Guide to the Human Genome
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Search of human proteins with 62751964

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62751964 YOD1 OTU deubiquinating enzyme 1 homolog [Homo
sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62751964 YOD1 OTU deubiquinating enzyme 1 homolog [Homo sapiens]   714   0.0  
gi|36029914 valosin containing protein (p97)/p47 complex interac...    46   6e-05
gi|115430233 ubiquitin-like with PHD and ring finger domains 1 i...    35   0.076
gi|46409282 OTU domain containing 6A [Homo sapiens]                    35   0.076
gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sap...    34   0.17 
gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens]    34   0.17 
gi|40807496 OTU domain containing 4 protein isoform 1 [Homo sapi...    34   0.17 
gi|157364937 OTU domain containing 6B [Homo sapiens]                   33   0.38 
gi|115430235 ubiquitin-like with PHD and ring finger domains 1 i...    31   1.4  
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                30   2.5  
gi|40807366 PP3111 protein [Homo sapiens]                              30   2.5  
gi|239740757 PREDICTED: hypothetical protein [Homo sapiens]            30   4.2  
gi|239740703 PREDICTED: hypothetical protein [Homo sapiens]            30   4.2  
gi|151101266 TERF1 (TRF1)-interacting nuclear factor 2 isoform 1...    30   4.2  
gi|151101235 TERF1 (TRF1)-interacting nuclear factor 2 isoform 2...    30   4.2  
gi|134133292 WD repeat domain 27 [Homo sapiens]                        29   5.5  

>gi|62751964 YOD1 OTU deubiquinating enzyme 1 homolog [Homo sapiens]
          Length = 348

 Score =  714 bits (1843), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVL 60
           MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVL
Sbjct: 1   MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVL 60

Query: 61  QGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLII 120
           QGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLII
Sbjct: 61  QGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLII 120

Query: 121 EEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAP 180
           EEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAP
Sbjct: 121 EEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAP 180

Query: 181 EMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVD 240
           EMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVD
Sbjct: 181 EMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVD 240

Query: 241 TQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALEL 300
           TQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALEL
Sbjct: 241 TQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALEL 300

Query: 301 ADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV 348
           ADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV
Sbjct: 301 ADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV 348


>gi|36029914 valosin containing protein (p97)/p47 complex
           interacting protein 1 [Homo sapiens]
          Length = 1222

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 6/143 (4%)

Query: 6   KGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVLQGLSS 65
           KG+   V P+    G  S  A  TKA      P    T    ++R    DG   +  L S
Sbjct: 740 KGQPRTVSPSTIRDGPSSAPATPTKA------PYSPTTSKEKKIRITTNDGRQSMVTLKS 793

Query: 66  RTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLIIEEDQT 125
            T   ELQ  IA    I P  Q I  G+PP+ L         E +P+Q GD + IE  ++
Sbjct: 794 STTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKS 853

Query: 126 RPRSSPAFTKRGASSYVRETLPV 148
           +     +     A +  +E + V
Sbjct: 854 KAEGGQSAAAHSAHTVKQEDIAV 876


>gi|115430233 ubiquitin-like with PHD and ring finger domains 1
           isoform 2 [Homo sapiens]
          Length = 806

 Score = 35.4 bits (80), Expect = 0.076
 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 44  DTMWRLRCKAKDG--THVLQGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLS 101
           DTMW ++ +  DG  TH +  LS  T+V EL+ +I  +  + PG QR+          + 
Sbjct: 12  DTMW-IQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY----RGKQME 66

Query: 102 NGDTILE-DLPIQSGDMLIIEEDQTRPRSS 130
           +G T+ + ++ +     L++ +    P S+
Sbjct: 67  DGHTLFDYEVRLNDTIQLLVRQSLVLPHST 96


>gi|46409282 OTU domain containing 6A [Homo sapiens]
          Length = 288

 Score = 35.4 bits (80), Expect = 0.076
 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 15/124 (12%)

Query: 149 LTRTVVPADNSCLFTSVY----YVVEGGVLNPACAPEMRRLIAQIVA--SDPDFYSEAIL 202
           L    +PAD  C++ ++     + V   +L    A  M++ + + +   S+P+  S++  
Sbjct: 141 LEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSNPET-SDSFG 199

Query: 203 GKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVV--DTQTVRIDRFGEDAGYTKR-V 259
                 YCD I R   WGG +E+  LS   +  I V+  D+ T+ I   GE+  Y K+ +
Sbjct: 200 YDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLII---GEE--YVKKPI 254

Query: 260 LLIY 263
           +L+Y
Sbjct: 255 ILVY 258


>gi|156630992 OTU domain containing 4 protein isoform 3 [Homo
           sapiens]
          Length = 1049

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 199 EAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKR 258
           EA +  + +EY   ++    W G +EIS LS  Y+ +  +     V   +  E+    K 
Sbjct: 15  EAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKV 74

Query: 259 VLLIYDGIHYD 269
           +L   +G HYD
Sbjct: 75  LLCFSNGNHYD 85


>gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens]
          Length = 145

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 199 EAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKR 258
           EA +  + +EY   ++    W G +EIS LS  Y+ +  +     V   +  E+    K 
Sbjct: 15  EAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKV 74

Query: 259 VLLIYDGIHYD 269
           +L   +G HYD
Sbjct: 75  LLCFSNGNHYD 85


>gi|40807496 OTU domain containing 4 protein isoform 1 [Homo
           sapiens]
          Length = 1048

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 199 EAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKR 258
           EA +  + +EY   ++    W G +EIS LS  Y+ +  +     V   +  E+    K 
Sbjct: 15  EAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKV 74

Query: 259 VLLIYDGIHYD 269
           +L   +G HYD
Sbjct: 75  LLCFSNGNHYD 85


>gi|157364937 OTU domain containing 6B [Homo sapiens]
          Length = 323

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 26/139 (18%)

Query: 154 VPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTN------- 206
           +P+D  C+    Y  +E  +    CA  +  L +Q          + +   TN       
Sbjct: 182 IPSDGHCM----YKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMY 237

Query: 207 -----QEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKR-VL 260
                Q+YC+ I     WGG +E+  LS   Q  I ++   +  I   GE+  Y+K+ ++
Sbjct: 238 TPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPI-IVGEE--YSKKPLI 294

Query: 261 LIYD------GIHYDPLQR 273
           L+Y       G HY+ + R
Sbjct: 295 LVYMRHAYGLGEHYNSVTR 313


>gi|115430235 ubiquitin-like with PHD and ring finger domains 1
           isoform 1 [Homo sapiens]
          Length = 793

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 8/88 (9%)

Query: 46  MWRLRCKAKDG--THVLQGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNG 103
           MW ++ +  DG  TH +  LS  T+V EL+ +I  +  + PG QR+          + +G
Sbjct: 1   MW-IQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFY----RGKQMEDG 55

Query: 104 DTILE-DLPIQSGDMLIIEEDQTRPRSS 130
            T+ + ++ +     L++ +    P S+
Sbjct: 56  HTLFDYEVRLNDTIQLLVRQSLVLPHST 83


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 18/37 (48%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 14  PAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLR 50
           PAPG PGG   Q AG+ AGP  A P    T    R R
Sbjct: 129 PAPGAPGG--PQLAGSSAGPVTAAPSQPPTTCSSRFR 163


>gi|40807366 PP3111 protein [Homo sapiens]
          Length = 473

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 2/34 (5%)

Query: 180 PEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWI 213
           PE R LI Q  A+DP+ + +A L    Q+YCD I
Sbjct: 71  PEDRPLIVQFCANDPEVFVQAAL--LAQDYCDAI 102


>gi|239740757 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 83  APGGQRILVGYP-PECLDLSNGDTILEDLPIQSGD 116
           A GG R+ VGY   ECL+   G ++ ED  +  GD
Sbjct: 181 ARGGVRVWVGYTGAECLEWEVGRSLFEDSRVNEGD 215


>gi|239740703 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 83  APGGQRILVGYP-PECLDLSNGDTILEDLPIQSGD 116
           A GG R+ VGY   ECL+   G ++ ED  +  GD
Sbjct: 181 ARGGVRVWVGYTGAECLEWEVGRSLFEDSRVNEGD 215


>gi|151101266 TERF1 (TRF1)-interacting nuclear factor 2 isoform 1
           [Homo sapiens]
          Length = 451

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 3/37 (8%)

Query: 52  KAKDGTHVLQGLSSRTRVRELQGQIAAITGIAPGGQR 88
           KAK GTH+ QG SSRT    L G+      +AP G+R
Sbjct: 233 KAKPGTHLPQGPSSRTHPEPLAGR---HFNLAPLGRR 266


>gi|151101235 TERF1 (TRF1)-interacting nuclear factor 2 isoform 2
           [Homo sapiens]
          Length = 354

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 3/37 (8%)

Query: 52  KAKDGTHVLQGLSSRTRVRELQGQIAAITGIAPGGQR 88
           KAK GTH+ QG SSRT    L G+      +AP G+R
Sbjct: 233 KAKPGTHLPQGPSSRTHPEPLAGR---HFNLAPLGRR 266


>gi|134133292 WD repeat domain 27 [Homo sapiens]
          Length = 857

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 18/76 (23%)

Query: 8   RHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVLQGLSSRT 67
           RHF  HP  G+P G++    G  A                   C A+D    +  + S T
Sbjct: 777 RHFEGHPTRGYPCGIAFSPCGRFAA------------------CGAEDRHAYVYEMGSST 818

Query: 68  RVRELQGQIAAITGIA 83
               L G    +TG+A
Sbjct: 819 FSHRLAGHTDTVTGVA 834


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,904,051
Number of Sequences: 37866
Number of extensions: 714419
Number of successful extensions: 2152
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2139
Number of HSP's gapped (non-prelim): 17
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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