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Search of human proteins with 68508957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68508957 carboxylesterase 1 isoform c precursor [Homo
sapiens]
(566 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 1150 0.0
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 1145 0.0
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 1140 0.0
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 475 e-134
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 459 e-129
gi|33563374 carboxylesterase 3 [Homo sapiens] 451 e-127
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 431 e-120
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 394 e-110
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 366 e-101
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 293 4e-79
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 293 4e-79
gi|51593088 neuroligin 3 [Homo sapiens] 292 5e-79
gi|30840978 neuroligin 2 [Homo sapiens] 290 3e-78
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 286 5e-77
gi|7662470 neuroligin 1 [Homo sapiens] 286 5e-77
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 249 5e-66
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 247 2e-65
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 247 2e-65
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 236 5e-62
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 196 5e-50
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 195 8e-50
gi|55770862 thyroglobulin [Homo sapiens] 155 9e-38
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 111 2e-24
gi|68299767 arylacetamide deacetylase [Homo sapiens] 42 0.001
gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap... 39 0.017
gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa... 37 0.037
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 35 0.18
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 33 0.70
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 33 0.91
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 31 2.7
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 1150 bits (2974), Expect = 0.0
Identities = 566/566 (100%), Positives = 566/566 (100%)
Query: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL
Sbjct: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
Query: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN
Sbjct: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST
Sbjct: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
Query: 361 MLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLI 420
MLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLI
Sbjct: 361 MLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLI 420
Query: 421 ADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFL 480
ADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFL
Sbjct: 421 ADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFL 480
Query: 481 KEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKD 540
KEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKD
Sbjct: 481 KEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKD 540
Query: 541 KEVAFWTNLFAKKAVEKPPQTEHIEL 566
KEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 541 KEVAFWTNLFAKKAVEKPPQTEHIEL 566
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 1145 bits (2962), Expect = 0.0
Identities = 566/567 (99%), Positives = 566/567 (99%), Gaps = 1/567 (0%)
Query: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL
Sbjct: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
Query: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN
Sbjct: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST
Sbjct: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
Query: 361 M-LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 419
M LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL
Sbjct: 361 MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
Query: 420 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 479
IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF
Sbjct: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
Query: 480 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 539
LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK
Sbjct: 481 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 540
Query: 540 DKEVAFWTNLFAKKAVEKPPQTEHIEL 566
DKEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 541 DKEVAFWTNLFAKKAVEKPPQTEHIEL 567
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 1140 bits (2950), Expect = 0.0
Identities = 566/568 (99%), Positives = 566/568 (99%), Gaps = 2/568 (0%)
Query: 1 MWLRAFILATLSASAAW-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 59
MWLRAFILATLSASAAW GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP
Sbjct: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60
Query: 60 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 119
LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL
Sbjct: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120
Query: 120 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 179
NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS
Sbjct: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180
Query: 180 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 239
TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL
Sbjct: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240
Query: 240 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 299
FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL
Sbjct: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300
Query: 300 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 359
KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI
Sbjct: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360
Query: 360 PM-LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 418
PM LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
Sbjct: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420
Query: 419 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 478
LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP
Sbjct: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480
Query: 479 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 538
FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL
Sbjct: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540
Query: 539 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 566
KDKEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 475 bits (1222), Expect = e-134
Identities = 260/556 (46%), Positives = 350/556 (62%), Gaps = 29/556 (5%)
Query: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77
G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V
Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149
Query: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136
++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM
Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA
Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255
ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327
Query: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315
DV ++ +A + C S +V CLR K++EE+L K
Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372
Query: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQK 375
++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP +M ++ ++D++
Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDRE 430
Query: 376 TAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARN 435
+ + L K L+ + E+Y+G D + F +++AD MF +P++ VA +
Sbjct: 431 ASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA-H 489
Query: 436 HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDEL----FSVFGAPFLKEGASEEEIRL 491
+ + AP Y YEFQ++PS+ +++P + DHGDEL S FG ++K +EEE +L
Sbjct: 490 FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIK--FTEEEEQL 547
Query: 492 SKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFA 551
S+ +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW
Sbjct: 548 SRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALP 607
Query: 552 KKAVE-KPPQTEHIEL 566
+K E + P+ H EL
Sbjct: 608 QKIQELEEPEERHTEL 623
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 459 bits (1180), Expect = e-129
Identities = 252/552 (45%), Positives = 340/552 (61%), Gaps = 37/552 (6%)
Query: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77
G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V
Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149
Query: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136
++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM
Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA
Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255
ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327
Query: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315
DV ++ +A + C S +V CLR K++EE+L K
Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372
Query: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQK 375
++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP +M ++ ++D++
Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDRE 430
Query: 376 TAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARN 435
+ + L K L+ + E+Y+G D + F +++AD MF +P++ VA +
Sbjct: 431 ASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA-H 489
Query: 436 HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMV 495
+ + AP Y YEFQ++PS+ +++P + DH +EEE +LS+ +
Sbjct: 490 FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRKM 535
Query: 496 MKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAV 555
MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K
Sbjct: 536 MKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQ 595
Query: 556 E-KPPQTEHIEL 566
E + P+ H EL
Sbjct: 596 ELEEPEERHTEL 607
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 451 bits (1160), Expect = e-127
Identities = 242/548 (44%), Positives = 342/548 (62%), Gaps = 25/548 (4%)
Query: 14 SAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEP 73
+ A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P PA+P
Sbjct: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83
Query: 74 WSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRL 133
W V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ +
Sbjct: 84 WEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPAGSGR 141
Query: 134 PVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN G LD
Sbjct: 142 PVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLD 201
Query: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTS 253
VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV T
Sbjct: 202 VVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTP 261
Query: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313
++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K
Sbjct: 262 GII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK----------- 308
Query: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLD 373
+ +DG + K+P+EL E+ FH+VP+++G+N EF WLIP + Q+
Sbjct: 309 --NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMS 366
Query: 374 QKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVA 433
++ +++ + + E++P ++YLG D K F + + DV VP+V +
Sbjct: 367 REDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFS 426
Query: 434 RNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE--------GAS 485
R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL + A+
Sbjct: 427 RYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEAT 486
Query: 486 EEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAF 545
EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A QK ++ + F
Sbjct: 487 EEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQF 546
Query: 546 WTNLFAKK 553
W+ K
Sbjct: 547 WSETLPSK 554
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 431 bits (1107), Expect = e-120
Identities = 241/545 (44%), Positives = 322/545 (59%), Gaps = 32/545 (5%)
Query: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
Query: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
Query: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
Query: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSE 369
V+DG P +L +++ F +P ++G+N E G+L+PM + +
Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 370 GQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPS 429
G ++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP+
Sbjct: 361 GS-NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPA 416
Query: 430 VIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK------EG 483
+I AR HRDAGAP Y YEF++RP D KP V DH DE+ VFG FLK EG
Sbjct: 417 LITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEG 476
Query: 484 ASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEV 543
A+EEE LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V
Sbjct: 477 ATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRV 536
Query: 544 AFWTN 548
FWT+
Sbjct: 537 DFWTS 541
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 394 bits (1013), Expect = e-110
Identities = 226/564 (40%), Positives = 318/564 (56%), Gaps = 81/564 (14%)
Query: 2 WLRAFILAT-LSASAAWG--HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKP 58
W+ + L L A A G H P VV T +G + GK + + P+ +FLG+PF++P
Sbjct: 3 WILCWSLTLCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRP 59
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY 118
PLG LRF PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLY
Sbjct: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLY 118
Query: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFF 178
LN+Y PA +LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF
Sbjct: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFL 178
Query: 179 STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN 238
ST D H+RGNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA
Sbjct: 179 STDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASG 238
Query: 239 LFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETT 298
LFHRAIS+SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ +
Sbjct: 239 LFHRAISQSGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVS 297
Query: 299 LKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL 358
KM+FL L+ Q DP E + V+DG+++ P L + +VPY++G+N EF WL
Sbjct: 298 NKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWL 357
Query: 359 IPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDLF 416
+P I KE +P E+YL + D ++
Sbjct: 358 LP---------------------------YNITKEQVPLVVEEYLDNVNEHDWKMLRNRM 390
Query: 417 LDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFG 476
+D++ D F ++ A HR G
Sbjct: 391 MDIVQDATFVYATLQTAHYHR--------------------------------------G 412
Query: 477 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQ 536
KE A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+
Sbjct: 413 LSMGKEKA------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGM 466
Query: 537 KLKDKEVAFWTNLFAKKAVEKPPQ 560
KLK+K++AFW +L+ + EK Q
Sbjct: 467 KLKEKKMAFWMSLYQSQRPEKQRQ 490
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 366 bits (940), Expect = e-101
Identities = 216/539 (40%), Positives = 294/539 (54%), Gaps = 70/539 (12%)
Query: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
Query: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
Query: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
Query: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSE 369
V+DG P +L +++ F +P ++G+N E G+L+PM + +
Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 370 GQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPS 429
G ++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP+
Sbjct: 361 GS-NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPA 416
Query: 430 VIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEI 489
+I AR HR EGA+EEE
Sbjct: 417 LITARYHR--------------------------------------------EGATEEEK 432
Query: 490 RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 548
LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+
Sbjct: 433 LLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 293 bits (749), Expect = 4e-79
Identities = 199/588 (33%), Positives = 294/588 (50%), Gaps = 60/588 (10%)
Query: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
Query: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
Query: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
Query: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
Query: 349 GINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYL----G 404
G+N+ E + ++ D ++S + K+ + E T K++
Sbjct: 370 GVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE-TIKFMYTDWA 428
Query: 405 GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVI 464
++ ++ + L D + P+V A H G+PTY Y F + S+MKP
Sbjct: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWAD 486
Query: 465 GDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH--- 515
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTK 545
Query: 516 -------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
W +YN K+ YL IG + + +VAFW L
Sbjct: 546 FIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 293 bits (749), Expect = 4e-79
Identities = 199/588 (33%), Positives = 294/588 (50%), Gaps = 60/588 (10%)
Query: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
Query: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
Query: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
Query: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
Query: 349 GINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYL----G 404
G+N+ E + ++ D ++S + K+ + E T K++
Sbjct: 370 GVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE-TIKFMYTDWA 428
Query: 405 GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVI 464
++ ++ + L D + P+V A H G+PTY Y F + S+MKP
Sbjct: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWAD 486
Query: 465 GDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH--- 515
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTK 545
Query: 516 -------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
W +YN K+ YL IG + + +VAFW L
Sbjct: 546 FIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 292 bits (748), Expect = 5e-79
Identities = 199/590 (33%), Positives = 286/590 (48%), Gaps = 88/590 (14%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
P V+T GK+ G V L PV +LG+P+A PP+G RF PP+P WS ++NAT
Sbjct: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 83 YPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SEDCLYLNIYTPA----------- 125
+PP+C Q+ +L FT + + + +EDCLYLN+Y P
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
Query: 126 -----------DLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174
D+ PVMV+IHGG M G + DG LA++ NV+V+T+ YR+G+
Sbjct: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
Query: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234
GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P +T+FG G VS+L LS
Sbjct: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
Query: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294
++ LF RAI +SG AL+S V VK +A GC + MV CLRQK+ +EL
Sbjct: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKVGCNVLDTVDMVDCLRQKSAKEL 340
Query: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354
+E ++ P G VIDG ++ PE L + F M+G+N+ E
Sbjct: 341 VEQDIQ-----------PARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGE 389
Query: 355 FGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL--- 403
EG +D + +S Y + L PE T K++
Sbjct: 390 ---------GLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
Query: 404 -GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKT 462
D+ ++ + L D + PSV+ A H G+PTY Y F + S MKP
Sbjct: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHH--CQSLMKPAW 498
Query: 463 VIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH- 515
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 499 SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQD 557
Query: 516 ---------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
W +YN ++ YL IG + + +VAFW +L
Sbjct: 558 TKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL 607
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 290 bits (741), Expect = 3e-78
Identities = 203/628 (32%), Positives = 297/628 (47%), Gaps = 103/628 (16%)
Query: 1 MWLRAFILATLSASA------AWGHPSSP------------PVVDTVHGKVLGKFVSLEG 42
MWL A L L+ + G P P PVV+T +G+V G L
Sbjct: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
Query: 43 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 98
PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L
Sbjct: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
Query: 99 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 136
FT+ E + SEDCLYLN+Y P + LTKK + PVM
Sbjct: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
+++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+
Sbjct: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 256
ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V
Sbjct: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
Query: 257 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 316
+K +A GC SA V CLR+K EL++ ++ P
Sbjct: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348
Query: 317 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKT 376
G V+DG ++ PE L + F ++G+N+ E E + +
Sbjct: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGE---------GLKFVEDSAESED 399
Query: 377 AMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDLIADVM 424
+S + + L PE T K++ D+ ++ L L D
Sbjct: 400 GVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQ 459
Query: 425 FGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE-- 482
+ P+V A+ H D +P Y Y F + ++ +P+ HGDEL VFG P +
Sbjct: 460 WVAPAVATAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATD 517
Query: 483 ----GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQK 522
S+ ++ LS +VM +W NFA+ G+PN + +P W ++N K
Sbjct: 518 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSK 576
Query: 523 E-GYLQIGANTQAAQKLKDKEVAFWTNL 549
E YL IG + + +VAFW L
Sbjct: 577 EKQYLHIGLKPRVRDNYRANKVAFWLEL 604
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 286 bits (731), Expect = 5e-77
Identities = 190/564 (33%), Positives = 285/564 (50%), Gaps = 54/564 (9%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT
Sbjct: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
Query: 83 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 132
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N +
Sbjct: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L
Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
Query: 253 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 312
S V K +A GC + MV CL+ K +EL++ T+ P
Sbjct: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333
Query: 313 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQL 372
G VIDG ++ P+ L + F M+G+N+ E + ++
Sbjct: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPN 393
Query: 373 DQKTAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVP 428
D ++S + K+ + E T K++ ++ ++ + L D + P
Sbjct: 394 DFDFSVSNFVDNLYGYPEGKDTLRE-TIKFMYTDWADKENPETRRKTLVALFTDHQWVAP 452
Query: 429 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------ 482
+V A H G+PTY Y F + S+MKP HGDE+ VFG P +
Sbjct: 453 AVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSC 510
Query: 483 GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKEG-Y 525
S+ ++ LS +VM +W NFA+ G+PN + +P W +YN K+ Y
Sbjct: 511 NFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLY 569
Query: 526 LQIGANTQAAQKLKDKEVAFWTNL 549
L IG + + +VAFW L
Sbjct: 570 LHIGLKPRVRDHYRATKVAFWLEL 593
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 286 bits (731), Expect = 5e-77
Identities = 191/572 (33%), Positives = 284/572 (49%), Gaps = 61/572 (10%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 83 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 132
+ P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L
Sbjct: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 243
D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA
Sbjct: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
Query: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++
Sbjct: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348
Query: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLM 363
P G VIDG ++ P+ L + F M+G+N+ E + ++
Sbjct: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV 400
Query: 364 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDLI 420
D A+S + K+++ E + Y D + ++ L L
Sbjct: 401 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF 460
Query: 421 ADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFL 480
D + P+V A H + G+PTY Y F + +D P HGDE+ V G P +
Sbjct: 461 TDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPMI 518
Query: 481 KE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPE 518
S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 519 GPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWTR 577
Query: 519 YNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
Y+QK+ YL IG + + + +V W L
Sbjct: 578 YSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 249 bits (636), Expect = 5e-66
Identities = 193/553 (34%), Positives = 275/553 (49%), Gaps = 42/553 (7%)
Query: 19 HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78
H ++ T +GKV G ++L F V FLGIP+A+PPLG LRF PQ WS +
Sbjct: 27 HTEDDIIIATKNGKVRG--MNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIW 84
Query: 79 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138
NAT Y C Q+ Q + N LSEDCLYLN++ PA K V++W
Sbjct: 85 NATKYANSCCQN--IDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAP--KPKNATVLIW 140
Query: 139 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNWGHLDQV 195
I+GGG G +S YDG LA E V+VV++ YR+G GF + G+ + GN G DQ
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200
Query: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV-----A 250
AL+WVQ NIA+FGGNP SVT+FGESAG SVS+ +LSP + +LF RAI +SG A
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260
Query: 251 LTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQG 310
+TS+ + LA+ GC ++ CLR K +E+L L F+ G
Sbjct: 261 VTSLYEARNRTLNLAK----LTGCSRENETEIIKCLRNKDPQEIL---LNEAFVV--PYG 311
Query: 311 DPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE-FGWLIPMLMSYPLSE 369
P G +DG L P+ L F +VG+NK E +L+ +
Sbjct: 312 TPLSVN--FGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDN 369
Query: 370 GQ-LDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKK--KDLFLDLIADVMF 425
+ +K L +P V KE I Y DD + ++ D++ D F
Sbjct: 370 NSIITRKEFQEGLKIFFPGVSEFGKESI---LFHYTDWVDDQRPENYREALGDVVGDYNF 426
Query: 426 GVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMK-PKTVIGDHGDELFSVFGAPF-LKEG 483
P++ + + G + Y F++R SS + P+ + HG E+ VFG P ++
Sbjct: 427 ICPALEFTKKFSEWGNNAFFYYFEHR---SSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483
Query: 484 ASEEEIRLSKMVMKFWANFARNGNPN--GEGLPHWPEYNQKE-GYLQIGA-NTQAAQKLK 539
++ E LS+ ++K WANFA+ GNPN WP + E YL + +T+ KL+
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLR 543
Query: 540 DKEVAFWTNLFAK 552
++ FWT+ F K
Sbjct: 544 AQQCRFWTSFFPK 556
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 247 bits (630), Expect = 2e-65
Identities = 187/562 (33%), Positives = 286/562 (50%), Gaps = 48/562 (8%)
Query: 16 AWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWS 75
A G + +V G++ G + L+ PV+ FLGIPFA+PP+GP RF PP+P +PWS
Sbjct: 31 AEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS 88
Query: 76 FVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
V +AT++ +C Q G +E++ +E LSEDCLYLN++TP +
Sbjct: 89 GVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLYLNVWTPYP-RPTSP 142
Query: 133 LPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNW 189
PV+VWI+GGG GA+S YDG L E V+V++ YR+G +GF + G + GN
Sbjct: 143 TPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNV 202
Query: 190 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 249
G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP ++ LFHRA+ +SG
Sbjct: 203 GLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262
Query: 250 ALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKTEEELLETTLKMKFL 304
V G+ + A Q+A GC +V CLR + + L+ +
Sbjct: 263 PNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVL-- 320
Query: 305 SLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPML 362
P+ES + V+DG L TPE L +FH + +VG+ K E + ++
Sbjct: 321 -------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYF--LV 371
Query: 363 MSYP----LSEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKKKDLFL 417
P +E + + ++ + P V +A E + +L +D + ++
Sbjct: 372 YGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-HPEDPARLREALS 430
Query: 418 DLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGA 477
D++ D P +A GA Y Y F++R S S P + HG E+ +FG
Sbjct: 431 DVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGI 488
Query: 478 PF--LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYNQ-KEGYLQIGAN 531
P + +EE+I ++ +M++WANFAR G+PN P WP Y + Y+ +
Sbjct: 489 PLDPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLR 547
Query: 532 -TQAAQKLKDKEVAFWTNLFAK 552
+ + L+ + AFW K
Sbjct: 548 PLEVRRGLRAQACAFWNRFLPK 569
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 247 bits (630), Expect = 2e-65
Identities = 187/562 (33%), Positives = 286/562 (50%), Gaps = 48/562 (8%)
Query: 16 AWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWS 75
A G + +V G++ G + L+ PV+ FLGIPFA+PP+GP RF PP+P +PWS
Sbjct: 31 AEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS 88
Query: 76 FVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
V +AT++ +C Q G +E++ +E LSEDCLYLN++TP +
Sbjct: 89 GVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLYLNVWTPYP-RPTSP 142
Query: 133 LPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNW 189
PV+VWI+GGG GA+S YDG L E V+V++ YR+G +GF + G + GN
Sbjct: 143 TPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNV 202
Query: 190 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 249
G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP ++ LFHRA+ +SG
Sbjct: 203 GLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262
Query: 250 ALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKTEEELLETTLKMKFL 304
V G+ + A Q+A GC +V CLR + + L+ +
Sbjct: 263 PNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVL-- 320
Query: 305 SLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPML 362
P+ES + V+DG L TPE L +FH + +VG+ K E + ++
Sbjct: 321 -------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYF--LV 371
Query: 363 MSYP----LSEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKKKDLFL 417
P +E + + ++ + P V +A E + +L +D + ++
Sbjct: 372 YGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-HPEDPARLREALS 430
Query: 418 DLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGA 477
D++ D P +A GA Y Y F++R S S P + HG E+ +FG
Sbjct: 431 DVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGI 488
Query: 478 PF--LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYNQ-KEGYLQIGAN 531
P + +EE+I ++ +M++WANFAR G+PN P WP Y + Y+ +
Sbjct: 489 PLDPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLR 547
Query: 532 -TQAAQKLKDKEVAFWTNLFAK 552
+ + L+ + AFW K
Sbjct: 548 PLEVRRGLRAQACAFWNRFLPK 569
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 236 bits (601), Expect = 5e-62
Identities = 193/574 (33%), Positives = 270/574 (47%), Gaps = 70/574 (12%)
Query: 8 LATLSASAAWGHPSSPPV--VDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
L L + W S+ + V T G V G L V IF GIPFA P
Sbjct: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65
Query: 66 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
PQP W A ++ C TQD G EDCLYLN
Sbjct: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107
Query: 121 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 171
I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR
Sbjct: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
Query: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
+G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+
Sbjct: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
Query: 232 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 289
LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+
Sbjct: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283
Query: 290 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 349
T+ L K+ L+ P VIDG + P L A N + Y+ G
Sbjct: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338
Query: 350 INKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCI------AKELIPEATEKYL 403
N + G + + +++G ++K +K I AK TE +
Sbjct: 339 TNNMD-GHIFASIDMPAINKG--NKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWA 395
Query: 404 GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPK 461
KKK + +D DV+F VP+ I HR A TY Y F + PS + PK
Sbjct: 396 QDPSQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPK 452
Query: 462 TVIGDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWP 517
V DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW
Sbjct: 453 WVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWE 512
Query: 518 EY-NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 547
Y + GYL+I ++ + L+ + +WT
Sbjct: 513 PYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 196 bits (498), Expect = 5e-50
Identities = 115/300 (38%), Positives = 170/300 (56%), Gaps = 24/300 (8%)
Query: 141 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 200
GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 260
VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAI--ILYLKAH 137
Query: 261 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 317
+E + + A G + S + CLR K+ +ELL + K K +
Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185
Query: 318 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTA 377
V+DG P +L +++ F +P ++G+N E G+ +PM + + G ++ A
Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS-NKSLA 241
Query: 378 MSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHR 437
+ L + ++ I + +Y + +D LDL+ DV F +P +I AR HR
Sbjct: 242 LCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYHR 298
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 195 bits (496), Expect = 8e-50
Identities = 114/300 (38%), Positives = 170/300 (56%), Gaps = 24/300 (8%)
Query: 141 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 200
GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 260
VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAI--ILYLKAH 137
Query: 261 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 317
+E + + A G + S + CLR K+ +ELL + K K +
Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185
Query: 318 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTA 377
V+DG P +L +++ F +P ++G+N E G+ +PM + + G ++ A
Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS-NKSLA 241
Query: 378 MSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHR 437
+ L + ++ I + +Y + +D LDL+ DV F +P +I A+ HR
Sbjct: 242 LCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYHR 298
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 155 bits (392), Expect = 9e-38
Identities = 159/555 (28%), Positives = 243/555 (43%), Gaps = 60/555 (10%)
Query: 21 SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78
S P V + HG++LG+ +++ + V FLG+P+A PPL RF P+P W+
Sbjct: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255
Query: 79 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138
+A+ C Q R P +SEDCLYLN++ P ++ V+V+
Sbjct: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301
Query: 139 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
H + DG LAA N++VVT YR+G++GF S+G GNWG LDQVA
Sbjct: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 253
AL WVQ +I FGG+P V++ + G + S+ +L+ A N LF RA+ G AL+ +
Sbjct: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
Query: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313
++ + A +A C ++S +V CLRQK L + K+ +S
Sbjct: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477
Query: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL--IPMLMSYPLSEGQ 371
G VIDG L + P + V ++G + Q+ G + + + S G+
Sbjct: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIG-SSQDDGLINRAKAVKQFEESRGR 2532
Query: 372 LDQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVP 428
KTA L S + AT Y TDD + D P
Sbjct: 2533 TSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICP 2592
Query: 429 SVIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA- 484
+ +A + A +MY S + D F++ G PF EG
Sbjct: 2593 IIDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQF 2644
Query: 485 SEEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANT 532
S EE LS +M+++++F R+GNPN +P WP++ + E Y +
Sbjct: 2645 SLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELL 2704
Query: 533 QAAQKLKDKEVAFWT 547
Q LK + +FW+
Sbjct: 2705 PNRQGLKKADCSFWS 2719
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 111 bits (277), Expect = 2e-24
Identities = 51/90 (56%), Positives = 67/90 (74%)
Query: 135 VMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQ 194
V++W GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 195 VAALRWVQDNIASFGGNPGSVTIFGESAGG 224
VAAL WVQ NI FGG+P SVTIF + G
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109
>gi|68299767 arylacetamide deacetylase [Homo sapiens]
Length = 399
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 117 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 172
+ + +Y P ++ R + +IHGGG VG+A S YD L+ A + VVV+ YRL
Sbjct: 89 ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
Query: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 224
F E D ALRW + +A +G NP + I G+SAGG
Sbjct: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
>gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo
sapiens]
Length = 440
Score = 38.5 bits (88), Expect = 0.017
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 15/101 (14%)
Query: 136 MVWIHGGGLMVGAAST--YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGH 191
+V+IHGGG + +A YD L A+A N V+V+I+YRL +F
Sbjct: 141 VVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH-------- 192
Query: 192 LDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 230
D V A ++ + + + +PG + I G+SAGG + L
Sbjct: 193 -DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 232
>gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo
sapiens]
Length = 448
Score = 37.4 bits (85), Expect = 0.037
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 23/109 (21%)
Query: 136 MVWIHGGGLMVGAAST----------YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDE 183
+V+IHGGG + +AS YD L A+A N V+V+I+YRL +F
Sbjct: 141 VVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH 200
Query: 184 HSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 230
D V A ++ + + + +PG + I G+SAGG + L
Sbjct: 201 ---------DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 240
>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
Length = 407
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 136 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
+++ HGG + G+ Y GL LA V++ I YR D HS + D
Sbjct: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165
Query: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 230
+ A + ++G +P V + GES GG +V+ +
Sbjct: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 33.1 bits (74), Expect = 0.70
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 46 PVAIFLGIPFAKPPLGPLRFTPPQP 70
P +F G PF +PPLGPL PP P
Sbjct: 275 PPVLFPGQPFGQPPLGPLPPGPPPP 299
>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
Length = 401
Score = 32.7 bits (73), Expect = 0.91
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 16/112 (14%)
Query: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS--TYDGLA--LAAHENVVVVTIQYRLGI 174
+ +Y P ++ R V ++ HGGG G++ +D L A + VVV + YRL
Sbjct: 91 VRLYLPKRKSETRRRAV-IYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAP 149
Query: 175 WGFFSTGDEHSRGNWGHLDQVAALRW--VQDNIASFGGNPGSVTIFGESAGG 224
F E D +AA+++ ++ + +G +P + I G+S+GG
Sbjct: 150 QHHFPAQFE---------DGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGG 192
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 31.2 bits (69), Expect = 2.7
Identities = 22/68 (32%), Positives = 25/68 (36%), Gaps = 9/68 (13%)
Query: 4 RAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSL---------EGFAQPVAIFLGIP 54
R I A HP PPV T+ G LG SL + QPV + G P
Sbjct: 495 RVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
Query: 55 FAKPPLGP 62
PP P
Sbjct: 555 GMAPPPAP 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,897,691
Number of Sequences: 37866
Number of extensions: 1079824
Number of successful extensions: 2768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2625
Number of HSP's gapped (non-prelim): 48
length of query: 566
length of database: 18,247,518
effective HSP length: 108
effective length of query: 458
effective length of database: 14,157,990
effective search space: 6484359420
effective search space used: 6484359420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.