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Search of human proteins with 62000702
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
(1271 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 2596 0.0
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 771 0.0
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 770 0.0
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 770 0.0
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 766 0.0
gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 191 3e-48
gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 191 3e-48
gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 191 3e-48
gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 191 3e-48
gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens] 183 1e-45
gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens] 183 1e-45
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens] 176 1e-43
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens] 176 2e-43
gi|4758156 diacylglycerol kinase, iota [Homo sapiens] 136 1e-31
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens] 135 3e-31
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens] 134 6e-31
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens] 134 6e-31
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens] 134 7e-31
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens] 134 7e-31
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens] 132 2e-30
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 130 6e-30
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 105 3e-22
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 105 3e-22
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 105 3e-22
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 105 3e-22
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 97 1e-19
gi|116284392 mucin 2 precursor [Homo sapiens] 95 5e-19
gi|47132519 Ras association and pleckstrin homology domains 1 is... 92 4e-18
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 88 5e-17
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 88 5e-17
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 2596 bits (6728), Expect = 0.0
Identities = 1271/1271 (100%), Positives = 1271/1271 (100%)
Query: 1 MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPE 60
MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPE
Sbjct: 1 MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPE 60
Query: 61 LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE 120
LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE
Sbjct: 61 LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE 120
Query: 121 SAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC 180
SAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC
Sbjct: 121 SAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC 180
Query: 181 LLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLV 240
LLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLV
Sbjct: 181 LLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLV 240
Query: 241 QGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEW 300
QGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEW
Sbjct: 241 QGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEW 300
Query: 301 INIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEV 360
INIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEV
Sbjct: 301 INIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEV 360
Query: 361 CKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCG 420
CKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCG
Sbjct: 361 CKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCG 420
Query: 421 SYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFW 480
SYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFW
Sbjct: 421 SYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFW 480
Query: 481 NLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFA 540
NLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFA
Sbjct: 481 NLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFA 540
Query: 541 RFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLD 600
RFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLD
Sbjct: 541 RFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLD 600
Query: 601 ILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKIL 660
ILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKIL
Sbjct: 601 ILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKIL 660
Query: 661 KAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDV 720
KAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDV
Sbjct: 661 KAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDV 720
Query: 721 LAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQV 780
LAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQV
Sbjct: 721 LAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQV 780
Query: 781 EQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNL 840
EQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNL
Sbjct: 781 EQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNL 840
Query: 841 DHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGT 900
DHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGT
Sbjct: 841 DHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGT 900
Query: 901 KELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPA 960
KELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPA
Sbjct: 901 KELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPA 960
Query: 961 IDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPG 1020
IDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPG
Sbjct: 961 IDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPG 1020
Query: 1021 LIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQH 1080
LIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQH
Sbjct: 1021 LIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQH 1080
Query: 1081 LARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETL 1140
LARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETL
Sbjct: 1081 LARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETL 1140
Query: 1141 SRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPI 1200
SRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPI
Sbjct: 1141 SRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPI 1200
Query: 1201 FVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEG 1260
FVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEG
Sbjct: 1201 FVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEG 1260
Query: 1261 DDPLTPSRSQL 1271
DDPLTPSRSQL
Sbjct: 1261 DDPLTPSRSQL 1271
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 771 bits (1990), Expect = 0.0
Identities = 456/1120 (40%), Positives = 644/1120 (57%), Gaps = 118/1120 (10%)
Query: 213 RIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCR 272
R K +KEG +LK +SF+RWK RYF ++G+ LY+A F+ +DLS A+VAE+S +
Sbjct: 62 RTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEASTK 121
Query: 273 NLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYS 332
N +SF +ITP R++ L A NRK+ME+WI+ +K++Q E Y++ A N GMH WY+
Sbjct: 122 NANNSFTIITPFRRLMLCAENRKEMEDWISSLKSVQTREPYEV-AQFNVEHFSGMHNWYA 180
Query: 333 SYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTL-SITDDLLLP 391
R CNVCRES+ ++ + CEVCK K+H+ CA+RA+ +CKW TL SI D++
Sbjct: 181 CSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIED 240
Query: 392 ADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCF 451
D V MPHQW+EGN+PVS++CAVC ++CGS RLQD++CLWC + VH C+ + C
Sbjct: 241 EDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPL 300
Query: 452 RSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRK 511
+ S+IPP AL+ DG + F C PLL+F+NSKSGD+QG+ FLR+
Sbjct: 301 GQCKVSIIPPIALNSTDSDGFCRATFSF--------CVSPLLVFVNSKSGDNQGVKFLRR 352
Query: 512 FKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQL 571
FKQ LNP+QVFDL+ GGP GL +F+ F FRILVCGGDGSV WVLS ID L+++CQL
Sbjct: 353 FKQLLNPAQVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQL 412
Query: 572 AVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRE--TPRQTPL 629
V+PLGTGNDLARVLGWG ++ IL ++E+AS ++LDRWS+M E P + L
Sbjct: 413 GVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPPKASL 472
Query: 630 LKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKA 689
L G E E + +S AT L KIL + +I + + LC V+DFV + K
Sbjct: 473 LPGPPEASE---EFYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKT 529
Query: 690 WGQIKQNNTAIVSVILKSDLMYDRLSVLID------------------VLAEEAAATSAE 731
+ + +N +V K ++ ++L L+ ++ E+A +S+E
Sbjct: 530 YDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESSSE 589
Query: 732 KSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQT 791
+S E + D P K + E+ +A SL+K+++ +I + + +D+ +
Sbjct: 590 ESLGESKEQLGDDVTK--PSSQKAVKPR-EIMLRANSLKKAVRQVIEEAGKVMDDPTVHP 646
Query: 792 ISVKNFSSTFFLEDDPEDINQ-------------TSPRRRSRRGTLSS------------ 826
N SS + + E + T+PR R +
Sbjct: 647 CEPANQSSDYDSTETDESKEEAKDDGAKESITVKTAPRSPDARASYGHSQTDSVPGPAVA 706
Query: 827 ----------------------ISSLKSEDLDN----LNLDHLHFTP------ESI-RFK 853
+S+ + N N+D TP +S+ +
Sbjct: 707 ASKENLPVLNTRIICPGLRAGLAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYS 766
Query: 854 EKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEE 913
EKCVMNNYFGIGLDAKISL+FN +R+EHP + SR KN MWYG+LGT+ELLQRSY+ LE+
Sbjct: 767 EKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQ 826
Query: 914 RVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFG 973
RV LECDG+ I LP+LQGI VLNI SYAGG NFWG + AP+ DD LEVVAIF
Sbjct: 827 RVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAIFD 886
Query: 974 SVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQML 1033
S+QMA+SR+I L HHRIAQC V ITI G+EG+PVQVDGEAW+Q PG+IKI +KN AQML
Sbjct: 887 SMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQML 946
Query: 1034 TRDRDFENSMKMWEYKHTEIQAAPQPQLD-FQDSQESLSDEEYAQMQHLARLAENLISKL 1092
TRDR FE+++K WE K P + + L+ EE +QMQ ++ AE LI+++
Sbjct: 947 TRDRAFESTLKSWEDKQKCDSGKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRI 1006
Query: 1093 NDLSKIHQHV-SVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFS 1151
D + IH + L +VNA ++ LN A+ E+L+R+ A ++ +
Sbjct: 1007 CDAATIHCLLEQELAHAVNACSHALN-------------KANPRCPESLTRDTATEIAIN 1053
Query: 1152 LKGLYDDTTAFLDEKLLRSAED--ETALQSALDAMNKEFKKLSEIDWMNPIFVP---EEK 1206
+K LY++T + L ++ E E + +AL ++ E +KL+EI W+ I P EE
Sbjct: 1054 VKALYNETESLLVGRVPLQLESPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDEEP 1113
Query: 1207 SSDTDSRSLRLKI--KFPKLGKKKVEEERKPKSGQSVQSF 1244
D R+ R + PK K+KV++++ S Q VQ +
Sbjct: 1114 PMDCTKRNNRSTVFRIVPKFKKEKVQKQK--TSSQPVQKW 1151
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 770 bits (1989), Expect = 0.0
Identities = 455/1119 (40%), Positives = 644/1119 (57%), Gaps = 119/1119 (10%)
Query: 213 RIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCR 272
R K +KEG +LK +SF+RWK RYF ++G+ LY+A F+ +DLS A+VAE+S +
Sbjct: 62 RTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKSLIFDEVDLSDASVAEASTK 121
Query: 273 NLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYS 332
N +SF +ITP R++ L A NRK+ME+WI+ +K++Q E Y++ A N GMH WY+
Sbjct: 122 NANNSFTIITPFRRLMLCAENRKEMEDWISSLKSVQTREPYEV-AQFNVEHFSGMHNWYA 180
Query: 333 SYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTL-SITDDLLLP 391
R CNVCRES+ ++ + CEVCK K+H+ CA+RA+ +CKW TL SI D++
Sbjct: 181 CSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIED 240
Query: 392 ADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCF 451
D V MPHQW+EGN+PVS++CAVC ++CGS RLQD++CLWC + VH C+ + C
Sbjct: 241 EDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPL 300
Query: 452 RSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRK 511
+ S+IPP AL+ DG + F C PLL+F+NSKSGD+QG+ FLR+
Sbjct: 301 GQCKVSIIPPIALNSTDSDGFCRATFSF--------CVSPLLVFVNSKSGDNQGVKFLRR 352
Query: 512 FKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQL 571
FKQ LNP+QVFDL+ GGP GL +F+ F FRILVCGGDGSV WVLS ID L+++CQL
Sbjct: 353 FKQLLNPAQVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQL 412
Query: 572 AVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRE--TPRQTPL 629
V+PLGTGNDLARVLGWG ++ IL ++E+AS ++LDRWS+M E P + L
Sbjct: 413 GVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPPKASL 472
Query: 630 LKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKA 689
L G E E + +S AT L KIL + +I + + LC V+DFV + K
Sbjct: 473 LPGPPEASE---EFYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKT 529
Query: 690 WGQIKQNNTAIVSVILKSDLMYDRLSVLID------------------VLAEEAAATSAE 731
+ + +N +V K ++ ++L L+ ++ E+A +S+E
Sbjct: 530 YDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESSSE 589
Query: 732 KSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQT 791
+S E + D P K + E+ +A SL+K+++ +I + + +D+ +
Sbjct: 590 ESLGESKEQLGDDVTK--PSSQKAVKPR-EIMLRANSLKKAVRQVIEEAGKVMDDPTVHP 646
Query: 792 ISVKNFSSTFFLEDDPEDINQ-------------TSPRRRSRRGTLSS------------ 826
N SS + + E + T+PR R +
Sbjct: 647 CEPANQSSDYDSTETDESKEEAKDDGAKESITVKTAPRSPDARASYGHSQTDSVPGPAVA 706
Query: 827 ----------------------ISSLKSEDLDN----LNLDHLHFTP------ESI-RFK 853
+S+ + N N+D TP +S+ +
Sbjct: 707 ASKENLPVLNTRIICPGLRAGLAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYS 766
Query: 854 EKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEE 913
EKCVMNNYFGIGLDAKISL+FN +R+EHP + SR KN MWYG+LGT+ELLQRSY+ LE+
Sbjct: 767 EKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQ 826
Query: 914 RVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFG 973
RV LECDG+ I LP+LQGI VLNI SYAGG NFWG + AP+ DD LEVVAIF
Sbjct: 827 RVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAIFD 886
Query: 974 SVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQML 1033
S+QMA+SR+I L HHRIAQC V ITI G+EG+PVQVDGEAW+Q PG+IKI +KN AQML
Sbjct: 887 SMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQML 946
Query: 1034 TRDRDFENSMKMWEYKHTEIQAAPQPQLD-FQDSQESLSDEEYAQMQHLARLAENLISKL 1092
TRDR FE+++K WE K P + + L+ EE +QMQ ++ AE LI+++
Sbjct: 947 TRDRAFESTLKSWEDKQKCDSGKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRI 1006
Query: 1093 NDLSKIHQHV-SVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFS 1151
D + IH + L +VNA ++ LN A+ E+L+R+ A ++ +
Sbjct: 1007 CDAATIHCLLEQELAHAVNACSHALN-------------KANPRCPESLTRDTATEIAIN 1053
Query: 1152 LKGLYDDTTAFLDEKLLRSAED--ETALQSALDAMNKEFKKLSEIDWMNPIFVP---EEK 1206
+K LY++T + L ++ E E + +AL ++ E +KL+EI W+ I P EE
Sbjct: 1054 VKALYNETESLLVGRVPLQLESPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDEEP 1113
Query: 1207 SSDTDSRSLRLKI--KFPKLGKKKVEEER---KPKSGQS 1240
D R+ R + PK K+KV++++ +P SG +
Sbjct: 1114 PMDCTKRNNRSTVFRIVPKFKKEKVQKQKTSSQPGSGDT 1152
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 770 bits (1989), Expect = 0.0
Identities = 473/1187 (39%), Positives = 662/1187 (55%), Gaps = 134/1187 (11%)
Query: 147 PELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPR 206
P P+P P P E + + PEA P SP + R + TS
Sbjct: 9 PPGPPQPPPPPPPEESSDSEPEAEPG---SPQKLI---------RKVSTSGQ-------- 48
Query: 207 TPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATV 266
R K I+KEG + K NSF+R K RYF ++G+ LY+A F+ +DL+ A+V
Sbjct: 49 -----IRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASV 103
Query: 267 AESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVG 326
AESS +N+ +SF VITP RK+ L A NRK+ME+WI +KT+Q E ++ P + G
Sbjct: 104 AESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFE-PTQYSMDHFSG 162
Query: 327 MHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTL-SIT 385
MH WY+ R +CNVCRE++ ++ + CEVCK K+H+ CA+RA+ +CKW TL SI
Sbjct: 163 MHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIG 222
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
D++ AD + MPHQW+EGN+PVS++C VC ++CGS RLQD+RCLWC + VH C+
Sbjct: 223 KDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESL 282
Query: 446 SKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQG 505
+C + SVIPPTAL+ DG FW +C+ PLL+F+NSKSGD+QG
Sbjct: 283 LTKCPLGLCKVSVIPPTALNSIDSDG-------FWKASCPPSCTSPLLVFVNSKSGDNQG 335
Query: 506 IVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGL 565
+ FLR+FKQ LNP+QVFDL+ GGP GL +F+ F FRILVCGGDGSV WVLS ID+ L
Sbjct: 336 VKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNL 395
Query: 566 HEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRET-- 623
H++CQL V+PLGTGNDLARVLGWG+ + IL ++E+AS ++LDRWSVM E
Sbjct: 396 HKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKL 455
Query: 624 PRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFV 683
PRQ + + + +S A L+KIL + + +I + + LC V+DFV
Sbjct: 456 PRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFV 515
Query: 684 VDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKS-----ATEYA 738
+ KA+ + +++ + K ++ ++L L+ L +E+ A+S+ + A E
Sbjct: 516 ARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAE 575
Query: 739 D--------SSKADR--KPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEES 788
D S DR P I + + +L +A SL+K+++ II E+A+DE++
Sbjct: 576 DGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQN 635
Query: 789 RQTISVKNFSSTFFLEDDPEDINQT------------SPRRRSRR-------------GT 823
QT + F L + E ++ P+ RS+R G+
Sbjct: 636 AQTQEQEGF--VLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGS 693
Query: 824 LSSISSL-------KSEDLDNLN----------------------------LDHLHFTPE 848
LS SS + L LN D + PE
Sbjct: 694 LSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPE 753
Query: 849 SIR-FKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRS 907
++ + EKCVMNNYFGIGLDAKISLDFN +RDEHP + SR KN MWYG+LGTKELL R+
Sbjct: 754 TLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRT 813
Query: 908 YRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLE 967
Y+ LE++V LECDG I LP+LQGI VLNI SYAGG NFWG + AP+ DD LE
Sbjct: 814 YKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILE 873
Query: 968 VVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYK 1027
VVA+FGS+QMA+SR+I L HHRIAQC V I+I G+EG+PVQVDGEAW+Q PG I+I +K
Sbjct: 874 VVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHK 933
Query: 1028 NAAQMLTRDRDFENSMKMWEYKH-TEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAE 1086
N AQ LTRDR FE+++K WE K E+ P L E LS+EE QM + A
Sbjct: 934 NRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSL----HPEMLSEEEATQMDQFGQAAG 989
Query: 1087 NLISKLNDLSKIHQHV-SVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDA 1145
LI + ++++ H+ + L +VNAS+ + D YG+ E L+ +
Sbjct: 990 VLIHSIREIAQSHRDMEQELAHAVNASSKSM-DRVYGKPR----------TTEGLNCSFV 1038
Query: 1146 VDVTFSLKGLYDDTTAFLDEKLLRSAE--DETALQSALDAMNKEFKKLSEIDWMNPIFVP 1203
+++ + + L +T L K+ + + L SAL M+++ ++L++ W+ P
Sbjct: 1039 LEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEP 1098
Query: 1204 -EEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLW 1249
+E+S D KF + K K E+ K K S +LW
Sbjct: 1099 GDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLW 1145
Score = 35.4 bits (80), Expect = 0.35
Identities = 14/26 (53%), Positives = 15/26 (57%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIPEP 57
PPP PP PPP PP + EP EP
Sbjct: 8 PPPGPPQPPPPPPPEESSDSEPEAEP 33
Score = 34.3 bits (77), Expect = 0.78
Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 6/35 (17%)
Query: 21 AESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIP 55
A +P P PP PPPPPPP S++ PE P
Sbjct: 5 AGAPPPGPPQPPPPPPPEES------SDSEPEAEP 33
Score = 31.6 bits (70), Expect = 5.0
Identities = 14/31 (45%), Positives = 16/31 (51%)
Query: 21 AESPEPPPPWPPPPPPPAPPPAPPLLSEASP 51
A + PPP P PPPPP P + EA P
Sbjct: 3 AAAGAPPPGPPQPPPPPPPEESSDSEPEAEP 33
Score = 31.2 bits (69), Expect = 6.6
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 7 AAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPI 54
AA APP P PP P PPPPPP + P SP+ +
Sbjct: 2 AAAAGAPP---------PGPPQP-PPPPPPEESSDSEPEAEPGSPQKL 39
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 766 bits (1978), Expect = 0.0
Identities = 456/1117 (40%), Positives = 640/1117 (57%), Gaps = 109/1117 (9%)
Query: 217 ILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCH 276
I+KEG + K NSF+R K RYF ++G+ LY+A F+ +DL+ A+VAESS +N+ +
Sbjct: 10 IIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNN 69
Query: 277 SFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSH 336
SF VITP RK+ L A NRK+ME+WI +KT+Q E ++ P + GMH WY+
Sbjct: 70 SFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFE-PTQYSMDHFSGMHNWYACSHA 128
Query: 337 RTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTL-SITDDLLLPADEV 395
R +CNVCRE++ ++ + CEVCK K+H+ CA+RA+ +CKW TL SI D++ AD +
Sbjct: 129 RPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGI 188
Query: 396 NMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHR 455
MPHQW+EGN+PVS++C VC ++CGS RLQD+RCLWC + VH C+ +C +
Sbjct: 189 AMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCK 248
Query: 456 SSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQY 515
SVIPPTAL+ DG FW +C+ PLL+F+NSKSGD+QG+ FLR+FKQ
Sbjct: 249 VSVIPPTALNSIDSDG-------FWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQL 301
Query: 516 LNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIP 575
LNP+QVFDL+ GGP GL +F+ F FRILVCGGDGSV WVLS ID+ LH++CQL V+P
Sbjct: 302 LNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLP 361
Query: 576 LGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRET--PRQTPLLKGQ 633
LGTGNDLARVLGWG+ + IL ++E+AS ++LDRWSVM E PRQ
Sbjct: 362 LGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVT 421
Query: 634 VEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQI 693
+ + + +S A L+KIL + + +I + + LC V+DFV + KA+ +
Sbjct: 422 EDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKT 481
Query: 694 KQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKS-----ATEYAD--------S 740
+++ + K ++ ++L L+ L +E+ A+S+ + A E D
Sbjct: 482 TESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICG 541
Query: 741 SKADR--KPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFS 798
S DR P I + + +L +A SL+K+++ II E+A+DE++ QT + F
Sbjct: 542 STGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGF- 600
Query: 799 STFFLEDDPEDINQT------------SPRRRSRR-------------GTLSSISSL--- 830
L + E ++ P+ RS+R G+LS SS
Sbjct: 601 -VLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLP 659
Query: 831 ----KSEDLDNLN----------------------------LDHLHFTPESIR-FKEKCV 857
+ L LN D + PE++ + EKCV
Sbjct: 660 PQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCV 719
Query: 858 MNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHL 917
MNNYFGIGLDAKISLDFN +RDEHP + SR KN MWYG+LGTKELL R+Y+ LE++V L
Sbjct: 720 MNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLL 779
Query: 918 ECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQM 977
ECDG I LP+LQGI VLNI SYAGG NFWG + AP+ DD LEVVA+FGS+QM
Sbjct: 780 ECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQM 839
Query: 978 AMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDR 1037
A+SR+I L HHRIAQC V I+I G+EG+PVQVDGEAW+Q PG I+I +KN AQ LTRDR
Sbjct: 840 AVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDR 899
Query: 1038 DFENSMKMWEYKH-TEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLS 1096
FE+++K WE K E+ P L E LS+EE QM + A LI + +++
Sbjct: 900 AFESTLKSWEDKQKCELPRPPSCSL----HPEMLSEEEATQMDQFGQAAGVLIHSIREIA 955
Query: 1097 KIHQHV-SVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGL 1155
+ H+ + L +VNAS+ + D YG+ E L+ + +++ + + L
Sbjct: 956 QSHRDMEQELAHAVNASSKSM-DRVYGKPR----------TTEGLNCSFVLEMVNNFRAL 1004
Query: 1156 YDDTTAFLDEKLLRSAE--DETALQSALDAMNKEFKKLSEIDWMNPIFVP-EEKSSDTDS 1212
+T L K+ + + L SAL M+++ ++L++ W+ P +E+S D
Sbjct: 1005 RSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDL 1064
Query: 1213 RSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLW 1249
KF + K K E+ K K S +LW
Sbjct: 1065 AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLW 1101
>gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 191 bits (486), Expect = 3e-48
Identities = 119/317 (37%), Positives = 161/317 (50%), Gaps = 26/317 (8%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W R +CN+C SI L + + C +CK H CA++A C+ +T + +
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
D H WV G S +C C + Y L C+WC+ +HDDC +
Sbjct: 262 RK-----DIGVQSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAV 315
Query: 446 SKECCFRSHRSSVIPPTAL--------SDPKGDGQLVVSSDFWNLDWSSACSC------- 490
EC R ++PP+++ D K + D NL S A
Sbjct: 316 GHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTH 375
Query: 491 PLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGD 550
PLL+F+N KSG QG L KF+ LNP QVF+LLK GPE GL +FK+ RILVCGGD
Sbjct: 376 PLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGD 435
Query: 551 GSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASV 610
G+V W+L ID L +AV+PLGTGNDLAR L WG + + ++ IL +E + V
Sbjct: 436 GTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGY-EGQNLAKILKDLEMSKV 494
Query: 611 RILDRWSVMIRETPRQT 627
+DRWSV + P+QT
Sbjct: 495 VHMDRWSVEV--IPQQT 509
Score = 121 bits (304), Expect = 4e-27
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 30/204 (14%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R+++P ++NSR+KNK+WY T E + + +KLEE +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 917 LECDGETISLPNL--QGIVVLNITSYAGGINFWGSNT--------------ATTEYEA-- 958
+E G+ + L NL +GI VLNI S GG N WG AT +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 959 -------PAIDDGKLEVVAIFGSVQMAM--SRIINLHHHRIAQCHEVMITIDGEEGIPVQ 1009
P + D +LEVV + G+++M +++ N R+A+C E IT + +P+Q
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGR-RLAKCSE--ITFHTTKTLPMQ 696
Query: 1010 VDGEAWIQRPGLIKIRYKNAAQML 1033
+DGE W+Q P IKI +KN ML
Sbjct: 697 IDGEPWMQTPCTIKITHKNQMPML 720
>gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 191 bits (486), Expect = 3e-48
Identities = 119/317 (37%), Positives = 161/317 (50%), Gaps = 26/317 (8%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W R +CN+C SI L + + C +CK H CA++A C+ +T + +
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
D H WV G S +C C + Y L C+WC+ +HDDC +
Sbjct: 262 RK-----DIGVQSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAV 315
Query: 446 SKECCFRSHRSSVIPPTAL--------SDPKGDGQLVVSSDFWNLDWSSACSC------- 490
EC R ++PP+++ D K + D NL S A
Sbjct: 316 GHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTH 375
Query: 491 PLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGD 550
PLL+F+N KSG QG L KF+ LNP QVF+LLK GPE GL +FK+ RILVCGGD
Sbjct: 376 PLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGD 435
Query: 551 GSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASV 610
G+V W+L ID L +AV+PLGTGNDLAR L WG + + ++ IL +E + V
Sbjct: 436 GTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGY-EGQNLAKILKDLEMSKV 494
Query: 611 RILDRWSVMIRETPRQT 627
+DRWSV + P+QT
Sbjct: 495 VHMDRWSVEV--IPQQT 509
Score = 121 bits (304), Expect = 4e-27
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 30/204 (14%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R+++P ++NSR+KNK+WY T E + + +KLEE +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 917 LECDGETISLPNL--QGIVVLNITSYAGGINFWGSNT--------------ATTEYEA-- 958
+E G+ + L NL +GI VLNI S GG N WG AT +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 959 -------PAIDDGKLEVVAIFGSVQMAM--SRIINLHHHRIAQCHEVMITIDGEEGIPVQ 1009
P + D +LEVV + G+++M +++ N R+A+C E IT + +P+Q
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGR-RLAKCSE--ITFHTTKTLPMQ 696
Query: 1010 VDGEAWIQRPGLIKIRYKNAAQML 1033
+DGE W+Q P IKI +KN ML
Sbjct: 697 IDGEPWMQTPCTIKITHKNQMPML 720
>gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 191 bits (486), Expect = 3e-48
Identities = 119/317 (37%), Positives = 161/317 (50%), Gaps = 26/317 (8%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W R +CN+C SI L + + C +CK H CA++A C+ +T + +
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
D H WV G S +C C + Y L C+WC+ +HDDC +
Sbjct: 262 RK-----DIGVQSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAV 315
Query: 446 SKECCFRSHRSSVIPPTAL--------SDPKGDGQLVVSSDFWNLDWSSACSC------- 490
EC R ++PP+++ D K + D NL S A
Sbjct: 316 GHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTH 375
Query: 491 PLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGD 550
PLL+F+N KSG QG L KF+ LNP QVF+LLK GPE GL +FK+ RILVCGGD
Sbjct: 376 PLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGD 435
Query: 551 GSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASV 610
G+V W+L ID L +AV+PLGTGNDLAR L WG + + ++ IL +E + V
Sbjct: 436 GTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGY-EGQNLAKILKDLEMSKV 494
Query: 611 RILDRWSVMIRETPRQT 627
+DRWSV + P+QT
Sbjct: 495 VHMDRWSVEV--IPQQT 509
Score = 121 bits (304), Expect = 4e-27
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 30/204 (14%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R+++P ++NSR+KNK+WY T E + + +KLEE +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 917 LECDGETISLPNL--QGIVVLNITSYAGGINFWGSNT--------------ATTEYEA-- 958
+E G+ + L NL +GI VLNI S GG N WG AT +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 959 -------PAIDDGKLEVVAIFGSVQMAM--SRIINLHHHRIAQCHEVMITIDGEEGIPVQ 1009
P + D +LEVV + G+++M +++ N R+A+C E IT + +P+Q
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGR-RLAKCSE--ITFHTTKTLPMQ 696
Query: 1010 VDGEAWIQRPGLIKIRYKNAAQML 1033
+DGE W+Q P IKI +KN ML
Sbjct: 697 IDGEPWMQTPCTIKITHKNQMPML 720
>gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 191 bits (486), Expect = 3e-48
Identities = 119/317 (37%), Positives = 161/317 (50%), Gaps = 26/317 (8%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W R +CN+C SI L + + C +CK H CA++A C+ +T + +
Sbjct: 204 GQHMWRPKRFPRPVYCNLCESSI-GLGKQGLSCNLCKYTVHDQCAMKALP-CEVSTYAKS 261
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
D H WV G S +C C + Y L C+WC+ +HDDC +
Sbjct: 262 RK-----DIGVQSHVWVRGGCE-SGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAV 315
Query: 446 SKECCFRSHRSSVIPPTAL--------SDPKGDGQLVVSSDFWNLDWSSACSC------- 490
EC R ++PP+++ D K + D NL S A
Sbjct: 316 GHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTH 375
Query: 491 PLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGD 550
PLL+F+N KSG QG L KF+ LNP QVF+LLK GPE GL +FK+ RILVCGGD
Sbjct: 376 PLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGD 435
Query: 551 GSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASV 610
G+V W+L ID L +AV+PLGTGNDLAR L WG + + ++ IL +E + V
Sbjct: 436 GTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGY-EGQNLAKILKDLEMSKV 494
Query: 611 RILDRWSVMIRETPRQT 627
+DRWSV + P+QT
Sbjct: 495 VHMDRWSVEV--IPQQT 509
Score = 121 bits (304), Expect = 4e-27
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 30/204 (14%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R+++P ++NSR+KNK+WY T E + + +KLEE +
Sbjct: 520 IINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLT 579
Query: 917 LECDGETISLPNL--QGIVVLNITSYAGGINFWGSNT--------------ATTEYEA-- 958
+E G+ + L NL +GI VLNI S GG N WG AT +
Sbjct: 580 VEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDP 639
Query: 959 -------PAIDDGKLEVVAIFGSVQMAM--SRIINLHHHRIAQCHEVMITIDGEEGIPVQ 1009
P + D +LEVV + G+++M +++ N R+A+C E IT + +P+Q
Sbjct: 640 DILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGR-RLAKCSE--ITFHTTKTLPMQ 696
Query: 1010 VDGEAWIQRPGLIKIRYKNAAQML 1033
+DGE W+Q P IKI +KN ML
Sbjct: 697 IDGEPWMQTPCTIKITHKNQMPML 720
>gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens]
Length = 773
Score = 183 bits (464), Expect = 1e-45
Identities = 112/363 (30%), Positives = 166/363 (45%), Gaps = 59/363 (16%)
Query: 297 MEEWINIIKTIQQGEIYKIP-----AAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPAL 351
+EEWI QG + IP ENN G H W + ++ +CN+C + +
Sbjct: 216 LEEWI-------QGGMTTIPLLVLLGLENNVKDDGQHVWRLKHFNKPAYCNLCLNMLIGV 268
Query: 352 SRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQ 411
+ + C CK H C RA C I + + M H WVEGN P ++
Sbjct: 269 GKQGLCCSFCKYTVHERCVARAPPSC------IKTYVKSKRNTDVMHHYWVEGNCP--TK 320
Query: 412 CAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTAL------- 464
C CH++ YQ L C+WC T+H+ C EC + ++PPT +
Sbjct: 321 CDKCHKTVKCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQT 380
Query: 465 -----------------SDPKGDGQLVVSSDFWNLDWSSACSC--------------PLL 493
+ G Q D + +++ + PLL
Sbjct: 381 LPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLL 440
Query: 494 IFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSV 553
+F+N KSG QG RKF+ LNP QV+ L GP GL+ F++ FR+L CGGDG+V
Sbjct: 441 VFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTV 500
Query: 554 SWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRIL 613
WVL I+ + + +A++PLGTGNDLAR L WG + + ++ + IL +E ++ +L
Sbjct: 501 GWVLDCIEKANVGKHPPVAILPLGTGNDLARCLRWGGGY-EGENLMKILKDIENSTEIML 559
Query: 614 DRW 616
DRW
Sbjct: 560 DRW 562
Score = 120 bits (302), Expect = 6e-27
Identities = 71/188 (37%), Positives = 103/188 (54%), Gaps = 27/188 (14%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R++HP ++NSR+KNK WY GT E + +KL E V
Sbjct: 582 IINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVE 641
Query: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFW---------------GSNTATT----- 954
+ECDG I L N L+GI +LNI S GG N W GS+ TT
Sbjct: 642 IECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAK 701
Query: 955 --EYEAPAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVD 1011
++ + + D LEVV + G+++M + R+AQC V+I + +P+Q+D
Sbjct: 702 ELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRT--SKSLPMQID 759
Query: 1012 GEAWIQRP 1019
GE W+Q P
Sbjct: 760 GEPWMQTP 767
>gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens]
Length = 804
Score = 183 bits (464), Expect = 1e-45
Identities = 112/363 (30%), Positives = 166/363 (45%), Gaps = 59/363 (16%)
Query: 297 MEEWINIIKTIQQGEIYKIP-----AAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPAL 351
+EEWI QG + IP ENN G H W + ++ +CN+C + +
Sbjct: 216 LEEWI-------QGGMTTIPLLVLLGLENNVKDDGQHVWRLKHFNKPAYCNLCLNMLIGV 268
Query: 352 SRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQ 411
+ + C CK H C RA C I + + M H WVEGN P ++
Sbjct: 269 GKQGLCCSFCKYTVHERCVARAPPSC------IKTYVKSKRNTDVMHHYWVEGNCP--TK 320
Query: 412 CAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTAL------- 464
C CH++ YQ L C+WC T+H+ C EC + ++PPT +
Sbjct: 321 CDKCHKTVKCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQT 380
Query: 465 -----------------SDPKGDGQLVVSSDFWNLDWSSACSC--------------PLL 493
+ G Q D + +++ + PLL
Sbjct: 381 LPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLL 440
Query: 494 IFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSV 553
+F+N KSG QG RKF+ LNP QV+ L GP GL+ F++ FR+L CGGDG+V
Sbjct: 441 VFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTV 500
Query: 554 SWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRIL 613
WVL I+ + + +A++PLGTGNDLAR L WG + + ++ + IL +E ++ +L
Sbjct: 501 GWVLDCIEKANVGKHPPVAILPLGTGNDLARCLRWGGGY-EGENLMKILKDIENSTEIML 559
Query: 614 DRW 616
DRW
Sbjct: 560 DRW 562
Score = 133 bits (334), Expect = 1e-30
Identities = 79/202 (39%), Positives = 112/202 (55%), Gaps = 27/202 (13%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
++NNYF IG+DA I+ F+ R++HP ++NSR+KNK WY GT E + +KL E V
Sbjct: 582 IINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVE 641
Query: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFW---------------GSNTATT----- 954
+ECDG I L N L+GI +LNI S GG N W GS+ TT
Sbjct: 642 IECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAK 701
Query: 955 --EYEAPAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVD 1011
++ + + D LEVV + G+++M + R+AQC V+I + +P+Q+D
Sbjct: 702 ELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRT--SKSLPMQID 759
Query: 1012 GEAWIQRPGLIKIRYKNAAQML 1033
GE W+Q P IKI +KN A ML
Sbjct: 760 GEPWMQTPCTIKITHKNQAPML 781
>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
Length = 567
Score = 176 bits (447), Expect = 1e-43
Identities = 111/316 (35%), Positives = 162/316 (51%), Gaps = 34/316 (10%)
Query: 323 FLVGMHCWYSS--YSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWN 380
F H W + +S T +C VC + I C+ C ++ C +A K +
Sbjct: 55 FRKSKHGWRDTDLFSQPT-YCCVCAQHI----LQGAFCDCCGLRVDEGCLRKADKRFQCK 109
Query: 381 TLSITDDL-LLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHD 439
+ + +D +L A MPH W+ GN+P+ S C VC + CG +L D+RC+WC TVHD
Sbjct: 110 EIMLKNDTKVLDA----MPHHWIRGNVPLCSYCMVCKQQCGCQPKLCDYRCIWCQKTVHD 165
Query: 440 DCRRRFSK--ECCFRSHRSSVIPPTALS-------DPKGDGQLVVSSDFWNLDWSSACSC 490
+C + K +C F ++ +IPP+ L+ D K D +++ S W+
Sbjct: 166 ECMKNSLKNEKCDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASK--LGKQWT----- 218
Query: 491 PLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSM--FKNFARFRILVCG 548
PL+I NS+SG + G L +F+ LNP QVFD+ K P L + + R+LVCG
Sbjct: 219 PLIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCG 278
Query: 549 GDGSVSWVLSLIDAFGL--HEKC--QLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNR 604
GDG+V WVL +D + EK Q+AV+PLGTGNDL+ LGWG + +L
Sbjct: 279 GDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRN 338
Query: 605 VEQASVRILDRWSVMI 620
V +A LDRW V +
Sbjct: 339 VMEADGIKLDRWKVQV 354
Score = 133 bits (335), Expect = 9e-31
Identities = 76/209 (36%), Positives = 115/209 (55%), Gaps = 7/209 (3%)
Query: 849 SIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSY 908
++R ++ MNNYF +G DA ++L+F+ R++ P ++SR+ NK Y GTK+ L +
Sbjct: 361 NLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQEC 420
Query: 909 RKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEV 968
+ L ++V LE DGE ++LP+L+GI+VLNI + GG W Y DDG LEV
Sbjct: 421 KDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLW-EGMGDETYPLARHDDGLLEV 479
Query: 969 VAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKN 1028
V ++GS A ++ + RI Q H V + + +P+QVDGE W Q P + I +K
Sbjct: 480 VGVYGSFHCAQIQVKLANPFRIGQAHTVRLILKCSM-MPMQVDGEPWAQGPCTVTITHKT 538
Query: 1029 AAQML-----TRDRDFENSMKMWEYKHTE 1052
A ML D D ++ + K TE
Sbjct: 539 HAMMLYFSGEQTDDDISSTSDQEDIKATE 567
>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
Length = 791
Score = 176 bits (445), Expect = 2e-43
Identities = 109/308 (35%), Positives = 149/308 (48%), Gaps = 28/308 (9%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W + + +CN C + + + + C CK H C R C T
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVK-----T 324
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
+ EV M H WVEGN V +C CH+S YQ + C+WC T H C
Sbjct: 325 YSKAKRSGEV-MQHAWVEGNSSV--KCDRCHKSIKCYQSVTARHCVWCRMTFHRKCE--L 379
Query: 446 SKECCFRSHRSSVIPPTALS----DPKGD---------GQLVVSSDFWNLDWSSACSCPL 492
S C R ++ PT++ D G+ G+LV+ + PL
Sbjct: 380 STLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTH----PL 435
Query: 493 LIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGS 552
L+ +N KSG QG LRKF LNP QVF+L GGP GL+ F++ FR+L CGGDG+
Sbjct: 436 LVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGT 495
Query: 553 VSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRI 612
V W+L ID + +AV+PLGTGNDLAR L WG + + S IL +EQ+ + +
Sbjct: 496 VGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGY-EGGSLTKILKDIEQSPLVM 554
Query: 613 LDRWSVMI 620
LDRW + +
Sbjct: 555 LDRWHLEV 562
Score = 132 bits (332), Expect = 2e-30
Identities = 75/196 (38%), Positives = 108/196 (55%), Gaps = 21/196 (10%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
+MNNYF IG+DA I+ F+ R++HP ++NSR+KNK+WY GT E + +KL + +
Sbjct: 578 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 637
Query: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFWGSNTAT----------------TEYEA 958
LECDG + L N L+GI +LNI S GG N WG N ++
Sbjct: 638 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 697
Query: 959 PAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQ 1017
+ D LEVV + G+++M + R+AQC +TI + +P+QVDGE W+Q
Sbjct: 698 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC--ASVTIRTNKLLPMQVDGEPWMQ 755
Query: 1018 RPGLIKIRYKNAAQML 1033
IKI +KN A M+
Sbjct: 756 PCCTIKITHKNQAPMM 771
>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
Length = 1065
Score = 136 bits (342), Expect = 1e-31
Identities = 91/304 (29%), Positives = 133/304 (43%), Gaps = 34/304 (11%)
Query: 358 CEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSS--QCAVC 415
C VCK+ H C + K + + E + H WV QC
Sbjct: 210 CAVCKIVVHTACIEQLEKINFRCKPTFREGGSRSPRENFVRHHWVHRRRQEGKCKQCGKG 269
Query: 416 HESCGSY--QRLQDFRCLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKG 469
+ S+ + + C WC H+ + C +H + ++PPT + K
Sbjct: 270 FQQKFSFHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKK 329
Query: 470 DGQLVVSSD-------------------------FWNLDWSSACSCPLLIFINSKSGDHQ 504
+ +S+ F SS PLL+F+N KSG +Q
Sbjct: 330 PQNSLKASNRKKKRTSFKRKASKRGMEQENKGRPFVIKPISSPLMKPLLVFVNPKSGGNQ 389
Query: 505 GIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFG 564
G L+ F YLNP QVFDL + GP+ L +++ RIL CGGDG+V W+LS++D
Sbjct: 390 GTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSILDELQ 449
Query: 565 LHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETP 624
L + + V+PLGTGNDLAR L WG + + IL +VE +V LDRW++ + P
Sbjct: 450 LSPQPPVGVLPLGTGNDLARTLNWGGGYT-DEPVSKILCQVEDGTVVQLDRWNLHVERNP 508
Query: 625 RQTP 628
P
Sbjct: 509 DLPP 512
Score = 115 bits (287), Expect = 3e-25
Identities = 67/186 (36%), Positives = 102/186 (54%), Gaps = 10/186 (5%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + LQRS R L + V
Sbjct: 526 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVK 585
Query: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
+ CDG ++ P +Q IV LNI Y G WG+ ++E DDG +EV+
Sbjct: 586 VVCDGTDLT-PKIQELKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVIGF 644
Query: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
+ A+ + H R+ QC EVM+ + IP+QVDGE P +I+I +N A
Sbjct: 645 TMASLAALQ--VGGHGERLHQCREVMLLT--YKSIPMQVDGEPCRLAPAMIRISLRNQAN 700
Query: 1032 MLTRDR 1037
M+ + +
Sbjct: 701 MVQKSK 706
>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
Length = 766
Score = 135 bits (339), Expect = 3e-31
Identities = 94/308 (30%), Positives = 134/308 (43%), Gaps = 53/308 (17%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSIT 385
G H W + + +CN C + + + + C CK H C R C T
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGC-----VKT 324
Query: 386 DDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRF 445
+ EV M H WVEGN V +C CH+S YQ + C+WC T H C
Sbjct: 325 YSKAKRSGEV-MQHAWVEGNSSV--KCDRCHKSIKCYQSVTARHCVWCRMTFHRKC--EL 379
Query: 446 SKECCFRSHRSSVIPPTAL----SDPKGD---------GQLVVSSDFWNLDWSSACSCPL 492
S C R ++ PT++ D G+ G+LV+ + + PL
Sbjct: 380 STLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKI----IPTPGTHPL 435
Query: 493 LIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGS 552
L+ +N KSG QG L+ F++ FR+L CGGDG+
Sbjct: 436 LVLVNPKSGGRQG-------------------------ERLNFFRDTPDFRVLACGGDGT 470
Query: 553 VSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRI 612
V W+L ID + +AV+PLGTGNDLAR L WG + + S IL +EQ+ + +
Sbjct: 471 VGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGY-EGGSLTKILKDIEQSPLVM 529
Query: 613 LDRWSVMI 620
LDRW + +
Sbjct: 530 LDRWHLEV 537
Score = 132 bits (332), Expect = 2e-30
Identities = 75/196 (38%), Positives = 108/196 (55%), Gaps = 21/196 (10%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
+MNNYF IG+DA I+ F+ R++HP ++NSR+KNK+WY GT E + +KL + +
Sbjct: 553 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 612
Query: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFWGSNTAT----------------TEYEA 958
LECDG + L N L+GI +LNI S GG N WG N ++
Sbjct: 613 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 672
Query: 959 PAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQ 1017
+ D LEVV + G+++M + R+AQC +TI + +P+QVDGE W+Q
Sbjct: 673 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC--ASVTIRTNKLLPMQVDGEPWMQ 730
Query: 1018 RPGLIKIRYKNAAQML 1033
IKI +KN A M+
Sbjct: 731 PCCTIKITHKNQAPMM 746
>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
Length = 929
Score = 134 bits (337), Expect = 6e-31
Identities = 101/346 (29%), Positives = 143/346 (41%), Gaps = 52/346 (15%)
Query: 326 GMHCWYSS-----YSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASK---DC 377
G H W+ + + + + V R ++SR C CK+ H C + K C
Sbjct: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK--CAACKIVVHTPCIEQLEKINFRC 153
Query: 378 KWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFR-------- 429
K + + V H WV Q C +Q+ F
Sbjct: 154 KPSFRESGSRNVREPTFVR--HHWVHRRR----QDGKCRHCGKGFQQKFTFHSKEIVAIS 207
Query: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 208 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 267
Query: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 268 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 327
Query: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 328 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 387
Query: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 388 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 432
Score = 110 bits (275), Expect = 9e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
Query: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 507 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
Query: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 566 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 621
Query: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 622 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 658
>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
Length = 895
Score = 134 bits (337), Expect = 6e-31
Identities = 101/346 (29%), Positives = 143/346 (41%), Gaps = 52/346 (15%)
Query: 326 GMHCWYSS-----YSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASK---DC 377
G H W+ + + + + V R ++SR C CK+ H C + K C
Sbjct: 62 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK--CAACKIVVHTPCIEQLEKINFRC 119
Query: 378 KWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFR-------- 429
K + + V H WV Q C +Q+ F
Sbjct: 120 KPSFRESGSRNVREPTFVR--HHWVHRRR----QDGKCRHCGKGFQQKFTFHSKEIVAIS 173
Query: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 174 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 233
Query: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 234 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 293
Query: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 294 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 353
Query: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 354 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 398
Score = 110 bits (275), Expect = 9e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 413 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 472
Query: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 473 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 531
Query: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 532 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 587
Query: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 588 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 624
>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
Length = 1117
Score = 134 bits (336), Expect = 7e-31
Identities = 78/226 (34%), Positives = 107/226 (47%), Gaps = 28/226 (12%)
Query: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 396 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 455
Query: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 456 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 515
Query: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 516 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 575
Query: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 576 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 620
Score = 110 bits (275), Expect = 9e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 635 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 694
Query: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 695 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 753
Query: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 754 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 809
Query: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 810 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 846
>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
Length = 945
Score = 134 bits (336), Expect = 7e-31
Identities = 78/226 (34%), Positives = 107/226 (47%), Gaps = 28/226 (12%)
Query: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 224 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 283
Query: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 284 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 343
Query: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 344 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 403
Query: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 404 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 448
Score = 110 bits (275), Expect = 9e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 463 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 522
Query: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 523 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 581
Query: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 582 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 637
Query: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 638 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 674
>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
Length = 752
Score = 132 bits (332), Expect = 2e-30
Identities = 75/196 (38%), Positives = 108/196 (55%), Gaps = 21/196 (10%)
Query: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
+MNNYF IG+DA I+ F+ R++HP ++NSR+KNK+WY GT E + +KL + +
Sbjct: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
Query: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFWGSNTAT----------------TEYEA 958
LECDG + L N L+GI +LNI S GG N WG N ++
Sbjct: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
Query: 959 PAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQ 1017
+ D LEVV + G+++M + R+AQC +TI + +P+QVDGE W+Q
Sbjct: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC--ASVTIRTNKLLPMQVDGEPWMQ 716
Query: 1018 RPGLIKIRYKNAAQML 1033
IKI +KN A M+
Sbjct: 717 PCCTIKITHKNQAPMM 732
Score = 129 bits (325), Expect = 1e-29
Identities = 86/258 (33%), Positives = 123/258 (47%), Gaps = 42/258 (16%)
Query: 399 HQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRR-------------- 444
H W + + C CH ++ Q C +C TVH+ C R
Sbjct: 272 HAWTMKHFKKPTYCNFCHIMLMGVRK-QGLCCTYCKYTVHERCVSRNIPGCVKTYSKAKR 330
Query: 445 ---FSKECCFRSH------RSSVIPPTALS----DPKGD---------GQLVVSSDFWNL 482
F ++C + R ++ PT++ D G+ G+LV+
Sbjct: 331 SGEFHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPT 390
Query: 483 DWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARF 542
+ PLL+ +N KSG QG LRKF LNP QVF+L GGP GL+ F++ F
Sbjct: 391 PGTH----PLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDF 446
Query: 543 RILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDIL 602
R+L CGGDG+V W+L ID + +AV+PLGTGNDLAR L WG + + S IL
Sbjct: 447 RVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGY-EGGSLTKIL 505
Query: 603 NRVEQASVRILDRWSVMI 620
+EQ+ + +LDRW + +
Sbjct: 506 KDIEQSPLVMLDRWHLEV 523
Score = 36.2 bits (82), Expect = 0.20
Identities = 13/52 (25%), Positives = 20/52 (38%)
Query: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDC 377
G H W + + +CN C + + + + C CK H C R C
Sbjct: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGC 321
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 130 bits (328), Expect = 6e-30
Identities = 63/135 (46%), Positives = 88/135 (65%), Gaps = 4/135 (2%)
Query: 489 SCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCG 548
SCPLL+F+N KSG +G L F++ LNP QVFDL GGP GL +F FR+LVCG
Sbjct: 586 SCPLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCG 645
Query: 549 GDGSVSWVLSLIDAFGLHEKC---QLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRV 605
GDG+V WVL ++ C +A++PLGTGNDL RVL WGA ++ + P +L V
Sbjct: 646 GDGTVGWVLGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYS-GEDPFSVLLSV 704
Query: 606 EQASVRILDRWSVMI 620
++A ++DRW++++
Sbjct: 705 DEADAVLMDRWTILL 719
Score = 124 bits (311), Expect = 6e-28
Identities = 72/205 (35%), Positives = 116/205 (56%), Gaps = 6/205 (2%)
Query: 858 MNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHL 917
M+NY GIG+DA++SLDF+ R+E PG++ SRL NK Y +G +++ R L +++ L
Sbjct: 742 MSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRVGLQKISHS--RSLHKQIRL 799
Query: 918 ECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQM 977
+ + + + LP+++G++ +NI S+ G + WGS+ + T +E P +DDG LEVV + G V M
Sbjct: 800 QVERQEVELPSIEGLIFINIPSWGSGADLWGSD-SDTRFEKPRMDDGLLEVVGVTGVVHM 858
Query: 978 AMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDR 1037
+ RIAQ +T+ + PVQVDGE W+Q PG + I + R +
Sbjct: 859 GQVQGGLRSGIRIAQGSYFRVTL--LKATPVQVDGEPWVQAPGHMIISAAGPKVHMLR-K 915
Query: 1038 DFENSMKMWEYKHTEIQAAPQPQLD 1062
+ + + AAP P+ D
Sbjct: 916 AKQKPRRAGTTRDARADAAPAPESD 940
Score = 87.4 bits (215), Expect = 8e-17
Identities = 51/154 (33%), Positives = 70/154 (45%), Gaps = 12/154 (7%)
Query: 314 KIPAAENNPFLVGM---HCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCA 370
+IP P LV + HC+ H+ + C VCR+ + A A+ CEVC++ H C
Sbjct: 105 RIPCTSVAPSLVRVPVAHCFGPRGLHKRKFCAVCRKVLEA---PALHCEVCELHLHPDCV 161
Query: 371 LRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRC 430
A DC+ D H W EGN+P ++C VC ++CGS L RC
Sbjct: 162 PFACSDCRQCHQDGHQD------HDTHHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRC 215
Query: 431 LWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTAL 464
WC H C + EC F RS V+PP +
Sbjct: 216 EWCGVQAHSLCSAALAPECGFGRLRSLVLPPACV 249
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 105 bits (262), Expect = 3e-22
Identities = 70/196 (35%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P + EP P P P P P ++++P EP P P P E A
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323
Query: 80 EPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPEPTPEPALE 132
EPTP EPA EPAP EPAP +PAP EPAP E AP T EP+
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 133 SVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERG 192
+ EPAP T + AP EP P T+ AP E +P PAP + P T +
Sbjct: 384 TPKEPAP-TTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK- 440
Query: 193 LKTSPSPSPSPSPRTP 208
K +P+ P+P TP
Sbjct: 441 -KPAPTTPKEPAPTTP 455
Score = 100 bits (250), Expect = 7e-21
Identities = 75/212 (35%), Positives = 89/212 (41%), Gaps = 18/212 (8%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPP-PAPPLLSEASP----EPIP---EPCPELAP 63
AP P EP P P P P P PAP E +P EP P EP P
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346
Query: 64 GPCPEATSESATELYTEPTP----EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA- 118
P P A + A EP P EPA EP+P EPAP T+ AP EPA
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPTTTKEPAP 405
Query: 119 --TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
T+SAP EP+ + EPAP E AP +P P E AP E AP
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
PAP + P T + +T+P+ +P TP
Sbjct: 466 PAPTTPKEPAPTTPK--ETAPTTPKKLTPTTP 495
Score = 100 bits (248), Expect = 1e-20
Identities = 74/211 (35%), Positives = 90/211 (42%), Gaps = 19/211 (9%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + P P P P P PAP E +P EP P P P T
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP-TTK 338
Query: 72 ESATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPE 124
E A EP P +PA EPAP EPAP EP+P EPA T+SAP
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 125 PTPEPA---LESVP----EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSP 177
T EPA +S P EP+P T E AP EP P + AP E AP P
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 178 APCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP + P T + + +P+ +P TP
Sbjct: 459 APTTTKKPAPTTPK--EPAPTTPKETAPTTP 487
Score = 98.2 bits (243), Expect = 4e-20
Identities = 81/244 (33%), Positives = 95/244 (38%), Gaps = 42/244 (17%)
Query: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCP--- 59
A + AP E +P+ P P P P P P PAP E SP EP P
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 393
Query: 60 --------ELAPG-----------PCPEATSESATELYTEPTPEPATEPA----SEPAPE 96
E AP P P T E A EP P +PA EPAP
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453
Query: 97 PATEPAPEPATEPAP----EPAPEPATESAPEP-------TPEPALESVPE-PAPELTPE 144
EPAP +PAP EPAP E+AP TPE + PE PAP E
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 513
Query: 145 VAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPS 204
+AP EPTP E AP AAP PAP + P T + + +P+ +
Sbjct: 514 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETA 571
Query: 205 PRTP 208
P TP
Sbjct: 572 PTTP 575
Score = 97.1 bits (240), Expect = 1e-19
Identities = 68/204 (33%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + + P P P P P P PAP E +P EP P P P
Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 72 ESATELYTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
E A T+ P EPA ++ AP EP+P EPAP EPAP + AP
Sbjct: 387 EPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 125 PTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
EPA + EPAP T + AP EP P E AP + P AP +
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 185 PVDTRERGLKTSPSPSPSPSPRTP 208
P T L +P+ P+P TP
Sbjct: 506 PAPTTPEEL--APTTPEEPTPTTP 527
Score = 96.3 bits (238), Expect = 2e-19
Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 11/205 (5%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72
P ++PA + P+ P P P P P ++++P EP P P P E
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 73 SATELYTEPTP---EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP-- 127
A EP P + A EPAP +PAP EPAP EP + EP P
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337
Query: 128 -EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQ-CP 185
EPA + EPAP + AP EP P E AP E +P PAP + P
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 186 VDTRERG---LKTSPSPSPSPSPRT 207
T+E K++P+ PSP T
Sbjct: 398 TTTKEPAPTTTKSAPTTPKEPSPTT 422
Score = 94.0 bits (232), Expect = 8e-19
Identities = 65/199 (32%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 25 EPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPG-------PCPEATSESATEL 77
EP P P P P P +++P EP P P P T E A
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274
Query: 78 YTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
EP P EPA ++ AP EPAP +PAP EPA + EPTP E
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334
Query: 135 P---EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRER 191
P EPAP E AP +P P E AP E AP P+P + P T
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT-- 392
Query: 192 GLKTSPSPSPSPSPRTPMS 210
K++P+ + P+P T S
Sbjct: 393 -TKSAPTTTKEPAPTTTKS 410
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 16/203 (7%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P P P P P E +P EP P P P E A
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 80 EPTPEPATEPASEPAPEPA---TEPAPEPATEPAP-----------EPAPEPATESAPEP 125
EP P EP+ EPA T+ AP EPAP EP+P E AP
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430
Query: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185
EPA + +PAP E AP EP P + AP E AP AP +
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490
Query: 186 VDTRERGLKTSPSPSPSPSPRTP 208
T K +P+ P+P TP
Sbjct: 491 TPTTPE--KLAPTTPEKPAPTTP 511
Score = 92.4 bits (228), Expect = 2e-18
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 22/209 (10%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P PAP E +P EP P P P T++SA
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-TTTKSAPTTPK 299
Query: 80 EPTPEPATEPA----SEPAPEPATEPAP----EPAT---EPAPEPAPEPATESAPEPTP- 127
EP P +PA EPAP EP P EPA EPAP EPA + +P P
Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359
Query: 128 ---EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQ 183
EPA + EPAP T E +P EP P T+ AP E AP + +P
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP-TTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 184 CPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ P+P TP
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Score = 90.9 bits (224), Expect = 7e-18
Identities = 71/210 (33%), Positives = 85/210 (40%), Gaps = 16/210 (7%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEAT 70
P ++PA + P+ P P P P P P PAP E +P +P P P P
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479
Query: 71 SESAT---ELYTEPTPEPATEPASE-PAPEPATEPAPEPATEPAP----EPAPEPATESA 122
E+A + T TPE E PAP E AP EP P EPAP +A
Sbjct: 480 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 539
Query: 123 PEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL 182
P EPA + EPAP E AP E P AP E AP PAP L
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599
Query: 183 QCPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ +P TP
Sbjct: 600 -APTTTKEPTSTTCDKPAPTTPKGTAPTTP 628
Score = 87.4 bits (215), Expect = 8e-17
Identities = 67/210 (31%), Positives = 82/210 (39%), Gaps = 24/210 (11%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
AP E +PE P P P P P P A A+P EP P P P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKA------AAPNTPKEPAPTTPKEPAPTTPK 560
Query: 72 ESA--TELYTEPTPEPATEPAS--EPAPEPATEPAP---------EPATEPAPEPAPEPA 118
E A T T PT T P + EPAP +PAP EP + +PAP
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178
+AP EPA + EPAP AP EP P + AP+ E AP P
Sbjct: 621 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK---ELAPTTTKGPT 677
Query: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
P T + +T+P+ P+P TP
Sbjct: 678 STTSDKPAPTTPK--ETAPTTPKEPAPTTP 705
Score = 84.7 bits (208), Expect = 5e-16
Identities = 68/192 (35%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESATELYTEPTP---EPA 86
P P P L + P P EP P P T +SA EP P + A
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-TTIKSAPTTPKEPAPTTTKSA 255
Query: 87 TEPASEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPEPTPEPALESVPEPAPELTP 143
EPAP EPAP EPAP EPA T+SAP EPA + +PAP
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 315
Query: 144 EVAPELAPEPTPE------PVT-ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTS 196
E AP EPTP P T E AP E AP PAP + P T + + +
Sbjct: 316 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK--EPA 373
Query: 197 PSPSPSPSPRTP 208
P+ + PSP TP
Sbjct: 374 PTTTKEPSPTTP 385
Score = 84.0 bits (206), Expect = 9e-16
Identities = 67/228 (29%), Positives = 80/228 (35%), Gaps = 49/228 (21%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAP-------PLLSEASPEPIPEPCPELAPGPCPEATSE 72
P + EP P P P P AP P ++++P EP P P P E
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Query: 73 SATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAP----------------- 111
A +P P EPA EPAP +PAP EPAP
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493
Query: 112 -----------EPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
+PAP E AP EP + EPAP AP EP P E
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553
Query: 161 LAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP E AP AP T +G T+P+ P+P TP
Sbjct: 554 PAPTTPKEPAPTTPKETAP--------TTPKG--TAPTTLKEPAPTTP 591
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/223 (31%), Positives = 84/223 (37%), Gaps = 40/223 (17%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPP--APPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
T P + + P P P P P P P P L+ +PE + PE P P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK---PAPT 509
Query: 69 ATSESATELYTEPTPEPATEPA------------SEPAPEPATEPAPEPATEPAP----E 112
E A EPTP EPA EPAP EPAP EPAP E
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 569
Query: 113 PAPEPATESAPEPTPEPALESVPEPAP-ELTPEVAPELA------PEPTPEPVTELAPEF 165
AP +AP EPA + +PAP EL P E P PT T
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT------ 623
Query: 166 CPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP PAP + P T +G T+P+ P+P TP
Sbjct: 624 ----APTTPKEPAPTTPKEPAPTTPKG--TAPTTLKEPAPTTP 660
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/229 (30%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 12 APPQDGEQPAES-PEPPPPWPPPPPPPAPPP--APPLLSEASPEPIPEPCPELAPGPCPE 68
A P ++PA + P+ P P P P P P AP +P + EP P P P+
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
EL T EP + +PAP AP EPAP EPAP +AP
Sbjct: 598 -------ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650
Query: 125 PTPEPALESVPEPAP-ELTPEVAP----ELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
EPA + +PAP EL P + +P P E AP E AP PAP
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710
Query: 180 CLLQCPVDTRERGLKTSPSPSP-----SPSPRTP-MSWSRIKKILKEGP 222
+ P T + + P SP TP +S K L+ P
Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/160 (35%), Positives = 70/160 (43%), Gaps = 11/160 (6%)
Query: 57 PCPELAPGPCPEATSESATELYT---EPTPEPATEPASEPAPEPATEPAPEPATEPAPEP 113
P ++ P P+A + + T EPTP EPAS EP T P EP
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK-EP 247
Query: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEF 173
AP T+SAP EPA + EPAP E AP EP P T+ AP E AP
Sbjct: 248 APT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTT 305
Query: 174 RPSPAPCLLQCPVDT--RERGLKTSPSPSPS---PSPRTP 208
PAP + P T +E T P+P+ P+P TP
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/200 (29%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 18 EQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74
++PA + P+ P P P P P PAP +P + EP P P P+
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK------ 666
Query: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA--PEPATESAPEPTPE---- 128
EL T P + + +PAP E AP EPAP P P T P PT
Sbjct: 667 -ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVD- 187
P P + E PEL+ EPTP+ + E +P+ + + P + D
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 188 TRERGLKTSPSPSPSPSPRT 207
T ER L+T+P + + T
Sbjct: 785 TTERDLRTTPETTTAAPKMT 804
Score = 51.6 bits (122), Expect = 5e-06
Identities = 51/175 (29%), Positives = 64/175 (36%), Gaps = 23/175 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP----GPC 66
T P + P P P P P AP S S +P P E AP P
Sbjct: 642 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 67 PEATSESATELYTEPTPEPATEPASEP--APEPAT------EPAPEPATEPAPEPAPEPA 118
P + A T TP P T S P EP T E PE + EP P+ A
Sbjct: 702 PTTPKKPAPT--TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-----A 754
Query: 119 TESAPEPTPEPALESVPEPAPELT---PEVAPELAPEPTPEPVTELAPEFCPEAA 170
E++P+ P ++ PE+T + E TPE T AP+ E A
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE-TTTAAPKMTKETA 808
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/165 (31%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP-------PAPPLLSEASPEPIPEPCPEL 61
+GTAP E +P+ P P P P PAP E +P EP P
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 62 APGPCPEA-------TSESATELYT-EPT-----PEPAT-EPASEPAPEPATEPAPEPAT 107
P P TSE +T T EPT P+ +T E ++EP P+ EP
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764
Query: 108 EPAPEPA---PEPATESAPEPTPEPALESVPE---PAPELTPEVA 146
PA PE T +A + T E L + PE AP++T E A
Sbjct: 765 PTTKTPAATKPE-MTTTAKDKTTERDLRTTPETTTAAPKMTKETA 808
Score = 49.7 bits (117), Expect = 2e-05
Identities = 60/199 (30%), Positives = 73/199 (36%), Gaps = 29/199 (14%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP-EATSESATELYTEPTPEPATEPA 90
P P P+ PP E S E E + TS E T + E
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 91 SEPAPEPATEPAPEPATEPAPEPAPE-----PATESAPEPTP----EPALESVPEPAPEL 141
S A + AP P P E PA + EPTP EPA + EP P
Sbjct: 183 S------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-T 235
Query: 142 TPEVAPELAPEPTP-----EPVT--ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK 194
T + AP EP P P T E AP E AP PAP + P T +
Sbjct: 236 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 295
Query: 195 TSP-SPSPS----PSPRTP 208
T+P P+P+ P+P TP
Sbjct: 296 TTPKEPAPTTPKKPAPTTP 314
Score = 31.6 bits (70), Expect = 5.0
Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 5/82 (6%)
Query: 67 PEATSESATELYTE--PTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP- 123
P+ T+ T TE PE +P AT P P+ T+ +P ++ P
Sbjct: 849 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 908
Query: 124 --EPTPEPALESVPEPAPELTP 143
+P P + PEL P
Sbjct: 909 VRKPKTTPTPRKMTSTMPELNP 930
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 105 bits (262), Expect = 3e-22
Identities = 70/196 (35%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P + EP P P P P P ++++P EP P P P E A
Sbjct: 305 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364
Query: 80 EPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPEPTPEPALE 132
EPTP EPA EPAP EPAP +PAP EPAP E AP T EP+
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 133 SVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERG 192
+ EPAP T + AP EP P T+ AP E +P PAP + P T +
Sbjct: 425 TPKEPAP-TTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK- 481
Query: 193 LKTSPSPSPSPSPRTP 208
K +P+ P+P TP
Sbjct: 482 -KPAPTTPKEPAPTTP 496
Score = 100 bits (250), Expect = 7e-21
Identities = 75/212 (35%), Positives = 89/212 (41%), Gaps = 18/212 (8%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPP-PAPPLLSEASP----EPIP---EPCPELAP 63
AP P EP P P P P P PAP E +P EP P EP P
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387
Query: 64 GPCPEATSESATELYTEPTP----EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA- 118
P P A + A EP P EPA EP+P EPAP T+ AP EPA
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPTTTKEPAP 446
Query: 119 --TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
T+SAP EP+ + EPAP E AP +P P E AP E AP
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
PAP + P T + +T+P+ +P TP
Sbjct: 507 PAPTTPKEPAPTTPK--ETAPTTPKKLTPTTP 536
Score = 100 bits (248), Expect = 1e-20
Identities = 74/211 (35%), Positives = 90/211 (42%), Gaps = 19/211 (9%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + P P P P P PAP E +P EP P P P T
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP-TTK 379
Query: 72 ESATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPE 124
E A EP P +PA EPAP EPAP EP+P EPA T+SAP
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 125 PTPEPA---LESVP----EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSP 177
T EPA +S P EP+P T E AP EP P + AP E AP P
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 178 APCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP + P T + + +P+ +P TP
Sbjct: 500 APTTTKKPAPTTPK--EPAPTTPKETAPTTP 528
Score = 98.2 bits (243), Expect = 4e-20
Identities = 81/244 (33%), Positives = 95/244 (38%), Gaps = 42/244 (17%)
Query: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCP--- 59
A + AP E +P+ P P P P P P PAP E SP EP P
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 434
Query: 60 --------ELAPG-----------PCPEATSESATELYTEPTPEPATEPA----SEPAPE 96
E AP P P T E A EP P +PA EPAP
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494
Query: 97 PATEPAPEPATEPAP----EPAPEPATESAPEP-------TPEPALESVPE-PAPELTPE 144
EPAP +PAP EPAP E+AP TPE + PE PAP E
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 554
Query: 145 VAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPS 204
+AP EPTP E AP AAP PAP + P T + + +P+ +
Sbjct: 555 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETA 612
Query: 205 PRTP 208
P TP
Sbjct: 613 PTTP 616
Score = 97.1 bits (240), Expect = 1e-19
Identities = 68/204 (33%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + + P P P P P P PAP E +P EP P P P
Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 72 ESATELYTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
E A T+ P EPA ++ AP EP+P EPAP EPAP + AP
Sbjct: 428 EPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 125 PTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
EPA + EPAP T + AP EP P E AP + P AP +
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 185 PVDTRERGLKTSPSPSPSPSPRTP 208
P T L +P+ P+P TP
Sbjct: 547 PAPTTPEEL--APTTPEEPTPTTP 568
Score = 96.3 bits (238), Expect = 2e-19
Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 11/205 (5%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72
P ++PA + P+ P P P P P ++++P EP P P P E
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 73 SATELYTEPTP---EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP-- 127
A EP P + A EPAP +PAP EPAP EP + EP P
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378
Query: 128 -EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQ-CP 185
EPA + EPAP + AP EP P E AP E +P PAP + P
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 186 VDTRERG---LKTSPSPSPSPSPRT 207
T+E K++P+ PSP T
Sbjct: 439 TTTKEPAPTTTKSAPTTPKEPSPTT 463
Score = 94.0 bits (232), Expect = 8e-19
Identities = 65/199 (32%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 25 EPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPG-------PCPEATSESATEL 77
EP P P P P P +++P EP P P P T E A
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315
Query: 78 YTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
EP P EPA ++ AP EPAP +PAP EPA + EPTP E
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375
Query: 135 P---EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRER 191
P EPAP E AP +P P E AP E AP P+P + P T
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT-- 433
Query: 192 GLKTSPSPSPSPSPRTPMS 210
K++P+ + P+P T S
Sbjct: 434 -TKSAPTTTKEPAPTTTKS 451
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 16/203 (7%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P P P P P E +P EP P P P E A
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 80 EPTPEPATEPASEPAPEPA---TEPAPEPATEPAP-----------EPAPEPATESAPEP 125
EP P EP+ EPA T+ AP EPAP EP+P E AP
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471
Query: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185
EPA + +PAP E AP EP P + AP E AP AP +
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531
Query: 186 VDTRERGLKTSPSPSPSPSPRTP 208
T K +P+ P+P TP
Sbjct: 532 TPTTPE--KLAPTTPEKPAPTTP 552
Score = 92.4 bits (228), Expect = 2e-18
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 22/209 (10%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P PAP E +P EP P P P T++SA
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-TTTKSAPTTPK 340
Query: 80 EPTPEPATEPA----SEPAPEPATEPAP----EPAT---EPAPEPAPEPATESAPEPTP- 127
EP P +PA EPAP EP P EPA EPAP EPA + +P P
Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400
Query: 128 ---EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQ 183
EPA + EPAP T E +P EP P T+ AP E AP + +P
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP-TTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 184 CPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ P+P TP
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Score = 90.9 bits (224), Expect = 7e-18
Identities = 71/210 (33%), Positives = 85/210 (40%), Gaps = 16/210 (7%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEAT 70
P ++PA + P+ P P P P P P PAP E +P +P P P P
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520
Query: 71 SESAT---ELYTEPTPEPATEPASE-PAPEPATEPAPEPATEPAP----EPAPEPATESA 122
E+A + T TPE E PAP E AP EP P EPAP +A
Sbjct: 521 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 580
Query: 123 PEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL 182
P EPA + EPAP E AP E P AP E AP PAP L
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640
Query: 183 QCPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ +P TP
Sbjct: 641 -APTTTKEPTSTTCDKPAPTTPKGTAPTTP 669
Score = 87.4 bits (215), Expect = 8e-17
Identities = 67/210 (31%), Positives = 82/210 (39%), Gaps = 24/210 (11%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
AP E +PE P P P P P P A A+P EP P P P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKA------AAPNTPKEPAPTTPKEPAPTTPK 601
Query: 72 ESA--TELYTEPTPEPATEPAS--EPAPEPATEPAP---------EPATEPAPEPAPEPA 118
E A T T PT T P + EPAP +PAP EP + +PAP
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178
+AP EPA + EPAP AP EP P + AP+ E AP P
Sbjct: 662 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK---ELAPTTTKGPT 718
Query: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
P T + +T+P+ P+P TP
Sbjct: 719 STTSDKPAPTTPK--ETAPTTPKEPAPTTP 746
Score = 84.7 bits (208), Expect = 5e-16
Identities = 68/192 (35%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESATELYTEPTP---EPA 86
P P P L + P P EP P P T +SA EP P + A
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-TTIKSAPTTPKEPAPTTTKSA 296
Query: 87 TEPASEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPEPTPEPALESVPEPAPELTP 143
EPAP EPAP EPAP EPA T+SAP EPA + +PAP
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 356
Query: 144 EVAPELAPEPTPE------PVT-ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTS 196
E AP EPTP P T E AP E AP PAP + P T + + +
Sbjct: 357 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK--EPA 414
Query: 197 PSPSPSPSPRTP 208
P+ + PSP TP
Sbjct: 415 PTTTKEPSPTTP 426
Score = 84.0 bits (206), Expect = 9e-16
Identities = 67/228 (29%), Positives = 80/228 (35%), Gaps = 49/228 (21%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAP-------PLLSEASPEPIPEPCPELAPGPCPEATSE 72
P + EP P P P P AP P ++++P EP P P P E
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Query: 73 SATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAP----------------- 111
A +P P EPA EPAP +PAP EPAP
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534
Query: 112 -----------EPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
+PAP E AP EP + EPAP AP EP P E
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594
Query: 161 LAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP E AP AP T +G T+P+ P+P TP
Sbjct: 595 PAPTTPKEPAPTTPKETAP--------TTPKG--TAPTTLKEPAPTTP 632
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/223 (31%), Positives = 84/223 (37%), Gaps = 40/223 (17%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPP--APPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
T P + + P P P P P P P P L+ +PE + PE P P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK---PAPT 550
Query: 69 ATSESATELYTEPTPEPATEPA------------SEPAPEPATEPAPEPATEPAP----E 112
E A EPTP EPA EPAP EPAP EPAP E
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 610
Query: 113 PAPEPATESAPEPTPEPALESVPEPAP-ELTPEVAPELA------PEPTPEPVTELAPEF 165
AP +AP EPA + +PAP EL P E P PT T
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT------ 664
Query: 166 CPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP PAP + P T +G T+P+ P+P TP
Sbjct: 665 ----APTTPKEPAPTTPKEPAPTTPKG--TAPTTLKEPAPTTP 701
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/229 (30%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 12 APPQDGEQPAES-PEPPPPWPPPPPPPAPPP--APPLLSEASPEPIPEPCPELAPGPCPE 68
A P ++PA + P+ P P P P P P AP +P + EP P P P+
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
EL T EP + +PAP AP EPAP EPAP +AP
Sbjct: 639 -------ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691
Query: 125 PTPEPALESVPEPAP-ELTPEVAP----ELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
EPA + +PAP EL P + +P P E AP E AP PAP
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751
Query: 180 CLLQCPVDTRERGLKTSPSPSP-----SPSPRTP-MSWSRIKKILKEGP 222
+ P T + + P SP TP +S K L+ P
Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/160 (35%), Positives = 70/160 (43%), Gaps = 11/160 (6%)
Query: 57 PCPELAPGPCPEATSESATELYT---EPTPEPATEPASEPAPEPATEPAPEPATEPAPEP 113
P ++ P P+A + + T EPTP EPAS EP T P EP
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK-EP 288
Query: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEF 173
AP T+SAP EPA + EPAP E AP EP P T+ AP E AP
Sbjct: 289 APT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTT 346
Query: 174 RPSPAPCLLQCPVDT--RERGLKTSPSPSPS---PSPRTP 208
PAP + P T +E T P+P+ P+P TP
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/200 (29%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 18 EQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74
++PA + P+ P P P P P PAP +P + EP P P P+
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK------ 707
Query: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA--PEPATESAPEPTPE---- 128
EL T P + + +PAP E AP EPAP P P T P PT
Sbjct: 708 -ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766
Query: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVD- 187
P P + E PEL+ EPTP+ + E +P+ + + P + D
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Query: 188 TRERGLKTSPSPSPSPSPRT 207
T ER L+T+P + + T
Sbjct: 826 TTERDLRTTPETTTAAPKMT 845
Score = 51.6 bits (122), Expect = 5e-06
Identities = 51/175 (29%), Positives = 64/175 (36%), Gaps = 23/175 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP----GPC 66
T P + P P P P P AP S S +P P E AP P
Sbjct: 683 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 67 PEATSESATELYTEPTPEPATEPASEP--APEPAT------EPAPEPATEPAPEPAPEPA 118
P + A T TP P T S P EP T E PE + EP P+ A
Sbjct: 743 PTTPKKPAPT--TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-----A 795
Query: 119 TESAPEPTPEPALESVPEPAPELT---PEVAPELAPEPTPEPVTELAPEFCPEAA 170
E++P+ P ++ PE+T + E TPE T AP+ E A
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE-TTTAAPKMTKETA 849
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/165 (31%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP-------PAPPLLSEASPEPIPEPCPEL 61
+GTAP E +P+ P P P P PAP E +P EP P
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 62 APGPCPEA-------TSESATELYT-EPT-----PEPAT-EPASEPAPEPATEPAPEPAT 107
P P TSE +T T EPT P+ +T E ++EP P+ EP
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805
Query: 108 EPAPEPA---PEPATESAPEPTPEPALESVPE---PAPELTPEVA 146
PA PE T +A + T E L + PE AP++T E A
Sbjct: 806 PTTKTPAATKPE-MTTTAKDKTTERDLRTTPETTTAAPKMTKETA 849
Score = 49.7 bits (117), Expect = 2e-05
Identities = 60/199 (30%), Positives = 73/199 (36%), Gaps = 29/199 (14%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP-EATSESATELYTEPTPEPATEPA 90
P P P+ PP E S E E + TS E T + E
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 91 SEPAPEPATEPAPEPATEPAPEPAPE-----PATESAPEPTP----EPALESVPEPAPEL 141
S A + AP P P E PA + EPTP EPA + EP P
Sbjct: 224 S------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-T 276
Query: 142 TPEVAPELAPEPTP-----EPVT--ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK 194
T + AP EP P P T E AP E AP PAP + P T +
Sbjct: 277 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 336
Query: 195 TSP-SPSPS----PSPRTP 208
T+P P+P+ P+P TP
Sbjct: 337 TTPKEPAPTTPKKPAPTTP 355
Score = 31.6 bits (70), Expect = 5.0
Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 5/82 (6%)
Query: 67 PEATSESATELYTE--PTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP- 123
P+ T+ T TE PE +P AT P P+ T+ +P ++ P
Sbjct: 890 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 949
Query: 124 --EPTPEPALESVPEPAPELTP 143
+P P + PEL P
Sbjct: 950 VRKPKTTPTPRKMTSTMPELNP 971
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 105 bits (262), Expect = 3e-22
Identities = 70/196 (35%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P + EP P P P P P ++++P EP P P P E A
Sbjct: 357 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 416
Query: 80 EPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPEPTPEPALE 132
EPTP EPA EPAP EPAP +PAP EPAP E AP T EP+
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 133 SVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERG 192
+ EPAP T + AP EP P T+ AP E +P PAP + P T +
Sbjct: 477 TPKEPAP-TTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK- 533
Query: 193 LKTSPSPSPSPSPRTP 208
K +P+ P+P TP
Sbjct: 534 -KPAPTTPKEPAPTTP 548
Score = 100 bits (250), Expect = 7e-21
Identities = 75/212 (35%), Positives = 89/212 (41%), Gaps = 18/212 (8%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPP-PAPPLLSEASP----EPIP---EPCPELAP 63
AP P EP P P P P P PAP E +P EP P EP P
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 439
Query: 64 GPCPEATSESATELYTEPTP----EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA- 118
P P A + A EP P EPA EP+P EPAP T+ AP EPA
Sbjct: 440 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPTTTKEPAP 498
Query: 119 --TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
T+SAP EP+ + EPAP E AP +P P E AP E AP
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
PAP + P T + +T+P+ +P TP
Sbjct: 559 PAPTTPKEPAPTTPK--ETAPTTPKKLTPTTP 588
Score = 100 bits (248), Expect = 1e-20
Identities = 74/211 (35%), Positives = 90/211 (42%), Gaps = 19/211 (9%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + P P P P P PAP E +P EP P P P T
Sbjct: 373 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP-TTK 431
Query: 72 ESATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPE 124
E A EP P +PA EPAP EPAP EP+P EPA T+SAP
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 125 PTPEPA---LESVP----EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSP 177
T EPA +S P EP+P T E AP EP P + AP E AP P
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 178 APCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP + P T + + +P+ +P TP
Sbjct: 552 APTTTKKPAPTTPK--EPAPTTPKETAPTTP 580
Score = 98.2 bits (243), Expect = 4e-20
Identities = 81/244 (33%), Positives = 95/244 (38%), Gaps = 42/244 (17%)
Query: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCP--- 59
A + AP E +P+ P P P P P P PAP E SP EP P
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 486
Query: 60 --------ELAPG-----------PCPEATSESATELYTEPTPEPATEPA----SEPAPE 96
E AP P P T E A EP P +PA EPAP
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546
Query: 97 PATEPAPEPATEPAP----EPAPEPATESAPEP-------TPEPALESVPE-PAPELTPE 144
EPAP +PAP EPAP E+AP TPE + PE PAP E
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606
Query: 145 VAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPS 204
+AP EPTP E AP AAP PAP + P T + + +P+ +
Sbjct: 607 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETA 664
Query: 205 PRTP 208
P TP
Sbjct: 665 PTTP 668
Score = 97.1 bits (240), Expect = 1e-19
Identities = 68/204 (33%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + + P P P P P P PAP E +P EP P P P
Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 72 ESATELYTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
E A T+ P EPA ++ AP EP+P EPAP EPAP + AP
Sbjct: 480 EPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 125 PTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
EPA + EPAP T + AP EP P E AP + P AP +
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 185 PVDTRERGLKTSPSPSPSPSPRTP 208
P T L +P+ P+P TP
Sbjct: 599 PAPTTPEEL--APTTPEEPTPTTP 620
Score = 96.3 bits (238), Expect = 2e-19
Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 11/205 (5%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72
P ++PA + P+ P P P P P ++++P EP P P P E
Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370
Query: 73 SATELYTEPTP---EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP-- 127
A EP P + A EPAP +PAP EPAP EP + EP P
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430
Query: 128 -EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQ-CP 185
EPA + EPAP + AP EP P E AP E +P PAP + P
Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 186 VDTRERG---LKTSPSPSPSPSPRT 207
T+E K++P+ PSP T
Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTT 515
Score = 94.0 bits (232), Expect = 8e-19
Identities = 65/199 (32%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 25 EPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPG-------PCPEATSESATEL 77
EP P P P P P +++P EP P P P T E A
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 78 YTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
EP P EPA ++ AP EPAP +PAP EPA + EPTP E
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 135 P---EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRER 191
P EPAP E AP +P P E AP E AP P+P + P T
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT-- 485
Query: 192 GLKTSPSPSPSPSPRTPMS 210
K++P+ + P+P T S
Sbjct: 486 -TKSAPTTTKEPAPTTTKS 503
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 16/203 (7%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P P P P P E +P EP P P P E A
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 80 EPTPEPATEPASEPAPEPA---TEPAPEPATEPAP-----------EPAPEPATESAPEP 125
EP P EP+ EPA T+ AP EPAP EP+P E AP
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523
Query: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185
EPA + +PAP E AP EP P + AP E AP AP +
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583
Query: 186 VDTRERGLKTSPSPSPSPSPRTP 208
T K +P+ P+P TP
Sbjct: 584 TPTTPE--KLAPTTPEKPAPTTP 604
Score = 92.4 bits (228), Expect = 2e-18
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 22/209 (10%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P PAP E +P EP P P P T++SA
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-TTTKSAPTTPK 392
Query: 80 EPTPEPATEPA----SEPAPEPATEPAP----EPAT---EPAPEPAPEPATESAPEPTP- 127
EP P +PA EPAP EP P EPA EPAP EPA + +P P
Sbjct: 393 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452
Query: 128 ---EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQ 183
EPA + EPAP T E +P EP P T+ AP E AP + +P
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP-TTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 184 CPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ P+P TP
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540
Score = 90.9 bits (224), Expect = 7e-18
Identities = 71/210 (33%), Positives = 85/210 (40%), Gaps = 16/210 (7%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEAT 70
P ++PA + P+ P P P P P P PAP E +P +P P P P
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Query: 71 SESAT---ELYTEPTPEPATEPASE-PAPEPATEPAPEPATEPAP----EPAPEPATESA 122
E+A + T TPE E PAP E AP EP P EPAP +A
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 123 PEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL 182
P EPA + EPAP E AP E P AP E AP PAP L
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692
Query: 183 QCPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ +P TP
Sbjct: 693 -APTTTKEPTSTTCDKPAPTTPKGTAPTTP 721
Score = 87.4 bits (215), Expect = 8e-17
Identities = 67/210 (31%), Positives = 82/210 (39%), Gaps = 24/210 (11%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
AP E +PE P P P P P P A A+P EP P P P
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKA------AAPNTPKEPAPTTPKEPAPTTPK 653
Query: 72 ESA--TELYTEPTPEPATEPAS--EPAPEPATEPAP---------EPATEPAPEPAPEPA 118
E A T T PT T P + EPAP +PAP EP + +PAP
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178
+AP EPA + EPAP AP EP P + AP+ E AP P
Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK---ELAPTTTKGPT 770
Query: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
P T + +T+P+ P+P TP
Sbjct: 771 STTSDKPAPTTPK--ETAPTTPKEPAPTTP 798
Score = 84.7 bits (208), Expect = 5e-16
Identities = 68/192 (35%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESATELYTEPTP---EPA 86
P P P L + P P EP P P T +SA EP P + A
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-TTIKSAPTTPKEPAPTTTKSA 348
Query: 87 TEPASEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPEPTPEPALESVPEPAPELTP 143
EPAP EPAP EPAP EPA T+SAP EPA + +PAP
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 144 EVAPELAPEPTPE------PVT-ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTS 196
E AP EPTP P T E AP E AP PAP + P T + + +
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK--EPA 466
Query: 197 PSPSPSPSPRTP 208
P+ + PSP TP
Sbjct: 467 PTTTKEPSPTTP 478
Score = 84.0 bits (206), Expect = 9e-16
Identities = 67/228 (29%), Positives = 80/228 (35%), Gaps = 49/228 (21%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAP-------PLLSEASPEPIPEPCPELAPGPCPEATSE 72
P + EP P P P P AP P ++++P EP P P P E
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 73 SATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAP----------------- 111
A +P P EPA EPAP +PAP EPAP
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586
Query: 112 -----------EPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
+PAP E AP EP + EPAP AP EP P E
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646
Query: 161 LAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP E AP AP T +G T+P+ P+P TP
Sbjct: 647 PAPTTPKEPAPTTPKETAP--------TTPKG--TAPTTLKEPAPTTP 684
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/223 (31%), Positives = 84/223 (37%), Gaps = 40/223 (17%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPP--APPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
T P + + P P P P P P P P L+ +PE + PE P P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK---PAPT 602
Query: 69 ATSESATELYTEPTPEPATEPA------------SEPAPEPATEPAPEPATEPAP----E 112
E A EPTP EPA EPAP EPAP EPAP E
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 662
Query: 113 PAPEPATESAPEPTPEPALESVPEPAP-ELTPEVAPELA------PEPTPEPVTELAPEF 165
AP +AP EPA + +PAP EL P E P PT T
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT------ 716
Query: 166 CPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP PAP + P T +G T+P+ P+P TP
Sbjct: 717 ----APTTPKEPAPTTPKEPAPTTPKG--TAPTTLKEPAPTTP 753
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/229 (30%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 12 APPQDGEQPAES-PEPPPPWPPPPPPPAPPP--APPLLSEASPEPIPEPCPELAPGPCPE 68
A P ++PA + P+ P P P P P P AP +P + EP P P P+
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
EL T EP + +PAP AP EPAP EPAP +AP
Sbjct: 691 -------ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743
Query: 125 PTPEPALESVPEPAP-ELTPEVAP----ELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
EPA + +PAP EL P + +P P E AP E AP PAP
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 180 CLLQCPVDTRERGLKTSPSPSP-----SPSPRTP-MSWSRIKKILKEGP 222
+ P T + + P SP TP +S K L+ P
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/160 (35%), Positives = 70/160 (43%), Gaps = 11/160 (6%)
Query: 57 PCPELAPGPCPEATSESATELYT---EPTPEPATEPASEPAPEPATEPAPEPATEPAPEP 113
P ++ P P+A + + T EPTP EPAS EP T P EP
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK-EP 340
Query: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEF 173
AP T+SAP EPA + EPAP E AP EP P T+ AP E AP
Sbjct: 341 APT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTT 398
Query: 174 RPSPAPCLLQCPVDT--RERGLKTSPSPSPS---PSPRTP 208
PAP + P T +E T P+P+ P+P TP
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/200 (29%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 18 EQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74
++PA + P+ P P P P P PAP +P + EP P P P+
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK------ 759
Query: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA--PEPATESAPEPTPE---- 128
EL T P + + +PAP E AP EPAP P P T P PT
Sbjct: 760 -ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
Query: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVD- 187
P P + E PEL+ EPTP+ + E +P+ + + P + D
Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Query: 188 TRERGLKTSPSPSPSPSPRT 207
T ER L+T+P + + T
Sbjct: 878 TTERDLRTTPETTTAAPKMT 897
Score = 51.6 bits (122), Expect = 5e-06
Identities = 51/175 (29%), Positives = 64/175 (36%), Gaps = 23/175 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP----GPC 66
T P + P P P P P AP S S +P P E AP P
Sbjct: 735 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 794
Query: 67 PEATSESATELYTEPTPEPATEPASEP--APEPAT------EPAPEPATEPAPEPAPEPA 118
P + A T TP P T S P EP T E PE + EP P+ A
Sbjct: 795 PTTPKKPAPT--TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-----A 847
Query: 119 TESAPEPTPEPALESVPEPAPELT---PEVAPELAPEPTPEPVTELAPEFCPEAA 170
E++P+ P ++ PE+T + E TPE T AP+ E A
Sbjct: 848 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE-TTTAAPKMTKETA 901
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/165 (31%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP-------PAPPLLSEASPEPIPEPCPEL 61
+GTAP E +P+ P P P P PAP E +P EP P
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 62 APGPCPEA-------TSESATELYT-EPT-----PEPAT-EPASEPAPEPATEPAPEPAT 107
P P TSE +T T EPT P+ +T E ++EP P+ EP
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 108 EPAPEPA---PEPATESAPEPTPEPALESVPE---PAPELTPEVA 146
PA PE T +A + T E L + PE AP++T E A
Sbjct: 858 PTTKTPAATKPE-MTTTAKDKTTERDLRTTPETTTAAPKMTKETA 901
Score = 49.7 bits (117), Expect = 2e-05
Identities = 60/199 (30%), Positives = 73/199 (36%), Gaps = 29/199 (14%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP-EATSESATELYTEPTPEPATEPA 90
P P P+ PP E S E E + TS E T + E
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275
Query: 91 SEPAPEPATEPAPEPATEPAPEPAPE-----PATESAPEPTP----EPALESVPEPAPEL 141
S A + AP P P E PA + EPTP EPA + EP P
Sbjct: 276 S------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-T 328
Query: 142 TPEVAPELAPEPTP-----EPVT--ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK 194
T + AP EP P P T E AP E AP PAP + P T +
Sbjct: 329 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388
Query: 195 TSP-SPSPS----PSPRTP 208
T+P P+P+ P+P TP
Sbjct: 389 TTPKEPAPTTPKKPAPTTP 407
Score = 31.6 bits (70), Expect = 5.0
Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 5/82 (6%)
Query: 67 PEATSESATELYTE--PTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP- 123
P+ T+ T TE PE +P AT P P+ T+ +P ++ P
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1001
Query: 124 --EPTPEPALESVPEPAPELTP 143
+P P + PEL P
Sbjct: 1002 VRKPKTTPTPRKMTSTMPELNP 1023
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 105 bits (262), Expect = 3e-22
Identities = 70/196 (35%), Positives = 86/196 (43%), Gaps = 11/196 (5%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P + EP P P P P P ++++P EP P P P E A
Sbjct: 398 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 457
Query: 80 EPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPEPTPEPALE 132
EPTP EPA EPAP EPAP +PAP EPAP E AP T EP+
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 133 SVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERG 192
+ EPAP T + AP EP P T+ AP E +P PAP + P T +
Sbjct: 518 TPKEPAP-TTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK- 574
Query: 193 LKTSPSPSPSPSPRTP 208
K +P+ P+P TP
Sbjct: 575 -KPAPTTPKEPAPTTP 589
Score = 100 bits (250), Expect = 7e-21
Identities = 75/212 (35%), Positives = 89/212 (41%), Gaps = 18/212 (8%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPP-PAPPLLSEASP----EPIP---EPCPELAP 63
AP P EP P P P P P PAP E +P EP P EP P
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 480
Query: 64 GPCPEATSESATELYTEPTP----EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA- 118
P P A + A EP P EPA EP+P EPAP T+ AP EPA
Sbjct: 481 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPTTTKEPAP 539
Query: 119 --TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
T+SAP EP+ + EPAP E AP +P P E AP E AP
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
PAP + P T + +T+P+ +P TP
Sbjct: 600 PAPTTPKEPAPTTPK--ETAPTTPKKLTPTTP 629
Score = 100 bits (248), Expect = 1e-20
Identities = 74/211 (35%), Positives = 90/211 (42%), Gaps = 19/211 (9%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + P P P P P PAP E +P EP P P P T
Sbjct: 414 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP-TTK 472
Query: 72 ESATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPE 124
E A EP P +PA EPAP EPAP EP+P EPA T+SAP
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 125 PTPEPA---LESVP----EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSP 177
T EPA +S P EP+P T E AP EP P + AP E AP P
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 178 APCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP + P T + + +P+ +P TP
Sbjct: 593 APTTTKKPAPTTPK--EPAPTTPKETAPTTP 621
Score = 98.2 bits (243), Expect = 4e-20
Identities = 81/244 (33%), Positives = 95/244 (38%), Gaps = 42/244 (17%)
Query: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCP--- 59
A + AP E +P+ P P P P P P PAP E SP EP P
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 527
Query: 60 --------ELAPG-----------PCPEATSESATELYTEPTPEPATEPA----SEPAPE 96
E AP P P T E A EP P +PA EPAP
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587
Query: 97 PATEPAPEPATEPAP----EPAPEPATESAPEP-------TPEPALESVPE-PAPELTPE 144
EPAP +PAP EPAP E+AP TPE + PE PAP E
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647
Query: 145 VAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPS 204
+AP EPTP E AP AAP PAP + P T + + +P+ +
Sbjct: 648 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETA 705
Query: 205 PRTP 208
P TP
Sbjct: 706 PTTP 709
Score = 97.1 bits (240), Expect = 1e-19
Identities = 68/204 (33%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
P ++PA + + P P P P P P PAP E +P EP P P P
Sbjct: 461 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 72 ESATELYTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
E A T+ P EPA ++ AP EP+P EPAP EPAP + AP
Sbjct: 521 EPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 125 PTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
EPA + EPAP T + AP EP P E AP + P AP +
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 185 PVDTRERGLKTSPSPSPSPSPRTP 208
P T L +P+ P+P TP
Sbjct: 640 PAPTTPEEL--APTTPEEPTPTTP 661
Score = 96.3 bits (238), Expect = 2e-19
Identities = 66/205 (32%), Positives = 85/205 (41%), Gaps = 11/205 (5%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72
P ++PA + P+ P P P P P ++++P EP P P P E
Sbjct: 352 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411
Query: 73 SATELYTEPTP---EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP-- 127
A EP P + A EPAP +PAP EPAP EP + EP P
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471
Query: 128 -EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQ-CP 185
EPA + EPAP + AP EP P E AP E +P PAP + P
Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 186 VDTRERG---LKTSPSPSPSPSPRT 207
T+E K++P+ PSP T
Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTT 556
Score = 94.0 bits (232), Expect = 8e-19
Identities = 65/199 (32%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 25 EPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPG-------PCPEATSESATEL 77
EP P P P P P +++P EP P P P T E A
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 78 YTEPTPEPATEPA---SEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
EP P EPA ++ AP EPAP +PAP EPA + EPTP E
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 135 P---EPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRER 191
P EPAP E AP +P P E AP E AP P+P + P T
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT-- 526
Query: 192 GLKTSPSPSPSPSPRTPMS 210
K++P+ + P+P T S
Sbjct: 527 -TKSAPTTTKEPAPTTTKS 544
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 16/203 (7%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P P P P P E +P EP P P P E A
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 80 EPTPEPATEPASEPAPEPA---TEPAPEPATEPAP-----------EPAPEPATESAPEP 125
EP P EP+ EPA T+ AP EPAP EP+P E AP
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564
Query: 126 TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP 185
EPA + +PAP E AP EP P + AP E AP AP +
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624
Query: 186 VDTRERGLKTSPSPSPSPSPRTP 208
T K +P+ P+P TP
Sbjct: 625 TPTTPE--KLAPTTPEKPAPTTP 645
Score = 92.4 bits (228), Expect = 2e-18
Identities = 72/209 (34%), Positives = 87/209 (41%), Gaps = 22/209 (10%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
P EP P P PAP E +P EP P P P T++SA
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-TTTKSAPTTPK 433
Query: 80 EPTPEPATEPA----SEPAPEPATEPAP----EPAT---EPAPEPAPEPATESAPEPTP- 127
EP P +PA EPAP EP P EPA EPAP EPA + +P P
Sbjct: 434 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493
Query: 128 ---EPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP-EFRPSPAPCLLQ 183
EPA + EPAP T E +P EP P T+ AP E AP + +P
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP-TTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 184 CPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ P+P TP
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581
Score = 90.9 bits (224), Expect = 7e-18
Identities = 71/210 (33%), Positives = 85/210 (40%), Gaps = 16/210 (7%)
Query: 14 PQDGEQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEAT 70
P ++PA + P+ P P P P P P PAP E +P +P P P P
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Query: 71 SESAT---ELYTEPTPEPATEPASE-PAPEPATEPAPEPATEPAP----EPAPEPATESA 122
E+A + T TPE E PAP E AP EP P EPAP +A
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 123 PEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL 182
P EPA + EPAP E AP E P AP E AP PAP L
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733
Query: 183 QCPVDTRERGLKTSPSPSPS----PSPRTP 208
P T+E T P+P+ +P TP
Sbjct: 734 -APTTTKEPTSTTCDKPAPTTPKGTAPTTP 762
Score = 87.4 bits (215), Expect = 8e-17
Identities = 67/210 (31%), Positives = 82/210 (39%), Gaps = 24/210 (11%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATS 71
AP E +PE P P P P P P A A+P EP P P P
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKA------AAPNTPKEPAPTTPKEPAPTTPK 694
Query: 72 ESA--TELYTEPTPEPATEPAS--EPAPEPATEPAP---------EPATEPAPEPAPEPA 118
E A T T PT T P + EPAP +PAP EP + +PAP
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178
+AP EPA + EPAP AP EP P + AP+ E AP P
Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK---ELAPTTTKGPT 811
Query: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
P T + +T+P+ P+P TP
Sbjct: 812 STTSDKPAPTTPK--ETAPTTPKEPAPTTP 839
Score = 84.7 bits (208), Expect = 5e-16
Identities = 68/192 (35%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESATELYTEPTP---EPA 86
P P P L + P P EP P P T +SA EP P + A
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-TTIKSAPTTPKEPAPTTTKSA 389
Query: 87 TEPASEPAPEPATEPAPEPATEPAPEPAPEPA---TESAPEPTPEPALESVPEPAPELTP 143
EPAP EPAP EPAP EPA T+SAP EPA + +PAP
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 144 EVAPELAPEPTPE------PVT-ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTS 196
E AP EPTP P T E AP E AP PAP + P T + + +
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK--EPA 507
Query: 197 PSPSPSPSPRTP 208
P+ + PSP TP
Sbjct: 508 PTTTKEPSPTTP 519
Score = 84.0 bits (206), Expect = 9e-16
Identities = 67/228 (29%), Positives = 80/228 (35%), Gaps = 49/228 (21%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAP-------PLLSEASPEPIPEPCPELAPGPCPEATSE 72
P + EP P P P P AP P ++++P EP P P P E
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 73 SATELYTEPTPEPATEPA----SEPAPEPATEPAPEPATEPAP----------------- 111
A +P P EPA EPAP +PAP EPAP
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627
Query: 112 -----------EPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
+PAP E AP EP + EPAP AP EP P E
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687
Query: 161 LAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP E AP AP T +G T+P+ P+P TP
Sbjct: 688 PAPTTPKEPAPTTPKETAP--------TTPKG--TAPTTLKEPAPTTP 725
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/223 (31%), Positives = 84/223 (37%), Gaps = 40/223 (17%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPP--APPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
T P + + P P P P P P P P L+ +PE + PE P P
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK---PAPT 643
Query: 69 ATSESATELYTEPTPEPATEPA------------SEPAPEPATEPAPEPATEPAP----E 112
E A EPTP EPA EPAP EPAP EPAP E
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 703
Query: 113 PAPEPATESAPEPTPEPALESVPEPAP-ELTPEVAPELA------PEPTPEPVTELAPEF 165
AP +AP EPA + +PAP EL P E P PT T
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT------ 757
Query: 166 CPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
AP PAP + P T +G T+P+ P+P TP
Sbjct: 758 ----APTTPKEPAPTTPKEPAPTTPKG--TAPTTLKEPAPTTP 794
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/229 (30%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 12 APPQDGEQPAES-PEPPPPWPPPPPPPAPPP--APPLLSEASPEPIPEPCPELAPGPCPE 68
A P ++PA + P+ P P P P P P AP +P + EP P P P+
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP----EPAPEPATESAPE 124
EL T EP + +PAP AP EPAP EPAP +AP
Sbjct: 732 -------ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784
Query: 125 PTPEPALESVPEPAP-ELTPEVAP----ELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
EPA + +PAP EL P + +P P E AP E AP PAP
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 180 CLLQCPVDTRERGLKTSPSPSP-----SPSPRTP-MSWSRIKKILKEGP 222
+ P T + + P SP TP +S K L+ P
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/160 (35%), Positives = 70/160 (43%), Gaps = 11/160 (6%)
Query: 57 PCPELAPGPCPEATSESATELYT---EPTPEPATEPASEPAPEPATEPAPEPATEPAPEP 113
P ++ P P+A + + T EPTP EPAS EP T P EP
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK-EP 381
Query: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEF 173
AP T+SAP EPA + EPAP E AP EP P T+ AP E AP
Sbjct: 382 APT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTT 439
Query: 174 RPSPAPCLLQCPVDT--RERGLKTSPSPSPS---PSPRTP 208
PAP + P T +E T P+P+ P+P TP
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/200 (29%), Positives = 81/200 (40%), Gaps = 18/200 (9%)
Query: 18 EQPAES-PEPPPPWPPPPPPPAPP--PAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74
++PA + P+ P P P P P PAP +P + EP P P P+
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK------ 800
Query: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA--PEPATESAPEPTPE---- 128
EL T P + + +PAP E AP EPAP P P T P PT
Sbjct: 801 -ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
Query: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVD- 187
P P + E PEL+ EPTP+ + E +P+ + + P + D
Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Query: 188 TRERGLKTSPSPSPSPSPRT 207
T ER L+T+P + + T
Sbjct: 919 TTERDLRTTPETTTAAPKMT 938
Score = 51.6 bits (122), Expect = 5e-06
Identities = 51/175 (29%), Positives = 64/175 (36%), Gaps = 23/175 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP----GPC 66
T P + P P P P P AP S S +P P E AP P
Sbjct: 776 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 835
Query: 67 PEATSESATELYTEPTPEPATEPASEP--APEPAT------EPAPEPATEPAPEPAPEPA 118
P + A T TP P T S P EP T E PE + EP P+ A
Sbjct: 836 PTTPKKPAPT--TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-----A 888
Query: 119 TESAPEPTPEPALESVPEPAPELT---PEVAPELAPEPTPEPVTELAPEFCPEAA 170
E++P+ P ++ PE+T + E TPE T AP+ E A
Sbjct: 889 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE-TTTAAPKMTKETA 942
Score = 51.6 bits (122), Expect = 5e-06
Identities = 52/165 (31%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPP-------PAPPLLSEASPEPIPEPCPEL 61
+GTAP E +P+ P P P P PAP E +P EP P
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 62 APGPCPEA-------TSESATELYT-EPT-----PEPAT-EPASEPAPEPATEPAPEPAT 107
P P TSE +T T EPT P+ +T E ++EP P+ EP
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 108 EPAPEPA---PEPATESAPEPTPEPALESVPE---PAPELTPEVA 146
PA PE T +A + T E L + PE AP++T E A
Sbjct: 899 PTTKTPAATKPE-MTTTAKDKTTERDLRTTPETTTAAPKMTKETA 942
Score = 49.7 bits (117), Expect = 2e-05
Identities = 60/199 (30%), Positives = 73/199 (36%), Gaps = 29/199 (14%)
Query: 32 PPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP-EATSESATELYTEPTPEPATEPA 90
P P P+ PP E S E E + TS E T + E
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 316
Query: 91 SEPAPEPATEPAPEPATEPAPEPAPE-----PATESAPEPTP----EPALESVPEPAPEL 141
S A + AP P P E PA + EPTP EPA + EP P
Sbjct: 317 S------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP-T 369
Query: 142 TPEVAPELAPEPTP-----EPVT--ELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK 194
T + AP EP P P T E AP E AP PAP + P T +
Sbjct: 370 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429
Query: 195 TSP-SPSPS----PSPRTP 208
T+P P+P+ P+P TP
Sbjct: 430 TTPKEPAPTTPKKPAPTTP 448
Score = 31.6 bits (70), Expect = 5.0
Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 5/82 (6%)
Query: 67 PEATSESATELYTE--PTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP- 123
P+ T+ T TE PE +P AT P P+ T+ +P ++ P
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1042
Query: 124 --EPTPEPALESVPEPAPELTP 143
+P P + PEL P
Sbjct: 1043 VRKPKTTPTPRKMTSTMPELNP 1064
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 96.7 bits (239), Expect = 1e-19
Identities = 65/171 (38%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 24 PEPPPPWPPPPP-PPAPPPAPPLLSEASP--------EPIPE------PCPELAPGPCPE 68
P P PP P P PAPP P L+S+++P P+P P P AP P P
Sbjct: 246 PAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPL 305
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPE 128
+ SA L P P + P AP P AP PA+ P PAP S P PTP
Sbjct: 306 SVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAP----PSVPMPTPT 361
Query: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
P+ S P P L P AP P PTP P+ AP P A P P+ AP
Sbjct: 362 PS--SGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAP 410
Score = 88.6 bits (218), Expect = 3e-17
Identities = 69/232 (29%), Positives = 82/232 (35%), Gaps = 39/232 (16%)
Query: 7 AAQGTAPPQDGEQPAE----SPEPPPPWPPPPPP-----------------PAPPPAPPL 45
A GT P +G P SP P P PP P PAP P L
Sbjct: 177 ATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL 236
Query: 46 LSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEP 105
+ +P P P LAP P S L ++ P + P P A P P
Sbjct: 237 VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVP 296
Query: 106 ATEPAPEP------APEPATESAPEPTPEPALESVPEPAPEL------TPEVAPELAPEP 153
+ PAP P AP A AP P P L P P P L TP AP P
Sbjct: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP 356
Query: 154 TPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205
P P P P P F P+P P P+ T +P+P P+ +P
Sbjct: 357 MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFT------PAPTPMPAATP 402
Score = 75.1 bits (183), Expect = 4e-13
Identities = 59/193 (30%), Positives = 73/193 (37%), Gaps = 29/193 (15%)
Query: 27 PPPWPPPPPPPAPPP------APPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTE 80
PP P P PAP P APPL +P P P LAP P P A+
Sbjct: 290 PPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAA 349
Query: 81 PTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPE 140
P P P P+ P + P PA P P PAP PA P PTP PA
Sbjct: 350 PAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPA---------- 399
Query: 141 LTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSP- 199
TP P AP P ++ + F + AP + + P+ + + T P
Sbjct: 400 ATPAAIPTSAPIPASFSLSRVC----------FPAAQAPAMQKVPLSFQPGTVLTPSQPL 449
Query: 200 --SPSPSPRTPMS 210
P PS P+S
Sbjct: 450 VYIPPPSCGQPLS 462
Score = 41.6 bits (96), Expect = 0.005
Identities = 57/219 (26%), Positives = 78/219 (35%), Gaps = 39/219 (17%)
Query: 6 AAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGP 65
A + PP P+ P P PP P PA +P P+P AP P
Sbjct: 339 APMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPA------FAPTPVP------APTP 386
Query: 66 CPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP-- 123
P T PTP PA PA+ P P PA + A PA + P
Sbjct: 387 APIFT--------PAPTPMPAATPAAIPTSAPI--PASFSLSRVCFPAAQAPAMQKVPLS 436
Query: 124 -EP----TPEPALESVPEPAPELTPEVAPELAPEPTPEPVT-ELAPEFCPE-------AA 170
+P TP L +P P+ VA +T + P + + A+
Sbjct: 437 FQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLAS 496
Query: 171 PEFRPSPAPCLLQCPV--DTRERGLKTSPSPSPSPSPRT 207
PE R P + P+ D++ L+ + P SPS T
Sbjct: 497 PELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGST 535
Score = 39.3 bits (90), Expect = 0.024
Identities = 49/207 (23%), Positives = 77/207 (37%), Gaps = 24/207 (11%)
Query: 23 SPEPPPPWPPPPP---PPAPPPAPPLLSEASPEPIPEPCPELAPGPCPE--ATSESATEL 77
+P P + PPP P + P L +S +P L P A+ E +
Sbjct: 444 TPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYP 503
Query: 78 YTEPTPEPATEPASEPAPE----PATEPAPEPATEPAPEPAPEPATESA-------PEPT 126
Y P T + + E P T P+ T+PAP+ P P +++ PT
Sbjct: 504 YAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPT 563
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP---EFRPSPAPCLLQ 183
P+P L P P+ P P P T + + F P +P E + P +
Sbjct: 564 PQPLL---PAPSGSSAPP-HPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSE 619
Query: 184 CPVDTRERGLKTS-PSPSPSPSPRTPM 209
P+D + + P P+ +P P+
Sbjct: 620 MPLDLSSKSNRQKLPLPNQRKTPPMPV 646
Score = 34.3 bits (77), Expect = 0.78
Identities = 37/129 (28%), Positives = 47/129 (36%), Gaps = 11/129 (8%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPEL-----APGPCPEATSESA 74
P SP P P P A L AS + +P P P L + P A S
Sbjct: 527 PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSG 586
Query: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
TE TE T + S P E PE + P + +++S + P P
Sbjct: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL-----DLSSKSNRQKLPLPNQRKT 641
Query: 135 PEPAPELTP 143
P P P LTP
Sbjct: 642 P-PMPVLTP 649
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 94.7 bits (234), Expect = 5e-19
Identities = 63/211 (29%), Positives = 80/211 (37%), Gaps = 28/211 (13%)
Query: 23 SPEPPPPWPPPPP------PPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATE 76
+P PP P PPP PP P+PP + +P P P P + P T+ +
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 77 LYTEPTPEPATEPA----------SEPAPEPATEPAPEPATEPAPEPAPEPATESA---- 122
+ T TP P T P+ + P+P T P P T P+P P P T A
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPASTTT 1516
Query: 123 --PEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC 180
P TP P + P P TP P P P T L P P P +P P
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPS-PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575
Query: 181 LLQCPVDTRERG----LKTSPSPSPSPSPRT 207
P T T+P P+ +PSP T
Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606
Score = 94.7 bits (234), Expect = 5e-19
Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 18/195 (9%)
Query: 20 PAESPEPPPPWPPPPPP---PAPP----PAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72
P +P PPP PPP P+PP P+PP ++ +P P P P P T+
Sbjct: 1558 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP-----PTTTTTTP 1612
Query: 73 SATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALE 132
T + PT P T P S P T P+P P T P P P+ + TP P +
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT--TPSPPIT 1670
Query: 133 SVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERG 192
+ P P TP P P +T +P P + +P+ P T
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT---- 1726
Query: 193 LKTSPSPSPSPSPRT 207
T+PSP+ +PSP T
Sbjct: 1727 TMTTPSPTTTPSPPT 1741
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/225 (28%), Positives = 83/225 (36%), Gaps = 31/225 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPP------PPAPPPAPPLLSEASPEPIPEPCPELAPG 64
T PP P +P PP P PP PP P+PP + +P P P P
Sbjct: 1492 TTPP-----PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT- 1545
Query: 65 PCPEATSESATELYTEPTPEPATE----PASEPAPEPATEPAPEPATEPAPEPAPEPATE 120
P TS + T P+P P T P + P+P T P+P T P P P+
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 121 SAPEPTPEPALESVPEPAPELTPEVA-----PELAPEPTPEPVTELAPEFCPEAAPEFRP 175
+ TP P P +TP + P P P P T P P P
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665
Query: 176 SP--APCLLQCPVDTRERGLKTSPS--------PSPSPSPRTPMS 210
SP P T + T+PS PSP+ +P +P++
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710
Score = 86.3 bits (212), Expect = 2e-16
Identities = 68/247 (27%), Positives = 87/247 (35%), Gaps = 53/247 (21%)
Query: 11 TAPPQDGEQPAESPEPP---PPWPPPPPPPAPP----------PAPPLLSEASPEPIPEP 57
T PP P +P PP PPP P+PP P+PP + +P P P
Sbjct: 1446 TTPP-----PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500
Query: 58 CP-------------ELAPGPCPE-----ATSESATELYTEPTPEPATEPASEPAPEPAT 99
P L P P T+ T + PT P T P S P T
Sbjct: 1501 SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560
Query: 100 EPAPEPATEPAPEP--APEPATESAPEP------------TPEPALESVPEPAPELTPEV 145
P+P P T P P P P T + P P TP P + P P TP
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS- 1619
Query: 146 APELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCP--VDTRERGLKTSPSPSPSP 203
P P P T L P P P +P P P T + T+ +P P+
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679
Query: 204 SPRTPMS 210
+P +P++
Sbjct: 1680 TPSSPIT 1686
Score = 85.9 bits (211), Expect = 2e-16
Identities = 62/214 (28%), Positives = 80/214 (37%), Gaps = 26/214 (12%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPP------PPAPPPAPPLLSEASPEPIPEPCPELAPG 64
T PP P +P PP P PP PP P+PP + +P P P P
Sbjct: 1531 TTPP-----PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585
Query: 65 PCPEATSESATELYTEP--------TPEPATEPASEPAPEPATEPAPEPATEPAPEPAPE 116
P P + + T P TP P T P S P P T P P P+P
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP-SPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 117 PATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
P T + P PT P+ + P+P +T P PT P + + P PS
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP----PTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMS 210
P P+ T T+ +PSP P+ T S
Sbjct: 1701 PTTTP-SSPITTTTTPSSTT-TPSPPPTTMTTPS 1732
Score = 84.3 bits (207), Expect = 7e-16
Identities = 69/250 (27%), Positives = 85/250 (34%), Gaps = 56/250 (22%)
Query: 11 TAPPQDGEQP---AESPEPPPPWPPPP------PPPAPPPAPPLLSEASPEPIPEPCPEL 61
T PP P + PP P PP PPP P+PP+ + +P P P P
Sbjct: 1415 TLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPT 1474
Query: 62 APGPCPEATSESATELYTEPTPE---------PATEPAS--------EPAPEPATEPAPE 104
P T T T P P P T PAS P+P T P
Sbjct: 1475 TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP 1534
Query: 105 PATEPAP-------------------EPAPEPATESAPEP--TPEPALESVPEPAPELTP 143
P T P+P P+P P T + P P TP P + P P T
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT 1594
Query: 144 EVAPELAPEP------TPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSP 197
P P P TP P T +P P P P+ L + T+P
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651
Query: 198 SPSPSPSPRT 207
P+ +PSP T
Sbjct: 1652 PPTTTPSPPT 1661
Score = 81.3 bits (199), Expect = 6e-15
Identities = 64/212 (30%), Positives = 80/212 (37%), Gaps = 28/212 (13%)
Query: 11 TAPPQDGEQPAESPEPPPPW--PPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
T PP P + P PP PPP P+PP + +P P P P P P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTT-TPSPPTTTTTTPPPTTTPSP---PTTTPI 1626
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP------EPAPEPATESA 122
S T L PT P+ P + P P T P+P T P+P P P S
Sbjct: 1627 TPPTSTTTL--PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684
Query: 123 PEPTPEPALESVPEPAPELTPE------VAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
TP P ++ P+P TP P P+P P T P +P PS
Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP------SPTTTPS 1738
Query: 177 -PAPCLLQCPVDTRERGLKTSPSPSPSPSPRT 207
P + P T L T+P P PS +P T
Sbjct: 1739 PPTTTMTTLPPTTTSSPLTTTPLP-PSITPPT 1769
Score = 74.7 bits (182), Expect = 5e-13
Identities = 56/193 (29%), Positives = 67/193 (34%), Gaps = 35/193 (18%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPP------PPAPPPAPPLLSEASPEPIPEPCPELAPG 64
T PP P +P PP P PP PP P+PP + +P P P P
Sbjct: 1610 TTPP-----PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 65 PCPEATSESATELYTEPTPEPATEPAS----EPAPEPATEPAPEPATEPAPEPAPEPATE 120
P P T T TP P T P+S P+P T P P T P+
Sbjct: 1665 PSPPIT--------TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS 1716
Query: 121 SAPEPTPEPALESVPEPAPELTPEVAPELAPEPT----PEPVTELAPEFCPEAAPEFRP- 175
S P+P P + P P +P PT P T L P P P F P
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP---PTFSPF 1773
Query: 176 ----SPAPCLLQC 184
PC+ C
Sbjct: 1774 STTTPTTPCVPLC 1786
Score = 60.5 bits (145), Expect = 1e-08
Identities = 53/207 (25%), Positives = 68/207 (32%), Gaps = 24/207 (11%)
Query: 11 TAPPQDGEQPAESPEPPPPWP----------PPPPPPAPPPAPPLLSEASPEPIPEPCPE 60
T P E+P PP P P P P P+ + + P P P
Sbjct: 1880 TQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1939
Query: 61 LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPAT 119
P P T+ + T PTP P + P T P P P P P T
Sbjct: 1940 QTPTTTPITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996
Query: 120 ESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPA 178
+ PTP P P P T PTP P P P P+P
Sbjct: 1997 TTV-TPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPT 2050
Query: 179 PCLLQCPVDTRERGLKTSPSPSPSPSP 205
P Q P T + T+ + +P+P+P
Sbjct: 2051 PTGTQTPTTT---PITTTTTVTPTPTP 2074
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2038
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2039 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2094
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2095 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2149
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2150 TTT---PITTTTTVTPTPTP 2166
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2131 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2186
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2187 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2242 TTT---PITTTTTVTPTPTP 2258
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2223 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2278
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2279 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2333
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2334 TTT---PITTTTTVTPTPTP 2350
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2315 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2370
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2371 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2426 TTT---PITTTTTVTPTPTP 2442
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2407 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2462
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2463 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2517
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2518 TTT---PITTTTTVTPTPTP 2534
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2499 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2554
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2555 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2609
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2610 TTT---PITTTTTVTPTPTP 2626
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2591 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2646
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2647 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2701
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2702 TTT---PITTTTTVTPTPTP 2718
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2683 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2738
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2739 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2793
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2794 TTT---PITTTTTVTPTPTP 2810
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2775 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2830
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2831 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2886 TTT---PITTTTTVTPTPTP 2902
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2867 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 2922
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 2923 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 2978 TTT---PITTTTTVTPTPTP 2994
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 2959 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3014
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3070 TTT---PITTTTTVTPTPTP 3086
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3051 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3106
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3107 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3162 TTT---PITTTTTVTPTPTP 3178
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3143 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3198
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3199 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3253
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3254 TTT---PITTTTTVTPTPTP 3270
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3235 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3290
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3291 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3346 TTT---PITTTTTVTPTPTP 3362
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3327 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3382
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3383 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3438 TTT---PITTTTTVTPTPTP 3454
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3419 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3474
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3475 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3529
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3530 TTT---PITTTTTVTPTPTP 3546
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3511 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3566
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3567 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3622 TTT---PITTTTTVTPTPTP 3638
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3603 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3658
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3659 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3714 TTT---PITTTTTVTPTPTP 3730
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3695 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3750
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3751 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3806 TTT---PITTTTTVTPTPTP 3822
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3787 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3842
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3843 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3898 TTT---PITTTTTVTPTPTP 3914
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3879 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 3934
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 3935 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 3990 TTT---PITTTTTVTPTPTP 4006
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 3971 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 4026
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4081
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 4082 TTT---PITTTTTVTPTPTP 4098
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 17/200 (8%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 4063 ITTTTTVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPT 4118
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPAPCLLQCP 185
P P P P T PTP P P P P+P P Q P
Sbjct: 4119 PTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4173
Query: 186 VDTRERGLKTSPSPSPSPSP 205
T + T+ + +P+P+P
Sbjct: 4174 TTT---PITTTTTVTPTPTP 4190
Score = 57.8 bits (138), Expect = 7e-08
Identities = 43/163 (26%), Positives = 60/163 (36%), Gaps = 22/163 (13%)
Query: 57 PCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAP----- 111
P + P P T+ S PT P + P+P T P P T P+P
Sbjct: 1391 PMDKCITTPSPPTTTPSPP-----PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT 1445
Query: 112 -------EPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPE 164
P+P +T + P PT P+ + P TP +P TP P T +P
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP--SPPTTTTTTPPPTTTPSP- 1502
Query: 165 FCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRT 207
P P P+ L + T+P P+ +PSP T
Sbjct: 1503 --PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT 1543
Score = 56.2 bits (134), Expect = 2e-07
Identities = 41/130 (31%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 79 TEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPA 138
T P+P P T P+ P P + P T P+P T P TP P + + P
Sbjct: 1397 TTPSP-PTTTPS----PPPTSTTTLPPTTTPSPPTT--TTTTPPPTTTPSPPITTTTTPP 1449
Query: 139 PELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPS 198
P TP +P ++ TP P T +P + P PSP P T T+PS
Sbjct: 1450 PTTTP--SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT------TTPS 1501
Query: 199 PSPSPSPRTP 208
P P+ +P TP
Sbjct: 1502 P-PTTTPITP 1510
Score = 54.3 bits (129), Expect = 7e-07
Identities = 58/230 (25%), Positives = 71/230 (30%), Gaps = 40/230 (17%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P P
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPAT-EPAPEPATEPAPEPAPEPATESAPEPT 126
T+ + T PTP P + P T P P P P P T + PT
Sbjct: 4132 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PT 4187
Query: 127 PEPALESVPEPAPELTPEVAPELAPEPTPE------------PVTE-------LAPEF-C 166
P P P T +A P PE P+TE L P
Sbjct: 4188 PTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247
Query: 167 PEAAPEFRP------------SPAPCLLQCPVDTRERGLKTSPSPSPSPS 204
AP P SP P P T RG T S +P+PS
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPS 4297
Score = 51.2 bits (121), Expect = 6e-06
Identities = 59/255 (23%), Positives = 84/255 (32%), Gaps = 61/255 (23%)
Query: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPA---PPPAPPLLSEASPEPIPEPCPELAPGPCP 67
T P + P +P P P P P P+ + + P P P P
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH 4200
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPATE---------PAPE------PATEPAPE 112
+T+ A + P PE +T S P TE PA E P+T AP
Sbjct: 4201 TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 4260
Query: 113 P-------APEPATESAPEPTPEPALESVPEPAP-ELTPEVAPELAPEPTPEPVTELAPE 164
+P P+T ++P TP + AP T + A PTP P++ P
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS--TPS 4318
Query: 165 FCPEAAPEFRPSPAP-------------------------------CLLQCPVDTRERGL 193
RP P+ C L C ++
Sbjct: 4319 IIRTTG--LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSC 4376
Query: 194 KTSPSPSPSPSPRTP 208
++PSP+P+PS TP
Sbjct: 4377 PSTPSPTPTPSKSTP 4391
Score = 37.4 bits (85), Expect = 0.092
Identities = 52/240 (21%), Positives = 72/240 (30%), Gaps = 51/240 (21%)
Query: 8 AQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP 67
++ T+ P S PP PP+ P AP S P PG
Sbjct: 4224 SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPT 4283
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAP------------ 115
T+ ++ T T + T A P P P + P+ T P P+
Sbjct: 4284 RGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYY 4343
Query: 116 EPATE-----------------------------SAPEPTPEPALESVPEPA-PELTPEV 145
P E S P PTP P+ +S P P+ P TP
Sbjct: 4344 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPS-KSTPTPSKPSSTPS- 4401
Query: 146 APELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLL-QCPVDTRERGLKTSPSPSPSPS 204
+PTP P+F P C + C + +K P P P+
Sbjct: 4402 ------KPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPT 4455
Score = 31.6 bits (70), Expect = 5.0
Identities = 19/70 (27%), Positives = 26/70 (37%), Gaps = 6/70 (8%)
Query: 141 LTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPS 200
+T P P P P T L P P +P P P T T+ +P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT------TTTTPP 1449
Query: 201 PSPSPRTPMS 210
P+ +P P+S
Sbjct: 1450 PTTTPSPPIS 1459
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 91.7 bits (226), Expect = 4e-18
Identities = 72/246 (29%), Positives = 97/246 (39%), Gaps = 57/246 (23%)
Query: 14 PQDGEQPAESPEPPPPWP---------------------PPPP-------------PPAP 39
P +G P P PPPP P PPPP PP P
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763
Query: 40 PPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPAT 99
PP PP+ + P+ P+P + P P T PTP P PA + PA+
Sbjct: 764 PPPPPIPAPLPPQAPPKPLVTI-PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Query: 100 EPAPEPATEPAPEPAPE-PATES-APEPTPEPALESVPEPAPELTPEVAPELAPEPTP-- 155
P P T P P P P P +S +P P P P P + ++A + P PTP
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL-----SPVPSVVKQIASQFPPPPTPPA 877
Query: 156 ------EPV-TELAPEFCP--EAAPEFRPS----PAPCLLQCPVDTRERGLKTSPSPSPS 202
+PV +AP+ P +A P+++PS P+P P ++ PSP P+
Sbjct: 878 MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937
Query: 203 PSPRTP 208
P P P
Sbjct: 938 PPPPPP 943
Score = 84.7 bits (208), Expect = 5e-16
Identities = 73/254 (28%), Positives = 94/254 (37%), Gaps = 46/254 (18%)
Query: 14 PQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASP------------------EPIP 55
P QP+ PPPP PPPPPPP PPP PPL S+++P +
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNAS 677
Query: 56 EPCPELAPGPCPEATSESATE----------LYTEPTPEPATEPAS-----EPAPEPATE 100
+ L P P + + + P P P P S +PAP +
Sbjct: 678 QHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737
Query: 101 P---APEP---------ATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPE 148
P AP P T+ AP P P AP P P V PAP T VAP
Sbjct: 738 PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPV 797
Query: 149 LAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
+ P P + P A P P+P PV + S P PSP +P
Sbjct: 798 VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Query: 209 MSWSRIKKILKEGP 222
+ S +K+I + P
Sbjct: 858 VP-SVVKQIASQFP 870
Score = 74.3 bits (181), Expect = 7e-13
Identities = 56/191 (29%), Positives = 75/191 (39%), Gaps = 18/191 (9%)
Query: 26 PPPPWPPPPPPPAPPPAP-PLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPE 84
PP PPPPPP PPP P +++ P P P+ + P P + + T+ P
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ--VQHITQVAPP 761
Query: 85 PATEPASEPAPEPATEPAPEPATEPAPEP----APEPATESAPEPTPE--PALESVPEPA 138
P PAP P P T PAP AP + P PTP PA + PA
Sbjct: 762 TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821
Query: 139 PELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPS 198
+ P +P P P P P FC +P P+P L P ++ + P
Sbjct: 822 SYIPP--SPPTPPVPVPPPTLPKQQSFCA------KPPPSP-LSPVPSVVKQIASQFPPP 872
Query: 199 PSPSPSPRTPM 209
P+P P+
Sbjct: 873 PTPPAMESQPL 883
Score = 70.5 bits (171), Expect = 1e-11
Identities = 65/250 (26%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 5 AAAAQGTAP-PQDGEQPAESPEPPPPWPPPPPP-PAPPPAPPLLSEASPEPIPEPCPELA 62
AA T P P +QPA PP PP PP P PPP P +P P P
Sbjct: 801 AAPPTPTPPVPPAKKQPAFPASYIPP-SPPTPPVPVPPPTLPKQQSFCAKPPPSPL---- 855
Query: 63 PGPCPEATSESATELYTEPTP-------------------------EPATEPASEPAPEP 97
P P + A++ PTP +P +P+S P P P
Sbjct: 856 -SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914
Query: 98 ATEPAPEPAT--EPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAP-ELAPEPT 154
P P ++ P P P+P PA P PT P + P + + +P P PT
Sbjct: 915 DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT 974
Query: 155 PEPVTELAPEFCPEAAPEFRPSPAPCLLQC--PVDTRERGLKTSPSPSPSPSP-RTPMSW 211
P+ + + E RPS + + P ++ +T P P+ P P + +S
Sbjct: 975 PQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG 1034
Query: 212 SRIKKILKEG 221
+ +L++G
Sbjct: 1035 VNLPGVLQQG 1044
Score = 58.9 bits (141), Expect = 3e-08
Identities = 59/226 (26%), Positives = 85/226 (37%), Gaps = 28/226 (12%)
Query: 15 QDGEQPAESP--EPPPP-----WPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCP 67
Q P SP PPPP +PPPPP P P P PP P P P P+ + P
Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP------PPPTASPTPDKSGSP-G 957
Query: 68 EATSESATELYTEPTPEP-------ATEPASEPAPE-PATEPAPEPATEPAPEPAPEPAT 119
+ TS++++ +P P P ++ A P P+ P+ + T PA +P T
Sbjct: 958 KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET 1017
Query: 120 ESAPEPTPEPA---LESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176
P P+P L V P L AP + + P + +F P
Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPG-VLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPP 1076
Query: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGP 222
P L P + SP + P WS++ +K+ P
Sbjct: 1077 PPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS--VKKAP 1120
Score = 57.0 bits (136), Expect = 1e-07
Identities = 52/208 (25%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 9 QGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPE 68
+GT + + ES P PP P P P + P+P P P P P P
Sbjct: 583 RGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP- 641
Query: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPE 128
P P P S P+ A + +T + A + + PTP
Sbjct: 642 -----------PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP- 689
Query: 129 PALESVPEPAPELTPE---VAPELAPEPTPEP---VTELAPEFCPEAAPEFRPSPAPCLL 182
P ++S L P V P P P P P + +L P C + P+F P P +
Sbjct: 690 PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749
Query: 183 QCPVDTRERGLKTSPSPSPSPSPRTPMS 210
+ T P P P P+P P +
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQA 777
Score = 36.2 bits (82), Expect = 0.20
Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 13/159 (8%)
Query: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYT 79
PAES P PPP P P L P + + C +S E +
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPS 1066
Query: 80 EPT------PEPATEPASEPAPEPAT---EPAPEPA-TEPAPEPAPEPATESAPEPTPEP 129
P+ P P TE P PA +P+ A P P+ + + + AP PT
Sbjct: 1067 PPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPK 1126
Query: 130 ALESVPEPAPELT--PEVAPELAPEPT-PEPVTELAPEF 165
+S E++ P +A + PT P+ + P F
Sbjct: 1127 RNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGF 1165
Score = 32.7 bits (73), Expect = 2.3
Identities = 36/149 (24%), Positives = 56/149 (37%), Gaps = 24/149 (16%)
Query: 12 APPQDGEQPAESPEPPPPWPPPPPPPAPPPA------PPLLSEASPEPIPEPCPELAPGP 65
+PP D + P PPPP P PP PA P ++ +P+P + P
Sbjct: 1066 SPPSDSDFP-----PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP 1120
Query: 66 CP------EATSESATELYTEPT-----PEPATEPASEPAPEPA--TEPAPEPATEPAPE 112
P ++T + E+ +PT P+ T P S + +P + +
Sbjct: 1121 PPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITR 1180
Query: 113 PAPEPATESAPEPTPEPALESVPEPAPEL 141
+ S EPT ++P P PEL
Sbjct: 1181 HGSLSSRMSRAEPTATMDDMALPPPPPEL 1209
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 5e-17
Identities = 52/131 (39%), Positives = 62/131 (47%), Gaps = 17/131 (12%)
Query: 3 RGAAAAQGTAPPQDGEQPA-----ESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEP 57
R A A +PP + + E+PE P P P P PPP P L +P P P P
Sbjct: 96 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVL----APAPAPAP 151
Query: 58 CPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEP 117
P AP P A + A P PA PA PAP P PAP PA PAP PAP P
Sbjct: 152 APVAAPVAAPVAVAVLA--------PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 203
Query: 118 ATESAPEPTPE 128
A ++AP+ + E
Sbjct: 204 APDAAPQESAE 214
Score = 70.9 bits (172), Expect = 8e-12
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 12/132 (9%)
Query: 41 PAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATE 100
P P ++ A P+ EP E G E+ +L + P P PA+ P P PA
Sbjct: 95 PRPVAVAVAVSPPL-EPAAESLDG-----LEEAPEQLPSVPVPAPASTPPPVPVLAPAPA 148
Query: 101 PAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
PAP P P P AP P P PA P PAP P AP AP P P P
Sbjct: 149 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPA----PAPAPVAAPAPAP--APAPAPAPAPA 202
Query: 161 LAPEFCPEAAPE 172
AP+ P+ + E
Sbjct: 203 PAPDAAPQESAE 214
Score = 69.7 bits (169), Expect = 2e-11
Identities = 44/107 (41%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 102 APEP-ATEPAPEPAPEPATESAP--EPTPEPALESVPEPAPELTPEVAPELAPEPTPEPV 158
AP P A A P EPA ES E PE L SVP PAP TP P LAP P P P
Sbjct: 94 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPAPA 152
Query: 159 TELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205
AP P A P+PAP P +P+P+P+P+P
Sbjct: 153 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 199
Score = 69.3 bits (168), Expect = 2e-11
Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 50 SPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEP 109
+P P+ +A P E +ES L P P S P P PA+ P P P P
Sbjct: 94 APRPV---AVAVAVSPPLEPAAESLDGLEEAPEQLP-----SVPVPAPASTPPPVPVLAP 145
Query: 110 APEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEA 169
AP PAP P +AP P P PAP AP P P P AP P
Sbjct: 146 APAPAPAPV--AAPVAAPVAVAVLAPAPAP----------APAPAPAPAPVAAPAPAPAP 193
Query: 170 APEFRPSPAPCLLQCPVDTRERG 192
AP P+PAP P ++ E+G
Sbjct: 194 APAPAPAPAPAPDAAPQESAEQG 216
Score = 60.5 bits (145), Expect = 1e-08
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 10/141 (7%)
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP 127
E S+S Y E P P A A P EPA E E APE P
Sbjct: 70 EVDSDSVPAFYRETVQVGRCRLLLAPRPV-AVAVAVSPPLEPAAESLD--GLEEAPEQLP 126
Query: 128 E---PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
PA S P P P L P AP AP P PV AP AP P+PAP
Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAP--APAPVAAPVA--APVAVAVLAPAPAPAPAPAPAPA 182
Query: 185 PVDTRERGLKTSPSPSPSPSP 205
PV +P+P+P+P+P
Sbjct: 183 PVAAPAPAPAPAPAPAPAPAP 203
Score = 52.4 bits (124), Expect = 3e-06
Identities = 48/174 (27%), Positives = 58/174 (33%), Gaps = 41/174 (23%)
Query: 7 AAQGTAPPQDGEQPAESPEPPPPWPPPPPP-------PAPPPAPPLLSEASPEPIPEPCP 59
A T PP PA +P P P P P PAP PAP +P P P P
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP------APAPAPAPVA 185
Query: 60 ELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEP-------APEPATE---- 108
AP P P P P PA PA + AP+ + E EP +
Sbjct: 186 APAPAPAP------------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHS 233
Query: 109 -----PAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEP 157
PA A A +A + P + PE + P P P P
Sbjct: 234 GISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 287
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 20 PAESPEPPP-PWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELY 78
PA +P P P P P P PAP PAP +P+ P+ E A +L+
Sbjct: 173 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 232
Query: 79 TEPTPEPATEPASEPAPEPATEPAPEPATE----PAPEPAPEPATESAPEPTPEPA 130
+ + PA A+ A A + P APE ++ P P P P+
Sbjct: 233 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPS 288
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 5e-17
Identities = 52/131 (39%), Positives = 62/131 (47%), Gaps = 17/131 (12%)
Query: 3 RGAAAAQGTAPPQDGEQPA-----ESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEP 57
R A A +PP + + E+PE P P P P PPP P L +P P P P
Sbjct: 96 RPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVL----APAPAPAP 151
Query: 58 CPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEP 117
P AP P A + A P PA PA PAP P PAP PA PAP PAP P
Sbjct: 152 APVAAPVAAPVAVAVLA--------PAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAP 203
Query: 118 ATESAPEPTPE 128
A ++AP+ + E
Sbjct: 204 APDAAPQESAE 214
Score = 70.9 bits (172), Expect = 8e-12
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 12/132 (9%)
Query: 41 PAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATE 100
P P ++ A P+ EP E G E+ +L + P P PA+ P P PA
Sbjct: 95 PRPVAVAVAVSPPL-EPAAESLDG-----LEEAPEQLPSVPVPAPASTPPPVPVLAPAPA 148
Query: 101 PAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
PAP P P P AP P P PA P PAP P AP AP P P P
Sbjct: 149 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPA----PAPAPVAAPAPAP--APAPAPAPAPA 202
Query: 161 LAPEFCPEAAPE 172
AP+ P+ + E
Sbjct: 203 PAPDAAPQESAE 214
Score = 69.7 bits (169), Expect = 2e-11
Identities = 44/107 (41%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 102 APEP-ATEPAPEPAPEPATESAP--EPTPEPALESVPEPAPELTPEVAPELAPEPTPEPV 158
AP P A A P EPA ES E PE L SVP PAP TP P LAP P P P
Sbjct: 94 APRPVAVAVAVSPPLEPAAESLDGLEEAPEQ-LPSVPVPAPASTPPPVPVLAPAPAPAPA 152
Query: 159 TELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205
AP P A P+PAP P +P+P+P+P+P
Sbjct: 153 PVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAP 199
Score = 69.3 bits (168), Expect = 2e-11
Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 50 SPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEP 109
+P P+ +A P E +ES L P P S P P PA+ P P P P
Sbjct: 94 APRPV---AVAVAVSPPLEPAAESLDGLEEAPEQLP-----SVPVPAPASTPPPVPVLAP 145
Query: 110 APEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEA 169
AP PAP P +AP P P PAP AP P P P AP P
Sbjct: 146 APAPAPAPV--AAPVAAPVAVAVLAPAPAP----------APAPAPAPAPVAAPAPAPAP 193
Query: 170 APEFRPSPAPCLLQCPVDTRERG 192
AP P+PAP P ++ E+G
Sbjct: 194 APAPAPAPAPAPDAAPQESAEQG 216
Score = 60.5 bits (145), Expect = 1e-08
Identities = 49/141 (34%), Positives = 56/141 (39%), Gaps = 10/141 (7%)
Query: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTP 127
E S+S Y E P P A A P EPA E E APE P
Sbjct: 70 EVDSDSVPAFYRETVQVGRCRLLLAPRPV-AVAVAVSPPLEPAAESLD--GLEEAPEQLP 126
Query: 128 E---PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQC 184
PA S P P P L P AP AP P PV AP AP P+PAP
Sbjct: 127 SVPVPAPASTPPPVPVLAPAPAP--APAPVAAPVA--APVAVAVLAPAPAPAPAPAPAPA 182
Query: 185 PVDTRERGLKTSPSPSPSPSP 205
PV +P+P+P+P+P
Sbjct: 183 PVAAPAPAPAPAPAPAPAPAP 203
Score = 52.4 bits (124), Expect = 3e-06
Identities = 48/174 (27%), Positives = 58/174 (33%), Gaps = 41/174 (23%)
Query: 7 AAQGTAPPQDGEQPAESPEPPPPWPPPPPP-------PAPPPAPPLLSEASPEPIPEPCP 59
A T PP PA +P P P P P PAP PAP +P P P P
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAP------APAPAPAPVA 185
Query: 60 ELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEP-------APEPATE---- 108
AP P P P P PA PA + AP+ + E EP +
Sbjct: 186 APAPAPAP------------APAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHS 233
Query: 109 -----PAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEP 157
PA A A +A + P + PE + P P P P
Sbjct: 234 GISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 287
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 20 PAESPEPPP-PWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELY 78
PA +P P P P P P PAP PAP +P+ P+ E A +L+
Sbjct: 173 PAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLH 232
Query: 79 TEPTPEPATEPASEPAPEPATEPAPEPATE----PAPEPAPEPATESAPEPTPEPA 130
+ + PA A+ A A + P APE ++ P P P P+
Sbjct: 233 SGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPS 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,134,553
Number of Sequences: 37866
Number of extensions: 3822208
Number of successful extensions: 131899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1421
Number of HSP's successfully gapped in prelim test: 1674
Number of HSP's that attempted gapping in prelim test: 30825
Number of HSP's gapped (non-prelim): 34587
length of query: 1271
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1157
effective length of database: 13,930,794
effective search space: 16117928658
effective search space used: 16117928658
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.