+ +H + H +
Sbjct: 675 SHLVRHQRIHTH 686
Score = 213 bits (542), Expect = 1e-54
Identities = 147/509 (28%), Positives = 230/509 (45%), Gaps = 49/509 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
++C C +F + + +H + H R ++ ++C++C + F NL H+ H+GE P C
Sbjct: 214 YECSNCRKAFSHKEKLIKHYKIHSR-EQSYKCNECGKAFIKMSNLIRHQRIHTGEKPYAC 272
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS+ ++L H +H E+ C+ECG F+ + L H + H G + +AC
Sbjct: 273 KECEKSFSQKSNLIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKVH----TGEKPYAC 328
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
C K F + L HM++H + Y C CGK F + S L H
Sbjct: 329 NECGKAFPRIASLALHMRSHTGEK----------------PYKCDKCGKAFSQFSMLIIH 372
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
+RIHTGE+P++C+ECGKAF+Q AL HM HTGEKP+ C C AFS K N +H Q++
Sbjct: 373 VRIHTGEKPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITH-QKI 431
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
H+ K Y C EC F + +L H ++H G A + L +
Sbjct: 432 HTREK---PYECNECGKAFIQMSNLVRH-QRIHTGEKPYICKECGKAFSQKSNLIAHEKI 487
Query: 336 QQTE-AQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQL-SITVGINQ--- 390
E + + SQ + + Q + E P + + + Q+ S+T+ +
Sbjct: 488 HSGEKPYECNECGKAFSQKQNFITHQKVHTGE-KPYDCNECGKAFSQIASLTLHLRSHTG 546
Query: 391 ------DILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQ 444
D +A L ++ +H + P+ N + +++T +
Sbjct: 547 EKPYECDKCGKAFSQCSLLNLHMRSHTGEK-------PYVCN-ECGKAFSQRTSLIVHMR 598
Query: 445 EKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIH 504
E P + +K K + S L IR G + C C K F + S L H+R H
Sbjct: 599 GHTGEKPYECNKCGKAFSQSSS--LTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKH 656
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
T EKP+ C +C +AF+ KS L H + HT
Sbjct: 657 TGEKPYHCIECGKAFSQKSHLVRHQRIHT 685
Score = 196 bits (499), Expect = 1e-49
Identities = 112/333 (33%), Positives = 166/333 (49%), Gaps = 15/333 (4%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F + + L H+RSHTGEKPYKC CG+ F +L H + HTG K +
Sbjct: 324 KPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRIHTGEKPYE 383
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F+ + +LT HM +H KPY+C C + F KK+ HQ + +
Sbjct: 384 CNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSH----KKNFITHQKIHTREKPYE 439
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G ++ + +P + + +Q + + E EK +
Sbjct: 440 CNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNEC 499
Query: 1145 EKDRISELRDKQAELQDEPKHAN----CCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
K KQ + + H C C K+F + + L H+R HTGEKPY+CD+C
Sbjct: 500 GK----AFSQKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLHLRSHTGEKPYECDKC 555
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GK+F+ S L+ H+++HTG+K + C+ C AFS + SL VHMR HTG KP++C C F
Sbjct: 556 GKAFSQCSLLNLHMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAF 615
Query: 1261 RTSGRRKTHMQFH--YKP-DPKKARKPMTRSSS 1290
S H++ H KP D K K ++ SS
Sbjct: 616 SQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISS 648
Score = 186 bits (473), Expect = 1e-46
Identities = 139/543 (25%), Positives = 227/543 (41%), Gaps = 81/543 (14%)
Query: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYC 543
C +C K F + DL+RH+RIHT EKP++C C +AF+ K L H K H+ +++KC C
Sbjct: 188 CNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQSYKCNEC 247
Query: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKP 603
K+F +L H R+HTG +P+AC C+K F +K+++ H
Sbjct: 248 GKAFIKMSNLIRHQRIHTGEKPYACKECEKSF----SQKSNLIDH--------------- 288
Query: 604 AKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCH 663
K+ G ++P + G QS + V+ ++PY C C
Sbjct: 289 EKIHTG-----------EKPYECNECG-----KAFSQKQSLIAHQKVHTGEKPYACNECG 332
Query: 664 RAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFT 723
+A+ + L H+RSHTGEKP+KC +CG+ F +L H+R HTG K ++C C AF+
Sbjct: 333 KAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRIHTGEKPYECNECGKAFS 392
Query: 724 TGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQ------------- 770
+L HM H +PY C C+K F N H K H E +
Sbjct: 393 QSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYECNECGKAFIQMSN 452
Query: 771 LQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGT 830
L +HQ+ + + + ++ +A +Q I +++ + N + Q+ +
Sbjct: 453 LVRHQRIHTGEKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITH 512
Query: 831 EEAGLGQQLADQPLEADEDGFVAPQDP-----LRGHV-DQFEEQSPAQQSFEPAGLPQGF 884
++ G ++P + +E G Q LR H ++ E ++F L
Sbjct: 513 QKVHTG----EKPYDCNECGKAFSQIASLTLHLRSHTGEKPYECDKCGKAFSQCSLLNLH 568
Query: 885 TVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQ----------SLLQAPSSDGMNVT 934
+ T ++P + SQ S H + + S ++T
Sbjct: 569 MRSHT-GEKPYV-----CNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLT 622
Query: 935 TRLIQESSQEELDLQAQGSQF-------LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVR 987
+ + ++ D G F L + + Y C C K F + SHL +H R
Sbjct: 623 IHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQKSHLVRHQR 682
Query: 988 SHT 990
HT
Sbjct: 683 IHT 685
Score = 184 bits (468), Expect = 5e-46
Identities = 101/311 (32%), Positives = 148/311 (47%), Gaps = 8/311 (2%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F +SS L H+RSHTGEKPY+CK C + F +H+K HT K +
Sbjct: 380 KPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYE 439
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C+ C +F +L RH H KPY C C + F K ++ H+ + S
Sbjct: 440 CNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQ----KSNLIAHEKIHSGEKPYE 495
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G +++ + + +P + +Q+A + + EK
Sbjct: 496 CNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLHLRSHTGEKPYECDKC 555
Query: 1145 EK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + S L E + C C K+F + + L+ H+R HTGEKPY+C++CGK
Sbjct: 556 GKAFSQCSLLNLHMRSHTGEKPYV--CNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGK 613
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
+F+ S+L H++ HTG+K F C C AFS SL +HMR HTG KP+ C C F
Sbjct: 614 AFSQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQ 673
Query: 1263 SGRRKTHMQFH 1273
H + H
Sbjct: 674 KSHLVRHQRIH 684
Score = 179 bits (455), Expect = 2e-44
Identities = 107/356 (30%), Positives = 171/356 (48%), Gaps = 23/356 (6%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P + EK +K + L + G + + C C K F + L+ H ++HT EK
Sbjct: 267 EKPYACKECEKSFSQKSN--LIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKVHTGEK 324
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+ C +C +AF ++L H+++HTG K +KC C K+FS L +H+R+HTG +P+ C
Sbjct: 325 PYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRIHTGEKPYEC 384
Query: 569 PHCDKKFRTSGHRKTHIASH-----FKHTELRK--------MRHQR-----KPAKV-RVG 609
C K F S H+ SH ++ E RK + HQ+ KP + G
Sbjct: 385 NECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYECNECG 444
Query: 610 KTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ--SYFNNNFVNEADRPYKCFYCHRAYK 667
K I + ++ + I + I F Q + + ++ ++PY+C C +A+
Sbjct: 445 KAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFS 504
Query: 668 KSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGS 727
+ + H + HTGEKP+ C++CG+ F L H+R+HTG K ++C C AF+
Sbjct: 505 QKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLHLRSHTGEKPYECDKCGKAFSQCSL 564
Query: 728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDS 783
L HM H +PY+C C K F + HM+ H E + + +A S S
Sbjct: 565 LNLHMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSS 620
Score = 167 bits (423), Expect = 9e-41
Identities = 140/557 (25%), Positives = 223/557 (40%), Gaps = 66/557 (11%)
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTF----KTSLNCKKHMK 761
+H + FKC C F L RH+ IH +PY C C+K F K + K H +
Sbjct: 179 SHFVITPFKCNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSR 238
Query: 762 THRYELAQ---------QLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVV 812
Y+ + L +HQ+ + + ++ ++ +Q I+ +++ +
Sbjct: 239 EQSYKCNECGKAFIKMSNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKPY 298
Query: 813 AANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQ-DPLRGHVDQFEEQSPA 871
N + Q ++ ++ G++ P +E G P+ L H+ + P
Sbjct: 299 ECNECGKAFSQKQSLIAHQKVHTGEK----PYACNECGKAFPRIASLALHMRSHTGEKPY 354
Query: 872 QQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGM 931
+ Q F++ + V+ E +F Q S L M
Sbjct: 355 KCDKCGKAFSQ-FSMLIIH--------VRIHTGEKPYECNECGKAFSQSSALTVH----M 401
Query: 932 NVTTRLIQESSQEELDLQAQGSQFLEDNEDQSR-RSYRCDYCNKGFKKSSHLKQHVRSHT 990
T +E + F+ + +R + Y C+ C K F + S+L +H R HT
Sbjct: 402 RSHTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYECNECGKAFIQMSNLVRHQRIHT 461
Query: 991 GEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKP 1050
GEKPY CK CG+ F L +HEK H+G K + C+ C +F+ + H H KP
Sbjct: 462 GEKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKP 521
Query: 1051 YKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNASRKSR 1109
Y C C + F H++ H TGE D C + + S N +S
Sbjct: 522 YDCNECGKAFSQIASLTLHLRSH---------TGEKPYECDKCGKAFSQCSLLNLHMRSH 572
Query: 1110 PEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCC 1169
+ E + A R S + + ++P C
Sbjct: 573 TGEKPYVCNECGK---------------------AFSQRTSLIVHMRGHTGEKPYE---C 608
Query: 1170 TYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCS 1229
C K+F + S L H+R HTGEKP+ C +CGK+F+ S+L H++ HTG+K + C C
Sbjct: 609 NKCGKAFSQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECG 668
Query: 1230 NAFSTKGSLKVHMRLHT 1246
AFS K L H R+HT
Sbjct: 669 KAFSQKSHLVRHQRIHT 685
Score = 158 bits (400), Expect = 4e-38
Identities = 99/320 (30%), Positives = 139/320 (43%), Gaps = 49/320 (15%)
Query: 965 RSYRCDYCN--KGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
R C+Y K + SS SH P+KC CG+GF + L H + HTG K
Sbjct: 161 RKEHCEYNEPVKSYGNSS-------SHFVITPFKCNHCGKGFNQTLDLIRHLRIHTGEKP 213
Query: 1023 FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSA 1082
+ CS C +F+ L +H H + YKC C + F + +H + H
Sbjct: 214 YECSNCRKAFSHKEKLIKHYKIHSREQSYKCNECGKAFIKMSNLIRHQRIH--------- 264
Query: 1083 TGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQS 1142
TGE +P E+ +Q + + E EK +
Sbjct: 265 TGE-----------------------KPYACKECEKSFSQKSNLIDHEKIHTGEKPYECN 301
Query: 1143 AAEKDRISELRDKQAELQDEPKHAN----CCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
K KQ+ + + H C C K+F + + L H+R HTGEKPYKCD
Sbjct: 302 ECGK----AFSQKQSLIAHQKVHTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCD 357
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
+CGK+F+ S L HV+ HTG+K + C+ C AFS +L VHMR HTG KP++C C
Sbjct: 358 KCGKAFSQFSMLIIHVRIHTGEKPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRK 417
Query: 1259 RFRTSGRRKTHMQFHYKPDP 1278
F TH + H + P
Sbjct: 418 AFSHKKNFITHQKIHTREKP 437
Score = 135 bits (340), Expect = 4e-31
Identities = 84/303 (27%), Positives = 137/303 (45%), Gaps = 39/303 (12%)
Query: 490 EFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFST 549
E+ +P + H PFKC C + F L H++ HTG K ++C C K+FS
Sbjct: 166 EYNEPVKSYGNSSSHFVITPFKCNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSH 225
Query: 550 SGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVG 609
L H ++H+ + + C C K F K + L +RHQR + G
Sbjct: 226 KEKLIKHYKIHSREQSYKCNECGKAF-------------IKMSNL--IRHQR----IHTG 266
Query: 610 KTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ--SYFNNNFVNEADRPYKCFYCHRAYK 667
++P + + F Q + ++ ++ ++PY+C C +A+
Sbjct: 267 -----------EKPYACKEC-------EKSFSQKSNLIDHEKIHTGEKPYECNECGKAFS 308
Query: 668 KSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGS 727
+ L H + HTGEKP+ C++CG+ F L H+R+HTG K +KC C AF+
Sbjct: 309 QKQSLIAHQKVHTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSM 368
Query: 728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQ 787
L H+ IH +PY C C K F S HM++H E + ++ ++A S + +
Sbjct: 369 LIIHVRIHTGEKPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITH 428
Query: 788 QSM 790
Q +
Sbjct: 429 QKI 431
Score = 132 bits (331), Expect = 4e-30
Identities = 72/170 (42%), Positives = 96/170 (56%), Gaps = 10/170 (5%)
Query: 1629 ACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGC 1688
AC+E + S NL + + ++C EC +AFS L+ H K VH E+ + C
Sbjct: 271 ACKECEKSFSQKS-NLIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQK-VHTGEKPYAC 328
Query: 1689 PVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER 1748
C KAF R L HM++H + +KP +KCD C KAF++ S L H RIHTGE+
Sbjct: 329 NECGKAFPRIASLALHMRSH------TGEKP--YKCDKCGKAFSQFSMLIIHVRIHTGEK 380
Query: 1749 PFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
P+ C C KAF+Q SAL VHM+ HTGE+PY+C C F+ K N H K
Sbjct: 381 PYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITHQK 430
Score = 122 bits (307), Expect = 2e-27
Identities = 79/264 (29%), Positives = 124/264 (46%), Gaps = 32/264 (12%)
Query: 1043 ATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDR 1102
++H + P+KC C +GF T+ +H++ H TGE + +
Sbjct: 178 SSHFVITPFKCNHCGKGFNQTLDLIRHLRIH---------TGE------------KPYEC 216
Query: 1103 NASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDE 1162
+ RK+ F+ +E +L K S S K A + +R ++ ++
Sbjct: 217 SNCRKA------FSHKE--KLIKHYKIHSREQSYKCNECGKAFIKMSNLIRHQRIHTGEK 268
Query: 1163 PKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKL 1222
P C C KSF + S+L+ H +IHTGEKPY+C+ECGK+F+ K +L H K HTG+K
Sbjct: 269 PY---ACKECEKSFSQKSNLIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKVHTGEKP 325
Query: 1223 FSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKAR 1282
++C+ C AF SL +HMR HTG KP+KC C F H++ H P +
Sbjct: 326 YACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRIHTGEKPYECN 385
Query: 1283 KPMTRSSSEGLQPVNLLNSSSTDP 1306
+ S V++ + + P
Sbjct: 386 ECGKAFSQSSALTVHMRSHTGEKP 409
Score = 121 bits (304), Expect = 5e-27
Identities = 62/149 (41%), Positives = 94/149 (63%), Gaps = 10/149 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AFS ++L H + H E+ + C C KAF + T L HM+ H
Sbjct: 548 KPYECDKCGKAFSQCSLLNLHMRS-HTGEKPYVCNECGKAFSQRTSLIVHMRGH------ 600
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C+ C KAF++ S L H R HTGE+PF C+ C KAF+Q S+L +HM+KHTG
Sbjct: 601 TGEKP--YECNKCGKAFSQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTG 658
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSY 1803
E+PY C C F+QKS++ H +R H++
Sbjct: 659 EKPYHCIECGKAFSQKSHLVRH-QRIHTH 686
Score = 119 bits (299), Expect = 2e-26
Identities = 60/144 (41%), Positives = 84/144 (58%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS ++ L H + H E+ + C CRKAF + H + H
Sbjct: 380 KPYECNECGKAFSQSSALTVHMRS-HTGEKPYECKECRKAFSHKKNFITHQKIH------ 432
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C+ C KAF + S L RH RIHTGE+P+ C C KAF+QKS L H K H+G
Sbjct: 433 TREKP--YECNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAHEKIHSG 490
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY+C C F+QK N H K
Sbjct: 491 EKPYECNECGKAFSQKQNFITHQK 514
Score = 119 bits (298), Expect = 3e-26
Identities = 59/148 (39%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C +AFS L+ H K +H RE+ + C C KAF + ++L H + H
Sbjct: 212 KPYECSNCRKAFSHKEKLIKHYK-IHSREQSYKCNECGKAFIKMSNLIRHQRIH------ 264
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C CEK+F++ S L H +IHTGE+P+ C C KAF+QK +L H K HTG
Sbjct: 265 TGEKP--YACKECEKSFSQKSNLIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKVHTG 322
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C C F + +++ LHM R+H+
Sbjct: 323 EKPYACNECGKAFPRIASLALHM-RSHT 349
Score = 118 bits (296), Expect = 5e-26
Identities = 65/173 (37%), Positives = 100/173 (57%), Gaps = 15/173 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AFS A L H + H E+ + C C KAF + + L HM++H
Sbjct: 520 KPYDCNECGKAFSQIASLTLHLRS-HTGEKPYECDKCGKAFSQCSLLNLHMRSH------ 572
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP V C+ C KAF++ + L H R HTGE+P+ C C KAF+Q S+L +H++ HTG
Sbjct: 573 TGEKPYV--CNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRGHTG 630
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
E+P+ C+ C F+Q S++ LHM++ + G E H + G+ S+ HL
Sbjct: 631 EKPFDCSKCGKAFSQISSLTLHMRK---HTG---EKPYHCIECGKAFSQKSHL 677
Score = 117 bits (293), Expect = 1e-25
Identities = 59/141 (41%), Positives = 80/141 (56%), Gaps = 9/141 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C C + F+ L+ H + +H E+ + C CRKAF L +H + H S
Sbjct: 187 KCNHCGKGFNQTLDLIRHLR-IHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQS---- 241
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
+KC+ C KAF K S L RH RIHTGE+P+ C CEK+F+QKS L H K HTGE+P
Sbjct: 242 ----YKCNECGKAFIKMSNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKP 297
Query: 1778 YKCAYCVMGFTQKSNMKLHMK 1798
Y+C C F+QK ++ H K
Sbjct: 298 YECNECGKAFSQKQSLIAHQK 318
Score = 115 bits (287), Expect = 5e-25
Identities = 55/140 (39%), Positives = 84/140 (60%), Gaps = 9/140 (6%)
Query: 1659 CLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQK 1718
C EC +AFS + L+ H K +H E+ + C C KAF + + H + H + +K
Sbjct: 468 CKECGKAFSQKSNLIAHEK-IHSGEKPYECNECGKAFSQKQNFITHQKVH------TGEK 520
Query: 1719 PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPY 1778
P + C+ C KAF++ + L H R HTGE+P+ C C KAF+Q S L +HM+ HTGE+PY
Sbjct: 521 P--YDCNECGKAFSQIASLTLHLRSHTGEKPYECDKCGKAFSQCSLLNLHMRSHTGEKPY 578
Query: 1779 KCAYCVMGFTQKSNMKLHMK 1798
C C F+Q++++ +HM+
Sbjct: 579 VCNECGKAFSQRTSLIVHMR 598
Score = 80.1 bits (196), Expect = 2e-14
Identities = 41/106 (38%), Positives = 54/106 (50%)
Query: 1693 KAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHC 1752
K R H + + G S S FKC+ C K F + L RH RIHTGE+P+ C
Sbjct: 157 KCLMRKEHCEYNEPVKSYGNSSSHFVITPFKCNHCGKGFNQTLDLIRHLRIHTGEKPYEC 216
Query: 1753 TLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C KAF+ K L H K H+ E+ YKC C F + SN+ H +
Sbjct: 217 SNCRKAFSHKEKLIKHYKIHSREQSYKCNECGKAFIKMSNLIRHQR 262
Score = 73.2 bits (178), Expect = 2e-12
Identities = 48/168 (28%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 638 NQFFQSYFNNNFVNEADRPYKC----FYCHRAYK-----KSCHLKQHIRSHTGEK----- 683
+ FF S N + E D KC F CH K + C + ++S+
Sbjct: 127 SDFFPSRHN---LYEYDLFGKCLEHNFDCHNNVKCLMRKEHCEYNEPVKSYGNSSSHFVI 183
Query: 684 -PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYM 742
PFKC+ CG+GF L H+R HTG K ++C C AF+ L +H IH+ + Y
Sbjct: 184 TPFKCNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQSYK 243
Query: 743 CPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSM 790
C C K F N +H + H E ++ +++ S + +D + +
Sbjct: 244 CNECGKAFIKMSNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKI 291
>gi|32698886 zinc finger protein 595 [Homo sapiens]
Length = 648
Score = 242 bits (618), Expect = 2e-63
Identities = 166/554 (29%), Positives = 238/554 (42%), Gaps = 60/554 (10%)
Query: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCP 96
+C C+ F K S +H H +KP +C +C ++F + +LT H H+GE P C
Sbjct: 146 QCNTCVKVFSKFSNSNKHKIRHT-GEKPFKCTECGRSFYMS-HLTQHTGIHAGEKPYKCE 203
Query: 97 VCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK 156
C K F+R SL H +H E+ C ECG F + L EH++ G + + C+
Sbjct: 204 KCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVL----NEHKKIHTGEKPYKCE 259
Query: 157 ACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHI 216
C K F S+ L EH K H + Y C CGK F+ + L H
Sbjct: 260 ECGKAFTRSTTLNEHKKIHTGEK----------------PYKCKECGKAFRWSTSLNEHK 303
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
IHTGE+P+KC ECGKAF Q +L H HTGEKP+ C C AF+Q +L H + +H
Sbjct: 304 NIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIH-RSIH 362
Query: 277 SEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQ 336
SE K Y C EC F SLN H ++H G + A ++ L + +
Sbjct: 363 SEQK---LYKCEECGKAFTWSSSLNKH-KRIHTGEKPYTCEECGKAFYRSSHLAKHKRIH 418
Query: 337 QTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQA 396
E T + S +I + SGQ P ++ +A
Sbjct: 419 TGEKPYTCEECGKAFNQSSTLILH-------KRIHSGQKPYKCEECG-----------KA 460
Query: 397 LENSGLSSIPAAAHPNDSCHAKTSAPHA--QNPDVSSVSNEQTDPTDAEQEKEQESPEKL 454
S + H + + A + ++ N T E P K
Sbjct: 461 FTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTG----------EKPYKC 510
Query: 455 DKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514
+ K + + SI E + + C C K F + + L H +IH+ EKP+KC +
Sbjct: 511 KECGKAFNQSSGLIIHRSIHSEQ--KLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKE 568
Query: 515 CFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKK 574
C +A+ + STLT H + HTG K F C+ C K+F+ S SL H +HTG + + C C K
Sbjct: 569 CGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGKA 628
Query: 575 FRTSGHRKTHIASH 588
F H H
Sbjct: 629 FNRPSTLTVHKRIH 642
Score = 225 bits (573), Expect = 4e-58
Identities = 163/571 (28%), Positives = 236/571 (41%), Gaps = 77/571 (13%)
Query: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACA 256
+ C C K F K S +H HTGE+PFKC+ECG++F Q H H GEKP+ C
Sbjct: 145 FQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMSHLTQ-HTGIHAGEKPYKCE 203
Query: 257 FCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNST 316
C AF++ +L H +R+H+ K Y C EC F+ LN H K+H G
Sbjct: 204 KCGKAFNRSTSLSKH-KRIHTGEK---PYTCEECGKAFRRSTVLNEH-KKIHTGEKPYKC 258
Query: 317 SSTETAHVLTATLFQTLPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQS 375
A + TL E + +P + + L+E + +G+
Sbjct: 259 EECGKAFTRSTTL--------NEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEK 310
Query: 376 PQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNE 435
P ++ +A S + H + + A N S + +
Sbjct: 311 PYKCKECG-----------KAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHR 359
Query: 436 QTDPTDAEQEKEQESPEKLDKKEK--KMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRK 493
S +KL K E+ K S L R G + + C C K F +
Sbjct: 360 SI-----------HSEQKLYKCEECGKAFTWSSS-LNKHKRIHTGEKPYTCEECGKAFYR 407
Query: 494 PSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSL 553
S L +H RIHT EKP+ C +C +AF STL H + H+G K +KC+ C K+F+ S +L
Sbjct: 408 SSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTL 467
Query: 554 KVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTN 612
H ++HTG +P+ C C K F S H + + KP K + GK
Sbjct: 468 NEHKKIHTGEKPYKCEECGKAFIWSASLNEH----------KNIHTGEKPYKCKECGKA- 516
Query: 613 IPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHL 672
GLI + ++ + YKC C +A+ +S L
Sbjct: 517 ------------FNQSSGLII-------------HRSIHSEQKLYKCEECGKAFTRSTAL 551
Query: 673 KQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHM 732
+H + H+GEKP+KC +CG+ + + L H R HTG K F C C AF SL +H
Sbjct: 552 NEHKKIHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHK 611
Query: 733 GIHNDLRPYMCPYCQKTFKTSLNCKKHMKTH 763
IH + Y C C K F H + H
Sbjct: 612 IIHTGEKSYKCEECGKAFNRPSTLTVHKRIH 642
Score = 212 bits (539), Expect = 3e-54
Identities = 144/526 (27%), Positives = 220/526 (41%), Gaps = 55/526 (10%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLI 122
K +C+ C + F+ N HK H+GE P C C + F ++ L H +H E+
Sbjct: 143 KIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFY-MSHLTQHTGIHAGEKPYK 201
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182
C +CG F + L+ H H G + + C+ C K F S+ L EH K H +
Sbjct: 202 CEKCGKAFNRSTSLSKHKRIH----TGEKPYTCEECGKAFRRSTVLNEHKKIHTGEK--- 254
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
Y C CGK F + + L H +IHTGE+P+KC ECGKAF +L
Sbjct: 255 -------------PYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNE 301
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
H HTGEKP+ C C AF Q +L H + +H+ K Y C +C F SL
Sbjct: 302 HKNIHTGEKPYKCKECGKAFRQSRSLNEH-KNIHTGEK---PYTCEKCGKAFNQSSSLII 357
Query: 303 HISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLL 362
H S +H A +++L + + E T + +
Sbjct: 358 HRS-IHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYT-------CEECGKAFYRSS 409
Query: 363 ELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAP 422
L++ + +G+ P ++ + ++ +SG P
Sbjct: 410 HLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSG------------------QKP 451
Query: 423 HAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWH 482
+ + + T + ++ E P K ++ K I S L G + +
Sbjct: 452 Y-KCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSAS--LNEHKNIHTGEKPY 508
Query: 483 VCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQY 542
C C K F + S L+ H IH+ +K +KC +C +AF + L H K H+G K +KC+
Sbjct: 509 KCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKE 568
Query: 543 CMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
C K+++ S +L H R+HTG +PF C C K F S H H
Sbjct: 569 CGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIH 614
Score = 211 bits (537), Expect = 5e-54
Identities = 157/556 (28%), Positives = 232/556 (41%), Gaps = 59/556 (10%)
Query: 155 CKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTR 214
C C K F S +H KIR + + + C CG++F S LT+
Sbjct: 147 CNTCVKVFSKFSNSNKH-----KIRHTGEKPFK-----------CTECGRSFYM-SHLTQ 189
Query: 215 HIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQR 274
H IH GE+P+KC +CGKAFN+ +L H HTGEKP+ C C AF + L H ++
Sbjct: 190 HTGIHAGEKPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEH-KK 248
Query: 275 VHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLP 334
+H+ K Y C EC F +LN H K+H G A + +L
Sbjct: 249 IHTGEK---PYKCEECGKAFTRSTTLNEH-KKIHTGEKPYKCKECGKAFRWSTSL----- 299
Query: 335 LQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDIL 393
E + +P + +Q L+E + +G+ P ++
Sbjct: 300 ---NEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCG---------- 346
Query: 394 QQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEK 453
+A S I + H + A SS N+ E+ E K
Sbjct: 347 -KAFNQSSSLIIHRSIHSEQKLYKCEECGKAFT--WSSSLNKHKRIHTGEKPYTCEECGK 403
Query: 454 LDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCP 513
+ + K K R G + + C C K F + S L+ H RIH+ +KP+KC
Sbjct: 404 AFYRSSHLAKHK--------RIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCE 455
Query: 514 QCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDK 573
+C +AF +TL H K HTG K +KC+ C K+F S SL H +HTG +P+ C C K
Sbjct: 456 ECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGK 515
Query: 574 KFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQ 633
F S H + H + +L K K A R N ++P + G
Sbjct: 516 AFNQSSGLIIHRSIHSEQ-KLYKCEECGK-AFTRSTALNEHKKIHSGEKPYKCKECGKAY 573
Query: 634 PIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG 693
+ + + ++ ++P+ C C +A+ S L +H HTGEK +KC +CG+
Sbjct: 574 NLSS-----TLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGKA 628
Query: 694 FVSAGVLKAHIRTHTG 709
F L H R HTG
Sbjct: 629 FNRPSTLTVHKRIHTG 644
Score = 202 bits (514), Expect = 2e-51
Identities = 109/325 (33%), Positives = 153/325 (47%), Gaps = 16/325 (4%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +S+ L +H R HTGEKPY C+ CG+ F S VL H+K HTG K +
Sbjct: 198 KPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYK 257
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +FT + +L H H KPYKC C + FR + +H H TG
Sbjct: 258 CEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIH---------TG 308
Query: 1085 ET-----EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E E G + + +N +P + Q + + S +K+
Sbjct: 309 EKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLY 368
Query: 1140 -VQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
+ + S +K + K C C K+F + S L +H RIHTGEKPY C+
Sbjct: 369 KCEECGKAFTWSSSLNKHKRIHTGEKPYTC-EECGKAFYRSSHLAKHKRIHTGEKPYTCE 427
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+F STL H + H+GQK + C C AF+ +L H ++HTG KP+KC C
Sbjct: 428 ECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGK 487
Query: 1259 RFRTSGRRKTHMQFHYKPDPKKARK 1283
F S H H P K ++
Sbjct: 488 AFIWSASLNEHKNIHTGEKPYKCKE 512
Score = 198 bits (503), Expect = 5e-50
Identities = 116/337 (34%), Positives = 160/337 (47%), Gaps = 23/337 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F++S+ L +H + HTGEKPYKC+ CG+ F S L H+K HTG K +
Sbjct: 226 KPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYK 285
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + SL H H KPYKC C + FR + +H H TG
Sbjct: 286 CKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIH---------TG 336
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQL----AKIRPQESATVSEKVL 1139
E + C + + S R E + EE + + + + EK
Sbjct: 337 EKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPY 396
Query: 1140 VQSAAEKD--RISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYK 1196
K R S L + K+ ++P C C K+F + S L+ H RIH+G+KPYK
Sbjct: 397 TCEECGKAFYRSSHLAKHKRIHTGEKPY---TCEECGKAFNQSSTLILHKRIHSGQKPYK 453
Query: 1197 CDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHC 1256
C+ECGK+FT +TL+ H K HTG+K + C C AF SL H +HTG KP+KC C
Sbjct: 454 CEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKCKEC 513
Query: 1257 ELRFRTSGRRKTHMQFHYKPDPKKAR---KPMTRSSS 1290
F S H H + K K TRS++
Sbjct: 514 GKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTA 550
Score = 188 bits (477), Expect = 5e-47
Identities = 112/351 (31%), Positives = 166/351 (47%), Gaps = 15/351 (4%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P K +K K +S L R G + + C C K FR+ + L H +IHT EK
Sbjct: 197 EKPYKCEKCGKAF--NRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEK 254
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+KC +C +AF +TL H K HTG K +KC+ C K+F S SL H +HTG +P+ C
Sbjct: 255 PYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEKPYKC 314
Query: 569 PHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILIT 627
C K FR S H + + KP + GK + + I
Sbjct: 315 KECGKAFRQSRSLNEH----------KNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSE 364
Query: 628 D-LGLIQPIPKNQFFQSYFNNNF-VNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPF 685
L + K + S N + ++ ++PY C C +A+ +S HL +H R HTGEKP+
Sbjct: 365 QKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPY 424
Query: 686 KCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPY 745
C +CG+ F + L H R H+G K +KC C AFT +L H IH +PY C
Sbjct: 425 TCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEE 484
Query: 746 CQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQM 796
C K F S + +H H E + ++ +A + + +S+ + ++
Sbjct: 485 CGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKL 535
Score = 187 bits (475), Expect = 8e-47
Identities = 138/557 (24%), Positives = 225/557 (40%), Gaps = 75/557 (13%)
Query: 220 TGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEV 279
T + F+C+ C K F++ H I+HTGEKP C C +F SH+ + H+ +
Sbjct: 140 TQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSF-----YMSHLTQ-HTGI 193
Query: 280 KNGPT-YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQT 338
G Y C +C F SL+ H ++H G + A + L
Sbjct: 194 HAGEKPYKCEKCGKAFNRSTSLSKH-KRIHTGEKPYTCEECGKAFRRSTVL--------N 244
Query: 339 EAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
E + +P + + L+E + +G+ P ++ + +
Sbjct: 245 EHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSL----- 299
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
N+ + T + + + + + E P +K
Sbjct: 300 --------------NEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKC 345
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K + S + SI E + + C C K F S L +H RIHT EKP+ C +C +
Sbjct: 346 GKAFNQSSSLIIHRSIHSEQ--KLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGK 403
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577
AF S L H + HTG K + C+ C K+F+ S +L +H R+H+G +P+ C C K F
Sbjct: 404 AFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFT- 462
Query: 578 SGHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIP 636
R T + H +K+ KP K GK I
Sbjct: 463 ---RSTTLNEH------KKIHTGEKPYKCEECGKAFI----------------------- 490
Query: 637 KNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVS 696
+ S + ++ ++PYKC C +A+ +S L H H+ +K +KC +CG+ F
Sbjct: 491 ---WSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTR 547
Query: 697 AGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNC 756
+ L H + H+G K +KC C A+ +L +H IH +P+ C C K F S +
Sbjct: 548 STALNEHKKIHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSL 607
Query: 757 KKHMKTHRYELAQQLQQ 773
KH H E + + ++
Sbjct: 608 TKHKIIHTGEKSYKCEE 624
Score = 186 bits (471), Expect = 2e-46
Identities = 111/322 (34%), Positives = 153/322 (47%), Gaps = 25/322 (7%)
Query: 21 TLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFN 80
TLN + + P +KC+ C +F + H H +KP++C +C + F +
Sbjct: 270 TLNEHKKIHTGEKP--YKCKECGKAFRWSTSLNEHKNIHT-GEKPYKCKECGKAFRQSRS 326
Query: 81 LTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVH 139
L HK H+GE P TC C K F++ +SL H +H +++ C ECG FT S L H
Sbjct: 327 LNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCEECGKAFTWSSSLNKH 386
Query: 140 MEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHY------------KIRVSSTRSYN 187
H G + + C+ C K F SS L +H + H SST +
Sbjct: 387 KRIH----TGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILH 442
Query: 188 RNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKH 247
+ I Y C CGK F + + L H +IHTGE+P+KC ECGKAF +L H H
Sbjct: 443 KRIHSGQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIH 502
Query: 248 TGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKM 307
TGEKP+ C C AF+Q L H + +HSE K Y C EC F +LN H K+
Sbjct: 503 TGEKPYKCKECGKAFNQSSGLIIH-RSIHSEQK---LYKCEECGKAFTRSTALNEH-KKI 557
Query: 308 HMGGPQNSTSSTETAHVLTATL 329
H G A+ L++TL
Sbjct: 558 HSGEKPYKCKECGKAYNLSSTL 579
Score = 184 bits (466), Expect = 9e-46
Identities = 108/306 (35%), Positives = 143/306 (46%), Gaps = 23/306 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + + +H R H +KP+ C++C + F L HK H+GE P C
Sbjct: 200 YKCEKCGKAFNRSTSLSKHKRIH-TGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKC 258
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+R +L H +H E+ C ECG F + L EH+ G + + C
Sbjct: 259 EECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSL----NEHKNIHTGEKPYKC 314
Query: 156 KACKKEFETSSELKEHMKTH------------YKIRVSSTRSYNRNIDRSGFTYSCPHCG 203
K C K F S L EH H SS+ +R+I Y C CG
Sbjct: 315 KECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCEECG 374
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F S L +H RIHTGE+P+ C ECGKAF + L H HTGEKP+ C C AF+
Sbjct: 375 KAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFN 434
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAH 323
Q L H +R+HS K Y C EC F +LN H K+H G A
Sbjct: 435 QSSTLILH-KRIHSGQK---PYKCEECGKAFTRSTTLNEH-KKIHTGEKPYKCEECGKAF 489
Query: 324 VLTATL 329
+ +A+L
Sbjct: 490 IWSASL 495
Score = 181 bits (459), Expect = 6e-45
Identities = 101/315 (32%), Positives = 142/315 (45%), Gaps = 42/315 (13%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ Y+C+ C K F SS L +H R HTGEKPY C+ CG+ F S L H++ HTG K +
Sbjct: 365 QKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPY 424
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSAT 1083
+C C +F + +L H H KPYKC C + F + +H K H T
Sbjct: 425 TCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKKIH---------T 475
Query: 1084 GET-----EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKV 1138
GE E G + + +N +P + + K Q S + +
Sbjct: 476 GEKPYKCEECGKAFIWSASLNEHKNIHTGEKPY-------KCKECGKAFNQSSGLIIHR- 527
Query: 1139 LVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
+ E K C C K+F + + L H +IH+GEKPYKC
Sbjct: 528 -------------------SIHSEQKLYKC-EECGKAFTRSTALNEHKKIHSGEKPYKCK 567
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK++ + STL H + HTG+K F+C C AF+ SL H +HTG K +KC C
Sbjct: 568 ECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGK 627
Query: 1259 RFRTSGRRKTHMQFH 1273
F H + H
Sbjct: 628 AFNRPSTLTVHKRIH 642
Score = 178 bits (452), Expect = 4e-44
Identities = 102/322 (31%), Positives = 143/322 (44%), Gaps = 20/322 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F+ S+ L +H HTGEKPYKCK CG+ F S L H+ HTG K ++
Sbjct: 282 KPYKCKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYT 341
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + SL H + H K YKC C + F + KH + H TG
Sbjct: 342 CEKCGKAFNQSSSLIIHRSIHSEQKLYKCEECGKAFTWSSSLNKHKRIH---------TG 392
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E EE + R++ + T + T + +S+T+ + S
Sbjct: 393 EKP---YTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQ 449
Query: 1145 EKDRISELRDKQAELQDEPKHANC--------CTYCPKSFKKPSDLVRHVRIHTGEKPYK 1196
+ + E +H C C K+F + L H IHTGEKPYK
Sbjct: 450 KPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYK 509
Query: 1197 CDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHC 1256
C ECGK+F S L H H+ QKL+ C C AF+ +L H ++H+G KP+KC C
Sbjct: 510 CKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKEC 569
Query: 1257 ELRFRTSGRRKTHMQFHYKPDP 1278
+ S H + H P
Sbjct: 570 GKAYNLSSTLTKHKRIHTGEKP 591
Score = 176 bits (447), Expect = 1e-43
Identities = 100/287 (34%), Positives = 143/287 (49%), Gaps = 23/287 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F S +H R H +KP+ C++C + F +L HK H+GE P TC
Sbjct: 368 YKCEECGKAFTWSSSLNKHKRIHT-GEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTC 426
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F++ ++L H +H ++ C ECG FT + L EH++ G + + C
Sbjct: 427 EECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTL----NEHKKIHTGEKPYKC 482
Query: 156 KACKKEFETSSELKEHMKTH-----YKIRV-------SSTRSYNRNIDRSGFTYSCPHCG 203
+ C K F S+ L EH H YK + SS +R+I Y C CG
Sbjct: 483 EECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECG 542
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F + + L H +IH+GE+P+KC ECGKA+N L H HTGEKP C C AF+
Sbjct: 543 KAFTRSTALNEHKKIHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFN 602
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
+L H + +H+ K+ Y C EC F +L H ++H G
Sbjct: 603 WSSSLTKH-KIIHTGEKS---YKCEECGKAFNRPSTLTVH-KRIHTG 644
Score = 176 bits (445), Expect = 2e-43
Identities = 95/275 (34%), Positives = 135/275 (49%), Gaps = 27/275 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + + H + H +KP++C +C + F +L HK H+GE P C
Sbjct: 256 YKCEECGKAFTRSTTLNEHKKIHT-GEKPYKCKECGKAFRWSTSLNEHKNIHTGEKPYKC 314
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F + SL H +H E+ C +CG F S L +H H ++ + + C
Sbjct: 315 KECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQ----KLYKC 370
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
+ C K F SS L +H + H + Y+C CGK F + S L +H
Sbjct: 371 EECGKAFTWSSSLNKHKRIHTGEK----------------PYTCEECGKAFYRSSHLAKH 414
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
RIHTGE+P+ C ECGKAFNQ L H H+G+KP+ C C AF++ L H +++
Sbjct: 415 KRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEH-KKI 473
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C EC F SLN H +H G
Sbjct: 474 HTGEK---PYKCEECGKAFIWSASLNEH-KNIHTG 504
Score = 176 bits (445), Expect = 2e-43
Identities = 97/308 (31%), Positives = 146/308 (47%), Gaps = 39/308 (12%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C C K FR+ L H IHT EKP+ C +C +AF S+L H H+ K
Sbjct: 308 GEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKL 367
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKM 597
+KC+ C K+F+ S SL H R+HTG +P+ C C K F +R +H+A H
Sbjct: 368 YKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAF----YRSSHLAKH--------- 414
Query: 598 RHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQS--YFNNNFVNEADR 655
++ G ++P + G F QS + ++ +
Sbjct: 415 ------KRIHTG-----------EKPYTCEECG-------KAFNQSSTLILHKRIHSGQK 450
Query: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
PYKC C +A+ +S L +H + HTGEKP+KC +CG+ F+ + L H HTG K +KC
Sbjct: 451 PYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKC 510
Query: 716 LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQ 775
C AF L H IH++ + Y C C K F S +H K H E + ++
Sbjct: 511 KECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKECG 570
Query: 776 QAASIDDS 783
+A ++ +
Sbjct: 571 KAYNLSST 578
Score = 172 bits (437), Expect = 2e-42
Identities = 104/335 (31%), Positives = 154/335 (45%), Gaps = 24/335 (7%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
++C+ C K F K S+ +H HTGEKP+KC CGR F S L H H G K + C
Sbjct: 145 FQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMSH-LTQHTGIHAGEKPYKCE 203
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F + SL++H H KPY C C + FR + +H K H TGE
Sbjct: 204 KCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIH---------TGEK 254
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEK 1146
EE + R+ + ++ T + + + S +++E + + +
Sbjct: 255 ---PYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEKP 311
Query: 1147 DRISELRDKQAELQDEPKHAN--------CCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
+ E + + +H N C C K+F + S L+ H IH+ +K YKC+
Sbjct: 312 YKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCE 371
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+FT S+L+ H + HTG+K ++C C AF L H R+HTG KP+ C C
Sbjct: 372 ECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGK 431
Query: 1259 RFRTSGRRKTHMQFHYKPDPKKAR---KPMTRSSS 1290
F S H + H P K K TRS++
Sbjct: 432 AFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTT 466
Score = 147 bits (372), Expect = 7e-35
Identities = 83/228 (36%), Positives = 114/228 (50%), Gaps = 18/228 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ CE C +F + S H R H KP++C++C + F L HK H+GE P C
Sbjct: 424 YTCEECGKAFNQSSTLILHKRIHS-GQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKC 482
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F ASL H +H E+ C ECG F S L +H H ++ + + C
Sbjct: 483 EECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQ----KLYKC 538
Query: 156 KACKKEFETSSELKEHMKTH-----YKIR-------VSSTRSYNRNIDRSGFTYSCPHCG 203
+ C K F S+ L EH K H YK + +SST + ++ I ++C CG
Sbjct: 539 EECGKAFTRSTALNEHKKIHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECG 598
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEK 251
K F S LT+H IHTGE+ +KC ECGKAFN+ L H HTG++
Sbjct: 599 KAFNWSSSLTKHKIIHTGEKSYKCEECGKAFNRPSTLTVHKRIHTGKE 646
Score = 145 bits (365), Expect = 5e-34
Identities = 87/266 (32%), Positives = 119/266 (44%), Gaps = 22/266 (8%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F +SSHL +H R HTGEKPY C+ CG+ F S L H++ H+G K +
Sbjct: 394 KPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYK 453
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +FT + +L H H KPYKC C + F + +H H TG
Sbjct: 454 CEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIH---------TG 504
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E C + + S R E + EE + S ++E + S
Sbjct: 505 EKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFT----RSTALNEHKKIHSG 560
Query: 1144 AEKDRISELRDKQAELQDEPKHANC--------CTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
+ + E KH C C K+F S L +H IHTGEK Y
Sbjct: 561 EKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSY 620
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQK 1221
KC+ECGK+F STL H + HTG++
Sbjct: 621 KCEECGKAFNRPSTLTVHKRIHTGKE 646
Score = 142 bits (359), Expect = 2e-33
Identities = 88/292 (30%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 988 SHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMS 1047
S T K ++C C + F H+ HTG K F C+ C SF + LT+H H
Sbjct: 138 STTQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMS-HLTQHTGIHAG 196
Query: 1048 MKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATGETEGGDICMEEEEEHSDRNASR 1106
KPYKC C + F + KH + H P G+ + E ++
Sbjct: 197 EKPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPY 256
Query: 1107 KSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHA 1166
K FT T K + T + + + R S ++ + K
Sbjct: 257 KCEECGKAFTRSTTLNEHK----KIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEKPY 312
Query: 1167 NCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH 1226
C C K+F++ L H IHTGEKPY C++CGK+F S+L H H+ QKL+ C
Sbjct: 313 K-CKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCE 371
Query: 1227 VCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP 1278
C AF+ SL H R+HTG KP+ C C F S H + H P
Sbjct: 372 ECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKP 423
Score = 123 bits (309), Expect = 1e-27
Identities = 72/264 (27%), Positives = 111/264 (42%), Gaps = 36/264 (13%)
Query: 533 TGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHT 592
T K F+C C+K FS + H HTG +PF C C + F S H+ H
Sbjct: 140 TQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMS-----HLTQHTGIH 194
Query: 593 ELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNE 652
K K K T++ + ++
Sbjct: 195 AGEKPYKCEKCGKAFNRSTSLS-------------------------------KHKRIHT 223
Query: 653 ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKS 712
++PY C C +A+++S L +H + HTGEKP+KC +CG+ F + L H + HTG K
Sbjct: 224 GEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKP 283
Query: 713 FKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQ 772
+KC C AF SL H IH +PY C C K F+ S + +H H E +
Sbjct: 284 YKCKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCE 343
Query: 773 QHQQAASIDDSTVDQQSMQASTQM 796
+ +A + S + +S+ + ++
Sbjct: 344 KCGKAFNQSSSLIIHRSIHSEQKL 367
Score = 122 bits (305), Expect = 4e-27
Identities = 65/160 (40%), Positives = 91/160 (56%), Gaps = 16/160 (10%)
Query: 1643 NLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLK 1702
N+ G +P K C EC +AF+ ++ L+ H + +H ++++ C C KAF R+T L
Sbjct: 500 NIHTGEKPYK------CKECGKAFNQSSGLIIH-RSIHSEQKLYKCEECGKAFTRSTALN 552
Query: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
EH + H S +KP +KC C KA+ S L +H RIHTGE+PF C C KAFN
Sbjct: 553 EHKKIH------SGEKP--YKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWS 604
Query: 1763 SALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
S+L H HTGE+ YKC C F + S + +H KR H+
Sbjct: 605 SSLTKHKIIHTGEKSYKCEECGKAFNRPSTLTVH-KRIHT 643
Score = 117 bits (294), Expect = 8e-26
Identities = 56/156 (35%), Positives = 91/156 (58%), Gaps = 15/156 (9%)
Query: 1643 NLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLK 1702
N+ G +P + C +C +AF+ ++ L+ H + +H ++++ C C KAF ++ L
Sbjct: 332 NIHTGEKP------YTCEKCGKAFNQSSSLIIH-RSIHSEQKLYKCEECGKAFTWSSSLN 384
Query: 1703 EHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
+H + H + +KP + C+ C KAF + S L +H RIHTGE+P+ C C KAFNQ
Sbjct: 385 KHKRIH------TGEKP--YTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQS 436
Query: 1763 SALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
S L +H + H+G++PYKC C FT+ + + H K
Sbjct: 437 STLILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKK 472
Score = 117 bits (293), Expect = 1e-25
Identities = 58/142 (40%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC +AF + VL H K++H E+ + C C KAF R+T L EH + H
Sbjct: 226 KPYTCEECGKAFRRSTVLNEH-KKIHTGEKPYKCEECGKAFTRSTTLNEHKKIH------ 278
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF + L H IHTGE+P+ C C KAF Q +L H HTG
Sbjct: 279 TGEKP--YKCKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTG 336
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PY C C F Q S++ +H
Sbjct: 337 EKPYTCEKCGKAFNQSSSLIIH 358
Score = 117 bits (292), Expect = 1e-25
Identities = 57/148 (38%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AF+ + L H K +H E+ + C C KAF+R+T L EH + H
Sbjct: 198 KPYKCEKCGKAFNRSTSLSKH-KRIHTGEKPYTCEECGKAFRRSTVLNEHKKIH------ 250
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF + + L H +IHTGE+P+ C C KAF ++L H HTG
Sbjct: 251 TGEKP--YKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTG 308
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F Q ++ H K H+
Sbjct: 309 EKPYKCKECGKAFRQSRSLNEH-KNIHT 335
Score = 116 bits (291), Expect = 2e-25
Identities = 66/183 (36%), Positives = 97/183 (53%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ + L H K++H E+ + C C KAF+ +T L EH H
Sbjct: 254 KPYKCEECGKAFTRSTTLNEH-KKIHTGEKPYKCKECGKAFRWSTSLNEHKNIH------ 306
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF + L H IHTGE+P+ C C KAFNQ S+L +H H+
Sbjct: 307 TGEKP--YKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSE 364
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
++ YKC C FT S++ H KR H+ E E+ G+ R+ HL + +
Sbjct: 365 QKLYKCEECGKAFTWSSSLNKH-KRIHT-----GEKPYTCEECGKAFYRSSHLAKHKRIH 418
Query: 1835 AGE 1837
GE
Sbjct: 419 TGE 421
Score = 116 bits (291), Expect = 2e-25
Identities = 69/207 (33%), Positives = 106/207 (51%), Gaps = 31/207 (14%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH---- 1708
E + ++C EC +AF+ ++ L H K +H E+ + C C KAF R++HL +H + H
Sbjct: 364 EQKLYKCEECGKAFTWSSSLNKH-KRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEK 422
Query: 1709 -----QAGPSL-------------SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
+ G + S QKP +KC+ C KAF + + L H +IHTGE+P+
Sbjct: 423 PYTCEECGKAFNQSSTLILHKRIHSGQKP--YKCEECGKAFTRSTTLNEHKKIHTGEKPY 480
Query: 1751 HCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810
C C KAF ++L H HTGE+PYKC C F Q S + +H + HS ++
Sbjct: 481 KCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIH-RSIHS-----EQK 534
Query: 1811 AGHPEQDGEELSRTLHLEEVVQEAAGE 1837
E+ G+ +R+ L E + +GE
Sbjct: 535 LYKCEECGKAFTRSTALNEHKKIHSGE 561
Score = 115 bits (289), Expect = 3e-25
Identities = 60/162 (37%), Positives = 90/162 (55%), Gaps = 10/162 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S +LA + + + C EC +AF+ ++ L+ H K +H ++ + C C KAF R+T
Sbjct: 408 SSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILH-KRIHSGQKPYKCEECGKAFTRSTT 466
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L EH + H + +KP +KC+ C KAF + L H IHTGE+P+ C C KAFN
Sbjct: 467 LNEHKKIH------TGEKP--YKCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFN 518
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
Q S L +H H+ ++ YKC C FT+ + + H K+ HS
Sbjct: 519 QSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEH-KKIHS 559
Score = 103 bits (256), Expect = 2e-21
Identities = 54/146 (36%), Positives = 78/146 (53%), Gaps = 10/146 (6%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
+ + QC C + FS + H K H E+ C C ++F + HL +H H
Sbjct: 141 QSKIFQCNTCVKVFSKFSNSNKH-KIRHTGEKPFKCTECGRSFYMS-HLTQHTGIH---- 194
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
+ +KP +KC+ C KAF + + L +H RIHTGE+P+ C C KAF + + L H K H
Sbjct: 195 --AGEKP--YKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIH 250
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMK 1798
TGE+PYKC C FT+ + + H K
Sbjct: 251 TGEKPYKCEECGKAFTRSTTLNEHKK 276
Score = 92.8 bits (229), Expect = 3e-18
Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 9/123 (7%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
E + ++C EC +AF+ + L H K++H E+ + C C KA+ ++ L +H + H
Sbjct: 532 EQKLYKCEECGKAFTRSTALNEH-KKIHSGEKPYKCKECGKAYNLSSTLTKHKRIH---- 586
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
+ +KP F C+ C KAF S L +H IHTGE+ + C C KAFN+ S L VH + H
Sbjct: 587 --TGEKP--FTCEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGKAFNRPSTLTVHKRIH 642
Query: 1773 TGE 1775
TG+
Sbjct: 643 TGK 645
Score = 88.2 bits (217), Expect = 7e-17
Identities = 39/115 (33%), Positives = 57/115 (49%)
Query: 959 NEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHT 1018
N + Y+C C K F +SS L H H+ +K YKC+ CG+ F S L H+K H+
Sbjct: 500 NIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHS 559
Query: 1019 GVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
G K + C C ++ + +LT+H H KP+ C C + F + KH H
Sbjct: 560 GEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIH 614
Score = 78.6 bits (192), Expect = 5e-14
Identities = 42/112 (37%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Query: 1692 RKAFKRATHLKEHMQTHQAG-PSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
RK KR K + LS+ + ++F+C+TC K F+K S +H HTGE+PF
Sbjct: 114 RKGCKRVNECKVQKGVNNGVYQCLSTTQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPF 173
Query: 1751 HCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
CT C ++F S L H H GE+PYKC C F + +++ H KR H+
Sbjct: 174 KCTECGRSF-YMSHLTQHTGIHAGEKPYKCEKCGKAFNRSTSLSKH-KRIHT 223
Score = 60.5 bits (145), Expect = 2e-08
Identities = 33/89 (37%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 678 SHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHND 737
S T K F+C+ C + F H HTG K FKC C +F L +H GIH
Sbjct: 138 STTQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYM-SHLTQHTGIHAG 196
Query: 738 LRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+PY C C K F S + KH + H E
Sbjct: 197 EKPYKCEKCGKAFNRSTSLSKHKRIHTGE 225
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C ++ S +H R H +KP C++C + FN +LT HK H+GE C
Sbjct: 564 YKCKECGKAYNLSSTLTKHKRIHT-GEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSYKC 622
Query: 96 PVCNKKFSRVASLKAHIMLHEKEEN 120
C K F+R ++L H +H +E+
Sbjct: 623 EECGKAFNRPSTLTVHKRIHTGKEH 647
Score = 44.7 bits (104), Expect = 9e-04
Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 1218 TGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPD 1277
T K+F C+ C FS + H HTG KPFKC C F S H H
Sbjct: 140 TQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMS-HLTQHTGIHAGEK 198
Query: 1278 PKKARK 1283
P K K
Sbjct: 199 PYKCEK 204
>gi|57165428 zinc finger protein 28 [Homo sapiens]
Length = 665
Score = 236 bits (601), Expect = 2e-61
Identities = 168/628 (26%), Positives = 254/628 (40%), Gaps = 118/628 (18%)
Query: 114 LHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMK 173
+H +E++ C E G F S L H H +E +Q C K F L H +
Sbjct: 155 VHMREKSFQCIESGKSFNCSSLLKKHQITHLEE----KQCKCDVYGKVFNQKRYLACHRR 210
Query: 174 THYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKA 233
+H ID Y C CGK F + L H +HT ++P++C EC K
Sbjct: 211 SH--------------IDEK--PYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKV 254
Query: 234 FNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCV 293
F++K L+TH I +TG KP+ C C AF+ L H +H+ K Y C EC V
Sbjct: 255 FSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTI-IHTGEK---PYKCNECGKV 310
Query: 294 FKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQA 353
F L +L H ++H G E
Sbjct: 311 FNRLSTLARH-RRLHTGEKPYECEECEK-------------------------------- 337
Query: 354 VSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPND 413
V + L + +G+ P + N + + ++ ++G
Sbjct: 338 ---VFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTG------------ 382
Query: 414 SCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSI 473
P+ N + V N+Q+ + E P K ++ +K + + L
Sbjct: 383 ------EKPYKCN-ECGKVFNQQSTLARHHRLHTAEKPYKCEECDK--VFRCKSHLERHR 433
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K FR S L H R+HT EKP+ C +C + F+ K+ L H K HT
Sbjct: 434 RIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHT 493
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTE 593
K +KC+ C K FS ++ H R+HTG +P+ C CDK FR R +H+A H
Sbjct: 494 AEKPYKCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDKAFR----RDSHLAQH----- 544
Query: 594 LRKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNE 652
+++ KP K GKT + + + +
Sbjct: 545 -QRVHTGEKPYKCNECGKTFRQTSSLIIHRRL--------------------------HT 577
Query: 653 ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKS 712
++PYKC C + + + L H R H+GEKP+KC++CG+ F L H R HTG K
Sbjct: 578 GEKPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKP 637
Query: 713 FKCLICNGAFTTGGSLRRHMGIHNDLRP 740
+KC C F+ +L H +H+ +P
Sbjct: 638 YKCNECGKTFSQMSNLVYHHRLHSGEKP 665
Score = 232 bits (592), Expect = 2e-60
Identities = 167/629 (26%), Positives = 249/629 (39%), Gaps = 120/629 (19%)
Query: 138 VHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTY 197
VHM E + C K F SS LK+H TH + +
Sbjct: 155 VHMRE--------KSFQCIESGKSFNCSSLLKKHQITHLEEKQCK--------------- 191
Query: 198 SCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAF 257
C GK F + L H R H E+P+KC+ECGK F +L H HT +KP+ C
Sbjct: 192 -CDVYGKVFNQKRYLACHRRSHIDEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEE 250
Query: 258 CPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTS 317
C FS+K +L++H + +++ G Y C C F L H + +H G +
Sbjct: 251 CDKVFSRKSHLETH-KIIYT---GGKPYKCKVCDKAFTCNSYLAKH-TIIHTG--EKPYK 303
Query: 318 STETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQ 377
E V F L + + + V + L + +G+ P
Sbjct: 304 CNECGKV-----FNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERHKRIHTGEKPY 358
Query: 378 PGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQT 437
+ N + + ++ ++G P+ N + V N+Q+
Sbjct: 359 KCKVCDKAFAYNSYLAKHSIIHTG------------------EKPYKCN-ECGKVFNQQS 399
Query: 438 DPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDL 497
+ E P K ++ +K + + L R G + + C C K FR S L
Sbjct: 400 TLARHHRLHTAEKPYKCEECDK--VFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCL 457
Query: 498 VRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHI 557
H R+HT EKP+ C +C + F+ K+ L H K HT K +KC+ C K FS ++ H
Sbjct: 458 TEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERHR 517
Query: 558 RLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPD 617
R+HTG +P+ C CDK FR R +H+A +HQR
Sbjct: 518 RIHTGEKPYKCKVCDKAFR----RDSHLA-----------QHQR---------------- 546
Query: 618 IPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIR 677
V+ ++PYKC C + ++++ L H R
Sbjct: 547 --------------------------------VHTGEKPYKCNECGKTFRQTSSLIIHRR 574
Query: 678 SHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHND 737
HTGEKP+KC++CG+ F L H R H+G K +KC C F L +H +H
Sbjct: 575 LHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTG 634
Query: 738 LRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+PY C C KTF N H + H E
Sbjct: 635 EKPYKCNECGKTFSQMSNLVYHHRLHSGE 663
Score = 212 bits (540), Expect = 2e-54
Identities = 152/533 (28%), Positives = 225/533 (42%), Gaps = 54/533 (10%)
Query: 57 RDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPT-CPVCNKKFSRVASLKAHIMLH 115
R+ +K +C + ++FN L H+ TH E C V K F++ L H H
Sbjct: 153 RNVHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSH 212
Query: 116 EKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH 175
E+ C+ECG F + L +H H + + + C+ C K F K H++TH
Sbjct: 213 IDEKPYKCNECGKIFGHNTSLFLHKALHTAD----KPYECEECDKVFSR----KSHLETH 264
Query: 176 YKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFN 235
+ I G Y C C K F S L +H IHTGE+P+KC+ECGK FN
Sbjct: 265 ------------KIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFN 312
Query: 236 QKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFK 295
+ L H HTGEKP+ C C FS+K +L+ H +R+H+ K Y C C F
Sbjct: 313 RLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERH-KRIHTGEK---PYKCKVCDKAFA 368
Query: 296 SLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVS 355
L H S +H G + +TL + L +A +
Sbjct: 369 YNSYLAKH-SIIHTGEKPYKCNECGKVFNQQSTLARHHRLH-------TAEKPYKCEECD 420
Query: 356 DVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSC 415
V + L + +G+ P + + +A + + H +
Sbjct: 421 KVFRCKSHLERHRRIHTGEKPYKCK-----------VCDKAFRSDSCLTEHQRVHTGEK- 468
Query: 416 HAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIRE 475
P+ N + V + + + + E P K ++ EK +K + R
Sbjct: 469 ------PYMCN-ECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKS--HMERHRRI 519
Query: 476 ENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGI 535
G + + C C K FR+ S L +H R+HT EKP+KC +C + F S+L H + HTG
Sbjct: 520 HTGEKPYKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGE 579
Query: 536 KAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
K +KC C K+FS SL H RLH+G +P+ C C K F H H H
Sbjct: 580 KPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVH 632
Score = 211 bits (538), Expect = 4e-54
Identities = 112/327 (34%), Positives = 160/327 (48%), Gaps = 20/327 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C+ C K F + SHL++H R HTGEKPYKCK+C + F + L H HTG K +
Sbjct: 328 KPYECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYK 387
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTV-----PSA 1079
C+ C F +L RH H + KPYKC C++ FR CK H++RH+ + P
Sbjct: 388 CNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKVFR----CKSHLERHRRIHTGEKPYK 443
Query: 1080 VSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
+ D C+ E + +P + + + A + +EK
Sbjct: 444 CKVCDKAFRSDSCLTEHQR-----VHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPY 498
Query: 1140 VQSAAEK--DRISEL-RDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYK 1196
EK R S + R ++ ++P C C K+F++ S L +H R+HTGEKPYK
Sbjct: 499 KCEECEKVFSRKSHMERHRRIHTGEKPYK---CKVCDKAFRRDSHLAQHQRVHTGEKPYK 555
Query: 1197 CDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHC 1256
C+ECGK+F S+L H + HTG+K + C+ C FS SL H RLH+G KP+KC C
Sbjct: 556 CNECGKTFRQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNEC 615
Query: 1257 ELRFRTSGRRKTHMQFHYKPDPKKARK 1283
F H + H P K +
Sbjct: 616 GKVFNQQAHLAQHQRVHTGEKPYKCNE 642
Score = 194 bits (494), Expect = 5e-49
Identities = 112/342 (32%), Positives = 159/342 (46%), Gaps = 26/342 (7%)
Query: 953 SQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS 1012
S FL + + Y C+ C+K F + SHL+ H +TG KPYKCK+C + F + L
Sbjct: 232 SLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAK 291
Query: 1013 HEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKR 1072
H HTG K + C+ C F +L RH H KPY+C CE+ F H ++H +
Sbjct: 292 HTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERHKRI 351
Query: 1073 HQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEE--ETAQLAKIRPQE 1130
H TGE ++ ++ S ++ +I E+ + + K+ Q+
Sbjct: 352 H---------TGEKPYKCKVCDKAFAYN----SYLAKHSIIHTGEKPYKCNECGKVFNQQ 398
Query: 1131 SATVSEKVLVQSAAEKDRISELRDKQAELQDE-PKHANC--------CTYCPKSFKKPSD 1181
S L AEK E DK + +H C C K+F+ S
Sbjct: 399 STLARHHRL--HTAEKPYKCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSC 456
Query: 1182 LVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVH 1241
L H R+HTGEKPY C+ECGK F+ K+ L CH K HT +K + C C FS K ++ H
Sbjct: 457 LTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERH 516
Query: 1242 MRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
R+HTG KP+KC C+ FR H + H P K +
Sbjct: 517 RRIHTGEKPYKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNE 558
Score = 187 bits (475), Expect = 8e-47
Identities = 104/275 (37%), Positives = 142/275 (51%), Gaps = 27/275 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C F +S +RH R H +KP++C C + F + LT H+ H+GE P C
Sbjct: 414 YKCEECDKVFRCKSHLERHRRIHT-GEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMC 472
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS A+L H LH E+ C EC F+ +S HME HR+ G + + C
Sbjct: 473 NECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKS----HMERHRRIHTGEKPYKC 528
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
K C K F S L +H + H + Y C CGKTF++ S L H
Sbjct: 529 KVCDKAFRRDSHLAQHQRVHTGEK----------------PYKCNECGKTFRQTSSLIIH 572
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
R+HTGE+P+KC+ECGK F+Q +L H H+GEKP+ C C F+Q+ +L H QRV
Sbjct: 573 RRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQH-QRV 631
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C EC F + +L H ++H G
Sbjct: 632 HTGEK---PYKCNECGKTFSQMSNLVYH-HRLHSG 662
Score = 179 bits (454), Expect = 2e-44
Identities = 98/288 (34%), Positives = 145/288 (50%), Gaps = 32/288 (11%)
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ + Y+C+ C+K F+ SHL++H R HTGEKPYKCK+C + F S L H++ HTG K
Sbjct: 410 AEKPYKCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKP 469
Query: 1023 FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSA 1082
+ C+ C F+T +L H H + KPYKC CE+ F K HM+RH+ +
Sbjct: 470 YMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSR----KSHMERHRRI-----H 520
Query: 1083 TGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQS 1142
TGE + + +V + LA+ + + K
Sbjct: 521 TGE--------------------KPYKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECG 560
Query: 1143 AAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
+ S + ++ ++P C C K+F + S LV H R+H+GEKPYKC+ECGK
Sbjct: 561 KTFRQTSSLIIHRRLHTGEKPYK---CNECGKTFSQMSSLVYHHRLHSGEKPYKCNECGK 617
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKP 1250
F ++ L H + HTG+K + C+ C FS +L H RLH+G KP
Sbjct: 618 VFNQQAHLAQHQRVHTGEKPYKCNECGKTFSQMSNLVYHHRLHSGEKP 665
Score = 176 bits (446), Expect = 2e-43
Identities = 104/319 (32%), Positives = 144/319 (45%), Gaps = 32/319 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F ++ L H HT +KPY+C+ C + F L++H+ +TG K +
Sbjct: 216 KPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYK 275
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C VC+ +FT N L +H H KPYKC C + F +H + H TG
Sbjct: 276 CKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLH---------TG 326
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E E E ++ SRKS E T + +P + + S
Sbjct: 327 E-------KPYECEECEKVFSRKSHLE--RHKRIHTGE----KPYKCKVCDKAFAYNSYL 373
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
K I +K + C C K F + S L RH R+HT EKPYKC+EC K F
Sbjct: 374 AKHSIIHTGEKPYK----------CNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKVF 423
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
KS L+ H + HTG+K + C VC AF + L H R+HTG KP+ C C F T
Sbjct: 424 RCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTKA 483
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H + H P K +
Sbjct: 484 NLACHHKLHTAEKPYKCEE 502
Score = 175 bits (444), Expect = 3e-43
Identities = 104/332 (31%), Positives = 153/332 (46%), Gaps = 39/332 (11%)
Query: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
E P K ++ K S FL ++ + + + C C K F + S L H I+T K
Sbjct: 215 EKPYKCNECGKIFGHNTSLFLHKALHTAD--KPYECEECDKVFSRKSHLETHKIIYTGGK 272
Query: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFAC 568
P+KC C +AF S L H HTG K +KC C K F+ +L H RLHTG +P+ C
Sbjct: 273 PYKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYEC 332
Query: 569 PHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITD 628
C+K F RK+H+ H +++ KP K +V
Sbjct: 333 EECEKVFS----RKSHLERH------KRIHTGEKPYKCKV-------------------- 362
Query: 629 LGLIQPIPKNQFFQSYF-NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKC 687
K + SY ++ ++ ++PYKC C + + + L +H R HT EKP+KC
Sbjct: 363 ------CDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKC 416
Query: 688 SQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQ 747
+C + F L+ H R HTG K +KC +C+ AF + L H +H +PYMC C
Sbjct: 417 EECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECG 476
Query: 748 KTFKTSLNCKKHMKTHRYELAQQLQQHQQAAS 779
K F T N H K H E + ++ ++ S
Sbjct: 477 KVFSTKANLACHHKLHTAEKPYKCEECEKVFS 508
Score = 166 bits (421), Expect = 1e-40
Identities = 98/287 (34%), Positives = 136/287 (47%), Gaps = 23/287 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
++CE C F ++S + H + KP++C C + F L H H+GE P C
Sbjct: 246 YECEECDKVFSRKSHLETHKIIYT-GGKPYKCKVCDKAFTCNSYLAKHTIIHTGEKPYKC 304
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+R+++L H LH E+ C EC F+ +S H+E H++ G + + C
Sbjct: 305 NECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKS----HLERHKRIHTGEKPYKC 360
Query: 156 KACKKEFETSSELKEHMKTH-----YK-------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
K C K F +S L +H H YK ST + + + + Y C C
Sbjct: 361 KVCDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKCEECD 420
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S L RH RIHTGE+P+KC C KAF L H HTGEKP+ C C FS
Sbjct: 421 KVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFS 480
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
K NL H ++H+ K Y C EC VF + H ++H G
Sbjct: 481 TKANLACH-HKLHTAEK---PYKCEECEKVFSRKSHMERH-RRIHTG 522
Score = 158 bits (400), Expect = 4e-38
Identities = 93/274 (33%), Positives = 129/274 (47%), Gaps = 27/274 (9%)
Query: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCP 96
KC++ F ++ H R H ++KP++C++C + F +L LHK H+ + P C
Sbjct: 191 KCDVYGKVFNQKRYLACHRRSHI-DEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECE 249
Query: 97 VCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK 156
C+K FSR + L+ H +++ + C C FT S LA H H G + + C
Sbjct: 250 ECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIH----TGEKPYKCN 305
Query: 157 ACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHI 216
C K F S L H + H + Y C C K F + S L RH
Sbjct: 306 ECGKVFNRLSTLARHRRLHTGEK----------------PYECEECEKVFSRKSHLERHK 349
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
RIHTGE+P+KC C KAF L H I HTGEKP+ C C F+Q+ L H R+H
Sbjct: 350 RIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARH-HRLH 408
Query: 277 SEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
+ K Y C EC VF+ L H ++H G
Sbjct: 409 TAEK---PYKCEECDKVFRCKSHLERH-RRIHTG 438
Score = 145 bits (365), Expect = 5e-34
Identities = 97/327 (29%), Positives = 131/327 (40%), Gaps = 64/327 (19%)
Query: 959 NEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHT 1018
N +S++C K F SS LK+H +H EK KC + G+ F L H ++H
Sbjct: 154 NVHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHI 213
Query: 1019 GVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPS 1078
K + C+ C F N SL H A H + KPY+C
Sbjct: 214 DEKPYKCNECGKIFGHNTSLFLHKALHTADKPYEC------------------------- 248
Query: 1079 AVSATGETEGGDICMEEEEEHSDRNASRKSRPEV--ITFTEEETAQLAKIRPQESATVSE 1136
E D+ SRKS E I +T +P + +
Sbjct: 249 -------------------EECDKVFSRKSHLETHKIIYTGG--------KPYKCKVCDK 281
Query: 1137 KVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYK 1196
S K I +K + C C K F + S L RH R+HTGEKPY+
Sbjct: 282 AFTCNSYLAKHTIIHTGEKPYK----------CNECGKVFNRLSTLARHRRLHTGEKPYE 331
Query: 1197 CDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHC 1256
C+EC K F+ KS L+ H + HTG+K + C VC AF+ L H +HTG KP+KC C
Sbjct: 332 CEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNEC 391
Query: 1257 ELRFRTSGRRKTHMQFHYKPDPKKARK 1283
F H + H P K +
Sbjct: 392 GKVFNQQSTLARHHRLHTAEKPYKCEE 418
Score = 124 bits (311), Expect = 8e-28
Identities = 60/148 (40%), Positives = 87/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC + FS+ A L H K +H E+ + C C K F R +H++ H + H
Sbjct: 468 KPYMCNECGKVFSTKANLACHHK-LHTAEKPYKCEECEKVFSRKSHMERHRRIH------ 520
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C+KAF + S L +H R+HTGE+P+ C C K F Q S+L +H + HTG
Sbjct: 521 TGEKP--YKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTG 578
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F+Q S++ H R HS
Sbjct: 579 EKPYKCNECGKTFSQMSSLVYH-HRLHS 605
Score = 123 bits (308), Expect = 2e-27
Identities = 61/148 (41%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C CD+AF S + L H + VH E+ + C C K F +L H + H A
Sbjct: 440 KPYKCKVCDKAFRSDSCLTEHQR-VHTGEKPYMCNECGKVFSTKANLACHHKLHTA---- 494
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP +KC+ CEK F++ S +ERH RIHTGE+P+ C +C+KAF + S L H + HTG
Sbjct: 495 --EKP--YKCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHQRVHTG 550
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F Q S++ +H +R H+
Sbjct: 551 EKPYKCNECGKTFRQTSSLIIH-RRLHT 577
Score = 119 bits (299), Expect = 2e-26
Identities = 66/195 (33%), Positives = 102/195 (52%), Gaps = 27/195 (13%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
C E +V NLA ++ + ++C EC++ FS + + H + +H E+ + C
Sbjct: 472 CNECG-KVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERH-RRIHTGEKPYKCK 529
Query: 1690 VCRKAFKRATHLKEHMQTH---------QAGPSL-------------SSQKPRVFKCDTC 1727
VC KAF+R +HL +H + H + G + + +KP +KC+ C
Sbjct: 530 VCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKP--YKCNEC 587
Query: 1728 EKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGF 1787
K F++ S L H R+H+GE+P+ C C K FNQ++ L H + HTGE+PYKC C F
Sbjct: 588 GKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNECGKTF 647
Query: 1788 TQKSNMKLHMKRAHS 1802
+Q SN+ H R HS
Sbjct: 648 SQMSNLVYH-HRLHS 661
Score = 119 bits (298), Expect = 3e-26
Identities = 58/143 (40%), Positives = 84/143 (58%), Gaps = 9/143 (6%)
Query: 1654 GRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPS 1713
G+ ++C CD+AF+ + L H+ +H E+ + C C K F R + L H + H
Sbjct: 271 GKPYKCKVCDKAFTCNSYLAKHTI-IHTGEKPYKCNECGKVFNRLSTLARHRRLH----- 324
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
+ +KP ++C+ CEK F++ S LERH RIHTGE+P+ C +C+KAF S L H HT
Sbjct: 325 -TGEKP--YECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHT 381
Query: 1774 GERPYKCAYCVMGFTQKSNMKLH 1796
GE+PYKC C F Q+S + H
Sbjct: 382 GEKPYKCNECGKVFNQQSTLARH 404
Score = 118 bits (295), Expect = 6e-26
Identities = 58/144 (40%), Positives = 83/144 (57%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C CD+AF+ + L HS +H E+ + C C K F + + L H + H A
Sbjct: 356 KPYKCKVCDKAFAYNSYLAKHSI-IHTGEKPYKCNECGKVFNQQSTLARHHRLHTA---- 410
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP +KC+ C+K F S LERH RIHTGE+P+ C +C+KAF S L H + HTG
Sbjct: 411 --EKP--YKCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTG 466
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY C C F+ K+N+ H K
Sbjct: 467 EKPYMCNECGKVFSTKANLACHHK 490
Score = 112 bits (279), Expect = 4e-24
Identities = 57/148 (38%), Positives = 84/148 (56%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F L H K +H ++ + C C K F R +HL+ H + G
Sbjct: 216 KPYKCNECGKIFGHNTSLFLH-KALHTADKPYECEECDKVFSRKSHLETHKIIYTGG--- 271
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
KP +KC C+KAF S L +H+ IHTGE+P+ C C K FN+ S L H + HTG
Sbjct: 272 ---KP--YKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTG 326
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C C F++KS+++ H KR H+
Sbjct: 327 EKPYECEECEKVFSRKSHLERH-KRIHT 353
Score = 77.8 bits (190), Expect = 9e-14
Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 8/125 (6%)
Query: 1672 LMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAF 1731
L+ + VH RE+ C K+F ++ LK+H TH + + KCD K F
Sbjct: 148 LLTQKRNVHMREKSFQCIESGKSFNCSSLLKKHQITHL--------EEKQCKCDVYGKVF 199
Query: 1732 AKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKS 1791
+ L H R H E+P+ C C K F ++L +H HT ++PY+C C F++KS
Sbjct: 200 NQKRYLACHRRSHIDEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKS 259
Query: 1792 NMKLH 1796
+++ H
Sbjct: 260 HLETH 264
Score = 69.3 bits (168), Expect = 3e-11
Identities = 41/139 (29%), Positives = 60/139 (43%), Gaps = 14/139 (10%)
Query: 636 PKNQFFQSYFNNNF----------VNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPF 685
PK Y NN+ V+ ++ ++C +++ S LK+H +H EK
Sbjct: 131 PKTHISNKYGNNSLHSSLLTQKRNVHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQC 190
Query: 686 KCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPY 745
KC G+ F L H R+H K +KC C F SL H +H +PY C
Sbjct: 191 KCDVYGKVFNQKRYLACHRRSHIDEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEE 250
Query: 746 CQKTFKTSLNCKKHMKTHR 764
C K F K H++TH+
Sbjct: 251 CDKVFSR----KSHLETHK 265
Score = 38.1 bits (87), Expect = 0.080
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 1735 SQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMK 1794
S L + +H E+ F C K+FN S L+ H H E+ KC F QK +
Sbjct: 147 SLLTQKRNVHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLA 206
Query: 1795 LHMKRAH 1801
H +R+H
Sbjct: 207 CH-RRSH 212
Score = 32.0 bits (71), Expect = 5.7
Identities = 26/110 (23%), Positives = 36/110 (32%)
Query: 1174 KSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFS 1233
KS S + RI K + ++ G + S L H +K F C +F+
Sbjct: 113 KSINNASSVSTSQRICCRPKTHISNKYGNNSLHSSLLTQKRNVHMREKSFQCIESGKSFN 172
Query: 1234 TKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
LK H H K KC F H + H P K +
Sbjct: 173 CSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHIDEKPYKCNE 222
>gi|122937229 zinc finger protein 629 [Homo sapiens]
Length = 869
Score = 229 bits (584), Expect = 2e-59
Identities = 185/716 (25%), Positives = 285/716 (39%), Gaps = 124/716 (17%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F + + +H R H +KP++C +C + F +L H+ TH+GE P C
Sbjct: 234 YKCTECEKAFTQSTNLIKHQRSHT-GEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKC 292
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
P C K+F + +L H +H E+ C+ECG F S+L H H G + + C
Sbjct: 293 PECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTH----TGEKPYEC 348
Query: 156 KACKKEFETSSELKEHMKTHYK------------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
C K F SS L +H +TH + +S+T ++ Y CP CG
Sbjct: 349 LECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECG 408
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K+F S L H RIH GERP+ C++CGK+F L H HTGEKP+ C+ C +F
Sbjct: 409 KSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFI 468
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAH 323
+ +L H +R H+ K Y C EC F +L TH+ + HM S A
Sbjct: 469 RSSHLIQH-RRTHTGEK---PYKCPECGKSFSQSSNLITHV-RTHMDENLFVCSDCGKAF 523
Query: 324 VLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLS 383
+ L Q + + P+ +A D LL L +P+ + +P + L
Sbjct: 524 LEAHELEQHRVIHER-------GKTPARRAQGD---SLLGLGDPSLLTPPPGAKPHKCLV 573
Query: 384 ITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAE 443
G N + + + + P HA P ++P + N P AE
Sbjct: 574 CGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSY--PGAAE 631
Query: 444 QEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRI 503
E + ++ ++ L + ++C +C + F S L++H
Sbjct: 632 GRAEAPGQPLKPPEGQEGFSQRRGLLSS--------KTYICSHCGESFLDRSVLLQHQLT 683
Query: 504 HTHEKPF------------------------KCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
H +EKPF KCP+C ++F + S L H K H G K+
Sbjct: 684 HGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKS-- 741
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF----RTSGHRKTHIASHFKHTELR 595
Q + +S L H+R G RP+ C C F + H++TH
Sbjct: 742 SQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHT---------- 791
Query: 596 KMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADR 655
Q KP P P+ P E + + + + E +
Sbjct: 792 ----QEKP----------PNPEDPPPEAVTL-------------------STDQEGEGET 818
Query: 656 PYKCFYCHRAYKKSCHLK-QHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGL 710
P + S H + Q+ ++ EKP+ C +CG GF L H H G+
Sbjct: 819 P-------TPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCHPGV 867
Score = 208 bits (530), Expect = 3e-53
Identities = 186/691 (26%), Positives = 276/691 (39%), Gaps = 80/691 (11%)
Query: 427 PDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPY 486
PD + ++ ++ E P K + EK + + L R G + + C
Sbjct: 209 PDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTN--LIKHQRSHTGEKPYKCGE 266
Query: 487 CAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKS 546
C + F + SDL++H HT EKP+KCP+C + F L H K H G K ++C C KS
Sbjct: 267 CRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKS 326
Query: 547 FSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH-FKHTELRK----- 596
F S L H R HTG +P+ C C K F S H++TH+ FK K
Sbjct: 327 FIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLS 386
Query: 597 ---MRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEA 653
+RHQR R P + G + N N+ ++
Sbjct: 387 ATLLRHQRTHTGER---------------PYKCPECGKSFSVSSN-----LINHQRIHRG 426
Query: 654 DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSF 713
+RPY C C +++ S L +H R HTGEKP+KCS CG+ F+ + L H RTHTG K +
Sbjct: 427 ERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPY 486
Query: 714 KCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTH-RYELAQQLQ 772
KC C +F+ +L H+ H D ++C C K F + ++H H R + +
Sbjct: 487 KCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRA 546
Query: 773 QHQQAASIDDSTVDQQSMQASTQMQV------EIESDELPQTAEVVAANPEAMLDLEPQH 826
Q + D ++ A + E + + NP D
Sbjct: 547 QGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNAD----- 601
Query: 827 VVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTV 886
GL A +P + +P+ P RG+ + A+ +P P+G
Sbjct: 602 -------GLIAHAAPKPPQ-----LRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEG--- 646
Query: 887 TDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEEL 946
Q F + L S T SF +S+L N L + + L
Sbjct: 647 ------QEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPD-YRIGL 699
Query: 947 DLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEK-PYKCKLCGRGFV 1005
A S FL S + ++C C + F SS L H + H G K K G+
Sbjct: 700 GEGAGPSPFL------SGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGK--- 750
Query: 1006 SSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVH 1065
SS VL H ++ G + + CS C ASF +LTRH TH KP P T+
Sbjct: 751 SSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPN-PEDPPPEAVTLS 809
Query: 1066 CKKHMKRHQTVPSAVSATGETEGGDICMEEE 1096
+ + P+ S+ GE + +EE+
Sbjct: 810 TDQEGEGETPTPTESSSHGEGQNPKTLVEEK 840
Score = 196 bits (498), Expect = 2e-49
Identities = 112/317 (35%), Positives = 152/317 (47%), Gaps = 20/317 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F SS+L QH R+HTGEKPYKC C + F S L H+++HTG K +
Sbjct: 204 KPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYK 263
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + L +H ATH KPYKCP C + F + KH K H G
Sbjct: 264 CGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIH---------AG 314
Query: 1085 E-----TEGGDICMEEEEEHSDRNASRKSRP-EVITFTEEETAQLAKIRPQESATVSEKV 1138
E TE G ++ E + +P E + + I+ Q + +
Sbjct: 315 EKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPF 374
Query: 1139 LVQSAAEKDRISE--LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYK 1196
+ +S LR ++ + P C C KSF S+L+ H RIH GE+PY
Sbjct: 375 KCPVCGKTFTLSATLLRHQRTHTGERPYK---CPECGKSFSVSSNLINHQRIHRGERPYI 431
Query: 1197 CDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHC 1256
C +CGKSF + STL H + HTG+K + C C +F L H R HTG KP+KCP C
Sbjct: 432 CADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPEC 491
Query: 1257 ELRFRTSGRRKTHMQFH 1273
F S TH++ H
Sbjct: 492 GKSFSQSSNLITHVRTH 508
Score = 196 bits (497), Expect = 2e-49
Identities = 127/398 (31%), Positives = 183/398 (45%), Gaps = 18/398 (4%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
R C C K F +SSHL QH R+HTGEKPYKC CG+ F S L H++THTG K +
Sbjct: 176 RPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYK 235
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSAT 1083
C+ C +FT + +L +H +H KPYKC C F + +H H P
Sbjct: 236 CTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPEC 295
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEK---VLV 1140
G+ G + +H +A K P T + Q +++ + EK L
Sbjct: 296 GKRFGQN---HNLLKHQKIHAGEK--PYRCTECGKSFIQSSELTQHQRTHTGEKPYECLE 350
Query: 1141 QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
+ + ++ ++ L+++P C C K+F + L+RH R HTGE+PYKC EC
Sbjct: 351 CGKSFGHSSTLIKHQRTHLREDPFK---CPVCGKTFTLSATLLRHQRTHTGERPYKCPEC 407
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF 1260
GKSF+V S L H + H G++ + C C +F +L H R+HTG KP+KC C F
Sbjct: 408 GKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSF 467
Query: 1261 RTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSST--DPNVFIMNNSVLTG 1318
S H + H P K Q NL+ T D N+F+ ++
Sbjct: 468 IRSSHLIQHRRTHTGEKPYKC----PECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAF 523
Query: 1319 QFDQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLAT 1356
L Q ++ + + A GD + L D SL T
Sbjct: 524 LEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLT 561
Score = 191 bits (486), Expect = 4e-48
Identities = 104/295 (35%), Positives = 142/295 (48%), Gaps = 39/295 (13%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G R + C C K F + S LV+H R HT EKP+KCP C + F+ S L H +THT
Sbjct: 170 RIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHT 229
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTE 593
G K +KC C K+F+ S +L H R HTG +P+ C C + F S H A+H
Sbjct: 230 GEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATH----- 284
Query: 594 LRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSY--FNNNFVN 651
KP K P +F Q++ + ++
Sbjct: 285 -----TGEKPYKC---------------------------PECGKRFGQNHNLLKHQKIH 312
Query: 652 EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLK 711
++PY+C C +++ +S L QH R+HTGEKP++C +CG+ F + L H RTH
Sbjct: 313 AGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLRED 372
Query: 712 SFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
FKC +C FT +L RH H RPY CP C K+F S N H + HR E
Sbjct: 373 PFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGE 427
Score = 173 bits (438), Expect = 2e-42
Identities = 109/347 (31%), Positives = 151/347 (43%), Gaps = 67/347 (19%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F ++ +L +H + H GEKPY+C CG+ F+ S L H++THTG K +
Sbjct: 288 KPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYE 347
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C SF + +L +H TH+ P+KCP C + F + +H + H TG
Sbjct: 348 CLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTH---------TG 398
Query: 1085 ETEGGDICMEEEEEHSDR----NASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
E C E + S N R R E RP A + ++
Sbjct: 399 ERPYK--CPECGKSFSVSSNLINHQRIHRGE---------------RPYICADCGKSFIM 441
Query: 1141 QSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDEC 1200
S +R ++ ++P C+ C KSF + S L++H R HTGEKPYKC EC
Sbjct: 442 SSTL-------IRHQRIHTGEKPYK---CSDCGKSFIRSSHLIQHRRTHTGEKPYKCPEC 491
Query: 1201 GKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHT-------------- 1246
GKSF+ S L HV+TH + LF C C AF L+ H +H
Sbjct: 492 GKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSL 551
Query: 1247 -------------GAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK 1280
GAKP KC C F G H + H +P K
Sbjct: 552 LGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYK 598
Score = 172 bits (437), Expect = 2e-42
Identities = 164/707 (23%), Positives = 270/707 (38%), Gaps = 87/707 (12%)
Query: 63 DKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENL 121
+KP+ C++C ++F+ L H+ H+GE P TC C K F++ + L H H E+
Sbjct: 147 EKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPY 206
Query: 122 ICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----Y 176
C +CG F+ S L H H G + + C C+K F S+ L +H ++H Y
Sbjct: 207 KCPDCGKCFSWSSNLVQHQRTH----TGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPY 262
Query: 177 KIRVSSTRSYNRNID--------RSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCS 228
K R++ R+ D Y CP CGK F + L +H +IH GE+P++C+
Sbjct: 263 KCG-ECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCT 321
Query: 229 ECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCT 288
ECGK+F Q L H HTGEKP+ C C +F L H QR H ++ P + C
Sbjct: 322 ECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKH-QRTH--LREDP-FKCP 377
Query: 289 ECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQ 348
C F +L H + H G + +++ L + + E A
Sbjct: 378 VCGKTFTLSATLLRH-QRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCG 436
Query: 349 PSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAA 408
S S +I+ + +G+ P + + ++Q ++G
Sbjct: 437 KSFIMSSTLIRH-------QRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCP 489
Query: 409 AHPNDSCHAKTSAPHAQNP------DVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMI 462
+ H + S + + EQ + K + +
Sbjct: 490 ECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGD 549
Query: 463 KKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVK 522
P + G + H C C K F ++H RIH E P+K A A
Sbjct: 550 SLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAP 609
Query: 523 STLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF---RTSG 579
+++ + + S+ + R +P P + F R
Sbjct: 610 KP--------PQLRSPRLPFRGNSYPGA----AEGRAEAPGQPLKPPEGQEGFSQRRGLL 657
Query: 580 HRKTHIASHFKHTELRK---MRHQRKPAKVRVGKTNIPVPDIPLQEPILITD--LGLIQP 634
KT+I SH + L + ++HQ ++P L D +GL +
Sbjct: 658 SSKTYICSHCGESFLDRSVLLQHQLTHGN---------------EKPFLFPDYRIGLGEG 702
Query: 635 IPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPF-KCSQCGRG 693
+ F + +P+KC C +++ S L H + H G K K + G+
Sbjct: 703 AGPSPFL-----------SGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGK- 750
Query: 694 FVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRP 740
S+ VL H+R+ G + ++C C +F +L RH H +P
Sbjct: 751 --SSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKP 795
Score = 122 bits (307), Expect = 2e-27
Identities = 71/197 (36%), Positives = 106/197 (53%), Gaps = 25/197 (12%)
Query: 1613 SPQVILVSHTPQSASAACEEIAYQVAGVSGN---LAPGNQPEK----EGRA------HQC 1659
+P+V+ TP + ACE A + N + P N+P +GR + C
Sbjct: 96 APEVV---PTPSDWTKACEASWQWGALTTWNSPPVVPANEPSLRELVQGRPAGAEKPYIC 152
Query: 1660 LECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKP 1719
EC ++FS + L+ H + +H ER + C C K+F +++HL +H +TH + +KP
Sbjct: 153 NECGKSFSQWSKLLRHQR-IHTGERPNTCSECGKSFTQSSHLVQHQRTH------TGEKP 205
Query: 1720 RVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYK 1779
+KC C K F+ S L +H R HTGE+P+ CT CEKAF Q + L H + HTGE+PYK
Sbjct: 206 --YKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYK 263
Query: 1780 CAYCVMGFTQKSNMKLH 1796
C C F + S++ H
Sbjct: 264 CGECRRAFYRSSDLIQH 280
Score = 116 bits (290), Expect = 2e-25
Identities = 56/144 (38%), Positives = 83/144 (57%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
R + C EC ++F+ ++ L+ H + H E+ + CP C K F +++L +H +TH
Sbjct: 176 RPNTCSECGKSFTQSSHLVQHQR-THTGEKPYKCPDCGKCFSWSSNLVQHQRTH------ 228
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC CEKAF + + L +H R HTGE+P+ C C +AF + S L H HTG
Sbjct: 229 TGEKP--YKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTG 286
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C F Q N+ H K
Sbjct: 287 EKPYKCPECGKRFGQNHNLLKHQK 310
Score = 115 bits (288), Expect = 4e-25
Identities = 56/158 (35%), Positives = 86/158 (54%), Gaps = 9/158 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + + ++C EC++AF+ + L+ H + H E+ + C CR+AF R++
Sbjct: 218 SSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRS-HTGEKPYKCGECRRAFYRSSD 276
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L +H TH + +KP +KC C K F + L +H +IH GE+P+ CT C K+F
Sbjct: 277 LIQHQATH------TGEKP--YKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFI 328
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
Q S L H + HTGE+PY+C C F S + H +
Sbjct: 329 QSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQR 366
Score = 115 bits (288), Expect = 4e-25
Identities = 107/389 (27%), Positives = 141/389 (36%), Gaps = 69/389 (17%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F +SSHL QH R+HTGEKPYKC CG+ F S L +H +TH F
Sbjct: 456 KPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFV 515
Query: 1025 CSVCNASFTTNGSLTRHMATHM---------------------------SMKPYKCPFCE 1057
CS C +F L +H H KP+KC C
Sbjct: 516 CSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCG 575
Query: 1058 EGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASR-KSRPEVITFT 1116
+GF +H + H +A G + + S R R S P
Sbjct: 576 KGFNDEGIFMQHQRIHIGENPYKNADGLI--AHAAPKPPQLRSPRLPFRGNSYPGAAEGR 633
Query: 1117 EEETAQLAKIRP------QESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCT 1170
E Q K Q +S K + S + + D+ LQ + H N
Sbjct: 634 AEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFL----DRSVLLQHQLTHGN--- 686
Query: 1171 YCPKSFKKPSDLVRHVRIHTGE----------KPYKCDECGKSFTVKSTLDCHVKTHTGQ 1220
+KP L RI GE KP+KC EC +SF + S L H K H G
Sbjct: 687 ------EKPF-LFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGG 739
Query: 1221 KLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK 1280
K S + L H+R GA+P++C C F H + H + P
Sbjct: 740 K--SSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPN 797
Query: 1281 ARKP-------MTRSSSEGLQPVNLLNSS 1302
P T EG P +SS
Sbjct: 798 PEDPPPEAVTLSTDQEGEGETPTPTESSS 826
Score = 113 bits (283), Expect = 1e-24
Identities = 58/124 (46%), Positives = 68/124 (54%), Gaps = 3/124 (2%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
C C KSF + S L+RH RIHTGE+P C ECGKSFT S L H +THTG+K + C C
Sbjct: 152 CNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDC 211
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK---ARKPM 1285
FS +L H R HTG KP+KC CE F S H + H P K R+
Sbjct: 212 GKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAF 271
Query: 1286 TRSS 1289
RSS
Sbjct: 272 YRSS 275
Score = 113 bits (282), Expect = 2e-24
Identities = 60/164 (36%), Positives = 85/164 (51%), Gaps = 21/164 (12%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++CLEC ++F ++ L+ H + H RE CPVC K F + L H +TH
Sbjct: 344 KPYECLECGKSFGHSSTLIKHQR-THLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPY 402
Query: 1709 ---QAGPSLSSQK-----------PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
+ G S S R + C C K+F S L RH RIHTGE+P+ C+
Sbjct: 403 KCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSD 462
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
C K+F + S L H + HTGE+PYKC C F+Q SN+ H++
Sbjct: 463 CGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVR 506
Score = 112 bits (279), Expect = 4e-24
Identities = 56/129 (43%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
Query: 1152 LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLD 1211
LR ++ + P N C+ C KSF + S LV+H R HTGEKPYKC +CGK F+ S L
Sbjct: 166 LRHQRIHTGERP---NTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLV 222
Query: 1212 CHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271
H +THTG+K + C C AF+ +L H R HTG KP+KC C F S H
Sbjct: 223 QHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQA 282
Query: 1272 FHYKPDPKK 1280
H P K
Sbjct: 283 THTGEKPYK 291
Score = 106 bits (264), Expect = 2e-22
Identities = 55/160 (34%), Positives = 83/160 (51%), Gaps = 6/160 (3%)
Query: 613 IPVPDIPLQEPILITDLGLIQPIPKNQFFQSY------FNNNFVNEADRPYKCFYCHRAY 666
+P + L+E + G +P N+ +S+ + ++ +RP C C +++
Sbjct: 128 VPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSF 187
Query: 667 KKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGG 726
+S HL QH R+HTGEKP+KC CG+ F + L H RTHTG K +KC C AFT
Sbjct: 188 TQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQST 247
Query: 727 SLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+L +H H +PY C C++ F S + +H TH E
Sbjct: 248 NLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGE 287
Score = 100 bits (249), Expect = 1e-20
Identities = 54/160 (33%), Positives = 79/160 (49%), Gaps = 9/160 (5%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G + NL + + ++C EC ++F ++ L H + H E+ + C C K+F +
Sbjct: 300 GQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQR-THTGEKPYECLECGKSFGHS 358
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+ L +H +TH + FKC C K F + L RH R HTGERP+ C C K+
Sbjct: 359 STLIKHQRTH--------LREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKS 410
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F+ S L H + H GERPY CA C F S + H +
Sbjct: 411 FSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQR 450
Score = 96.7 bits (239), Expect = 2e-19
Identities = 48/142 (33%), Positives = 80/142 (56%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
R ++C EC ++FS ++ L++H + +H ER + C C K+F ++ L H + H
Sbjct: 400 RPYKCPECGKSFSVSSNLINHQR-IHRGERPYICADCGKSFIMSSTLIRHQRIH------ 452
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C K+F + S L +H R HTGE+P+ C C K+F+Q S L H++ H
Sbjct: 453 TGEKP--YKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMD 510
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E + C+ C F + ++ H
Sbjct: 511 ENLFVCSDCGKAFLEAHELEQH 532
Score = 86.3 bits (212), Expect = 3e-16
Identities = 46/102 (45%), Positives = 64/102 (62%), Gaps = 7/102 (6%)
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L+E +Q AG ++KP + C+ C K+F++ S+L RH RIHTGERP C+ C K+F
Sbjct: 135 LRELVQGRPAG----AEKPYI--CNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFT 188
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
Q S L H + HTGE+PYKC C F+ SN+ H +R H+
Sbjct: 189 QSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQH-QRTHT 229
Score = 84.0 bits (206), Expect = 1e-15
Identities = 52/186 (27%), Positives = 83/186 (44%), Gaps = 36/186 (19%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
VS NL + + R + C +C ++F ++ L+ H + +H E+ + C C K+F R++
Sbjct: 413 VSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQR-IHTGEKPYKCSDCGKSFIRSS 471
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
HL +H +TH + +KP +KC C K+F++ S L H R H E F C+ C KAF
Sbjct: 472 HLIQHRRTH------TGEKP--YKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAF 523
Query: 1760 NQKSALQVHMKKH---------------------------TGERPYKCAYCVMGFTQKSN 1792
+ L+ H H G +P+KC C GF +
Sbjct: 524 LEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGI 583
Query: 1793 MKLHMK 1798
H +
Sbjct: 584 FMQHQR 589
Score = 80.9 bits (198), Expect = 1e-14
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 1192 EKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPF 1251
EKPY C+ECGKSF+ S L H + HTG++ +C C +F+ L H R HTG KP+
Sbjct: 147 EKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPY 206
Query: 1252 KCPHCELRFRTSGRRKTHMQFHYKPDPKK---ARKPMTRSSS 1290
KCP C F S H + H P K K T+S++
Sbjct: 207 KCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTN 248
Score = 72.4 bits (176), Expect = 4e-12
Identities = 35/107 (32%), Positives = 52/107 (48%)
Query: 682 EKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPY 741
EKP+ C++CG+ F L H R HTG + C C +FT L +H H +PY
Sbjct: 147 EKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPY 206
Query: 742 MCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQ 788
CP C K F S N +H +TH E + + ++A + + + Q
Sbjct: 207 KCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQ 253
Score = 55.5 bits (132), Expect = 5e-07
Identities = 58/236 (24%), Positives = 86/236 (36%), Gaps = 20/236 (8%)
Query: 987 RSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHM 1046
R K Y C CG F+ VL H+ TH K F + +
Sbjct: 654 RGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAG----PSPFL 709
Query: 1047 SMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASR 1106
S KP+KCP C++ F + H K H S+ + + + +E R
Sbjct: 710 SGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYR 769
Query: 1107 KSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHA 1166
S +F + ++A R QE+ T EK + ++ D++ E + P
Sbjct: 770 CSDCRA-SFLD----RVALTRHQETHT-QEKPPNPEDPPPEAVTLSTDQEGE-GETPTPT 822
Query: 1167 NCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKL 1222
++ + P LV EKPY C ECG FT + L H H G L
Sbjct: 823 ESSSH--GEGQNPKTLVE-------EKPYLCPECGAGFTEVAALLLHRSCHPGVSL 869
Score = 53.9 bits (128), Expect = 1e-06
Identities = 39/147 (26%), Positives = 60/147 (40%), Gaps = 35/147 (23%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRER--------------------IHG----CPV 1690
+ + C C +F +VL+ H HG E+ + G CP
Sbjct: 660 KTYICSHCGESFLDRSVLLQHQL-THGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPE 718
Query: 1691 CRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
C+++F ++ L H + H G S S + P + K S L H R G RP+
Sbjct: 719 CKQSFGLSSELLLHQKVHAGGKS-SQKSPELGKSS---------SVLLEHLRSPLGARPY 768
Query: 1751 HCTLCEKAFNQKSALQVHMKKHTGERP 1777
C+ C +F + AL H + HT E+P
Sbjct: 769 RCSDCRASFLDRVALTRHQETHTQEKP 795
Score = 42.0 bits (97), Expect = 0.006
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 22/195 (11%)
Query: 1591 SQGQQFPALLTDPSLS-GQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQ 1649
+ G + P L D + G+G SP +S P C E Q G+S L +
Sbjct: 683 THGNEKPFLFPDYRIGLGEGAGPSP---FLSGKPFK----CPECK-QSFGLSSELLLHQK 734
Query: 1650 PEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH- 1708
G++ Q + S++VL+ H + G R + C CR +F L H +TH
Sbjct: 735 VHAGGKSSQ--KSPELGKSSSVLLEHLRSPLGA-RPYRCSDCRASFLDRVALTRHQETHT 791
Query: 1709 -QAGPSLSSQKPRVFKCDTCEKAFAK---PSQLERHS-----RIHTGERPFHCTLCEKAF 1759
+ P+ P T ++ + P++ H + E+P+ C C F
Sbjct: 792 QEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKPYLCPECGAGF 851
Query: 1760 NQKSALQVHMKKHTG 1774
+ +AL +H H G
Sbjct: 852 TEVAALLLHRSCHPG 866
Score = 38.5 bits (88), Expect = 0.061
Identities = 55/267 (20%), Positives = 88/267 (32%), Gaps = 90/267 (33%)
Query: 1650 PEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRER---------IHGCPVC------RKA 1694
P + H+CL C + F+ + M H + +H E H P R
Sbjct: 562 PPPGAKPHKCLVCGKGFNDEGIFMQHQR-IHIGENPYKNADGLIAHAAPKPPQLRSPRLP 620
Query: 1695 FK----------RATHLKEHMQTHQAGPSLSSQK----PRVFKCDTCEKAFAKPSQLERH 1740
F+ RA + ++ + S ++ + + C C ++F S L +H
Sbjct: 621 FRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQH 680
Query: 1741 SRIHTGERPF------------------------HCTLCEKAFNQKSALQVHMKKHT--- 1773
H E+PF C C+++F S L +H K H
Sbjct: 681 QLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGK 740
Query: 1774 -----------------------GERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810
G RPY+C+ C F + + H + H+ QE
Sbjct: 741 SSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRH-QETHT-----QEK 794
Query: 1811 AGHPEQDGEELSRTLHLEEVVQEAAGE 1837
+PE E + TL + QE GE
Sbjct: 795 PPNPEDPPPE-AVTLSTD---QEGEGE 817
Score = 35.0 bits (79), Expect = 0.68
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 977 KKSSHLK-QHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
+ SSH + Q+ ++ EKPY C CG GF L H H GV
Sbjct: 823 ESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCHPGV 867
>gi|74027276 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 228 bits (582), Expect = 3e-59
Identities = 161/588 (27%), Positives = 248/588 (42%), Gaps = 52/588 (8%)
Query: 14 HDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQ 73
++ D + L ++ + + ++C C F S F H + + +K C + +
Sbjct: 229 YEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQ-LQSGEKSLTCVERGK 287
Query: 74 TFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQ 133
F L +H+ H GE C C K+FS+ A L+ H +H E+ C +CG F+ +
Sbjct: 288 GFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRR 347
Query: 134 SQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV----SSTRSYNRN 189
S L VH + H E + + C+ C + F +S L++H + H + + +S++RN
Sbjct: 348 SALNVHCKVHTAE----KPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRN 403
Query: 190 --------IDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQ 241
+ Y C CGK F S L H R+HTGE+P+KC ECGK F++ +LQ
Sbjct: 404 SHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQ 463
Query: 242 THMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLN 301
H HTGEK + C C F+ NLQ+H QRVH+ K Y C EC F+
Sbjct: 464 AHQGVHTGEKSYICTVCGKGFTLSSNLQAH-QRVHTGEK---PYKCNECGKSFRRNSHYQ 519
Query: 302 THISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQL 361
H+ +H G + + S + + Q+
Sbjct: 520 VHL-VVHTG--------------------------EKPYKCEICGKGFSQSSYLQIHQKA 552
Query: 362 LELSEPAPVES-GQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420
+ +P E GQ +L I I+ E G A C T
Sbjct: 553 HSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECG-KGFSRRADLKIHCRIHTG 611
Query: 421 APHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVR 480
+ V + ++ ++ E P K ++ K +S L + G +
Sbjct: 612 EKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSF--GRSAHLQAHQKVHTGDK 669
Query: 481 WHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC 540
+ C C K F+ +L H R+HT EKP+KC +C + F+ S+L H HTG K +KC
Sbjct: 670 PYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKC 729
Query: 541 QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
C K FS S L+ H R+HTG +P+ C C K F + H H
Sbjct: 730 DVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 221 bits (562), Expect = 7e-57
Identities = 162/578 (28%), Positives = 242/578 (41%), Gaps = 106/578 (18%)
Query: 466 SPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTL 525
SP LP + G + C C KEF + + L H ++H EKP+KC QC + F+ +S L
Sbjct: 292 SPVLPVHQKVHVGEKLK-CDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSAL 350
Query: 526 TAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHI 585
H K HT K + C+ C ++FS + L+ H RLHTG +PF C C K F R +H+
Sbjct: 351 NVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFS----RNSHL 406
Query: 586 ASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
S HQR
Sbjct: 407 QS-----------HQR-------------------------------------------- 411
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
V+ ++PYKC C + + S +L H R HTGEKP+KC +CG+GF L+AH
Sbjct: 412 ----VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQG 467
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR- 764
HTG KS+ C +C FT +L+ H +H +PY C C K+F+ + + + H+ H
Sbjct: 468 VHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTG 527
Query: 765 ------------YELAQQLQQHQQAASIDDSTVDQ---QSMQASTQMQVE--IESDELPQ 807
+ + LQ HQ+A SI+ + Q S+++Q+ I + E P
Sbjct: 528 EKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPY 587
Query: 808 TAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQ-DPLRGHVDQFE 866
E DL+ + T E +P +E G V Q L H
Sbjct: 588 KCEECGKGFSRRADLKIHCRIHTGE---------KPYNCEECGKVFRQASNLLAHQRVHS 638
Query: 867 EQSPAQQSFEPAGLPQGFTVTDTYHQQPQF-PPVQQLQDSSTLESQALSTSFHQQSLLQA 925
+ P + E G G + HQ+ + + +L+ HQ+
Sbjct: 639 GEKPFK--CEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQR----- 691
Query: 926 PSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQH 985
++ + + + QA Q L + + Y+CD C K F +SS L+ H
Sbjct: 692 -----VHTGEKPYKCGECGKYFSQASSLQ-LHQSVHTGEKPYKCDVCGKVFSRSSQLQSH 745
Query: 986 VRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
R HTGEKPYKC++CG+ F L H + H G K++
Sbjct: 746 QRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSY 783
Score = 210 bits (535), Expect = 9e-54
Identities = 158/634 (24%), Positives = 254/634 (40%), Gaps = 69/634 (10%)
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
S+ + + V+++++ Y+ + K + HTG+K ++C++C + F
Sbjct: 210 SHHDGHRVHKSEKSYRPNDYEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDL 269
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H + +G KS C+ F L H +H + C C K F + + H K
Sbjct: 270 HQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKV 328
Query: 763 HRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDL 822
H E + +Q + S +++ + ++ + E P E L
Sbjct: 329 HVIEKPYKCKQCGKGFS----------RRSALNVHCKVHTAEKPYNCEECGRAFSQASHL 378
Query: 823 EPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQ 882
+ + T E +P + D G ++ H+ + ++ ++ +
Sbjct: 379 QDHQRLHTGE---------KPFKCDACGKSFSRN---SHLQSHQRVHTGEKPYKCEECGK 426
Query: 883 GFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESS 942
GF + + + ++ + + F + S LQA + +
Sbjct: 427 GFICSSNLYIHQRVHTGEK-----PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCG 481
Query: 943 QE-ELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCG 1001
+ L Q Q + E + Y+C+ C K F+++SH + H+ HTGEKPYKC++CG
Sbjct: 482 KGFTLSSNLQAHQRVHTGE----KPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICG 537
Query: 1002 RGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFR 1061
+GF S L+ H+K H+ K F C C F + L H H KPYKC C +GF
Sbjct: 538 KGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFS 597
Query: 1062 TTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEET 1120
K H + H TGE + C + + S+ A ++ F EE
Sbjct: 598 RRADLKIHCRIH---------TGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEEC 648
Query: 1121 AQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQ-AELQDEPKHANCCTYCPKSFKKP 1179
+ R + L+ Q D+P C C K FK
Sbjct: 649 GK----------------------SFGRSAHLQAHQKVHTGDKPYK---CDECGKGFKWS 683
Query: 1180 SDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLK 1239
+L H R+HTGEKPYKC ECGK F+ S+L H HTG+K + C VC FS L+
Sbjct: 684 LNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQ 743
Query: 1240 VHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFH 1273
H R+HTG KP+KC C F H + H
Sbjct: 744 SHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 209 bits (532), Expect = 2e-53
Identities = 148/523 (28%), Positives = 221/523 (42%), Gaps = 55/523 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C F + S H + H +KP+ C++C + F+ +L H+ H+GE P C
Sbjct: 335 YKCKQCGKGFSRRSALNVHCKVHTA-EKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKC 393
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FSR + L++H +H E+ C ECG F S L +H H G + + C
Sbjct: 394 DACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVH----TGEKPYKC 449
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
+ C K F S L+ H H + +Y C CGK F S L H
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEK----------------SYICTVCGKGFTLSSNLQAH 493
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
R+HTGE+P+KC+ECGK+F + Q H++ HTGEKP+ C C FSQ LQ H Q+
Sbjct: 494 QRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIH-QKA 552
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
HS K + C EC F L H +H G A L
Sbjct: 553 HSIEK---PFKCEECGQGFNQSSRLQIH-QLIHTGEKPYKCEECGKGFSRRADL------ 602
Query: 336 QQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQ 395
+ + + + + V +Q L V SG+ P ++ + G + +
Sbjct: 603 -KIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAH 661
Query: 396 ALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLD 455
++G + D C + N D+ ++ E P K
Sbjct: 662 QKVHTG-----DKPYKCDEC--GKGFKWSLNLDMH------------QRVHTGEKPYKCG 702
Query: 456 KKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQC 515
+ K + S L S+ G + + C C K F + S L H R+HT EKP+KC C
Sbjct: 703 ECGKYFSQASSLQLHQSV--HTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEIC 760
Query: 516 FRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIR 558
++F+ +S LT H + H G K++K K+ S K I+
Sbjct: 761 GKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRESTQEKKSIK 803
Score = 202 bits (514), Expect = 2e-51
Identities = 121/368 (32%), Positives = 173/368 (47%), Gaps = 32/368 (8%)
Query: 941 SSQEELDLQAQGSQFLEDNEDQSR-------RSYRCDYCNKGFKKSSHLKQHVRSHTGEK 993
+ ++ A G F ++ QS + Y+C+ C KGF SS+L H R HTGEK
Sbjct: 386 TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEK 445
Query: 994 PYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKC 1053
PYKC+ CG+GF L++H+ HTG K++ C+VC FT + +L H H KPYKC
Sbjct: 446 PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKC 505
Query: 1054 PFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNASRKSRPEV 1112
C + FR H + H+ H TGE +IC + + S +K+
Sbjct: 506 NECGKSFRRNSHYQVHLVVH---------TGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 1113 ITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC---- 1168
F EE Q +S+ + L+ + + + E + D H
Sbjct: 557 KPFKCEECGQGFN----QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGE 612
Query: 1169 ----CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFS 1224
C C K F++ S+L+ H R+H+GEKP+KC+ECGKSF + L H K HTG K +
Sbjct: 613 KPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYK 672
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK---A 1281
C C F +L +H R+HTG KP+KC C F + + H H P K
Sbjct: 673 CDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVC 732
Query: 1282 RKPMTRSS 1289
K +RSS
Sbjct: 733 GKVFSRSS 740
Score = 186 bits (471), Expect = 2e-46
Identities = 153/616 (24%), Positives = 241/616 (39%), Gaps = 95/616 (15%)
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
N ++ +N+ ++ + Y+C C + + H + +GEK C + G+GF +
Sbjct: 233 NMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYS 292
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTF--KTSLN 755
VL H + H G K KC C F+ G L+ H +H +PY C C K F +++LN
Sbjct: 293 PVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALN 351
Query: 756 --CKKHMKTHRYEL---------AQQLQQHQQAASID-----DSTVDQQSMQASTQMQVE 799
CK H Y A LQ HQ+ + + D+ S + Q
Sbjct: 352 VHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQR 411
Query: 800 IESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADE--DGFVAPQDP 857
+ + E P E +L V T E +P + +E GF P
Sbjct: 412 VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGE---------KPYKCEECGKGFSRPSS- 461
Query: 858 LRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTY--HQQPQFPPVQQLQDSSTLESQALST 915
L+ H + ++S+ +GFT++ HQ+ +
Sbjct: 462 LQAH----QGVHTGEKSYICTVCGKGFTLSSNLQAHQRVH-------TGEKPYKCNECGK 510
Query: 916 SFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQF-------LEDNEDQSRRSYR 968
SF + S Q L+ + ++ + G F + + ++
Sbjct: 511 SFRRNSHYQ----------VHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK 560
Query: 969 CDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVC 1028
C+ C +GF +SS L+ H HTGEKPYKC+ CG+GF LK H + HTG K ++C C
Sbjct: 561 CEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEEC 620
Query: 1029 NASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATGETE 1087
F +L H H KP+KC C + F + H + H K H P G+
Sbjct: 621 GKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGF 680
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKD 1147
+ ++ + +P + +Q + ++ +S EK
Sbjct: 681 KWSLNLDMHQ-----RVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEK---------- 725
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
P + C K F + S L H R+HTGEKPYKC+ CGKSF+ +
Sbjct: 726 ---------------PYKCDVC---GKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWR 767
Query: 1208 STLDCHVKTHTGQKLF 1223
S L H + H G K +
Sbjct: 768 SNLTVHHRIHVGDKSY 783
Score = 180 bits (457), Expect = 1e-44
Identities = 105/352 (29%), Positives = 168/352 (47%), Gaps = 37/352 (10%)
Query: 470 PGSIREENGV----RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTL 525
P S++ GV + ++C C K F S+L H R+HT EKP+KC +C ++F S
Sbjct: 459 PSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHY 518
Query: 526 TAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHI 585
H+ HTG K +KC+ C K FS S L++H + H+ +PF C C + F S + H
Sbjct: 519 QVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQ 578
Query: 586 ASH-----FKHTELRKMRHQRKPAKVRV--------------GKTNIPVPDIPL------ 620
H +K E K +R K+ GK ++
Sbjct: 579 LIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHS 638
Query: 621 -QEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSH 679
++P + G + ++ Q++ V+ D+PYKC C + +K S +L H R H
Sbjct: 639 GEKPFKCEECG--KSFGRSAHLQAHQK---VHTGDKPYKCDECGKGFKWSLNLDMHQRVH 693
Query: 680 TGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLR 739
TGEKP+KC +CG+ F A L+ H HTG K +KC +C F+ L+ H +H +
Sbjct: 694 TGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEK 753
Query: 740 PYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQ 791
PY C C K+F N H + H + + + ++ +I +ST +++S++
Sbjct: 754 PYKCEICGKSFSWRSNLTVHHRIHVGD--KSYKSNRGGKNIRESTQEKKSIK 803
Score = 171 bits (432), Expect = 8e-42
Identities = 104/323 (32%), Positives = 140/323 (43%), Gaps = 45/323 (13%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++SY+C+ C K F S H + +GEK C G+GF S VL H+K H G K
Sbjct: 249 QKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-L 307
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRT----TVHCKKHMKRHQTVPSA 1079
C C F+ L H H+ KPYKC C +GF VHCK H
Sbjct: 308 KCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA-------- 359
Query: 1080 VSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E+ ++ R +Q + ++ + EK
Sbjct: 360 ----------------EKPYNCEECGRAF------------SQASHLQDHQRLHTGEKPF 391
Query: 1140 VQSAAEKD--RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
A K R S L+ Q E + C C K F S+L H R+HTGEKPYKC
Sbjct: 392 KCDACGKSFSRNSHLQSHQRVHTGEKPYK--CEECGKGFICSSNLYIHQRVHTGEKPYKC 449
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+ECGK F+ S+L H HTG+K + C VC F+ +L+ H R+HTG KP+KC C
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECG 509
Query: 1258 LRFRTSGRRKTHMQFHYKPDPKK 1280
FR + + H+ H P K
Sbjct: 510 KSFRRNSHYQVHLVVHTGEKPYK 532
Score = 167 bits (423), Expect = 9e-41
Identities = 104/335 (31%), Positives = 141/335 (42%), Gaps = 19/335 (5%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
L +S C KGF S L H + H GEK KC CG+ F L++H+K
Sbjct: 269 LHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQK 327
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQT 1075
H K + C C F+ +L H H + KPY C C F H + H + H
Sbjct: 328 VHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLH-- 385
Query: 1076 VPSAVSATGETE-GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQ----LAKIRPQE 1130
TGE D C + +S + ++ + EE + + + +
Sbjct: 386 -------TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQ 438
Query: 1131 SATVSEKVLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRI 1188
EK K R S L+ Q E + CT C K F S+L H R+
Sbjct: 439 RVHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKSY--ICTVCGKGFTLSSNLQAHQRV 496
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HTGEKPYKC+ECGKSF S H+ HTG+K + C +C FS L++H + H+
Sbjct: 497 HTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
KPFKC C F S R + H H P K +
Sbjct: 557 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEE 591
Score = 159 bits (403), Expect = 2e-38
Identities = 143/597 (23%), Positives = 223/597 (37%), Gaps = 140/597 (23%)
Query: 476 ENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGI 535
++G + C K F L H ++H EK KC +C + F+ + L H K H
Sbjct: 274 QSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKVHVIE 332
Query: 536 KAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595
K +KC+ C K FS +L VH ++HT +P+ C C + F ASH +
Sbjct: 333 KPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQ--------ASHLQD---- 380
Query: 596 KMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADR 655
HQR ++ ++
Sbjct: 381 ---HQR------------------------------------------------LHTGEK 389
Query: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
P+KC C +++ ++ HL+ H R HTGEKP+KC +CG+GF+ + L H R HTG K +KC
Sbjct: 390 PFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKC 449
Query: 716 LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR----------- 764
C F+ SL+ H G+H + Y+C C K F S N + H + H
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECG 509
Query: 765 ------------------------------YELAQQLQQHQQAASIDDSTVDQ---QSMQ 791
+ + LQ HQ+A SI+ + Q
Sbjct: 510 KSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFN 569
Query: 792 ASTQMQVE--IESDELPQTAEVVAANPEAMLDLEPQHVVGT-------EEAG-----LGQ 837
S+++Q+ I + E P E DL+ + T EE G
Sbjct: 570 QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASN 629
Query: 838 QLADQPLEADEDGFVAPQ----DPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVT---DTY 890
LA Q + + E F + H+ ++ + ++ +GF + D +
Sbjct: 630 LLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMH 689
Query: 891 HQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQA 950
+ + + SQA S H QS+ +V ++ SS Q
Sbjct: 690 QRVHTGEKPYKCGECGKYFSQASSLQLH-QSVHTGEKPYKCDVCGKVFSRSS------QL 742
Query: 951 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSS 1007
Q Q + E + Y+C+ C K F S+L H R H G+K YK G+ S
Sbjct: 743 QSHQRVHTGE----KPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRES 795
Score = 126 bits (316), Expect = 2e-28
Identities = 57/142 (40%), Positives = 88/142 (61%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C + FS + L H K VH E+ + C C +AF +A+HL++H + H
Sbjct: 333 KPYKCKQCGKGFSRRSALNVHCK-VHTAEKPYNCEECGRAFSQASHLQDHQRLH------ 385
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP FKCD C K+F++ S L+ H R+HTGE+P+ C C K F S L +H + HTG
Sbjct: 386 TGEKP--FKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTG 443
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C GF++ S+++ H
Sbjct: 444 EKPYKCEECGKGFSRPSSLQAH 465
Score = 123 bits (308), Expect = 2e-27
Identities = 64/157 (40%), Positives = 89/157 (56%), Gaps = 10/157 (6%)
Query: 1646 PGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHM 1705
P +Q G +C EC + FS A L H K VH E+ + C C K F R + L H
Sbjct: 296 PVHQKVHVGEKLKCDECGKEFSQGAHLQTHQK-VHVIEKPYKCKQCGKGFSRRSALNVHC 354
Query: 1706 QTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSAL 1765
+ H A +KP + C+ C +AF++ S L+ H R+HTGE+PF C C K+F++ S L
Sbjct: 355 KVHTA------EKP--YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHL 406
Query: 1766 QVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
Q H + HTGE+PYKC C GF SN+ +H +R H+
Sbjct: 407 QSHQRVHTGEKPYKCEECGKGFICSSNLYIH-QRVHT 442
Score = 119 bits (297), Expect = 4e-26
Identities = 58/148 (39%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC + F A+ L+ H + VH E+ C C K+F R+ HL+ H + H
Sbjct: 613 KPYNCEECGKVFRQASNLLAHQR-VHSGEKPFKCEECGKSFGRSAHLQAHQKVH------ 665
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP +KCD C K F L+ H R+HTGE+P+ C C K F+Q S+LQ+H HTG
Sbjct: 666 TGDKP--YKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTG 723
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F++ S ++ H +R H+
Sbjct: 724 EKPYKCDVCGKVFSRSSQLQSH-QRVHT 750
Score = 118 bits (295), Expect = 6e-26
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 10/167 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V + NL + + +C EC ++F +A L H K VH ++ + C
Sbjct: 617 CEECG-KVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQK-VHTGDKPYKCD 674
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C K FK + +L H + H + +KP +KC C K F++ S L+ H +HTGE+P
Sbjct: 675 ECGKGFKWSLNLDMHQRVH------TGEKP--YKCGECGKYFSQASSLQLHQSVHTGEKP 726
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ C +C K F++ S LQ H + HTGE+PYKC C F+ +SN+ +H
Sbjct: 727 YKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVH 773
Score = 115 bits (288), Expect = 4e-25
Identities = 57/148 (38%), Positives = 81/148 (54%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F ++ L H + VH E+ + C C K F R + L+ H H S
Sbjct: 417 KPYKCEECGKGFICSSNLYIHQR-VHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKS- 474
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ C C K F S L+ H R+HTGE+P+ C C K+F + S QVH+ HTG
Sbjct: 475 -------YICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTG 527
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C GF+Q S +++H K AHS
Sbjct: 528 EKPYKCEICGKGFSQSSYLQIHQK-AHS 554
Score = 115 bits (288), Expect = 4e-25
Identities = 56/156 (35%), Positives = 89/156 (57%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + + ++C EC + FS + L H + VH E+ + C VC K F +++
Sbjct: 431 SSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAH-QGVHTGEKSYICTVCGKGFTLSSN 489
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L+ H + H + +KP +KC+ C K+F + S + H +HTGE+P+ C +C K F+
Sbjct: 490 LQAHQRVH------TGEKP--YKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFS 541
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
Q S LQ+H K H+ E+P+KC C GF Q S +++H
Sbjct: 542 QSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIH 577
Score = 115 bits (287), Expect = 5e-25
Identities = 52/144 (36%), Positives = 88/144 (61%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+++ C C + F+ ++ L H + VH E+ + C C K+F+R +H + H+ H
Sbjct: 473 KSYICTVCGKGFTLSSNLQAHQR-VHTGEKPYKCNECGKSFRRNSHYQVHLVVH------ 525
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ S L+ H + H+ E+PF C C + FNQ S LQ+H HTG
Sbjct: 526 TGEKP--YKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTG 583
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C GF++++++K+H +
Sbjct: 584 EKPYKCEECGKGFSRRADLKIHCR 607
Score = 114 bits (285), Expect = 9e-25
Identities = 63/189 (33%), Positives = 102/189 (53%), Gaps = 15/189 (7%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
+S NL + + ++C EC ++F + H VH E+ + C +C K F +++
Sbjct: 486 LSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLV-VHTGEKPYKCEICGKGFSQSS 544
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
+L+ H + H S +KP FKC+ C + F + S+L+ H IHTGE+P+ C C K F
Sbjct: 545 YLQIHQKAH------SIEKP--FKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGF 596
Query: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGE 1819
++++ L++H + HTGE+PY C C F Q SN+ H +R HS E E+ G+
Sbjct: 597 SRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAH-QRVHS-----GEKPFKCEECGK 650
Query: 1820 ELSRTLHLE 1828
R+ HL+
Sbjct: 651 SFGRSAHLQ 659
Score = 107 bits (267), Expect = 1e-22
Identities = 60/165 (36%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 1134 VSEKVLVQSAAEKDRISELRDKQAELQDEPK-----HANCCTYCPKSFKKPSDLVRHVRI 1188
V +KV V + D + + A LQ K C C K F + S L H ++
Sbjct: 297 VHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKV 356
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HT EKPY C+ECG++F+ S L H + HTG+K F C C +FS L+ H R+HTG
Sbjct: 357 HTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGE 416
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKAR---KPMTRSSS 1290
KP+KC C F S H + H P K K +R SS
Sbjct: 417 KPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSS 461
Score = 105 bits (261), Expect = 5e-22
Identities = 49/144 (34%), Positives = 81/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H K H E+ C C + F +++ L+ H H
Sbjct: 529 KPYKCEICGKGFSQSSYLQIHQK-AHSIEKPFKCEECGQGFNQSSRLQIHQLIH------ 581
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ + L+ H RIHTGE+P++C C K F Q S L H + H+G
Sbjct: 582 TGEKP--YKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSG 639
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+P+KC C F + ++++ H K
Sbjct: 640 EKPFKCEECGKSFGRSAHLQAHQK 663
Score = 100 bits (249), Expect = 1e-20
Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 10/150 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE G S +L + + ++C EC + F + L H + VH E+ + C
Sbjct: 645 CEECGKSF-GRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQR-VHTGEKPYKCG 702
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C K F +A+ L+ H H + +KP +KCD C K F++ SQL+ H R+HTGE+P
Sbjct: 703 ECGKYFSQASSLQLHQSVH------TGEKP--YKCDVCGKVFSRSSQLQSHQRVHTGEKP 754
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYK 1779
+ C +C K+F+ +S L VH + H G++ YK
Sbjct: 755 YKCEICGKSFSWRSNLTVHHRIHVGDKSYK 784
Score = 94.4 bits (233), Expect = 9e-19
Identities = 43/107 (40%), Positives = 61/107 (57%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F ++S L+ H HTGEKPYKC +CG+ F S L+SH++ HTG K +
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYK 756
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMK 1071
C +C SF+ +LT H H+ K YK + R + KK +K
Sbjct: 757 CEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRESTQEKKSIK 803
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Query: 1675 HSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLS----------------SQK 1718
H+ +H ++ + C C+K F + H Q SL+ QK
Sbjct: 241 HNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQK 300
Query: 1719 PRV---FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
V KCD C K F++ + L+ H ++H E+P+ C C K F+++SAL VH K HT E
Sbjct: 301 VHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAE 360
Query: 1776 RPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAA 1835
+PY C C F+Q S+++ H +R H+ E + G+ SR HL+ +
Sbjct: 361 KPYNCEECGRAFSQASHLQDH-QRLHT-----GEKPFKCDACGKSFSRNSHLQSHQRVHT 414
Query: 1836 GE 1837
GE
Sbjct: 415 GE 416
Score = 49.3 bits (116), Expect = 3e-05
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 1704 HMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKS 1763
H H+ S S +P + EK K + +S IHTG++ + C C+K F+ S
Sbjct: 211 HHDGHRVHKSEKSYRPNDY-----EKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLS 265
Query: 1764 ALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSR 1823
+ +H + +GE+ C GF + +H K + G + ++ G+E S+
Sbjct: 266 SFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQK---VHVGEKLKC----DECGKEFSQ 318
Query: 1824 TLHLE 1828
HL+
Sbjct: 319 GAHLQ 323
Score = 38.1 bits (87), Expect = 0.080
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H + VH E+ + C +C K+F ++L H + H S
Sbjct: 725 KPYKCDVCGKVFSRSSQLQSHQR-VHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSY 783
Query: 1715 SSQK 1718
S +
Sbjct: 784 KSNR 787
>gi|74027274 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 228 bits (582), Expect = 3e-59
Identities = 161/588 (27%), Positives = 248/588 (42%), Gaps = 52/588 (8%)
Query: 14 HDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQ 73
++ D + L ++ + + ++C C F S F H + + +K C + +
Sbjct: 229 YEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQ-LQSGEKSLTCVERGK 287
Query: 74 TFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQ 133
F L +H+ H GE C C K+FS+ A L+ H +H E+ C +CG F+ +
Sbjct: 288 GFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRR 347
Query: 134 SQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV----SSTRSYNRN 189
S L VH + H E + + C+ C + F +S L++H + H + + +S++RN
Sbjct: 348 SALNVHCKVHTAE----KPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRN 403
Query: 190 --------IDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQ 241
+ Y C CGK F S L H R+HTGE+P+KC ECGK F++ +LQ
Sbjct: 404 SHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQ 463
Query: 242 THMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLN 301
H HTGEK + C C F+ NLQ+H QRVH+ K Y C EC F+
Sbjct: 464 AHQGVHTGEKSYICTVCGKGFTLSSNLQAH-QRVHTGEK---PYKCNECGKSFRRNSHYQ 519
Query: 302 THISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQL 361
H+ +H G + + S + + Q+
Sbjct: 520 VHL-VVHTG--------------------------EKPYKCEICGKGFSQSSYLQIHQKA 552
Query: 362 LELSEPAPVES-GQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420
+ +P E GQ +L I I+ E G A C T
Sbjct: 553 HSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECG-KGFSRRADLKIHCRIHTG 611
Query: 421 APHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVR 480
+ V + ++ ++ E P K ++ K +S L + G +
Sbjct: 612 EKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSF--GRSAHLQAHQKVHTGDK 669
Query: 481 WHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC 540
+ C C K F+ +L H R+HT EKP+KC +C + F+ S+L H HTG K +KC
Sbjct: 670 PYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKC 729
Query: 541 QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
C K FS S L+ H R+HTG +P+ C C K F + H H
Sbjct: 730 DVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 221 bits (562), Expect = 7e-57
Identities = 162/578 (28%), Positives = 242/578 (41%), Gaps = 106/578 (18%)
Query: 466 SPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTL 525
SP LP + G + C C KEF + + L H ++H EKP+KC QC + F+ +S L
Sbjct: 292 SPVLPVHQKVHVGEKLK-CDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSAL 350
Query: 526 TAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHI 585
H K HT K + C+ C ++FS + L+ H RLHTG +PF C C K F R +H+
Sbjct: 351 NVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFS----RNSHL 406
Query: 586 ASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
S HQR
Sbjct: 407 QS-----------HQR-------------------------------------------- 411
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
V+ ++PYKC C + + S +L H R HTGEKP+KC +CG+GF L+AH
Sbjct: 412 ----VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQG 467
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR- 764
HTG KS+ C +C FT +L+ H +H +PY C C K+F+ + + + H+ H
Sbjct: 468 VHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTG 527
Query: 765 ------------YELAQQLQQHQQAASIDDSTVDQ---QSMQASTQMQVE--IESDELPQ 807
+ + LQ HQ+A SI+ + Q S+++Q+ I + E P
Sbjct: 528 EKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPY 587
Query: 808 TAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQ-DPLRGHVDQFE 866
E DL+ + T E +P +E G V Q L H
Sbjct: 588 KCEECGKGFSRRADLKIHCRIHTGE---------KPYNCEECGKVFRQASNLLAHQRVHS 638
Query: 867 EQSPAQQSFEPAGLPQGFTVTDTYHQQPQF-PPVQQLQDSSTLESQALSTSFHQQSLLQA 925
+ P + E G G + HQ+ + + +L+ HQ+
Sbjct: 639 GEKPFK--CEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQR----- 691
Query: 926 PSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQH 985
++ + + + QA Q L + + Y+CD C K F +SS L+ H
Sbjct: 692 -----VHTGEKPYKCGECGKYFSQASSLQ-LHQSVHTGEKPYKCDVCGKVFSRSSQLQSH 745
Query: 986 VRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
R HTGEKPYKC++CG+ F L H + H G K++
Sbjct: 746 QRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSY 783
Score = 210 bits (535), Expect = 9e-54
Identities = 158/634 (24%), Positives = 254/634 (40%), Gaps = 69/634 (10%)
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
S+ + + V+++++ Y+ + K + HTG+K ++C++C + F
Sbjct: 210 SHHDGHRVHKSEKSYRPNDYEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDL 269
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H + +G KS C+ F L H +H + C C K F + + H K
Sbjct: 270 HQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKV 328
Query: 763 HRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDL 822
H E + +Q + S +++ + ++ + E P E L
Sbjct: 329 HVIEKPYKCKQCGKGFS----------RRSALNVHCKVHTAEKPYNCEECGRAFSQASHL 378
Query: 823 EPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQ 882
+ + T E +P + D G ++ H+ + ++ ++ +
Sbjct: 379 QDHQRLHTGE---------KPFKCDACGKSFSRN---SHLQSHQRVHTGEKPYKCEECGK 426
Query: 883 GFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESS 942
GF + + + ++ + + F + S LQA + +
Sbjct: 427 GFICSSNLYIHQRVHTGEK-----PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCG 481
Query: 943 QE-ELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCG 1001
+ L Q Q + E + Y+C+ C K F+++SH + H+ HTGEKPYKC++CG
Sbjct: 482 KGFTLSSNLQAHQRVHTGE----KPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICG 537
Query: 1002 RGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFR 1061
+GF S L+ H+K H+ K F C C F + L H H KPYKC C +GF
Sbjct: 538 KGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFS 597
Query: 1062 TTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEET 1120
K H + H TGE + C + + S+ A ++ F EE
Sbjct: 598 RRADLKIHCRIH---------TGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEEC 648
Query: 1121 AQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQ-AELQDEPKHANCCTYCPKSFKKP 1179
+ R + L+ Q D+P C C K FK
Sbjct: 649 GK----------------------SFGRSAHLQAHQKVHTGDKPYK---CDECGKGFKWS 683
Query: 1180 SDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLK 1239
+L H R+HTGEKPYKC ECGK F+ S+L H HTG+K + C VC FS L+
Sbjct: 684 LNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQ 743
Query: 1240 VHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFH 1273
H R+HTG KP+KC C F H + H
Sbjct: 744 SHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 209 bits (532), Expect = 2e-53
Identities = 148/523 (28%), Positives = 221/523 (42%), Gaps = 55/523 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C F + S H + H +KP+ C++C + F+ +L H+ H+GE P C
Sbjct: 335 YKCKQCGKGFSRRSALNVHCKVHTA-EKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKC 393
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FSR + L++H +H E+ C ECG F S L +H H G + + C
Sbjct: 394 DACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVH----TGEKPYKC 449
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
+ C K F S L+ H H + +Y C CGK F S L H
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEK----------------SYICTVCGKGFTLSSNLQAH 493
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
R+HTGE+P+KC+ECGK+F + Q H++ HTGEKP+ C C FSQ LQ H Q+
Sbjct: 494 QRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIH-QKA 552
Query: 276 HSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPL 335
HS K + C EC F L H +H G A L
Sbjct: 553 HSIEK---PFKCEECGQGFNQSSRLQIH-QLIHTGEKPYKCEECGKGFSRRADL------ 602
Query: 336 QQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQ 395
+ + + + + V +Q L V SG+ P ++ + G + +
Sbjct: 603 -KIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAH 661
Query: 396 ALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLD 455
++G + D C + N D+ ++ E P K
Sbjct: 662 QKVHTG-----DKPYKCDEC--GKGFKWSLNLDMH------------QRVHTGEKPYKCG 702
Query: 456 KKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQC 515
+ K + S L S+ G + + C C K F + S L H R+HT EKP+KC C
Sbjct: 703 ECGKYFSQASSLQLHQSV--HTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEIC 760
Query: 516 FRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIR 558
++F+ +S LT H + H G K++K K+ S K I+
Sbjct: 761 GKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRESTQEKKSIK 803
Score = 202 bits (514), Expect = 2e-51
Identities = 121/368 (32%), Positives = 173/368 (47%), Gaps = 32/368 (8%)
Query: 941 SSQEELDLQAQGSQFLEDNEDQSR-------RSYRCDYCNKGFKKSSHLKQHVRSHTGEK 993
+ ++ A G F ++ QS + Y+C+ C KGF SS+L H R HTGEK
Sbjct: 386 TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEK 445
Query: 994 PYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKC 1053
PYKC+ CG+GF L++H+ HTG K++ C+VC FT + +L H H KPYKC
Sbjct: 446 PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKC 505
Query: 1054 PFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNASRKSRPEV 1112
C + FR H + H+ H TGE +IC + + S +K+
Sbjct: 506 NECGKSFRRNSHYQVHLVVH---------TGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 1113 ITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC---- 1168
F EE Q +S+ + L+ + + + E + D H
Sbjct: 557 KPFKCEECGQGFN----QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGE 612
Query: 1169 ----CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFS 1224
C C K F++ S+L+ H R+H+GEKP+KC+ECGKSF + L H K HTG K +
Sbjct: 613 KPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYK 672
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK---A 1281
C C F +L +H R+HTG KP+KC C F + + H H P K
Sbjct: 673 CDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVC 732
Query: 1282 RKPMTRSS 1289
K +RSS
Sbjct: 733 GKVFSRSS 740
Score = 186 bits (471), Expect = 2e-46
Identities = 153/616 (24%), Positives = 241/616 (39%), Gaps = 95/616 (15%)
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
N ++ +N+ ++ + Y+C C + + H + +GEK C + G+GF +
Sbjct: 233 NMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYS 292
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTF--KTSLN 755
VL H + H G K KC C F+ G L+ H +H +PY C C K F +++LN
Sbjct: 293 PVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALN 351
Query: 756 --CKKHMKTHRYEL---------AQQLQQHQQAASID-----DSTVDQQSMQASTQMQVE 799
CK H Y A LQ HQ+ + + D+ S + Q
Sbjct: 352 VHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQR 411
Query: 800 IESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADE--DGFVAPQDP 857
+ + E P E +L V T E +P + +E GF P
Sbjct: 412 VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGE---------KPYKCEECGKGFSRPSS- 461
Query: 858 LRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTY--HQQPQFPPVQQLQDSSTLESQALST 915
L+ H + ++S+ +GFT++ HQ+ +
Sbjct: 462 LQAH----QGVHTGEKSYICTVCGKGFTLSSNLQAHQRVH-------TGEKPYKCNECGK 510
Query: 916 SFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQF-------LEDNEDQSRRSYR 968
SF + S Q L+ + ++ + G F + + ++
Sbjct: 511 SFRRNSHYQ----------VHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK 560
Query: 969 CDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVC 1028
C+ C +GF +SS L+ H HTGEKPYKC+ CG+GF LK H + HTG K ++C C
Sbjct: 561 CEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEEC 620
Query: 1029 NASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATGETE 1087
F +L H H KP+KC C + F + H + H K H P G+
Sbjct: 621 GKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGF 680
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKD 1147
+ ++ + +P + +Q + ++ +S EK
Sbjct: 681 KWSLNLDMHQ-----RVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEK---------- 725
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
P + C K F + S L H R+HTGEKPYKC+ CGKSF+ +
Sbjct: 726 ---------------PYKCDVC---GKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWR 767
Query: 1208 STLDCHVKTHTGQKLF 1223
S L H + H G K +
Sbjct: 768 SNLTVHHRIHVGDKSY 783
Score = 180 bits (457), Expect = 1e-44
Identities = 105/352 (29%), Positives = 168/352 (47%), Gaps = 37/352 (10%)
Query: 470 PGSIREENGV----RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTL 525
P S++ GV + ++C C K F S+L H R+HT EKP+KC +C ++F S
Sbjct: 459 PSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHY 518
Query: 526 TAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHI 585
H+ HTG K +KC+ C K FS S L++H + H+ +PF C C + F S + H
Sbjct: 519 QVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQ 578
Query: 586 ASH-----FKHTELRKMRHQRKPAKVRV--------------GKTNIPVPDIPL------ 620
H +K E K +R K+ GK ++
Sbjct: 579 LIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHS 638
Query: 621 -QEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSH 679
++P + G + ++ Q++ V+ D+PYKC C + +K S +L H R H
Sbjct: 639 GEKPFKCEECG--KSFGRSAHLQAHQK---VHTGDKPYKCDECGKGFKWSLNLDMHQRVH 693
Query: 680 TGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLR 739
TGEKP+KC +CG+ F A L+ H HTG K +KC +C F+ L+ H +H +
Sbjct: 694 TGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEK 753
Query: 740 PYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQ 791
PY C C K+F N H + H + + + ++ +I +ST +++S++
Sbjct: 754 PYKCEICGKSFSWRSNLTVHHRIHVGD--KSYKSNRGGKNIRESTQEKKSIK 803
Score = 171 bits (432), Expect = 8e-42
Identities = 104/323 (32%), Positives = 140/323 (43%), Gaps = 45/323 (13%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++SY+C+ C K F S H + +GEK C G+GF S VL H+K H G K
Sbjct: 249 QKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-L 307
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRT----TVHCKKHMKRHQTVPSA 1079
C C F+ L H H+ KPYKC C +GF VHCK H
Sbjct: 308 KCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA-------- 359
Query: 1080 VSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
E+ ++ R +Q + ++ + EK
Sbjct: 360 ----------------EKPYNCEECGRAF------------SQASHLQDHQRLHTGEKPF 391
Query: 1140 VQSAAEKD--RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKC 1197
A K R S L+ Q E + C C K F S+L H R+HTGEKPYKC
Sbjct: 392 KCDACGKSFSRNSHLQSHQRVHTGEKPYK--CEECGKGFICSSNLYIHQRVHTGEKPYKC 449
Query: 1198 DECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCE 1257
+ECGK F+ S+L H HTG+K + C VC F+ +L+ H R+HTG KP+KC C
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECG 509
Query: 1258 LRFRTSGRRKTHMQFHYKPDPKK 1280
FR + + H+ H P K
Sbjct: 510 KSFRRNSHYQVHLVVHTGEKPYK 532
Score = 167 bits (423), Expect = 9e-41
Identities = 104/335 (31%), Positives = 141/335 (42%), Gaps = 19/335 (5%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
L +S C KGF S L H + H GEK KC CG+ F L++H+K
Sbjct: 269 LHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQK 327
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQT 1075
H K + C C F+ +L H H + KPY C C F H + H + H
Sbjct: 328 VHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLH-- 385
Query: 1076 VPSAVSATGETE-GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQ----LAKIRPQE 1130
TGE D C + +S + ++ + EE + + + +
Sbjct: 386 -------TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQ 438
Query: 1131 SATVSEKVLVQSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRI 1188
EK K R S L+ Q E + CT C K F S+L H R+
Sbjct: 439 RVHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKSY--ICTVCGKGFTLSSNLQAHQRV 496
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HTGEKPYKC+ECGKSF S H+ HTG+K + C +C FS L++H + H+
Sbjct: 497 HTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
KPFKC C F S R + H H P K +
Sbjct: 557 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEE 591
Score = 159 bits (403), Expect = 2e-38
Identities = 143/597 (23%), Positives = 223/597 (37%), Gaps = 140/597 (23%)
Query: 476 ENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGI 535
++G + C K F L H ++H EK KC +C + F+ + L H K H
Sbjct: 274 QSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKVHVIE 332
Query: 536 KAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595
K +KC+ C K FS +L VH ++HT +P+ C C + F ASH +
Sbjct: 333 KPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQ--------ASHLQD---- 380
Query: 596 KMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADR 655
HQR ++ ++
Sbjct: 381 ---HQR------------------------------------------------LHTGEK 389
Query: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
P+KC C +++ ++ HL+ H R HTGEKP+KC +CG+GF+ + L H R HTG K +KC
Sbjct: 390 PFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKC 449
Query: 716 LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR----------- 764
C F+ SL+ H G+H + Y+C C K F S N + H + H
Sbjct: 450 EECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECG 509
Query: 765 ------------------------------YELAQQLQQHQQAASIDDSTVDQ---QSMQ 791
+ + LQ HQ+A SI+ + Q
Sbjct: 510 KSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFN 569
Query: 792 ASTQMQVE--IESDELPQTAEVVAANPEAMLDLEPQHVVGT-------EEAG-----LGQ 837
S+++Q+ I + E P E DL+ + T EE G
Sbjct: 570 QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASN 629
Query: 838 QLADQPLEADEDGFVAPQ----DPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVT---DTY 890
LA Q + + E F + H+ ++ + ++ +GF + D +
Sbjct: 630 LLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMH 689
Query: 891 HQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQA 950
+ + + SQA S H QS+ +V ++ SS Q
Sbjct: 690 QRVHTGEKPYKCGECGKYFSQASSLQLH-QSVHTGEKPYKCDVCGKVFSRSS------QL 742
Query: 951 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSS 1007
Q Q + E + Y+C+ C K F S+L H R H G+K YK G+ S
Sbjct: 743 QSHQRVHTGE----KPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRES 795
Score = 126 bits (316), Expect = 2e-28
Identities = 57/142 (40%), Positives = 88/142 (61%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C + FS + L H K VH E+ + C C +AF +A+HL++H + H
Sbjct: 333 KPYKCKQCGKGFSRRSALNVHCK-VHTAEKPYNCEECGRAFSQASHLQDHQRLH------ 385
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP FKCD C K+F++ S L+ H R+HTGE+P+ C C K F S L +H + HTG
Sbjct: 386 TGEKP--FKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTG 443
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C GF++ S+++ H
Sbjct: 444 EKPYKCEECGKGFSRPSSLQAH 465
Score = 123 bits (308), Expect = 2e-27
Identities = 64/157 (40%), Positives = 89/157 (56%), Gaps = 10/157 (6%)
Query: 1646 PGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHM 1705
P +Q G +C EC + FS A L H K VH E+ + C C K F R + L H
Sbjct: 296 PVHQKVHVGEKLKCDECGKEFSQGAHLQTHQK-VHVIEKPYKCKQCGKGFSRRSALNVHC 354
Query: 1706 QTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSAL 1765
+ H A +KP + C+ C +AF++ S L+ H R+HTGE+PF C C K+F++ S L
Sbjct: 355 KVHTA------EKP--YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHL 406
Query: 1766 QVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
Q H + HTGE+PYKC C GF SN+ +H +R H+
Sbjct: 407 QSHQRVHTGEKPYKCEECGKGFICSSNLYIH-QRVHT 442
Score = 119 bits (297), Expect = 4e-26
Identities = 58/148 (39%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C EC + F A+ L+ H + VH E+ C C K+F R+ HL+ H + H
Sbjct: 613 KPYNCEECGKVFRQASNLLAHQR-VHSGEKPFKCEECGKSFGRSAHLQAHQKVH------ 665
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ KP +KCD C K F L+ H R+HTGE+P+ C C K F+Q S+LQ+H HTG
Sbjct: 666 TGDKP--YKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTG 723
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C F++ S ++ H +R H+
Sbjct: 724 EKPYKCDVCGKVFSRSSQLQSH-QRVHT 750
Score = 118 bits (295), Expect = 6e-26
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 10/167 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V + NL + + +C EC ++F +A L H K VH ++ + C
Sbjct: 617 CEECG-KVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQK-VHTGDKPYKCD 674
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C K FK + +L H + H + +KP +KC C K F++ S L+ H +HTGE+P
Sbjct: 675 ECGKGFKWSLNLDMHQRVH------TGEKP--YKCGECGKYFSQASSLQLHQSVHTGEKP 726
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ C +C K F++ S LQ H + HTGE+PYKC C F+ +SN+ +H
Sbjct: 727 YKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVH 773
Score = 115 bits (288), Expect = 4e-25
Identities = 57/148 (38%), Positives = 81/148 (54%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F ++ L H + VH E+ + C C K F R + L+ H H S
Sbjct: 417 KPYKCEECGKGFICSSNLYIHQR-VHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKS- 474
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ C C K F S L+ H R+HTGE+P+ C C K+F + S QVH+ HTG
Sbjct: 475 -------YICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTG 527
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C GF+Q S +++H K AHS
Sbjct: 528 EKPYKCEICGKGFSQSSYLQIHQK-AHS 554
Score = 115 bits (288), Expect = 4e-25
Identities = 56/156 (35%), Positives = 89/156 (57%), Gaps = 9/156 (5%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + + ++C EC + FS + L H + VH E+ + C VC K F +++
Sbjct: 431 SSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAH-QGVHTGEKSYICTVCGKGFTLSSN 489
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L+ H + H + +KP +KC+ C K+F + S + H +HTGE+P+ C +C K F+
Sbjct: 490 LQAHQRVH------TGEKP--YKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFS 541
Query: 1761 QKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
Q S LQ+H K H+ E+P+KC C GF Q S +++H
Sbjct: 542 QSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIH 577
Score = 115 bits (287), Expect = 5e-25
Identities = 52/144 (36%), Positives = 88/144 (61%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+++ C C + F+ ++ L H + VH E+ + C C K+F+R +H + H+ H
Sbjct: 473 KSYICTVCGKGFTLSSNLQAHQR-VHTGEKPYKCNECGKSFRRNSHYQVHLVVH------ 525
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ S L+ H + H+ E+PF C C + FNQ S LQ+H HTG
Sbjct: 526 TGEKP--YKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTG 583
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C GF++++++K+H +
Sbjct: 584 EKPYKCEECGKGFSRRADLKIHCR 607
Score = 114 bits (285), Expect = 9e-25
Identities = 63/189 (33%), Positives = 102/189 (53%), Gaps = 15/189 (7%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
+S NL + + ++C EC ++F + H VH E+ + C +C K F +++
Sbjct: 486 LSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLV-VHTGEKPYKCEICGKGFSQSS 544
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
+L+ H + H S +KP FKC+ C + F + S+L+ H IHTGE+P+ C C K F
Sbjct: 545 YLQIHQKAH------SIEKP--FKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGF 596
Query: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGE 1819
++++ L++H + HTGE+PY C C F Q SN+ H +R HS E E+ G+
Sbjct: 597 SRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAH-QRVHS-----GEKPFKCEECGK 650
Query: 1820 ELSRTLHLE 1828
R+ HL+
Sbjct: 651 SFGRSAHLQ 659
Score = 107 bits (267), Expect = 1e-22
Identities = 60/165 (36%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 1134 VSEKVLVQSAAEKDRISELRDKQAELQDEPK-----HANCCTYCPKSFKKPSDLVRHVRI 1188
V +KV V + D + + A LQ K C C K F + S L H ++
Sbjct: 297 VHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKV 356
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HT EKPY C+ECG++F+ S L H + HTG+K F C C +FS L+ H R+HTG
Sbjct: 357 HTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGE 416
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKAR---KPMTRSSS 1290
KP+KC C F S H + H P K K +R SS
Sbjct: 417 KPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSS 461
Score = 105 bits (261), Expect = 5e-22
Identities = 49/144 (34%), Positives = 81/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H K H E+ C C + F +++ L+ H H
Sbjct: 529 KPYKCEICGKGFSQSSYLQIHQK-AHSIEKPFKCEECGQGFNQSSRLQIHQLIH------ 581
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ + L+ H RIHTGE+P++C C K F Q S L H + H+G
Sbjct: 582 TGEKP--YKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSG 639
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+P+KC C F + ++++ H K
Sbjct: 640 EKPFKCEECGKSFGRSAHLQAHQK 663
Score = 100 bits (249), Expect = 1e-20
Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 10/150 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE G S +L + + ++C EC + F + L H + VH E+ + C
Sbjct: 645 CEECGKSF-GRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQR-VHTGEKPYKCG 702
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C K F +A+ L+ H H + +KP +KCD C K F++ SQL+ H R+HTGE+P
Sbjct: 703 ECGKYFSQASSLQLHQSVH------TGEKP--YKCDVCGKVFSRSSQLQSHQRVHTGEKP 754
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYK 1779
+ C +C K+F+ +S L VH + H G++ YK
Sbjct: 755 YKCEICGKSFSWRSNLTVHHRIHVGDKSYK 784
Score = 94.4 bits (233), Expect = 9e-19
Identities = 43/107 (40%), Positives = 61/107 (57%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F ++S L+ H HTGEKPYKC +CG+ F S L+SH++ HTG K +
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYK 756
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMK 1071
C +C SF+ +LT H H+ K YK + R + KK +K
Sbjct: 757 CEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRESTQEKKSIK 803
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Query: 1675 HSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLS----------------SQK 1718
H+ +H ++ + C C+K F + H Q SL+ QK
Sbjct: 241 HNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQK 300
Query: 1719 PRV---FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
V KCD C K F++ + L+ H ++H E+P+ C C K F+++SAL VH K HT E
Sbjct: 301 VHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAE 360
Query: 1776 RPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEAA 1835
+PY C C F+Q S+++ H +R H+ E + G+ SR HL+ +
Sbjct: 361 KPYNCEECGRAFSQASHLQDH-QRLHT-----GEKPFKCDACGKSFSRNSHLQSHQRVHT 414
Query: 1836 GE 1837
GE
Sbjct: 415 GE 416
Score = 49.3 bits (116), Expect = 3e-05
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 1704 HMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKS 1763
H H+ S S +P + EK K + +S IHTG++ + C C+K F+ S
Sbjct: 211 HHDGHRVHKSEKSYRPNDY-----EKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLS 265
Query: 1764 ALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSR 1823
+ +H + +GE+ C GF + +H K + G + ++ G+E S+
Sbjct: 266 SFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQK---VHVGEKLKC----DECGKEFSQ 318
Query: 1824 TLHLE 1828
HL+
Sbjct: 319 GAHLQ 323
Score = 38.1 bits (87), Expect = 0.080
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H + VH E+ + C +C K+F ++L H + H S
Sbjct: 725 KPYKCDVCGKVFSRSSQLQSHQR-VHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSY 783
Query: 1715 SSQK 1718
S +
Sbjct: 784 KSNR 787
>gi|32698786 zinc finger protein 227 [Homo sapiens]
Length = 799
Score = 223 bits (567), Expect = 2e-57
Identities = 167/594 (28%), Positives = 243/594 (40%), Gaps = 84/594 (14%)
Query: 489 KEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 548
K F + S L H RIH EK +C + F KS+ ++ HTG K+++C C K FS
Sbjct: 276 KCFSQSSHLRTHQRIHPGEKLNRCHESGDCFN-KSSFHSYQSNHTGEKSYRCDSCGKGFS 334
Query: 549 TSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVR- 607
+S L +H R HTG +P+ C C K F S + + H +++ + KP K
Sbjct: 335 SSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCH----------QRVHTEEKPYKCEE 384
Query: 608 VGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYK 667
GK G + +Q V+ ++PYKC C + +
Sbjct: 385 CGK-----------------GFGWSVNLRVHQR---------VHRGEKPYKCEECGKGFT 418
Query: 668 KSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGS 727
++ H H R HTGEKP+KC CG+GF L H R HTG K +KC C FT
Sbjct: 419 QAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTD 478
Query: 728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQ 787
L H +H +PY C C K F + N + H H E + + + S
Sbjct: 479 LHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFS-------- 530
Query: 788 QSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEAD 847
QS + T +V + E P +V + +L+ V+ T E +P + +
Sbjct: 531 QSSKLQTHQRVH--TGEKPYRCDVCGKDFSYSSNLKLHQVIHTGE---------KPYKCE 579
Query: 848 EDGF-VAPQDPLRGH--VDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQD 904
E G + + L H V E+ +Q + F V H
Sbjct: 580 ECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHT-----------G 628
Query: 905 SSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQG----SQFLEDNE 960
+ F Q S LQ+ R+ + D+ +G SQF+
Sbjct: 629 EKPYKCGVCGKGFSQSSGLQSHQ--------RVHTGEKPYKCDVCGKGFRYSSQFIYHQR 680
Query: 961 DQS-RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTG 1019
+ + Y+C+ C KGF +S +L+ H R HTGEKP+ C+ CG+ F L+ H HT
Sbjct: 681 GHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTR 740
Query: 1020 VKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
K F C C F+ + L H H KPYKC C++ FR H K H
Sbjct: 741 EKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVH 794
Score = 214 bits (544), Expect = 8e-55
Identities = 158/565 (27%), Positives = 227/565 (40%), Gaps = 53/565 (9%)
Query: 34 PNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP 93
PN H E C F + S + H R H +K +RC + FN + + ++ H+GE
Sbjct: 269 PNVHTGEKC---FSQSSHLRTHQRIHP-GEKLNRCHESGDCFN-KSSFHSYQSNHTGEKS 323
Query: 94 -TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQ 152
C C K FS L H H E+ C ECG F+ S H H +E +
Sbjct: 324 YRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEE----KP 379
Query: 153 HACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQL 212
+ C+ C K F S L+ H + H R Y C CGK F + +
Sbjct: 380 YKCEECGKGFGWSVNLRVHQRVH----------------RGEKPYKCEECGKGFTQAAHF 423
Query: 213 TRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHV 272
H R+HTGE+P+KC CGK F+ L H HTGEKP+ C C F++ +L H
Sbjct: 424 HIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHF 483
Query: 273 QRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
RVH+ K Y C EC F +L H +H G + + ++ L
Sbjct: 484 -RVHTGEK---PYKCKECGKGFSQASNLQVH-QNVHTGEKRFKCETCGKGFSQSSKL--- 535
Query: 333 LPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDI 392
QT + + L + +G+ P ++ ++
Sbjct: 536 ----QTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSNL 591
Query: 393 LQQALENSGLSSIPAAAHPNDSCHAKTSAPH-----AQNPDVSSVSNEQTDPTDAEQEKE 447
+SG A H + P V + + Q +
Sbjct: 592 HAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQ 651
Query: 448 Q----ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRI 503
+ E P K D K + S F+ R G + + C C K F + +L H R+
Sbjct: 652 RVHTGEKPYKCDVCGKGF-RYSSQFIYHQ-RGHTGEKPYKCEECGKGFGRSLNLRHHQRV 709
Query: 504 HTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGV 563
HT EKP C +C +AF++ S L H+ HT K FKC+ C K FS S L+ H R+HTG
Sbjct: 710 HTGEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGE 769
Query: 564 RPFACPHCDKKF----RTSGHRKTH 584
+P+ C CDK F R + H+K H
Sbjct: 770 KPYKCDICDKDFRHRSRLTYHQKVH 794
Score = 197 bits (501), Expect = 8e-50
Identities = 107/318 (33%), Positives = 147/318 (46%), Gaps = 8/318 (2%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C KGF +++ L H R HTGEKPYKCK CG+GF + L+ H+ HTG K F
Sbjct: 462 KPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFK 521
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C F+ + L H H KPY+C C + F + ++K HQ + +
Sbjct: 522 CETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYS----SNLKLHQVIHTGEKPYK 577
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E G H+ + +P ++ +Q R + EK
Sbjct: 578 CEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVC 637
Query: 1145 EK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + S L+ Q E + C C K F+ S + H R HTGEKPYKC+ECGK
Sbjct: 638 GKGFSQSSGLQSHQRVHTGEKPYK--CDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGK 695
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
F L H + HTG+K C C AFS +L+VH+ +HT K FKC C F
Sbjct: 696 GFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQ 755
Query: 1263 SGRRKTHMQFHYKPDPKK 1280
S R + H + H P K
Sbjct: 756 SARLEAHQRVHTGEKPYK 773
Score = 196 bits (498), Expect = 2e-49
Identities = 159/619 (25%), Positives = 243/619 (39%), Gaps = 121/619 (19%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + H C C + F L H +HT EK F+ S L H + H G K
Sbjct: 246 GEKPHPCGECGRGFSYSPRLPLHPNVHTGEK---------CFSQSSHLRTHQRIHPGEKL 296
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFK-HTELRK 596
+C F+ S S + HTG + + C C K F +S T + H++ HT
Sbjct: 297 NRCHESGDCFNKS-SFHSYQSNHTGEKSYRCDSCGKGFSSS----TGLIIHYRTHTG--- 348
Query: 597 MRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRP 656
++P + G + ++ FQ + V+ ++P
Sbjct: 349 ------------------------EKPYKCEECG--KCFSQSSNFQCHQR---VHTEEKP 379
Query: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716
YKC C + + S +L+ H R H GEKP+KC +CG+GF A H R HTG K +KC
Sbjct: 380 YKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCD 439
Query: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR------------ 764
+C F+ L H +H +PY C C K F + + H + H
Sbjct: 440 VCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGK 499
Query: 765 -YELAQQLQQHQQAASID-----DSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEA 818
+ A LQ HQ + + ++ S + Q + + E P +V +
Sbjct: 500 GFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSY 559
Query: 819 MLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPA 878
+L+ V+ T E +P + +E G
Sbjct: 560 SSNLKLHQVIHTGE---------KPYKCEECG---------------------------- 582
Query: 879 GLPQGFTVTDTYHQQPQFPPVQ---QLQDSSTLESQALSTSFHQQ-SLLQAPSSDGMNVT 934
+GF+ H + + + + SQA+ HQ+ + P G V
Sbjct: 583 ---KGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCG--VC 637
Query: 935 TRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKP 994
+ +SS Q Q + E + Y+CD C KGF+ SS H R HTGEKP
Sbjct: 638 GKGFSQSS------GLQSHQRVHTGE----KPYKCDVCGKGFRYSSQFIYHQRGHTGEKP 687
Query: 995 YKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCP 1054
YKC+ CG+GF S L+ H++ HTG K C C +F+ +L H+ H K +KC
Sbjct: 688 YKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCE 747
Query: 1055 FCEEGFRTTVHCKKHMKRH 1073
C +GF + + H + H
Sbjct: 748 ECGKGFSQSARLEAHQRVH 766
Score = 192 bits (488), Expect = 3e-48
Identities = 106/318 (33%), Positives = 147/318 (46%), Gaps = 36/318 (11%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C KGF S +L+ H R H GEKPYKC+ CG+GF + H++ HTG K +
Sbjct: 378 KPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYK 437
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C VC F+ N L H H KPYKC C +GF H + H TG
Sbjct: 438 CDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVH---------TG 488
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E +P + +Q + ++ ++ EK
Sbjct: 489 E-----------------------KPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCETC 525
Query: 1145 EK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + S+L+ Q E + C C K F S+L H IHTGEKPYKC+ECGK
Sbjct: 526 GKGFSQSSKLQTHQRVHTGEKPYR--CDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGK 583
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
F+ +S L H + H+G+K + C C +FS +VH R+HTG KP+KC C F
Sbjct: 584 GFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQ 643
Query: 1263 SGRRKTHMQFHYKPDPKK 1280
S ++H + H P K
Sbjct: 644 SSGLQSHQRVHTGEKPYK 661
Score = 192 bits (487), Expect = 3e-48
Identities = 105/322 (32%), Positives = 147/322 (45%), Gaps = 32/322 (9%)
Query: 962 QSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVK 1021
+ + Y+C+ C KGF +++H H R HTGEKPYKC +CG+GF + L H + HTG K
Sbjct: 403 RGEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEK 462
Query: 1022 AFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVS 1081
+ C C FT N L H H KPYKC C +GF + + H H
Sbjct: 463 PYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVH-------- 514
Query: 1082 ATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQ 1141
TGE ++ + E + +Q +K++ + EK
Sbjct: 515 -TGE--------------------KRFKCET---CGKGFSQSSKLQTHQRVHTGEKPYRC 550
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
KD K ++ + C C K F S+L H R+H+GEKPYKC++C
Sbjct: 551 DVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCD 610
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
KSF+ H + HTG+K + C VC FS L+ H R+HTG KP+KC C FR
Sbjct: 611 KSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFR 670
Query: 1262 TSGRRKTHMQFHYKPDPKKARK 1283
S + H + H P K +
Sbjct: 671 YSSQFIYHQRGHTGEKPYKCEE 692
Score = 191 bits (485), Expect = 6e-48
Identities = 107/325 (32%), Positives = 149/325 (45%), Gaps = 22/325 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+SYRCD C KGF S+ L H R+HTGEKPYKC+ CG+ F S + H++ HT K +
Sbjct: 322 KSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYK 381
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C F + +L H H KPYKC C +GF H H + H TG
Sbjct: 382 CEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHFHIHQRVH---------TG 432
Query: 1085 ETE-GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E D+C + +S R+ V T + + + + V +
Sbjct: 433 EKPYKCDVCGKGFSHNSPLICHRR----VHTGEKPYKCEACGKGFTRNTDLHIHFRVHTG 488
Query: 1144 AEKDRISELRDKQAELQDEPKHANC--------CTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
+ + E ++ + H N C C K F + S L H R+HTGEKPY
Sbjct: 489 EKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPY 548
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
+CD CGK F+ S L H HTG+K + C C FS + +L H R+H+G KP+KC
Sbjct: 549 RCDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQ 608
Query: 1256 CELRFRTSGRRKTHMQFHYKPDPKK 1280
C+ F + + H + H P K
Sbjct: 609 CDKSFSQAIDFRVHQRVHTGEKPYK 633
Score = 190 bits (482), Expect = 1e-47
Identities = 103/321 (32%), Positives = 149/321 (46%), Gaps = 38/321 (11%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
+ N + ++C+ C KGF +SS L+ H R HTGEKPY+C +CG+ F S LK H+
Sbjct: 509 VHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQV 568
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQT 1075
HTG K + C C F+ +L H H KPYKC C++ F + + H + H
Sbjct: 569 IHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVH-- 626
Query: 1076 VPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVS 1135
TGE +P + +Q + ++ +
Sbjct: 627 -------TGE-----------------------KPYKCGVCGKGFSQSSGLQSHQRVHTG 656
Query: 1136 EKVLVQSAAEKD-RISE--LRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGE 1192
EK K R S + ++ ++P C C K F + +L H R+HTGE
Sbjct: 657 EKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYK---CEECGKGFGRSLNLRHHQRVHTGE 713
Query: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK 1252
KP+ C+ECGK+F++ S L H+ HT +KLF C C FS L+ H R+HTG KP+K
Sbjct: 714 KPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEKPYK 773
Query: 1253 CPHCELRFRTSGRRKTHMQFH 1273
C C+ FR R H + H
Sbjct: 774 CDICDKDFRHRSRLTYHQKVH 794
Score = 184 bits (468), Expect = 5e-46
Identities = 101/308 (32%), Positives = 144/308 (46%), Gaps = 37/308 (12%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + +DL H R+HT EKP+KC +C + F+ S L H HT
Sbjct: 456 RVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHT 515
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTE 593
G K FKC+ C K FS S L+ H R+HTG +P+ C C K F S + K H H
Sbjct: 516 GEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGE-- 573
Query: 594 LRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFN-NNFVNE 652
KP K + K ++S + + V+
Sbjct: 574 --------KPYKC--------------------------EECGKGFSWRSNLHAHQRVHS 599
Query: 653 ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKS 712
++PYKC C +++ ++ + H R HTGEKP+KC CG+GF + L++H R HTG K
Sbjct: 600 GEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKP 659
Query: 713 FKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQ 772
+KC +C F H H +PY C C K F SLN + H + H E +
Sbjct: 660 YKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICE 719
Query: 773 QHQQAASI 780
+ +A S+
Sbjct: 720 ECGKAFSL 727
Score = 169 bits (429), Expect = 2e-41
Identities = 100/316 (31%), Positives = 131/316 (41%), Gaps = 33/316 (10%)
Query: 968 RCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSV 1027
RC F KSS + +HTGEK Y+C CG+GF SS L H +THTG K + C
Sbjct: 298 RCHESGDCFNKSS-FHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEE 356
Query: 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETE 1087
C F+ + + H H KPYKC C +GF +V+ ++ HQ V E
Sbjct: 357 CGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVN----LRVHQRVHRGEKPYKCEE 412
Query: 1088 GGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKD 1147
G + H + +P + + + + EK
Sbjct: 413 CGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYK------- 465
Query: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVK 1207
C C K F + +DL H R+HTGEKPYKC ECGK F+
Sbjct: 466 ---------------------CEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQA 504
Query: 1208 STLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRK 1267
S L H HTG+K F C C FS L+ H R+HTG KP++C C F S K
Sbjct: 505 SNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLK 564
Query: 1268 THMQFHYKPDPKKARK 1283
H H P K +
Sbjct: 565 LHQVIHTGEKPYKCEE 580
Score = 169 bits (429), Expect = 2e-41
Identities = 96/314 (30%), Positives = 147/314 (46%), Gaps = 21/314 (6%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S+ H R+HT EKP+KC +C + F L H + H
Sbjct: 344 RTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHR 403
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH- 588
G K +KC+ C K F+ + +H R+HTG +P+ C C K F + HR+ H
Sbjct: 404 GEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKP 463
Query: 589 ----------FKHTELR---KMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQP 634
++T+L ++ KP K + GK ++ + + + +
Sbjct: 464 YKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCE 523
Query: 635 IPKNQFFQS--YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGR 692
F QS + V+ ++PY+C C + + S +LK H HTGEKP+KC +CG+
Sbjct: 524 TCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGK 583
Query: 693 GFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKT 752
GF L AH R H+G K +KC C+ +F+ R H +H +PY C C K F
Sbjct: 584 GFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQ 643
Query: 753 SLNCKKHMKTHRYE 766
S + H + H E
Sbjct: 644 SSGLQSHQRVHTGE 657
Score = 167 bits (422), Expect = 1e-40
Identities = 159/603 (26%), Positives = 229/603 (37%), Gaps = 84/603 (13%)
Query: 654 DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSF 713
++P+ C C R + S L H HTGEK F S L+ H R H G K
Sbjct: 247 EKPHPCGECGRGFSYSPRLPLHPNVHTGEKCFSQSSH---------LRTHQRIHPGEKLN 297
Query: 714 KCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQ 773
+C F S + H + Y C C K F +S H +TH E + ++
Sbjct: 298 RCHESGDCFNKS-SFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEE 356
Query: 774 HQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGT--- 830
+ S ++ Q + ++E P E ++L V
Sbjct: 357 CGKCFS----------QSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEK 406
Query: 831 ----EEAGLGQQLA------------DQPLEADEDGF-VAPQDPLRGHVDQFEEQSPAQQ 873
EE G G A ++P + D G + PL H + P
Sbjct: 407 PYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKP--- 463
Query: 874 SFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNV 933
++ +GFT H + ++ + + F Q S LQ NV
Sbjct: 464 -YKCEACGKGFTRNTDLHIHFRVHTGEK-----PYKCKECGKGFSQASNLQVHQ----NV 513
Query: 934 TTRLIQESSQEELDLQAQGSQFLEDNEDQSR-------RSYRCDYCNKGFKKSSHLKQHV 986
T ++ + G F + ++ Q+ + YRCD C K F SS+LK H
Sbjct: 514 HT------GEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQ 567
Query: 987 RSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHM 1046
HTGEKPYKC+ CG+GF L +H++ H+G K + C C+ SF+ H H
Sbjct: 568 VIHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHT 627
Query: 1047 SMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGG-DICMEEEEEHSDRNAS 1105
KPYKC C +GF + + H + H TGE D+C + S
Sbjct: 628 GEKPYKCGVCGKGFSQSSGLQSHQRVH---------TGEKPYKCDVCGKGFRYSSQFIYH 678
Query: 1106 RKSRPEVITFTEEETAQ----LAKIRPQESATVSEKVLVQSAAEK--DRISELRDKQAEL 1159
++ + EE + +R + EK + K S LR
Sbjct: 679 QRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVH 738
Query: 1160 QDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTG 1219
E C C K F + + L H R+HTGEKPYKCD C K F +S L H K HTG
Sbjct: 739 TREKLFK--CEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTG 796
Query: 1220 QKL 1222
+KL
Sbjct: 797 KKL 799
Score = 161 bits (408), Expect = 5e-39
Identities = 85/245 (34%), Positives = 119/245 (48%), Gaps = 23/245 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C F S H R H +KP++C+QC ++F+ + +H+ H+GE P C
Sbjct: 576 YKCEECGKGFSWRSNLHAHQRVHS-GEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKC 634
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
VC K FS+ + L++H +H E+ C CG F SQ H H G + + C
Sbjct: 635 GVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGH----TGEKPYKC 690
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
+ C K F S L+ H + H + + C CGK F PS L H
Sbjct: 691 EECGKGFGRSLNLRHHQRVHTGEK----------------PHICEECGKAFSLPSNLRVH 734
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRV 275
+ +HT E+ FKC ECGK F+Q L+ H HTGEKP+ C C F + L H Q+V
Sbjct: 735 LGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYH-QKV 793
Query: 276 HSEVK 280
H+ K
Sbjct: 794 HTGKK 798
Score = 142 bits (359), Expect = 2e-33
Identities = 88/260 (33%), Positives = 126/260 (48%), Gaps = 39/260 (15%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C C K F S+L H R+H+ EKP+KC QC ++F+ H + HTG K
Sbjct: 572 GEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKP 631
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKM 597
+KC C K FS S L+ H R+HTG +P+ C C K FR S S F +
Sbjct: 632 YKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYS--------SQF-------I 676
Query: 598 RHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQS--YFNNNFVNEADR 655
HQR G T ++P + G F +S ++ V+ ++
Sbjct: 677 YHQR-------GHTG--------EKPYKCEECG-------KGFGRSLNLRHHQRVHTGEK 714
Query: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
P+ C C +A+ +L+ H+ HT EK FKC +CG+GF + L+AH R HTG K +KC
Sbjct: 715 PHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKC 774
Query: 716 LICNGAFTTGGSLRRHMGIH 735
IC+ F L H +H
Sbjct: 775 DICDKDFRHRSRLTYHQKVH 794
Score = 140 bits (352), Expect = 1e-32
Identities = 109/402 (27%), Positives = 159/402 (39%), Gaps = 84/402 (20%)
Query: 440 TDAEQEKEQESPEKLDKKEKKMIK----KKSPFLPGSIREENGVRWHVCPYCAKEFRKPS 495
T + + Q +++D K I KKSPF E P E+ K
Sbjct: 181 TYLSESQIQSRGKQIDVKNNLQIHEDFMKKSPF-----HEHIKTDTEPKPCKGNEYGKII 235
Query: 496 DLVRHIRIHTHEKPFKCPQCFRAFAVKSTL---------------TAHIKT--------- 531
+ ++ EKP C +C R F+ L ++H++T
Sbjct: 236 SDGSNQKLPLGEKPHPCGECGRGFSYSPRLPLHPNVHTGEKCFSQSSHLRTHQRIHPGEK 295
Query: 532 ----------------------HTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACP 569
HTG K+++C C K FS+S L +H R HTG +P+ C
Sbjct: 296 LNRCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCE 355
Query: 570 HCDKKFRTSGHRKTHIASH-----FKHTELRK--------MRHQR-----KPAKV-RVGK 610
C K F S + + H H +K E K HQR KP K GK
Sbjct: 356 ECGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGK 415
Query: 611 TNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNN------FVNEADRPYKCFYCHR 664
+ + + + +P + + + +N+ V+ ++PYKC C +
Sbjct: 416 GFTQAAHFHIHQRVHTGE----KPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGK 471
Query: 665 AYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTT 724
+ ++ L H R HTGEKP+KC +CG+GF A L+ H HTG K FKC C F+
Sbjct: 472 GFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQ 531
Query: 725 GGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
L+ H +H +PY C C K F S N K H H E
Sbjct: 532 SSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGE 573
Score = 134 bits (337), Expect = 8e-31
Identities = 93/307 (30%), Positives = 120/307 (39%), Gaps = 68/307 (22%)
Query: 63 DKPHRCDQCPQTFNVEFNLTLHKCTHSGE------------------------------- 91
+KPH C +C + F+ L LH H+GE
Sbjct: 247 EKPHPCGECGRGFSYSPRLPLHPNVHTGEKCFSQSSHLRTHQRIHPGEKLNRCHESGDCF 306
Query: 92 ----------------DPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQ 135
C C K FS L H H E+ C ECG F+ S
Sbjct: 307 NKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSN 366
Query: 136 LAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YKIRVSS---TRSYN 187
H H +E + + C+ C K F S L+ H + H YK T++ +
Sbjct: 367 FQCHQRVHTEE----KPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAH 422
Query: 188 RNIDRSGFT----YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTH 243
+I + T Y C CGK F S L H R+HTGE+P+KC CGK F + L H
Sbjct: 423 FHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIH 482
Query: 244 MIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
HTGEKP+ C C FSQ NLQ H Q VH+ K + C C F L TH
Sbjct: 483 FRVHTGEKPYKCKECGKGFSQASNLQVH-QNVHTGEKR---FKCETCGKGFSQSSKLQTH 538
Query: 304 ISKMHMG 310
++H G
Sbjct: 539 -QRVHTG 544
Score = 121 bits (303), Expect = 7e-27
Identities = 66/191 (34%), Positives = 98/191 (51%), Gaps = 11/191 (5%)
Query: 1607 GQGGAGSPQVILVSHTPQSASA-ACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRA 1665
G+G + S +I+ T CEE + S N + E + ++C EC +
Sbjct: 330 GKGFSSSTGLIIHYRTHTGEKPYKCEECG-KCFSQSSNFQCHQRVHTEEKPYKCEECGKG 388
Query: 1666 FSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCD 1725
F + L H + VH E+ + C C K F +A H H + H + +KP +KCD
Sbjct: 389 FGWSVNLRVHQR-VHRGEKPYKCEECGKGFTQAAHFHIHQRVH------TGEKP--YKCD 439
Query: 1726 TCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVM 1785
C K F+ S L H R+HTGE+P+ C C K F + + L +H + HTGE+PYKC C
Sbjct: 440 VCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGK 499
Query: 1786 GFTQKSNMKLH 1796
GF+Q SN+++H
Sbjct: 500 GFSQASNLQVH 510
Score = 117 bits (292), Expect = 1e-25
Identities = 56/148 (37%), Positives = 86/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + F+ L H + VH E+ + C C K F +A++L+ H H
Sbjct: 462 KPYKCEACGKGFTRNTDLHIHFR-VHTGEKPYKCKECGKGFSQASNLQVHQNVHTG---- 516
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ FKC+TC K F++ S+L+ H R+HTGE+P+ C +C K F+ S L++H HTG
Sbjct: 517 ----EKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTG 572
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C GF+ +SN+ H +R HS
Sbjct: 573 EKPYKCEECGKGFSWRSNLHAH-QRVHS 599
Score = 117 bits (292), Expect = 1e-25
Identities = 56/145 (38%), Positives = 86/145 (59%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C C + FS ++ L H + VH E+ + C VC K F +++LK H H + +
Sbjct: 521 KCETCGKGFSQSSKLQTHQR-VHTGEKPYRCDVCGKDFSYSSNLKLHQVIH------TGE 573
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP +KC+ C K F+ S L H R+H+GE+P+ C C+K+F+Q +VH + HTGE+P
Sbjct: 574 KP--YKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKP 631
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C GF+Q S ++ H +R H+
Sbjct: 632 YKCGVCGKGFSQSSGLQSH-QRVHT 655
Score = 113 bits (282), Expect = 2e-24
Identities = 50/144 (34%), Positives = 82/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS ++ H + VH E+ + C C K F + +L+ H + H+
Sbjct: 350 KPYKCEECGKCFSQSSNFQCHQR-VHTEEKPYKCEECGKGFGWSVNLRVHQRVHRG---- 404
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+KP +KC+ C K F + + H R+HTGE+P+ C +C K F+ S L H + HTG
Sbjct: 405 --EKP--YKCEECGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTG 460
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C GFT+ +++ +H +
Sbjct: 461 EKPYKCEACGKGFTRNTDLHIHFR 484
Score = 112 bits (280), Expect = 3e-24
Identities = 61/183 (33%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H + +H E+ + C C K F ++L H + H
Sbjct: 546 KPYRCDVCGKDFSYSSNLKLH-QVIHTGEKPYKCEECGKGFSWRSNLHAHQRVH------ 598
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP +KC+ C+K+F++ H R+HTGE+P+ C +C K F+Q S LQ H + HTG
Sbjct: 599 SGEKP--YKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTG 656
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+PYKC C GF S H + G E E+ G+ R+L+L +
Sbjct: 657 EKPYKCDVCGKGFRYSSQFIYHQR------GHTGEKPYKCEECGKGFGRSLNLRHHQRVH 710
Query: 1835 AGE 1837
GE
Sbjct: 711 TGE 713
Score = 108 bits (271), Expect = 4e-23
Identities = 70/226 (30%), Positives = 97/226 (42%), Gaps = 29/226 (12%)
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
P ++ ++ S ++ L E+ C ECG F+ +L +H H E
Sbjct: 225 PCKGNEYGKIISDGSNQKLPLGEKPHPCGECGRGFSYSPRLPLHPNVHTGE--------- 275
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGF-----------TYSCPHCGK 204
K F SS L+ H + H +++ ++S F +Y C CGK
Sbjct: 276 ----KCFSQSSHLRTHQRIHPGEKLNRCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGK 331
Query: 205 TFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQ 264
F + L H R HTGE+P+KC ECGK F+Q Q H HT EKP+ C C F
Sbjct: 332 GFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGW 391
Query: 265 KGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
NL+ H QRVH K Y C EC F + H ++H G
Sbjct: 392 SVNLRVH-QRVHRGEK---PYKCEECGKGFTQAAHFHIH-QRVHTG 432
Score = 103 bits (258), Expect = 1e-21
Identities = 49/144 (34%), Positives = 78/144 (54%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + F ++ ++H + H E+ + C C K F R+ +L+ H + H
Sbjct: 658 KPYKCDVCGKGFRYSSQFIYHQRG-HTGEKPYKCEECGKGFGRSLNLRHHQRVH------ 710
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C+ C KAF+ PS L H +HT E+ F C C K F+Q + L+ H + HTG
Sbjct: 711 TGEKPHI--CEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTG 768
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C F +S + H K
Sbjct: 769 EKPYKCDICDKDFRHRSRLTYHQK 792
Score = 102 bits (254), Expect = 3e-21
Identities = 45/122 (36%), Positives = 72/122 (59%), Gaps = 9/122 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + F + L HH + VH E+ H C C KAF ++L+ H+ H
Sbjct: 686 KPYKCEECGKGFGRSLNLRHHQR-VHTGEKPHICEECGKAFSLPSNLRVHLGVHT----- 739
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ ++FKC+ C K F++ ++LE H R+HTGE+P+ C +C+K F +S L H K HTG
Sbjct: 740 ---REKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTG 796
Query: 1775 ER 1776
++
Sbjct: 797 KK 798
Score = 100 bits (249), Expect = 1e-20
Identities = 61/215 (28%), Positives = 87/215 (40%), Gaps = 45/215 (20%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S L H R+HT EKP+KC C + F S H + HT
Sbjct: 624 RVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHT 683
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH----- 588
G K +KC+ C K F S +L+ H R+HTG +P C C K F + + H+ H
Sbjct: 684 GEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTREKL 743
Query: 589 FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNN 648
FK E K Q + +
Sbjct: 744 FKCEECGKGFSQSARLEA----------------------------------------HQ 763
Query: 649 FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
V+ ++PYKC C + ++ L H + HTG+K
Sbjct: 764 RVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTGKK 798
Score = 93.6 bits (231), Expect = 2e-18
Identities = 52/163 (31%), Positives = 77/163 (47%), Gaps = 29/163 (17%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ H C EC R FS + L H VH E K F +++HL+ H + H
Sbjct: 248 KPHPCGECGRGFSYSPRLPLHPN-VHTGE---------KCFSQSSHLRTHQRIHPGEKLN 297
Query: 1709 ---QAGPSLSSQK----------PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLC 1755
++G + + ++CD+C K F+ + L H R HTGE+P+ C C
Sbjct: 298 RCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEEC 357
Query: 1756 EKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
K F+Q S Q H + HT E+PYKC C GF N+++H +
Sbjct: 358 GKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQR 400
Score = 85.9 bits (211), Expect = 3e-16
Identities = 46/121 (38%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
Query: 1163 PKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKL 1222
P H N T K F + S L H RIH GEK +C E G F KS+ + HTG+K
Sbjct: 266 PLHPNVHTG-EKCFSQSSHLRTHQRIHPGEKLNRCHESGDCFN-KSSFHSYQSNHTGEKS 323
Query: 1223 FSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKAR 1282
+ C C FS+ L +H R HTG KP+KC C F S + H + H + P K
Sbjct: 324 YRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCE 383
Query: 1283 K 1283
+
Sbjct: 384 E 384
Score = 75.9 bits (185), Expect = 3e-13
Identities = 58/205 (28%), Positives = 76/205 (37%), Gaps = 59/205 (28%)
Query: 160 KEFETSSELKEHMKTHYKIRVSSTRSY--------NRNIDRSGFTYSCPHCG-------- 203
++F S EH+KT + + Y N+ + + C CG
Sbjct: 205 EDFMKKSPFHEHIKTDTEPKPCKGNEYGKIISDGSNQKLPLGEKPHPCGECGRGFSYSPR 264
Query: 204 -----------KTFQKPSQLTRHIRI---------------------------HTGERPF 225
K F + S L H RI HTGE+ +
Sbjct: 265 LPLHPNVHTGEKCFSQSSHLRTHQRIHPGEKLNRCHESGDCFNKSSFHSYQSNHTGEKSY 324
Query: 226 KCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTY 285
+C CGK F+ L H HTGEKP+ C C FSQ N Q H QRVH+E K Y
Sbjct: 325 RCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCH-QRVHTEEK---PY 380
Query: 286 NCTECSCVFKSLGSLNTHISKMHMG 310
C EC F +L H ++H G
Sbjct: 381 KCEECGKGFGWSVNLRVH-QRVHRG 404
Score = 67.8 bits (164), Expect = 9e-11
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + G S NL + + H C EC +AFS + L H VH RE++ C
Sbjct: 690 CEECG-KGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVH-LGVHTREKLFKCE 747
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER 1748
C K F ++ L+ H + H + +KP +KCD C+K F S+L H ++HTG++
Sbjct: 748 ECGKGFSQSARLEAHQRVH------TGEKP--YKCDICDKDFRHRSRLTYHQKVHTGKK 798
Score = 38.9 bits (89), Expect = 0.047
Identities = 34/163 (20%), Positives = 64/163 (39%), Gaps = 33/163 (20%)
Query: 1662 CDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRV 1721
C + S + + K++ + + + F + + EH++T +P+
Sbjct: 178 CGNTYLSESQIQSRGKQIDVKNNLQ----IHEDFMKKSPFHEHIKT--------DTEPKP 225
Query: 1722 FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCA 1781
K + K + S + ++ GE+P C C + F+ L +H HTGE KC
Sbjct: 226 CKGNEYGKIISDGS----NQKLPLGEKPHPCGECGRGFSYSPRLPLHPNVHTGE---KC- 277
Query: 1782 YCVMGFTQKSNMKLH--------MKRAHSYAGALQESAGHPEQ 1816
F+Q S+++ H + R H +S+ H Q
Sbjct: 278 -----FSQSSHLRTHQRIHPGEKLNRCHESGDCFNKSSFHSYQ 315
>gi|138175847 zinc finger protein 228 isoform 1 [Homo sapiens]
Length = 913
Score = 221 bits (564), Expect = 4e-57
Identities = 170/669 (25%), Positives = 285/669 (42%), Gaps = 84/669 (12%)
Query: 117 KEENLICSECGDEF---TLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMK 173
++EN C +CG++ +L +Q ++ EE + + C +K F S + H +
Sbjct: 227 RKENYSCHDCGEDIMKVSLLNQESIQTEE--------KPYPCTGYRKAFSNDSSSEVHQQ 278
Query: 174 THYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQ-KPSQLTRHIRIHTGERPFKCSECGK 232
H + + + S + + S + + + + S L + R+HT E+P KC E G+
Sbjct: 279 FHLEGKPYTYSSCGKGCNYSSLLHIHQNIEREDDIENSHLKSYQRVHTEEKPCKCGEYGE 338
Query: 233 AFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSE------VKNGPTYN 286
FN L T+ + HTGE + AFS +L S + RVH+ +N +N
Sbjct: 339 NFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLDLNS-IFRVHTRDEPHEYEENENVFN 397
Query: 287 CTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSAS 346
+ C V + + + + + G +S+ + H + + S +
Sbjct: 398 QSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDIQH-------------RVHMEENSYN 444
Query: 347 SQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIP 406
S+ S + +L E QP ++ + + ++ Q + P
Sbjct: 445 SEECGNGFS-LASHFQDLQIVHTKE-----QPYKRYVCSNSFSHNLYLQGHPKIHIGEKP 498
Query: 407 AAAHPNDSCHAKTSAPH-----AQNPDVSSVS----NEQTDPTDAEQEKEQESPEKLDKK 457
H N + H Q P ++ N ++ ++ E P K ++
Sbjct: 499 RKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRVHTGEKPYKCEEC 558
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
+K +S +L R G + + C C K F + S L H R+HT EKP+KC +C +
Sbjct: 559 DKGF--SRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVHTGEKPYKCEECGK 616
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577
F+ S L H + HTG K FKC+ C K FS S +L++H R+HTG +P+ C C K F
Sbjct: 617 GFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSK 676
Query: 578 SGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
+ + HQR V G ++P + G + +
Sbjct: 677 AS---------------TLLAHQR----VHTG-----------EKPYQCDECG--KSFSQ 704
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
+ QS+ + V+ +RPY C C + + + +L+ H R HT KP+KC CG+GF +
Sbjct: 705 RSYLQSHQS---VHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQS 761
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L+AH R HTG K +KC +C F+ L+ H +H + RPY C C K F + +
Sbjct: 762 SRLEAHRRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQ 821
Query: 758 KHMKTHRYE 766
H + H E
Sbjct: 822 AHHRVHTGE 830
Score = 215 bits (548), Expect = 3e-55
Identities = 171/678 (25%), Positives = 265/678 (39%), Gaps = 85/678 (12%)
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF-------- 694
S N + ++PY C +A+ + H + H KP+ S CG+G
Sbjct: 244 SLLNQESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHI 303
Query: 695 ---------VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPY 745
+ LK++ R HT K KC F L + IH Y
Sbjct: 304 HQNIEREDDIENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNI 363
Query: 746 CQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDEL 805
+K F SL+ + H + + ++++ + + Q+ +I ++E
Sbjct: 364 YEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFN----------QSSCLQVHQKIHTEEK 413
Query: 806 PQTAEVVAANPEAMLDLEPQHVV-------GTEEAGLGQQLAD-----QPLEADEDGF-- 851
T + +L+ QH V +EE G G LA Q + E +
Sbjct: 414 LYTDIEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKR 473
Query: 852 ------VAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDS 905
+ L+GH + P ++ GF + + Q+
Sbjct: 474 YVCSNSFSHNLYLQGHPKIHIGEKPRKEH------GNGFNWSSKLKDHQRVHTGQK---- 523
Query: 906 STLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQ---EELDLQAQGSQFLEDNE-- 960
+ F+ +S+L NV R+ EE D S +L+ ++
Sbjct: 524 -PYKCNICGKGFNHRSVL--------NVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRV 574
Query: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
+ Y+C+ C KGF ++S+L+ H R HTGEKPYKC+ CG+GF S L+ H++ HTG
Sbjct: 575 HTGEKPYKCEECGKGFSRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGE 634
Query: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
K F C C F+ + +L H H KPYKC C +GF H + H
Sbjct: 635 KPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVH------- 687
Query: 1081 SATGE-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVS 1135
TGE E G + S ++ RP + + +Q A ++ +
Sbjct: 688 --TGEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTR 745
Query: 1136 EKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
K K R + C C K F + S L H R+H +PY
Sbjct: 746 VKPYKCEMCGKGFSQSSRLEAHRRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPY 805
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
KC++CGK F+ S+L H + HTG+K + C VC FS + +L+ H R+HTG KP+KC
Sbjct: 806 KCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDA 865
Query: 1256 CELRFRTSGRRKTHMQFH 1273
C FR S H + H
Sbjct: 866 CGKGFRWSSGLLIHQRVH 883
Score = 210 bits (534), Expect = 1e-53
Identities = 183/755 (24%), Positives = 285/755 (37%), Gaps = 103/755 (13%)
Query: 35 NFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP- 93
+F KC+ + + H +++ + C C + ++ +L + + E P
Sbjct: 206 HFCKCDSVSWLSHHNDKLEVHRKEN------YSCHDCGEDI-MKVSLLNQESIQTEEKPY 258
Query: 94 TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQH 153
C K FS +S + H H + + S CG S L +H R++
Sbjct: 259 PCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIERED------- 311
Query: 154 ACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSG--FTYSCPHCG-------- 203
+ E +S LK + + H + + Y N + TY H G
Sbjct: 312 -------DIE-NSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNI 363
Query: 204 --KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAA 261
K F L R+HT + P + E FNQ LQ H HT EK + +
Sbjct: 364 YEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKS 423
Query: 262 FSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTET 321
F NL RVH E +YN EC F SL +H + + ++
Sbjct: 424 FICSSNLDIQ-HRVHMEEN---SYNSEECGNGF----SLASHFQDLQI---VHTKEQPYK 472
Query: 322 AHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQ 381
+V + + L LQ + + + +L + V +GQ P
Sbjct: 473 RYVCSNSFSHNLYLQ---GHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNI 529
Query: 382 LSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
G N + + P D +++S A
Sbjct: 530 CG--KGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAH---------------- 571
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
++ E P K ++ K ++ +L G R G + + C C K F + S L H
Sbjct: 572 -QRVHTGEKPYKCEECGKGF--SRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQ 628
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
R+HT EKPFKC +C + F+ L H + HTG K +KC+ C K FS + +L H R+HT
Sbjct: 629 RVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHT 688
Query: 562 GVRPFACPHCDKKFRTSGHRKTHIASHFKH-------------TELRKMRHQRKPAKVRV 608
G +P+ C C K F + ++H + H HQR +V+
Sbjct: 689 GEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKP 748
Query: 609 GKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKK 668
K + G Q + V+ +PYKC C + + +
Sbjct: 749 YKCE-------------MCGKGFSQS-------SRLEAHRRVHTGGKPYKCEVCTKGFSE 788
Query: 669 SCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSL 728
S L+ H R H +P+KC QCG+GF L+AH R HTG K +KC +C F+ +L
Sbjct: 789 SSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNL 848
Query: 729 RRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+ H +H +PY C C K F+ S H + H
Sbjct: 849 QAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVH 883
Score = 187 bits (476), Expect = 6e-47
Identities = 104/306 (33%), Positives = 140/306 (45%), Gaps = 32/306 (10%)
Query: 975 GFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTT 1034
GF SS LK H R HTG+KPYKC +CG+GF VL H++ HTG K + C C+ F+
Sbjct: 505 GFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSR 564
Query: 1035 NGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICME 1094
+ L H H KPYKC C +GF + + H + H TGE
Sbjct: 565 SSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVH---------TGEKP------- 608
Query: 1095 EEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRD 1154
+ E + SR S ++ + EK K
Sbjct: 609 YKCEECGKGFSRSSH----------------LQGHQRVHTGEKPFKCEECGKGFSWSFNL 652
Query: 1155 KQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHV 1214
+ + + C C K F K S L+ H R+HTGEKPY+CDECGKSF+ +S L H
Sbjct: 653 QIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQ 712
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
H+G++ + C VC FS + L+ H R+HT KP+KC C F S R + H + H
Sbjct: 713 SVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHT 772
Query: 1275 KPDPKK 1280
P K
Sbjct: 773 GGKPYK 778
Score = 159 bits (402), Expect = 2e-38
Identities = 144/619 (23%), Positives = 237/619 (38%), Gaps = 99/619 (15%)
Query: 495 SDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLK 554
S L + R+HT EKP KC + F S L + HTG +++ K+FS S L
Sbjct: 316 SHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLDLN 375
Query: 555 VHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP 614
R+HT P + F S + H H + ++ + GK+ I
Sbjct: 376 SIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTE---------EKLYTDIEYGKSFIC 426
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQF-FQSYFNN-NFVNEADRPYKCFYCHRAYKKSCHL 672
++ +Q + + + N F S+F + V+ ++PYK + C ++ + +L
Sbjct: 427 SSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYL 486
Query: 673 --------------------------KQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRT 706
K H R HTG+KP+KC+ CG+GF VL H R
Sbjct: 487 QGHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRV 546
Query: 707 HTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR-- 764
HTG K +KC C+ F+ L+ H +H +PY C C K F + + H + H
Sbjct: 547 HTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVHTGE 606
Query: 765 -----------YELAQQLQQHQQAASIDDSTVDQQ-----SMQASTQMQVEIESDELPQT 808
+ + LQ HQ+ + + ++ S + Q+ + + E P
Sbjct: 607 KPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYK 666
Query: 809 AEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQ 868
E L V T E +P + DE G Q R ++ +
Sbjct: 667 CEECGKGFSKASTLLAHQRVHTGE---------KPYQCDECGKSFSQ---RSYLQSHQSV 714
Query: 869 SPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDS-STLESQALSTSFHQQSLLQAPS 927
++ + +GF+ Q+ Q++ + + F Q S L+A
Sbjct: 715 HSGERPYICEVCGKGFS------QRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHR 768
Query: 928 ---SDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQ---------------------- 962
+ G + + E LQA +E +
Sbjct: 769 RVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHT 828
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y+C+ C KGF + S+L+ H R HTGEKPYKC CG+GF S L H++ H+ K
Sbjct: 829 GEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKF 888
Query: 1023 FSCSVCNASFTTNGSLTRH 1041
+ + ++ +L R+
Sbjct: 889 YKSEDYGKDYPSSENLHRN 907
Score = 145 bits (365), Expect = 5e-34
Identities = 81/229 (35%), Positives = 115/229 (50%), Gaps = 20/229 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C F K S H R H +KP++CD+C ++F+ L H+ HSGE P C
Sbjct: 665 YKCEECGKGFSKASTLLAHQRVHT-GEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYIC 723
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
VC K FS+ A L+ H +H + + C CG F+ S+L E HR+ G + + C
Sbjct: 724 EVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRL----EAHRRVHTGGKPYKC 779
Query: 156 KACKKEFETSSELKEHMKTHYKIR-------------VSSTRSYNRNIDRSGFTYSCPHC 202
+ C K F SS L+ H + H + R SS ++++R + Y C C
Sbjct: 780 EVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHR-VHTGEKPYKCEVC 838
Query: 203 GKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEK 251
GK F + S L H R+HTGE+P+KC CGK F L H H+ +K
Sbjct: 839 GKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDK 887
Score = 133 bits (334), Expect = 2e-30
Identities = 91/321 (28%), Positives = 133/321 (41%), Gaps = 12/321 (3%)
Query: 966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025
SYR + K F S L R HT ++P++ + F S L+ H+K HT K ++
Sbjct: 358 SYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTD 417
Query: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-QTVPSAVSATG 1084
SF + +L HM Y C GF H + H + P
Sbjct: 418 IEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCS 477
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ ++ ++ + RK ++ +K++ + +K +
Sbjct: 478 NSFSHNLYLQGHPKIHIGEKPRKEHGNGFNWS-------SKLKDHQRVHTGQKPYKCNIC 530
Query: 1145 EK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + S L Q E + C C K F + S L H R+HTGEKPYKC+ECGK
Sbjct: 531 GKGFNHRSVLNVHQRVHTGEKPYK--CEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGK 588
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
F+ S L H + HTG+K + C C FS L+ H R+HTG KPFKC C F
Sbjct: 589 GFSRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSW 648
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
S + H + H P K +
Sbjct: 649 SFNLQIHQRVHTGEKPYKCEE 669
Score = 125 bits (314), Expect = 4e-28
Identities = 93/327 (28%), Positives = 136/327 (41%), Gaps = 33/327 (10%)
Query: 978 KSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGS 1037
++SHLK + R HT EKP KC G F L ++E HTG ++ ++ +F+ +
Sbjct: 314 ENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLD 373
Query: 1038 LTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEE 1097
L H +P++ E F + + H K H + E IC
Sbjct: 374 LNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIH--TEEKLYTDIEYGKSFICS---- 427
Query: 1098 EHSDRNASRKSRPEVITFTEEETAQLAKIRP--QESATVSEKVLVQSAAEKDRISELRDK 1155
S+ + + E ++ EE + Q+ V K + ++ S
Sbjct: 428 --SNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTK---EQPYKRYVCSNSFSH 482
Query: 1156 QAELQDEPK----------HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFT 1205
LQ PK H N F S L H R+HTG+KPYKC+ CGK F
Sbjct: 483 NLYLQGHPKIHIGEKPRKEHGN-------GFNWSSKLKDHQRVHTGQKPYKCNICGKGFN 535
Query: 1206 VKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGR 1265
+S L+ H + HTG+K + C C FS L+ H R+HTG KP+KC C F +
Sbjct: 536 HRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSY 595
Query: 1266 RKTHMQFHYKPDPKKAR---KPMTRSS 1289
+ H + H P K K +RSS
Sbjct: 596 LQGHQRVHTGEKPYKCEECGKGFSRSS 622
Score = 124 bits (312), Expect = 6e-28
Identities = 73/252 (28%), Positives = 113/252 (44%), Gaps = 16/252 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C KGF K+S L H R HTGEKPY+C CG+ F L+SH+ H+G + +
Sbjct: 663 KPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYI 722
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C VC F+ L H H +KPYKC C +GF + + H + H G
Sbjct: 723 CEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVH--------TGG 774
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQ----LAKIRPQESATVSEKVLV 1140
+ ++C + E S A ++ E + E+ + + ++ EK
Sbjct: 775 KPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYK 834
Query: 1141 QSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
K + S L+ Q E + C C K F+ S L+ H R+H+ +K YK +
Sbjct: 835 CEVCGKGFSQRSNLQAHQRVHTGEKPYK--CDACGKGFRWSSGLLIHQRVHSSDKFYKSE 892
Query: 1199 ECGKSFTVKSTL 1210
+ GK + L
Sbjct: 893 DYGKDYPSSENL 904
Score = 124 bits (311), Expect = 8e-28
Identities = 64/183 (34%), Positives = 102/183 (55%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C ECD+ FS ++ L H + VH E+ + C C K F R ++L+ H + H
Sbjct: 551 KPYKCEECDKGFSRSSYLQAHQR-VHTGEKPYKCEECGKGFSRNSYLQGHQRVH------ 603
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ S L+ H R+HTGE+PF C C K F+ LQ+H + HTG
Sbjct: 604 TGEKP--YKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTG 661
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+PYKC C GF++ S + H +R H+ E ++ G+ S+ +L+
Sbjct: 662 EKPYKCEECGKGFSKASTLLAH-QRVHT-----GEKPYQCDECGKSFSQRSYLQSHQSVH 715
Query: 1835 AGE 1837
+GE
Sbjct: 716 SGE 718
Score = 120 bits (300), Expect = 2e-26
Identities = 57/148 (38%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H + VH + + C VC K F ++ L+ H + H G
Sbjct: 747 KPYKCEMCGKGFSQSSRLEAH-RRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEG--- 802
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
R +KC+ C K F+ S L+ H R+HTGE+P+ C +C K F+Q+S LQ H + HTG
Sbjct: 803 -----RPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTG 857
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C GF S + +H +R HS
Sbjct: 858 EKPYKCDACGKGFRWSSGLLIH-QRVHS 884
Score = 117 bits (292), Expect = 1e-25
Identities = 50/144 (34%), Positives = 85/144 (59%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS A+ L+ H + VH E+ + C C K+F + ++L+ H H
Sbjct: 663 KPYKCEECGKGFSKASTLLAHQR-VHTGEKPYQCDECGKSFSQRSYLQSHQSVH------ 715
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S ++P + C+ C K F++ + L+ H R+HT +P+ C +C K F+Q S L+ H + HTG
Sbjct: 716 SGERPYI--CEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHTG 773
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
+PYKC C GF++ S ++ H +
Sbjct: 774 GKPYKCEVCTKGFSESSRLQAHQR 797
Score = 116 bits (291), Expect = 2e-25
Identities = 61/170 (35%), Positives = 92/170 (54%), Gaps = 26/170 (15%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++C EC + FS + L H + VH E+ + C C K F R++HL+ H + H
Sbjct: 579 KPYKCEECGKGFSRNSYLQGHQR-VHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPF 637
Query: 1709 ---QAGPSLS-------------SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHC 1752
+ G S +KP +KC+ C K F+K S L H R+HTGE+P+ C
Sbjct: 638 KCEECGKGFSWSFNLQIHQRVHTGEKP--YKCEECGKGFSKASTLLAHQRVHTGEKPYQC 695
Query: 1753 TLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
C K+F+Q+S LQ H H+GERPY C C GF+Q++ ++ H +R H+
Sbjct: 696 DECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGH-QRVHT 744
Score = 112 bits (281), Expect = 3e-24
Identities = 55/145 (37%), Positives = 86/145 (59%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC + FS + L H + VH E+ + C C K F +A+ L H + H + +
Sbjct: 638 KCEECGKGFSWSFNLQIHQR-VHTGEKPYKCEECGKGFSKASTLLAHQRVH------TGE 690
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP ++CD C K+F++ S L+ H +H+GERP+ C +C K F+Q++ LQ H + HT +P
Sbjct: 691 KP--YQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKP 748
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C GF+Q S ++ H +R H+
Sbjct: 749 YKCEMCGKGFSQSSRLEAH-RRVHT 772
Score = 108 bits (271), Expect = 4e-23
Identities = 55/156 (35%), Positives = 88/156 (56%), Gaps = 18/156 (11%)
Query: 1647 GNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQ 1706
G +P KE F+ ++ L H + VH ++ + C +C K F + L H +
Sbjct: 495 GEKPRKEH--------GNGFNWSSKLKDHQR-VHTGQKPYKCNICGKGFNHRSVLNVHQR 545
Query: 1707 THQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQ 1766
H + +KP +KC+ C+K F++ S L+ H R+HTGE+P+ C C K F++ S LQ
Sbjct: 546 VH------TGEKP--YKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQ 597
Query: 1767 VHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
H + HTGE+PYKC C GF++ S+++ H +R H+
Sbjct: 598 GHQRVHTGEKPYKCEECGKGFSRSSHLQGH-QRVHT 632
Score = 101 bits (252), Expect = 6e-21
Identities = 48/124 (38%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S L H R+H +P+KC QC + F+ S+L AH + HT
Sbjct: 769 RVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHT 828
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASHF 589
G K +KC+ C K FS +L+ H R+HTG +P+ C C K FR S H++ H + F
Sbjct: 829 GEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKF 888
Query: 590 KHTE 593
+E
Sbjct: 889 YKSE 892
Score = 97.8 bits (242), Expect = 8e-20
Identities = 90/359 (25%), Positives = 131/359 (36%), Gaps = 53/359 (14%)
Query: 957 EDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKT 1016
+++ + Y C K F S + H + H KPY CG+G S +L H+
Sbjct: 248 QESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQ-- 305
Query: 1017 HTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTV 1076
++ N L + H KP KC E F HC + ++ +
Sbjct: 306 ---------NIEREDDIENSHLKSYQRVHTEEKPCKCGEYGENFN---HCSP-LNTYELI 352
Query: 1077 PSAVSATGETEGGDICMEEEEEHS-DRNASRK--SRPEVITFTEEETA--QLAKIRPQES 1131
TGE E+ HS D N+ + +R E + E E Q + ++ +
Sbjct: 353 H-----TGEMSYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQK 407
Query: 1132 ATVSEKVLVQSAAEKDRI-SELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHT 1190
EK+ K I S D Q + E N C F S +HT
Sbjct: 408 IHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNS-EECGNGFSLASHFQDLQIVHT 466
Query: 1191 GEKPYKCDEC--------------------------GKSFTVKSTLDCHVKTHTGQKLFS 1224
E+PYK C G F S L H + HTGQK +
Sbjct: 467 KEQPYKRYVCSNSFSHNLYLQGHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYK 526
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C++C F+ + L VH R+HTG KP+KC C+ F S + H + H P K +
Sbjct: 527 CNICGKGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEE 585
Score = 90.9 bits (224), Expect = 1e-17
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 9/126 (7%)
Query: 1654 GRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPS 1713
G+ ++C C + FS ++ L H + VH R + C C K F + L+ H + H
Sbjct: 774 GKPYKCEVCTKGFSESSRLQAHQR-VHVEGRPYKCEQCGKGFSGYSSLQAHHRVH----- 827
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
+ +KP +KC+ C K F++ S L+ H R+HTGE+P+ C C K F S L +H + H+
Sbjct: 828 -TGEKP--YKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHS 884
Query: 1774 GERPYK 1779
++ YK
Sbjct: 885 SDKFYK 890
Score = 90.1 bits (222), Expect = 2e-17
Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 6/158 (3%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH-SGEDPTC 95
+KCE+C F + S+ + H R H KP++C+ C + F+ L H+ H G C
Sbjct: 749 YKCEMCGKGFSQSSRLEAHRRVHT-GGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKC 807
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS +SL+AH +H E+ C CG F+ +S L H H G + + C
Sbjct: 808 EQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVH----TGEKPYKC 863
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRS 193
AC K F SS L H + H + + Y ++ S
Sbjct: 864 DACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSS 901
Score = 79.7 bits (195), Expect = 2e-14
Identities = 41/112 (36%), Positives = 58/112 (51%), Gaps = 9/112 (8%)
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
R + C C K F S L H R+HT EKP+KC C + F+ +S L AH + HTG K +K
Sbjct: 803 RPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYK 862
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKH 591
C C K F S L +H R+H+ DK +++ + K + +S H
Sbjct: 863 CDACGKGFRWSSGLLIHQRVHSS---------DKFYKSEDYGKDYPSSENLH 905
Score = 65.5 bits (158), Expect = 5e-10
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S L + EGR ++C +C + FS + L H + VH E+ + C VC K F + ++
Sbjct: 789 SSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHR-VHTGEKPYKCEVCGKGFSQRSN 847
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER 1748
L+ H + H + +KP +KCD C K F S L H R+H+ ++
Sbjct: 848 LQAHQRVH------TGEKP--YKCDACGKGFRWSSGLLIHQRVHSSDK 887
Score = 57.0 bits (136), Expect = 2e-07
Identities = 28/80 (35%), Positives = 42/80 (52%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S+L H R+HT EKP+KC C + F S L H + H+
Sbjct: 825 RVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHS 884
Query: 534 GIKAFKCQYCMKSFSTSGSL 553
K +K + K + +S +L
Sbjct: 885 SDKFYKSEDYGKDYPSSENL 904
Score = 55.1 bits (131), Expect = 6e-07
Identities = 41/172 (23%), Positives = 72/172 (41%), Gaps = 36/172 (20%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSS 1716
H+ E + F+ ++ L H K +H E+++ K+F +++L + H S +S
Sbjct: 387 HEYEENENVFNQSSCLQVHQK-IHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNS 445
Query: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE- 1775
++ C F+ S + +HT E+P+ +C +F+ LQ H K H GE
Sbjct: 446 EE--------CGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYLQGHPKIHIGEK 497
Query: 1776 -------------------------RPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+PYKC C GF +S + +H +R H+
Sbjct: 498 PRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVH-QRVHT 548
Score = 51.6 bits (122), Expect = 7e-06
Identities = 41/154 (26%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 1677 KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQ 1736
+ VH E+ C + F + L + H S ++ + EKAF+
Sbjct: 322 QRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMS--------YRHNIYEKAFSHSLD 373
Query: 1737 LERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
L R+HT + P E FNQ S LQVH K HT E+ Y F SN+ +
Sbjct: 374 LNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDI- 432
Query: 1797 MKRAHSYAGALQESAGHPEQDGEELSRTLHLEEV 1830
R H ++E++ + E+ G S H +++
Sbjct: 433 QHRVH-----MEENSYNSEECGNGFSLASHFQDL 461
Score = 47.8 bits (112), Expect = 1e-04
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 1722 FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCA 1781
+ C C + K S L + S I T E+P+ CT KAF+ S+ +VH + H +PY +
Sbjct: 231 YSCHDCGEDIMKVSLLNQES-IQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYS 289
Query: 1782 YCVMGFTQKSNMKLH 1796
C G S + +H
Sbjct: 290 SCGKGCNYSSLLHIH 304
Score = 46.2 bits (108), Expect = 3e-04
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 36/144 (25%)
Query: 1657 HQCLECDRAFSSAAVLMHHSK--EVHGRERIHGCPVCRKAFKRATHL-KEHMQTHQAGPS 1713
H C +CD S + L HH+ EVH +E + C C + + + L +E +QT +
Sbjct: 206 HFC-KCD----SVSWLSHHNDKLEVHRKEN-YSCHDCGEDIMKVSLLNQESIQTEE---- 255
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHM---- 1769
KP + C KAF+ S E H + H +P+ + C K N S L +H
Sbjct: 256 ----KP--YPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIER 309
Query: 1770 -------------KKHTGERPYKC 1780
+ HT E+P KC
Sbjct: 310 EDDIENSHLKSYQRVHTEEKPCKC 333
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/144 (25%), Positives = 52/144 (36%), Gaps = 18/144 (12%)
Query: 1147 DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTV 1206
D +S L +L+ K C C + K S L+ I T EKPY C K+F+
Sbjct: 211 DSVSWLSHHNDKLEVHRKENYSCHDCGEDIMKVS-LLNQESIQTEEKPYPCTGYRKAFSN 269
Query: 1207 KSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVH-----------------MRLHTGAK 1249
S+ + H + H K ++ C + L +H R+HT K
Sbjct: 270 DSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIEREDDIENSHLKSYQRVHTEEK 329
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
P KC F T+ H
Sbjct: 330 PCKCGEYGENFNHCSPLNTYELIH 353
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 21/137 (15%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP---- 1712
+ C +C ++L S + E+ + C RKAF + + H Q H G
Sbjct: 231 YSCHDCGEDIMKVSLLNQES--IQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTY 288
Query: 1713 ----------SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
SL + + D E S L+ + R+HT E+P C + FN
Sbjct: 289 SSCGKGCNYSSLLHIHQNIEREDDIEN-----SHLKSYQRVHTEEKPCKCGEYGENFNHC 343
Query: 1763 SALQVHMKKHTGERPYK 1779
S L + HTGE Y+
Sbjct: 344 SPLNTYELIHTGEMSYR 360
Score = 42.7 bits (99), Expect = 0.003
Identities = 21/50 (42%), Positives = 30/50 (60%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHE 1014
+ Y+CD C KGF+ SS L H R H+ +K YK + G+ + SS L +E
Sbjct: 859 KPYKCDACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSSENLHRNE 908
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CE+ +G S +L ++ + ++C C + FS + L H + VH E+ + C
Sbjct: 807 CEQCGKGFSGYS-SLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQR-VHTGEKPYKCD 864
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
C K F+ ++ L H + H + S+
Sbjct: 865 ACGKGFRWSSGLLIHQRVHSSDKFYKSE 892
Score = 33.9 bits (76), Expect = 1.5
Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 6/83 (7%)
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
KCD L+ H K + +SCH C K SL + T KP+ C
Sbjct: 209 KCDSVSWLSHHNDKLEVHRKEN-----YSCHDCGEDIM-KVSLLNQESIQTEEKPYPCTG 262
Query: 1256 CELRFRTSGRRKTHMQFHYKPDP 1278
F + H QFH + P
Sbjct: 263 YRKAFSNDSSSEVHQQFHLEGKP 285
>gi|138175821 zinc finger protein 228 isoform 2 [Homo sapiens]
Length = 907
Score = 221 bits (564), Expect = 4e-57
Identities = 170/669 (25%), Positives = 285/669 (42%), Gaps = 84/669 (12%)
Query: 117 KEENLICSECGDEF---TLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMK 173
++EN C +CG++ +L +Q ++ EE + + C +K F S + H +
Sbjct: 221 RKENYSCHDCGEDIMKVSLLNQESIQTEE--------KPYPCTGYRKAFSNDSSSEVHQQ 272
Query: 174 THYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQ-KPSQLTRHIRIHTGERPFKCSECGK 232
H + + + S + + S + + + + S L + R+HT E+P KC E G+
Sbjct: 273 FHLEGKPYTYSSCGKGCNYSSLLHIHQNIEREDDIENSHLKSYQRVHTEEKPCKCGEYGE 332
Query: 233 AFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSE------VKNGPTYN 286
FN L T+ + HTGE + AFS +L S + RVH+ +N +N
Sbjct: 333 NFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLDLNS-IFRVHTRDEPHEYEENENVFN 391
Query: 287 CTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSAS 346
+ C V + + + + + G +S+ + H + + S +
Sbjct: 392 QSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDIQH-------------RVHMEENSYN 438
Query: 347 SQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIP 406
S+ S + +L E QP ++ + + ++ Q + P
Sbjct: 439 SEECGNGFS-LASHFQDLQIVHTKE-----QPYKRYVCSNSFSHNLYLQGHPKIHIGEKP 492
Query: 407 AAAHPNDSCHAKTSAPH-----AQNPDVSSVS----NEQTDPTDAEQEKEQESPEKLDKK 457
H N + H Q P ++ N ++ ++ E P K ++
Sbjct: 493 RKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRVHTGEKPYKCEEC 552
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
+K +S +L R G + + C C K F + S L H R+HT EKP+KC +C +
Sbjct: 553 DKGF--SRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVHTGEKPYKCEECGK 610
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577
F+ S L H + HTG K FKC+ C K FS S +L++H R+HTG +P+ C C K F
Sbjct: 611 GFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSK 670
Query: 578 SGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
+ + HQR V G ++P + G + +
Sbjct: 671 AS---------------TLLAHQR----VHTG-----------EKPYQCDECG--KSFSQ 698
Query: 638 NQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSA 697
+ QS+ + V+ +RPY C C + + + +L+ H R HT KP+KC CG+GF +
Sbjct: 699 RSYLQSHQS---VHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQS 755
Query: 698 GVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK 757
L+AH R HTG K +KC +C F+ L+ H +H + RPY C C K F + +
Sbjct: 756 SRLEAHRRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQ 815
Query: 758 KHMKTHRYE 766
H + H E
Sbjct: 816 AHHRVHTGE 824
Score = 215 bits (548), Expect = 3e-55
Identities = 171/678 (25%), Positives = 265/678 (39%), Gaps = 85/678 (12%)
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGF-------- 694
S N + ++PY C +A+ + H + H KP+ S CG+G
Sbjct: 238 SLLNQESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHI 297
Query: 695 ---------VSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPY 745
+ LK++ R HT K KC F L + IH Y
Sbjct: 298 HQNIEREDDIENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNI 357
Query: 746 CQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDEL 805
+K F SL+ + H + + ++++ + + Q+ +I ++E
Sbjct: 358 YEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFN----------QSSCLQVHQKIHTEEK 407
Query: 806 PQTAEVVAANPEAMLDLEPQHVV-------GTEEAGLGQQLAD-----QPLEADEDGF-- 851
T + +L+ QH V +EE G G LA Q + E +
Sbjct: 408 LYTDIEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKR 467
Query: 852 ------VAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDS 905
+ L+GH + P ++ GF + + Q+
Sbjct: 468 YVCSNSFSHNLYLQGHPKIHIGEKPRKEH------GNGFNWSSKLKDHQRVHTGQK---- 517
Query: 906 STLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQ---EELDLQAQGSQFLEDNE-- 960
+ F+ +S+L NV R+ EE D S +L+ ++
Sbjct: 518 -PYKCNICGKGFNHRSVL--------NVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRV 568
Query: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
+ Y+C+ C KGF ++S+L+ H R HTGEKPYKC+ CG+GF S L+ H++ HTG
Sbjct: 569 HTGEKPYKCEECGKGFSRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGE 628
Query: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
K F C C F+ + +L H H KPYKC C +GF H + H
Sbjct: 629 KPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVH------- 681
Query: 1081 SATGE-----TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVS 1135
TGE E G + S ++ RP + + +Q A ++ +
Sbjct: 682 --TGEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTR 739
Query: 1136 EKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
K K R + C C K F + S L H R+H +PY
Sbjct: 740 VKPYKCEMCGKGFSQSSRLEAHRRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPY 799
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
KC++CGK F+ S+L H + HTG+K + C VC FS + +L+ H R+HTG KP+KC
Sbjct: 800 KCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDA 859
Query: 1256 CELRFRTSGRRKTHMQFH 1273
C FR S H + H
Sbjct: 860 CGKGFRWSSGLLIHQRVH 877
Score = 210 bits (534), Expect = 1e-53
Identities = 183/755 (24%), Positives = 285/755 (37%), Gaps = 103/755 (13%)
Query: 35 NFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP- 93
+F KC+ + + H +++ + C C + ++ +L + + E P
Sbjct: 200 HFCKCDSVSWLSHHNDKLEVHRKEN------YSCHDCGEDI-MKVSLLNQESIQTEEKPY 252
Query: 94 TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQH 153
C K FS +S + H H + + S CG S L +H R++
Sbjct: 253 PCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIERED------- 305
Query: 154 ACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSG--FTYSCPHCG-------- 203
+ E +S LK + + H + + Y N + TY H G
Sbjct: 306 -------DIE-NSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNI 357
Query: 204 --KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAA 261
K F L R+HT + P + E FNQ LQ H HT EK + +
Sbjct: 358 YEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKS 417
Query: 262 FSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTET 321
F NL RVH E +YN EC F SL +H + + ++
Sbjct: 418 FICSSNLDIQ-HRVHMEEN---SYNSEECGNGF----SLASHFQDLQI---VHTKEQPYK 466
Query: 322 AHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQ 381
+V + + L LQ + + + +L + V +GQ P
Sbjct: 467 RYVCSNSFSHNLYLQ---GHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNI 523
Query: 382 LSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
G N + + P D +++S A
Sbjct: 524 CG--KGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAH---------------- 565
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
++ E P K ++ K ++ +L G R G + + C C K F + S L H
Sbjct: 566 -QRVHTGEKPYKCEECGKGF--SRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQ 622
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
R+HT EKPFKC +C + F+ L H + HTG K +KC+ C K FS + +L H R+HT
Sbjct: 623 RVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHT 682
Query: 562 GVRPFACPHCDKKFRTSGHRKTHIASHFKH-------------TELRKMRHQRKPAKVRV 608
G +P+ C C K F + ++H + H HQR +V+
Sbjct: 683 GEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKP 742
Query: 609 GKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKK 668
K + G Q + V+ +PYKC C + + +
Sbjct: 743 YKCE-------------MCGKGFSQS-------SRLEAHRRVHTGGKPYKCEVCTKGFSE 782
Query: 669 SCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSL 728
S L+ H R H +P+KC QCG+GF L+AH R HTG K +KC +C F+ +L
Sbjct: 783 SSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNL 842
Query: 729 RRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTH 763
+ H +H +PY C C K F+ S H + H
Sbjct: 843 QAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVH 877
Score = 187 bits (476), Expect = 6e-47
Identities = 104/306 (33%), Positives = 140/306 (45%), Gaps = 32/306 (10%)
Query: 975 GFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTT 1034
GF SS LK H R HTG+KPYKC +CG+GF VL H++ HTG K + C C+ F+
Sbjct: 499 GFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSR 558
Query: 1035 NGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICME 1094
+ L H H KPYKC C +GF + + H + H TGE
Sbjct: 559 SSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVH---------TGEKP------- 602
Query: 1095 EEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRD 1154
+ E + SR S ++ + EK K
Sbjct: 603 YKCEECGKGFSRSSH----------------LQGHQRVHTGEKPFKCEECGKGFSWSFNL 646
Query: 1155 KQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHV 1214
+ + + C C K F K S L+ H R+HTGEKPY+CDECGKSF+ +S L H
Sbjct: 647 QIHQRVHTGEKPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQ 706
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
H+G++ + C VC FS + L+ H R+HT KP+KC C F S R + H + H
Sbjct: 707 SVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHT 766
Query: 1275 KPDPKK 1280
P K
Sbjct: 767 GGKPYK 772
Score = 159 bits (402), Expect = 2e-38
Identities = 144/619 (23%), Positives = 237/619 (38%), Gaps = 99/619 (15%)
Query: 495 SDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLK 554
S L + R+HT EKP KC + F S L + HTG +++ K+FS S L
Sbjct: 310 SHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLDLN 369
Query: 555 VHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIP 614
R+HT P + F S + H H + ++ + GK+ I
Sbjct: 370 SIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTE---------EKLYTDIEYGKSFIC 420
Query: 615 VPDIPLQEPILITDLGLIQPIPKNQF-FQSYFNN-NFVNEADRPYKCFYCHRAYKKSCHL 672
++ +Q + + + N F S+F + V+ ++PYK + C ++ + +L
Sbjct: 421 SSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYL 480
Query: 673 --------------------------KQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRT 706
K H R HTG+KP+KC+ CG+GF VL H R
Sbjct: 481 QGHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVHQRV 540
Query: 707 HTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR-- 764
HTG K +KC C+ F+ L+ H +H +PY C C K F + + H + H
Sbjct: 541 HTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQGHQRVHTGE 600
Query: 765 -----------YELAQQLQQHQQAASIDDSTVDQQ-----SMQASTQMQVEIESDELPQT 808
+ + LQ HQ+ + + ++ S + Q+ + + E P
Sbjct: 601 KPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTGEKPYK 660
Query: 809 AEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQ 868
E L V T E +P + DE G Q R ++ +
Sbjct: 661 CEECGKGFSKASTLLAHQRVHTGE---------KPYQCDECGKSFSQ---RSYLQSHQSV 708
Query: 869 SPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDS-STLESQALSTSFHQQSLLQAPS 927
++ + +GF+ Q+ Q++ + + F Q S L+A
Sbjct: 709 HSGERPYICEVCGKGFS------QRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHR 762
Query: 928 ---SDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQ---------------------- 962
+ G + + E LQA +E +
Sbjct: 763 RVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHT 822
Query: 963 SRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y+C+ C KGF + S+L+ H R HTGEKPYKC CG+GF S L H++ H+ K
Sbjct: 823 GEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKF 882
Query: 1023 FSCSVCNASFTTNGSLTRH 1041
+ + ++ +L R+
Sbjct: 883 YKSEDYGKDYPSSENLHRN 901
Score = 145 bits (365), Expect = 5e-34
Identities = 81/229 (35%), Positives = 115/229 (50%), Gaps = 20/229 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C F K S H R H +KP++CD+C ++F+ L H+ HSGE P C
Sbjct: 659 YKCEECGKGFSKASTLLAHQRVHT-GEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYIC 717
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
VC K FS+ A L+ H +H + + C CG F+ S+L E HR+ G + + C
Sbjct: 718 EVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRL----EAHRRVHTGGKPYKC 773
Query: 156 KACKKEFETSSELKEHMKTHYKIR-------------VSSTRSYNRNIDRSGFTYSCPHC 202
+ C K F SS L+ H + H + R SS ++++R + Y C C
Sbjct: 774 EVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHR-VHTGEKPYKCEVC 832
Query: 203 GKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEK 251
GK F + S L H R+HTGE+P+KC CGK F L H H+ +K
Sbjct: 833 GKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDK 881
Score = 133 bits (334), Expect = 2e-30
Identities = 91/321 (28%), Positives = 133/321 (41%), Gaps = 12/321 (3%)
Query: 966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025
SYR + K F S L R HT ++P++ + F S L+ H+K HT K ++
Sbjct: 352 SYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTD 411
Query: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-QTVPSAVSATG 1084
SF + +L HM Y C GF H + H + P
Sbjct: 412 IEYGKSFICSSNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTKEQPYKRYVCS 471
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
+ ++ ++ + RK ++ +K++ + +K +
Sbjct: 472 NSFSHNLYLQGHPKIHIGEKPRKEHGNGFNWS-------SKLKDHQRVHTGQKPYKCNIC 524
Query: 1145 EK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGK 1202
K + S L Q E + C C K F + S L H R+HTGEKPYKC+ECGK
Sbjct: 525 GKGFNHRSVLNVHQRVHTGEKPYK--CEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGK 582
Query: 1203 SFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262
F+ S L H + HTG+K + C C FS L+ H R+HTG KPFKC C F
Sbjct: 583 GFSRNSYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSW 642
Query: 1263 SGRRKTHMQFHYKPDPKKARK 1283
S + H + H P K +
Sbjct: 643 SFNLQIHQRVHTGEKPYKCEE 663
Score = 125 bits (314), Expect = 4e-28
Identities = 93/327 (28%), Positives = 136/327 (41%), Gaps = 33/327 (10%)
Query: 978 KSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGS 1037
++SHLK + R HT EKP KC G F L ++E HTG ++ ++ +F+ +
Sbjct: 308 ENSHLKSYQRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMSYRHNIYEKAFSHSLD 367
Query: 1038 LTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEE 1097
L H +P++ E F + + H K H + E IC
Sbjct: 368 LNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIH--TEEKLYTDIEYGKSFICS---- 421
Query: 1098 EHSDRNASRKSRPEVITFTEEETAQLAKIRP--QESATVSEKVLVQSAAEKDRISELRDK 1155
S+ + + E ++ EE + Q+ V K + ++ S
Sbjct: 422 --SNLDIQHRVHMEENSYNSEECGNGFSLASHFQDLQIVHTK---EQPYKRYVCSNSFSH 476
Query: 1156 QAELQDEPK----------HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFT 1205
LQ PK H N F S L H R+HTG+KPYKC+ CGK F
Sbjct: 477 NLYLQGHPKIHIGEKPRKEHGN-------GFNWSSKLKDHQRVHTGQKPYKCNICGKGFN 529
Query: 1206 VKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGR 1265
+S L+ H + HTG+K + C C FS L+ H R+HTG KP+KC C F +
Sbjct: 530 HRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSY 589
Query: 1266 RKTHMQFHYKPDPKKAR---KPMTRSS 1289
+ H + H P K K +RSS
Sbjct: 590 LQGHQRVHTGEKPYKCEECGKGFSRSS 616
Score = 124 bits (312), Expect = 6e-28
Identities = 73/252 (28%), Positives = 113/252 (44%), Gaps = 16/252 (6%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C KGF K+S L H R HTGEKPY+C CG+ F L+SH+ H+G + +
Sbjct: 657 KPYKCEECGKGFSKASTLLAHQRVHTGEKPYQCDECGKSFSQRSYLQSHQSVHSGERPYI 716
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C VC F+ L H H +KPYKC C +GF + + H + H G
Sbjct: 717 CEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVH--------TGG 768
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQ----LAKIRPQESATVSEKVLV 1140
+ ++C + E S A ++ E + E+ + + ++ EK
Sbjct: 769 KPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYK 828
Query: 1141 QSAAEK--DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
K + S L+ Q E + C C K F+ S L+ H R+H+ +K YK +
Sbjct: 829 CEVCGKGFSQRSNLQAHQRVHTGEKPYK--CDACGKGFRWSSGLLIHQRVHSSDKFYKSE 886
Query: 1199 ECGKSFTVKSTL 1210
+ GK + L
Sbjct: 887 DYGKDYPSSENL 898
Score = 124 bits (311), Expect = 8e-28
Identities = 64/183 (34%), Positives = 102/183 (55%), Gaps = 15/183 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C ECD+ FS ++ L H + VH E+ + C C K F R ++L+ H + H
Sbjct: 545 KPYKCEECDKGFSRSSYLQAHQR-VHTGEKPYKCEECGKGFSRNSYLQGHQRVH------ 597
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F++ S L+ H R+HTGE+PF C C K F+ LQ+H + HTG
Sbjct: 598 TGEKP--YKCEECGKGFSRSSHLQGHQRVHTGEKPFKCEECGKGFSWSFNLQIHQRVHTG 655
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+PYKC C GF++ S + H +R H+ E ++ G+ S+ +L+
Sbjct: 656 EKPYKCEECGKGFSKASTLLAH-QRVHT-----GEKPYQCDECGKSFSQRSYLQSHQSVH 709
Query: 1835 AGE 1837
+GE
Sbjct: 710 SGE 712
Score = 120 bits (300), Expect = 2e-26
Identities = 57/148 (38%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C + FS ++ L H + VH + + C VC K F ++ L+ H + H G
Sbjct: 741 KPYKCEMCGKGFSQSSRLEAH-RRVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEG--- 796
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
R +KC+ C K F+ S L+ H R+HTGE+P+ C +C K F+Q+S LQ H + HTG
Sbjct: 797 -----RPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTG 851
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PYKC C GF S + +H +R HS
Sbjct: 852 EKPYKCDACGKGFRWSSGLLIH-QRVHS 878
Score = 117 bits (292), Expect = 1e-25
Identities = 50/144 (34%), Positives = 85/144 (59%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FS A+ L+ H + VH E+ + C C K+F + ++L+ H H
Sbjct: 657 KPYKCEECGKGFSKASTLLAHQR-VHTGEKPYQCDECGKSFSQRSYLQSHQSVH------ 709
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S ++P + C+ C K F++ + L+ H R+HT +P+ C +C K F+Q S L+ H + HTG
Sbjct: 710 SGERPYI--CEVCGKGFSQRAYLQGHQRVHTRVKPYKCEMCGKGFSQSSRLEAHRRVHTG 767
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
+PYKC C GF++ S ++ H +
Sbjct: 768 GKPYKCEVCTKGFSESSRLQAHQR 791
Score = 116 bits (291), Expect = 2e-25
Identities = 61/170 (35%), Positives = 92/170 (54%), Gaps = 26/170 (15%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTH------ 1708
+ ++C EC + FS + L H + VH E+ + C C K F R++HL+ H + H
Sbjct: 573 KPYKCEECGKGFSRNSYLQGHQR-VHTGEKPYKCEECGKGFSRSSHLQGHQRVHTGEKPF 631
Query: 1709 ---QAGPSLS-------------SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHC 1752
+ G S +KP +KC+ C K F+K S L H R+HTGE+P+ C
Sbjct: 632 KCEECGKGFSWSFNLQIHQRVHTGEKP--YKCEECGKGFSKASTLLAHQRVHTGEKPYQC 689
Query: 1753 TLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
C K+F+Q+S LQ H H+GERPY C C GF+Q++ ++ H +R H+
Sbjct: 690 DECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGH-QRVHT 738
Score = 112 bits (281), Expect = 3e-24
Identities = 55/145 (37%), Positives = 86/145 (59%), Gaps = 10/145 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC + FS + L H + VH E+ + C C K F +A+ L H + H + +
Sbjct: 632 KCEECGKGFSWSFNLQIHQR-VHTGEKPYKCEECGKGFSKASTLLAHQRVH------TGE 684
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP ++CD C K+F++ S L+ H +H+GERP+ C +C K F+Q++ LQ H + HT +P
Sbjct: 685 KP--YQCDECGKSFSQRSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVHTRVKP 742
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHS 1802
YKC C GF+Q S ++ H +R H+
Sbjct: 743 YKCEMCGKGFSQSSRLEAH-RRVHT 766
Score = 108 bits (271), Expect = 4e-23
Identities = 55/156 (35%), Positives = 88/156 (56%), Gaps = 18/156 (11%)
Query: 1647 GNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQ 1706
G +P KE F+ ++ L H + VH ++ + C +C K F + L H +
Sbjct: 489 GEKPRKEH--------GNGFNWSSKLKDHQR-VHTGQKPYKCNICGKGFNHRSVLNVHQR 539
Query: 1707 THQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQ 1766
H + +KP +KC+ C+K F++ S L+ H R+HTGE+P+ C C K F++ S LQ
Sbjct: 540 VH------TGEKP--YKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEECGKGFSRNSYLQ 591
Query: 1767 VHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
H + HTGE+PYKC C GF++ S+++ H +R H+
Sbjct: 592 GHQRVHTGEKPYKCEECGKGFSRSSHLQGH-QRVHT 626
Score = 101 bits (252), Expect = 6e-21
Identities = 48/124 (38%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S L H R+H +P+KC QC + F+ S+L AH + HT
Sbjct: 763 RVHTGGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHRVHT 822
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASHF 589
G K +KC+ C K FS +L+ H R+HTG +P+ C C K FR S H++ H + F
Sbjct: 823 GEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHSSDKF 882
Query: 590 KHTE 593
+E
Sbjct: 883 YKSE 886
Score = 97.8 bits (242), Expect = 8e-20
Identities = 90/359 (25%), Positives = 131/359 (36%), Gaps = 53/359 (14%)
Query: 957 EDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKT 1016
+++ + Y C K F S + H + H KPY CG+G S +L H+
Sbjct: 242 QESIQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQ-- 299
Query: 1017 HTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTV 1076
++ N L + H KP KC E F HC + ++ +
Sbjct: 300 ---------NIEREDDIENSHLKSYQRVHTEEKPCKCGEYGENFN---HCSP-LNTYELI 346
Query: 1077 PSAVSATGETEGGDICMEEEEEHS-DRNASRK--SRPEVITFTEEETA--QLAKIRPQES 1131
TGE E+ HS D N+ + +R E + E E Q + ++ +
Sbjct: 347 H-----TGEMSYRHNIYEKAFSHSLDLNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQK 401
Query: 1132 ATVSEKVLVQSAAEKDRI-SELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHT 1190
EK+ K I S D Q + E N C F S +HT
Sbjct: 402 IHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNS-EECGNGFSLASHFQDLQIVHT 460
Query: 1191 GEKPYKCDEC--------------------------GKSFTVKSTLDCHVKTHTGQKLFS 1224
E+PYK C G F S L H + HTGQK +
Sbjct: 461 KEQPYKRYVCSNSFSHNLYLQGHPKIHIGEKPRKEHGNGFNWSSKLKDHQRVHTGQKPYK 520
Query: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C++C F+ + L VH R+HTG KP+KC C+ F S + H + H P K +
Sbjct: 521 CNICGKGFNHRSVLNVHQRVHTGEKPYKCEECDKGFSRSSYLQAHQRVHTGEKPYKCEE 579
Score = 90.9 bits (224), Expect = 1e-17
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 9/126 (7%)
Query: 1654 GRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPS 1713
G+ ++C C + FS ++ L H + VH R + C C K F + L+ H + H
Sbjct: 768 GKPYKCEVCTKGFSESSRLQAHQR-VHVEGRPYKCEQCGKGFSGYSSLQAHHRVH----- 821
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
+ +KP +KC+ C K F++ S L+ H R+HTGE+P+ C C K F S L +H + H+
Sbjct: 822 -TGEKP--YKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHS 878
Query: 1774 GERPYK 1779
++ YK
Sbjct: 879 SDKFYK 884
Score = 90.1 bits (222), Expect = 2e-17
Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 6/158 (3%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH-SGEDPTC 95
+KCE+C F + S+ + H R H KP++C+ C + F+ L H+ H G C
Sbjct: 743 YKCEMCGKGFSQSSRLEAHRRVHT-GGKPYKCEVCTKGFSESSRLQAHQRVHVEGRPYKC 801
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS +SL+AH +H E+ C CG F+ +S L H H G + + C
Sbjct: 802 EQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVH----TGEKPYKC 857
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRS 193
AC K F SS L H + H + + Y ++ S
Sbjct: 858 DACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSS 895
Score = 79.7 bits (195), Expect = 2e-14
Identities = 41/112 (36%), Positives = 58/112 (51%), Gaps = 9/112 (8%)
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
R + C C K F S L H R+HT EKP+KC C + F+ +S L AH + HTG K +K
Sbjct: 797 RPYKCEQCGKGFSGYSSLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYK 856
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKH 591
C C K F S L +H R+H+ DK +++ + K + +S H
Sbjct: 857 CDACGKGFRWSSGLLIHQRVHSS---------DKFYKSEDYGKDYPSSENLH 899
Score = 65.5 bits (158), Expect = 5e-10
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S L + EGR ++C +C + FS + L H + VH E+ + C VC K F + ++
Sbjct: 783 SSRLQAHQRVHVEGRPYKCEQCGKGFSGYSSLQAHHR-VHTGEKPYKCEVCGKGFSQRSN 841
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGER 1748
L+ H + H + +KP +KCD C K F S L H R+H+ ++
Sbjct: 842 LQAHQRVH------TGEKP--YKCDACGKGFRWSSGLLIHQRVHSSDK 881
Score = 57.0 bits (136), Expect = 2e-07
Identities = 28/80 (35%), Positives = 42/80 (52%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S+L H R+HT EKP+KC C + F S L H + H+
Sbjct: 819 RVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYKCDACGKGFRWSSGLLIHQRVHS 878
Query: 534 GIKAFKCQYCMKSFSTSGSL 553
K +K + K + +S +L
Sbjct: 879 SDKFYKSEDYGKDYPSSENL 898
Score = 55.1 bits (131), Expect = 6e-07
Identities = 41/172 (23%), Positives = 72/172 (41%), Gaps = 36/172 (20%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSS 1716
H+ E + F+ ++ L H K +H E+++ K+F +++L + H S +S
Sbjct: 381 HEYEENENVFNQSSCLQVHQK-IHTEEKLYTDIEYGKSFICSSNLDIQHRVHMEENSYNS 439
Query: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE- 1775
++ C F+ S + +HT E+P+ +C +F+ LQ H K H GE
Sbjct: 440 EE--------CGNGFSLASHFQDLQIVHTKEQPYKRYVCSNSFSHNLYLQGHPKIHIGEK 491
Query: 1776 -------------------------RPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+PYKC C GF +S + +H +R H+
Sbjct: 492 PRKEHGNGFNWSSKLKDHQRVHTGQKPYKCNICGKGFNHRSVLNVH-QRVHT 542
Score = 51.6 bits (122), Expect = 7e-06
Identities = 41/154 (26%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 1677 KEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQ 1736
+ VH E+ C + F + L + H S ++ + EKAF+
Sbjct: 316 QRVHTEEKPCKCGEYGENFNHCSPLNTYELIHTGEMS--------YRHNIYEKAFSHSLD 367
Query: 1737 LERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
L R+HT + P E FNQ S LQVH K HT E+ Y F SN+ +
Sbjct: 368 LNSIFRVHTRDEPHEYEENENVFNQSSCLQVHQKIHTEEKLYTDIEYGKSFICSSNLDI- 426
Query: 1797 MKRAHSYAGALQESAGHPEQDGEELSRTLHLEEV 1830
R H ++E++ + E+ G S H +++
Sbjct: 427 QHRVH-----MEENSYNSEECGNGFSLASHFQDL 455
Score = 47.8 bits (112), Expect = 1e-04
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 1722 FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCA 1781
+ C C + K S L + S I T E+P+ CT KAF+ S+ +VH + H +PY +
Sbjct: 225 YSCHDCGEDIMKVSLLNQES-IQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYS 283
Query: 1782 YCVMGFTQKSNMKLH 1796
C G S + +H
Sbjct: 284 SCGKGCNYSSLLHIH 298
Score = 46.2 bits (108), Expect = 3e-04
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 36/144 (25%)
Query: 1657 HQCLECDRAFSSAAVLMHHSK--EVHGRERIHGCPVCRKAFKRATHL-KEHMQTHQAGPS 1713
H C +CD S + L HH+ EVH +E + C C + + + L +E +QT +
Sbjct: 200 HFC-KCD----SVSWLSHHNDKLEVHRKEN-YSCHDCGEDIMKVSLLNQESIQTEE---- 249
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHM---- 1769
KP + C KAF+ S E H + H +P+ + C K N S L +H
Sbjct: 250 ----KP--YPCTGYRKAFSNDSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIER 303
Query: 1770 -------------KKHTGERPYKC 1780
+ HT E+P KC
Sbjct: 304 EDDIENSHLKSYQRVHTEEKPCKC 327
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/144 (25%), Positives = 52/144 (36%), Gaps = 18/144 (12%)
Query: 1147 DRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTV 1206
D +S L +L+ K C C + K S L+ I T EKPY C K+F+
Sbjct: 205 DSVSWLSHHNDKLEVHRKENYSCHDCGEDIMKVS-LLNQESIQTEEKPYPCTGYRKAFSN 263
Query: 1207 KSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVH-----------------MRLHTGAK 1249
S+ + H + H K ++ C + L +H R+HT K
Sbjct: 264 DSSSEVHQQFHLEGKPYTYSSCGKGCNYSSLLHIHQNIEREDDIENSHLKSYQRVHTEEK 323
Query: 1250 PFKCPHCELRFRTSGRRKTHMQFH 1273
P KC F T+ H
Sbjct: 324 PCKCGEYGENFNHCSPLNTYELIH 347
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 21/137 (15%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP---- 1712
+ C +C ++L S + E+ + C RKAF + + H Q H G
Sbjct: 225 YSCHDCGEDIMKVSLLNQES--IQTEEKPYPCTGYRKAFSNDSSSEVHQQFHLEGKPYTY 282
Query: 1713 ----------SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK 1762
SL + + D E S L+ + R+HT E+P C + FN
Sbjct: 283 SSCGKGCNYSSLLHIHQNIEREDDIEN-----SHLKSYQRVHTEEKPCKCGEYGENFNHC 337
Query: 1763 SALQVHMKKHTGERPYK 1779
S L + HTGE Y+
Sbjct: 338 SPLNTYELIHTGEMSYR 354
Score = 42.7 bits (99), Expect = 0.003
Identities = 21/50 (42%), Positives = 30/50 (60%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHE 1014
+ Y+CD C KGF+ SS L H R H+ +K YK + G+ + SS L +E
Sbjct: 853 KPYKCDACGKGFRWSSGLLIHQRVHSSDKFYKSEDYGKDYPSSENLHRNE 902
Score = 37.0 bits (84), Expect = 0.18
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CE+ +G S +L ++ + ++C C + FS + L H + VH E+ + C
Sbjct: 801 CEQCGKGFSGYS-SLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQR-VHTGEKPYKCD 858
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
C K F+ ++ L H + H + S+
Sbjct: 859 ACGKGFRWSSGLLIHQRVHSSDKFYKSE 886
Score = 33.9 bits (76), Expect = 1.5
Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 6/83 (7%)
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
KCD L+ H K + +SCH C K SL + T KP+ C
Sbjct: 203 KCDSVSWLSHHNDKLEVHRKEN-----YSCHDCGEDIM-KVSLLNQESIQTEEKPYPCTG 256
Query: 1256 CELRFRTSGRRKTHMQFHYKPDP 1278
F + H QFH + P
Sbjct: 257 YRKAFSNDSSSEVHQQFHLEGKP 279
>gi|153792259 zinc finger protein 778 [Homo sapiens]
Length = 729
Score = 219 bits (557), Expect = 3e-56
Identities = 173/665 (26%), Positives = 264/665 (39%), Gaps = 130/665 (19%)
Query: 70 QCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDE 129
QC + F+ N+ + C + F + L+A H EE CG
Sbjct: 174 QCGKAFSSTPNVVSQQACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKA 233
Query: 130 FTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIR---------- 179
T A +E H A H C+ C K F ++ L ++ H +
Sbjct: 234 LTHSMGCATPVEMH----AVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKA 289
Query: 180 --VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK 237
VSS+ + + I + C CGK F S L++H++ G++P++C +CGKA
Sbjct: 290 SPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKACGGF 349
Query: 238 GALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSL 297
L H HT EKP AC C F L +HV R+H+ +K Y C+ C F
Sbjct: 350 YLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHV-RIHTGIK---PYTCSYCGKAFTVR 405
Query: 298 GSLNTHISKMHMG---------GPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQ 348
L H+ + H G G TSS T HV T T + + T +SS
Sbjct: 406 CGLTRHV-RTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSS- 463
Query: 349 PSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAA 408
L+E A + +G+ P +Q + SGL+
Sbjct: 464 ---------------LTEHARIHTGEKPYECKQCG----------KAFTGRSGLTK---- 494
Query: 409 AHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPF 468
H +T + P + + + + L + K ++ PF
Sbjct: 495 -------HMRT--------------HTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPF 533
Query: 469 LPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAH 528
+ C C K FR S L +HI+IHT KP++C C + F V S+LT H
Sbjct: 534 I--------------CTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEH 579
Query: 529 IKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588
I+THTG K ++C+ C K+F+TS L VHIR HTG +P+ C C K F +S H H +H
Sbjct: 580 IRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTH 639
Query: 589 FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNN 648
++P + + G + +
Sbjct: 640 TG------------------------------EKPYICNECG-----KAFRASSHLHKHG 664
Query: 649 FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHT 708
++ +PYKC C +AY + LK+H++++T E+ F C CG+ F ++ L H + HT
Sbjct: 665 RIHTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHHTQIHT 724
Query: 709 GLKSF 713
K F
Sbjct: 725 DEKPF 729
Score = 211 bits (537), Expect = 5e-54
Identities = 164/646 (25%), Positives = 249/646 (38%), Gaps = 93/646 (14%)
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K FS ++ + ++ +L S CG+ F QS L H G K
Sbjct: 175 CGKAFSSTPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHN----GEETWKWKP 229
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K S ++ H RN + C CGK F+ + LT ++
Sbjct: 230 CGKALTHSMGCATPVEMHAV----------RN------PHVCRECGKAFRYTAYLTGRVQ 273
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHS 277
+H GE+P + ECGKA +L H+ H EKP C C AF+ L HVQ
Sbjct: 274 VHPGEKPCELEECGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPG 333
Query: 278 EVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQ 337
+ Y C +C LN H K H T A V+ F+
Sbjct: 334 Q----KPYECKDCGKACGGFYLLNEH-GKTH-------TREKPFACVVCGKYFRNSSCLN 381
Query: 338 TEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQAL 397
+ + + L+ +G+ P + D +
Sbjct: 382 NHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCK----------DCGKAFC 431
Query: 398 ENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKK 457
+SGL+ + T + D + T+ + E P + +
Sbjct: 432 TSSGLT---------EHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQC 482
Query: 458 EKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFR 517
K + L +R G + + C C K + + L H++ HT EKPF C C +
Sbjct: 483 GKAFTGRSG--LTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRK 540
Query: 518 AFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577
+F S L HI+ HTGIK ++C+ C K+F+ S SL HIR HTG +P+ C C K F T
Sbjct: 541 SFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTT 600
Query: 578 SGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
S H HI +H ++P + + G
Sbjct: 601 SSHLIVHIRTHTG------------------------------EKPYICKECG------- 623
Query: 638 NQFFQS--YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFV 695
F S + + ++PY C C +A++ S HL +H R HTG+KP+KC +CG+ +
Sbjct: 624 KAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYN 683
Query: 696 SAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPY 741
+LK H++T+T + F C C +F L H IH D +P+
Sbjct: 684 RFYLLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHHTQIHTDEKPF 729
Score = 201 bits (511), Expect = 5e-51
Identities = 117/319 (36%), Positives = 148/319 (46%), Gaps = 32/319 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C YC K F L +HVR+HTGEKPY CK CG+ F +S L H +THTG K +
Sbjct: 391 KPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYE 450
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C SFT + SLT H H KPY+C C + F KHM+ H TG
Sbjct: 451 CKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTH---------TG 501
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E E ++ N V T TEE+ TV K
Sbjct: 502 EKP-----YECKDCGKAYNRVYLLNEHVKTHTEEKPF---------ICTVCRKSF----- 542
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
R S +K ++ K C C K+F S L H+R HTGEKPY+C CGK+F
Sbjct: 543 ---RNSSCLNKHIQIHTGIKPYECKD-CGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAF 598
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
T S L H++THTG+K + C C AF++ L H R HTG KP+ C C FR S
Sbjct: 599 TTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASS 658
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H + H P K ++
Sbjct: 659 HLHKHGRIHTGQKPYKCKE 677
Score = 201 bits (510), Expect = 7e-51
Identities = 108/304 (35%), Positives = 153/304 (50%), Gaps = 15/304 (4%)
Query: 464 KKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKS 523
+ S L +R G++ + C YC K F L RH+R HT EKP+ C C +AF S
Sbjct: 375 RNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSS 434
Query: 524 TLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKT 583
LT H++THTG K ++C+ C KSF+ S SL H R+HTG +P+ C C K F
Sbjct: 435 GLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTK 494
Query: 584 HIASHF--KHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFF 641
H+ +H K E + A RV N V ++P + T + + F
Sbjct: 495 HMRTHTGEKPYECKDC----GKAYNRVYLLNEHVKTHTEEKPFICT-------VCRKSFR 543
Query: 642 QSYFNNNF--VNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGV 699
S N ++ +PY+C C + + S L +HIR+HTGEKP++C CG+ F ++
Sbjct: 544 NSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSH 603
Query: 700 LKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKH 759
L HIRTHTG K + C C AF + L H H +PY+C C K F+ S + KH
Sbjct: 604 LIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKH 663
Query: 760 MKTH 763
+ H
Sbjct: 664 GRIH 667
Score = 197 bits (502), Expect = 6e-50
Identities = 112/336 (33%), Positives = 159/336 (47%), Gaps = 40/336 (11%)
Query: 961 DQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGV 1020
D ++ Y C C K L +H ++HT EKP+ C +CG+ F +S L +H + HTG+
Sbjct: 331 DPGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGI 390
Query: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
K ++CS C +FT LTRH+ TH KPY C C + F T+ +H++ H
Sbjct: 391 KPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTH------- 443
Query: 1081 SATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV 1140
TGE + E D S + T + +P E +
Sbjct: 444 --TGE---------KPYECKDCGKSFTVSSSLTEHARIHTGE----KPYECKQCGKAFTG 488
Query: 1141 QSAAEKDRISELRDKQAELQDEPKHAN------------------CCTYCPKSFKKPSDL 1182
+S K + +K E +D K N CT C KSF+ S L
Sbjct: 489 RSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCL 548
Query: 1183 VRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHM 1242
+H++IHTG KPY+C +CGK+FTV S+L H++THTG+K + C VC AF+T L VH+
Sbjct: 549 NKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHI 608
Query: 1243 RLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP 1278
R HTG KP+ C C F +S H + H P
Sbjct: 609 RTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKP 644
Score = 182 bits (463), Expect = 2e-45
Identities = 105/320 (32%), Positives = 144/320 (45%), Gaps = 16/320 (5%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y C C K F SS L +HVR+HTGEKPY+CK CG+ F S L H + HTG K +
Sbjct: 419 KPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYE 478
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH-QTVPSAVSAT 1083
C C +FT LT+HM TH KPY+C C + + +H+K H + P +
Sbjct: 479 CKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVC 538
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFT-----EEETAQLAKIRPQESATVSEKV 1138
++ C+ + + + + TFT E +P E +
Sbjct: 539 RKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAF 598
Query: 1139 LVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCD 1198
S I +R E C C K+F S L+ H R HTGEKPY C+
Sbjct: 599 TTSSHL----IVHIRTHTGE------KPYICKECGKAFASSSHLIEHRRTHTGEKPYICN 648
Query: 1199 ECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL 1258
ECGK+F S L H + HTGQK + C C A++ LK H++ +T + F C C
Sbjct: 649 ECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGK 708
Query: 1259 RFRTSGRRKTHMQFHYKPDP 1278
F+ S H Q H P
Sbjct: 709 SFKNSSCLNHHTQIHTDEKP 728
Score = 182 bits (462), Expect = 3e-45
Identities = 160/631 (25%), Positives = 250/631 (39%), Gaps = 48/631 (7%)
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRN--------IDRSGFTYSC-PHCGKTFQK 208
C + F S L H++T + Y R+ + + G +S CGK F
Sbjct: 122 CGEAFSEHSGLSTHVRTQNTGDSCVSNHYERDFFIPCQKTLFKIGEQFSVLGQCGKAFSS 181
Query: 209 PSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNL 268
+ + T +R S CG+ F + LQ H GE+ C A +
Sbjct: 182 TPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSMGC 240
Query: 269 QSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTAT 328
+ V+ +H+ V+N + C EC F+ L + ++H G A ++++
Sbjct: 241 ATPVE-MHA-VRN--PHVCRECGKAFRYTAYLTGRV-QVHPGEKPCELEECGKASPVSSS 295
Query: 329 LFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVG- 387
L Q + + E + +S LS+ + GQ P + G
Sbjct: 296 LTQHVRIHAAEKPCECKECGKAFTGLSG-------LSKHVQTDPGQKPYECKDCGKACGG 348
Query: 388 ---INQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ-NPDVSSVSNEQ-TDPTDA 442
+N+ E + N SC H P S + T
Sbjct: 349 FYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGL 408
Query: 443 EQEKEQESPEK-LDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
+ + EK K+ S L +R G + + C C K F S L H
Sbjct: 409 TRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHA 468
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
RIHT EKP++C QC +AF +S LT H++THTG K ++C+ C K+++ L H++ HT
Sbjct: 469 RIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHT 528
Query: 562 GVRPFACPHCDKKFRTSGHRKTHIASH--FKHTELRKMRHQRKPAKVRVGKTNIPVPDIP 619
+PF C C K FR S HI H K E + + + P
Sbjct: 529 EEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKP 588
Query: 620 LQEPI----LITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQH 675
+ + T LI I + ++PY C C +A+ S HL +H
Sbjct: 589 YECKVCGKAFTTSSHLIVHIR-------------THTGEKPYICKECGKAFASSSHLIEH 635
Query: 676 IRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
R+HTGEKP+ C++CG+ F ++ L H R HTG K +KC C A+ L+ H+ +
Sbjct: 636 RRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFYLLKEHLKTY 695
Query: 736 NDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+ + ++C C K+FK S H + H E
Sbjct: 696 TEEQVFVCKDCGKSFKNSSCLNHHTQIHTDE 726
Score = 178 bits (452), Expect = 4e-44
Identities = 104/287 (36%), Positives = 138/287 (48%), Gaps = 23/287 (8%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+ C C +F RH+R H +KP+ C C + F LT H TH+GE P C
Sbjct: 393 YTCSYCGKAFTVRCGLTRHVRTHT-GEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYEC 451
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+ +SL H +H E+ C +CG FT +S L HM H G + + C
Sbjct: 452 KDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTH----TGEKPYEC 507
Query: 156 KACKKEFETSSELKEHMKTHYK------------IRVSSTRSYNRNIDRSGFTYSCPHCG 203
K C K + L EH+KTH + R SS + + I Y C CG
Sbjct: 508 KDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCG 567
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
KTF S LT HIR HTGE+P++C CGKAF L H+ HTGEKP+ C C AF+
Sbjct: 568 KTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFA 627
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
+L H +R H+ K Y C EC F++ L+ H ++H G
Sbjct: 628 SSSHLIEH-RRTHTGEK---PYICNECGKAFRASSHLHKH-GRIHTG 669
Score = 171 bits (434), Expect = 5e-42
Identities = 104/301 (34%), Positives = 147/301 (48%), Gaps = 36/301 (11%)
Query: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCP 96
+C+ C +F S +H++ + KP+ C C + + L H TH+ E P C
Sbjct: 310 ECKECGKAFTGLSGLSKHVQT-DPGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACV 368
Query: 97 VCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK 156
VC K F + L H+ +H + CS CG FT++ L H+ H G + + CK
Sbjct: 369 VCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTH----TGEKPYTCK 424
Query: 157 ACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHI 216
C K F TSS L EH++TH + Y C CGK+F S LT H
Sbjct: 425 DCGKAFCTSSGLTEHVRTHTGEK----------------PYECKDCGKSFTVSSSLTEHA 468
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
RIHTGE+P++C +CGKAF + L HM HTGEKP+ C C A+++ L HV + H
Sbjct: 469 RIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHV-KTH 527
Query: 277 SEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG---------GPQNSTSSTETAHVLTA 327
+E K + CT C F++ LN HI ++H G G + SS+ T H+ T
Sbjct: 528 TEEK---PFICTVCRKSFRNSSCLNKHI-QIHTGIKPYECKDCGKTFTVSSSLTEHIRTH 583
Query: 328 T 328
T
Sbjct: 584 T 584
Score = 168 bits (426), Expect = 4e-41
Identities = 97/285 (34%), Positives = 133/285 (46%), Gaps = 32/285 (11%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
++C+ C SF S H R H +KP+ C QC + F LT H TH+GE P C
Sbjct: 449 YECKDCGKSFTVSSSLTEHARIHT-GEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYEC 507
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K ++RV L H+ H +E+ IC+ C F S L H++ H G + + C
Sbjct: 508 KDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHIQIH----TGIKPYEC 563
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFT-----------------YS 198
K C K F SS L EH++TH + + Y + FT Y
Sbjct: 564 KDCGKTFTVSSSLTEHIRTH-----TGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYI 618
Query: 199 CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFC 258
C CGK F S L H R HTGE+P+ C+ECGKAF L H HTG+KP+ C C
Sbjct: 619 CKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKEC 678
Query: 259 PAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
A+++ L+ H++ E + C +C FK+ LN H
Sbjct: 679 GKAYNRFYLLKEHLKTYTEE----QVFVCKDCGKSFKNSSCLNHH 719
Score = 159 bits (402), Expect = 2e-38
Identities = 89/257 (34%), Positives = 127/257 (49%), Gaps = 19/257 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
++C+ C +F S +HMR H +KP+ C C + +N + L H TH+ E P C
Sbjct: 477 YECKQCGKAFTGRSGLTKHMRTHT-GEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFIC 535
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
VC K F + L HI +H + C +CG FT+ S L H+ H G + + C
Sbjct: 536 TVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTH----TGEKPYEC 591
Query: 156 KACKKEFETSSELKEHMKTHY-----------KIRVSSTRSYNRNIDRSGFT-YSCPHCG 203
K C K F TSS L H++TH K SS+ +G Y C CG
Sbjct: 592 KVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECG 651
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S L +H RIHTG++P+KC ECGKA+N+ L+ H+ +T E+ C C +F
Sbjct: 652 KAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGKSFK 711
Query: 264 QKGNLQSHVQRVHSEVK 280
L H Q +H++ K
Sbjct: 712 NSSCLNHHTQ-IHTDEK 727
Score = 157 bits (396), Expect = 1e-37
Identities = 105/323 (32%), Positives = 138/323 (42%), Gaps = 37/323 (11%)
Query: 972 CNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNAS 1031
C K SS L QHVR H EKP +CK CG+ F L H +T G K + C C +
Sbjct: 286 CGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKA 345
Query: 1032 FTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTV-PSAVSATGETEGGD 1090
L H TH KP+ C C + FR + H++ H + P S G+
Sbjct: 346 CGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVR 405
Query: 1091 ICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRIS 1150
+ V T T E +P + S + +
Sbjct: 406 CGLTRH---------------VRTHTGE--------KPYTCKDCGKAFCTSSGLTEHVRT 442
Query: 1151 ELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTL 1210
+K E +D C KSF S L H RIHTGEKPY+C +CGK+FT +S L
Sbjct: 443 HTGEKPYECKD----------CGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGL 492
Query: 1211 DCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHM 1270
H++THTG+K + C C A++ L H++ HT KPF C C FR S H+
Sbjct: 493 TKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHI 552
Query: 1271 QFH--YKP-DPKKARKPMTRSSS 1290
Q H KP + K K T SSS
Sbjct: 553 QIHTGIKPYECKDCGKTFTVSSS 575
Score = 144 bits (363), Expect = 8e-34
Identities = 97/349 (27%), Positives = 143/349 (40%), Gaps = 29/349 (8%)
Query: 946 LDLQAQGSQFLEDNEDQSR-------RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCK 998
LD + G FL + Q+R +++ C K S V H P+ C+
Sbjct: 197 LDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSMGCATPVEMHAVRNPHVCR 256
Query: 999 LCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEE 1058
CG+ F + L + H G K C + + SLT+H+ H + KP +C C +
Sbjct: 257 ECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVSSSLTQHVRIHAAEKPCECKECGK 316
Query: 1059 GFRTTVHCKKHMKRHQ-TVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVI---- 1113
F KH++ P G+ GG + EH + K V+
Sbjct: 317 AFTGLSGLSKHVQTDPGQKPYECKDCGKACGGFYLL---NEHGKTHTREKPFACVVCGKY 373
Query: 1114 ----TFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCC 1169
+ I+P + + V R R + ++P C
Sbjct: 374 FRNSSCLNNHVRIHTGIKPYTCSYCGKAFTV-------RCGLTRHVRTHTGEKP---YTC 423
Query: 1170 TYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCS 1229
C K+F S L HVR HTGEKPY+C +CGKSFTV S+L H + HTG+K + C C
Sbjct: 424 KDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCG 483
Query: 1230 NAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP 1278
AF+ + L HMR HTG KP++C C + H++ H + P
Sbjct: 484 KAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKP 532
Score = 137 bits (344), Expect = 1e-31
Identities = 75/215 (34%), Positives = 101/215 (46%), Gaps = 22/215 (10%)
Query: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPV 97
C +C SF S +H++ H KP+ C C +TF V +LT H TH+GE P C V
Sbjct: 535 CTVCRKSFRNSSCLNKHIQIHT-GIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKV 593
Query: 98 CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKA 157
C K F+ + L HI H E+ IC ECG F S H+ EHR+ G + + C
Sbjct: 594 CGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSS----HLIEHRRTHTGEKPYICNE 649
Query: 158 CKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIR 217
C K F SS L +H + H + Y C CGK + + L H++
Sbjct: 650 CGKAFRASSHLHKHGRIHTGQK----------------PYKCKECGKAYNRFYLLKEHLK 693
Query: 218 IHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKP 252
+T E+ F C +CGK+F L H HT EKP
Sbjct: 694 TYTEEQVFVCKDCGKSFKNSSCLNHHTQIHTDEKP 728
Score = 127 bits (319), Expect = 1e-28
Identities = 97/375 (25%), Positives = 145/375 (38%), Gaps = 52/375 (13%)
Query: 972 CNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNAS 1031
C K F + ++ ++ T ++ CG F++ L++ +H G + + C +
Sbjct: 175 CGKAFSSTPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKA 233
Query: 1032 FTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDI 1091
T + + H P+ C C + FR T + ++ H G
Sbjct: 234 LTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHP-------------GEKP 280
Query: 1092 CMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISE 1151
C EE K+ P + T+ A+ +P E + S K ++
Sbjct: 281 CELEE--------CGKASPVSSSLTQHVRIHAAE-KPCECKECGKAFTGLSGLSKHVQTD 331
Query: 1152 LRDKQAELQDEPKHAN------------------CCTYCPKSFKKPSDLVRHVRIHTGEK 1193
K E +D K C C K F+ S L HVRIHTG K
Sbjct: 332 PGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIK 391
Query: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKC 1253
PY C CGK+FTV+ L HV+THTG+K ++C C AF T L H+R HTG KP++C
Sbjct: 392 PYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYEC 451
Query: 1254 PHCELRFRTSGRRKTHMQFHYKPDP---KKARKPMTRSSS--------EGLQPVNLLNSS 1302
C F S H + H P K+ K T S G +P +
Sbjct: 452 KDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCG 511
Query: 1303 STDPNVFIMNNSVLT 1317
V+++N V T
Sbjct: 512 KAYNRVYLLNEHVKT 526
Score = 116 bits (291), Expect = 2e-25
Identities = 78/311 (25%), Positives = 129/311 (41%), Gaps = 12/311 (3%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G ++ V C K F ++V + T ++ C F +S L A +H G +
Sbjct: 166 GEQFSVLGQCGKAFSSTPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEET 224
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH--FKHTELR 595
+K + C K+ + S + +H P C C K FR + + + H K EL
Sbjct: 225 WKWKPCGKALTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELE 284
Query: 596 KMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADR 655
+ + I + P + + + K+ + +
Sbjct: 285 ECGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQ---------TDPGQK 335
Query: 656 PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715
PY+C C +A L +H ++HT EKPF C CG+ F ++ L H+R HTG+K + C
Sbjct: 336 PYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTC 395
Query: 716 LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQ 775
C AFT L RH+ H +PY C C K F TS +H++TH E + +
Sbjct: 396 SYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCG 455
Query: 776 QAASIDDSTVD 786
++ ++ S +
Sbjct: 456 KSFTVSSSLTE 466
Score = 110 bits (276), Expect = 1e-23
Identities = 60/173 (34%), Positives = 91/173 (52%), Gaps = 11/173 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
C++ G SG L + + ++C +C +A++ +L H K H E+ C
Sbjct: 479 CKQCGKAFTGRSG-LTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVK-THTEEKPFICT 536
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
VCRK+F+ ++ L +H+Q H + KP ++C C K F S L H R HTGE+P
Sbjct: 537 VCRKSFRNSSCLNKHIQIH------TGIKP--YECKDCGKTFTVSSSLTEHIRTHTGEKP 588
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+ C +C KAF S L VH++ HTGE+PY C C F S++ H +R H+
Sbjct: 589 YECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEH-RRTHT 640
Score = 109 bits (272), Expect = 3e-23
Identities = 55/159 (34%), Positives = 87/159 (54%), Gaps = 9/159 (5%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
VS +L + + ++C +C +AF+ + L H + H E+ + C C KA+ R
Sbjct: 460 VSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMR-THTGEKPYECKDCGKAYNRVY 518
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
L EH++TH + +KP F C C K+F S L +H +IHTG +P+ C C K F
Sbjct: 519 LLNEHVKTH------TEEKP--FICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTF 570
Query: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
S+L H++ HTGE+PY+C C FT S++ +H++
Sbjct: 571 TVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIR 609
Score = 108 bits (270), Expect = 5e-23
Identities = 54/144 (37%), Positives = 81/144 (56%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C + F+ ++ L H + H E+ + C VC KAF ++HL H++TH
Sbjct: 559 KPYECKDCGKTFTVSSSLTEHIR-THTGEKPYECKVCGKAFTTSSHLIVHIRTH------ 611
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP + C C KAFA S L H R HTGE+P+ C C KAF S L H + HTG
Sbjct: 612 TGEKPYI--CKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTG 669
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
++PYKC C + + +K H+K
Sbjct: 670 QKPYKCKECGKAYNRFYLLKEHLK 693
Score = 106 bits (264), Expect = 2e-22
Identities = 53/144 (36%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ + C C +AF+ L H + H E+ + C C KAF ++ L EH++TH
Sbjct: 391 KPYTCSYCGKAFTVRCGLTRHVR-THTGEKPYTCKDCGKAFCTSSGLTEHVRTH------ 443
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C K+F S L H+RIHTGE+P+ C C KAF +S L HM+ HTG
Sbjct: 444 TGEKP--YECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTG 501
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY+C C + + + H+K
Sbjct: 502 EKPYECKDCGKAYNRVYLLNEHVK 525
Score = 100 bits (248), Expect = 2e-20
Identities = 53/157 (33%), Positives = 86/157 (54%), Gaps = 9/157 (5%)
Query: 1640 VSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRAT 1699
VS +L + + ++C C +AF++++ L+ H + H E+ + C C KAF ++
Sbjct: 572 VSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIR-THTGEKPYICKECGKAFASSS 630
Query: 1700 HLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAF 1759
HL EH +TH + +KP + C+ C KAF S L +H RIHTG++P+ C C KA+
Sbjct: 631 HLIEHRRTH------TGEKPYI--CNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAY 682
Query: 1760 NQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
N+ L+ H+K +T E+ + C C F S + H
Sbjct: 683 NRFYLLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHH 719
Score = 92.0 bits (227), Expect = 5e-18
Identities = 51/141 (36%), Positives = 72/141 (51%), Gaps = 9/141 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C EC +AF+ + L H + G ++ + C C KA L EH +TH + +
Sbjct: 310 ECKECGKAFTGLSGLSKHVQTDPG-QKPYECKDCGKACGGFYLLNEHGKTH------TRE 362
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP F C C K F S L H RIHTG +P+ C+ C KAF + L H++ HTGE+P
Sbjct: 363 KP--FACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKP 420
Query: 1778 YKCAYCVMGFTQKSNMKLHMK 1798
Y C C F S + H++
Sbjct: 421 YTCKDCGKAFCTSSGLTEHVR 441
Score = 90.9 bits (224), Expect = 1e-17
Identities = 72/304 (23%), Positives = 119/304 (39%), Gaps = 57/304 (18%)
Query: 514 QCFRAFAVKSTLTAHIKT-HTGIKAFKCQY------------------------CMKSFS 548
QC AF+ S L+ H++T +TG Y C K+FS
Sbjct: 121 QCGEAFSEHSGLSTHVRTQNTGDSCVSNHYERDFFIPCQKTLFKIGEQFSVLGQCGKAFS 180
Query: 549 TSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR------------- 595
++ ++ V + T R C + F + + SH +
Sbjct: 181 STPNV-VSQQACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSMG 239
Query: 596 -----KMRHQRKPAKVR-VGKT-------NIPVPDIPLQEPILITDLGLIQPIPKNQFFQ 642
+M R P R GK V P ++P + + G P+
Sbjct: 240 CATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVS-----S 294
Query: 643 SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKA 702
S + ++ A++P +C C +A+ L +H+++ G+KP++C CG+ +L
Sbjct: 295 SLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKACGGFYLLNE 354
Query: 703 HIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT 762
H +THT K F C++C F L H+ IH ++PY C YC K F +H++T
Sbjct: 355 HGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRT 414
Query: 763 HRYE 766
H E
Sbjct: 415 HTGE 418
Score = 87.8 bits (216), Expect = 9e-17
Identities = 41/103 (39%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 950 AQGSQFLEDNEDQS-RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSG 1008
A S +E + + Y C+ C K F+ SSHL +H R HTG+KPYKCK CG+ +
Sbjct: 627 ASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFY 686
Query: 1009 VLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPY 1051
+LK H KT+T + F C C SF + L H H KP+
Sbjct: 687 LLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHHTQIHTDEKPF 729
Score = 86.3 bits (212), Expect = 3e-16
Identities = 52/169 (30%), Positives = 74/169 (43%), Gaps = 35/169 (20%)
Query: 1657 HQCLECDRAFSSAAVL-----MHHSKE----------------------VHGRERIHGCP 1689
H C EC +AF A L +H ++ +H E+ C
Sbjct: 253 HVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVSSSLTQHVRIHAAEKPCECK 312
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF + L +H+QT QKP ++C C KA L H + HT E+P
Sbjct: 313 ECGKAFTGLSGLSKHVQTD------PGQKP--YECKDCGKACGGFYLLNEHGKTHTREKP 364
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
F C +C K F S L H++ HTG +PY C+YC FT + + H++
Sbjct: 365 FACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVR 413
Score = 68.9 bits (167), Expect = 4e-11
Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 1678 EVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQL 1737
E+H H C C KAF+ +L +Q H +KP + + C KA S L
Sbjct: 245 EMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPG------EKP--CELEECGKASPVSSSL 296
Query: 1738 ERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYC 1783
+H RIH E+P C C KAF S L H++ G++PY+C C
Sbjct: 297 TQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDC 342
Score = 55.1 bits (131), Expect = 6e-07
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 26/160 (16%)
Query: 1661 ECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQA---------G 1711
+C +AFSS ++ S++ R+R C + F ++L+ +H G
Sbjct: 174 QCGKAFSSTPNVV--SQQACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCG 231
Query: 1712 PSLSS-------------QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
+L+ + P V C C KAF + L ++H GE+P C KA
Sbjct: 232 KALTHSMGCATPVEMHAVRNPHV--CRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKA 289
Query: 1759 FNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
S+L H++ H E+P +C C FT S + H++
Sbjct: 290 SPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQ 329
Score = 43.9 bits (102), Expect = 0.001
Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Query: 662 CHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGA 721
C +A+ + ++ ++ T ++ S CG F++ L+A +H G +++K C A
Sbjct: 175 CGKAFSSTPNVVSQ-QACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKA 233
Query: 722 FTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASID 781
T + +H P++C C K F+ + ++ H E +L++ +A+ +
Sbjct: 234 LTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVS 293
Query: 782 DSTVDQQSMQAS 793
S + A+
Sbjct: 294 SSLTQHVRIHAA 305
>gi|116256455 zinc finger protein 429 [Homo sapiens]
Length = 674
Score = 218 bits (555), Expect = 4e-56
Identities = 154/535 (28%), Positives = 227/535 (42%), Gaps = 76/535 (14%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLI 122
K + CD + F N +K H+G+ P C C K F ++ L H +H +E
Sbjct: 143 KMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYR 202
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182
C E G+ F S L H++ G + + C+ C K F S L H + H +
Sbjct: 203 CKEFGNAFNQSSALT----NHKRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEK--- 255
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
Y C CGK F + S LT H RIH+GE+P+KC ECGK F+
Sbjct: 256 -------------PYKCKECGKAFSRYSTLTTHKRIHSGEKPYKCDECGKTFSISSTFTK 302
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
H I HT EKP+ C C AF++ L SH +R+H+ K Y C EC F +L
Sbjct: 303 HKIIHTEEKPYKCKECGKAFNRSSTLTSH-KRIHTGEK---PYKCEECGKAFNWSSTLTK 358
Query: 303 HISKMHMG---------GPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQA 353
H +H G G + SS T H T + ++ T +S+
Sbjct: 359 H-KVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSST------ 411
Query: 354 VSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPND 413
L++ + +G+ P N + + S + H +
Sbjct: 412 ----------LTQDKKIHTGEKPY-----------NCEECGKVFTYSSTLTRHKRIHTEE 450
Query: 414 SCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSI 473
P+ N + N + T + E P K ++ K K+S L
Sbjct: 451 K-------PYKCN-ECGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAF--KQSSNLNSHK 500
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
+ +G + + C C K F S L +H +IHT EKP+KC +C +AF S LT H K HT
Sbjct: 501 KIHSGEKPYKCEECGKAFILSSRLTQHKKIHTGEKPYKCEECGKAFNRSSRLTQHKKIHT 560
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKF----RTSGHRKTH 584
G K +KC+ C K+F+ S +L H ++H+G +P+ C C K F R + H+K H
Sbjct: 561 GEKPYKCKQCDKAFTHSSNLSSHKKIHSGEKPYKCEECGKAFNRSSRLTQHKKIH 615
Score = 211 bits (538), Expect = 4e-54
Identities = 153/534 (28%), Positives = 229/534 (42%), Gaps = 58/534 (10%)
Query: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCP 96
+C+ C SF SQ +H + H R + +RC + FN LT HK + GE C
Sbjct: 174 QCKKCGKSFCMLSQLTQHKKIHIR-ENTYRCKEFGNAFNQSSALTNHKRIYVGEKHYRCE 232
Query: 97 VCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACK 156
C K F+ ++L H +H E+ C ECG F+ S L H H +G + + C
Sbjct: 233 ECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIH----SGEKPYKCD 288
Query: 157 ACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHI 216
C K F SS +H H + + Y C CGK F + S LT H
Sbjct: 289 ECGKTFSISSTFTKHKIIHTEEK----------------PYKCKECGKAFNRSSTLTSHK 332
Query: 217 RIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVH 276
RIHTGE+P+KC ECGKAFN L H + HTGEKP+ C C AF+Q L H +++H
Sbjct: 333 RIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFNQSSRLTRH-KKIH 391
Query: 277 SEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQ 336
+ Y +C VF +L T K+H G + ++TL
Sbjct: 392 T---GEEPYKFEKCGRVFTCSSTL-TQDKKIHTGEKPYNCEECGKVFTYSSTL------- 440
Query: 337 QTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQ 395
T + +P + L+ + +G+ P ++ +
Sbjct: 441 -TRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTGEKPYKCEECG----------KA 489
Query: 396 ALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLD 455
++S L+S + H+ + + + + + T ++ E P K +
Sbjct: 490 FKQSSNLNS-------HKKIHSGEKPYKCEECGKAFILSSRL--TQHKKIHTGEKPYKCE 540
Query: 456 KKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQC 515
+ K +S L + G + + C C K F S+L H +IH+ EKP+KC +C
Sbjct: 541 ECGKAF--NRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHSGEKPYKCEEC 598
Query: 516 FRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLH-TGVRPFAC 568
+AF S LT H K HT K +KC+ C K+F+ S L H ++H GV AC
Sbjct: 599 GKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIHRMGVVAHAC 652
Score = 199 bits (507), Expect = 2e-50
Identities = 123/340 (36%), Positives = 166/340 (48%), Gaps = 32/340 (9%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C +F + S H R H +KP++CD+C +TF++ T HK H+ E P C
Sbjct: 257 YKCKECGKAFSRYSTLTTHKRIHS-GEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKC 315
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+R ++L +H +H E+ C ECG F S L H H G + + C
Sbjct: 316 KECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIH----TGEKPYKC 371
Query: 156 KACKKEFETSSELKEHMKTH-----YKIR-------VSSTRSYNRNIDRSGFTYSCPHCG 203
+ C K F SS L H K H YK SST + ++ I Y+C CG
Sbjct: 372 EECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYNCEECG 431
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F S LTRH RIHT E+P+KC+ECGKAFN+ L +H HTGEKP+ C C AF
Sbjct: 432 KVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAFK 491
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG---------GPQN 314
Q NL SH +++HS K Y C EC F L S T K+H G G
Sbjct: 492 QSSNLNSH-KKIHSGEK---PYKCEECGKAF-ILSSRLTQHKKIHTGEKPYKCEECGKAF 546
Query: 315 STSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAV 354
+ SS T H T + +Q + T +S+ S + +
Sbjct: 547 NRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKI 586
Score = 193 bits (490), Expect = 1e-48
Identities = 143/553 (25%), Positives = 224/553 (40%), Gaps = 56/553 (10%)
Query: 220 TGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEV 279
T + + C K F + +HTG+KP C C +F L H +++H
Sbjct: 140 TQSKMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQH-KKIHIRE 198
Query: 280 KNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTE 339
TY C E F +L H ++++G A +TL T
Sbjct: 199 N---TYRCKEFGNAFNQSSALTNH-KRIYVGEKHYRCEECGKAFNHYSTL--------TN 246
Query: 340 AQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALE 398
+ +P + + L+ + SG+ P + T I+ + +
Sbjct: 247 HKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIHSGEKPYKCDECGKTFSISSTFTKHKII 306
Query: 399 NSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKE 458
+ T + + N + T ++ E P K ++
Sbjct: 307 H-------------------TEEKPYKCKECGKAFNRSSTLTSHKRIHTGEKPYKCEECG 347
Query: 459 KKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRA 518
K S L G + + C C K F + S L RH +IHT E+P+K +C R
Sbjct: 348 KAF--NWSSTLTKHKVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRV 405
Query: 519 FAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTS 578
F STLT K HTG K + C+ C K F+ S +L H R+HT +P+ C C K F
Sbjct: 406 FTCSSTLTQDKKIHTGEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAF--- 462
Query: 579 GHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPK 637
+R +H+ SH R++ KP K GK ++ + I + +P
Sbjct: 463 -NRSSHLTSH------RRIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGE----KPYKC 511
Query: 638 NQFFQSYF------NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCG 691
+ +++ + ++ ++PYKC C +A+ +S L QH + HTGEKP+KC QC
Sbjct: 512 EECGKAFILSSRLTQHKKIHTGEKPYKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCD 571
Query: 692 RGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFK 751
+ F + L +H + H+G K +KC C AF L +H IH +PY C C K F
Sbjct: 572 KAFTHSSNLSSHKKIHSGEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFT 631
Query: 752 TSLNCKKHMKTHR 764
S +H K HR
Sbjct: 632 RSSRLTQHKKIHR 644
Score = 192 bits (489), Expect = 2e-48
Identities = 110/329 (33%), Positives = 153/329 (46%), Gaps = 34/329 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F +SS L +H + HTGE+PYK + CGR F S L +K HTG K ++
Sbjct: 367 KPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYN 426
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C FT + +LTRH H KPYKC C + F + H H + H TG
Sbjct: 427 CEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIH---------TG 477
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E + C + ++ S+ N+ +K + EE + A + L Q
Sbjct: 478 EKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGK---------AFILSSRLTQH- 527
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
K+ ++P C C K+F + S L +H +IHTGEKPYKC +C K+
Sbjct: 528 -----------KKIHTGEKPYK---CEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKA 573
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
FT S L H K H+G+K + C C AF+ L H ++HT KP+KC C F S
Sbjct: 574 FTHSSNLSSHKKIHSGEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRS 633
Query: 1264 GRRKTHMQFHYKPDPKKARKPMTRSSSEG 1292
R H + H A P T G
Sbjct: 634 SRLTQHKKIHRMGVVAHACNPSTLGGRGG 662
Score = 191 bits (484), Expect = 7e-48
Identities = 163/660 (24%), Positives = 268/660 (40%), Gaps = 111/660 (16%)
Query: 93 PTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQ 152
P C +K +K H M+ E ++CS ++F + + ++ R
Sbjct: 50 PDLITCLEKEKEPCKMKRHEMVDEPP--VVCSHFAEDFWPEQDIKDSFQKVTLRRYDKRG 107
Query: 153 HACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQL 212
H +K ++T + K + + + T + ++ Y C K F S
Sbjct: 108 HENLQLRKGYKTVGDCKLYKGGYNGLNQCLTLTQSK-------MYHCDIYVKVFYAFSNA 160
Query: 213 TRHIRIHTGERPFKCSECGK----------------------------AFNQKGALQTHM 244
R+ HTG++PF+C +CGK AFNQ AL H
Sbjct: 161 DRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHK 220
Query: 245 IKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHI 304
+ GEK + C C AF+ L +H +R+H+ K Y C EC F +L TH
Sbjct: 221 RIYVGEKHYRCEECGKAFNHYSTLTNH-KRIHTGEK---PYKCKECGKAFSRYSTLTTH- 275
Query: 305 SKMHMG---------GPQNSTSSTETAHVLTATLFQTLPLQQTE-AQATSASSQPSSQAV 354
++H G G S SST T H + T + P + E +A + SS
Sbjct: 276 KRIHSGEKPYKCDECGKTFSISSTFTKHKIIHT--EEKPYKCKECGKAFNRSS------- 326
Query: 355 SDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDS 414
L+ + +G+ P ++ + + + + ++G
Sbjct: 327 --------TLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTG------------- 365
Query: 415 CHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIR 474
P+ + + N+ + T ++ E P K +K + + S L +
Sbjct: 366 -----EKPY-KCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGR--VFTCSSTLTQDKK 417
Query: 475 EENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTG 534
G + + C C K F S L RH RIHT EKP+KC +C +AF S LT+H + HTG
Sbjct: 418 IHTGEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTG 477
Query: 535 IKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTEL 594
K +KC+ C K+F S +L H ++H+G +P+ C C K F S H
Sbjct: 478 EKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQH---------- 527
Query: 595 RKMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNN----- 648
+K+ KP K GK + + I + +P Q +++ +++
Sbjct: 528 KKIHTGEKPYKCEECGKAFNRSSRLTQHKKIHTGE----KPYKCKQCDKAFTHSSNLSSH 583
Query: 649 -FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707
++ ++PYKC C +A+ +S L QH + HT EKP+KC +C + F + L H + H
Sbjct: 584 KKIHSGEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIH 643
Score = 179 bits (455), Expect = 2e-44
Identities = 99/288 (34%), Positives = 147/288 (51%), Gaps = 23/288 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + S+ RH + H ++P++ ++C + F LT K H+GE P C
Sbjct: 369 YKCEECGKAFNQSSRLTRHKKIHT-GEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYNC 427
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+ ++L H +H +E+ C+ECG F S H+ HR+ G + + C
Sbjct: 428 EECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSS----HLTSHRRIHTGEKPYKC 483
Query: 156 KACKKEFETSSELKEHMKTH-----YKIR-------VSSTRSYNRNIDRSGFTYSCPHCG 203
+ C K F+ SS L H K H YK +SS + ++ I Y C CG
Sbjct: 484 EECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKIHTGEKPYKCEECG 543
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F + S+LT+H +IHTGE+P+KC +C KAF L +H H+GEKP+ C C AF+
Sbjct: 544 KAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHSGEKPYKCEECGKAFN 603
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGG 311
+ L H +++H+ K Y C EC+ F L H K+H G
Sbjct: 604 RSSRLTQH-KKIHTREK---PYKCEECAKAFTRSSRLTQH-KKIHRMG 646
Score = 178 bits (452), Expect = 4e-44
Identities = 100/302 (33%), Positives = 143/302 (47%), Gaps = 25/302 (8%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C K F + S L H RIH+ EKP+KC +C + F++ ST T H HT
Sbjct: 249 RIHTGEKPYKCKECGKAFSRYSTLTTHKRIHSGEKPYKCDECGKTFSISSTFTKHKIIHT 308
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH----- 588
K +KC+ C K+F+ S +L H R+HTG +P+ C C K F S H H
Sbjct: 309 EEKPYKCKECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKP 368
Query: 589 FKHTELRKMRHQR----KPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSY 644
+K E K +Q + K+ G +EP G + +
Sbjct: 369 YKCEECGKAFNQSSRLTRHKKIHTG-----------EEPYKFEKCGRVFTCSS-----TL 412
Query: 645 FNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHI 704
+ ++ ++PY C C + + S L +H R HT EKP+KC++CG+ F + L +H
Sbjct: 413 TQDKKIHTGEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHR 472
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR 764
R HTG K +KC C AF +L H IH+ +PY C C K F S +H K H
Sbjct: 473 RIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKIHT 532
Query: 765 YE 766
E
Sbjct: 533 GE 534
Score = 178 bits (452), Expect = 4e-44
Identities = 110/341 (32%), Positives = 160/341 (46%), Gaps = 31/341 (9%)
Query: 448 QESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHE 507
+E P K KE +S L R G + + C C K F S L +H IHT E
Sbjct: 309 EEKPYKC--KECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGE 366
Query: 508 KPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFA 567
KP+KC +C +AF S LT H K HTG + +K + C + F+ S +L ++HTG +P+
Sbjct: 367 KPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYN 426
Query: 568 CPHCDKKFRTSG----HRKTHIASH-FKHTE----LRKMRHQRKPAKVRVGKTNIPVPDI 618
C C K F S H++ H +K E + H ++ G
Sbjct: 427 CEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSHRRIHTG--------- 477
Query: 619 PLQEPILITDLGLIQPIPKNQFFQSYFNNNF--VNEADRPYKCFYCHRAYKKSCHLKQHI 676
++P + G F QS N+ ++ ++PYKC C +A+ S L QH
Sbjct: 478 --EKPYKCEECG-------KAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHK 528
Query: 677 RSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
+ HTGEKP+KC +CG+ F + L H + HTG K +KC C+ AFT +L H IH+
Sbjct: 529 KIHTGEKPYKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHS 588
Query: 737 DLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQA 777
+PY C C K F S +H K H E + ++ +A
Sbjct: 589 GEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKA 629
Score = 152 bits (383), Expect = 4e-36
Identities = 94/330 (28%), Positives = 132/330 (40%), Gaps = 63/330 (19%)
Query: 964 RRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF 1023
++ ++C C K F S L QH + H E Y+CK G F S L +H++ + G K +
Sbjct: 170 KKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHKRIYVGEKHY 229
Query: 1024 SCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSAT 1083
C C +F +LT H H KPYKC C + F H + H +
Sbjct: 230 RCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIH---------S 280
Query: 1084 GETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
GE +P + + + S
Sbjct: 281 GE-----------------------------------------KPYKCDECGKTFSISST 299
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
K +I +K + C C K+F + S L H RIHTGEKPYKC+ECGK+
Sbjct: 300 FTKHKIIHTEEKPYK----------CKECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKA 349
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTS 1263
F STL H HTG+K + C C AF+ L H ++HTG +P+K C F S
Sbjct: 350 FNWSSTLTKHKVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCS 409
Query: 1264 GRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
+ H P ++ K T SS+
Sbjct: 410 STLTQDKKIHTGEKPYNCEECGKVFTYSST 439
Score = 132 bits (332), Expect = 3e-30
Identities = 70/173 (40%), Positives = 100/173 (57%), Gaps = 11/173 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE +V S L + E + ++C EC +AF+ ++ L H + +H E+ + C
Sbjct: 427 CEECG-KVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTSH-RRIHTGEKPYKCE 484
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAFK++++L H + H S +KP +KC+ C KAF S+L +H +IHTGE+P
Sbjct: 485 ECGKAFKQSSNLNSHKKIH------SGEKP--YKCEECGKAFILSSRLTQHKKIHTGEKP 536
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+ C C KAFN+ S L H K HTGE+PYKC C FT SN+ H K+ HS
Sbjct: 537 YKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSH-KKIHS 588
Score = 125 bits (313), Expect = 5e-28
Identities = 87/322 (27%), Positives = 124/322 (38%), Gaps = 32/322 (9%)
Query: 962 QSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVK 1021
Q R+ Y+ K +K + + T K Y C + + F + ++ HTG K
Sbjct: 112 QLRKGYKTVGDCKLYKGGYNGLNQCLTLTQSKMYHCDIYVKVFYAFSNADRYKTRHTGKK 171
Query: 1022 AFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVS 1081
F C C SF LT+H H+ Y+C F + H + +
Sbjct: 172 PFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHKRIYVG------ 225
Query: 1082 ATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQ 1141
E+H K+ T T + + +P + +
Sbjct: 226 ---------------EKHYRCEECGKAFNHYSTLTNHKRIHTGE-KPYKCKECGKAF--- 266
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECG 1201
R S L + E + C C K+F S +H IHT EKPYKC ECG
Sbjct: 267 -----SRYSTLTTHKRIHSGEKPYK--CDECGKTFSISSTFTKHKIIHTEEKPYKCKECG 319
Query: 1202 KSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFR 1261
K+F STL H + HTG+K + C C AF+ +L H +HTG KP+KC C F
Sbjct: 320 KAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFN 379
Query: 1262 TSGRRKTHMQFHYKPDPKKARK 1283
S R H + H +P K K
Sbjct: 380 QSSRLTRHKKIHTGEEPYKFEK 401
Score = 122 bits (306), Expect = 3e-27
Identities = 64/169 (37%), Positives = 92/169 (54%), Gaps = 10/169 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + + ++C EC +AF ++ L H K++H E+ + C
Sbjct: 483 CEECG-KAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQH-KKIHTGEKPYKCE 540
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF R++ L +H + H + +KP +KC C+KAF S L H +IH+GE+P
Sbjct: 541 ECGKAFNRSSRLTQHKKIH------TGEKP--YKCKQCDKAFTHSSNLSSHKKIHSGEKP 592
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
+ C C KAFN+ S L H K HT E+PYKC C FT+ S + H K
Sbjct: 593 YKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKK 641
Score = 118 bits (296), Expect = 5e-26
Identities = 56/144 (38%), Positives = 85/144 (59%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF ++ L H K++H E+ + C C KAF ++ L +H + H
Sbjct: 479 KPYKCEECGKAFKQSSNLNSH-KKIHSGEKPYKCEECGKAFILSSRLTQHKKIH------ 531
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C KAF + S+L +H +IHTGE+P+ C C+KAF S L H K H+G
Sbjct: 532 TGEKP--YKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHSG 589
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C F + S + H K
Sbjct: 590 EKPYKCEECGKAFNRSSRLTQHKK 613
Score = 113 bits (283), Expect = 1e-24
Identities = 58/144 (40%), Positives = 77/144 (53%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AFS + L H K +H E+ + C C K F ++ +H H
Sbjct: 255 KPYKCKECGKAFSRYSTLTTH-KRIHSGEKPYKCDECGKTFSISSTFTKHKIIH------ 307
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF + S L H RIHTGE+P+ C C KAFN S L H HTG
Sbjct: 308 TEEKP--YKCKECGKAFNRSSTLTSHKRIHTGEKPYKCEECGKAFNWSSTLTKHKVIHTG 365
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PYKC C F Q S + H K
Sbjct: 366 EKPYKCEECGKAFNQSSRLTRHKK 389
Score = 112 bits (280), Expect = 3e-24
Identities = 69/267 (25%), Positives = 102/267 (38%), Gaps = 45/267 (16%)
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVR 564
T K + C + F S + HTG K F+C+ C KSF L H ++H
Sbjct: 140 TQSKMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIREN 199
Query: 565 PFACPHCDKKFRTSG----HRKTHIAS-HFKHTELRKMRHQRKPAKVRVGKTNIPVPDIP 619
+ C F S H++ ++ H++ E K +
Sbjct: 200 TYRCKEFGNAFNQSSALTNHKRIYVGEKHYRCEECGKAFNH------------------- 240
Query: 620 LQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSH 679
+ + N+ ++ ++PYKC C +A+ + L H R H
Sbjct: 241 ---------------------YSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIH 279
Query: 680 TGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLR 739
+GEKP+KC +CG+ F + H HT K +KC C AF +L H IH +
Sbjct: 280 SGEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGEK 339
Query: 740 PYMCPYCQKTFKTSLNCKKHMKTHRYE 766
PY C C K F S KH H E
Sbjct: 340 PYKCEECGKAFNWSSTLTKHKVIHTGE 366
Score = 112 bits (280), Expect = 3e-24
Identities = 59/168 (35%), Positives = 84/168 (50%), Gaps = 22/168 (13%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K +H E+ + C C KAF +++ L H + H
Sbjct: 339 KPYKCEECGKAFNWSSTLTKH-KVIHTGEKPYKCEECGKAFNQSSRLTRHKKIHTGEEPY 397
Query: 1715 SSQK--------------------PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
+K + + C+ C K F S L RH RIHT E+P+ C
Sbjct: 398 KFEKCGRVFTCSSTLTQDKKIHTGEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNE 457
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
C KAFN+ S L H + HTGE+PYKC C F Q SN+ H K+ HS
Sbjct: 458 CGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAFKQSSNLNSH-KKIHS 504
Score = 108 bits (271), Expect = 4e-23
Identities = 62/175 (35%), Positives = 92/175 (52%), Gaps = 15/175 (8%)
Query: 1653 EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGP 1712
E + ++C EC +AF+ ++ L H K +H E+ + C C KAF ++ L +H H
Sbjct: 309 EEKPYKCKECGKAFNRSSTLTSH-KRIHTGEKPYKCEECGKAFNWSSTLTKHKVIH---- 363
Query: 1713 SLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
+ +KP +KC+ C KAF + S+L RH +IHTGE P+ C + F S L K H
Sbjct: 364 --TGEKP--YKCEECGKAFNQSSRLTRHKKIHTGEEPYKFEKCGRVFTCSSTLTQDKKIH 419
Query: 1773 TGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHL 1827
TGE+PY C C FT S + H KR H+ +E + G+ +R+ HL
Sbjct: 420 TGEKPYNCEECGKVFTYSSTLTRH-KRIHT-----EEKPYKCNECGKAFNRSSHL 468
Score = 103 bits (257), Expect = 2e-21
Identities = 65/238 (27%), Positives = 90/238 (37%), Gaps = 39/238 (16%)
Query: 531 THTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFK 590
T T K + C +K F + + HTG +PF C C K F H H +
Sbjct: 138 TLTQSKMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIR 197
Query: 591 HTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQS--YFNNN 648
R + G N F QS N+
Sbjct: 198 ENTYR------------------------------CKEFG-------NAFNQSSALTNHK 220
Query: 649 FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHT 708
+ ++ Y+C C +A+ L H R HTGEKP+KC +CG+ F L H R H+
Sbjct: 221 RIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIHS 280
Query: 709 GLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
G K +KC C F+ + +H IH + +PY C C K F S H + H E
Sbjct: 281 GEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGE 338
Score = 97.1 bits (240), Expect = 1e-19
Identities = 49/139 (35%), Positives = 73/139 (52%), Gaps = 9/139 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
QC +C ++F + L H K++H RE + C AF +++ L H + +
Sbjct: 174 QCKKCGKSFCMLSQLTQH-KKIHIRENTYRCKEFGNAFNQSSALTNHKRIYVG------- 225
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
+ ++C+ C KAF S L H RIHTGE+P+ C C KAF++ S L H + H+GE+P
Sbjct: 226 -EKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIHSGEKP 284
Query: 1778 YKCAYCVMGFTQKSNMKLH 1796
YKC C F+ S H
Sbjct: 285 YKCDECGKTFSISSTFTKH 303
Score = 91.7 bits (226), Expect = 6e-18
Identities = 45/118 (38%), Positives = 70/118 (59%), Gaps = 9/118 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L H K++H E+ + C C KAF +++L H + H
Sbjct: 535 KPYKCEECGKAFNRSSRLTQH-KKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIH------ 587
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
S +KP +KC+ C KAF + S+L +H +IHT E+P+ C C KAF + S L H K H
Sbjct: 588 SGEKP--YKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIH 643
Score = 89.0 bits (219), Expect = 4e-17
Identities = 46/120 (38%), Positives = 64/120 (53%), Gaps = 5/120 (4%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + S+ +H + H +KP++C QC + F NL+ HK HSGE P C
Sbjct: 537 YKCEECGKAFNRSSRLTQHKKIHT-GEKPYKCKQCDKAFTHSSNLSSHKKIHSGEKPYKC 595
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+R + L H +H +E+ C EC FT S+L H + HR G HAC
Sbjct: 596 EECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIHRM---GVVAHAC 652
Score = 82.4 bits (202), Expect = 4e-15
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 13/138 (9%)
Query: 1665 AFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKC 1724
AFS+A K H ++ C C K+F + L +H + H + ++C
Sbjct: 156 AFSNA----DRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHI--------RENTYRC 203
Query: 1725 DTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCV 1784
AF + S L H RI+ GE+ + C C KAFN S L H + HTGE+PYKC C
Sbjct: 204 KEFGNAFNQSSALTNHKRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECG 263
Query: 1785 MGFTQKSNMKLHMKRAHS 1802
F++ S + H KR HS
Sbjct: 264 KAFSRYSTLTTH-KRIHS 280
Score = 71.6 bits (174), Expect = 7e-12
Identities = 35/129 (27%), Positives = 56/129 (43%)
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+P++C C +++ L QH + H E ++C + G F + L H R + G K ++
Sbjct: 171 KPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHKRIYVGEKHYR 230
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
C C AF +L H IH +PY C C K F H + H E + +
Sbjct: 231 CEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIHSGEKPYKCDEC 290
Query: 775 QQAASIDDS 783
+ SI +
Sbjct: 291 GKTFSISST 299
Score = 60.1 bits (144), Expect = 2e-08
Identities = 31/123 (25%), Positives = 52/123 (42%)
Query: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716
Y C + + + ++ HTG+KPF+C +CG+ F L H + H +++C
Sbjct: 145 YHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCK 204
Query: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQ 776
AF +L H I+ + Y C C K F H + H E + ++ +
Sbjct: 205 EFGNAFNQSSALTNHKRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGK 264
Query: 777 AAS 779
A S
Sbjct: 265 AFS 267
Score = 56.2 bits (134), Expect = 3e-07
Identities = 28/85 (32%), Positives = 41/85 (48%)
Query: 1714 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
L+ + +++ CD K F S +R+ HTG++PF C C K+F S L H K H
Sbjct: 137 LTLTQSKMYHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHI 196
Query: 1774 GERPYKCAYCVMGFTQKSNMKLHMK 1798
E Y+C F Q S + H +
Sbjct: 197 RENTYRCKEFGNAFNQSSALTNHKR 221
Score = 52.4 bits (124), Expect = 4e-06
Identities = 24/71 (33%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL+ + + ++C EC +AF+ ++ L H K++H RE+ + C C KAF R++
Sbjct: 577 SSNLSSHKKIHSGEKPYKCEECGKAFNRSSRLTQH-KKIHTREKPYKCEECAKAFTRSSR 635
Query: 1701 LKEHMQTHQAG 1711
L +H + H+ G
Sbjct: 636 LTQHKKIHRMG 646
>gi|223468695 zinc finger protein 572 [Homo sapiens]
Length = 529
Score = 214 bits (545), Expect = 6e-55
Identities = 125/318 (39%), Positives = 160/318 (50%), Gaps = 32/318 (10%)
Query: 956 LEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEK 1015
+ + + Y+C C K F SSHL QH RSHTGEKPY+C +CG+GF S VL H++
Sbjct: 205 IHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQR 264
Query: 1016 THTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQT 1075
THTG K + C C SF+ + SL RH TH KPYKC CE+ F KH + H
Sbjct: 265 THTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIH-- 322
Query: 1076 VPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVS 1135
TGE C E +N SR S +IT + T + + ES+
Sbjct: 323 -------TGEKPYQ--CPE-----CGKNFSRSS--NLITHQKMHTGE----KSYESSEYE 362
Query: 1136 EKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
E S + + E + +Q K CC C KSF S L+RH R HTGEKPY
Sbjct: 363 E-----SLGQNCNVIE----ECRIQLGEKPYRCCE-CGKSFGLSSHLIRHQRTHTGEKPY 412
Query: 1196 KCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPH 1255
+C EC K+F+ STL H +THTG+K + C C +FS +L H R H G KP+KC
Sbjct: 413 RCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTS 472
Query: 1256 CELRFRTSGRRKTHMQFH 1273
CE F S H + H
Sbjct: 473 CEKCFSRSAYLSQHRKIH 490
Score = 191 bits (484), Expect = 7e-48
Identities = 114/375 (30%), Positives = 168/375 (44%), Gaps = 42/375 (11%)
Query: 939 QESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCK 998
++ + +E D + ++ N R Y+C C K F SSHL+ H R+H+GEKPYKC
Sbjct: 104 EKPNHQEWDSGEHTNACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCS 163
Query: 999 LCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEE 1058
C + F +S L H + HTG K + C C SF+ L H TH KPYKCP C +
Sbjct: 164 ECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGK 223
Query: 1059 GFRTTVHCKKHMKRHQ-TVPSAVSATGE-TEGGDICMEEEEEHSDRNASRKSRPEVITFT 1116
F ++ H +H + H P S G+ + +E + H+ +P
Sbjct: 224 RFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTG------EKPYKCPDC 277
Query: 1117 EEETAQLAKIRPQESATVSEKVLVQSAAEKD---RISELRDKQAELQDEPKHANCCTYCP 1173
+ +Q + + + EK EK + ++ ++ ++P C C
Sbjct: 278 GKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQ---CPECG 334
Query: 1174 KSFKKPSDLVRHVRIHT----------------------------GEKPYKCDECGKSFT 1205
K+F + S+L+ H ++HT GEKPY+C ECGKSF
Sbjct: 335 KNFSRSSNLITHQKMHTGEKSYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFG 394
Query: 1206 VKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGR 1265
+ S L H +THTG+K + C C FS +L +H R HTG KP+KCP C F S
Sbjct: 395 LSSHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFN 454
Query: 1266 RKTHMQFHYKPDPKK 1280
H + H P K
Sbjct: 455 LIRHRRTHIGEKPYK 469
Score = 187 bits (476), Expect = 6e-47
Identities = 109/316 (34%), Positives = 159/316 (50%), Gaps = 29/316 (9%)
Query: 473 IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532
+R G + + C C K F S L+ H R HT EKP+KCP+C + F+ S L H ++H
Sbjct: 179 LRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSH 238
Query: 533 TGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH 588
TG K ++C C K FS S L H R HTG +P+ CP C K F S H++TH
Sbjct: 239 TGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEK 298
Query: 589 -FKHTELRK--------MRHQRKPAKVRVGKTNIPVPDIPL---QEPILITDLGLI---Q 633
+K E K ++HQR + G+ P+ + LIT + +
Sbjct: 299 PYKCLECEKSFGCNSTLIKHQR----IHTGEKPYQCPECGKNFSRSSNLITHQKMHTGEK 354
Query: 634 PIPKNQFFQSYFNN-NFVNEA-----DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKC 687
+++ +S N N + E ++PY+C C +++ S HL +H R+HTGEKP++C
Sbjct: 355 SYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTHTGEKPYRC 414
Query: 688 SQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQ 747
S+C + F + L H RTHTG K +KC C +F+ +L RH H +PY C C+
Sbjct: 415 SECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTSCE 474
Query: 748 KTFKTSLNCKKHMKTH 763
K F S +H K H
Sbjct: 475 KCFSRSAYLSQHRKIH 490
Score = 172 bits (437), Expect = 2e-42
Identities = 106/303 (34%), Positives = 138/303 (45%), Gaps = 23/303 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C F S +H R H +KP+ C C + F+ + L H+ TH+GE P C
Sbjct: 216 YKCPECGKRFSSSSHLIQHHRSHT-GEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKC 274
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
P C K FS+ +SL H H E+ C EC F S L H H G + + C
Sbjct: 275 PDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIH----TGEKPYQC 330
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFT------------YSCPHCG 203
C K F SS L H K H + + Y ++ ++ Y C CG
Sbjct: 331 PECGKNFSRSSNLITHQKMHTGEKSYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECG 390
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K+F S L RH R HTGE+P++CSEC K F+Q L H HTGEKP+ C C +FS
Sbjct: 391 KSFGLSSHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFS 450
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAH 323
Q NL H +R H K Y CT C F L+ H K+H+ P S + H
Sbjct: 451 QSFNLIRH-RRTHIGEK---PYKCTSCEKCFSRSAYLSQH-RKIHVEKPFESPDVGDFPH 505
Query: 324 VLT 326
T
Sbjct: 506 EWT 508
Score = 170 bits (430), Expect = 1e-41
Identities = 97/317 (30%), Positives = 149/317 (47%), Gaps = 47/317 (14%)
Query: 486 YCAKEFRKPSDLVRHIRIHTH----------EKPFKCPQCFRAFAVKSTLTAHIKTHTGI 535
+ AKE KP+ HT+ ++P+KC +C+++F+ S L H +TH+G
Sbjct: 98 FIAKEEEKPNHQEWDSGEHTNACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGE 157
Query: 536 KAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595
K +KC C K F S L H+R+HTG +P+ C C K F + H H +H
Sbjct: 158 KPYKCSECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGE---- 213
Query: 596 KMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEAD 654
KP K GK + LIQ ++ + +
Sbjct: 214 ------KPYKCPECGKR-------------FSSSSHLIQ-------------HHRSHTGE 241
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+PY+C C + + S L +H R+HTGEKP+KC CG+ F + L H RTHTG K +K
Sbjct: 242 KPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEKPYK 301
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
CL C +F +L +H IH +PY CP C K F S N H K H E + + ++
Sbjct: 302 CLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLITHQKMHTGEKSYESSEY 361
Query: 775 QQAASIDDSTVDQQSMQ 791
+++ + + +++ +Q
Sbjct: 362 EESLGQNCNVIEECRIQ 378
Score = 167 bits (422), Expect = 1e-40
Identities = 102/331 (30%), Positives = 141/331 (42%), Gaps = 67/331 (20%)
Query: 480 RWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK 539
R + C C K F S L H R H+ EKP+KC +C + F S L H++ HTG K ++
Sbjct: 130 RPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHLRMHTGEKPYQ 189
Query: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH----------- 588
C C KSFS + L +H R HTG +P+ CP C K+F +S H H SH
Sbjct: 190 CGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTGEKPYECSVC 249
Query: 589 ---FKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQ--S 643
F H+ + + HQR G+ PD F Q S
Sbjct: 250 GKGFSHSYV-LIEHQR----THTGEKPYKCPDC------------------GKSFSQSSS 286
Query: 644 YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAH 703
+ + ++PYKC C +++ + L +H R HTGEKP++C +CG+ F + L H
Sbjct: 287 LIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLITH 346
Query: 704 IRTHTGLKS----------------------------FKCLICNGAFTTGGSLRRHMGIH 735
+ HTG KS ++C C +F L RH H
Sbjct: 347 QKMHTGEKSYESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTH 406
Query: 736 NDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE 766
+PY C C KTF S H +TH E
Sbjct: 407 TGEKPYRCSECWKTFSQSSTLVIHQRTHTGE 437
Score = 164 bits (414), Expect = 1e-39
Identities = 94/265 (35%), Positives = 127/265 (47%), Gaps = 28/265 (10%)
Query: 23 NAENTNYAYQ-----VPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNV 77
+ E+TN Q V +KC C SF S + H R H +KP++C +C + F
Sbjct: 113 SGEHTNACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHS-GEKPYKCSECAKCFCN 171
Query: 78 EFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQL 136
+L H H+GE P C C K FS + L H H E+ C ECG F+ S
Sbjct: 172 SSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSS-- 229
Query: 137 AVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFT 196
H+ +H + G + + C C K F S L EH +TH +
Sbjct: 230 --HLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEK----------------P 271
Query: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACA 256
Y CP CGK+F + S L RH R HTGE+P+KC EC K+F L H HTGEKP+ C
Sbjct: 272 YKCPDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCP 331
Query: 257 FCPAAFSQKGNLQSHVQRVHSEVKN 281
C FS+ NL +H Q++H+ K+
Sbjct: 332 ECGKNFSRSSNLITH-QKMHTGEKS 355
Score = 145 bits (365), Expect = 5e-34
Identities = 88/279 (31%), Positives = 124/279 (44%), Gaps = 38/279 (13%)
Query: 536 KAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595
+ +KC C KSFS S L+ H R H+G +P+ C C K F S H H+
Sbjct: 130 RPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHL---------- 179
Query: 596 KMRHQRKPAKV-RVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEAD 654
+M KP + GK+ + + E + +
Sbjct: 180 RMHTGEKPYQCGECGKSFSNTSHLIIHER--------------------------THTGE 213
Query: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
+PYKC C + + S HL QH RSHTGEKP++CS CG+GF + VL H RTHTG K +K
Sbjct: 214 KPYKCPECGKRFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYK 273
Query: 715 CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQH 774
C C +F+ SL RH H +PY C C+K+F + KH + H E Q +
Sbjct: 274 CPDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPEC 333
Query: 775 QQAASIDDSTVDQQSMQASTQMQVEIESDE-LPQTAEVV 812
+ S + + Q M + E +E L Q V+
Sbjct: 334 GKNFSRSSNLITHQKMHTGEKSYESSEYEESLGQNCNVI 372
Score = 144 bits (364), Expect = 6e-34
Identities = 108/403 (26%), Positives = 169/403 (41%), Gaps = 49/403 (12%)
Query: 222 ERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKN 281
+RP+KCSEC K+F+ L+TH H+GEKP+ C+ C F +L H+ R+H+ K
Sbjct: 129 DRPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHL-RMHTGEK- 186
Query: 282 GPTYNCTECSCVFKSLGSL----NTHISKMHMGGPQNSTSSTETAHVLTATLFQT--LPL 335
Y C EC F + L TH + P+ + ++H++ T P
Sbjct: 187 --PYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTGEKPY 244
Query: 336 QQT-------------EAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQ 381
+ + E Q T +P Q L +G+ P +
Sbjct: 245 ECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEKPYKCLE 304
Query: 382 LSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
+ G N +++ ++G + C S S++ Q T
Sbjct: 305 CEKSFGCNSTLIKHQRIHTG-----EKPYQCPECGKNFSRS-------SNLITHQKMHTG 352
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
+ + E E L + + R + G + + C C K F S L+RH
Sbjct: 353 EKSYESSEYEESLGQNCNVI---------EECRIQLGEKPYRCCECGKSFGLSSHLIRHQ 403
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
R HT EKP++C +C++ F+ STL H +THTG K +KC C +SFS S +L H R H
Sbjct: 404 RTHTGEKPYRCSECWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHI 463
Query: 562 GVRPFACPHCDKKFRTSG----HRKTHIASHFKHTELRKMRHQ 600
G +P+ C C+K F S HRK H+ F+ ++ H+
Sbjct: 464 GEKPYKCTSCEKCFSRSAYLSQHRKIHVEKPFESPDVGDFPHE 506
Score = 124 bits (311), Expect = 8e-28
Identities = 98/406 (24%), Positives = 151/406 (37%), Gaps = 69/406 (16%)
Query: 151 RQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPS 210
R + C C K F SS L+ H +TH + Y C C K F S
Sbjct: 130 RPYKCSECWKSFSNSSHLRTHQRTHSGEK----------------PYKCSECAKCFCNSS 173
Query: 211 QLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQ------ 264
L +H+R+HTGE+P++C ECGK+F+ L H HTGEKP+ C C FS
Sbjct: 174 HLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQ 233
Query: 265 -----------------KGNLQSHVQRVHSEVKNG-PTYNCTECSCVFKSLGSLNTHISK 306
KG S+V H G Y C +C F SL H +
Sbjct: 234 HHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRH-QR 292
Query: 307 MHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSE 366
H G E + +TL + + E + S++I
Sbjct: 293 THTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLITH------ 346
Query: 367 PAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQN 426
+ +G+ + ++G N +++++ I P C S +
Sbjct: 347 -QKMHTGEKSYESSEYEESLGQNCNVIEEC-------RIQLGEKPYRCCECGKSFGLS-- 396
Query: 427 PDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPY 486
S + Q T + + E + + +I + R G + + CP
Sbjct: 397 ---SHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQ---------RTHTGEKPYKCPD 444
Query: 487 CAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532
C + F + +L+RH R H EKP+KC C + F+ + L+ H K H
Sbjct: 445 CGESFSQSFNLIRHRRTHIGEKPYKCTSCEKCFSRSAYLSQHRKIH 490
Score = 119 bits (297), Expect = 4e-26
Identities = 58/144 (40%), Positives = 85/144 (59%), Gaps = 9/144 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC + FSS++ L+ H + H E+ + C VC K F + L EH +TH
Sbjct: 214 KPYKCPECGKRFSSSSHLIQHHRS-HTGEKPYECSVCGKGFSHSYVLIEHQRTH------ 266
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C K+F++ S L RH R HTGE+P+ C CEK+F S L H + HTG
Sbjct: 267 TGEKP--YKCPDCGKSFSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTG 324
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMK 1798
E+PY+C C F++ SN+ H K
Sbjct: 325 EKPYQCPECGKNFSRSSNLITHQK 348
Score = 117 bits (292), Expect = 1e-25
Identities = 57/138 (41%), Positives = 75/138 (54%)
Query: 940 ESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKL 999
ESS+ E L + E + YRC C K F SSHL +H R+HTGEKPY+C
Sbjct: 357 ESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTHTGEKPYRCSE 416
Query: 1000 CGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEG 1059
C + F S L H++THTG K + C C SF+ + +L RH TH+ KPYKC CE+
Sbjct: 417 CWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTSCEKC 476
Query: 1060 FRTTVHCKKHMKRHQTVP 1077
F + + +H K H P
Sbjct: 477 FSRSAYLSQHRKIHVEKP 494
Score = 115 bits (289), Expect = 3e-25
Identities = 57/167 (34%), Positives = 88/167 (52%), Gaps = 22/167 (13%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++CLEC+++F + L+ H + +H E+ + CP C K F R+++L H + H S
Sbjct: 298 KPYKCLECEKSFGCNSTLIKHQR-IHTGEKPYQCPECGKNFSRSSNLITHQKMHTGEKSY 356
Query: 1715 SSQK--------------------PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTL 1754
S + + ++C C K+F S L RH R HTGE+P+ C+
Sbjct: 357 ESSEYEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTHTGEKPYRCSE 416
Query: 1755 CEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAH 1801
C K F+Q S L +H + HTGE+PYKC C F+Q N+ H +R H
Sbjct: 417 CWKTFSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRH-RRTH 462
Score = 107 bits (267), Expect = 1e-22
Identities = 53/148 (35%), Positives = 86/148 (58%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
R ++C EC ++FS+++ L H + H E+ + C C K F ++HL +H++ H
Sbjct: 130 RPYKCSECWKSFSNSSHLRTHQR-THSGEKPYKCSECAKCFCNSSHLIQHLRMH------ 182
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP ++C C K+F+ S L H R HTGE+P+ C C K F+ S L H + HTG
Sbjct: 183 TGEKP--YQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTG 240
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY+C+ C GF+ S + + +R H+
Sbjct: 241 EKPYECSVCGKGFSH-SYVLIEHQRTHT 267
Score = 104 bits (260), Expect = 7e-22
Identities = 61/169 (36%), Positives = 90/169 (53%), Gaps = 14/169 (8%)
Query: 1634 AYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRK 1693
+Y+ G S N E+E HQ E D + A + +S V +R + C C K
Sbjct: 85 SYESDGKSENWGNFIAKEEEKPNHQ--EWDSGEHTNACVQQNSSFV---DRPYKCSECWK 139
Query: 1694 AFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCT 1753
+F ++HL+ H +TH S +KP +KC C K F S L +H R+HTGE+P+ C
Sbjct: 140 SFSNSSHLRTHQRTH------SGEKP--YKCSECAKCFCNSSHLIQHLRMHTGEKPYQCG 191
Query: 1754 LCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
C K+F+ S L +H + HTGE+PYKC C F+ S++ H R+H+
Sbjct: 192 ECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQH-HRSHT 239
Score = 85.5 bits (210), Expect = 4e-16
Identities = 42/125 (33%), Positives = 72/125 (57%), Gaps = 10/125 (8%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC ++F ++ L+ H + H E+ + C C K F +++ L H +TH
Sbjct: 382 KPYRCCECGKSFGLSSHLIRHQR-THTGEKPYRCSECWKTFSQSSTLVIHQRTH------ 434
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C ++F++ L RH R H GE+P+ CT CEK F++ + L H K H
Sbjct: 435 TGEKP--YKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTSCEKCFSRSAYLSQHRKIHV- 491
Query: 1775 ERPYK 1779
E+P++
Sbjct: 492 EKPFE 496
Score = 82.0 bits (201), Expect = 5e-15
Identities = 43/130 (33%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 1161 DEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQ 1220
D +H N C SF ++PYKC EC KSF+ S L H +TH+G+
Sbjct: 112 DSGEHTNACVQQNSSFV--------------DRPYKCSECWKSFSNSSHLRTHQRTHSGE 157
Query: 1221 KLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKK 1280
K + C C+ F L H+R+HTG KP++C C F + H + H P K
Sbjct: 158 KPYKCSECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYK 217
Query: 1281 ARKPMTRSSS 1290
+ R SS
Sbjct: 218 CPECGKRFSS 227
Score = 82.0 bits (201), Expect = 5e-15
Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 6/123 (4%)
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
SS R +KC C K+F+ S L H R H+GE+P+ C+ C K F S L H++ HTG
Sbjct: 125 SSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHLRMHTG 184
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQEA 1834
E+PY+C C F+ S++ +H +R H+ E + G+ S + HL + +
Sbjct: 185 EKPYQCGECGKSFSNTSHLIIH-ERTHT-----GEKPYKCPECGKRFSSSSHLIQHHRSH 238
Query: 1835 AGE 1837
GE
Sbjct: 239 TGE 241
Score = 66.2 bits (160), Expect = 3e-10
Identities = 35/112 (31%), Positives = 63/112 (56%), Gaps = 10/112 (8%)
Query: 1639 GVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRA 1698
G+S +L + + ++C EC + FS ++ L+ H + H E+ + CP C ++F ++
Sbjct: 394 GLSSHLIRHQRTHTGEKPYRCSECWKTFSQSSTLVIHQR-THTGEKPYKCPDCGESFSQS 452
Query: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPF 1750
+L H +TH +KP +KC +CEK F++ + L +H +IH E+PF
Sbjct: 453 FNLIRHRRTH------IGEKP--YKCTSCEKCFSRSAYLSQHRKIHV-EKPF 495
>gi|148596977 zinc finger protein 31 [Homo sapiens]
Length = 1043
Score = 211 bits (536), Expect = 7e-54
Identities = 119/347 (34%), Positives = 163/347 (46%), Gaps = 44/347 (12%)
Query: 939 QESSQEELD--LQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYK 996
+ SS+E+L+ + QG E + Y+CD C K F +SSH H R HTGEKPYK
Sbjct: 687 ESSSEEDLEKLIDHQGLYLAE-------KPYKCDTCMKSFSRSSHFIAHQRIHTGEKPYK 739
Query: 997 CKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFC 1056
C CG+ F L +H++ HTG K + C C SF+ + +L H H KPYKC C
Sbjct: 740 CLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGEC 799
Query: 1057 EEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFT 1116
+ F + + KH + H GG+ ++ S+ + P
Sbjct: 800 WKSFNQSSNLLKHQRIHL-------------GGN-----PDQCSEPGGNFAQSPSFSAHW 841
Query: 1117 EEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSF 1176
T + A +PQ + S +++ E C+ C +SF
Sbjct: 842 RNSTEETAPEQPQSISKDLNSPGPHSTNSGEKLYE-----------------CSECGRSF 884
Query: 1177 KKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKG 1236
K S L+ H RIHTGEKPY+C ECGKSF+ STL H +THTG+K + C C FS +
Sbjct: 885 SKSSALISHQRIHTGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCGKCFSERS 944
Query: 1237 SLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
L H R+HTG KP+KC C FR TH + H P K R+
Sbjct: 945 KLITHQRVHTGEKPYKCLECGKFFRDRSNLITHQRIHTGEKPYKCRE 991
Score = 180 bits (456), Expect = 1e-44
Identities = 106/327 (32%), Positives = 153/327 (46%), Gaps = 28/327 (8%)
Query: 444 QEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRI 503
QE+ QES + D + K+I + +L + + C C K F + S + H RI
Sbjct: 682 QEQWQESSSEEDLE--KLIDHQGLYL--------AEKPYKCDTCMKSFSRSSHFIAHQRI 731
Query: 504 HTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGV 563
HT EKP+KC +C + F+ +S L H + HTG K +KC C KSFS +L H R+HTG
Sbjct: 732 HTGEKPYKCLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGE 791
Query: 564 RPFACPHCDKKFRTSG----HRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIP 619
+P+ C C K F S H++ H+ + + P+ N P
Sbjct: 792 KPYKCGECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPS-FSAHWRNSTEETAP 850
Query: 620 LQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSH 679
Q + DL P + N ++ Y+C C R++ KS L H R H
Sbjct: 851 EQPQSISKDLNSPGP-------------HSTNSGEKLYECSECGRSFSKSSALISHQRIH 897
Query: 680 TGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLR 739
TGEKP++C++CG+ F + L H RTHTG K +KC+ C F+ L H +H +
Sbjct: 898 TGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEK 957
Query: 740 PYMCPYCQKTFKTSLNCKKHMKTHRYE 766
PY C C K F+ N H + H E
Sbjct: 958 PYKCLECGKFFRDRSNLITHQRIHTGE 984
Score = 171 bits (433), Expect = 6e-42
Identities = 97/284 (34%), Positives = 139/284 (48%), Gaps = 20/284 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C+ SF + S F H R H +KP++C +C + F+ NL H+ H+GE P C
Sbjct: 710 YKCDTCMKSFSRSSHFIAHQRIHT-GEKPYKCLECGKNFSDRSNLNTHQRIHTGEKPYKC 768
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K FS ++L H +H E+ C EC F S L H H G C
Sbjct: 769 LECGKSFSDHSNLITHQRIHTGEKPYKCGECWKSFNQSSNLLKHQRIH----LGGNPDQC 824
Query: 156 KACKKEFETSSELKEHMKTHYKIRV-SSTRSYNRNIDRSG--------FTYSCPHCGKTF 206
F S H + + +S +++++ G Y C CG++F
Sbjct: 825 SEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDLNSPGPHSTNSGEKLYECSECGRSF 884
Query: 207 QKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKG 266
K S L H RIHTGE+P++C+ECGK+F++ L H HTGEKP+ C C FS++
Sbjct: 885 SKSSALISHQRIHTGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCGKCFSERS 944
Query: 267 NLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
L +H QRVH+ K Y C EC F+ +L TH ++H G
Sbjct: 945 KLITH-QRVHTGEK---PYKCLECGKFFRDRSNLITH-QRIHTG 983
Score = 160 bits (406), Expect = 8e-39
Identities = 110/359 (30%), Positives = 157/359 (43%), Gaps = 30/359 (8%)
Query: 433 SNEQTDPTDAEQEKEQ----------ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWH 482
S EQ + +E++ E+ E P K D K + S F+ R G + +
Sbjct: 681 SQEQWQESSSEEDLEKLIDHQGLYLAEKPYKCDTCMKSF-SRSSHFIAHQ-RIHTGEKPY 738
Query: 483 VCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQY 542
C C K F S+L H RIHT EKP+KC +C ++F+ S L H + HTG K +KC
Sbjct: 739 KCLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGE 798
Query: 543 CMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHT------ELRK 596
C KSF+ S +L H R+H G P C F S H + + T + K
Sbjct: 799 CWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISK 858
Query: 597 MRHQRKPAKVRVGKTNIPVPDIPL---QEPILITDLGLI---QPIPKNQFFQSYF----- 645
+ P G+ + + LI+ + +P + +S+
Sbjct: 859 DLNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTGEKPYECAECGKSFSKSSTL 918
Query: 646 -NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHI 704
N+ + ++PYKC C + + + L H R HTGEKP+KC +CG+ F L H
Sbjct: 919 ANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLITHQ 978
Query: 705 RTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTH 763
R HTG K +KC C F SL H IH +PY C C K F S + H +TH
Sbjct: 979 RIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTH 1037
Score = 158 bits (400), Expect = 4e-38
Identities = 98/309 (31%), Positives = 137/309 (44%), Gaps = 40/309 (12%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC C +F S H R H +KP++C +C ++F+ NL H+ H+GE P C
Sbjct: 738 YKCLECGKNFSDRSNLNTHQRIHT-GEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKC 796
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELA------- 148
C K F++ ++L H +H CSE G F + H +E A
Sbjct: 797 GECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSI 856
Query: 149 --------------GTRQHACKACKKEFETSSELKEHMKTHY------------KIRVSS 182
G + + C C + F SS L H + H SS
Sbjct: 857 SKDLNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTGEKPYECAECGKSFSKSS 916
Query: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242
T + ++ Y C CGK F + S+L H R+HTGE+P+KC ECGK F + L T
Sbjct: 917 TLANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLIT 976
Query: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302
H HTGEKP+ C C F+Q +L H QR+H+ K Y CTEC F + +
Sbjct: 977 HQRIHTGEKPYKCRECGKCFNQSSSLIIH-QRIHTGEK---PYKCTECGKDFNNSSHFSA 1032
Query: 303 HISKMHMGG 311
H + H GG
Sbjct: 1033 H-RRTHAGG 1040
Score = 154 bits (390), Expect = 6e-37
Identities = 118/421 (28%), Positives = 165/421 (39%), Gaps = 80/421 (19%)
Query: 142 EHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPH 201
+H+ + + C C K F SS H + H + Y C
Sbjct: 699 DHQGLYLAEKPYKCDTCMKSFSRSSHFIAHQRIHTGEK----------------PYKCLE 742
Query: 202 CGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAA 261
CGK F S L H RIHTGE+P+KC ECGK+F+ L TH HTGEKP+ C C +
Sbjct: 743 CGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGECWKS 802
Query: 262 FSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTET 321
F+Q NL H QR+H G C+E F S + H +NST T
Sbjct: 803 FNQSSNLLKH-QRIH---LGGNPDQCSEPGGNFAQSPSFSAHW--------RNSTEET-- 848
Query: 322 AHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQ 381
A QP S I + L P SG+ +
Sbjct: 849 -----------------------APEQPQS------ISKDLNSPGPHSTNSGEKLYECSE 879
Query: 382 LSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTD 441
+ + ++ ++G A C S S+++N Q T
Sbjct: 880 CGRSFSKSSALISHQRIHTGEKPYECA-----ECGKSFSKS-------STLANHQRTHTG 927
Query: 442 AEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHI 501
+ K + + ++ K + + R G + + C C K FR S+L+ H
Sbjct: 928 EKPYKCVDCGKCFSERSKLITHQ---------RVHTGEKPYKCLECGKFFRDRSNLITHQ 978
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHT 561
RIHT EKP+KC +C + F S+L H + HTG K +KC C K F+ S H R H
Sbjct: 979 RIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTHA 1038
Query: 562 G 562
G
Sbjct: 1039 G 1039
Score = 148 bits (374), Expect = 4e-35
Identities = 94/310 (30%), Positives = 132/310 (42%), Gaps = 29/310 (9%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F S+L H R HTGEKPYKC CG+ F L +H++ HTG K +
Sbjct: 736 KPYKCLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYK 795
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKR--HQTVPS---A 1079
C C SF + +L +H H+ P +C F + H + +T P +
Sbjct: 796 CGECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQS 855
Query: 1080 VSATGETEGGDICMEEEE--EHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEK 1137
+S + G E+ E S+ S +I+ T + +P E A +
Sbjct: 856 ISKDLNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTGE----KPYECAECGKS 911
Query: 1138 VLVQSAAEKDRISELRDKQAELQDEPK----------HANC--------CTYCPKSFKKP 1179
S + + +K + D K H C C K F+
Sbjct: 912 FSKSSTLANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDR 971
Query: 1180 SDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLK 1239
S+L+ H RIHTGEKPYKC ECGK F S+L H + HTG+K + C C F+
Sbjct: 972 SNLITHQRIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFS 1031
Query: 1240 VHMRLHTGAK 1249
H R H G K
Sbjct: 1032 AHRRTHAGGK 1041
Score = 124 bits (310), Expect = 1e-27
Identities = 84/304 (27%), Positives = 128/304 (42%), Gaps = 84/304 (27%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH- 532
R G + + C C K F S+L+ H RIHT EKP+KC +C+++F S L H + H
Sbjct: 758 RIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGECWKSFNQSSNLLKHQRIHL 817
Query: 533 ----------------------------------------------------TGIKAFKC 540
+G K ++C
Sbjct: 818 GGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDLNSPGPHSTNSGEKLYEC 877
Query: 541 QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASH-FKHTELR 595
C +SFS S +L H R+HTG +P+ C C K F S H++TH +K +
Sbjct: 878 SECGRSFSKSSALISHQRIHTGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCG 937
Query: 596 KMRHQRKPA----KVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFN---NN 648
K +R +V G ++P + G +FF+ N +
Sbjct: 938 KCFSERSKLITHQRVHTG-----------EKPYKCLECG--------KFFRDRSNLITHQ 978
Query: 649 FVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHT 708
++ ++PYKC C + + +S L H R HTGEKP+KC++CG+ F ++ AH RTH
Sbjct: 979 RIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTHA 1038
Query: 709 GLKS 712
G K+
Sbjct: 1039 GGKA 1042
Score = 120 bits (302), Expect = 9e-27
Identities = 82/272 (30%), Positives = 117/272 (43%), Gaps = 53/272 (19%)
Query: 413 DSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGS 472
D C ++ AQ+P S+ T+ T EQ P+ + K PG
Sbjct: 822 DQC-SEPGGNFAQSPSFSAHWRNSTEETAPEQ------PQSISKDLNS---------PGP 865
Query: 473 IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532
+G + + C C + F K S L+ H RIHT EKP++C +C ++F+ STL H +TH
Sbjct: 866 HSTNSGEKLYECSECGRSFSKSSALISHQRIHTGEKPYECAECGKSFSKSSTLANHQRTH 925
Query: 533 TGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHT 592
TG K +KC C K FS L H R+HTG +P+ C C K FR + TH
Sbjct: 926 TGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLITH-------- 977
Query: 593 ELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVN 651
+++ KP K R GK NQ S + ++
Sbjct: 978 --QRIHTGEKPYKCRECGKC-------------------------FNQ-SSSLIIHQRIH 1009
Query: 652 EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEK 683
++PYKC C + + S H H R+H G K
Sbjct: 1010 TGEKPYKCTECGKDFNNSSHFSAHRRTHAGGK 1041
Score = 119 bits (299), Expect = 2e-26
Identities = 59/150 (39%), Positives = 85/150 (56%), Gaps = 3/150 (2%)
Query: 1135 SEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKP 1194
S++ +S++E+D + +L D Q E + C C KSF + S + H RIHTGEKP
Sbjct: 681 SQEQWQESSSEED-LEKLIDHQGLYLAEKPYK--CDTCMKSFSRSSHFIAHQRIHTGEKP 737
Query: 1195 YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCP 1254
YKC ECGK+F+ +S L+ H + HTG+K + C C +FS +L H R+HTG KP+KC
Sbjct: 738 YKCLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCG 797
Query: 1255 HCELRFRTSGRRKTHMQFHYKPDPKKARKP 1284
C F S H + H +P + +P
Sbjct: 798 ECWKSFNQSSNLLKHQRIHLGGNPDQCSEP 827
Score = 118 bits (296), Expect = 5e-26
Identities = 78/252 (30%), Positives = 105/252 (41%), Gaps = 41/252 (16%)
Query: 37 HKCEICLLSFPKESQFQRHMR------------------------DHERNDKPHRCDQCP 72
+KC C SF + S +H R H RN + P
Sbjct: 794 YKCGECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQP 853
Query: 73 QTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFT 131
Q+ + + N T+SGE C C + FS+ ++L +H +H E+ C+ECG F+
Sbjct: 854 QSISKDLNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTGEKPYECAECGKSFS 913
Query: 132 LQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YK-------IR 179
S LA H H G + + C C K F S+L H + H YK R
Sbjct: 914 KSSTLANHQRTH----TGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFR 969
Query: 180 VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
S ++ I Y C CGK F + S L H RIHTGE+P+KC+ECGK FN
Sbjct: 970 DRSNLITHQRIHTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSH 1029
Query: 240 LQTHMIKHTGEK 251
H H G K
Sbjct: 1030 FSAHRRTHAGGK 1041
Score = 115 bits (287), Expect = 5e-25
Identities = 61/179 (34%), Positives = 90/179 (50%), Gaps = 23/179 (12%)
Query: 1645 APGNQPEKEG-RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKE 1703
+PG G + ++C EC R+FS ++ L+ H + +H E+ + C C K+F +++ L
Sbjct: 862 SPGPHSTNSGEKLYECSECGRSFSKSSALISHQR-IHTGEKPYECAECGKSFSKSSTLAN 920
Query: 1704 HMQTH---------QAGPSLSSQKPRV-----------FKCDTCEKAFAKPSQLERHSRI 1743
H +TH G S + + +KC C K F S L H RI
Sbjct: 921 HQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLITHQRI 980
Query: 1744 HTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
HTGE+P+ C C K FNQ S+L +H + HTGE+PYKC C F S+ H +R H+
Sbjct: 981 HTGEKPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAH-RRTHA 1038
Score = 103 bits (258), Expect = 1e-21
Identities = 57/193 (29%), Positives = 98/193 (50%), Gaps = 47/193 (24%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAG--- 1711
+ ++CLEC ++FS + L+ H + +H E+ + C C K+F ++++L +H + H G
Sbjct: 764 KPYKCLECGKSFSDHSNLITHQR-IHTGEKPYKCGECWKSFNQSSNLLKHQRIHLGGNPD 822
Query: 1712 ------------PSLSS-----------QKP-------------------RVFKCDTCEK 1729
PS S+ ++P ++++C C +
Sbjct: 823 QCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDLNSPGPHSTNSGEKLYECSECGR 882
Query: 1730 AFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQ 1789
+F+K S L H RIHTGE+P+ C C K+F++ S L H + HTGE+PYKC C F++
Sbjct: 883 SFSKSSALISHQRIHTGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCGKCFSE 942
Query: 1790 KSNMKLHMKRAHS 1802
+S + H +R H+
Sbjct: 943 RSKLITH-QRVHT 954
Score = 100 bits (250), Expect = 1e-20
Identities = 53/137 (38%), Positives = 73/137 (53%), Gaps = 17/137 (12%)
Query: 1683 ERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSR 1742
E+ + C C K+F R++H H + H + +KP +KC C K F+ S L H R
Sbjct: 707 EKPYKCDTCMKSFSRSSHFIAHQRIH------TGEKP--YKCLECGKNFSDRSNLNTHQR 758
Query: 1743 IHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
IHTGE+P+ C C K+F+ S L H + HTGE+PYKC C F Q SN+ H +R H
Sbjct: 759 IHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGECWKSFNQSSNLLKH-QRIH- 816
Query: 1803 YAGALQESAGHPEQDGE 1819
G+P+Q E
Sbjct: 817 -------LGGNPDQCSE 826
Score = 98.6 bits (244), Expect = 5e-20
Identities = 62/201 (30%), Positives = 84/201 (41%), Gaps = 22/201 (10%)
Query: 22 LNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNL 81
LN+ + ++C C SF K S H R H +KP+ C +C ++F+ L
Sbjct: 860 LNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIH-TGEKPYECAECGKSFSKSSTL 918
Query: 82 TLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHM 140
H+ TH+GE P C C K FS + L H +H E+ C ECG F +S L H
Sbjct: 919 ANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLITHQ 978
Query: 141 EEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCP 200
H G + + C+ C K F SS L H + H + Y C
Sbjct: 979 RIH----TGEKPYKCRECGKCFNQSSSLIIHQRIHTGEK----------------PYKCT 1018
Query: 201 HCGKTFQKPSQLTRHIRIHTG 221
CGK F S + H R H G
Sbjct: 1019 ECGKDFNNSSHFSAHRRTHAG 1039
Score = 89.7 bits (221), Expect = 2e-17
Identities = 53/176 (30%), Positives = 84/176 (47%), Gaps = 18/176 (10%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C C ++FS ++ + H + +H E+ + C C K F ++L H + H
Sbjct: 708 KPYKCDTCMKSFSRSSHFIAHQR-IHTGEKPYKCLECGKNFSDRSNLNTHQRIH------ 760
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C K+F+ S L H RIHTGE+P+ C C K+FNQ S L H + H G
Sbjct: 761 TGEKP--YKCLECGKSFSDHSNLITHQRIHTGEKPYKCGECWKSFNQSSNLLKHQRIHLG 818
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRA---------HSYAGALQESAGHPEQDGEEL 1821
P +C+ F Q + H + + S + L H GE+L
Sbjct: 819 GNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDLNSPGPHSTNSGEKL 874
Score = 89.4 bits (220), Expect = 3e-17
Identities = 38/83 (45%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 1716 SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE 1775
++KP +KCDTC K+F++ S H RIHTGE+P+ C C K F+ +S L H + HTGE
Sbjct: 706 AEKP--YKCDTCMKSFSRSSHFIAHQRIHTGEKPYKCLECGKNFSDRSNLNTHQRIHTGE 763
Query: 1776 RPYKCAYCVMGFTQKSNMKLHMK 1798
+PYKC C F+ SN+ H +
Sbjct: 764 KPYKCLECGKSFSDHSNLITHQR 786
Score = 86.7 bits (213), Expect = 2e-16
Identities = 46/134 (34%), Positives = 69/134 (51%), Gaps = 9/134 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S LA + + ++C++C + FS + L+ H + VH E+ + C C K F+ ++
Sbjct: 915 SSTLANHQRTHTGEKPYKCVDCGKCFSERSKLITHQR-VHTGEKPYKCLECGKFFRDRSN 973
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L H + H + +KP +KC C K F + S L H RIHTGE+P+ CT C K FN
Sbjct: 974 LITHQRIH------TGEKP--YKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFN 1025
Query: 1761 QKSALQVHMKKHTG 1774
S H + H G
Sbjct: 1026 NSSHFSAHRRTHAG 1039
Score = 84.3 bits (207), Expect = 1e-15
Identities = 42/124 (33%), Positives = 59/124 (47%)
Query: 650 VNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTG 709
++ ++PYKC C + + +L H R HTGEKP+KC +CG+ F L H R HTG
Sbjct: 731 IHTGEKPYKCLECGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTG 790
Query: 710 LKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQ 769
K +KC C +F +L +H IH P C F S + H + E A
Sbjct: 791 EKPYKCGECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAP 850
Query: 770 QLQQ 773
+ Q
Sbjct: 851 EQPQ 854
Score = 65.1 bits (157), Expect = 6e-10
Identities = 29/58 (50%), Positives = 36/58 (62%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKA 1022
+ Y+C C K F +SS L H R HTGEKPYKC CG+ F +S +H +TH G KA
Sbjct: 985 KPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTHAGGKA 1042
Score = 60.5 bits (145), Expect = 2e-08
Identities = 22/59 (37%), Positives = 35/59 (59%)
Query: 1740 HSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
H ++ E+P+ C C K+F++ S H + HTGE+PYKC C F+ +SN+ H +
Sbjct: 700 HQGLYLAEKPYKCDTCMKSFSRSSHFIAHQRIHTGEKPYKCLECGKNFSDRSNLNTHQR 758
Score = 43.5 bits (101), Expect = 0.002
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAG 1711
+ ++C EC + F+ ++ L+ H + +H E+ + C C K F ++H H +TH G
Sbjct: 985 KPYKCRECGKCFNQSSSLIIHQR-IHTGEKPYKCTECGKDFNNSSHFSAHRRTHAGG 1040
>gi|113680890 zinc finger protein 90 [Homo sapiens]
Length = 636
Score = 210 bits (534), Expect = 1e-53
Identities = 120/345 (34%), Positives = 167/345 (48%), Gaps = 34/345 (9%)
Query: 958 DNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTH 1017
+N + Y+C C K F++SS L QH R HTGEKPY+C LCGR F L HE TH
Sbjct: 301 ENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTH 360
Query: 1018 TGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVP 1077
+G K F C C +F+ SL +H TH KP++C C F + KHM+ H+
Sbjct: 361 SGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGK 420
Query: 1078 SAVS---------ATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRP 1128
S +T T+ E + H N + + FT+ + +I
Sbjct: 421 PYQSSNYSIDFKHSTSLTQDESTLTEVKSYHC--NDCGEDFSHITDFTDHQ-----RIHT 473
Query: 1129 QESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRI 1188
E+ E+ Q A IS +K + C C K+FK+ + + H RI
Sbjct: 474 AENPYDCEQAFSQQA-----ISHPGEKPYQ----------CNVCGKAFKRSTSFIEHHRI 518
Query: 1189 HTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGA 1248
HTGEKPY+C+ECG++F+ +S+L H +THTG+K + C C AFS SL H R HTG
Sbjct: 519 HTGEKPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGE 578
Query: 1249 KPFKCPHCELRFRTSGRRKTHMQFHYKPDP---KKARKPMTRSSS 1290
KP++C C FR H + H P K+ K +RSS+
Sbjct: 579 KPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSA 623
Score = 196 bits (497), Expect = 2e-49
Identities = 143/499 (28%), Positives = 218/499 (43%), Gaps = 76/499 (15%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLIC 123
KP++CD+C + F +LT H+ TH GE N + K H HE C
Sbjct: 209 KPYKCDKCRKAFIHRSSLTKHEKTHKGEG---AFPNGTDQGIYPGKKH---HE------C 256
Query: 124 SECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSST 183
++CG F ++QL H H G + C C K F SS L +H H +
Sbjct: 257 TDCGKTFLWKTQLTEHQRIH----TGEKPFECNVCGKAFRHSSSLGQHENAH-----TGE 307
Query: 184 RSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTH 243
+ Y C CGK FQ+ S L +H RIHTGE+P++C+ CG++F +L H
Sbjct: 308 KPY-----------QCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQH 356
Query: 244 MIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
+ H+GEKP C C AFS+ +L H +R H+ K + C+ C F SL H
Sbjct: 357 EVTHSGEKPFQCKECGKAFSRCSSLVQH-ERTHTGEK---PFECSICGRAFGQSPSLYKH 412
Query: 304 ISKMHMGGP-QNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLL 362
+ G P Q+S S + H + L Q E+ T S + D +
Sbjct: 413 MRIHKRGKPYQSSNYSIDFKH--------STSLTQDESTLTEVKSYHCNDCGED-FSHIT 463
Query: 363 ELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAP 422
+ ++ + + ++P +Q QQA+ +HP + +
Sbjct: 464 DFTDHQRIHTAENPYDCEQA---------FSQQAI-----------SHPGEKPYQCNVCG 503
Query: 423 HAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWH 482
A S + + + E P + ++ + ++ S L R G + +
Sbjct: 504 KAFKRSTSFIEHHRI--------HTGEKPYECNECGEAFSRRSS--LTQHERTHTGEKPY 553
Query: 483 VCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQY 542
C C K F + S L++H R HT EKP++C +C RAF K+ L H + HTG K + C+
Sbjct: 554 ECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKE 613
Query: 543 CMKSFSTSGSLKVHIRLHT 561
C K+FS S +L H R+HT
Sbjct: 614 CGKNFSRSSALTKHQRIHT 632
Score = 191 bits (486), Expect = 4e-48
Identities = 138/443 (31%), Positives = 201/443 (45%), Gaps = 49/443 (11%)
Query: 147 LAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTF 206
LA + + C C+K F S L +H KTH K + ++ I + C CGKTF
Sbjct: 205 LAKKKPYKCDKCRKAFIHRSSLTKHEKTH-KGEGAFPNGTDQGIYPGKKHHECTDCGKTF 263
Query: 207 QKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKG 266
+QLT H RIHTGE+PF+C+ CGKAF +L H HTGEKP+ C+ C AF +
Sbjct: 264 LWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAFQRSS 323
Query: 267 NLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLT 326
+L H QR+H+ K Y C C F+ SL H H G A
Sbjct: 324 SLVQH-QRIHTGEK---PYRCNLCGRSFRHGTSLTQH-EVTHSGEKPFQCKECGKAFSRC 378
Query: 327 ATLFQTLPLQQTEAQATSASSQPSSQAV-SDVIQQLLELSEPAPVESGQSPQPGQQLSIT 385
++L Q + T +P ++ Q L + + P SI
Sbjct: 379 SSLVQ--------HERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSID 430
Query: 386 VGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQE 445
+ + Q + S L+ + + H ND D S + TD TD ++
Sbjct: 431 FKHSTSLTQ---DESTLTEV-KSYHCNDC-----------GEDFSHI----TDFTDHQRI 471
Query: 446 KEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 505
E+P ++ F +I G + + C C K F++ + + H RIHT
Sbjct: 472 HTAENPYDCEQ----------AFSQQAI-SHPGEKPYQCNVCGKAFKRSTSFIEHHRIHT 520
Query: 506 HEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRP 565
EKP++C +C AF+ +S+LT H +THTG K ++C C K+FS S SL H R HTG +P
Sbjct: 521 GEKPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKP 580
Query: 566 FACPHCDKKFRTSGHRKTHIASH 588
+ C C + FR +KT++ H
Sbjct: 581 YECNECGRAFR----KKTNLHDH 599
Score = 181 bits (458), Expect = 8e-45
Identities = 104/308 (33%), Positives = 153/308 (49%), Gaps = 26/308 (8%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C C K F++ S LV+H RIHT EKP++C C R+F ++LT H TH+G K
Sbjct: 306 GEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKP 365
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKM 597
F+C+ C K+FS SL H R HTG +PF C C + F S S +KH + K
Sbjct: 366 FQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQS-------PSLYKHMRIHKR 418
Query: 598 RHQRKPAKVRVG---KTNIPVPDIPLQEP------------ILITDLGLIQPI--PKNQF 640
+ + + T++ + L E ITD Q I +N +
Sbjct: 419 GKPYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPY 478
Query: 641 --FQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAG 698
Q++ + ++PY+C C +A+K+S +H R HTGEKP++C++CG F
Sbjct: 479 DCEQAFSQQAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRS 538
Query: 699 VLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKK 758
L H RTHTG K ++C+ C AF+ SL +H H +PY C C + F+ N
Sbjct: 539 SLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNLHD 598
Query: 759 HMKTHRYE 766
H + H E
Sbjct: 599 HQRIHTGE 606
Score = 170 bits (431), Expect = 1e-41
Identities = 104/324 (32%), Positives = 156/324 (48%), Gaps = 43/324 (13%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
++C +C +F + S +H R H +KP+RC+ C ++F +LT H+ THSGE P C
Sbjct: 310 YQCSLCGKAFQRSSSLVQHQRIHT-GEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQC 368
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQ---------- 145
C K FSR +SL H H E+ CS CG F L HM H++
Sbjct: 369 KECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYS 428
Query: 146 --------------ELAGTRQHACKACKKEFETSSELKEHMKTH-YKIRVSSTRSYNRN- 189
L + + C C ++F ++ +H + H + +++++
Sbjct: 429 IDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQA 488
Query: 190 IDRSG-FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHT 248
I G Y C CGK F++ + H RIHTGE+P++C+ECG+AF+++ +L H HT
Sbjct: 489 ISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTHT 548
Query: 249 GEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMH 308
GEKP+ C C AFSQ +L H +R H+ K Y C EC F+ +L+ H ++H
Sbjct: 549 GEKPYECIDCGKAFSQSSSLIQH-ERTHTGEK---PYECNECGRAFRKKTNLHDH-QRIH 603
Query: 309 MG---------GPQNSTSSTETAH 323
G G S SS T H
Sbjct: 604 TGEKPYSCKECGKNFSRSSALTKH 627
Score = 158 bits (400), Expect = 4e-38
Identities = 92/302 (30%), Positives = 139/302 (46%), Gaps = 12/302 (3%)
Query: 474 REENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHT 533
R G + + C C + FR + L +H H+ EKPF+C +C +AF+ S+L H +THT
Sbjct: 330 RIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHT 389
Query: 534 GIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPH--CDKKFRTSGHRKTHIASHFKH 591
G K F+C C ++F S SL H+R+H +P+ + D K TS + + K
Sbjct: 390 GEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSIDFKHSTSLTQDESTLTEVKS 449
Query: 592 TELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPK-------NQFFQ-- 642
I + P + + P K + F+
Sbjct: 450 YHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAISHPGEKPYQCNVCGKAFKRS 509
Query: 643 -SYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
S+ ++ ++ ++PY+C C A+ + L QH R+HTGEKP++C CG+ F + L
Sbjct: 510 TSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLI 569
Query: 702 AHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMK 761
H RTHTG K ++C C AF +L H IH +PY C C K F S KH +
Sbjct: 570 QHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQR 629
Query: 762 TH 763
H
Sbjct: 630 IH 631
Score = 155 bits (393), Expect = 3e-37
Identities = 124/468 (26%), Positives = 181/468 (38%), Gaps = 76/468 (16%)
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPF---------------KCSQC 690
N N + +PYKC C +A+ L +H ++H GE F +C+ C
Sbjct: 200 NENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDC 259
Query: 691 GRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTF 750
G+ F+ L H R HTG K F+C +C AF SL +H H +PY C C K F
Sbjct: 260 GKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAF 319
Query: 751 KTSLNCKKHM------KTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDE 804
+ S + +H K +R L + +H + TQ +V ++
Sbjct: 320 QRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSL---------------TQHEVTHSGEK 364
Query: 805 LPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDP-LRGHVD 863
Q E A +V E G++ P E G Q P L H+
Sbjct: 365 PFQCKECGKAFSRC------SSLVQHERTHTGEK----PFECSICGRAFGQSPSLYKHMR 414
Query: 864 QFEEQSPAQQSFEPAGLPQGFTVTD---------TYHQQP---QFPPVQQLQDSSTLESQ 911
+ P Q S ++T +YH F + D + +
Sbjct: 415 IHKRGKPYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTA 474
Query: 912 ALSTSFHQQSLLQAPSSDG-----MNVTTRLIQESSQEELDLQAQGSQFLEDNEDQS-RR 965
Q QA S G NV + + S+ F+E + + +
Sbjct: 475 ENPYDCEQAFSQQAISHPGEKPYQCNVCGKAFKRSTS-----------FIEHHRIHTGEK 523
Query: 966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025
Y C+ C + F + S L QH R+HTGEKPY+C CG+ F S L HE+THTG K + C
Sbjct: 524 PYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYEC 583
Query: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRH 1073
+ C +F +L H H KPY C C + F + KH + H
Sbjct: 584 NECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQRIH 631
Score = 142 bits (357), Expect = 4e-33
Identities = 96/336 (28%), Positives = 141/336 (41%), Gaps = 62/336 (18%)
Query: 31 YQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSG 90
Y H+C C +F ++Q H R H +KP C+ C + F +L H+ H+G
Sbjct: 248 YPGKKHHECTDCGKTFLWKTQLTEHQRIHT-GEKPFECNVCGKAFRHSSSLGQHENAHTG 306
Query: 91 EDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVH---------- 139
E P C +C K F R +SL H +H E+ C+ CG F + L H
Sbjct: 307 EKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPF 366
Query: 140 --------------MEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRS 185
+ +H + G + C C + F S L +HM+ H + + + +
Sbjct: 367 QCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSN 426
Query: 186 YNRNI--------DRSGFT----YSCPHCGKTFQKPSQLTRHIRIHT------------- 220
Y+ + D S T Y C CG+ F + T H RIHT
Sbjct: 427 YSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQ 486
Query: 221 ------GERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQR 274
GE+P++C+ CGKAF + + H HTGEKP+ C C AFS++ +L H +R
Sbjct: 487 QAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQH-ER 545
Query: 275 VHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG 310
H+ K Y C +C F SL H + H G
Sbjct: 546 THTGEK---PYECIDCGKAFSQSSSLIQH-ERTHTG 577
Score = 139 bits (351), Expect = 2e-32
Identities = 146/607 (24%), Positives = 219/607 (36%), Gaps = 103/607 (16%)
Query: 120 NLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIR 179
+L+ + D + + SQL E ++ L + +K+ T E E K R
Sbjct: 111 DLLHATLEDSWDVSSQLDRQQENWKRHLGSEA-----STQKKIITPQENFEQNKFGENSR 165
Query: 180 VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGA 239
+++ NI C G + L I ++P+KC +C KAF + +
Sbjct: 166 LNTNLVTQLNIPARIRPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSS 225
Query: 240 LQTHMIKHTGE---------------KPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT 284
L H H GE K H C C F K L H QR+H+ K
Sbjct: 226 LTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDCGKTFLWKTQLTEH-QRIHTGEK---P 281
Query: 285 YNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATS 344
+ C C F+ SL H H G S A +++L Q + E
Sbjct: 282 FECNVCGKAFRHSSSLGQH-ENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRC 340
Query: 345 ASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSS 404
S + + + Q + S P Q + G+ S + Q E S
Sbjct: 341 NLCGRSFRHGTSLTQHEVTHSGEKPF---QCKECGKAFSRCSSLVQHERTHTGEKPFECS 397
Query: 405 IPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKK 464
I A K H + S SN D + + ES
Sbjct: 398 ICGRAFGQSPSLYKHMRIHKRGKPYQS-SNYSIDFKHSTSLTQDES-------------- 442
Query: 465 KSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKST 524
++ E V+ + C C ++F +D H RIHT E P+ C Q F A+
Sbjct: 443 -------TLTE---VKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAI--- 489
Query: 525 LTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTH 584
+H G K ++C C K+F S S H R+HTG +P+ C C + F R++
Sbjct: 490 ------SHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFS----RRSS 539
Query: 585 IASHFK-HTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQS 643
+ H + HT ++P D G F QS
Sbjct: 540 LTQHERTHTG---------------------------EKPYECIDCG-------KAFSQS 565
Query: 644 --YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLK 701
+ + ++PY+C C RA++K +L H R HTGEKP+ C +CG+ F + L
Sbjct: 566 SSLIQHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALT 625
Query: 702 AHIRTHT 708
H R HT
Sbjct: 626 KHQRIHT 632
Score = 132 bits (333), Expect = 2e-30
Identities = 90/309 (29%), Positives = 127/309 (41%), Gaps = 59/309 (19%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ YRC+ C + F+ + L QH +H+GEKP++CK CG+ F L HE+THTG K F
Sbjct: 336 KPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFE 395
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYK----------------------------CPFC 1056
CS+C +F + SL +HM H KPY+ C C
Sbjct: 396 CSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDC 455
Query: 1057 EEGFRTTVHCKKHMKRHQT-----VPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPE 1111
E F H + H A S + G E+ N K+
Sbjct: 456 GEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAISHPG-------EKPYQCNVCGKAFKR 508
Query: 1112 VITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAE------------- 1158
+F E + +P E E +S+ + + +K E
Sbjct: 509 STSFIEHHRIHTGE-KPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSS 567
Query: 1159 -LQDEPKHANC----CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCH 1213
+Q E H C C ++F+K ++L H RIHTGEKPY C ECGK+F+ S L H
Sbjct: 568 LIQHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKH 627
Query: 1214 VKTHTGQKL 1222
+ HT KL
Sbjct: 628 QRIHTRNKL 636
Score = 125 bits (313), Expect = 5e-28
Identities = 107/419 (25%), Positives = 166/419 (39%), Gaps = 61/419 (14%)
Query: 410 HPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKE----------- 458
+P+ + + H Q DVS VS+ D A E + +LD+++
Sbjct: 84 YPDWKTRPEVKSSHLQQ-DVSEVSHCTHDLLHATLEDSWDVSSQLDRQQENWKRHLGSEA 142
Query: 459 ---KKMIKKKSPFLPGSIREENGVRWHV--------------CPYCAKEFRKPSDLVRHI 501
KK+I + F E + + ++ C +DL+
Sbjct: 143 STQKKIITPQENFEQNKFGENSRLNTNLVTQLNIPARIRPSECETLGSNLGHNADLLNEN 202
Query: 502 RIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAF---------------KCQYCMKS 546
I +KP+KC +C +AF +S+LT H KTH G AF +C C K+
Sbjct: 203 NILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDCGKT 262
Query: 547 FSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSG----HRKTHIASHFKHTELRKMRHQRK 602
F L H R+HTG +PF C C K FR S H H L QR
Sbjct: 263 FLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAFQRS 322
Query: 603 PAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYC 662
+ V+ + + ++P G + S + + ++P++C C
Sbjct: 323 SSLVQHQRIHTG------EKPYRCNLCGR-----SFRHGTSLTQHEVTHSGEKPFQCKEC 371
Query: 663 HRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAF 722
+A+ + L QH R+HTGEKPF+CS CGR F + L H+R H K ++ + F
Sbjct: 372 GKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSIDF 431
Query: 723 TTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQ--HQQAAS 779
SL + +++ Y C C + F + H + H E +Q QQA S
Sbjct: 432 KHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAIS 490
Score = 121 bits (304), Expect = 5e-27
Identities = 73/221 (33%), Positives = 100/221 (45%), Gaps = 32/221 (14%)
Query: 32 QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGE 91
+V ++H C C F + F H R H + P+ C+Q + +H GE
Sbjct: 446 EVKSYH-CNDCGEDFSHITDFTDHQRIHTA-ENPYDCEQA---------FSQQAISHPGE 494
Query: 92 DP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGT 150
P C VC K F R S H +H E+ C+ECG+ F+ +S L H H G
Sbjct: 495 KPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTH----TGE 550
Query: 151 RQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPS 210
+ + C C K F SS L +H +TH + Y C CG+ F+K +
Sbjct: 551 KPYECIDCGKAFSQSSSLIQHERTHTGEK----------------PYECNECGRAFRKKT 594
Query: 211 QLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEK 251
L H RIHTGE+P+ C ECGK F++ AL H HT K
Sbjct: 595 NLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQRIHTRNK 635
Score = 118 bits (295), Expect = 6e-26
Identities = 76/259 (29%), Positives = 111/259 (42%), Gaps = 17/259 (6%)
Query: 1020 VKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSA 1079
++ C ++ N L KPYKC C + F KH K H+
Sbjct: 180 IRPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHK----- 234
Query: 1080 VSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVL 1139
G D + ++H + K+ TE + + +P E +
Sbjct: 235 -GEGAFPNGTDQGIYPGKKHHECTDCGKTFLWKTQLTEHQRIHTGE-KPFECNVCGKAFR 292
Query: 1140 VQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDE 1199
S+ + + +K + C+ C K+F++ S LV+H RIHTGEKPY+C+
Sbjct: 293 HSSSLGQHENAHTGEKPYQ----------CSLCGKAFQRSSSLVQHQRIHTGEKPYRCNL 342
Query: 1200 CGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELR 1259
CG+SF ++L H TH+G+K F C C AFS SL H R HTG KPF+C C
Sbjct: 343 CGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRA 402
Query: 1260 FRTSGRRKTHMQFHYKPDP 1278
F S HM+ H + P
Sbjct: 403 FGQSPSLYKHMRIHKRGKP 421
Score = 111 bits (278), Expect = 6e-24
Identities = 55/138 (39%), Positives = 83/138 (60%), Gaps = 15/138 (10%)
Query: 1661 ECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPR 1720
+C++AFS A+ H E+ + C VC KAFKR+T EH + H + +KP
Sbjct: 479 DCEQAFSQQAIS-------HPGEKPYQCNVCGKAFKRSTSFIEHHRIH------TGEKP- 524
Query: 1721 VFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKC 1780
++C+ C +AF++ S L +H R HTGE+P+ C C KAF+Q S+L H + HTGE+PY+C
Sbjct: 525 -YECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYEC 583
Query: 1781 AYCVMGFTQKSNMKLHMK 1798
C F +K+N+ H +
Sbjct: 584 NECGRAFRKKTNLHDHQR 601
Score = 109 bits (273), Expect = 2e-23
Identities = 54/153 (35%), Positives = 85/153 (55%), Gaps = 15/153 (9%)
Query: 1646 PGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHM 1705
PG +P +QC C +AF + + H + +H E+ + C C +AF R + L +H
Sbjct: 492 PGEKP------YQCNVCGKAFKRSTSFIEHHR-IHTGEKPYECNECGEAFSRRSSLTQHE 544
Query: 1706 QTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSAL 1765
+TH + +KP ++C C KAF++ S L +H R HTGE+P+ C C +AF +K+ L
Sbjct: 545 RTH------TGEKP--YECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNL 596
Query: 1766 QVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
H + HTGE+PY C C F++ S + H +
Sbjct: 597 HDHQRIHTGEKPYSCKECGKNFSRSSALTKHQR 629
Score = 107 bits (266), Expect = 1e-22
Identities = 51/146 (34%), Positives = 83/146 (56%), Gaps = 10/146 (6%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSS 1716
H+C +C + F L H + +H E+ C VC KAF+ ++ L +H H +
Sbjct: 254 HECTDCGKTFLWKTQLTEHQR-IHTGEKPFECNVCGKAFRHSSSLGQHENAH------TG 306
Query: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGER 1776
+KP ++C C KAF + S L +H RIHTGE+P+ C LC ++F ++L H H+GE+
Sbjct: 307 EKP--YQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEK 364
Query: 1777 PYKCAYCVMGFTQKSNMKLHMKRAHS 1802
P++C C F++ S++ H +R H+
Sbjct: 365 PFQCKECGKAFSRCSSLVQH-ERTHT 389
Score = 105 bits (261), Expect = 5e-22
Identities = 52/125 (41%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Query: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVC 1228
CT C K+F + L H RIHTGEKP++C+ CGK+F S+L H HTG+K + C +C
Sbjct: 256 CTDCGKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLC 315
Query: 1229 SNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDP---KKARKPM 1285
AF SL H R+HTG KP++C C FR H H P K+ K
Sbjct: 316 GKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAF 375
Query: 1286 TRSSS 1290
+R SS
Sbjct: 376 SRCSS 380
Score = 103 bits (256), Expect = 2e-21
Identities = 58/181 (32%), Positives = 88/181 (48%), Gaps = 23/181 (12%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGR------- 1682
CE + + G + +L N + + ++C +C +AF + L H K G
Sbjct: 185 CETLGSNL-GHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGT 243
Query: 1683 -------ERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPS 1735
++ H C C K F T L EH + H + +KP F+C+ C KAF S
Sbjct: 244 DQGIYPGKKHHECTDCGKTFLWKTQLTEHQRIH------TGEKP--FECNVCGKAFRHSS 295
Query: 1736 QLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKL 1795
L +H HTGE+P+ C+LC KAF + S+L H + HTGE+PY+C C F +++
Sbjct: 296 SLGQHENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQ 355
Query: 1796 H 1796
H
Sbjct: 356 H 356
Score = 102 bits (255), Expect = 3e-21
Identities = 52/153 (33%), Positives = 86/153 (56%), Gaps = 10/153 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C C +AF ++ L H + H E+ + C +C KAF+R++ L +H + H + +
Sbjct: 283 ECNVCGKAFRHSSSLGQH-ENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIH------TGE 335
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP ++C+ C ++F + L +H H+GE+PF C C KAF++ S+L H + HTGE+P
Sbjct: 336 KP--YRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKP 393
Query: 1778 YKCAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810
++C+ C F Q ++ HM R H Q S
Sbjct: 394 FECSICGRAFGQSPSLYKHM-RIHKRGKPYQSS 425
Score = 102 bits (254), Expect = 3e-21
Identities = 106/499 (21%), Positives = 178/499 (35%), Gaps = 111/499 (22%)
Query: 892 QQPQFPPVQQLQD--SSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLI--QESSQEELD 947
Q+P +P + + SS L+ S LL A D +V+++L QE+ + L
Sbjct: 80 QRPFYPDWKTRPEVKSSHLQQDVSEVSHCTHDLLHATLEDSWDVSSQLDRQQENWKRHLG 139
Query: 948 LQAQGSQFL---EDNEDQSR---------------------RSYRCDYCNKGFKKSSHLK 983
+A + + ++N +Q++ R C+ ++ L
Sbjct: 140 SEASTQKKIITPQENFEQNKFGENSRLNTNLVTQLNIPARIRPSECETLGSNLGHNADLL 199
Query: 984 QHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF---------------SCSVC 1028
+KPYKC C + F+ L HEKTH G AF C+ C
Sbjct: 200 NENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDC 259
Query: 1029 NASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATGET- 1086
+F LT H H KP++C C + FR + +H H P S G+
Sbjct: 260 GKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAF 319
Query: 1087 EGGDICMEEEEEHSDR-----NASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQ 1141
+ ++ + H+ N +S + T+ E + +P + +
Sbjct: 320 QRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGE-KPFQCKECGKAFSRC 378
Query: 1142 SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYK----- 1196
S+ + + +K E C+ C ++F + L +H+RIH KPY+
Sbjct: 379 SSLVQHERTHTGEKPFE----------CSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYS 428
Query: 1197 -----------------------CDECGKSFTVKSTLDCHVKTHTGQKLFSC-------- 1225
C++CG+ F+ + H + HT + + C
Sbjct: 429 IDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQA 488
Query: 1226 -----------HVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
+VC AF S H R+HTG KP++C C F H + H
Sbjct: 489 ISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTHT 548
Query: 1275 KPDPKK---ARKPMTRSSS 1290
P + K ++SSS
Sbjct: 549 GEKPYECIDCGKAFSQSSS 567
Score = 101 bits (251), Expect = 8e-21
Identities = 48/139 (34%), Positives = 81/139 (58%), Gaps = 9/139 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ +QC C +AF ++ L+ H + +H E+ + C +C ++F+ T L +H TH
Sbjct: 308 KPYQCSLCGKAFQRSSSLVQHQR-IHTGEKPYRCNLCGRSFRHGTSLTQHEVTH------ 360
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
S +KP F+C C KAF++ S L +H R HTGE+PF C++C +AF Q +L HM+ H
Sbjct: 361 SGEKP--FQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKR 418
Query: 1775 ERPYKCAYCVMGFTQKSNM 1793
+PY+ + + F +++
Sbjct: 419 GKPYQSSNYSIDFKHSTSL 437
Score = 96.3 bits (238), Expect = 2e-19
Identities = 47/131 (35%), Positives = 72/131 (54%), Gaps = 7/131 (5%)
Query: 1675 HSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQ---AGPSLSSQK----PRVFKCDTC 1727
+ + +++ + C CRKAF + L +H +TH+ A P+ + Q + +C C
Sbjct: 200 NENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDC 259
Query: 1728 EKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGF 1787
K F +QL H RIHTGE+PF C +C KAF S+L H HTGE+PY+C+ C F
Sbjct: 260 GKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAF 319
Query: 1788 TQKSNMKLHMK 1798
+ S++ H +
Sbjct: 320 QRSSSLVQHQR 330
Score = 91.3 bits (225), Expect = 8e-18
Identities = 51/184 (27%), Positives = 85/184 (46%), Gaps = 41/184 (22%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
QC EC +AFS + L+ H + H E+ C +C +AF ++ L +HM+ H+ G S
Sbjct: 367 QCKECGKAFSRCSSLVQHER-THTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSS 425
Query: 1718 KPRV--------------------FKCDTCEKAFAKPSQLERHSRIHT------------ 1745
+ + C+ C + F+ + H RIHT
Sbjct: 426 NYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFS 485
Query: 1746 -------GERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK 1798
GE+P+ C +C KAF + ++ H + HTGE+PY+C C F+++S++ H +
Sbjct: 486 QQAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQH-E 544
Query: 1799 RAHS 1802
R H+
Sbjct: 545 RTHT 548
Score = 89.7 bits (221), Expect = 2e-17
Identities = 45/119 (37%), Positives = 69/119 (57%), Gaps = 9/119 (7%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC AFS + L H + H E+ + C C KAF +++ L +H +TH
Sbjct: 523 KPYECNECGEAFSRRSSLTQHER-THTGEKPYECIDCGKAFSQSSSLIQHERTH------ 575
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHT 1773
+ +KP ++C+ C +AF K + L H RIHTGE+P+ C C K F++ SAL H + HT
Sbjct: 576 TGEKP--YECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQRIHT 632
Score = 39.3 bits (90), Expect = 0.036
Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1720 RVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGE---- 1775
R +C+T + L + I ++P+ C C KAF +S+L H K H GE
Sbjct: 181 RPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFP 240
Query: 1776 -----------RPYKCAYCVMGFTQKSNMKLHMK 1798
+ ++C C F K+ + H +
Sbjct: 241 NGTDQGIYPGKKHHECTDCGKTFLWKTQLTEHQR 274
>gi|169790765 zinc finger protein 85 [Homo sapiens]
Length = 595
Score = 210 bits (534), Expect = 1e-53
Identities = 147/513 (28%), Positives = 214/513 (41%), Gaps = 80/513 (15%)
Query: 64 KPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLI 122
K +CD+ + + N H+ H+ + P C C K F ++ L H +H +
Sbjct: 144 KIFQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYK 203
Query: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YK 177
C ECG F S L H H G + + C+ C K F SS L +H K H YK
Sbjct: 204 CEECGKAFNWSSTLTKHKRIH----TGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYK 259
Query: 178 IRVS-------STRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSEC 230
ST + ++ I Y C CGK F + S LT H +IHTGE+P+KC EC
Sbjct: 260 CEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEEC 319
Query: 231 GKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTEC 290
GKAF Q L TH I HTGEKP+ C C AF+Q +L +H + +H+ K Y C +C
Sbjct: 320 GKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTH-EVIHTGEK---PYKCEKC 375
Query: 291 SCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQP- 349
F L TH +H G A ++TL T+ + +P
Sbjct: 376 GKAFNHFSHLTTH-KIIHTGEKPYKCKECGKAFKHSSTL--------TKHKIIHTGEKPY 426
Query: 350 SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAA 409
+ Q +L+E + +G+ P
Sbjct: 427 KCKECEKAFNQSSKLTEHKKIHTGEKP--------------------------------- 453
Query: 410 HPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFL 469
+ + C N+ ++ T ++ +E P K ++ K + +
Sbjct: 454 YECEKC--------------GKAFNQSSNLTRHKKSHTEEKPYKCEECGKGFKWPSTLTI 499
Query: 470 PGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHI 529
I G + + C C K F + S L +H +IHT EKP+ C +C +AF S LT H
Sbjct: 500 HKII--HTGEKPYKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSSNLTKHK 557
Query: 530 KTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTG 562
+ HTG K +KC+ C K+F S L H +HTG
Sbjct: 558 RIHTGEKPYKCEECDKAFKWSSVLTKHKIIHTG 590
Score = 201 bits (510), Expect = 7e-51
Identities = 119/309 (38%), Positives = 150/309 (48%), Gaps = 32/309 (10%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K FK+SS+L H HTGEKPYKCK CG+ F S L +HE HTG K +
Sbjct: 312 KPYKCEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYK 371
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F LT H H KPYKC C + F+ + KH H TG
Sbjct: 372 CEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIH---------TG 422
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAA 1144
E C E E+ N S K TE + KI E EK A
Sbjct: 423 EKPYK--CKECEKAF---NQSSK-------LTEHK-----KIHTGEKPYECEKC---GKA 462
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ R K++ +++P C C K FK PS L H IHTGEKPYKC+ECGK+F
Sbjct: 463 FNQSSNLTRHKKSHTEEKPYK---CEECGKGFKWPSTLTIHKIIHTGEKPYKCEECGKAF 519
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
S L H K HTG+K ++C C AF+ +L H R+HTG KP+KC C+ F+ S
Sbjct: 520 NQSSKLTKHKKIHTGEKPYTCEECGKAFNQSSNLTKHKRIHTGEKPYKCEECDKAFKWSS 579
Query: 1265 RRKTHMQFH 1273
H H
Sbjct: 580 VLTKHKIIH 588
Score = 194 bits (494), Expect = 5e-49
Identities = 112/342 (32%), Positives = 160/342 (46%), Gaps = 21/342 (6%)
Query: 478 GVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKA 537
G + + C C K F + S L H IHT EKP+KC +C +AF STLT H K HTG K
Sbjct: 254 GEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKP 313
Query: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIA----------- 586
+KC+ C K+F S +L H +HTG +P+ C C K F S H TH
Sbjct: 314 YKCEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYKCE 373
Query: 587 ------SHFKHTELRKMRHQ-RKPAKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPKN 638
+HF H K+ H KP K + GK + + I + +
Sbjct: 374 KCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEK 433
Query: 639 QFFQS--YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVS 696
F QS + ++ ++PY+C C +A+ +S +L +H +SHT EKP+KC +CG+GF
Sbjct: 434 AFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTEEKPYKCEECGKGFKW 493
Query: 697 AGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNC 756
L H HTG K +KC C AF L +H IH +PY C C K F S N
Sbjct: 494 PSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSSNL 553
Query: 757 KKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQV 798
KH + H E + ++ +A + + ++Q+
Sbjct: 554 TKHKRIHTGEKPYKCEECDKAFKWSSVLTKHKIIHTGEKLQI 595
Score = 191 bits (486), Expect = 4e-48
Identities = 109/280 (38%), Positives = 140/280 (50%), Gaps = 22/280 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + S H H +KP++C +C + FN +LT H+ H+GE P C
Sbjct: 314 YKCEECGKAFKQSSNLTTHKIIHT-GEKPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYKC 372
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+ + L H ++H E+ C ECG F S L H H G + + C
Sbjct: 373 EKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIH----TGEKPYKC 428
Query: 156 KACKKEFETSSELKEHMKTHY--------KIRVSSTRSYNRNIDRSGFT----YSCPHCG 203
K C+K F SS+L EH K H K + +S N + T Y C CG
Sbjct: 429 KECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTEEKPYKCEECG 488
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ PS LT H IHTGE+P+KC ECGKAFNQ L H HTGEKP+ C C AF+
Sbjct: 489 KGFKWPSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFN 548
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
Q NL H +R+H+ K Y C EC FK L H
Sbjct: 549 QSSNLTKH-KRIHTGEK---PYKCEECDKAFKWSSVLTKH 584
Score = 190 bits (482), Expect = 1e-47
Identities = 108/300 (36%), Positives = 151/300 (50%), Gaps = 25/300 (8%)
Query: 18 GVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNV 77
G+++ E++ +V NF+KCE C +F S +H R H +KP++C++C + FN
Sbjct: 184 GMISCLTEHSRIHTRV-NFYKCEECGKAFNWSSTLTKHKRIHT-GEKPYKCEECGKAFNQ 241
Query: 78 EFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQL 136
NL HK H+GE P C C K F+R ++L H ++H E+ C ECG F S L
Sbjct: 242 SSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTL 301
Query: 137 AVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH-----YKIRVSSTRSYNRN-- 189
H + H G + + C+ C K F+ SS L H H YK + +++N++
Sbjct: 302 TTHRKIH----TGEKPYKCEECGKAFKQSSNLTTHKIIHTGEKPYKCK-KCGKAFNQSAH 356
Query: 190 ------IDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTH 243
I Y C CGK F S LT H IHTGE+P+KC ECGKAF L H
Sbjct: 357 LTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKH 416
Query: 244 MIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
I HTGEKP+ C C AF+Q L H +++H+ K Y C +C F +L H
Sbjct: 417 KIIHTGEKPYKCKECEKAFNQSSKLTEH-KKIHTGEK---PYECEKCGKAFNQSSNLTRH 472
Score = 190 bits (482), Expect = 1e-47
Identities = 106/329 (32%), Positives = 148/329 (44%), Gaps = 24/329 (7%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C+ C K F + S L H HTGEKPYKCK CG+ F S L +H K HTG K +
Sbjct: 256 KPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYK 315
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + +LT H H KPYKC C + F + H H H TG
Sbjct: 316 CEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIH---------TG 366
Query: 1085 ETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRP--QESATVSEKVLVQS 1142
E + H + K I T E+ + + + S+T+++ ++ +
Sbjct: 367 EKPYKCEKCGKAFNHFSHLTTHK-----IIHTGEKPYKCKECGKAFKHSSTLTKHKIIHT 421
Query: 1143 AAEKDRISELRDKQAELQDEPKHANC--------CTYCPKSFKKPSDLVRHVRIHTGEKP 1194
+ + E + +H C C K+F + S+L RH + HT EKP
Sbjct: 422 GEKPYKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTEEKP 481
Query: 1195 YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCP 1254
YKC+ECGK F STL H HTG+K + C C AF+ L H ++HTG KP+ C
Sbjct: 482 YKCEECGKGFKWPSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKHKKIHTGEKPYTCE 541
Query: 1255 HCELRFRTSGRRKTHMQFHYKPDPKKARK 1283
C F S H + H P K +
Sbjct: 542 ECGKAFNQSSNLTKHKRIHTGEKPYKCEE 570
Score = 186 bits (472), Expect = 2e-46
Identities = 107/280 (38%), Positives = 140/280 (50%), Gaps = 22/280 (7%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KCE C +F + S +H + H +KP++C++C +TFN LT HK H+GE P C
Sbjct: 230 YKCEECGKAFNQSSNLIKHKKIHT-GEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKC 288
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F+R ++L H +H E+ C ECG F S L H H G + + C
Sbjct: 289 KECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIH----TGEKPYKC 344
Query: 156 KACKKEFETSSELKEHMKTH-----YKIRVS-------STRSYNRNIDRSGFTYSCPHCG 203
K C K F S+ L H H YK S + ++ I Y C CG
Sbjct: 345 KKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECG 404
Query: 204 KTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFS 263
K F+ S LT+H IHTGE+P+KC EC KAFNQ L H HTGEKP+ C C AF+
Sbjct: 405 KAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFN 464
Query: 264 QKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTH 303
Q NL H ++ H+E K Y C EC FK +L H
Sbjct: 465 QSSNLTRH-KKSHTEEK---PYKCEECGKGFKWPSTLTIH 500
Score = 182 bits (463), Expect = 2e-45
Identities = 108/319 (33%), Positives = 142/319 (44%), Gaps = 36/319 (11%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
Y+C+ C K F SS L +H R HTGEKPYKC+ CG+ F S L H+K HTG K + C
Sbjct: 202 YKCEECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCE 261
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGET 1086
C +F +LT H H KPYKC C + F + H K H TGE
Sbjct: 262 ECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIH---------TGEK 312
Query: 1087 EGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRP--QESATVSEKVLVQSAA 1144
+ EE S I T E+ + K +SA ++ ++ +
Sbjct: 313 P-----YKCEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIHTGE 367
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
+ + C C K+F S L H IHTGEKPYKC ECGK+F
Sbjct: 368 KPYK--------------------CEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAF 407
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
STL H HTG+K + C C AF+ L H ++HTG KP++C C F S
Sbjct: 408 KHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSS 467
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
H + H + P K +
Sbjct: 468 NLTRHKKSHTEEKPYKCEE 486
Score = 171 bits (434), Expect = 5e-42
Identities = 152/622 (24%), Positives = 236/622 (37%), Gaps = 82/622 (13%)
Query: 93 PTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQ 152
P C ++ S+K H ++ K ++CS + + + ++ + G +
Sbjct: 50 PDLITCLEQGKEAWSMKRHEIMVAKP-TVMCSHFAQDLWPEQNIKDSFQKVTLKRYGKCR 108
Query: 153 HACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQL 212
H +K E+ E K H + T + ++ + C K K S
Sbjct: 109 HENLPLRKGCESMDECKMHKGGCNGLNQCLTATQSK-------IFQCDKYVKVAHKFSNS 161
Query: 213 TRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHV 272
RH HT ++PFKC++CGK+F L H HT + C C AF+ L H
Sbjct: 162 NRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEECGKAFNWSSTLTKH- 220
Query: 273 QRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQT 332
+R+H+ K Y C EC F +L H K+H G T F T
Sbjct: 221 KRIHTGEK---PYKCEECGKAFNQSSNLIKH-KKIHTGEKPYKCEECGK----TFNRFST 272
Query: 333 LPLQQTEAQATSASSQP-SSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQD 391
L T + +P + + L+ + +G+ P ++
Sbjct: 273 L----TTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECG-------- 320
Query: 392 ILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESP 451
+A + S + H + + A N+ T E E P
Sbjct: 321 ---KAFKQSSNLTTHKIIHTGEKPYKCKKCGKA--------FNQSAHLTTHEVIHTGEKP 369
Query: 452 EKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFK 511
K +K K L G + + C C K F+ S L +H IHT EKP+K
Sbjct: 370 YKCEKCGKAF--NHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYK 427
Query: 512 CPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHC 571
C +C +AF S LT H K HTG K ++C+ C K+F+ S +L H + HT +P+ C C
Sbjct: 428 CKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTEEKPYKCEEC 487
Query: 572 DKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGL 631
K F+ H H ++P + G
Sbjct: 488 GKGFKWPSTLTIHKIIHTG------------------------------EKPYKCEECG- 516
Query: 632 IQPIPKNQFFQS--YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQ 689
F QS + ++ ++PY C C +A+ +S +L +H R HTGEKP+KC +
Sbjct: 517 ------KAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSSNLTKHKRIHTGEKPYKCEE 570
Query: 690 CGRGFVSAGVLKAHIRTHTGLK 711
C + F + VL H HTG K
Sbjct: 571 CDKAFKWSSVLTKHKIIHTGEK 592
Score = 171 bits (432), Expect = 8e-42
Identities = 95/286 (33%), Positives = 136/286 (47%), Gaps = 34/286 (11%)
Query: 965 RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFS 1024
+ Y+C C K F +S+HL H HTGEKPYKC+ CG+ F L +H+ HTG K +
Sbjct: 340 KPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYK 399
Query: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATG 1084
C C +F + +LT+H H KPYKC CE+ F + +H K H TG
Sbjct: 400 CKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLTEHKKIH---------TG 450
Query: 1085 ETEGG-DICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSA 1143
E + C + + S+ +KS E + EE + K +T++ ++ +
Sbjct: 451 EKPYECEKCGKAFNQSSNLTRHKKSHTEEKPYKCEECGKGFKW----PSTLTIHKIIHTG 506
Query: 1144 AEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKS 1203
+ + C C K+F + S L +H +IHTGEKPY C+ECGK+
Sbjct: 507 EKPYK--------------------CEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKA 546
Query: 1204 FTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249
F S L H + HTG+K + C C AF L H +HTG K
Sbjct: 547 FNQSSNLTKHKRIHTGEKPYKCEECDKAFKWSSVLTKHKIIHTGEK 592
Score = 164 bits (416), Expect = 6e-40
Identities = 100/319 (31%), Positives = 138/319 (43%), Gaps = 8/319 (2%)
Query: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCS 1026
++CD K K S+ +H HT +KP+KC CG+ F L H + HT V + C
Sbjct: 146 FQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCE 205
Query: 1027 VCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ-TVPSAVSATGE 1085
C +F + +LT+H H KPYKC C + F + + KH K H P G+
Sbjct: 206 ECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGK 265
Query: 1086 TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQL-AKIRPQESATVSEKVLVQSAA 1144
T + + K + F T KI E E+ A
Sbjct: 266 TFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEEC---GKA 322
Query: 1145 EKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSF 1204
K + K ++P C C K+F + + L H IHTGEKPYKC++CGK+F
Sbjct: 323 FKQSSNLTTHKIIHTGEKPYK---CKKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAF 379
Query: 1205 TVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSG 1264
S L H HTG+K + C C AF +L H +HTG KP+KC CE F S
Sbjct: 380 NHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSS 439
Query: 1265 RRKTHMQFHYKPDPKKARK 1283
+ H + H P + K
Sbjct: 440 KLTEHKKIHTGEKPYECEK 458
Score = 164 bits (414), Expect = 1e-39
Identities = 93/282 (32%), Positives = 130/282 (46%), Gaps = 41/282 (14%)
Query: 484 CPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYC 543
C K K S+ RH HT +KPFKC +C ++F + S LT H + HT + +KC+ C
Sbjct: 148 CDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEEC 207
Query: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKP 603
K+F+ S +L H R+HTG +P+ C C K F S + H +K+ KP
Sbjct: 208 GKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKH----------KKIHTGEKP 257
Query: 604 AKVR-VGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYC 662
K GKT F + + ++ ++PYKC C
Sbjct: 258 YKCEECGKTF--------------------------NRFSTLTTHKIIHTGEKPYKCKEC 291
Query: 663 HRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAF 722
+A+ +S L H + HTGEKP+KC +CG+ F + L H HTG K +KC C AF
Sbjct: 292 GKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAF 351
Query: 723 TTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHR 764
L H IH +PY C C K F N H+ TH+
Sbjct: 352 NQSAHLTTHEVIHTGEKPYKCEKCGKAF----NHFSHLTTHK 389
Score = 152 bits (383), Expect = 4e-36
Identities = 81/216 (37%), Positives = 109/216 (50%), Gaps = 22/216 (10%)
Query: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TC 95
+KC+ C +F S +H H +KP++C +C + FN LT HK H+GE P C
Sbjct: 398 YKCKECGKAFKHSSTLTKHKIIHT-GEKPYKCKECEKAFNQSSKLTEHKKIHTGEKPYEC 456
Query: 96 PVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHAC 155
C K F++ ++L H H +E+ C ECG F S L +H H G + + C
Sbjct: 457 EKCGKAFNQSSNLTRHKKSHTEEKPYKCEECGKGFKWPSTLTIHKIIH----TGEKPYKC 512
Query: 156 KACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRH 215
+ C K F SS+L +H K H + Y+C CGK F + S LT+H
Sbjct: 513 EECGKAFNQSSKLTKHKKIHTGEK----------------PYTCEECGKAFNQSSNLTKH 556
Query: 216 IRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEK 251
RIHTGE+P+KC EC KAF L H I HTGEK
Sbjct: 557 KRIHTGEKPYKCEECDKAFKWSSVLTKHKIIHTGEK 592
Score = 125 bits (314), Expect = 4e-28
Identities = 62/148 (41%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC++AF+ ++ L H K++H E+ + C C KAF ++++L H ++H
Sbjct: 424 KPYKCKECEKAFNQSSKLTEH-KKIHTGEKPYECEKCGKAFNQSSNLTRHKKSH------ 476
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC+ C K F PS L H IHTGE+P+ C C KAFNQ S L H K HTG
Sbjct: 477 TEEKP--YKCEECGKGFKWPSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKHKKIHTG 534
Query: 1775 ERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
E+PY C C F Q SN+ H KR H+
Sbjct: 535 EKPYTCEECGKAFNQSSNLTKH-KRIHT 561
Score = 122 bits (305), Expect = 4e-27
Identities = 68/173 (39%), Positives = 93/173 (53%), Gaps = 11/173 (6%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + ++C +C +AF+ +A L H + +H E+ + C
Sbjct: 316 CEECG-KAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTH-EVIHTGEKPYKCE 373
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF +HL H H + +KP +KC C KAF S L +H IHTGE+P
Sbjct: 374 KCGKAFNHFSHLTTHKIIH------TGEKP--YKCKECGKAFKHSSTLTKHKIIHTGEKP 425
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHS 1802
+ C CEKAFNQ S L H K HTGE+PY+C C F Q SN+ H K++H+
Sbjct: 426 YKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRH-KKSHT 477
Score = 121 bits (303), Expect = 7e-27
Identities = 79/265 (29%), Positives = 104/265 (39%), Gaps = 41/265 (15%)
Query: 505 THEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVR 564
T K F+C + + S H HT K FKC C KSF L H R+HT V
Sbjct: 141 TQSKIFQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVN 200
Query: 565 PFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVR-VGKTNIPVPDIPLQEP 623
+ C C K F S H +++ KP K GK
Sbjct: 201 FYKCEECGKAFNWSSTLTKH----------KRIHTGEKPYKCEECGKA------------ 238
Query: 624 ILITDLGLIQPIPKNQFFQS--YFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTG 681
F QS + ++ ++PYKC C + + + L H HTG
Sbjct: 239 ----------------FNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTG 282
Query: 682 EKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPY 741
EKP+KC +CG+ F + L H + HTG K +KC C AF +L H IH +PY
Sbjct: 283 EKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIHTGEKPY 342
Query: 742 MCPYCQKTFKTSLNCKKHMKTHRYE 766
C C K F S + H H E
Sbjct: 343 KCKKCGKAFNQSAHLTTHEVIHTGE 367
Score = 119 bits (297), Expect = 4e-26
Identities = 58/140 (41%), Positives = 83/140 (59%), Gaps = 9/140 (6%)
Query: 1657 HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSS 1716
++C EC +AF+ ++ L H K +H E+ + C C KAF ++++L +H + H +
Sbjct: 202 YKCEECGKAFNWSSTLTKH-KRIHTGEKPYKCEECGKAFNQSSNLIKHKKIH------TG 254
Query: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGER 1776
+KP +KC+ C K F + S L H IHTGE+P+ C C KAFN+ S L H K HTGE+
Sbjct: 255 EKP--YKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEK 312
Query: 1777 PYKCAYCVMGFTQKSNMKLH 1796
PYKC C F Q SN+ H
Sbjct: 313 PYKCEECGKAFKQSSNLTTH 332
Score = 117 bits (294), Expect = 8e-26
Identities = 59/142 (41%), Positives = 83/142 (58%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C +C +AF+ + L H K +H E+ + C C KAFK ++ L +H H
Sbjct: 368 KPYKCEKCGKAFNHFSHLTTH-KIIHTGEKPYKCKECGKAFKHSSTLTKHKIIH------ 420
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC CEKAF + S+L H +IHTGE+P+ C C KAFNQ S L H K HT
Sbjct: 421 TGEKP--YKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTE 478
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C GF S + +H
Sbjct: 479 EKPYKCEECGKGFKWPSTLTIH 500
Score = 114 bits (284), Expect = 1e-24
Identities = 62/167 (37%), Positives = 87/167 (52%), Gaps = 10/167 (5%)
Query: 1630 CEEIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCP 1689
CEE + S NL + + ++C EC + F+ + L H K +H E+ + C
Sbjct: 232 CEECG-KAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTH-KIIHTGEKPYKCK 289
Query: 1690 VCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP 1749
C KAF R++ L H + H + +KP +KC+ C KAF + S L H IHTGE+P
Sbjct: 290 ECGKAFNRSSTLTTHRKIH------TGEKP--YKCEECGKAFKQSSNLTTHKIIHTGEKP 341
Query: 1750 FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796
+ C C KAFNQ + L H HTGE+PYKC C F S++ H
Sbjct: 342 YKCKKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTH 388
Score = 112 bits (280), Expect = 3e-24
Identities = 56/142 (39%), Positives = 80/142 (56%), Gaps = 9/142 (6%)
Query: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSL 1714
+ ++C EC +AF+ ++ L+ H K++H E+ + C C K F R + L H H
Sbjct: 228 KPYKCEECGKAFNQSSNLIKH-KKIHTGEKPYKCEECGKTFNRFSTLTTHKIIH------ 280
Query: 1715 SSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTG 1774
+ +KP +KC C KAF + S L H +IHTGE+P+ C C KAF Q S L H HTG
Sbjct: 281 TGEKP--YKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIHTG 338
Query: 1775 ERPYKCAYCVMGFTQKSNMKLH 1796
E+PYKC C F Q +++ H
Sbjct: 339 EKPYKCKKCGKAFNQSAHLTTH 360
Score = 112 bits (279), Expect = 4e-24
Identities = 54/141 (38%), Positives = 79/141 (56%), Gaps = 9/141 (6%)
Query: 1658 QCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQ 1717
+C +C ++F + L HS+ +H R + C C KAF ++ L +H + H + +
Sbjct: 175 KCTKCGKSFGMISCLTEHSR-IHTRVNFYKCEECGKAFNWSSTLTKHKRIH------TGE 227
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
KP +KC+ C KAF + S L +H +IHTGE+P+ C C K FN+ S L H HTGE+P
Sbjct: 228 KP--YKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEKP 285
Query: 1778 YKCAYCVMGFTQKSNMKLHMK 1798
YKC C F + S + H K
Sbjct: 286 YKCKECGKAFNRSSTLTTHRK 306
Score = 105 bits (262), Expect = 4e-22
Identities = 71/241 (29%), Positives = 98/241 (40%), Gaps = 45/241 (18%)
Query: 531 THTGIKAFKC-QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT----SGHRKTHI 585
T T K F+C +Y + S S + IR HT +PF C C K F + H + H
Sbjct: 139 TATQSKIFQCDKYVKVAHKFSNSNRHEIR-HTKKKPFKCTKCGKSFGMISCLTEHSRIHT 197
Query: 586 ASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYF 645
+F E GK + +
Sbjct: 198 RVNFYKCE-------------ECGKAF--------------------------NWSSTLT 218
Query: 646 NNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIR 705
+ ++ ++PYKC C +A+ +S +L +H + HTGEKP+KC +CG+ F L H
Sbjct: 219 KHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKI 278
Query: 706 THTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY 765
HTG K +KC C AF +L H IH +PY C C K FK S N H H
Sbjct: 279 IHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIHTG 338
Query: 766 E 766
E
Sbjct: 339 E 339
Score = 105 bits (262), Expect = 4e-22
Identities = 55/136 (40%), Positives = 69/136 (50%), Gaps = 3/136 (2%)
Query: 1158 ELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217
E++ K CT C KSF S L H RIHT YKC+ECGK+F STL H + H
Sbjct: 165 EIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEECGKAFNWSSTLTKHKRIH 224
Query: 1218 TGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPD 1277
TG+K + C C AF+ +L H ++HTG KP+KC C F TH H
Sbjct: 225 TGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEK 284
Query: 1278 PKKAR---KPMTRSSS 1290
P K + K RSS+
Sbjct: 285 PYKCKECGKAFNRSST 300
Score = 96.7 bits (239), Expect = 2e-19
Identities = 51/138 (36%), Positives = 71/138 (51%), Gaps = 10/138 (7%)
Query: 1661 ECDRAFSSAAVLMHHSKEV--HGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQK 1718
+CD+ A + ++ H +++ C C K+F + L EH + H +
Sbjct: 147 QCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIH--------TR 198
Query: 1719 PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPY 1778
+KC+ C KAF S L +H RIHTGE+P+ C C KAFNQ S L H K HTGE+PY
Sbjct: 199 VNFYKCEECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPY 258
Query: 1779 KCAYCVMGFTQKSNMKLH 1796
KC C F + S + H
Sbjct: 259 KCEECGKTFNRFSTLTTH 276
Score = 95.9 bits (237), Expect = 3e-19
Identities = 50/136 (36%), Positives = 74/136 (54%), Gaps = 9/136 (6%)
Query: 1641 SGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATH 1700
S NL + E + ++C EC + F + L H K +H E+ + C C KAF +++
Sbjct: 466 SSNLTRHKKSHTEEKPYKCEECGKGFKWPSTLTIH-KIIHTGEKPYKCEECGKAFNQSSK 524
Query: 1701 LKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFN 1760
L +H + H + +KP + C+ C KAF + S L +H RIHTGE+P+ C C+KAF
Sbjct: 525 LTKHKKIH------TGEKP--YTCEECGKAFNQSSNLTKHKRIHTGEKPYKCEECDKAFK 576
Query: 1761 QKSALQVHMKKHTGER 1776
S L H HTGE+
Sbjct: 577 WSSVLTKHKIIHTGEK 592
Score = 80.5 bits (197), Expect = 1e-14
Identities = 39/81 (48%), Positives = 45/81 (55%)
Query: 1718 KPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP 1777
K + FKC C K+F S L HSRIHT + C C KAFN S L H + HTGE+P
Sbjct: 170 KKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEECGKAFNWSSTLTKHKRIHTGEKP 229
Query: 1778 YKCAYCVMGFTQKSNMKLHMK 1798
YKC C F Q SN+ H K
Sbjct: 230 YKCEECGKAFNQSSNLIKHKK 250
Score = 50.4 bits (119), Expect = 2e-05
Identities = 43/189 (22%), Positives = 72/189 (38%), Gaps = 15/189 (7%)
Query: 1108 SRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHAN 1167
S+P++IT E+ + A + V++ ++ S +D E K + + K
Sbjct: 48 SKPDLITCLEQ--GKEAWSMKRHEIMVAKPTVMCSHFAQDLWPEQNIKDSFQKVTLKRYG 105
Query: 1168 CCTYCPKSFKKPSDLVRHVRIHTG-------------EKPYKCDECGKSFTVKSTLDCHV 1214
C + +K + + ++H G K ++CD+ K S + H
Sbjct: 106 KCRHENLPLRKGCESMDECKMHKGGCNGLNQCLTATQSKIFQCDKYVKVAHKFSNSNRHE 165
Query: 1215 KTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY 1274
HT +K F C C +F L H R+HT +KC C F S H + H
Sbjct: 166 IRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEECGKAFNWSSTLTKHKRIHT 225
Query: 1275 KPDPKKARK 1283
P K +
Sbjct: 226 GEKPYKCEE 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,773,988
Number of Sequences: 37866
Number of extensions: 3861823
Number of successful extensions: 154086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1090
Number of HSP's successfully gapped in prelim test: 296
Number of HSP's that attempted gapping in prelim test: 16077
Number of HSP's gapped (non-prelim): 49454
length of query: 1845
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1728
effective length of database: 13,817,196
effective search space: 23876114688
effective search space used: 23876114688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.