BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] (568 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 1153 0.0 gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 1147 0.0 gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 1140 0.0 gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 473 e-133 gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 456 e-128 gi|33563374 carboxylesterase 3 [Homo sapiens] 451 e-126 gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 429 e-120 gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 397 e-110 gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 365 e-101 gi|51593088 neuroligin 3 [Homo sapiens] 292 5e-79 gi|30840978 neuroligin 2 [Homo sapiens] 291 8e-79 gi|31317256 X-linked neuroligin 4 [Homo sapiens] 291 1e-78 gi|24308209 X-linked neuroligin 4 [Homo sapiens] 291 1e-78 gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 285 1e-76 gi|7662470 neuroligin 1 [Homo sapiens] 284 1e-76 gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 250 2e-66 gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 250 2e-66 gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 249 4e-66 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 233 3e-61 gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 195 1e-49 gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 194 2e-49 gi|55770862 thyroglobulin [Homo sapiens] 155 9e-38 gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 111 2e-24 gi|68299767 arylacetamide deacetylase [Homo sapiens] 42 0.001 gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap... 39 0.017 gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa... 37 0.037 gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 35 0.18 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 33 0.70 gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 33 0.92 gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 32 1.6 >gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] Length = 568 Score = 1153 bits (2983), Expect = 0.0 Identities = 568/568 (100%), Positives = 568/568 (100%) Query: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP Sbjct: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60 Query: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL Sbjct: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120 Query: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS Sbjct: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180 Query: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL Sbjct: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240 Query: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL Sbjct: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300 Query: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI Sbjct: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360 Query: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD Sbjct: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420 Query: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP Sbjct: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480 Query: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL Sbjct: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540 Query: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568 KDKEVAFWTNLFAKKAVEKPPQTEHIEL Sbjct: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568 >gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] Length = 567 Score = 1147 bits (2967), Expect = 0.0 Identities = 567/568 (99%), Positives = 567/568 (99%), Gaps = 1/568 (0%) Query: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60 MWLRAFILATLSASAAW GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP Sbjct: 1 MWLRAFILATLSASAAW-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 59 Query: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL Sbjct: 60 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 119 Query: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS Sbjct: 120 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 179 Query: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL Sbjct: 180 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 239 Query: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL Sbjct: 240 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 299 Query: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI Sbjct: 300 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 359 Query: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD Sbjct: 360 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 419 Query: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP Sbjct: 420 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 479 Query: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL Sbjct: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 539 Query: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568 KDKEVAFWTNLFAKKAVEKPPQTEHIEL Sbjct: 540 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 567 >gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] Length = 566 Score = 1140 bits (2950), Expect = 0.0 Identities = 566/568 (99%), Positives = 566/568 (99%), Gaps = 2/568 (0%) Query: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60 MWLRAFILATLSASAAW GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP Sbjct: 1 MWLRAFILATLSASAAW-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 59 Query: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL Sbjct: 60 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 119 Query: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS Sbjct: 120 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 179 Query: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL Sbjct: 180 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 239 Query: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL Sbjct: 240 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 299 Query: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI Sbjct: 300 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 359 Query: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420 PM LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD Sbjct: 360 PM-LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 418 Query: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP Sbjct: 419 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 478 Query: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL Sbjct: 479 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 538 Query: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568 KDKEVAFWTNLFAKKAVEKPPQTEHIEL Sbjct: 539 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 566 >gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] Length = 623 Score = 473 bits (1216), Expect = e-133 Identities = 260/557 (46%), Positives = 350/557 (62%), Gaps = 30/557 (5%) Query: 19 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 78 G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149 Query: 79 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 137 ++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207 Query: 138 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197 VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267 Query: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 256 ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++ Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327 Query: 257 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 316 DV ++ +A + C S +V CLR K++EE+L K Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372 Query: 317 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 376 ++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+ Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429 Query: 377 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 436 + + + L K L+ + E+Y+G D + F +++AD MF +P++ VA Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488 Query: 437 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDEL----FSVFGAPFLKEGASEEEIR 492 + + + AP Y YEFQ++PS+ +++P + DHGDEL S FG ++K +EEE + Sbjct: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIK--FTEEEEQ 546 Query: 493 LSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLF 552 LS+ +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW Sbjct: 547 LSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKAL 606 Query: 553 AKKAVE-KPPQTEHIEL 568 +K E + P+ H EL Sbjct: 607 PQKIQELEEPEERHTEL 623 >gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] Length = 607 Score = 456 bits (1174), Expect = e-128 Identities = 252/553 (45%), Positives = 340/553 (61%), Gaps = 38/553 (6%) Query: 19 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 78 G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149 Query: 79 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 137 ++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207 Query: 138 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197 VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267 Query: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 256 ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++ Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327 Query: 257 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 316 DV ++ +A + C S +V CLR K++EE+L K Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372 Query: 317 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 376 ++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+ Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429 Query: 377 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 436 + + + L K L+ + E+Y+G D + F +++AD MF +P++ VA Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488 Query: 437 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKM 496 + + + AP Y YEFQ++PS+ +++P + DH +EEE +LS+ Sbjct: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRK 534 Query: 497 VMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKA 556 +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K Sbjct: 535 MMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKI 594 Query: 557 VE-KPPQTEHIEL 568 E + P+ H EL Sbjct: 595 QELEEPEERHTEL 607 >gi|33563374 carboxylesterase 3 [Homo sapiens] Length = 571 Score = 451 bits (1159), Expect = e-126 Identities = 250/559 (44%), Positives = 345/559 (61%), Gaps = 38/559 (6%) Query: 11 LSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQ 70 L+ A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P Sbjct: 20 LACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPH 79 Query: 71 PAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTK 130 PA+PW V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ Sbjct: 80 PAQPWEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPA 137 Query: 131 KNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNW 190 + PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN Sbjct: 138 GSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQ 197 Query: 191 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 250 G LD VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV Sbjct: 198 GFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGV 257 Query: 251 ALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 310 T ++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K Sbjct: 258 ITTPGII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK------- 308 Query: 311 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 370 + +DG + K+P+EL E+ FH+VP+++G+N EF WLIP Sbjct: 309 ------NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPR-------G 355 Query: 371 EGQLDQKTAMS---LLWKSYPLVC---IAKELIPEATEKYLGGTDDTVKKKDLFLDLIAD 424 G LD MS +L S P++ + E++P ++YLG D K F + + D Sbjct: 356 WGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGD 415 Query: 425 VMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE 484 V VP+V +R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL + Sbjct: 416 VFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMD 475 Query: 485 --------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQA 536 A+EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A Sbjct: 476 ESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRA 535 Query: 537 AQKLKDKEVAFWTNLFAKK 555 QK ++ + FW+ K Sbjct: 536 GQKFREAWMQFWSETLPSK 554 >gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] Length = 575 Score = 429 bits (1104), Expect = e-120 Identities = 242/546 (44%), Positives = 322/546 (58%), Gaps = 33/546 (6%) Query: 14 SAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 73 +A G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79 Query: 74 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 133 PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++ Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253 DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+ Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257 Query: 254 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 310 L K +E + + A G + S ++ CLR K +ELL + K K + Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311 Query: 311 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 370 V+DG P +L +++ F +P ++G+N E G+L+PM+ LS Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360 Query: 371 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 430 ++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP Sbjct: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415 Query: 431 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK------E 484 ++I AR HRDAGAP Y YEF++RP D KP V DH DE+ VFG FLK E Sbjct: 416 ALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFE 475 Query: 485 GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKE 544 GA+EEE LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ Sbjct: 476 GATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPR 535 Query: 545 VAFWTN 550 V FWT+ Sbjct: 536 VDFWTS 541 >gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] Length = 491 Score = 397 bits (1019), Expect = e-110 Identities = 223/557 (40%), Positives = 316/557 (56%), Gaps = 79/557 (14%) Query: 8 LATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 67 L ++ +A A H P VV T +G + GK + + P+ +FLG+PF++PPLG LRF Sbjct: 11 LCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRPPLGILRFA 67 Query: 68 PPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPAD 127 PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLYLN+Y PA Sbjct: 68 PPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPAR 126 Query: 128 LTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSR 187 +LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF ST D H+R Sbjct: 127 APGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHAR 186 Query: 188 GNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISE 247 GNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA LFHRAIS+ Sbjct: 187 GNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQ 246 Query: 248 SGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSL 307 SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ + KM+FL L Sbjct: 247 SGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQL 305 Query: 308 DLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSY 367 + Q DP E + V+DG+++ P L + +VPY++G+N EF WL+P Sbjct: 306 NFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYN---- 361 Query: 368 PLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDLFLDLIADV 425 I KE +P E+YL + D ++ +D++ D Sbjct: 362 ------------------------ITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDA 397 Query: 426 MFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEG 485 F ++ A HR G KE Sbjct: 398 TFVYATLQTAHYHR--------------------------------------GLSMGKEK 419 Query: 486 ASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEV 545 A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+ KLK+K++ Sbjct: 420 A------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKM 473 Query: 546 AFWTNLFAKKAVEKPPQ 562 AFW +L+ + EK Q Sbjct: 474 AFWMSLYQSQRPEKQRQ 490 >gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] Length = 525 Score = 365 bits (937), Expect = e-101 Identities = 217/540 (40%), Positives = 294/540 (54%), Gaps = 71/540 (13%) Query: 14 SAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 73 +A G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79 Query: 74 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 133 PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++ Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253 DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+ Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257 Query: 254 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 310 L K +E + + A G + S ++ CLR K +ELL + K K + Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311 Query: 311 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 370 V+DG P +L +++ F +P ++G+N E G+L+PM+ LS Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360 Query: 371 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 430 ++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP Sbjct: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415 Query: 431 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEE 490 ++I AR HR EGA+EEE Sbjct: 416 ALITARYHR--------------------------------------------EGATEEE 431 Query: 491 IRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 550 LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+ Sbjct: 432 KLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491 >gi|51593088 neuroligin 3 [Homo sapiens] Length = 828 Score = 292 bits (748), Expect = 5e-79 Identities = 204/613 (33%), Positives = 293/613 (47%), Gaps = 90/613 (14%) Query: 4 RAFILATLSASAAWAGHPSSP-PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPL 61 R+ L S A +P P V+T GK+ G V L PV +LG+P+A PP+ Sbjct: 20 RSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPI 79 Query: 62 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SE 115 G RF PP+P WS ++NAT +PP+C Q+ +L FT + + + +E Sbjct: 80 GEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNE 139 Query: 116 DCLYLNIYTPA----------------------DLTKKNRLPVMVWIHGGGLMVGAASTY 153 DCLYLN+Y P D+ PVMV+IHGG M G + Sbjct: 140 DCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMI 199 Query: 154 DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNP 213 DG LA++ NV+V+T+ YR+G+ GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P Sbjct: 200 DGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDP 259 Query: 214 GSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITA 273 +T+FG G VS+L LS ++ LF RAI +SG AL+S V VK +A Sbjct: 260 RRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKV 318 Query: 274 GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTP 333 GC + MV CLRQK+ +EL+E ++ P G VIDG ++ P Sbjct: 319 GCNVLDTVDMVDCLRQKSAKELVEQDIQ-----------PARYHVAFGPVIDGDVIPDDP 367 Query: 334 EELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIA 393 E L + F M+G+N+ E EG +D + +S Y + Sbjct: 368 EILMEQGEFLNYDIMLGVNQGE----------GLKFVEGVVDPEDGVSGTDFDYSVSNFV 417 Query: 394 KEL--IPEA------TEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDA 441 L PE T K++ D+ ++ + L D + PSV+ A H Sbjct: 418 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY 477 Query: 442 GAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GASEEEIRLSK 495 G+PTY Y F + S MKP HGDE+ VFG P + S+ ++ LS Sbjct: 478 GSPTYFYAFYHH--CQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSA 535 Query: 496 MVMKFWANFARNGNPNGEGLPH----------------WPEYNQKEG-YLQIGANTQAAQ 538 +VM +W NFA+ G+PN + +P W +YN ++ YL IG + Sbjct: 536 VVMTYWTNFAKTGDPN-KPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRD 594 Query: 539 KLKDKEVAFWTNL 551 + +VAFW +L Sbjct: 595 HYRATKVAFWKHL 607 >gi|30840978 neuroligin 2 [Homo sapiens] Length = 835 Score = 291 bits (746), Expect = 8e-79 Identities = 202/621 (32%), Positives = 297/621 (47%), Gaps = 87/621 (14%) Query: 1 MWLRAFILATLSASAAWAGHPSSP-----------------PVVDTVHGKVLGKFVSLEG 43 MWL A L L+ + G P PVV+T +G+V G L Sbjct: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60 Query: 44 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 99 PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L Sbjct: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120 Query: 100 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 137 FT+ E + SEDCLYLN+Y P + LTKK + PVM Sbjct: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180 Query: 138 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197 +++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+ Sbjct: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240 Query: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 257 ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V Sbjct: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300 Query: 258 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 317 +K +A GC SA V CLR+K EL++ ++ P Sbjct: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348 Query: 318 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 377 G V+DG ++ PE L + F ++G+N+ E + S Sbjct: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDF 408 Query: 378 TAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVI 433 T + + Y K+++ E T K++ D+ ++ L L D + P+V Sbjct: 409 TVSNFVDNLYGYP-EGKDVLRE-TIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVA 466 Query: 434 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GAS 487 A+ H D +P Y Y F + ++ +P+ HGDEL VFG P + S Sbjct: 467 TAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFS 524 Query: 488 EEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKE-GYLQI 530 + ++ LS +VM +W NFA+ G+PN + +P W ++N KE YL I Sbjct: 525 KNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHI 583 Query: 531 GANTQAAQKLKDKEVAFWTNL 551 G + + +VAFW L Sbjct: 584 GLKPRVRDNYRANKVAFWLEL 604 >gi|31317256 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 291 bits (745), Expect = 1e-78 Identities = 193/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%) Query: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83 PVV+T +GK+ G L PV +LG+P+A PP G RF PP+P W+ ++N T Sbjct: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105 Query: 84 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 133 + +C Q LL ++ FT + + + +EDCLYLNIY P D+ +N + Sbjct: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 PVMV+IHGG M G + DG LA++ NV+V+TI YRLGI GF STGD+ ++GN+G L Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253 DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+ Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285 Query: 254 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 313 S V K +A GC + MV CLR K +EL++ T+ P Sbjct: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI-----------TP 333 Query: 314 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 373 G VIDG ++ P+ L + F M+G+N+ E +G Sbjct: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383 Query: 374 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 421 +D + ++ + + L PE T K++ ++ ++ + L Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481 D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501 Query: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519 + S+ ++ LS +VM +W NFA+ G+PN + +P W Sbjct: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560 Query: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551 +YN K+ YL IG + + +VAFW L Sbjct: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593 >gi|24308209 X-linked neuroligin 4 [Homo sapiens] Length = 816 Score = 291 bits (745), Expect = 1e-78 Identities = 193/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%) Query: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83 PVV+T +GK+ G L PV +LG+P+A PP G RF PP+P W+ ++N T Sbjct: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105 Query: 84 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 133 + +C Q LL ++ FT + + + +EDCLYLNIY P D+ +N + Sbjct: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 PVMV+IHGG M G + DG LA++ NV+V+TI YRLGI GF STGD+ ++GN+G L Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253 DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+ Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285 Query: 254 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 313 S V K +A GC + MV CLR K +EL++ T+ P Sbjct: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI-----------TP 333 Query: 314 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 373 G VIDG ++ P+ L + F M+G+N+ E +G Sbjct: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383 Query: 374 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 421 +D + ++ + + L PE T K++ ++ ++ + L Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481 D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501 Query: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519 + S+ ++ LS +VM +W NFA+ G+PN + +P W Sbjct: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560 Query: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551 +YN K+ YL IG + + +VAFW L Sbjct: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593 >gi|40538788 neuroligin 4, Y-linked [Homo sapiens] Length = 816 Score = 285 bits (728), Expect = 1e-76 Identities = 191/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%) Query: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83 PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT Sbjct: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105 Query: 84 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 133 + +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N + Sbjct: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253 DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+ Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285 Query: 254 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 313 S V K +A GC + MV CL+ K +EL++ T+ P Sbjct: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333 Query: 314 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 373 G VIDG ++ P+ L + F M+G+N+ E +G Sbjct: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383 Query: 374 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 421 +D + ++ + + L PE T K++ ++ ++ + L Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443 Query: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481 D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501 Query: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519 + S+ ++ LS +VM +W NFA+ G+PN + +P W Sbjct: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560 Query: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551 +YN K+ YL IG + + +VAFW L Sbjct: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593 >gi|7662470 neuroligin 1 [Homo sapiens] Length = 823 Score = 284 bits (727), Expect = 1e-76 Identities = 192/573 (33%), Positives = 284/573 (49%), Gaps = 62/573 (10%) Query: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83 P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112 Query: 84 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 133 + P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++ Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172 Query: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193 PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L Sbjct: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232 Query: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 244 D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA Sbjct: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292 Query: 245 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 304 I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++ Sbjct: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348 Query: 305 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 364 P G VIDG ++ P+ L + F M+G+N+ E G + Sbjct: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE-GLKFVENI 399 Query: 365 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDL 421 + D A+S + K+++ E + Y D + ++ L L Sbjct: 400 VDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLAL 459 Query: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481 D + P+V A H + G+PTY Y F + +D P HGDE+ V G P Sbjct: 460 FTDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPM 517 Query: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519 + S+ ++ LS +VM +W NFA+ G+PN + +P W Sbjct: 518 IGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWT 576 Query: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551 Y+QK+ YL IG + + + +V W L Sbjct: 577 RYSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609 >gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sapiens] Length = 614 Score = 250 bits (639), Expect = 2e-66 Identities = 188/574 (32%), Positives = 288/574 (50%), Gaps = 43/574 (7%) Query: 3 LRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLG 62 L +L L G + +V G++ G + L+ PV+ FLGIPFA+PP+G Sbjct: 17 LLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMG 74 Query: 63 PLRFTPPQPAEPWSFVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLY 119 P RF PP+P +PWS V +AT++ +C Q G +E++ +E LSEDCLY Sbjct: 75 PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLY 129 Query: 120 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWG 177 LN++TP + PV+VWI+GGG GA+S YDG L E V+V++ YR+G +G Sbjct: 130 LNVWTPYP-RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFG 188 Query: 178 FFST-GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPL 236 F + G + GN G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP Sbjct: 189 FLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPP 248 Query: 237 AKNLFHRAISESGVALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKT 291 ++ LFHRA+ +SG V G+ + A Q+A GC +V CLR + Sbjct: 249 SRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRP 308 Query: 292 EEELLETTLKMKFLSLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 349 + L+ + P+ES + V+DG L TPE L +FH + +V Sbjct: 309 AQVLVNHEWHVL---------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLV 359 Query: 350 GINKQEFGWLIPMQLMSYPL-SEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGG 407 G+ K E + + + +E + + ++ + P V +A E + +L Sbjct: 360 GVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-H 418 Query: 408 TDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIG 467 +D + ++ D++ D P +A GA Y Y F++R S S P + Sbjct: 419 PEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGV 476 Query: 468 DHGDELFSVFGAPF--LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYN 522 HG E+ +FG P + +EE+I ++ +M++WANFAR G+PN P WP Y Sbjct: 477 PHGYEIEFIFGIPLDPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYT 535 Query: 523 Q-KEGYLQIGAN-TQAAQKLKDKEVAFWTNLFAK 554 + Y+ + + + L+ + AFW K Sbjct: 536 AGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPK 569 >gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sapiens] Length = 617 Score = 250 bits (639), Expect = 2e-66 Identities = 188/574 (32%), Positives = 288/574 (50%), Gaps = 43/574 (7%) Query: 3 LRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLG 62 L +L L G + +V G++ G + L+ PV+ FLGIPFA+PP+G Sbjct: 17 LLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMG 74 Query: 63 PLRFTPPQPAEPWSFVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLY 119 P RF PP+P +PWS V +AT++ +C Q G +E++ +E LSEDCLY Sbjct: 75 PRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLY 129 Query: 120 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWG 177 LN++TP + PV+VWI+GGG GA+S YDG L E V+V++ YR+G +G Sbjct: 130 LNVWTPYP-RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFG 188 Query: 178 FFST-GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPL 236 F + G + GN G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP Sbjct: 189 FLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPP 248 Query: 237 AKNLFHRAISESGVALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKT 291 ++ LFHRA+ +SG V G+ + A Q+A GC +V CLR + Sbjct: 249 SRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRP 308 Query: 292 EEELLETTLKMKFLSLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 349 + L+ + P+ES + V+DG L TPE L +FH + +V Sbjct: 309 AQVLVNHEWHVL---------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLV 359 Query: 350 GINKQEFGWLIPMQLMSYPL-SEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGG 407 G+ K E + + + +E + + ++ + P V +A E + +L Sbjct: 360 GVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-H 418 Query: 408 TDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIG 467 +D + ++ D++ D P +A GA Y Y F++R S S P + Sbjct: 419 PEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGV 476 Query: 468 DHGDELFSVFGAPF--LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYN 522 HG E+ +FG P + +EE+I ++ +M++WANFAR G+PN P WP Y Sbjct: 477 PHGYEIEFIFGIPLDPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYT 535 Query: 523 Q-KEGYLQIGAN-TQAAQKLKDKEVAFWTNLFAK 554 + Y+ + + + L+ + AFW K Sbjct: 536 AGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPK 569 >gi|4557351 butyrylcholinesterase precursor [Homo sapiens] Length = 602 Score = 249 bits (637), Expect = 4e-66 Identities = 192/553 (34%), Positives = 273/553 (49%), Gaps = 41/553 (7%) Query: 20 HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 79 H ++ T +GKV G ++L F V FLGIP+A+PPLG LRF PQ WS + Sbjct: 27 HTEDDIIIATKNGKVRG--MNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIW 84 Query: 80 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 139 NAT Y C Q+ Q + N LSEDCLYLN++ PA K V++W Sbjct: 85 NATKYANSCCQN--IDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAP--KPKNATVLIW 140 Query: 140 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNWGHLDQV 196 I+GGG G +S YDG LA E V+VV++ YR+G GF + G+ + GN G DQ Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200 Query: 197 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV-----A 251 AL+WVQ NIA+FGGNP SVT+FGESAG SVS+ +LSP + +LF RAI +SG A Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260 Query: 252 LTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQG 311 +TS+ + LA+ GC ++ CLR K +E+L L F+ G Sbjct: 261 VTSLYEARNRTLNLAK----LTGCSRENETEIIKCLRNKDPQEIL---LNEAFVV--PYG 311 Query: 312 DPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSE 371 P G +DG L P+ L F +VG+NK E + + Sbjct: 312 TPLSVN--FGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDN 369 Query: 372 GQ-LDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKK--KDLFLDLIADVMF 427 + +K L +P V KE I Y DD + ++ D++ D F Sbjct: 370 NSIITRKEFQEGLKIFFPGVSEFGKESI---LFHYTDWVDDQRPENYREALGDVVGDYNF 426 Query: 428 GVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMK-PKTVIGDHGDELFSVFGAPF-LKEG 485 P++ + + G + Y F++R SS + P+ + HG E+ VFG P ++ Sbjct: 427 ICPALEFTKKFSEWGNNAFFYYFEHR---SSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483 Query: 486 ASEEEIRLSKMVMKFWANFARNGNPN--GEGLPHWPEYNQKE-GYLQIGA-NTQAAQKLK 541 ++ E LS+ ++K WANFA+ GNPN WP + E YL + +T+ KL+ Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLR 543 Query: 542 DKEVAFWTNLFAK 554 ++ FWT+ F K Sbjct: 544 AQQCRFWTSFFPK 556 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 233 bits (595), Expect = 3e-61 Identities = 189/571 (33%), Positives = 267/571 (46%), Gaps = 62/571 (10%) Query: 8 LATLSASAAWA-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 66 L L + WA + V T G V G L V IF GIPFA P Sbjct: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65 Query: 67 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 121 PQP W A ++ C TQD G EDCLYLN Sbjct: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107 Query: 122 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 172 I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR Sbjct: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167 Query: 173 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 232 +G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+ Sbjct: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227 Query: 233 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 290 LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+ Sbjct: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283 Query: 291 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 350 T+ L K+ L+ P VIDG + P L A N + Y+ G Sbjct: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338 Query: 351 INKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI--AKELIPEATEKYLGGT 408 N + + + + ++ ++ L+ + + AK TE + Sbjct: 339 TNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDP 398 Query: 409 DDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPKTVI 466 KKK + +D DV+F VP+ I HR A TY Y F + PS + PK V Sbjct: 399 SQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPKWVG 455 Query: 467 GDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWPEY- 521 DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW Y Sbjct: 456 ADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT 515 Query: 522 NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 549 + GYL+I ++ + L+ + +WT Sbjct: 516 TENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546 >gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 195 bits (495), Expect = 1e-49 Identities = 116/301 (38%), Positives = 170/301 (56%), Gaps = 25/301 (8%) Query: 142 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 201 GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 202 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 261 VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAI--ILYLKAH 137 Query: 262 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 318 +E + + A G + S + CLR K+ +ELL + K K + Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185 Query: 319 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKT 378 V+DG P +L +++ F +P ++G+N E G+ +PM+ LS ++ Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS--NKSL 240 Query: 379 AMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNH 438 A+ L + ++ I + +Y + +D LDL+ DV F +P +I AR H Sbjct: 241 ALCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYH 297 Query: 439 R 439 R Sbjct: 298 R 298 >gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 327 Score = 194 bits (493), Expect = 2e-49 Identities = 115/301 (38%), Positives = 170/301 (56%), Gaps = 25/301 (8%) Query: 142 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 201 GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79 Query: 202 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 261 VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAI--ILYLKAH 137 Query: 262 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 318 +E + + A G + S + CLR K+ +ELL + K K + Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185 Query: 319 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKT 378 V+DG P +L +++ F +P ++G+N E G+ +PM+ LS ++ Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS--NKSL 240 Query: 379 AMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNH 438 A+ L + ++ I + +Y + +D LDL+ DV F +P +I A+ H Sbjct: 241 ALCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYH 297 Query: 439 R 439 R Sbjct: 298 R 298 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 155 bits (392), Expect = 9e-38 Identities = 157/554 (28%), Positives = 241/554 (43%), Gaps = 57/554 (10%) Query: 22 SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 79 S P V + HG++LG+ +++ + V FLG+P+A PPL RF P+P W+ Sbjct: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255 Query: 80 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 139 +A+ C Q R P +SEDCLYLN++ P ++ V+V+ Sbjct: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301 Query: 140 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197 H + DG LAA N++VVT YR+G++GF S+G GNWG LDQVA Sbjct: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361 Query: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 254 AL WVQ +I FGG+P V++ + G + S+ +L+ A N LF RA+ G AL+ + Sbjct: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421 Query: 255 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 314 ++ + A +A C ++S +V CLRQK L + K+ +S Sbjct: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477 Query: 315 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 374 G VIDG L + P + V ++G ++ + + + S G+ Sbjct: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRT 2533 Query: 375 DQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVPS 431 KTA L S + AT Y TDD + D P Sbjct: 2534 SSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPI 2593 Query: 432 VIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA-S 487 + +A + A +MY S + D F++ G PF EG S Sbjct: 2594 IDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQFS 2645 Query: 488 EEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANTQ 535 EE LS +M+++++F R+GNPN +P WP++ + E Y + Sbjct: 2646 LEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLP 2705 Query: 536 AAQKLKDKEVAFWT 549 Q LK + +FW+ Sbjct: 2706 NRQGLKKADCSFWS 2719 >gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] Length = 131 Score = 111 bits (277), Expect = 2e-24 Identities = 51/90 (56%), Positives = 67/90 (74%) Query: 136 VMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQ 195 V++W GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQ Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79 Query: 196 VAALRWVQDNIASFGGNPGSVTIFGESAGG 225 VAAL WVQ NI FGG+P SVTIF + G Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109 >gi|68299767 arylacetamide deacetylase [Homo sapiens] Length = 399 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%) Query: 118 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 173 + + +Y P ++ R + +IHGGG VG+A S YD L+ A + VVV+ YRL Sbjct: 89 ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147 Query: 174 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 225 F E D ALRW + +A +G NP + I G+SAGG Sbjct: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192 >gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sapiens] Length = 440 Score = 38.5 bits (88), Expect = 0.017 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 15/101 (14%) Query: 137 MVWIHGGGLMVGAAST--YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGH 192 +V+IHGGG + +A YD L A+A N V+V+I+YRL +F Sbjct: 141 VVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH-------- 192 Query: 193 LDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 231 D V A ++ + + + +PG + I G+SAGG + L Sbjct: 193 -DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 232 >gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sapiens] Length = 448 Score = 37.4 bits (85), Expect = 0.037 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 23/109 (21%) Query: 137 MVWIHGGGLMVGAAST----------YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDE 184 +V+IHGGG + +AS YD L A+A N V+V+I+YRL +F Sbjct: 141 VVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH 200 Query: 185 HSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 231 D V A ++ + + + +PG + I G+SAGG + L Sbjct: 201 ---------DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 240 >gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] Length = 407 Score = 35.0 bits (79), Expect = 0.18 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%) Query: 137 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 194 +++ HGG + G+ Y GL LA V++ I YR D HS + D Sbjct: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165 Query: 195 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 231 + A + ++G +P V + GES GG +V+ + Sbjct: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 33.1 bits (74), Expect = 0.70 Identities = 14/25 (56%), Positives = 16/25 (64%) Query: 47 PVAIFLGIPFAKPPLGPLRFTPPQP 71 P +F G PF +PPLGPL PP P Sbjct: 275 PPVLFPGQPFGQPPLGPLPPGPPPP 299 >gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] Length = 401 Score = 32.7 bits (73), Expect = 0.92 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 16/112 (14%) Query: 120 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS--TYDGLA--LAAHENVVVVTIQYRLGI 175 + +Y P ++ R V ++ HGGG G++ +D L A + VVV + YRL Sbjct: 91 VRLYLPKRKSETRRRAV-IYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAP 149 Query: 176 WGFFSTGDEHSRGNWGHLDQVAALRW--VQDNIASFGGNPGSVTIFGESAGG 225 F E D +AA+++ ++ + +G +P + I G+S+GG Sbjct: 150 QHHFPAQFE---------DGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGG 192 >gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 32.0 bits (71), Expect = 1.6 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 9/66 (13%) Query: 7 ILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSL---------EGFAQPVAIFLGIPFA 57 ++A + A HP PPV T+ G LG SL + QPV + G P Sbjct: 497 VIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGM 556 Query: 58 KPPLGP 63 PP P Sbjct: 557 APPPAP 562 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,977,620 Number of Sequences: 37866 Number of extensions: 1079779 Number of successful extensions: 2756 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 2611 Number of HSP's gapped (non-prelim): 46 length of query: 568 length of database: 18,247,518 effective HSP length: 108 effective length of query: 460 effective length of database: 14,157,990 effective search space: 6512675400 effective search space used: 6512675400 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.