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Search of human proteins with 6857820
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 825 0.0
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 645 0.0
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 525 e-149
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 525 e-149
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 481 e-136
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,... 459 e-129
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 164 2e-40
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 164 2e-40
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al... 164 2e-40
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be... 161 1e-39
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g... 159 6e-39
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 145 5e-35
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 103 3e-22
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 65 1e-10
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso... 61 2e-09
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 35 0.16
gi|93141033 PAX interacting protein 1 [Homo sapiens] 34 0.27
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 33 0.46
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 33 0.46
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 33 0.46
gi|57242807 zinc finger protein 518 [Homo sapiens] 33 0.46
gi|224589135 RGM domain family, member B [Homo sapiens] 32 0.79
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 32 0.79
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 32 0.79
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 32 0.79
gi|38373682 pleckstrin homology domain containing family G membe... 32 0.79
gi|111154084 pleckstrin homology domain containing family G memb... 32 0.79
gi|111154088 pleckstrin homology domain containing family G memb... 32 0.79
gi|111154080 pleckstrin homology domain containing family G memb... 32 0.79
gi|111154078 pleckstrin homology domain containing family G memb... 32 0.79
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
Length = 406
Score = 825 bits (2130), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVM 60
MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVM
Sbjct: 1 MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVM 60
Query: 61 LMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSA 120
LMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSA
Sbjct: 61 LMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSA 120
Query: 121 PLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLG 180
PLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLG
Sbjct: 121 PLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLG 180
Query: 181 MYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFIN 240
MYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFIN
Sbjct: 181 MYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFIN 240
Query: 241 EGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEE 300
EGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEE
Sbjct: 241 EGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEE 300
Query: 301 EGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDI 360
EGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDI
Sbjct: 301 EGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDI 360
Query: 361 LTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT 406
LTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT
Sbjct: 361 LTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT 406
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 645 bits (1665), Expect = 0.0
Identities = 314/399 (78%), Positives = 357/399 (89%), Gaps = 5/399 (1%)
Query: 13 ASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKI 72
ASKTKTKKKHFV QKVKLFRAS+P+LSVLMWGVNH+INELS+V +PVMLMPDDFKAYSKI
Sbjct: 18 ASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKI 77
Query: 73 KVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGA 132
KVDNHLFNKEN+PS FKFKEYCPMVFRNLRERFGIDDQD+QNS+TRSAP+ +DSQ R G
Sbjct: 78 KVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGT 137
Query: 133 RFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIY 192
RF T+YD+R++IKT++SEDVAEMHNILKKYHQ+IVECHG TLLPQFLGMYRL VDGVE Y
Sbjct: 138 RFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETY 197
Query: 193 VIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNK 252
++VTRNVFSHRL+V+RKYDLKGSTVAREASDKEKAK+LPT KDNDF+NEGQK+++ + +K
Sbjct: 198 MVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESK 257
Query: 253 KVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTH---- 308
K FLEKLK+DVEFLAQLK+MDYSLLVGIHDV+RAEQEE+E EE +EE E+DG
Sbjct: 258 KNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLL 317
Query: 309 -PVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
GTPPDSPGN L+ PGEFDP++DVY +K HE+SP+KEVYFMAIIDILT YD K
Sbjct: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
Query: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT 406
KKAAHAAKTVKHGAGAEISTVNPEQYSKRF +F+ +ILT
Sbjct: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 416
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 525 bits (1352), Expect = e-149
Identities = 260/397 (65%), Positives = 316/397 (79%), Gaps = 11/397 (2%)
Query: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+ SLTR+ P ++ S RF
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 142
Query: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
SYD+ +IK ++SED+A+MH+ L YHQYIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
Query: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
Query: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
Query: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
Query: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 525 bits (1352), Expect = e-149
Identities = 260/397 (65%), Positives = 316/397 (79%), Gaps = 11/397 (2%)
Query: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+ SLTR+ P ++ S RF
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 142
Query: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
SYD+ +IK ++SED+A+MH+ L YHQYIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
Query: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
Query: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
Query: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
Query: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 481 bits (1237), Expect = e-136
Identities = 246/397 (61%), Positives = 298/397 (75%), Gaps = 29/397 (7%)
Query: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIK
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIK-- 83
Query: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
EYCP VFRNLR+RFGIDDQD+ SLTR+ P ++ S RF
Sbjct: 84 ----------------EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 124
Query: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
SYD+ +IK ++SED+A+MH+ L YHQYIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 125 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 184
Query: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 185 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 244
Query: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 245 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 304
Query: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 305 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 364
Query: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 365 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 401
>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform c [Homo sapiens]
Length = 373
Score = 459 bits (1181), Expect = e-129
Identities = 237/397 (59%), Positives = 283/397 (71%), Gaps = 59/397 (14%)
Query: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
NHLF++EN+PSHFKFKEYCP VFRNLR+RFGIDDQD+
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYL---------------------- 123
Query: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
YIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 124 -----------------------------YIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 154
Query: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 155 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 214
Query: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 215 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 274
Query: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 275 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 334
Query: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 335 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 371
>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 1 [Homo sapiens]
Length = 562
Score = 164 bits (414), Expect = 2e-40
Identities = 115/383 (30%), Positives = 185/383 (48%), Gaps = 34/383 (8%)
Query: 34 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87
S L + G+ H++ LS +LM D + V++ F E P+H
Sbjct: 82 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 135
Query: 88 -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146
F+FK Y P+ FR RE FGI D+ SL + S SG+ F+ S D +IIKT
Sbjct: 136 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 195
Query: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206
+ ++ + +L Y+ + + + TLLP+F G+Y + G I ++V N+ + +
Sbjct: 196 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 254
Query: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265
+ KYDLKGST R AS KE+ K LPT KD DF+ + +++D + + L++D
Sbjct: 255 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 314
Query: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSS- 324
L K+MDYSLL+ IH+++ A++E + S+ + V T +P L S+
Sbjct: 315 LQSFKIMDYSLLMSIHNIDHAQREPL-----------SSETQYSVDTRRPAPQKALYSTA 363
Query: 325 ------PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVK 378
G + + + GI + + + ++ IIDIL Y KK H+ K +
Sbjct: 364 MESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALV 423
Query: 379 HGAGAEISTVNPEQYSKRFLDFI 401
H G +S P Y++RF F+
Sbjct: 424 HD-GDTVSVHRPGFYAERFQRFM 445
>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
Length = 500
Score = 164 bits (414), Expect = 2e-40
Identities = 115/383 (30%), Positives = 185/383 (48%), Gaps = 34/383 (8%)
Query: 34 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87
S L + G+ H++ LS +LM D + V++ F E P+H
Sbjct: 69 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
Query: 88 -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146
F+FK Y P+ FR RE FGI D+ SL + S SG+ F+ S D +IIKT
Sbjct: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
Query: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206
+ ++ + +L Y+ + + + TLLP+F G+Y + G I ++V N+ + +
Sbjct: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
Query: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265
+ KYDLKGST R AS KE+ K LPT KD DF+ + +++D + + L++D
Sbjct: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
Query: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSS- 324
L K+MDYSLL+ IH+++ A++E + S+ + V T +P L S+
Sbjct: 302 LQSFKIMDYSLLMSIHNIDHAQREPL-----------SSETQYSVDTRRPAPQKALYSTA 350
Query: 325 ------PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVK 378
G + + + GI + + + ++ IIDIL Y KK H+ K +
Sbjct: 351 MESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALV 410
Query: 379 HGAGAEISTVNPEQYSKRFLDFI 401
H G +S P Y++RF F+
Sbjct: 411 HD-GDTVSVHRPGFYAERFQRFM 432
>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
isoform 2 [Homo sapiens]
Length = 549
Score = 164 bits (414), Expect = 2e-40
Identities = 115/383 (30%), Positives = 185/383 (48%), Gaps = 34/383 (8%)
Query: 34 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87
S L + G+ H++ LS +LM D + V++ F E P+H
Sbjct: 69 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
Query: 88 -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146
F+FK Y P+ FR RE FGI D+ SL + S SG+ F+ S D +IIKT
Sbjct: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
Query: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206
+ ++ + +L Y+ + + + TLLP+F G+Y + G I ++V N+ + +
Sbjct: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
Query: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265
+ KYDLKGST R AS KE+ K LPT KD DF+ + +++D + + L++D
Sbjct: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
Query: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSS- 324
L K+MDYSLL+ IH+++ A++E + S+ + V T +P L S+
Sbjct: 302 LQSFKIMDYSLLMSIHNIDHAQREPL-----------SSETQYSVDTRRPAPQKALYSTA 350
Query: 325 ------PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVK 378
G + + + GI + + + ++ IIDIL Y KK H+ K +
Sbjct: 351 MESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALV 410
Query: 379 HGAGAEISTVNPEQYSKRFLDFI 401
H G +S P Y++RF F+
Sbjct: 411 HD-GDTVSVHRPGFYAERFQRFM 432
>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
isoform 2 [Homo sapiens]
Length = 540
Score = 161 bits (407), Expect = 1e-39
Identities = 112/379 (29%), Positives = 182/379 (48%), Gaps = 22/379 (5%)
Query: 33 ASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKI--KVDNHLFNKENMPSHFKF 90
AS + + G+ +++ L+ +LM D + S ++L + P F+F
Sbjct: 25 ASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPD-FRF 83
Query: 91 KEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSE 150
K Y P+ FR RE FGI D+ S+ + + SG+ F + D +IIKT+ +
Sbjct: 84 KTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHK 143
Query: 151 DVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKY 210
+ + +L Y+ + + + TLLP+F G+Y + G+ I ++V NV + ++ Y
Sbjct: 144 EAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTY 202
Query: 211 DLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEFLAQL 269
DLKGST R AS KE+ K PT KD DF+ + + +Y D ++ L++D L
Sbjct: 203 DLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESF 262
Query: 270 KLMDYSLLVGIHDVERA-EQEEVECEEN--DGEEEGESDGTHPVGTP----PDSPGNTLN 322
K+MDYSLL+GIH ++ + +++E E +N D + G + P G+ +
Sbjct: 263 KIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGII 322
Query: 323 SSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAG 382
+ P G GI + K + FM IIDIL Y KK H+ K + + G
Sbjct: 323 TENPDTMG---------GIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-G 372
Query: 383 AEISTVNPEQYSKRFLDFI 401
+S P Y+ RFL F+
Sbjct: 373 DTVSVHRPSFYADRFLKFM 391
>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
gamma [Homo sapiens]
Length = 668
Score = 159 bits (401), Expect = 6e-39
Identities = 115/379 (30%), Positives = 183/379 (48%), Gaps = 22/379 (5%)
Query: 34 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87
S L + G+ +++ LS +LM D + V++ F E P+H
Sbjct: 76 SSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHFQ 129
Query: 88 -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146
F+FK Y P+ FR RE FGI D+ SL + + SG+ F+ + D +IIKT
Sbjct: 130 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKT 189
Query: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206
+ ++ + +L Y+ + + + TLLP+F G+Y + G I V+V N+ + +
Sbjct: 190 VMHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKM 248
Query: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265
+ K+DLKGST R AS KEK K PT KD DF+ + + + +D + ++ L++D
Sbjct: 249 HLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLV 308
Query: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSP 325
L K+MDYSLL+G+H++++ E+E + G + SD PVG +
Sbjct: 309 LESFKIMDYSLLLGVHNIDQHERE----RQAQG-AQSTSDEKRPVGQKALYSTAMESIQG 363
Query: 326 PLAPGEFDPNIDVY-GIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAE 384
A GE + D GI + + + IIDIL Y KK H K + H G
Sbjct: 364 GAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHD-GDT 422
Query: 385 ISTVNPEQYSKRFLDFIGH 403
+S P Y++RF F+ +
Sbjct: 423 VSVHRPSFYAERFFKFMSN 441
>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 3 [Homo sapiens]
Length = 522
Score = 145 bits (367), Expect = 5e-35
Identities = 89/269 (33%), Positives = 141/269 (52%), Gaps = 15/269 (5%)
Query: 34 SDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENM---PSH--- 87
S L + G+ H++ LS +LM D + V++ F E P+H
Sbjct: 70 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 123
Query: 88 -FKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKT 146
F+FK Y P+ FR RE FGI D+ SL + S SG+ F+ S D +IIKT
Sbjct: 124 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 183
Query: 147 ITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSV 206
+ ++ + +L Y+ + + + TLLP+F G+Y + G I ++V N+ + +
Sbjct: 184 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 242
Query: 207 YRKYDLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEF 265
+ KYDLKGST R AS KE+ K LPT KD DF+ + +++D + + L++D
Sbjct: 243 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 302
Query: 266 LAQLKLMDYSLLVGIHDVERAEQEEVECE 294
L K+MDYSLL+ IH+++ A++E + E
Sbjct: 303 LQSFKIMDYSLLMSIHNIDHAQREPLSSE 331
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
Length = 394
Score = 103 bits (257), Expect = 3e-22
Identities = 87/313 (27%), Positives = 150/313 (47%), Gaps = 37/313 (11%)
Query: 98 FRNLRERFGIDDQDFQNSLTRSAP-LPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMH 156
F LR G+ ++D+Q +L P L S ++S A F S+D+R+ +KT +V +
Sbjct: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
Query: 157 NILKKYHQYIVECHGITLLPQFLGMYRLNVD-GVEIYVIVTRNVFSHRLSVYRKYDLKGS 215
L +Y Q++ + H +LL + LG++ L VD G + Y IV ++VF + +YD+KG
Sbjct: 165 AHLPRYVQHL-QRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
Query: 216 TVAREASDKEKAKELP-TLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDY 274
V+R + L LKD +F +G+ I + + FL +++ D FL +L ++DY
Sbjct: 224 EVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
Query: 275 SLLVG---IHDVERAEQEEV---ECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLA 328
SLL+ +H+ ER + G + E PD+P N L
Sbjct: 281 SLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAP-NAL------- 332
Query: 329 PGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTV 388
H ++ YF+ ++D+ T Y +K+ H KT+++ G STV
Sbjct: 333 ---------------HILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFSTV 376
Query: 389 NPEQYSKRFLDFI 401
+P +Y++R ++
Sbjct: 377 SPARYARRLCQWV 389
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/209 (29%), Positives = 97/209 (46%), Gaps = 19/209 (9%)
Query: 91 KEYCPMV----FRNLRERF-GIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIK 145
K YC + F +RE ++DF SL+ S+P +SGA F+ + D R+I+K
Sbjct: 1819 KFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARG-GKSGAAFYATEDDRFILK 1877
Query: 146 TITSEDVAEMHNILKKYHQYI---VECHGITLLPQFLGMYRL------NVDGVEIYVIVT 196
+ +V + Y YI V+ T L + LG+YR+ N ++ ++V
Sbjct: 1878 QMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVM 1937
Query: 197 RNVFSHRLSVYRKYDLKGSTVAREA-SDKEKAKELPTLKDNDFIN--EGQKIYIDDNNKK 253
N+F R + + +DLKGS R +D K L D + + +YI ++K
Sbjct: 1938 ENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKA 1996
Query: 254 VFLEKLKKDVEFLAQLKLMDYSLLVGIHD 282
V + D FL+ ++DYSLLVG D
Sbjct: 1997 VLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 2 [Homo sapiens]
Length = 191
Score = 60.8 bits (146), Expect = 2e-09
Identities = 53/212 (25%), Positives = 94/212 (44%), Gaps = 34/212 (16%)
Query: 197 RNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELP-TLKDNDFINEGQKIYIDDNNKKVF 255
++VF + +YD+KG V+R + L LKD +F +G+ I + + F
Sbjct: 2 QSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWF 58
Query: 256 LEKLKKDVEFLAQLKLMDYSLLVG---IHDVERAEQEEV---ECEENDGEEEGESDGTHP 309
L +++ D FL +L ++DYSLL+ +H+ ER + G + E
Sbjct: 59 LRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQN 118
Query: 310 VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKK 369
PD+P N L H ++ YF+ ++D+ T Y +K+
Sbjct: 119 RRLLPDAP-NAL----------------------HILDGPEQRYFLGVVDLATVYGLRKR 155
Query: 370 AAHAAKTVKHGAGAEISTVNPEQYSKRFLDFI 401
H KT+++ G STV+P +Y++R ++
Sbjct: 156 LEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 34.7 bits (78), Expect = 0.16
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 12/96 (12%)
Query: 236 NDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVER---------- 285
ND E + + ++ + LE L+ FL + + + LVG + ER
Sbjct: 64 NDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEE 123
Query: 286 --AEQEEVECEENDGEEEGESDGTHPVGTPPDSPGN 319
E+EE E EE + EEE E + P P S GN
Sbjct: 124 GGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGN 159
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 33.9 bits (76), Expect = 0.27
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 257 EKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESD-GTHPVGTPPD 315
EK KKD F +L+ Y + E E+EEVE EE D + EG +D + P +
Sbjct: 172 EKTKKDEAFYHP-RLIIYEE----EEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEG 226
Query: 316 SPGNTLNSSP 325
SP SP
Sbjct: 227 SPSGDQQFSP 236
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 33.1 bits (74), Expect = 0.46
Identities = 32/157 (20%), Positives = 64/157 (40%), Gaps = 20/157 (12%)
Query: 174 LLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTL 233
L+ M +N G + + ++ + + +K +L S ++K L
Sbjct: 164 LVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHS------EKRDKKSPLIES 217
Query: 234 KDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVEC 293
N N+ QK + + + EK +E L Q K + + E +++E C
Sbjct: 218 TANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEK---------VDEEEEGKKDESSC 268
Query: 294 -----EENDGEEEGESDGTHPVGTPPDSPGNTLNSSP 325
EE+D E E E+D T P+ + ++ ++ ++P
Sbjct: 269 SSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAP 305
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 33.1 bits (74), Expect = 0.46
Identities = 32/157 (20%), Positives = 64/157 (40%), Gaps = 20/157 (12%)
Query: 174 LLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTL 233
L+ M +N G + + ++ + + +K +L S ++K L
Sbjct: 251 LVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHS------EKRDKKSPLIES 304
Query: 234 KDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVEC 293
N N+ QK + + + EK +E L Q K + + E +++E C
Sbjct: 305 TANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEK---------VDEEEEGKKDESSC 355
Query: 294 -----EENDGEEEGESDGTHPVGTPPDSPGNTLNSSP 325
EE+D E E E+D T P+ + ++ ++ ++P
Sbjct: 356 SSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAP 392
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 33.1 bits (74), Expect = 0.46
Identities = 32/157 (20%), Positives = 64/157 (40%), Gaps = 20/157 (12%)
Query: 174 LLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTL 233
L+ M +N G + + ++ + + +K +L S ++K L
Sbjct: 251 LVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHS------EKRDKKSPLIES 304
Query: 234 KDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVEC 293
N N+ QK + + + EK +E L Q K + + E +++E C
Sbjct: 305 TANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEK---------VDEEEEGKKDESSC 355
Query: 294 -----EENDGEEEGESDGTHPVGTPPDSPGNTLNSSP 325
EE+D E E E+D T P+ + ++ ++ ++P
Sbjct: 356 SSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAP 392
>gi|57242807 zinc finger protein 518 [Homo sapiens]
Length = 1483
Score = 33.1 bits (74), Expect = 0.46
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 239 INEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDG 298
IN G I+ N + L+K+ K Q K D S +V H + + E + CE ND
Sbjct: 333 INSGSDRSIEKNTQ--VLKKMNK-----TQTKSEDQSHVVQEH-LSEEKDERLHCENNDK 384
Query: 299 EEEGESDGTHPVGTPPDSPGNTLNSSPPLAPG 330
E ES+ P+ T GN P + G
Sbjct: 385 APESESEKPTPLST---GQGNRAEEGPNASSG 413
>gi|224589135 RGM domain family, member B [Homo sapiens]
Length = 478
Score = 32.3 bits (72), Expect = 0.79
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 336 IDVYGIKCHENSPRKEVYFMA-IIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQ 392
++ +CHE P K++YF + + D+LT DA AA H A ++ ++P +
Sbjct: 392 LETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAA------AHSALEDVEALHPRK 443
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 32.3 bits (72), Expect = 0.79
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 220 EASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVG 279
E ++E+ +E ++ DF E +++ ++ F E+ +++ EF + + + L
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEE------EEDEEEYFEEEEEEEEEFEEEFEEEEGELEE- 944
Query: 280 IHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPD---SPGNTLNSSPPLAPGEFDP 334
+ E E+EE E EE + E G + G G PP P SPP E +P
Sbjct: 945 -EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 32.3 bits (72), Expect = 0.79
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 282 DVERAEQEEVECEENDGEEEGES-DGTHPVGTPPDS-PGNTLNSSPPLAPGEFDPNIDVY 339
D E E EE + EE EEE E+ + PV P + P + PPL P + V
Sbjct: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
Query: 340 GIKCHENSPRKEVY-FMAIIDILTHYDAKKK 369
H K++ +ID+ H++ +KK
Sbjct: 63 FDDIHRKRMEKDLLELQTLIDV--HFEQRKK 91
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 32.3 bits (72), Expect = 0.79
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 282 DVERAEQEEVECEENDGEEEGES-DGTHPVGTPPDS-PGNTLNSSPPLAPGEFDPNIDVY 339
D E E EE + EE EEE E+ + PV P + P + PPL P + V
Sbjct: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
Query: 340 GIKCHENSPRKEVY-FMAIIDILTHYDAKKK 369
H K++ +ID+ H++ +KK
Sbjct: 63 FDDIHRKRMEKDLLELQTLIDV--HFEQRKK 91
>gi|38373682 pleckstrin homology domain containing family G member 5
isoform a [Homo sapiens]
Length = 1006
Score = 32.3 bits (72), Expect = 0.79
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 31/105 (29%)
Query: 284 ERAEQEEVECEENDGEEEGESDGTHPVGTP---------PDS------------------ 316
E EQEE E EE + EEEGE GT +P PDS
Sbjct: 707 EEDEQEEEE-EEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765
Query: 317 PGNTLNSSPPLAPGEFDPNIDVYGIKCHENS--PRKEVYFMAIID 359
PG+TL SSP G F D + +S P E+ + +D
Sbjct: 766 PGDTL-SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD 809
>gi|111154084 pleckstrin homology domain containing family G member
5 isoform b [Homo sapiens]
Length = 1083
Score = 32.3 bits (72), Expect = 0.79
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 31/105 (29%)
Query: 284 ERAEQEEVECEENDGEEEGESDGTHPVGTP---------PDS------------------ 316
E EQEE E EE + EEEGE GT +P PDS
Sbjct: 784 EEDEQEEEE-EEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 842
Query: 317 PGNTLNSSPPLAPGEFDPNIDVYGIKCHENS--PRKEVYFMAIID 359
PG+TL SSP G F D + +S P E+ + +D
Sbjct: 843 PGDTL-SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD 886
>gi|111154088 pleckstrin homology domain containing family G member
5 isoform a [Homo sapiens]
Length = 1006
Score = 32.3 bits (72), Expect = 0.79
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 31/105 (29%)
Query: 284 ERAEQEEVECEENDGEEEGESDGTHPVGTP---------PDS------------------ 316
E EQEE E EE + EEEGE GT +P PDS
Sbjct: 707 EEDEQEEEE-EEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765
Query: 317 PGNTLNSSPPLAPGEFDPNIDVYGIKCHENS--PRKEVYFMAIID 359
PG+TL SSP G F D + +S P E+ + +D
Sbjct: 766 PGDTL-SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD 809
>gi|111154080 pleckstrin homology domain containing family G member
5 isoform a [Homo sapiens]
Length = 1006
Score = 32.3 bits (72), Expect = 0.79
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 31/105 (29%)
Query: 284 ERAEQEEVECEENDGEEEGESDGTHPVGTP---------PDS------------------ 316
E EQEE E EE + EEEGE GT +P PDS
Sbjct: 707 EEDEQEEEE-EEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765
Query: 317 PGNTLNSSPPLAPGEFDPNIDVYGIKCHENS--PRKEVYFMAIID 359
PG+TL SSP G F D + +S P E+ + +D
Sbjct: 766 PGDTL-SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD 809
>gi|111154078 pleckstrin homology domain containing family G member
5 isoform c [Homo sapiens]
Length = 1062
Score = 32.3 bits (72), Expect = 0.79
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 31/105 (29%)
Query: 284 ERAEQEEVECEENDGEEEGESDGTHPVGTP---------PDS------------------ 316
E EQEE E EE + EEEGE GT +P PDS
Sbjct: 763 EEDEQEEEE-EEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 821
Query: 317 PGNTLNSSPPLAPGEFDPNIDVYGIKCHENS--PRKEVYFMAIID 359
PG+TL SSP G F D + +S P E+ + +D
Sbjct: 822 PGDTL-SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD 865
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,812,995
Number of Sequences: 37866
Number of extensions: 757802
Number of successful extensions: 4685
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 4433
Number of HSP's gapped (non-prelim): 201
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.