BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|65506789 solute carrier family 26, member 10 [Homo sapiens] (563 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 1090 0.0 gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 297 2e-80 gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 297 2e-80 gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 279 6e-75 gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 279 6e-75 gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 279 6e-75 gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 279 6e-75 gi|4505697 pendrin [Homo sapiens] 276 4e-74 gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 260 3e-69 gi|45827802 prestin isoform c [Homo sapiens] 258 1e-68 gi|45827800 prestin isoform b [Homo sapiens] 258 1e-68 gi|39752683 prestin isoform a [Homo sapiens] 258 1e-68 gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 247 2e-65 gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 239 6e-63 gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 239 6e-63 gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 228 1e-59 gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 228 1e-59 gi|45827804 prestin isoform d [Homo sapiens] 166 7e-41 gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 157 3e-38 gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 132 6e-31 gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 91 2e-18 gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 80 5e-15 gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 67 4e-11 gi|93141208 SLAIN motif family, member 1 A [Homo sapiens] 30 4.5 gi|21389389 SLAIN motif family, member 1 B [Homo sapiens] 30 4.5 gi|164607124 Fanconi anemia, complementation group I isoform 1 [... 30 5.9 gi|82830440 Fanconi anemia, complementation group I isoform 2 [H... 30 5.9 gi|31881740 solute carrier family 12 (potassium/chloride transpo... 30 5.9 gi|33469987 asteroid homolog 1 [Homo sapiens] 30 5.9 gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 30 7.7 >gi|65506789 solute carrier family 26, member 10 [Homo sapiens] Length = 563 Score = 1090 bits (2818), Expect = 0.0 Identities = 563/563 (100%), Positives = 563/563 (100%) Query: 1 MRLDLASLMSAPKSLGSAFKSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSF 60 MRLDLASLMSAPKSLGSAFKSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSF Sbjct: 1 MRLDLASLMSAPKSLGSAFKSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSF 60 Query: 61 FPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLVGNLSGIEKEQLDAQRVGVAA 120 FPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLVGNLSGIEKEQLDAQRVGVAA Sbjct: 61 FPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLVGNLSGIEKEQLDAQRVGVAA 120 Query: 121 AVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGC 180 AVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGC Sbjct: 121 AVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGC 180 Query: 181 FSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLA 240 FSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLA Sbjct: 181 FSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLA 240 Query: 241 SVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASI 300 SVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASI Sbjct: 241 SVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASI 300 Query: 301 HADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTV 360 HADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTV Sbjct: 301 HADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTV 360 Query: 361 VLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQVPGLCILS 420 VLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQVPGLCILS Sbjct: 361 VLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQVPGLCILS 420 Query: 421 YPTPLYFGTRGQFRCNLEWHLGLGEGEKETSKPDGPMVAVAEPVRVVVLDFSGVTFADAA 480 YPTPLYFGTRGQFRCNLEWHLGLGEGEKETSKPDGPMVAVAEPVRVVVLDFSGVTFADAA Sbjct: 421 YPTPLYFGTRGQFRCNLEWHLGLGEGEKETSKPDGPMVAVAEPVRVVVLDFSGVTFADAA 480 Query: 481 GAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVTPDQLFVSVQDAAAY 540 GAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVTPDQLFVSVQDAAAY Sbjct: 481 GAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVTPDQLFVSVQDAAAY 540 Query: 541 ALGSLLRGSSTRSGSQEALGCGK 563 ALGSLLRGSSTRSGSQEALGCGK Sbjct: 541 ALGSLLRGSSTRSGSQEALGCGK 563 >gi|16306483 solute carrier family 26, member 7 isoform a [Homo sapiens] Length = 656 Score = 297 bits (760), Expect = 2e-80 Identities = 151/374 (40%), Positives = 236/374 (63%), Gaps = 5/374 (1%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+L+SV PVFGLY S FP +IY++ G G H++TGTFA+ SL++ +AVER+VP+ + Sbjct: 65 GLAFAVLSSVHPVFGLYGSLFPAIIYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQ 124 Query: 101 G-----NLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTS 155 N S + + QR+ VAAAV+F G + + MFVLQLG + ++EPV+ A+T+ Sbjct: 125 NLTTQSNTSVLGLSDFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTT 184 Query: 156 GAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPV 215 GAA HV+ SQ+ LLG+ +P G F A + + L +S LS+ +LV V Sbjct: 185 GAATHVVTSQVKYLLGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLV 244 Query: 216 KELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAE 275 KELN +F+ ++ +P ++VL++ AS C+ ++++ Y +++VG +P G P P P + Sbjct: 245 KELNEQFKRKIKVVLPVDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNI 304 Query: 276 LPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSA 335 L ++ ++ +ALV + S +LA A K+ Y+ID NQEFLAHG SN++SS F C P++A Sbjct: 305 LSAVITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAA 364 Query: 336 TLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQM 395 + T L G KTQ+A L SC VL V+ +GP Y+LP VLA I + ++ + Q Sbjct: 365 AMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQF 424 Query: 396 QELPQLWHISRVDF 409 ++L + W++ ++D+ Sbjct: 425 RDLKKYWNVDKIDW 438 Score = 35.0 bits (79), Expect = 0.18 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVT 526 ++LD SG TF D +G +V+V C+ + +LLA C A + +T G LD Sbjct: 572 LILDCSGFTFFDYSGVSMLVEVY----MDCKGRSVDVLLAHCTASLIKAMTYYGNLDSEK 627 Query: 527 PDQLFVSVQDAAAY 540 P F SV A ++ Sbjct: 628 P-IFFESVSAAISH 640 >gi|20336282 solute carrier family 26, member 7 isoform b [Homo sapiens] Length = 663 Score = 297 bits (760), Expect = 2e-80 Identities = 151/374 (40%), Positives = 236/374 (63%), Gaps = 5/374 (1%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+L+SV PVFGLY S FP +IY++ G G H++TGTFA+ SL++ +AVER+VP+ + Sbjct: 65 GLAFAVLSSVHPVFGLYGSLFPAIIYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQ 124 Query: 101 G-----NLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTS 155 N S + + QR+ VAAAV+F G + + MFVLQLG + ++EPV+ A+T+ Sbjct: 125 NLTTQSNTSVLGLSDFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTT 184 Query: 156 GAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPV 215 GAA HV+ SQ+ LLG+ +P G F A + + L +S LS+ +LV V Sbjct: 185 GAATHVVTSQVKYLLGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLV 244 Query: 216 KELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAE 275 KELN +F+ ++ +P ++VL++ AS C+ ++++ Y +++VG +P G P P P + Sbjct: 245 KELNEQFKRKIKVVLPVDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNI 304 Query: 276 LPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSA 335 L ++ ++ +ALV + S +LA A K+ Y+ID NQEFLAHG SN++SS F C P++A Sbjct: 305 LSAVITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAA 364 Query: 336 TLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQM 395 + T L G KTQ+A L SC VL V+ +GP Y+LP VLA I + ++ + Q Sbjct: 365 AMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQF 424 Query: 396 QELPQLWHISRVDF 409 ++L + W++ ++D+ Sbjct: 425 RDLKKYWNVDKIDW 438 Score = 35.0 bits (79), Expect = 0.18 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLDRVT 526 ++LD SG TF D +G +V+V C+ + +LLA C A + +T G LD Sbjct: 572 LILDCSGFTFFDYSGVSMLVEVY----MDCKGRSVDVLLAHCTASLIKAMTYYGNLDSEK 627 Query: 527 PDQLFVSVQDAAAY 540 P F SV A ++ Sbjct: 628 P-IFFESVSAAISH 640 >gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo sapiens] Length = 738 Score = 279 bits (713), Expect = 6e-75 Identities = 147/371 (39%), Positives = 230/371 (61%), Gaps = 2/371 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+A+ALLA +PPVFGLY+SF+PV IY L GT RH+S GTFA++S+M GS E L P+ L Sbjct: 87 GLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL- 145 Query: 101 GNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALH 160 N S I + DA RV VA+ ++ G +G+ ++ G + T+LSEP+V+ T+ AA+ Sbjct: 146 -NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 204 Query: 161 VLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNV 220 V +SQL + GL L G SL T+ + LP+S + +A++ +LV VK LN Sbjct: 205 VFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLND 264 Query: 221 RFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRIL 280 + + +LP PIPGE++ ++ A+ + + + R++V +VG +P G P+ PN +++ Sbjct: 265 KLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLV 324 Query: 281 ADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATT 340 + IA+V FA++ SL I A ++ Y +DSNQE +A G SNLI +F CFP S +++ + Sbjct: 325 GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRS 384 Query: 341 NLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQ 400 + GG +Q+AG S +L +++ LG F+ LPKAVLA I I +++ + Q+ ++ Sbjct: 385 LVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRS 444 Query: 401 LWHISRVDFLL 411 LW +R D L+ Sbjct: 445 LWKANRADLLI 455 >gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo sapiens] Length = 740 Score = 279 bits (713), Expect = 6e-75 Identities = 147/371 (39%), Positives = 230/371 (61%), Gaps = 2/371 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+A+ALLA +PPVFGLY+SF+PV IY L GT RH+S GTFA++S+M GS E L P+ L Sbjct: 108 GLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL- 166 Query: 101 GNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALH 160 N S I + DA RV VA+ ++ G +G+ ++ G + T+LSEP+V+ T+ AA+ Sbjct: 167 -NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 225 Query: 161 VLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNV 220 V +SQL + GL L G SL T+ + LP+S + +A++ +LV VK LN Sbjct: 226 VFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLND 285 Query: 221 RFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRIL 280 + + +LP PIPGE++ ++ A+ + + + R++V +VG +P G P+ PN +++ Sbjct: 286 KLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLV 345 Query: 281 ADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATT 340 + IA+V FA++ SL I A ++ Y +DSNQE +A G SNLI +F CFP S +++ + Sbjct: 346 GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRS 405 Query: 341 NLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQ 400 + GG +Q+AG S +L +++ LG F+ LPKAVLA I I +++ + Q+ ++ Sbjct: 406 LVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRS 465 Query: 401 LWHISRVDFLL 411 LW +R D L+ Sbjct: 466 LWKANRADLLI 476 >gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo sapiens] Length = 758 Score = 279 bits (713), Expect = 6e-75 Identities = 147/371 (39%), Positives = 230/371 (61%), Gaps = 2/371 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+A+ALLA +PPVFGLY+SF+PV IY L GT RH+S GTFA++S+M GS E L P+ L Sbjct: 108 GLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL- 166 Query: 101 GNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALH 160 N S I + DA RV VA+ ++ G +G+ ++ G + T+LSEP+V+ T+ AA+ Sbjct: 167 -NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 225 Query: 161 VLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNV 220 V +SQL + GL L G SL T+ + LP+S + +A++ +LV VK LN Sbjct: 226 VFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLND 285 Query: 221 RFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRIL 280 + + +LP PIPGE++ ++ A+ + + + R++V +VG +P G P+ PN +++ Sbjct: 286 KLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLV 345 Query: 281 ADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATT 340 + IA+V FA++ SL I A ++ Y +DSNQE +A G SNLI +F CFP S +++ + Sbjct: 346 GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRS 405 Query: 341 NLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQ 400 + GG +Q+AG S +L +++ LG F+ LPKAVLA I I +++ + Q+ ++ Sbjct: 406 LVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRS 465 Query: 401 LWHISRVDFLL 411 LW +R D L+ Sbjct: 466 LWKANRADLLI 476 >gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo sapiens] Length = 759 Score = 279 bits (713), Expect = 6e-75 Identities = 147/371 (39%), Positives = 230/371 (61%), Gaps = 2/371 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+A+ALLA +PPVFGLY+SF+PV IY L GT RH+S GTFA++S+M GS E L P+ L Sbjct: 108 GLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL- 166 Query: 101 GNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALH 160 N S I + DA RV VA+ ++ G +G+ ++ G + T+LSEP+V+ T+ AA+ Sbjct: 167 -NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 225 Query: 161 VLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNV 220 V +SQL + GL L G SL T+ + LP+S + +A++ +LV VK LN Sbjct: 226 VFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLND 285 Query: 221 RFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRIL 280 + + +LP PIPGE++ ++ A+ + + + R++V +VG +P G P+ PN +++ Sbjct: 286 KLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLV 345 Query: 281 ADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATT 340 + IA+V FA++ SL I A ++ Y +DSNQE +A G SNLI +F CFP S +++ + Sbjct: 346 GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRS 405 Query: 341 NLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQ 400 + GG +Q+AG S +L +++ LG F+ LPKAVLA I I +++ + Q+ ++ Sbjct: 406 LVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRS 465 Query: 401 LWHISRVDFLL 411 LW +R D L+ Sbjct: 466 LWKANRADLLI 476 >gi|4505697 pendrin [Homo sapiens] Length = 780 Score = 276 bits (706), Expect = 4e-74 Identities = 152/410 (37%), Positives = 245/410 (59%), Gaps = 10/410 (2%) Query: 20 KSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGT 79 K W L S T ++ GMA+ALLA+VP +GLY++FFP+L Y + GT RH+S G Sbjct: 81 KEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVGP 140 Query: 80 FAILSLMTGSAVERLVPEP--LVGNLSG-------IEKEQLDAQRVGVAAAVAFGSGALM 130 F ++SLM GS V + P+ LV + +G I+ D RV +A+A+ G + Sbjct: 141 FPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVGIIQ 200 Query: 131 LGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASL 190 L LQ+G + +L++P+V T+ AA VL+SQL +L +S G S+ TL + Sbjct: 201 LIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVEI 260 Query: 191 LTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVD 250 + ++ A+ T L++ + + VKELN RFR ++P PIP EV++ ++A+ + + ++++ Sbjct: 261 FQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKIPVPIPIEVIVTIIATAISYGANLE 320 Query: 251 TRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTID 310 Y IV +P GF P LP ++ +LA S IA+V++A++ S+ ++A KY YTID Sbjct: 321 KNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKYDYTID 380 Query: 311 SNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGP 370 NQEF+A G SN+ S FSCF + L+ T + GGKTQ+AG+ S +V+ +L LG Sbjct: 381 GNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALGK 440 Query: 371 FFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQVPGLCILS 420 L K+VLA + I++++ +F Q+ ++P+LW +++D ++ V CI+S Sbjct: 441 LLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWV-FTCIVS 489 >gi|4557535 solute carrier family 26, member 3 [Homo sapiens] Length = 764 Score = 260 bits (664), Expect = 3e-69 Identities = 146/404 (36%), Positives = 232/404 (57%), Gaps = 10/404 (2%) Query: 20 KSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGT 79 K W L S T + G+AFALL +PPV+GLY SFFP +IY GT RH+S G Sbjct: 70 KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGP 129 Query: 80 FAILSLMTG----SAVERLVPEPLVGNL----SGIEKEQLDAQRVGVAAA--VAFGSGAL 129 F ILS+M G AV + VP+ L + LD +RV VAAA V SG + Sbjct: 130 FPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGII 189 Query: 130 MLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLAS 189 L +L++G + +LSE ++ T+ AA+HVL+SQL + L++P S+FK L S Sbjct: 190 QLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYS 249 Query: 190 LLTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSV 249 + + + +++ A+L + + L ++ VKE+N RF+D+LP PIP E ++ ++A+ + + Sbjct: 250 VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF 309 Query: 250 DTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTI 309 R++V +VG + GF P+ P++ + D IA+V+FAV+ S+AS+++ KY Y + Sbjct: 310 KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPL 369 Query: 310 DSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLG 369 D NQE +A G N++ +F F S L+ + + GGKTQ+AGL +VL V+L +G Sbjct: 370 DGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIG 429 Query: 370 PFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQV 413 L K+VLA + + +++ + Q E+ +LW + D L+ + Sbjct: 430 FLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWI 473 >gi|45827802 prestin isoform c [Homo sapiens] Length = 516 Score = 258 bits (659), Expect = 1e-68 Identities = 142/374 (37%), Positives = 221/374 (59%), Gaps = 3/374 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+LA+VPP+FGLY+SF+PV++Y LGT RH+S G FA++SLM G RLVP+ +V Sbjct: 98 GLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157 Query: 101 --GNLSGIE-KEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGA 157 G ++ E DA RV VA +V SG + + V + G ++ +L+EP+V+ T+ A Sbjct: 158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217 Query: 158 ALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKE 217 A+HV S L L G+ R G FS+ + ++L + + L + + LL+ KE Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277 Query: 218 LNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELP 277 N RF+++LP PIP E V++ + + ++ Y V +VG LP G P P+ + Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337 Query: 278 RILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATL 337 + D++ IA+V F+V+ S+A A+K+ Y +D NQE +A G N I SLF F S +L Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397 Query: 338 ATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQE 397 + + + GGKTQLAG + ++L V+L G F LP+AVL+ I I +++ +F Q + Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457 Query: 398 LPQLWHISRVDFLL 411 LP W S+++ + Sbjct: 458 LPFFWRTSKIELTI 471 >gi|45827800 prestin isoform b [Homo sapiens] Length = 685 Score = 258 bits (659), Expect = 1e-68 Identities = 142/374 (37%), Positives = 221/374 (59%), Gaps = 3/374 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+LA+VPP+FGLY+SF+PV++Y LGT RH+S G FA++SLM G RLVP+ +V Sbjct: 98 GLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157 Query: 101 --GNLSGIE-KEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGA 157 G ++ E DA RV VA +V SG + + V + G ++ +L+EP+V+ T+ A Sbjct: 158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217 Query: 158 ALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKE 217 A+HV S L L G+ R G FS+ + ++L + + L + + LL+ KE Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277 Query: 218 LNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELP 277 N RF+++LP PIP E V++ + + ++ Y V +VG LP G P P+ + Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337 Query: 278 RILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATL 337 + D++ IA+V F+V+ S+A A+K+ Y +D NQE +A G N I SLF F S +L Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397 Query: 338 ATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQE 397 + + + GGKTQLAG + ++L V+L G F LP+AVL+ I I +++ +F Q + Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457 Query: 398 LPQLWHISRVDFLL 411 LP W S+++ + Sbjct: 458 LPFFWRTSKIELTI 471 Score = 30.4 bits (67), Expect = 4.5 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 4/50 (8%) Query: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQ 513 V V+LDF+ V F D+ G + + + + D I + LA C+A +Q Sbjct: 639 VHTVILDFTQVNFIDSVGVKTLAGIVKEYG----DVGIYVYLAGCSAFIQ 684 >gi|39752683 prestin isoform a [Homo sapiens] Length = 744 Score = 258 bits (659), Expect = 1e-68 Identities = 142/374 (37%), Positives = 221/374 (59%), Gaps = 3/374 (0%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+LA+VPP+FGLY+SF+PV++Y LGT RH+S G FA++SLM G RLVP+ +V Sbjct: 98 GLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157 Query: 101 --GNLSGIE-KEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGA 157 G ++ E DA RV VA +V SG + + V + G ++ +L+EP+V+ T+ A Sbjct: 158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217 Query: 158 ALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKE 217 A+HV S L L G+ R G FS+ + ++L + + L + + LL+ KE Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277 Query: 218 LNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELP 277 N RF+++LP PIP E V++ + + ++ Y V +VG LP G P P+ + Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337 Query: 278 RILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATL 337 + D++ IA+V F+V+ S+A A+K+ Y +D NQE +A G N I SLF F S +L Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397 Query: 338 ATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQE 397 + + + GGKTQLAG + ++L V+L G F LP+AVL+ I I +++ +F Q + Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457 Query: 398 LPQLWHISRVDFLL 411 LP W S+++ + Sbjct: 458 LPFFWRTSKIELTI 471 Score = 36.6 bits (83), Expect = 0.063 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523 V V+LDF+ V F D+ G + + + + D I + LA C+A V LTR + Sbjct: 639 VHTVILDFTQVNFIDSVGVKTLAGIVKEYG----DVGIYVYLAGCSAQVVNDLTRNRFFE 694 Query: 524 R-VTPDQLFVSVQDAAAYALGSLLR 547 + LF S+ DA LGS LR Sbjct: 695 NPALWELLFHSIHDA---VLGSQLR 716 >gi|100913030 solute carrier family 26 member 2 [Homo sapiens] Length = 739 Score = 247 bits (631), Expect = 2e-65 Identities = 141/388 (36%), Positives = 217/388 (55%), Gaps = 18/388 (4%) Query: 42 MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEP--- 98 +A++LLA PV+GLYTSFF +IY LLGT RH+S G F +L LM G V+R + + Sbjct: 127 IAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYD 186 Query: 99 ---------LVGNLSGIEKEQLD------AQRVGVAAAVAFGSGALMLGMFVLQLGVLST 143 +V N S + D + V + V F +G + M Q+G +S Sbjct: 187 NAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSV 246 Query: 144 FLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELT 203 +LS+ ++ +GA+ +L SQ LLGL+LPR G SL T + + +++ +L Sbjct: 247 YLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLI 306 Query: 204 ISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPG 263 S L L +L+P KELN F+ +L PIP E+V+V+ A++ + Y I G +P Sbjct: 307 TSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPT 366 Query: 264 GFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNL 323 GF P +P +P + D++ I+++ FA++ SL+ + A K+ YT+ +NQE A G N+ Sbjct: 367 GFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNI 426 Query: 324 ISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACI 383 I S F CF SA LA T + G TQL+G+ + V+L VLL + P FY L K+VL I Sbjct: 427 IPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVI 486 Query: 384 NISSMRQVFCQMQELPQLWHISRVDFLL 411 I ++R + ++LP++W ISR+D ++ Sbjct: 487 TIVNLRGALRKFRDLPKMWSISRMDTVI 514 Score = 42.7 bits (99), Expect = 9e-04 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523 + +V+D S + F D AG + +VR + I++LLAQCN V+ +LT Sbjct: 646 LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEA----IGIQVLLAQCNPTVRDSLTNGEYCK 701 Query: 524 RVTPDQLFVSVQDAAAYA 541 + + LF SV +A A+A Sbjct: 702 KEEENLLFYSVYEAMAFA 719 >gi|47131207 solute carrier family 26, member 1 isoform a [Homo sapiens] Length = 701 Score = 239 bits (609), Expect = 6e-63 Identities = 140/387 (36%), Positives = 224/387 (57%), Gaps = 18/387 (4%) Query: 42 MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVER-------- 93 +A++LLA + P++ LYTSFF LIY L+GT RH+S G F++L LM G V+R Sbjct: 88 IAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFD 147 Query: 94 -----LVPEPLVGNLSGIEKEQLDAQR----VGVAAAVAFGSGALMLGMFVLQLGVLSTF 144 L P L+G LD R + VA A+ +G + M VL+LG +S + Sbjct: 148 PSQDGLQPGANSSTLNG-SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAY 206 Query: 145 LSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTI 204 LS+P++ GA++ +L SQL LLG+ +PR G + T SLL +++ ++ Sbjct: 207 LSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVT 266 Query: 205 SALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGG 264 S + LA+L+ KEL+ R+R RL P+P E++++++A+++ + R+ + G +P G Sbjct: 267 STVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTG 326 Query: 265 FPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLI 324 F P +P + R+ D++ +ALV+ A S SLA + A + Y++ +NQE LA G N++ Sbjct: 327 FMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVL 386 Query: 325 SSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACIN 384 + CF SA LA + + G +TQL+ + S TVVL VLL L P F+ L ++VLAC+ Sbjct: 387 PAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVI 446 Query: 385 ISSMRQVFCQMQELPQLWHISRVDFLL 411 + S+R ++ +LP+LW +S D L+ Sbjct: 447 VVSLRGALRKVWDLPRLWRMSPADALV 473 >gi|20336272 solute carrier family 26, member 1 isoform a [Homo sapiens] Length = 701 Score = 239 bits (609), Expect = 6e-63 Identities = 140/387 (36%), Positives = 224/387 (57%), Gaps = 18/387 (4%) Query: 42 MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVER-------- 93 +A++LLA + P++ LYTSFF LIY L+GT RH+S G F++L LM G V+R Sbjct: 88 IAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFD 147 Query: 94 -----LVPEPLVGNLSGIEKEQLDAQR----VGVAAAVAFGSGALMLGMFVLQLGVLSTF 144 L P L+G LD R + VA A+ +G + M VL+LG +S + Sbjct: 148 PSQDGLQPGANSSTLNG-SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAY 206 Query: 145 LSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTI 204 LS+P++ GA++ +L SQL LLG+ +PR G + T SLL +++ ++ Sbjct: 207 LSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVT 266 Query: 205 SALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGG 264 S + LA+L+ KEL+ R+R RL P+P E++++++A+++ + R+ + G +P G Sbjct: 267 STVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTG 326 Query: 265 FPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLI 324 F P +P + R+ D++ +ALV+ A S SLA + A + Y++ +NQE LA G N++ Sbjct: 327 FMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVL 386 Query: 325 SSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACIN 384 + CF SA LA + + G +TQL+ + S TVVL VLL L P F+ L ++VLAC+ Sbjct: 387 PAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVI 446 Query: 385 ISSMRQVFCQMQELPQLWHISRVDFLL 411 + S+R ++ +LP+LW +S D L+ Sbjct: 447 VVSLRGALRKVWDLPRLWRMSPADALV 473 >gi|16418413 solute carrier family 26, member 9 isoform a [Homo sapiens] Length = 791 Score = 228 bits (580), Expect = 1e-59 Identities = 129/385 (33%), Positives = 220/385 (57%), Gaps = 7/385 (1%) Query: 36 STSIP-GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERL 94 S +P GMAFALLA++P V GLY+SFFP+L Y LG + GTFA++S++ G+ +L Sbjct: 83 SIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQL 142 Query: 95 VPEPL------VGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEP 148 PE N S ++ ++A+R+ V+A +A + + +G+ +Q G ++ +LSE Sbjct: 143 APESKFQVFNNATNESYVDTAAMEAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSES 202 Query: 149 VVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALS 208 ++ + A L +L+S L + GL++P G S+ T + LP ++ A L + +S Sbjct: 203 FIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALIS 262 Query: 209 LALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQP 268 A LV VKELN R+ ++ PIP E+++V++A+ + + +Y +QIVG + GFP P Sbjct: 263 GAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTP 322 Query: 269 LLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLF 328 + P +++ ++ + +A+VS+ ++ ++ A+K+ Y +DSNQE +A G SN S F Sbjct: 323 VSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFF 382 Query: 329 SCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSM 388 L+ T + AGGK+Q+A L VV+ +L LG + Y LPK+VL + ++ Sbjct: 383 KIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNL 442 Query: 389 RQVFCQMQELPQLWHISRVDFLLQV 413 + Q+ + LW S++D + V Sbjct: 443 KNSLKQLTDPYYLWRKSKLDCCIWV 467 Score = 30.0 bits (66), Expect = 5.9 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD--R 524 ++LD SGV+F D G ++ +L+S +++ L +A V ++ G+ + Sbjct: 665 LILDMSGVSFVDLMG----IKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS 720 Query: 525 VTPDQLFVSVQDAAAYA 541 + +F S+ DA +A Sbjct: 721 LECKHVFPSIHDAVLFA 737 >gi|217272867 solute carrier family 26, member 9 isoform b [Homo sapiens] Length = 887 Score = 228 bits (580), Expect = 1e-59 Identities = 129/385 (33%), Positives = 220/385 (57%), Gaps = 7/385 (1%) Query: 36 STSIP-GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERL 94 S +P GMAFALLA++P V GLY+SFFP+L Y LG + GTFA++S++ G+ +L Sbjct: 83 SIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQL 142 Query: 95 VPEPL------VGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEP 148 PE N S ++ ++A+R+ V+A +A + + +G+ +Q G ++ +LSE Sbjct: 143 APESKFQVFNNATNESYVDTAAMEAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSES 202 Query: 149 VVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALS 208 ++ + A L +L+S L + GL++P G S+ T + LP ++ A L + +S Sbjct: 203 FIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALIS 262 Query: 209 LALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQP 268 A LV VKELN R+ ++ PIP E+++V++A+ + + +Y +QIVG + GFP P Sbjct: 263 GAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTP 322 Query: 269 LLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLF 328 + P +++ ++ + +A+VS+ ++ ++ A+K+ Y +DSNQE +A G SN S F Sbjct: 323 VSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFF 382 Query: 329 SCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSM 388 L+ T + AGGK+Q+A L VV+ +L LG + Y LPK+VL + ++ Sbjct: 383 KIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNL 442 Query: 389 RQVFCQMQELPQLWHISRVDFLLQV 413 + Q+ + LW S++D + V Sbjct: 443 KNSLKQLTDPYYLWRKSKLDCCIWV 467 Score = 30.0 bits (66), Expect = 5.9 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD--R 524 ++LD SGV+F D G ++ +L+S +++ L +A V ++ G+ + Sbjct: 665 LILDMSGVSFVDLMG----IKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS 720 Query: 525 VTPDQLFVSVQDAAAYA 541 + +F S+ DA +A Sbjct: 721 LECKHVFPSIHDAVLFA 737 >gi|45827804 prestin isoform d [Homo sapiens] Length = 335 Score = 166 bits (419), Expect = 7e-41 Identities = 90/228 (39%), Positives = 137/228 (60%), Gaps = 3/228 (1%) Query: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100 G+AFA+LA+VPP+FGLY+SF+PV++Y LGT RH+S G FA++SLM G RLVP+ +V Sbjct: 98 GLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157 Query: 101 --GNLSGIE-KEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGA 157 G ++ E DA RV VA +V SG + + V + G ++ +L+EP+V+ T+ A Sbjct: 158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217 Query: 158 ALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKE 217 A+HV S L L G+ R G FS+ + ++L + + L + + LL+ KE Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277 Query: 218 LNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGF 265 N RF+++LP PIP E V++ + + ++ Y V +VG LP GF Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGF 325 >gi|16418457 solute carrier family 26, member 8 isoform a [Homo sapiens] Length = 970 Score = 157 bits (396), Expect = 3e-38 Identities = 110/389 (28%), Positives = 192/389 (49%), Gaps = 27/389 (6%) Query: 41 GMAFALLAS--VPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILS-------------- 84 G+ +LLA +PP+ Y +F +IY + G+ +S G+F ++S Sbjct: 110 GLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNN 169 Query: 85 --LMTGSAVERLVPEPLVGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLS 142 L+ GS V+ P L G K + V A F +G + L M VL LG ++ Sbjct: 170 GQLVMGSFVKNEFSAP--SYLMGYNKS------LSVVATTTFLTGIIQLIMGVLGLGFIA 221 Query: 143 TFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAEL 202 T+L E + A + ALH++LSQL + G+ + G S F + + ALP+++ + Sbjct: 222 TYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSI 281 Query: 203 TISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLP 262 + + L K + + F ++ P P E+ L++ +V+ S+ T ++ ++P Sbjct: 282 LVFLTVVVALRINKCIRISF-NQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIP 340 Query: 263 GGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASN 322 F P+ P+ + LP+I+ + ++LVS + L A ++Y+++SNQ+ +A G N Sbjct: 341 YSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCN 400 Query: 323 LISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLAC 382 ++SS F + +A T + +GG+ Q A L V+L +++ +G FFY LP AVLA Sbjct: 401 VVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAG 460 Query: 383 INISSMRQVFCQMQELPQLWHISRVDFLL 411 I +S++ + LP LW + D L Sbjct: 461 IILSNVIPYLETISNLPSLWRQDQYDCAL 489 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 5/91 (5%) Query: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523 V ++LDFS V + D+ G + V ++ + ++A I +L+A C++ + R D Sbjct: 721 VHTIILDFSMVHYVDSRG----LVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFD 776 Query: 524 R-VTPDQLFVSVQDAAAYALGSLLRGSSTRS 553 +T QLF+SV DA +AL + GSS S Sbjct: 777 AGITKTQLFLSVHDAVLFALSRKVIGSSELS 807 >gi|85540447 solute carrier family 26, member 11 [Homo sapiens] Length = 606 Score = 132 bits (333), Expect = 6e-31 Identities = 109/403 (27%), Positives = 183/403 (45%), Gaps = 56/403 (13%) Query: 37 TSIP-GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLV 95 T+IP +A+A +A +PP +GLY++F +Y LGT R ++ G AI+SL+ Sbjct: 61 TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYT---F 117 Query: 96 PEPLVGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTS 155 EP A +AF SG + L M VL+LG L F+S PV+K TS Sbjct: 118 HEP------------------AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTS 159 Query: 156 GAALHVLLSQLPSLLGL-SLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVP 214 AA+ + Q+ +LLGL ++PR F + + + + + + + LL+ Sbjct: 160 AAAVTIGFGQIKNLLGLQNIPR-----PFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLV 214 Query: 215 VKELNVRFRDRLPTPIPG---------------EVVLVLLASVLCFTSSVDTRYQVQIVG 259 +K + P PG ++V A+++ ++ V + G Sbjct: 215 LKLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTG 274 Query: 260 LLPGGFPQPLLP-----------NLAELPRILADSLPIA-LVSFAVSASLASIHADKYSY 307 G P +P + E+ + + L + L+ S ++A A + +Y Sbjct: 275 ETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNY 334 Query: 308 TIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLW 367 ID+NQE LA G +N++ SL S +P + + T + +G T GL + +VL L + Sbjct: 335 RIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDY 394 Query: 368 LGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFL 410 L FYY+PK+ LA + I ++ +F + LW + R+D L Sbjct: 395 LTSLFYYIPKSALAAVIIMAVAPLF-DTKIFRTLWRVKRLDLL 436 >gi|20336285 solute carrier family 26, member 8 isoform b [Homo sapiens] Length = 865 Score = 91.3 bits (225), Expect = 2e-18 Identities = 52/178 (29%), Positives = 96/178 (53%) Query: 234 VVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAV 293 ++ ++ +V+ S+ T ++ ++P F P+ P+ + LP+I+ + ++LVS + Sbjct: 207 IIQIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFL 266 Query: 294 SASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLA 353 L A ++Y+++SNQ+ +A G N++SS F + +A T + +GG+ Q A Sbjct: 267 LIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFA 326 Query: 354 GLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLL 411 L V+L +++ +G FFY LP AVLA I +S++ + LP LW + D L Sbjct: 327 SLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCAL 384 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 5/91 (5%) Query: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523 V ++LDFS V + D+ G + V ++ + ++A I +L+A C++ + R D Sbjct: 616 VHTIILDFSMVHYVDSRG----LVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFD 671 Query: 524 R-VTPDQLFVSVQDAAAYALGSLLRGSSTRS 553 +T QLF+SV DA +AL + GSS S Sbjct: 672 AGITKTQLFLSVHDAVLFALSRKVIGSSELS 702 Score = 30.0 bits (66), Expect = 5.9 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 41 GMAFALLAS--VPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLM 86 G+ +LLA +PP+ Y +F +IY + G+ +S G+F ++S + Sbjct: 110 GLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSAL 157 >gi|217272870 solute carrier family 26, member 9 isoform c [Homo sapiens] Length = 459 Score = 80.1 bits (196), Expect = 5e-15 Identities = 43/135 (31%), Positives = 74/135 (54%) Query: 279 ILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLA 338 ++ + +A+VS+ ++ ++ A+K+ Y +DSNQE +A G SN S F L+ Sbjct: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60 Query: 339 TTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQEL 398 T + AGGK+Q+A L VV+ +L LG + Y LPK+VL + +++ Q+ + Sbjct: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120 Query: 399 PQLWHISRVDFLLQV 413 LW S++D + V Sbjct: 121 YYLWRKSKLDCCIWV 135 Score = 30.0 bits (66), Expect = 5.9 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Query: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD--R 524 ++LD SGV+F D G ++ +L+S +++ L +A V ++ G+ + Sbjct: 333 LILDMSGVSFVDLMG----IKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS 388 Query: 525 VTPDQLFVSVQDAAAYA 541 + +F S+ DA +A Sbjct: 389 LECKHVFPSIHDAVLFA 405 >gi|20336274 solute carrier family 26, member 1 isoform b [Homo sapiens] Length = 224 Score = 67.0 bits (162), Expect = 4e-11 Identities = 36/89 (40%), Positives = 55/89 (61%), Gaps = 7/89 (7%) Query: 42 MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLVG 101 +A++LLA + P++ LYTSFF LIY L+GT RH+S G F++L LM G V+R + Sbjct: 88 IAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDREL------ 141 Query: 102 NLSGIEKEQLDAQRVGVAAAVAFGSGALM 130 L+G + Q D + G ++ GS A++ Sbjct: 142 QLAGFDPSQ-DGLQPGANSSTLNGSAAML 169 >gi|93141208 SLAIN motif family, member 1 A [Homo sapiens] Length = 349 Score = 30.4 bits (67), Expect = 4.5 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 15/68 (22%) Query: 270 LPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFS 329 +PNLA +P + A+S++++S + S + DS+ HGA N IS + S Sbjct: 185 MPNLARMPS-----------TTAISSNISSPVTVRNSQSFDSS----LHGAGNGISRIQS 229 Query: 330 CFPNSATL 337 C P+ L Sbjct: 230 CIPSPGQL 237 >gi|21389389 SLAIN motif family, member 1 B [Homo sapiens] Length = 305 Score = 30.4 bits (67), Expect = 4.5 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 15/68 (22%) Query: 270 LPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFS 329 +PNLA +P + A+S++++S + S + DS+ HGA N IS + S Sbjct: 141 MPNLARMPS-----------TTAISSNISSPVTVRNSQSFDSS----LHGAGNGISRIQS 185 Query: 330 CFPNSATL 337 C P+ L Sbjct: 186 CIPSPGQL 193 >gi|164607124 Fanconi anemia, complementation group I isoform 1 [Homo sapiens] Length = 1328 Score = 30.0 bits (66), Expect = 5.9 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 16/102 (15%) Query: 77 TGTFAILSLMTG---------SAVERLVPEP--LVGNLSG-IEKEQLDAQRVGVAAAVAF 124 T FAI++L T S E+++ E L+ L G + +E L + A++ A Sbjct: 1069 TNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEE----ASSQAT 1124 Query: 125 GSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQL 166 + ++QLG L TF E V AL SG+ + LL L Sbjct: 1125 LPNQPVEKAIIMQLGTLLTFFHELVQTALPSGSCVDTLLKDL 1166 >gi|82830440 Fanconi anemia, complementation group I isoform 2 [Homo sapiens] Length = 1268 Score = 30.0 bits (66), Expect = 5.9 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 16/102 (15%) Query: 77 TGTFAILSLMTG---------SAVERLVPEP--LVGNLSG-IEKEQLDAQRVGVAAAVAF 124 T FAI++L T S E+++ E L+ L G + +E L + A++ A Sbjct: 1009 TNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEE----ASSQAT 1064 Query: 125 GSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQL 166 + ++QLG L TF E V AL SG+ + LL L Sbjct: 1065 LPNQPVEKAIIMQLGTLLTFFHELVQTALPSGSCVDTLLKDL 1106 >gi|31881740 solute carrier family 12 (potassium/chloride transporters), member 9 [Homo sapiens] Length = 914 Score = 30.0 bits (66), Expect = 5.9 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 5/145 (3%) Query: 48 ASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAV--ERLVPEPLVGNLSG 105 +S+PP FG +T F + LG G T A+++ + AV N+SG Sbjct: 230 SSLPPRFGHFTGFNSSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSG 289 Query: 106 IEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEP--VVKALTSGAALHVLL 163 K+ A +G AVA+ +L F+ T L E +A++ L VL+ Sbjct: 290 ELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPL-VLI 348 Query: 164 SQLPSLLGLSLPRQIGCFSLFKTLA 188 + L S+ IG + LA Sbjct: 349 GIYATALSASMSSLIGASRILHALA 373 >gi|33469987 asteroid homolog 1 [Homo sapiens] Length = 679 Score = 30.0 bits (66), Expect = 5.9 Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 129 LMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLA 188 L +GM++ QL LST L EP + L SG+ +H L QL L S+ + K L Sbjct: 549 LQMGMYLNQL--LSTPLPEPDLTRLYSGSLVHGLCQQL--LASTSVESLLSICPEAKQLY 604 Query: 189 SLLTALPRS-SPAEL 202 L RS +PAE+ Sbjct: 605 EYLFNATRSYAPAEI 619 >gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] Length = 4753 Score = 29.6 bits (65), Expect = 7.7 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 11/85 (12%) Query: 183 LFKTLASLLTA-LPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLAS 241 L L +L +A L SSPA L LL P +EL V D LP L Sbjct: 61 LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLP----------FLEQ 110 Query: 242 VLCFTSSVDTRYQVQIVGLLPGGFP 266 + C+ V T + ++G + FP Sbjct: 111 LYCWAPWVQTHLHLDLLGAIVQAFP 135 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.137 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,438,945 Number of Sequences: 37866 Number of extensions: 938289 Number of successful extensions: 2137 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 2060 Number of HSP's gapped (non-prelim): 57 length of query: 563 length of database: 18,247,518 effective HSP length: 107 effective length of query: 456 effective length of database: 14,195,856 effective search space: 6473310336 effective search space used: 6473310336 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.