Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 61742823
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61742823 disrupted in schizophrenia 1 isoform L [Homo
sapiens]
(854 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens] 1704 0.0
gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens] 1644 0.0
gi|61742829 disrupted in schizophrenia 1 isoform S [Homo sapiens] 1318 0.0
gi|61742827 disrupted in schizophrenia 1 isoform Es [Homo sapiens] 720 0.0
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 63 1e-09
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 59 1e-08
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 59 2e-08
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 57 7e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 55 2e-07
gi|55770834 centromere protein F [Homo sapiens] 55 2e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 54 6e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 54 6e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 54 8e-07
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 53 1e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 52 3e-06
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 51 4e-06
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 51 4e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 51 5e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 50 7e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 7e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 7e-06
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 50 7e-06
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 50 1e-05
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 50 1e-05
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 50 1e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 50 1e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 50 1e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 50 1e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 50 1e-05
gi|58530840 desmoplakin isoform I [Homo sapiens] 49 2e-05
>gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]
Length = 854
Score = 1704 bits (4413), Expect = 0.0
Identities = 854/854 (100%), Positives = 854/854 (100%)
Query: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
Query: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
Query: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
Sbjct: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
Query: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
Sbjct: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
Query: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
Sbjct: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
Query: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
Sbjct: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
Query: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
Sbjct: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
Query: 661 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
Sbjct: 661 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
Query: 721 QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE 780
QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE
Sbjct: 721 QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE 780
Query: 781 KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA 840
KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA
Sbjct: 781 KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA 840
Query: 841 AASCMTAGVHEAQA 854
AASCMTAGVHEAQA
Sbjct: 841 AASCMTAGVHEAQA 854
>gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens]
Length = 832
Score = 1644 bits (4257), Expect = 0.0
Identities = 832/854 (97%), Positives = 832/854 (97%), Gaps = 22/854 (2%)
Query: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
Query: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
Query: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
Sbjct: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
Query: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
Sbjct: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
Query: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
Sbjct: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
Query: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
Sbjct: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
Query: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
Sbjct: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
Query: 661 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
Sbjct: 661 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
Query: 721 QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE 780
QMDDLEGAAPPIPPRLHSEDKRKTPLK ESYILSAELGE
Sbjct: 721 QMDDLEGAAPPIPPRLHSEDKRKTPLK----------------------ESYILSAELGE 758
Query: 781 KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA 840
KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA
Sbjct: 759 KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA 818
Query: 841 AASCMTAGVHEAQA 854
AASCMTAGVHEAQA
Sbjct: 819 AASCMTAGVHEAQA 832
>gi|61742829 disrupted in schizophrenia 1 isoform S [Homo sapiens]
Length = 678
Score = 1318 bits (3411), Expect = 0.0
Identities = 660/660 (100%), Positives = 660/660 (100%)
Query: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
Query: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
Query: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
Sbjct: 361 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 420
Query: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
Sbjct: 421 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 480
Query: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
Sbjct: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
Query: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
Sbjct: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
Query: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
Sbjct: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
>gi|61742827 disrupted in schizophrenia 1 isoform Es [Homo sapiens]
Length = 369
Score = 720 bits (1859), Expect = 0.0
Identities = 350/355 (98%), Positives = 352/355 (99%)
Query: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
Query: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL 355
SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQME+ + L
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIAL 355
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 63.2 bits (152), Expect = 1e-09
Identities = 185/822 (22%), Positives = 323/822 (39%), Gaps = 169/822 (20%)
Query: 145 QEFAAMDSSE------TLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPPT 198
QE AA+++ + TL +A SD V+ +GS +A+ +SN G + P+
Sbjct: 436 QEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD-ASNGSLRGLSGQRTPS 494
Query: 199 PPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPS-----------------REAESHCQS 241
PP S G + RG + C S ++ ++
Sbjct: 495 PPRRSSP----------GRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEA 544
Query: 242 PQE-MGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
Q+ +G L + R L L + + QA ++ R + + S ++
Sbjct: 545 SQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAM-QAHEDAQREVQRLRSANELLSR 603
Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 360
S+L AHS ++ E + ++ Q E+ R +L++
Sbjct: 604 EKSNL-----------------AHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEE 646
Query: 361 QEDAVENDD--YDKAETLQQRLEDLEQEKISLHFQLPSRQPALS------SFLGHLAAQV 412
QEDAV++ + E ++LE LE ++ L +L + ALS L A+V
Sbjct: 647 QEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV 706
Query: 413 QAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEK-------QQL 465
AL + + + + T LR E E + QDSL + L Q+K QL
Sbjct: 707 AEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVAQL 762
Query: 466 QKEIEALQARMFVLE-----AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLS-------L 513
++E ALQ R E A+++Q R E EQ++ QG + + V + + L
Sbjct: 763 EEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQL 822
Query: 514 GQLQEVSKALQDTLASAGQ--IPFHAEPPETIRSLQERIKSLNLSLKE----------IT 561
L+ LQ+ LA + E + R Q ++++L + +E +
Sbjct: 823 PTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLA 882
Query: 562 TKVCMSEKFCSTLRKKVNDIETQLPAL-------------LEAKMHAI--SGNHFWTAKD 606
++ +E+ TL ++ + + AL LEA+ + G AK+
Sbjct: 883 VQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKE 942
Query: 607 -LTEEIRSL------TSEREGLE-GLLSKLLVLSSRNV-----KKLGSVKEDYNRLRREV 653
LT E+ L T E+ L+ L+++ LV + R ++ + +ED RL+RE
Sbjct: 943 TLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRE- 1001
Query: 654 EHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGS 713
+E A+ E L+++L + LL ++ EA+ E I +LQ + G
Sbjct: 1002 --KEAAWRELEAERAQ-----LQSQLQREQEELLARL-EAEKEELSEEIAALQQERDEGL 1053
Query: 714 LSVEDERQM-------------DDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSL 760
L E E+Q + L G + +++K + +E + +L
Sbjct: 1054 LLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL 1113
Query: 761 HCAGGE---QKEESYILSAE----LGEKCEDIGKK---LLYLEDQLHTAIHSHDEDLIQS 810
+ Q+EE+ A+ L E+ D+GK+ L ++L T + ED
Sbjct: 1114 TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLL-EDARDG 1172
Query: 811 LRREL----QMVKETLQAMILQLQPAKE--------AGEREA 840
LRREL + ++E+ + +Q Q A E A EREA
Sbjct: 1173 LRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Score = 42.0 bits (97), Expect = 0.002
Identities = 85/388 (21%), Positives = 158/388 (40%), Gaps = 38/388 (9%)
Query: 360 LQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRG 419
LQE++V + ++ TL Q + LE+ + +L + Q +S + +++ RR
Sbjct: 1583 LQEESVRRSERERRATLDQ-VATLERSLQATESELRASQEKISKMKAN-ETKLEGDKRRL 1640
Query: 420 ATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVL 479
+ + L ++ R LE Q S + ++ R+ + Q LQ +++LQ ++
Sbjct: 1641 KEVLDASESRTVKLELQRRSLEGELQRS-RLGLSDRE---AQAQALQDRVDSLQRQVADS 1696
Query: 480 EAKDQQLR----------REIEEQEQQLQWQGCDLTPLVGQ--LSLGQLQEVSKALQDTL 527
E K L+ ++EE E L+ + LT + Q SL ++ + LQ L
Sbjct: 1697 EVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKAL 1756
Query: 528 ASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIET---- 583
+ + LQER+ + +L E + + TLR +V D+E
Sbjct: 1757 TAC---------EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVE 1807
Query: 584 ---QLPALLEAKMHAISGN--HFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
QL L E G T + L +E R L L+ L++L +
Sbjct: 1808 AEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERS 1867
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEAC 698
+++D LRR ++ E S E+T++ + K +L ++ EA +
Sbjct: 1868 ALRLEKDRVALRRTLDKVEREKLRS-HEDTVR-LSAEKGRLDRTLTGAELELAEAQRQIQ 1925
Query: 699 RLLIQSLQLQEARGSLSVEDERQMDDLE 726
+L Q + L+++ +E + Q LE
Sbjct: 1926 QLEAQVVVLEQSHSPAQLEVDAQQQQLE 1953
Score = 39.3 bits (90), Expect = 0.016
Identities = 86/387 (22%), Positives = 158/387 (40%), Gaps = 28/387 (7%)
Query: 268 LLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWD 327
L+ TR S LA + R +RD S + D + ++L L + AH+ +
Sbjct: 1078 LMGTRHS--LATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAA-AHAQE 1134
Query: 328 TLLRKWEPVLRDC-LLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQE 386
+R+ + RD R+ E LR +L +L EDA + + E ++ E E
Sbjct: 1135 --VRRLQEQARDLGKQRDSCLREAEELRTQL-RLLEDARDGLRRELLEAQRKLRESQEGR 1191
Query: 387 KISLHFQLPSRQPA--LSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTA 444
++ RQ A L LG A+ + ALRR + S R+ +L
Sbjct: 1192 EVQ-------RQEAGELRRSLGE-GAKEREALRRSNEELRSAVKKAESERISLKLANEDK 1243
Query: 445 QDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDL 504
+ L + R + +E +L+ ++ ++ + Q+LRR+++ + + G +L
Sbjct: 1244 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1303
Query: 505 TPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIR-SLQERIKSLNLSLKEITTK 563
L G+L+LG+ E ++ ++TL ++ E +R LQ + L E T+
Sbjct: 1304 AELQGRLALGERAE-KESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTR 1362
Query: 564 VCMSEKFCSTLRKKVNDIETQLPAL--LEAKMHAISGNHFWTAKDLTEEIRSLTSEREGL 621
+ +L + + QL LE K+ A A +L + + +GL
Sbjct: 1363 ---ERRLLGSLEEARGTEKQQLDHARGLELKLEAARAE----AAELGLRLSAAEGRAQGL 1415
Query: 622 EGLLSKLLVLSSRNVKKLGSVKEDYNR 648
E L+++ V +LG ++ R
Sbjct: 1416 EAELARVEVQRRAAEAQLGGLRSALRR 1442
Score = 35.4 bits (80), Expect = 0.23
Identities = 105/498 (21%), Positives = 198/498 (39%), Gaps = 97/498 (19%)
Query: 375 TLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLR 434
TL+ ++ LE + L +R A + + L A ++ + R +Q S
Sbjct: 14 TLETVIQTLESSVLCQEKGLGARDLAQDAQITSLPALIREIVTRNLSQPES--------- 64
Query: 435 MEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREI---- 490
P LL T SL L +E Q LQ+E+ ++ + A+ +L +
Sbjct: 65 --PVLLPATEMASLLS-------LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVS 115
Query: 491 EEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERI 550
E EQ L+ + +L + + Q E+ + LQ+ AS + +++ QE
Sbjct: 116 ERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRR---------KLQAYQEGQ 166
Query: 551 KSLNLSLKEITTKVCMSEKFCSTLRKKV------------------NDIETQLPALLEAK 592
+ ++ + K+ +K CS L +++ D+E+ L L E +
Sbjct: 167 QRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQ 226
Query: 593 MHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRRE 652
+ S ++ ++ E+ G ++ L S +++K V D+ R R+E
Sbjct: 227 QRSAS----------LAQVNAMLREQLDQAGSANQAL---SEDIRK---VTNDWTRCRKE 270
Query: 653 VEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLG---KVWEADLEACRLLIQ------ 703
+EH+E A+ +E+ Y ++L ++G V E + R L+Q
Sbjct: 271 LEHREAAWRRE-EESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELA 329
Query: 704 --SLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLH 761
S +QEA LS R + AA L ++ + + KVL E
Sbjct: 330 RTSRAVQEAGLGLST-GLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDL------- 381
Query: 762 CAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKET 821
+Q+ +S + A+L + ++G + LE Q + ++D + ++L E
Sbjct: 382 ---AQQQMQSDLDKADLSARVTELGLAVKRLEKQ------NLEKD---QVNKDLTEKLEA 429
Query: 822 LQAMILQLQPAKEAGERE 839
L+++ LQ Q A E + E
Sbjct: 430 LESLRLQEQAALETEDGE 447
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 347 QMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLG 406
+++ + +LQ+L+E + + + A ++ L+ E+ L +L S Q AL+
Sbjct: 1802 ELQRVEAEGQLQQLREVLRQRQEGEAAAL--NTVQKLQDERRLLQERLGSLQRALAQLEA 1859
Query: 407 HLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQ----EK 462
++ALR + A R + R E T + L R D L E
Sbjct: 1860 EKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVR--LSAEKGRLDRTLTGAELEL 1917
Query: 463 QQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQ 500
+ Q++I+ L+A++ VLE + E++ Q+QQL+ Q
Sbjct: 1918 AEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQ 1955
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 59.3 bits (142), Expect = 1e-08
Identities = 114/534 (21%), Positives = 214/534 (40%), Gaps = 85/534 (15%)
Query: 345 RRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQ----------RLEDLEQEKISLHFQL 394
++QM+ I + QK+ +A D K + + + L++L QE + +H +
Sbjct: 835 KKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEK 894
Query: 395 PSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITR 454
+ + LS L AQV+ Q + + H + R T SL +
Sbjct: 895 RTAEAELSR-LHREVAQVR--------QHMADLEGHLQSAQKERDEMETHLQSLQFDKEQ 945
Query: 455 RDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTP-------- 506
+ + + L+K+IE LQ Q+ R+ I EQ+Q+++ G DLT
Sbjct: 946 MVAVTEANEALKKQIEELQ----------QEARKAITEQKQKMRRLGSDLTSAQKEMKTK 995
Query: 507 ------LVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEI 560
VG LS +LQE A + A GQ+ ++ +L ERI++L L+ +
Sbjct: 996 HKAYENAVGILS-RRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAV 1054
Query: 561 T-TKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHF-WTAKDLTEEIRSLTSER 618
+ +K + ++ + ++E +LE + F K L E + L E
Sbjct: 1055 SHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALEL 1114
Query: 619 EGLEGLL-----SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKY-- 671
E +G L S + ++ + K + + ++ ++ Q ++ MK+
Sbjct: 1115 EHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLV 1174
Query: 672 ------METLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVED------E 719
+E K K+ S K + EA SL+L E + L ++ +
Sbjct: 1175 QALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQ 1234
Query: 720 RQMDDLEGAAPPIPPRLHSED---------KRKTPLKVLEEWKTHLIPSLHCAGGEQKEE 770
+ DDL+ I HS++ + + L++L++ + S G ++ E
Sbjct: 1235 AEADDLQ-----IREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQL-SKQPVGNQEMEN 1288
Query: 771 SYILSAELGEKCEDIG--KKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETL 822
L E+ +K +I K+ L L +Q + L+Q+++ EL+M +E L
Sbjct: 1289 ---LKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDL 1339
Score = 39.7 bits (91), Expect = 0.012
Identities = 96/463 (20%), Positives = 187/463 (40%), Gaps = 56/463 (12%)
Query: 380 LEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRL 439
LE L+ E +SL QL Q G +AAQ+Q Q+A+ ++ +
Sbjct: 610 LEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAA----FMQIQEAKTM 665
Query: 440 LEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQW 499
+E Q R + E+++LQ+ ++ + LE + +Q++ + +++QQL+
Sbjct: 666 VEEDLQ-------RRLEEFEGERERLQRMADSAAS----LEQQLEQVKLTLLQRDQQLEA 714
Query: 500 QGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKE 559
+ L+ QL+L Q +ALQ +++ +LQ L L E
Sbjct: 715 LQQEHLDLMKQLTLTQ-----EALQSR-------------EQSLDALQTHYDELQARLGE 756
Query: 560 ITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWT--AKDLTEEIRSLTSE 617
+ + E L+ + +E L A K G ++ +E + L E
Sbjct: 757 LQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREE 816
Query: 618 REGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKN 677
G + L ++ K++ +KE + L+++V + + + K+ + ++ +
Sbjct: 817 LAIKSGQVEHLQQETAALKKQMQKIKEQF--LQQKVMVEAYRRDATSKDQLISELKATRK 874
Query: 678 KLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQ-MDDLEGAAPPIPPRL 736
+L S L ++ + E ++ + + +R V RQ M DLEG +
Sbjct: 875 RLDSELKELRQELMQVHGEK-----RTAEAELSRLHREVAQVRQHMADLEG---HLQSAQ 926
Query: 737 HSEDKRKTPLKVLEEWKTHLI------PSLHCAGGEQKEESYILSAELGEKCEDIGKKLL 790
D+ +T L+ L+ K ++ +L E ++E+ E +K +G L
Sbjct: 927 KERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLT 986
Query: 791 YLEDQLHTAIHSHDEDLIQSLRRELQ---MVKETLQAMILQLQ 830
+ ++ T H E+ + L R LQ KE A + QL+
Sbjct: 987 SAQKEMKTK-HKAYENAVGILSRRLQEALAAKEAADAELGQLR 1028
Score = 39.3 bits (90), Expect = 0.016
Identities = 113/510 (22%), Positives = 205/510 (40%), Gaps = 89/510 (17%)
Query: 373 AETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTP 432
AET ++ L+ L+ EK+ L QL + L+ + AL+ A QA T
Sbjct: 401 AETQEEMLQVLK-EKMRLEGQLEA-----------LSLEASQALKEKAELQAQLAALSTK 448
Query: 433 LRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEE 492
L+ + + H S R+D L E++ L+ + LE L+ +E
Sbjct: 449 LQAQV--------ECSHSSQQRQD-------SLSSEVDTLKQSCWDLERAMTDLQNMLEA 493
Query: 493 QEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLAS--AGQIPFHAEPPETIRSLQERI 550
+ L DL Q++ Q Q + ++D S + H + + + +LQ ++
Sbjct: 494 KNASLASSNNDL-----QVAEEQYQRLMAKVEDMQRSMLSKDNTVH-DLRQQMTALQSQL 547
Query: 551 KSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEE 610
+ + L +T+K+ S+ S+L+ + QL EA++ +T+
Sbjct: 548 QQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQA 607
Query: 611 --IRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY------ET 662
+ L E L +L R++K+ G + + ++ QE A+ +T
Sbjct: 608 GLLEHLKLENVSLS---QQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKT 664
Query: 663 SVKENTMKYME-----------------TLKNKLCSCKCPLLGKVWEADLEACR-----L 700
V+E+ + +E +L+ +L K LL + + LEA + L
Sbjct: 665 MVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQR--DQQLEALQQEHLDL 722
Query: 701 LIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRL----HSEDKRKTPLKVLEEWKTHL 756
+ Q QEA S E+ +D L+ + RL R+ + +L+ K L
Sbjct: 723 MKQLTLTQEALQS----REQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIIL 778
Query: 757 IPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQ----SLR 812
+L A KEE + L E E+ + L L ++L AI S + +Q +L+
Sbjct: 779 EAALQ-AAKSGKEELDRGARRLEEGTEETSETLEKLREEL--AIKSGQVEHLQQETAALK 835
Query: 813 RELQMVKETLQAMILQLQPAKEAGEREAAA 842
+++Q +KE LQ + EA R+A +
Sbjct: 836 KQMQKIKE----QFLQQKVMVEAYRRDATS 861
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/218 (23%), Positives = 90/218 (41%), Gaps = 37/218 (16%)
Query: 330 LRKWEPVLRDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDK--AETLQQRLEDLEQEK 387
LR+ +L L + R+ +++ L L++Q + + E D K + LQ LE +++
Sbjct: 1131 LREHNSILETALAK--READLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKV 1188
Query: 388 ISLHFQLPSRQ----------PALSSFLGHLAAQVQAALRRGATQQASGDDTH------- 430
SL Q+ + + A S L + ++QA QA DD
Sbjct: 1189 NSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHS 1248
Query: 431 ----------TPLRMEPRLLEPTAQDSLH---VSITRRDWLLQEKQQLQKEIEALQARMF 477
R + +LL+ + L V + L E Q ++EI++L+ +
Sbjct: 1249 QEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQ-- 1306
Query: 478 VLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQ 515
L+ +QQ R+E+E +Q LQ +L LS+ Q
Sbjct: 1307 -LDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQ 1343
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 58.9 bits (141), Expect = 2e-08
Identities = 117/506 (23%), Positives = 208/506 (41%), Gaps = 72/506 (14%)
Query: 337 LRDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPS 396
L LL RQ+ RLK Q+ D + LQ +L LE++
Sbjct: 419 LHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQL--------K 470
Query: 397 RQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQD--SLHVSITR 454
+ S+ L H Q+ ++ QQA T LR LE + I
Sbjct: 471 EKVTNSTELQH---QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQN 527
Query: 455 RDWLLQEKQQ----LQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQ 510
+ LLQ+ ++ L+KE E L A++ E + L +++E+ LQ Q LT
Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAGEGETAVL-NQLQEKNHTLQEQVTQLTE---- 582
Query: 511 LSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKF 570
L E K Q+ L Q E +R+ Q+R+ SL S+ E+ +++ S
Sbjct: 583 -KLKNQSESHKQAQENLHDQVQ-----EQKAHLRAAQDRVLSLETSVNELNSQLNES--- 633
Query: 571 CSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLV 630
++KV+ ++ Q+ A E + A + A DL + + + + + L+K+
Sbjct: 634 ----KEKVSQLDIQIKAKTELLLSAEAAKTAQRA-DLQNHLDTAQNALQDKQQELNKITT 688
Query: 631 LSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKV 690
+ KL +E ++L ++ + Y S+++ T E L+ ++ K
Sbjct: 689 QLDQVTAKLQDKQEHCSQLESHLKEYKEKY-LSLEQKT----EELEGQI---------KK 734
Query: 691 WEAD-LEACRLLIQSLQLQEARGSLSVEDERQMD-DLEGAAPPIPPRLHSEDKRKTPLKV 748
EAD LE Q+LQ ++ +RQ++ DLE A + +L E + + ++
Sbjct: 735 LEADSLEVKASKEQALQ--------DLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRL 786
Query: 749 LEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLI 808
+ K+ + S+ +Q+EE IL + + L E ++ H + I
Sbjct: 787 DLQKKSEALESIKQKLTKQEEEKQILKQDF---------ETLSQETKIQ---HEELNNRI 834
Query: 809 QSLRRELQMVKETLQAMILQLQPAKE 834
Q+ ELQ VK +A++ +L K+
Sbjct: 835 QTTVTELQKVKMEKEALMTELSTVKD 860
Score = 51.2 bits (121), Expect = 4e-06
Identities = 110/506 (21%), Positives = 211/506 (41%), Gaps = 45/506 (8%)
Query: 361 QEDAVENDDYD-KAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRG 419
QE +++++ + + +T L+ ++ EK +L +L + + LS L +
Sbjct: 821 QETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN 880
Query: 420 ATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQ---QLQKEIEALQARM 476
+A+ D + L+ +++L + L +EK+ QL+ E+ ++Q ++
Sbjct: 881 QKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQL 940
Query: 477 FVL-------EAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQ--EVSKALQDTL 527
E ++QQL+ I E +Q + + + L G+L + LQ E+ LQ L
Sbjct: 941 IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQL 1000
Query: 528 ASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPA 587
A Q A E I LQ + + K++ + E R+ + +E +L
Sbjct: 1001 TQAAQ--ELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSL 1058
Query: 588 LLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYN 647
E + + N L +E+++ + E + K L R K L ++++ +
Sbjct: 1059 AQEDLIS--NRNQIGNQNKLIQELKTAKATLE--QDSAKKEQQLQER-CKALQDIQKEKS 1113
Query: 648 RLRREV--EHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSL 705
+E+ E + A +K K + L +L S K + ++ L+ Q L
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL 1173
Query: 706 QLQEARGSL--SVEDE------------RQMDDLEGAAPPIPPRLHSEDKRK-TPLKVLE 750
+LQ SL +VE E ++ ++L+ +LHSE K K +K E
Sbjct: 1174 ELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHE 1233
Query: 751 EWKTHL---IPSLHCAGGEQKEE---SYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHD 804
E + L I +L+ G K+E S +EL ++ +D+ ++ LE +
Sbjct: 1234 ENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERR 1293
Query: 805 EDLIQSLRRELQMVKETLQAMILQLQ 830
L + L+ E ++ E LQ +L+LQ
Sbjct: 1294 ALLERCLKGEGEI--EKLQTKVLELQ 1317
Score = 45.1 bits (105), Expect = 3e-04
Identities = 98/510 (19%), Positives = 201/510 (39%), Gaps = 90/510 (17%)
Query: 355 LKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQV-- 412
L+ Q+ + D + D + ++L+Q+LE+ + E +F + + LA ++
Sbjct: 119 LQQQEAKPDGLVTDSSAELQSLEQQLEEAQTE----NFNIKQMKDLFEQKAAQLATEIAD 174
Query: 413 -------QAALRRGATQQASGDDTHTPLRMEPRL-LEPTAQDSLHVSITRRDWLLQEKQQ 464
+ +LR A Q+ + R+ L E T L + +R +++
Sbjct: 175 IKSKYDEERSLREAAEQKVT--------RLTEELNKEATVIQDLKTELLQRPG-IEDVAV 225
Query: 465 LQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQ 524
L+KE+ +Q M + + ++ +++++ ++LQ Q + QL E++K Q
Sbjct: 226 LKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLR----SELAKGPQ 281
Query: 525 DTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQ 584
+ A + ++ L+ + L + +T + E+ + L +K N+ E+
Sbjct: 282 EV----------AVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNE-ESV 330
Query: 585 LPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKE 644
++A +H KDL + + L S E L ++ V S + +KE
Sbjct: 331 SKKNIQATLH---------QKDL--DCQQLQSRLSASETSLHRIHVELSEKGEATQKLKE 379
Query: 645 DYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQS 704
+ + + + +H + ++ ++ K L+ + E + +LL
Sbjct: 380 ELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQS------------EINQLHSKLLETE 427
Query: 705 LQLQEARGSLS----------VEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKT 754
QL EA G L ++ E+Q+ DL+ + +L + T L+
Sbjct: 428 RQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ------- 480
Query: 755 HLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRE 814
H + EQ+ +A+L E D+ + L + D+ + IQ+L
Sbjct: 481 HQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDK---------DQKIQNLEAL 531
Query: 815 LQMVKETLQAMILQ---LQPAKEAGEREAA 841
LQ KE + + + L +AGE E A
Sbjct: 532 LQKSKENISLLEKEREDLYAKIQAGEGETA 561
Score = 40.8 bits (94), Expect = 0.005
Identities = 102/472 (21%), Positives = 193/472 (40%), Gaps = 51/472 (10%)
Query: 356 KLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISL---HFQLPSRQPALSSFLGHLAAQV 412
+LQKL+ N+ K +TL + L EQ+ L H + + + + L
Sbjct: 289 ELQKLKSSV--NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDC 346
Query: 413 QAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEAL 472
Q R + + S H L + + ++ V T+ L E +QLQ++ E
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVE-TKYQHLKAEFKQLQQQREEK 405
Query: 473 QARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQ 532
+ L+++ QL ++ E E+QL G+ + G+L+E + + L
Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQL-----------GE-AHGRLKEQRQLSSEKL----- 448
Query: 533 IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAK 592
+ + + LQ ++ L LKE KV S + L K + Q +A
Sbjct: 449 ----MDKEQQVADLQLKLSRLEEQLKE---KVTNSTELQHQLDKTKQQHQEQ-----QAL 496
Query: 593 MHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRRE 652
+ + DL + +R + + + ++ L LL S N+ L +ED L +
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGDKDQKIQN-LEALLQKSKENISLLEKERED---LYAK 552
Query: 653 VEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARG 712
++ E ET+V + TL+ ++ L + E+ +A L Q+QE +
Sbjct: 553 IQAGEG--ETAVLNQLQEKNHTLQEQVTQLTEKLKNQS-ESHKQAQENLHD--QVQEQKA 607
Query: 713 SLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKE--E 770
L +R + LE + + +L+ ++ + L + + KT L+ S A Q+ +
Sbjct: 608 HLRAAQDRVL-SLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQ 666
Query: 771 SYILSAE--LGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKE 820
+++ +A+ L +K +++ K L DQ+ + E Q L L+ KE
Sbjct: 667 NHLDTAQNALQDKQQELNKITTQL-DQVTAKLQDKQEHCSQ-LESHLKEYKE 716
Score = 30.8 bits (68), Expect = 5.6
Identities = 86/422 (20%), Positives = 166/422 (39%), Gaps = 57/422 (13%)
Query: 465 LQKEIEALQARMFVLEAKDQQLRREIEE----QEQQLQWQG------CDLTPLVGQLSLG 514
L++E++ LQA + + ++L++E+E+ Q+Q+ + G +L L QL
Sbjct: 88 LRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEA 147
Query: 515 QLQEVS-KALQDTLAS-----AGQIPFHAEPPETIRSLQERIKSLNLSLKEITTK---VC 565
Q + + K ++D A +I + RSL+E + L E K V
Sbjct: 148 QTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVI 207
Query: 566 MSEKFCSTLRKKVNDIETQLPALLEAK--MHAISGNHFWTAKDLTEEIRSLTSEREGLEG 623
K R + D+ L++ + M ++ ++ L +E + L S+ E
Sbjct: 208 QDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEA 267
Query: 624 LLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMK------YMETLKN 677
+S+L ++ +++ ++ +L+ V ++ T ++ EN +K +E N
Sbjct: 268 TISQLRSELAKGPQEVAVYVQELQKLKSSV-NELTQKNQTLTENLLKKEQDYTKLEEKHN 326
Query: 678 KLCSCKCPLLGKVWEADLEA----CRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIP 733
+ K + + + DL+ RL L LS + E E +
Sbjct: 327 EESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET 386
Query: 734 PRLHSEDKRKTPLKVLEEWKTH------LIPSLHC-----------AGGEQKEESYILSA 776
H + + K + EE + H I LH A G KE+ + S
Sbjct: 387 KYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSE 446
Query: 777 ELGEK---CEDIGKKLLYLEDQLHTAIHS-----HDEDLIQSLRRELQMVKETLQAMILQ 828
+L +K D+ KL LE+QL + + H D + +E Q ++++ A + +
Sbjct: 447 KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLRE 506
Query: 829 LQ 830
Q
Sbjct: 507 AQ 508
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 57.0 bits (136), Expect = 7e-08
Identities = 105/407 (25%), Positives = 165/407 (40%), Gaps = 68/407 (16%)
Query: 462 KQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSK 521
K++ QK + L AK + R+E+EE+ L + DL QL Q+Q S+
Sbjct: 854 KEEFQKTKDEL--------AKSEAKRKELEEKLVTLVQEKNDL-----QL---QVQAESE 897
Query: 522 ALQDTLASAGQI---PFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKV 578
L D Q+ F E I+ + ER + E+T K E CS L+K +
Sbjct: 898 NLLDAEERCDQLIKAKFQLEAK--IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEE-------IRSLTSEREGLEGLLSKLLVL 631
+D+E L A +E + HA K+LTEE I LT E++ L+ + L
Sbjct: 956 DDLELTL-AKVEKEKHATENK----VKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
Query: 632 SSRNVKKLGSVKEDYNRLRREVEHQETAYETSVK------------ENTMKYMETLKNKL 679
K+ S+ + ++L ++VE E++ E K E +K + L
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 680 CSCKCPLLGKVWEADLEACRLLIQ-------SLQLQEARGSLSVEDERQMDDLEGAAPPI 732
+ K L ++ + D E C+L + LQ Q+ L E +++E
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER--- 1127
Query: 733 PPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYL 792
R +E +R + LEE L L AGG + EL +K E + L L
Sbjct: 1128 ATRAKTEKQRSDYARELEE----LSERLEEAGGVTSTQ-----IELNKKRE---AEFLKL 1175
Query: 793 EDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGERE 839
L A H E ++ +LR++ L I LQ K+ E+E
Sbjct: 1176 RRDLEEATLQH-EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1221
Score = 53.5 bits (127), Expect = 8e-07
Identities = 104/525 (19%), Positives = 213/525 (40%), Gaps = 72/525 (13%)
Query: 339 DCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQ 398
D L++ + Q+E K++++ E A + ++ + T ++R LE E L + +
Sbjct: 907 DQLIKAKFQLEA-----KIKEVTERAEDEEEINAELTAKKR--KLEDECSELKKDIDDLE 959
Query: 399 PALSSFLGHLAAQVQAALRRGATQQASG-DDTHTPLRMEPRLLEPTAQ---DSLHVSITR 454
L+ A + T++ SG D+T L E + L+ Q D L +
Sbjct: 960 LTLAKVEKEKHATENKV--KNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 455 RDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLG 514
+ L + K +L++++E L++ + ++++LR ++E +++L+ DL + Q S+
Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSL----EQEKKLRVDLERNKRKLEG---DLK--LAQESIL 1068
Query: 515 QLQEVSKALQDTLASAG----QIPFHAEPPETIR-SLQERIKSLNLSLKEITTKVCMSEK 569
L+ + L + L Q+ E +T+ Q++IK L ++E+ ++
Sbjct: 1069 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 1128
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHA--ISGNHFWTAKDLTEEIRSLTSEREGL----EG 623
+ K+ +D +L L E A ++ K E L + E E
Sbjct: 1129 TRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEA 1188
Query: 624 LLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSV-------------KENTMK 670
+++ L + +V +LG ++ R+++++E +++ ++ + K N K
Sbjct: 1189 MVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEK 1248
Query: 671 YMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEG--- 727
TL+++L + GK E L Q +LQ G LS RQ+++ E
Sbjct: 1249 ICRTLEDQLSEAR----GKNEEIQRSLSELTTQKSRLQTEAGELS----RQLEEKESIVS 1300
Query: 728 -----------AAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSA 776
+ +L E+K K L + H L EQ EE A
Sbjct: 1301 QLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLR----EQYEEEQEGKA 1356
Query: 777 ELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKET 821
EL ++ + T E+L ++ ++ Q ++++
Sbjct: 1357 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDS 1401
Score = 34.7 bits (78), Expect = 0.39
Identities = 77/394 (19%), Positives = 158/394 (40%), Gaps = 49/394 (12%)
Query: 458 LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQ 517
L Q Q ++++EA+ A+ LE Q+L+ E+E+ ++ L L Q +
Sbjct: 1394 LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE----RANSLAAALDKKQ-R 1448
Query: 518 EVSKALQD--TLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLR 575
K L + T Q A E+ RSL + L + +E ++ T++
Sbjct: 1449 NFDKVLAEWKTKCEESQAELEASLKES-RSLSTELFKLKNAYEEALDQL-------ETVK 1500
Query: 576 KKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRN 635
++ ++E ++ L E A +G T +L + + + E+ ++ L +
Sbjct: 1501 RENKNLEQEIADLTE--QIAENGK---TIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
Query: 636 VKKLGSVKEDYNRLRREVEHQETAYETSV---KENTMKYMETLKNKL-----CSCKCPLL 687
K+ ++ + +++ E++ + + + K N + +ET+++ L + L
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 688 GKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLK 747
K E DL + + Q A E + + ++G +LH +D L+
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAA------ETLKHLRSVQGQLK--DTQLHLDD----ALR 1663
Query: 748 VLEEWKTHLIPSLHCAGGEQKE-ESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED 806
E+ K L A Q E E + E E+ + ++ L ++ +H+ +
Sbjct: 1664 GQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTS 1723
Query: 807 LIQSLRRELQMVKETLQAMILQLQPAKEAGEREA 840
LI + K+ L+ ++QLQ E R+A
Sbjct: 1724 LIHT--------KKKLETDLMQLQSEVEDASRDA 1749
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 55.5 bits (132), Expect = 2e-07
Identities = 121/518 (23%), Positives = 212/518 (40%), Gaps = 76/518 (14%)
Query: 352 SLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSF--LGHLA 409
S RL Q++QE E +Y++ + ++LE+EK SL L ++ L +
Sbjct: 1025 SQRLVEQEVQEKLRETQEYNRIQ------KELEREKASLTLSLMEKEQRLLVLQEADSIR 1078
Query: 410 AQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEI 469
Q +ALR+ Q+A G+ +ME LL ++ D+L QE Q L+ E+
Sbjct: 1079 QQELSALRQDM-QEAQGEQKELSAQME--LLRQEVKEK------EADFLAQEAQLLE-EL 1128
Query: 470 EA-------LQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKA 522
EA L+A ++ EAK QL+ + E QL+ + P + QL + A
Sbjct: 1129 EASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSA 1188
Query: 523 LQDTLAS-------------AGQIPFHAEPPET-IRSLQER--------IKSLNLSLKEI 560
LQ L S + + EP + RSL +R +++ +L ++
Sbjct: 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1248
Query: 561 TTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREG 620
+ +++ LR +V +E +L A +DL ++ E+
Sbjct: 1249 HQDLWKTQQTRDVLRDQVQKLEERL-----TDTEAEKSQVHTELQDLQRQLSQNQEEKSK 1303
Query: 621 LEGLLSKLLVLSSRNVKKLGSVKEDYNRLRR-EVEHQETAYETSVKENTMKYMETLKNKL 679
EG K L S ++ ++ +RLRR E++ E E + ++ K L
Sbjct: 1304 WEG---KQNSLESELMELHETMASLQSRLRRAELQRMEAQGEREL-------LQAAKENL 1353
Query: 680 CSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSE 739
+ L V EA +A I L+ AR +L +++E + E A L +
Sbjct: 1354 TAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERA-----QALQEQ 1408
Query: 740 DKRKTPL-KVLEEWKTHLIPSLHCAGGEQKEESYILSAELG--EKCEDIGKKLLYLEDQL 796
+ K K L+E L +L E++EE L ++ EK ++ K L L L
Sbjct: 1409 GELKVAQGKALQENLALLTQTL----AEREEEVETLRGQIQELEKQREMQKAALELL-SL 1463
Query: 797 HTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
+ + DL Q +EL+ + L+ + + +Q ++
Sbjct: 1464 DLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQ 1501
Score = 50.4 bits (119), Expect = 7e-06
Identities = 119/552 (21%), Positives = 221/552 (40%), Gaps = 114/552 (20%)
Query: 348 MEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPS---RQPALSSF 404
++ + L +L +L+E+ +++ R+E EQ + +L L R+ AL
Sbjct: 610 LDKVGLNQQLLQLEEEN---------QSVCSRMEAAEQARNALQVDLAEAEKRREALWEK 660
Query: 405 LGHLAAQVQAALRRGATQQAS-GDDTHTPLRMEPRLLE--------PTAQDSLHVSITRR 455
HL AQ+Q A GA QA D ++ +L E T + LH R+
Sbjct: 661 NTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQ 720
Query: 456 DWLL----QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
+ +L QEK+ L +E AL+ R+ +E Q L ++ QG + +
Sbjct: 721 EEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL---------QGLSSAKELLES 771
Query: 512 SLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLK-EITTKVCMSEKF 570
SL + Q+ + ++ T GQ+ +T+ +E I+ LK E+ T+ +E+
Sbjct: 772 SLFEAQQQNSVIEVT---KGQLEVQI---QTVTQAKEVIQGEVRCLKLELDTERSQAEQE 825
Query: 571 CSTLRKKVNDIETQLPALLEAK--MHAISGNHF---------WTAKDLTEEIRSLTSERE 619
+++ E + LE + H N W ++L + + SL E+
Sbjct: 826 RDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM 885
Query: 620 GLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKL 679
LE +L + + ++ + E + T E+++ +ET K ++
Sbjct: 886 ELE--------------MRLKEQQTEMEAIQAQREEERTQAESAL---CQMQLETEKERV 928
Query: 680 CSCKCPLLGKVWEAD----LEACR--LLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIP 733
+ L + AD LE R + +Q L+ QE G L + + +L+ AA
Sbjct: 929 SLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAA---- 984
Query: 734 PRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLE 793
R H +D L L+E + L+ +L ++ ED+ +L+ +
Sbjct: 985 -RQHRDD-----LAALQEESSSLLQD---------------KMDLQKQVEDLKSQLVAQD 1023
Query: 794 DQLHTAIHSHDEDLIQS-----LRRELQMVKETL-------QAMILQLQPAKEAGEREAA 841
D E L ++ +++EL+ K +L + +L LQ A ++E +
Sbjct: 1024 DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELS 1083
Query: 842 ASCMTAGVHEAQ 853
A + + EAQ
Sbjct: 1084 A--LRQDMQEAQ 1093
Score = 43.5 bits (101), Expect = 8e-04
Identities = 41/161 (25%), Positives = 80/161 (49%), Gaps = 8/161 (4%)
Query: 345 RRQMEVISLRLKLQKLQEDAVE---NDDYDKAET-LQQRLEDLEQEKISLHFQLPSRQPA 400
R +ME + +RLK Q+ + +A++ ++ +AE+ L Q + E+E++SL L Q
Sbjct: 882 REKME-LEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKE 940
Query: 401 LSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQ---DSLHVSITRRDW 457
L+ L Q + +Q + T L+ R L+ A+ D L
Sbjct: 941 LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSS 1000
Query: 458 LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ 498
LLQ+K LQK++E L++++ + + + +E++E+ ++ Q
Sbjct: 1001 LLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQ 1041
Score = 40.8 bits (94), Expect = 0.005
Identities = 76/365 (20%), Positives = 149/365 (40%), Gaps = 56/365 (15%)
Query: 338 RDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSR 397
++ L+R + +EV +LQ AVE D D AE LQ E + SL F+ +
Sbjct: 731 KEALVREKAALEV--------RLQ--AVERDRQDLAEQLQGLSSAKELLESSL-FEAQQQ 779
Query: 398 QPALSSFLGHLAAQVQAALRRGATQQASGD--------DTHTPLRMEPR----------- 438
+ G L Q+Q + A + G+ DT + R
Sbjct: 780 NSVIEVTKGQLEVQIQTVTQ--AKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Query: 439 ------LLEPTAQDSLHVSITRRDWLLQE---KQQLQKEIEALQARMFVLEAKDQQLRRE 489
L + A V+ R W + +Q+L K +E+L+ LE + ++ + E
Sbjct: 838 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTE 897
Query: 490 IEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQER 549
+E + Q + + + Q+ L +E L+ L + ++ A+ + + L++
Sbjct: 898 MEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKEL---ADASQQLERLRQD 954
Query: 550 IKSLNLSLKEITTKVCMS--EKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDL 607
+K L +E TT + + ++ L++ L AL E S + DL
Sbjct: 955 MKVQKLKEQE-TTGILQTQLQEAQRELKEAARQHRDDLAALQEE-----SSSLLQDKMDL 1008
Query: 608 TEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKEN 667
+++ L S+ + S+ LV + V++ ++YNR+++E+E ++ + S+ E
Sbjct: 1009 QKQVEDLKSQLVAQDD--SQRLV--EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEK 1064
Query: 668 TMKYM 672
+ +
Sbjct: 1065 EQRLL 1069
Score = 40.8 bits (94), Expect = 0.005
Identities = 105/494 (21%), Positives = 203/494 (41%), Gaps = 96/494 (19%)
Query: 376 LQQRLEDLEQEKISLHFQLPSRQPALSSF---LGHLAAQVQAALRRGATQQASGDDTHTP 432
LQ+ + LEQ+ LH ++ LS + L Q+Q A +G ++ S
Sbjct: 1748 LQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQS------- 1800
Query: 433 LRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEE 492
++ +L E AQ +L + L QE+QQ Q + E ++ + L+ +Q ++E
Sbjct: 1801 --LQSQLDE--AQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1856
Query: 493 QEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKS 552
+ +LQ +E ++ L++ LA G+ +++L+E +
Sbjct: 1857 RHGELQ----------------DHKEQARRLEEELAVEGR---------RVQALEEVLGD 1891
Query: 553 LNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIR 612
L +E + ++ C+ ++ + E + AL ++ + A + K+ +E+
Sbjct: 1892 LRAESREQEKALLALQQQCA---EQAQEHEVETRALQDSWLQAQA-----VLKERDQELE 1943
Query: 613 SLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYM 672
+L +E + SSR+ +E+ R R E + + + K
Sbjct: 1944 ALRAESQ------------SSRH-------QEEAARARAEALQEALGKAHAALQG--KEQ 1982
Query: 673 ETLKNKLCSCKCPLLGKVWEADLEAC----RLLIQSLQLQEARGSLSVEDERQMDDLEGA 728
L+ S +A L+AC R L ++L++QE G + +D R +D++
Sbjct: 1983 HLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQE--GEIQDQDLRYQEDVQQL 2040
Query: 729 APPIPPR---LHSEDKRKTPLK--VLEEWKTHLIPSLHCAGGEQKEESY--------ILS 775
+ R L + +R+ L+ + + + ++I G E++EE L
Sbjct: 2041 QQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQ 2100
Query: 776 AELGEKCEDIGK-KLLYLEDQLHTAIHSH------DEDL-IQSLRRELQMVKETLQAMIL 827
L +K ++I + + + L HSH ++ L + SL LQ E LQA +
Sbjct: 2101 LTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALR 2160
Query: 828 QLQPAKEAGEREAA 841
Q + A+E RE A
Sbjct: 2161 QTE-AREIEWREKA 2173
Score = 40.0 bits (92), Expect = 0.009
Identities = 119/552 (21%), Positives = 223/552 (40%), Gaps = 94/552 (17%)
Query: 346 RQMEVISLRLKLQKL------QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQP 399
R+ EV +LR ++Q+L Q+ A+E D + Q+ DL+QE+I
Sbjct: 1433 REEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQE--VDLQQEQIQ-------ELE 1483
Query: 400 ALSSFLGHLAAQVQA-----ALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITR 454
S L HL VQ ++R ++ D +E +LLE +D + S +
Sbjct: 1484 KCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIES--Q 1541
Query: 455 RDWLLQEKQQL--------------------QKEIEALQARMFVLEAKDQQLRREIEEQE 494
R + K+QL QK I+ L+ + L ++EE+
Sbjct: 1542 RGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERS 1601
Query: 495 QQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLN 554
Q+LQ Q + L ++ +++ LQ E + ++S +E+I+ L
Sbjct: 1602 QELQAQSSQIHDLESHSTV-----LARELQ-------------ERDQEVKSQREQIEELQ 1643
Query: 555 LSLKEITTKVCMSEKFCSTLRKKVNDIE---TQLPALLEAKMHAISGNHFWTAKDLTEEI 611
+ +T + ++ ++++ +E T+ +LE + I L E
Sbjct: 1644 RQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIK-------LSLRERG 1696
Query: 612 RSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVE-HQETAYE-TSVKENTM 669
R LT++R+ ++ + S L +K +EVE QE +E +K+
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 670 KYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEAR--GSLSVED-ERQMDDLE 726
+ ++ L K+ L + E +++ QLQEAR G L + + Q+D+ +
Sbjct: 1757 QQLQGLHRKVGETSLLLSQREQE-------IVVLQQQLQEAREQGELKEQSLQSQLDEAQ 1809
Query: 727 GAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIG 786
A L + + + + EE +L A E++++ E + +D
Sbjct: 1810 RALAQRDQELEALQQEQQQAQGQEERVKEKADALQGA----LEQAHMTLKERHGELQDHK 1865
Query: 787 KKLLYLEDQLHTAIHSHD----EDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAAA 842
++ LE++L A+ E+++ LR E + ++ L A LQ Q A++A E E
Sbjct: 1866 EQARRLEEEL--AVEGRRVQALEEVLGDLRAESREQEKALLA--LQQQCAEQAQEHEVET 1921
Query: 843 SCMTAGVHEAQA 854
+ +AQA
Sbjct: 1922 RALQDSWLQAQA 1933
Score = 39.7 bits (91), Expect = 0.012
Identities = 84/413 (20%), Positives = 169/413 (40%), Gaps = 45/413 (10%)
Query: 455 RDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQ---LQWQGCDLTPLVGQL 511
RD L + LQ E+++L +L+ ++LR+++E EQ+ L+ +L L G
Sbjct: 444 RDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVEL-QLQGDS 502
Query: 512 SLGQLQEVSKALQDTLASAGQIP-----FHAEPPETIR---SLQERIKSLNL-------S 556
+ GQ +E + L + ++ A+ E++ +L+E ++S +L
Sbjct: 503 AQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQE 562
Query: 557 LKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTS 616
E+T + +E+ + L N ++T++ L A A L+ +L
Sbjct: 563 QTEVTAALARAEQSIAELSSSENTLKTEVADLRAA------------AVKLSALNEALAL 610
Query: 617 EREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLK 676
++ GL L +L + ++ + ++ N L+ ++ E E ++NT ++E
Sbjct: 611 DKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNT--HLEAQL 668
Query: 677 NKLCSCKCPL---LGKVWEADLEACRLLIQSLQLQEARGS----LSVEDERQMDDLEGAA 729
K L L + E E + L +S QEA + L E +RQ + L A
Sbjct: 669 QKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 728
Query: 730 PPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLH-CAGGEQKEESYILSAELGEKCEDIGKK 788
+ + + L+ +E + L L + ++ ES + A+ ++ K
Sbjct: 729 QEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG 788
Query: 789 LLYLEDQLHTAIHSHDEDLIQSLRREL----QMVKETLQAMILQLQPAKEAGE 837
L ++ Q T + ++ L+ EL ++ A QL A++ G+
Sbjct: 789 QLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGK 841
Score = 32.0 bits (71), Expect = 2.5
Identities = 48/191 (25%), Positives = 80/191 (41%), Gaps = 43/191 (22%)
Query: 338 RDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSR 397
RD LR++++ E + + Q++QE+ ++ E ++ + L Q L L +
Sbjct: 2047 RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQK 2106
Query: 398 QPALSSFLGHLAAQVQAALRRGATQQASGDD----THTPLRMEPRLLEPTAQDSLHVSIT 453
+ Q L TQQ + + +H ME + L+ DSL
Sbjct: 2107 E--------------QEILELRETQQRNNLEALPHSHKTSPMEEQSLK---LDSL----- 2144
Query: 454 RRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSL 513
+ +LQ+E+E LQA + EA REIE +E+ Q L+ + S+
Sbjct: 2145 --------EPRLQRELERLQAALRQTEA------REIEWREKA---QDLALSLAQTKASV 2187
Query: 514 GQLQEVSKALQ 524
LQEV+ LQ
Sbjct: 2188 SSLQEVAMFLQ 2198
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 55.5 bits (132), Expect = 2e-07
Identities = 95/410 (23%), Positives = 168/410 (40%), Gaps = 62/410 (15%)
Query: 458 LLQEKQQLQKEIEALQARMFV-------LEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQ 510
LL E ++L ++ + ++ LE +L++E + ++L++ CD L+
Sbjct: 1800 LLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELL-- 1857
Query: 511 LSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKF 570
Q E S+ L L HA+ + + + +N S KE V E
Sbjct: 1858 ----QRVETSEGLNSDLE------MHADKSSR-EDIGDNVAKVNDSWKERFLDV---ENE 1903
Query: 571 CSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKD----------LTEEIRSLTSEREG 620
S +R + IE + LEA + + KD L EE+ +TSER
Sbjct: 1904 LSRIRSEKASIEHEA-LYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ 1962
Query: 621 LEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQET-------AYETSVKENTMKYME 673
L G L + S+ L + E +E+E ++ E VKE T + ++
Sbjct: 1963 LRGELDTM----SKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT-ELLQ 2017
Query: 674 TLK---NKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAP 730
TL ++L K L K+ + ++ L + +L+ L+ E E + + E
Sbjct: 2018 TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESES--- 2074
Query: 731 PIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCA--GGEQKEESYILS---AELGEKCEDI 785
+ RL D K L V + + L+ A +EE + L +L + E
Sbjct: 2075 -LQARLSESDYEK--LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Query: 786 GKKLLYLEDQLHTAIHSHD--EDLIQSLRRELQMVKETLQAMILQLQPAK 833
KK L++ ++L +D +D +++L RELQM +E + +IL + +K
Sbjct: 2132 EKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSK 2181
Score = 45.4 bits (106), Expect = 2e-04
Identities = 100/496 (20%), Positives = 203/496 (40%), Gaps = 66/496 (13%)
Query: 374 ETLQQRLEDLEQEKISLHFQLPSRQ---PALSSFLGHLAAQVQAALRRGATQQASGDDTH 430
E L+ R+E E++++ + +L R+ +L + +L ++Q + +++
Sbjct: 2122 EKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSK 2181
Query: 431 TPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREI 490
+ +E A+ SL V L EK+ L K+I+ Q ++ L+ + +
Sbjct: 2182 AEVETLKTQIEEMAR-SLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLL 2240
Query: 491 EEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKAL------QDTLASAGQIPFHAEPP-ETI 543
EE+E Q + Q + + ++ QL+E+++A+ Q+ + + Q +PP E
Sbjct: 2241 EEKE-QAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ---SLDPPIEEE 2296
Query: 544 RSLQERIKSLNLSLKEITTK-VCM------SEKFCSTLRKKVNDIETQLPALLEAKMHAI 596
L+ I+ L L+ K +C+ SE L+ +V ++E +L + HA
Sbjct: 2297 HQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAA 2356
Query: 597 --SGNHFWTAKDLTEEIRSLTSEREGLE----------GLLSKLLVLSSRNVKKLGSVKE 644
+ N + L +I +T GLE L+ L + +L +
Sbjct: 2357 LEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINS 2416
Query: 645 DYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRL---- 700
+ + +E E + + +KE + ME L+ +L + D EAC+
Sbjct: 2417 SFENILQEKEQE----KVQMKEKSSTAMEMLQTQLKELNERV--AALHNDQEACKAKEQN 2470
Query: 701 ---LIQSLQLQEARGSLSVEDERQ-----MDDLEGAAPPI---PPRLHSEDKRKTPLKVL 749
++ L+L++A+ +++ + + G + +L +D+ + LK
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2530
Query: 750 EEWKTHLIPSL------HCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSH 803
+ + L+ L H EQ E L+ EL +K + + K L+D L S+
Sbjct: 2531 IQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2590
Query: 804 DEDLIQSLRRELQMVK 819
++L EL++ K
Sbjct: 2591 -----KNLENELELTK 2601
Score = 43.5 bits (101), Expect = 8e-04
Identities = 101/493 (20%), Positives = 194/493 (39%), Gaps = 60/493 (12%)
Query: 345 RRQMEVISLRLKLQKLQEDAVEND-DYDKAET----LQQRLEDLEQEKISLHFQLPSRQP 399
+ ++E+I L K +++ V YD+A T L+Q+L+ L ++ S +
Sbjct: 324 KAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARC 383
Query: 400 ALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLL 459
+L + + Q L R + R + Q+ + + L
Sbjct: 384 SLEQKIKEKEKEFQEELSR-----------------QQRSFQTLDQECIQMKAR----LT 422
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
QE QQ + LQA + L + QQL +EE +Q+L C Q S + E+
Sbjct: 423 QELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKL----CRAEQAF-QASQIKENEL 477
Query: 520 SKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVN 579
+++++ + H+E + L LK I + S+ F ++ K
Sbjct: 478 RRSMEEMKKENNLLKSHSE------QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNT 531
Query: 580 DIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKL 639
ET L L E K++ + T + L + L +R+ + LL K + KL
Sbjct: 532 SQETMLRDLQE-KIN--QQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKL 588
Query: 640 GSVKEDYNRLRREVEHQETAYETSVKENTM-----KYMETLKNKLCSCKCPLLGKVWEAD 694
+++ L +E ++ YE +E T+ E L ++ S K L K+
Sbjct: 589 SKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKI--NH 646
Query: 695 LEAC--RLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEW 752
LE C I+S + E +L ++ E ++ + + + +K L++
Sbjct: 647 LETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQ- 705
Query: 753 KTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED-LIQSL 811
K H ++ E + +++L + ED+ KL L +++ D+D Q L
Sbjct: 706 KAEFSDQKH---QKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI------MDKDRCYQDL 756
Query: 812 RRELQMVKETLQA 824
E + +++ L++
Sbjct: 757 HAEYESLRDLLKS 769
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/370 (20%), Positives = 150/370 (40%), Gaps = 35/370 (9%)
Query: 479 LEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAE 538
L+A++Q+LR +I E E +LQ ++ V + QLQ + KA + + E
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQ-LEKAKVELI----------E 331
Query: 539 PPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISG 598
+ + ++ + + +TK E+ L+K D+ Q A+ ++
Sbjct: 332 KEKVLNKCRDELVRTTAQYDQASTKYTALEQ---KLKKLTEDLSCQRQNAESARC-SLEQ 387
Query: 599 NHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQET 658
K+ EE L+ ++ + L + + + +R ++L K +N L+ E++
Sbjct: 388 KIKEKEKEFQEE---LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL-- 442
Query: 659 AYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSL---- 714
TSVK+ +E K KLC + + ++A L +S++ + +L
Sbjct: 443 ---TSVKQQLENNLEEFKQKLCRAE-----QAFQASQIKENELRRSMEEMKKENNLLKSH 494
Query: 715 SVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYIL 774
S + R++ LE I L+ +K + ++ L +Q E+ +
Sbjct: 495 SEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ--ENSLT 552
Query: 775 SAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
+L D+ K+ +D L H H E L L + + K L A+ L+ + +E
Sbjct: 553 LEKLKLAVADLEKQRDCSQDLLKKREH-HIEQLNDKLSKTEKESKALLSALELKKKEYEE 611
Query: 835 AGEREAAASC 844
E + SC
Sbjct: 612 LKEEKTLFSC 621
Score = 38.1 bits (87), Expect = 0.035
Identities = 115/498 (23%), Positives = 193/498 (38%), Gaps = 96/498 (19%)
Query: 366 ENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQAS 425
E D K T +L + +EK +L S Q + A+V+ + Q
Sbjct: 1966 ELDTMSKKTTALDQLSEKMKEKTQ---ELESHQSECLHCIQVAEAEVK---EKTELLQTL 2019
Query: 426 GDDTHTPLRMEPRL---LEPTAQDSLHVSITRRDW------LLQEKQQLQKEIEALQARM 476
D L+ + L L+ +DS +S+T+ + L +EK+ L KE E+LQAR+
Sbjct: 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARL 2079
Query: 477 FVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFH 536
E ++L VSKAL+ L G+
Sbjct: 2080 -------------SESDYEKL--------------------NVSKALEAALVEKGEFALR 2106
Query: 537 -AEPPETIRSLQERIKSLNLSLK-------EITTKVCMSEKFCSTLRKKVNDIETQLPAL 588
+ E + L+ I+ L + ++ I K+ E+ +L+ KV ++E +L
Sbjct: 2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMS 2166
Query: 589 LEAKMHAI-----SGNHFWTAKDLTEEI-RSLTSEREGLEGLLSKLLVLSSRNVKKLGSV 642
E + I S T K EE+ RSL L L S+ L+ + +K G +
Sbjct: 2167 EENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL 2226
Query: 643 KE---DYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACR 699
E + + +E +E A E +KE + +E L+N+L + D E +
Sbjct: 2227 SELDKLLSSFKSLLEEKEQA-EIQIKEESKTAVEMLQNQLKELNEAVAALC--GDQEIMK 2283
Query: 700 LLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRK-TPLKVLEEWKTH--- 755
QSL +E+E Q L + + RL +++K++ L+ L+E + H
Sbjct: 2284 ATEQSL-------DPPIEEEHQ---LRNSIEKLRARLEADEKKQLCVLQQLKESEHHADL 2333
Query: 756 -------LIPSLHCAGGEQKEESYILSAELGE------KCEDIGKKLLYLEDQLHTAIHS 802
L L A Q+ + GE K E + + L LE + T I S
Sbjct: 2334 LKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVT-IRS 2392
Query: 803 HDEDLIQSLRRELQMVKE 820
E+L L++E + + E
Sbjct: 2393 EKENLTNELQKEQERISE 2410
Score = 35.4 bits (80), Expect = 0.23
Identities = 107/565 (18%), Positives = 214/565 (37%), Gaps = 99/565 (17%)
Query: 338 RDCL--LRNRRQMEVISLRLKLQKLQEDA--------VENDDYDKAETLQQRLEDLEQEK 387
RDC L +R+ + L KL K ++++ ++ +Y++ + + + E
Sbjct: 567 RDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN 626
Query: 388 ISLHFQLPSRQPALSSFLGHLAAQVQAAL-------RRGATQQASGDDTHTPLRMEPRLL 440
L Q+ S + L S + HL ++ R T + ++ +R +L
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 441 EPTAQDSLHVSITRRDWL-LQEK-----QQLQKEIE-------ALQARMFVLEAKDQQLR 487
+ S+ V + ++ LQ+K Q+ QKEIE L ++ LE K Q L
Sbjct: 687 D---SKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLS 743
Query: 488 REIEEQE---QQLQWQGCDLTPLVGQ---------------LSLGQLQEVSKALQDTLAS 529
EI +++ Q L + L L+ L+ Q + + + +
Sbjct: 744 NEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE 803
Query: 530 AGQIPFHA--------EPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDI 581
G +P + P+ LQ R+ SL SL+ ++ S L+K+ ++
Sbjct: 804 QGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLES-------QKQMNSDLQKQCEEL 856
Query: 582 ETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGS 641
Q+ +E + H + ++ I L + + ++++ L K+L
Sbjct: 857 -VQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQL 915
Query: 642 VKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLL 701
+ + + E+ QE + E+++K ++ L L K + + E L
Sbjct: 916 LNDKVETEQAEI--QELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT 973
Query: 702 IQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLH 761
++ L+E SL+ E + E A I D+R+ + L +
Sbjct: 974 QENGTLKEINASLNQEKMNLIQKSESFANYI-------DEREKSISELSD---------- 1016
Query: 762 CAGGEQKEESYIL---SAELGEKCEDIGKKLLYLEDQLH--TAIHSHDEDLIQSLRRELQ 816
+ K+E IL E G ED+ +K +++ + + L ++ + EL+
Sbjct: 1017 ----QYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELE 1072
Query: 817 MVKETL----QAMILQLQPAKEAGE 837
+KE Q + +L A+E +
Sbjct: 1073 QLKEAFAKEHQEFLTKLAFAEERNQ 1097
Score = 30.8 bits (68), Expect = 5.6
Identities = 26/121 (21%), Positives = 54/121 (44%), Gaps = 6/121 (4%)
Query: 469 IEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVS----KALQ 524
+++ A++ LEA + +++E E++ + +L + G L LQ++ L+
Sbjct: 1203 LDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLK 1262
Query: 525 DTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQ 584
D A + + P + + Q L SL+ K+ EK C L+ + ++ T+
Sbjct: 1263 DCEIDAEE--KYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTE 1320
Query: 585 L 585
L
Sbjct: 1321 L 1321
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 53.9 bits (128), Expect = 6e-07
Identities = 114/535 (21%), Positives = 230/535 (42%), Gaps = 56/535 (10%)
Query: 334 EPVLRDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQ 393
+P+L LR+RR E+I L+ L K +V+ND + L++++E+LE+E
Sbjct: 910 KPLLEQKELRDRRA-ELILLKDSLAK--SPSVKNDPLSSVKELEEKIENLEKE------- 959
Query: 394 LPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSIT 453
++ ++ + +A + + L + + + LR E L + +D + + +
Sbjct: 960 CKEKEEKINK-IKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAES 1018
Query: 454 RRDWLLQ-EKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLS 512
++ LL+ EKQ Q ++E +A F E + + L R++ Q + D L+ ++
Sbjct: 1019 YKNLLLEYEKQSEQLDVEKERANNF--EHRIEDLTRQLRNSTLQCETINSDNEDLLARIE 1076
Query: 513 LGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCS 572
LQ +K L+ + + + LQ+ K +KE T V E+
Sbjct: 1077 --TLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQK-----IKEHATTVNELEELQV 1129
Query: 573 TLRKKVNDIETQLPAL----LEAKMHAISGNHFWTAKDLTEEI-RSLTSEREGLEGLLSK 627
L+K+ ++ + L +A+ + + L +E+ + LT++ +E L +
Sbjct: 1130 QLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQE 1189
Query: 628 LLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETL-KNKLCSCKCPL 686
+ + +K +++E+ L+ V+ E T +K+ +K + L +K +
Sbjct: 1190 IKI----QKQKQETLQEEITSLQSSVQQYEEK-NTKIKQLLVKTKKELADSKQAETDHLI 1244
Query: 687 LGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPL 746
L + +LEA + ++ ++Q A ++ E + + L+ +A L + +R T L
Sbjct: 1245 LQASLKGELEASQQQVEVYKIQLA--EITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTAL 1302
Query: 747 K------------VLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLED 794
+ V E++++ + +H +QK +S + G K E + L L D
Sbjct: 1303 QEECRAAKAEQATVTSEFESYKV-RVHNVLKQQKNKSMSQAETEGAKQE--REHLEMLID 1359
Query: 795 QLHTAIHSHDEDL------IQSLRRELQMVKETLQAMILQLQPAKEAGEREAAAS 843
QL + +L +Q+L+ E + E M LQ +KEA RE S
Sbjct: 1360 QLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKM-LQETVSKEAELREKLCS 1413
Score = 49.7 bits (117), Expect = 1e-05
Identities = 100/491 (20%), Positives = 199/491 (40%), Gaps = 52/491 (10%)
Query: 359 KLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRR 418
++ ED+ E D + + + + L + +EK +L FQ + L + L +
Sbjct: 769 EVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEE 828
Query: 419 GATQQASGDDTHTPLRMEPRLL----EPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQA 474
+ + LR E + E D L + L E Q L ++E +
Sbjct: 829 LKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRL-ENQNLLIQVEEVSQ 887
Query: 475 RMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIP 534
E +++ + I+E E +L PL+ Q L + L+D+LA + +
Sbjct: 888 TCSKSEIHNEKEKCFIKEHE--------NLKPLLEQKELRDRRAELILLKDSLAKSPSV- 938
Query: 535 FHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMH 594
+P +++ L+E+I++L EK C +K+N I +L A+ K
Sbjct: 939 -KNDPLSSVKELEEKIENL--------------EKECKEKEEKINKI--KLVAVKAKKEL 981
Query: 595 AISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVE 654
S T K EE+ SL SE++ L + L+ + L ++ +L E E
Sbjct: 982 DSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKE 1038
Query: 655 HQETAYETSVKENTMKYMETLKNKLCSCKC------PLLGKVWEADLEACRLLIQSLQLQ 708
+E +++ T + L+N C+ LL ++ A L +Q L++Q
Sbjct: 1039 RANN-FEHRIEDLTRQ----LRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQ 1093
Query: 709 EARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQK 768
A+ + E E + E ++ ++ + L+ ++ + L +
Sbjct: 1094 RAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELV-KKDA 1152
Query: 769 EESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQ 828
+++ +++ E+ + ++L+ +Q T ++ EDL Q ++ + Q +ETLQ I
Sbjct: 1153 QQTTLMNMEIADY-----ERLMKELNQKLTNKNNKIEDLEQEIKIQKQK-QETLQEEITS 1206
Query: 829 LQPAKEAGERE 839
LQ + + E +
Sbjct: 1207 LQSSVQQYEEK 1217
Score = 33.9 bits (76), Expect = 0.66
Identities = 104/511 (20%), Positives = 200/511 (39%), Gaps = 59/511 (11%)
Query: 339 DCLLRNRRQMEVISLRLKLQKLQ-----EDAVENDDYDKAETLQQ-------RLEDLEQE 386
D LL + + E L LK + ++ ED+V D + L+Q +E+L+ E
Sbjct: 79 DALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMG-DAHKELEQSHINYVKEIENLKNE 137
Query: 387 KISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQD 446
+++ + + L L A Q L Q + +D L+ E + P ++
Sbjct: 138 LMAVRSKYSEDKANLQKQLEE-AMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEE 196
Query: 447 SLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTP 506
+ + D EK++ +++ ++EA Q ++ I +++L
Sbjct: 197 QILYLQKQLDATTDEKKETVTQLQN------IIEANSQHYQKNINSLQEELL-------- 242
Query: 507 LVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQER-IKSLNLSLKEITTKVC 565
QL +EV + + ASA + H + L+E +K S K I K
Sbjct: 243 ---QLKAIHQEEVKELMCQIEASAKE---HEAEINKLNELKENLVKQCEASEKNIQKKY- 295
Query: 566 MSEKFCSTLRKKVNDI--ETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEG 623
E LRK ++ + Q+ ++L + + K L + ++ L S+ L+
Sbjct: 296 --ECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKD 353
Query: 624 LLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCK 683
++ + L + +K+++ R ++E + + KE +E LK++L
Sbjct: 354 EVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLA-KEEQGCVIEKLKSELAG-- 410
Query: 684 CPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRK 743
L K + +E +QSL+ Q + +S +E + D E + + K
Sbjct: 411 ---LNKQFCYTVEQHNREVQSLKEQHQK-EISELNETFLSDSEKEKLTLMFEIQG---LK 463
Query: 744 TPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSH 803
+ L++ K I + +E IL ELGE I ++ ++ Q + +H
Sbjct: 464 EQCENLQQEKQEAILNYESL----REIMEILQTELGESAGKISQEFESMKQQQASDVH-- 517
Query: 804 DEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
+L Q LR K+ L + +LQ E
Sbjct: 518 --ELQQKLRTAF-TEKDALLETVNRLQGENE 545
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 53.9 bits (128), Expect = 6e-07
Identities = 93/410 (22%), Positives = 171/410 (41%), Gaps = 83/410 (20%)
Query: 459 LQEKQQLQKEIEALQARMFVLEA---KDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQ 515
L + + +KE+ +++ L+ K + R+E+EE+ L + DL Q
Sbjct: 839 LLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDL----------Q 888
Query: 516 LQEVSKALQDTLASAGQ-----IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKF 570
LQ +A QD LA A + I + ++ + ER++ E+T K E
Sbjct: 889 LQV--QAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 571 CSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLV 630
CS L++ ++D+E L A +E + HA ++++LT E GL+ +++KL
Sbjct: 947 CSELKRDIDDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDEIIAKL-- 992
Query: 631 LSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTM--KYMETLKNKLCSCKCPLLG 688
K+ +++E + + +++ +E T K + ++ L+ L K
Sbjct: 993 -----TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEK----- 1042
Query: 689 KVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKV 748
KV DLE + ++ G L + E M DLE + RL +D L
Sbjct: 1043 KV-RMDLERAK--------RKLEGDLKLTQESIM-DLENDKQQLDERLKKKDFELNALNA 1092
Query: 749 LEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHT--AIHSHDED 806
+ E+ L ++L +K +++ ++ LE++L + E
Sbjct: 1093 ------------------RIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK 1134
Query: 807 LIQSLRRELQMVKETLQ----AMILQLQPAKEAGEREAAASCMTAGVHEA 852
L L REL+ + E L+ A +Q++ K +REA M + EA
Sbjct: 1135 LRSDLSRELEEISERLEEAGGATSVQIEMNK---KREAEFQKMRRDLEEA 1181
Score = 47.0 bits (110), Expect = 8e-05
Identities = 110/523 (21%), Positives = 209/523 (39%), Gaps = 86/523 (16%)
Query: 345 RRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQE---KISLHFQLPSRQPAL 401
++ E+ +L +++ E A+ + K + LQ R+E+LE+E + + ++ + L
Sbjct: 1082 KKDFELNALNARIE--DEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 402 SSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQE 461
S L ++ +++ A + Q + R LE + R
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 462 KQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL--SLGQLQEV 519
+L ++I+ L Q++++++E+++ + + + D+T + Q+ + L+++
Sbjct: 1200 VAELGEQIDNL-----------QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248
Query: 520 SKALQDTLASAGQIPFHAEPPETIRS----------LQERIKSLNLSLKEITTKVCMSEK 569
+ L+D + ++ ET RS LQ L+ L E + +
Sbjct: 1249 CRTLEDQMNE-----HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTR 1303
Query: 570 FCSTLRKKVNDIETQLPALLEAK---MHAI-SGNHFWTAKDLTEEIRSLTSEREGLEGLL 625
T +++ D++ QL ++AK HA+ S H L E+ T + L+ +L
Sbjct: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH--DCDLLREQYEEETEAKAELQRVL 1361
Query: 626 SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCP 685
SK EV T YET + T + +E K KL
Sbjct: 1362 SK---------------------ANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQ---- 1395
Query: 686 LLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLE---GAAPPIPPRLHSEDKR 742
++ EA+ + + L++ + L E E M D+E AA + + + D
Sbjct: 1396 ---RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD-- 1450
Query: 743 KTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLE--DQLHTAI 800
K+L EWK S QK E+ LS EL + + L +LE + + +
Sbjct: 1451 ----KILAEWKQKYEESQSELESSQK-EARSLSTELFKLKNAYEESLEHLETFKRENKNL 1505
Query: 801 HSHDEDLIQSLR------RELQMVKETLQAMILQLQPAKEAGE 837
DL + L EL+ V++ L+A ++LQ A E E
Sbjct: 1506 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAE 1548
Score = 43.1 bits (100), Expect = 0.001
Identities = 76/411 (18%), Positives = 170/411 (41%), Gaps = 58/411 (14%)
Query: 458 LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQ 517
L Q Q+ ++ +EA+ A+ LE +L+ EIE+ ++ + L
Sbjct: 1393 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA---------AAAALD 1443
Query: 518 EVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKK 577
+ + LA Q + E + S Q+ +SL+ L ++ S + T +++
Sbjct: 1444 KKQRNFDKILAEWKQ--KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501
Query: 578 VNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVK 637
+++ ++ L E G+ T +L + + L +E+ L+ L +
Sbjct: 1502 NKNLQEEISDLTEQ-----LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG 1556
Query: 638 KLGSVKEDYNRLRREVEHQETAYETSV---KENTMKYMETL----------KNKLCSCKC 684
K+ + ++N+++ E+E + + + K N ++ +++L +N+ K
Sbjct: 1557 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616
Query: 685 PLLGKVWEADLE---ACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDK 741
+ G + E +++ A R+ ++ + ++ SL + + Q+DD A + + ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1676
Query: 742 RKTPLKV-LEEWKTHLIPSLHCAGGEQKEESYILS-AELGEKCEDIGKKLLYLEDQLHTA 799
R L+ LEE + A EQ E S L+ EL E E +
Sbjct: 1677 RNNLLQAELEELR---------AVVEQTERSRKLAEQELIETSERV------------QL 1715
Query: 800 IHSHDEDLIQSLRR---ELQMVKETLQAMILQLQPAKEAGEREAAASCMTA 847
+HS + LI ++ +L ++ ++ + + + A+E ++ + M A
Sbjct: 1716 LHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Score = 37.7 bits (86), Expect = 0.046
Identities = 72/353 (20%), Positives = 136/353 (38%), Gaps = 72/353 (20%)
Query: 326 WDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQ 385
W L K +P+L+ R+ E+ S++ + +L+E A+E + + E L++++ L Q
Sbjct: 829 WMKLYFKIKPLLKSA----EREKEMASMKEEFTRLKE-ALEKSEARRKE-LEEKMVSLLQ 882
Query: 386 EKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQ 445
EK L Q+ + Q
Sbjct: 883 EKNDLQLQVQAEQ----------------------------------------------- 895
Query: 446 DSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQL---RREIEEQEQQLQWQGC 502
D+L + R D L++ K QL+ +++ + R+ E + +L +R++E++ +L+
Sbjct: 896 DNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955
Query: 503 DLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITT 562
DL + ++ + +K T AG A+ + ++LQE + L+
Sbjct: 956 DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEED 1015
Query: 563 KVCMSEKFCSTLRKKVNDIETQLPAL------LEAKMHAISGNHFWT----------AKD 606
KV K L ++V+D+E L LE + G+ T +
Sbjct: 1016 KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ 1075
Query: 607 LTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETA 659
L E ++ E L + L S+ KKL ++ L E+E + TA
Sbjct: 1076 LDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTA 1128
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 53.5 bits (127), Expect = 8e-07
Identities = 88/402 (21%), Positives = 171/402 (42%), Gaps = 34/402 (8%)
Query: 338 RDCLLRNRRQMEVISLRLKLQK---LQEDAVENDDY-DKAETLQQRLEDLEQEKISLHFQ 393
RD ++ + +Q+E L + L+K +QE A EN+ ++ L+ ++DL E L +
Sbjct: 2473 RDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Query: 394 LPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSIT 453
L + L+ + +Q + L Q ++ + L + + E +D
Sbjct: 2533 LIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANED------L 2586
Query: 454 RRDW--LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
RR + L +EKQ L KEIE+L+ + QL R++ +++ V +
Sbjct: 2587 RRSFNALQEEKQDLSKEIESLKVSI-------SQLTRQVTALQEEGTLGLYHAQLKVKEE 2639
Query: 512 SLGQLQEVSKALQDTLASAGQ--IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEK 569
+ +L + + Q +A + + E + + +++++K LK + +
Sbjct: 2640 EVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKK---ELKHLHHDAGIMRN 2696
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTA--KDLTEEIRSLTSEREGLEGLLSK 627
T ++V ++ L + + + N TA + + SL + R+ L +
Sbjct: 2697 ETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Query: 628 LLVLSSRNVKKLGSVKED--YNRLRREVEHQETAYE-TSVKENTMKYMETLKNKLCSCKC 684
L ++K+L +KE NR R+ ETA+ S +EN++ ++E L +L S
Sbjct: 2757 LKRKYDASLKELAQLKEQGLLNR-ERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDE 2815
Query: 685 PLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLE 726
LL + LE +QS +A SL E + ++LE
Sbjct: 2816 QLLH--LSSQLEDSYNQVQS--FSKAMASLQNERDHLWNELE 2853
Score = 44.7 bits (104), Expect = 4e-04
Identities = 93/425 (21%), Positives = 176/425 (41%), Gaps = 63/425 (14%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
QEKQ+L ++ + +A E + Q+ +E+EE +++++ Q + +L+E
Sbjct: 1641 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMR-----KFAKSKQQKILELEEE 1695
Query: 520 SKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCM-----SEKFCS-- 572
+ L+ + AG +T + E + S N S+KE +V M S+KF S
Sbjct: 1696 NDRLRAEVHPAG---------DTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM 1746
Query: 573 ----TLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEE-IRSLTSEREGLEGLLSK 627
+L ++V D++ Q+ + + + + ++TEE +S+ E E + L
Sbjct: 1747 SEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1806
Query: 628 LLVLSSRNVKKLGSVK----------EDYNRLRREVEH--QETAYETSVKENTMKYMETL 675
S +V S ++ N ++++ + A K+ ++ +TL
Sbjct: 1807 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTL 1866
Query: 676 KNKLCSCKCPLLG---------KVWEADLEACRLLIQSLQLQEAR-GSLSVEDERQMDDL 725
+N+ K LL K+ + ++ LL Q +Q + +R L E + DDL
Sbjct: 1867 ENE----KNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL 1922
Query: 726 E----GAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEK 781
E + + + + T ++ E + +L E +EE L E +
Sbjct: 1923 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKV 1982
Query: 782 CEDIGKKLLYLED----QLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGE 837
+I K+ YLE Q SH ++L + L+ + Q VK+ LQ ++ Q A E
Sbjct: 1983 ESEIRKE--YLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQ-LQKDCIRYQEKISALE 2039
Query: 838 REAAA 842
R A
Sbjct: 2040 RTVKA 2044
Score = 43.1 bits (100), Expect = 0.001
Identities = 84/401 (20%), Positives = 163/401 (40%), Gaps = 67/401 (16%)
Query: 347 QMEVISLRLKLQKLQE-DAVENDDYDKAETLQQRLEDLEQEK-ISLHFQLPSRQPALSSF 404
+ME+ ++ KLQ+ +E + +A+ Q E E+ + + QL ++ +S+
Sbjct: 143 EMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTL 202
Query: 405 LGHLA-AQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQ 463
L+ Q + A ++ ++ + +T L E LL+ Q + + ++ +LQ K
Sbjct: 203 QAQLSQTQAEQAAQQVVREKDARFETQVRLH-EDELLQLVTQADVETEMQQKLRVLQRKL 261
Query: 464 Q---------------LQKEIEALQARMFVLEAKDQQLRRE---------IEEQEQQLQW 499
+ LQ+E+ A + R +L + QQ+ E E +E ++
Sbjct: 262 EEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILL 321
Query: 500 QGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKE 559
+ +L +LS LQE L + AGQ AE +L+++ K+ ++E
Sbjct: 322 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQA--QAELESRYSALEQKHKA---EMEE 376
Query: 560 ITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSERE 619
T+ + +K L+ + ++ Q LL+ K A + I+ L + +
Sbjct: 377 KTSHILSLQKTGQELQSACDALKDQNSKLLQDKNE--------QAVQSAQTIQQLEDQLQ 428
Query: 620 GLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKL 679
+K + + NRL ++ ETA +TS + Y E +
Sbjct: 429 -----------------QKSKEISQFLNRL--PLQQHETASQTSFPD---VYNEGTQAVT 466
Query: 680 CSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
L +V E + E LL+ S++L+E L E+E+
Sbjct: 467 EENIASLQKRVVELENEKGALLLSSIELEE----LKAENEK 503
Score = 40.4 bits (93), Expect = 0.007
Identities = 87/394 (22%), Positives = 164/394 (41%), Gaps = 64/394 (16%)
Query: 458 LLQEKQQLQKEI-EALQARMFVL---EAKDQQLRREIEEQ-------EQQLQWQGCDLTP 506
L +EK+QLQK++ EAL +R +L + K++ LR E+++Q ++Q Q +
Sbjct: 1169 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1228
Query: 507 LVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCM 566
+ QL Q+Q V +++ L S Q E+ S + L + ++ T+ +
Sbjct: 1229 IGDQLRQLQIQ-VRESIDGKLPSTDQ-------QESCSSTPGLEEPLFKATEQHHTQPVL 1280
Query: 567 SEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLS 626
C D A+ G + + +++ + +E+ LE +S
Sbjct: 1281 ESNLCPDWPSHSEDAS------------ALQGG--TSVAQIKAQLKEIEAEKVELELKVS 1326
Query: 627 KLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPL 686
++ +++ ++E N+ E+E +T V + E+L+ KL S + +
Sbjct: 1327 STTSELTKKSEEVFQLQEQINKQGLEIESLKT-----VSHEAEVHAESLQQKLESSQLQI 1381
Query: 687 LGKVWEADLEACRLLIQSLQLQEARGSLSVED----ERQMDDLEGAAPPIPPR-LHSEDK 741
G LE R L L + S ED Q+ + E A I + ED
Sbjct: 1382 AG------LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL 1435
Query: 742 RKTPLKVLE-EWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKK---LLYLEDQLH 797
K LE + K H E+ ++ + E+ +K E+IG++ ++ +L
Sbjct: 1436 IKALHTQLEMQAKEH---------DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQ 1486
Query: 798 TAIHSHDEDLIQ--SLRRELQMVKETLQAMILQL 829
A+ S E L + SL+ EL + + T++ + L
Sbjct: 1487 AALISRKEALKENKSLQEELSLARGTIERLTKSL 1520
Score = 38.1 bits (87), Expect = 0.035
Identities = 85/402 (21%), Positives = 159/402 (39%), Gaps = 71/402 (17%)
Query: 455 RDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLG 514
+D + Q+ QLQ++ EALQ + K ++L+ +
Sbjct: 65 KDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAK----------------------A 102
Query: 515 QLQEVSKALQDTLASAGQI-PFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCST 573
+L ++K +++ A G + P + E + + + +++I K+ E+ ST
Sbjct: 103 KLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIST 162
Query: 574 LRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLV--L 631
L+ ++ + + PA +M F K +E S L+ LS+
Sbjct: 163 LQAQLTQAQAEQPAQSSTEM-----EEFVMMKQQLQEKEEFIST---LQAQLSQTQAEQA 214
Query: 632 SSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVW 691
+ + V++ + E RL E E + + V+ + + L+ KL + L+G+
Sbjct: 215 AQQVVREKDARFETQVRL-HEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQ 273
Query: 692 EADL---------EACRLLIQSLQLQEARGSL---SVEDERQMDDLEGAAPPIPPRLHSE 739
DL + ++L Q LQ EA + +VE ER+ + + ++ E
Sbjct: 274 VVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKI------LLEKMELE 327
Query: 740 -DKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILS-------AELGEKCEDI------ 785
+RK L+E HL+ AG Q E S AE+ EK I
Sbjct: 328 VAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT 387
Query: 786 GKKLL----YLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQ 823
G++L L+DQ + +E +QS + +Q +++ LQ
Sbjct: 388 GQELQSACDALKDQNSKLLQDKNEQAVQS-AQTIQQLEDQLQ 428
Score = 33.9 bits (76), Expect = 0.66
Identities = 84/462 (18%), Positives = 184/462 (39%), Gaps = 69/462 (14%)
Query: 267 SLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSW 326
+LL ++ +L++ + E + L + + L+ S+ G+ DA
Sbjct: 1895 NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSI----GNYCQDVTDAQIK 1950
Query: 327 DTLLRKWEPVLRDC----------LLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETL 376
+ LL L+ C L++ + ++E + L+K+Q E + A+ L
Sbjct: 1951 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKEL 2010
Query: 377 QQRLEDLEQEKISLHFQLPSRQPALSSF------LGHLAAQVQAALRRGATQQASGDDTH 430
Q+ L++ +QE L Q +S+ L + + Q L A +
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHR 2070
Query: 431 TPLRME----PRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQL 486
+ E LL+ T ++ V L+ K++LQ E+++++M + KD+ L
Sbjct: 2071 KKAQAELASFKVLLDDTQSEAARVLADN----LKLKKELQSNKESVKSQM---KQKDEDL 2123
Query: 487 RREIEEQEQQ--------------LQWQGCDLTPLVG--QLSLGQLQEVSKALQDTL-AS 529
R +E+ E++ L+ + L +G Q++L + + + LQ+ L ++
Sbjct: 2124 ERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDST 2183
Query: 530 AGQIPFHAEPPETIRSLQERI--------KSLNLSLKEITTKVCMSEKFCSTLRKKVNDI 581
Q+ + +++ ++R+ + + +++ ++ + E CS L+ ++ +
Sbjct: 2184 VTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQM 2243
Query: 582 ETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGS 641
+ L W +K T E++ + L+G +LL +L
Sbjct: 2244 SIHMEELKINISRLEHDKQIWESKAQT-EVQLQQKVCDTLQGENKELL-------SQLEE 2295
Query: 642 VKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCK 683
+ Y+ + E+ E+ + S+K+ + L N L CK
Sbjct: 2296 TRHLYHSSQNELAKLESELK-SLKDQ----LTDLSNSLEKCK 2332
Score = 32.7 bits (73), Expect = 1.5
Identities = 73/413 (17%), Positives = 158/413 (38%), Gaps = 41/413 (9%)
Query: 338 RDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSR 397
+DC+ R Q ++ +L ++ L+ V+ + E ++ L + + +L S
Sbjct: 2026 KDCI---RYQEKISALERTVKALE--FVQTESQKDLEITKENLAQAVEHRKKAQAELASF 2080
Query: 398 QPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR-- 455
+ L A + L+ Q++ + + ++ + LE + + + +
Sbjct: 2081 KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2140
Query: 456 -----DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQ 510
D L +EK L++ I +Q + + + QQL+ ++ QL ++ L
Sbjct: 2141 MQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD 2200
Query: 511 LS--LGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEI-------- 560
+ + ++ + D + S + E + L+++++ +++ ++E+
Sbjct: 2201 RDRVIDEAKKWERKFSDAIQSKEEEIRLKE--DNCSVLKDQLRQMSIHMEELKINISRLE 2258
Query: 561 ----------TTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEE 610
T+V + +K C TL+ + ++ +Q LE H + AK L E
Sbjct: 2259 HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQ----LEETRHLYHSSQNELAK-LESE 2313
Query: 611 IRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMK 670
++SL + L L K + + D + E ET + S +E T +
Sbjct: 2314 LKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQAS-RELTSR 2372
Query: 671 YMETLKNKLCSCKCPLLGKVWEADLEACRLLIQ-SLQLQEARGSLSVEDERQM 722
E + K L GK + L Q +++E LS E+E +
Sbjct: 2373 LHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENI 2425
Score = 30.4 bits (67), Expect = 7.3
Identities = 66/327 (20%), Positives = 120/327 (36%), Gaps = 43/327 (13%)
Query: 282 RNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCL 341
R S ++ + P P SL +++ D D LL++ + + + L
Sbjct: 2856 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDR----------DRLLKELKNLQQQYL 2905
Query: 342 LRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPAL 401
N+ E+ L+ +LQ+ Q DK + Q E+L QE +S +L +
Sbjct: 2906 QINQEITELHPLKAQLQEYQ---------DKTKAFQIMQEELRQENLSWQHELHQLRMEK 2956
Query: 402 SSFLGH---LAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEP-------TAQDSLHVS 451
SS+ H + Q A+ Q + + LR +P A S
Sbjct: 2957 SSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSAS 3016
Query: 452 ITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLR---REIEEQEQQLQWQGCDLTPLV 508
L+ E + L+ ++ + E + QQL ++ E++ L Q CD + +
Sbjct: 3017 PDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSL 3076
Query: 509 --GQLSLGQLQE----VSKALQDTLASAGQIPFHAEPPET-----IRSLQERIKSLNLSL 557
Q G L + K +Q+ A I P+ +S E ++ S
Sbjct: 3077 RENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSF 3136
Query: 558 KEITTKVCMSEKFCSTLRKKVNDIETQ 584
E ++C + + + LRK + + Q
Sbjct: 3137 SEAQQQLCNTRQEVNELRKLLEEERDQ 3163
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 53.1 bits (126), Expect = 1e-06
Identities = 86/367 (23%), Positives = 157/367 (42%), Gaps = 65/367 (17%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
+E +++E E + + EAK R+E+EE+ L + DL QL Q+Q
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAK----RKELEEKMVTLMQEKNDL-----QL---QVQAE 898
Query: 520 SKALQDTLASAGQ-IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKV 578
+ AL D Q I + I+ + ER + E+T K E CS L+K +
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
+D+E L A +E + HA ++++LT E GL+ ++KL K+
Sbjct: 959 DDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDETIAKL-------TKE 999
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEAC 698
+++E HQ+T + ++E+ + + K KL L G + E + + C
Sbjct: 1000 KKALQE---------AHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSL-EQEKKLC 1049
Query: 699 RLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIP 758
L ++ + E G L + E MD DK+ ++ E+ K
Sbjct: 1050 MDLERAKRKLE--GDLKLAQESTMDT-------------ENDKQ----QLNEKLKKKEFE 1090
Query: 759 SLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHT--AIHSHDEDLIQSLRRELQ 816
+ G + E++ L+ +L +K +++ ++ LE+++ A + E L REL+
Sbjct: 1091 MSNLQGKIEDEQA--LAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Query: 817 MVKETLQ 823
+ E L+
Sbjct: 1149 EISERLE 1155
Score = 47.4 bits (111), Expect = 6e-05
Identities = 96/516 (18%), Positives = 223/516 (43%), Gaps = 71/516 (13%)
Query: 371 DKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALR--RGATQQASGDD 428
DK TL + LEQ+ L L ++ L L +++ L+ + +T D
Sbjct: 1019 DKVNTLTKAKTKLEQQVDDLEGSL-EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDK 1077
Query: 429 THTPLRMEPRLLEPTA-------QDSLHVSITRRDWLLQEK-QQLQKEIEALQARMFVLE 480
+++ + E + + +L + + ++ LQ + ++L++EIEA +A E
Sbjct: 1078 QQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Query: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLV--GQLSLGQLQEVSKALQDTLA--SAGQIPFH 536
+ L RE+EE ++L+ G + + + + Q++ + L+++ A
Sbjct: 1138 KQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALR 1197
Query: 537 AEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAI 596
+ +++ L E+I SL +++ EK S L+ ++ND+ + + + +AK
Sbjct: 1198 KKHADSVAELGEQIDSLQRVKQKL-------EKEKSELKMEINDLASNMETVSKAK---- 1246
Query: 597 SGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLS----------SRNVKKLGSVKEDY 646
N + L +++ + ++ E + L+++L SR + + ++
Sbjct: 1247 -ANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQL 1305
Query: 647 NRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCK--CPLLGKVWEADLEACRLLIQS 704
+R ++ Q + ++E T K TL + L S + C LL + +E + EA L +
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEET-KAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRG 1364
Query: 705 L-----QLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDK------------RKTPLK 747
+ ++ + R + ++ ++LE A + RL ++ KT +
Sbjct: 1365 MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQR 1424
Query: 748 VLEEWKTHLI----PSLHCAGGEQKEESY-ILSAELGEKCEDI-------GKKLLYLEDQ 795
+ E + +I + C ++K+ ++ + AE +K E+ K+ L +
Sbjct: 1425 LQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTE 1484
Query: 796 LHTAIHSHDEDL--IQSLRRELQMVKETLQAMILQL 829
L ++++E L +++L+RE + +++ + + Q+
Sbjct: 1485 LFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQI 1520
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 51.6 bits (122), Expect = 3e-06
Identities = 92/389 (23%), Positives = 161/389 (41%), Gaps = 68/389 (17%)
Query: 462 KQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSK 521
K++ QK + L AK + R+E+EE+ L + DL QLQ S+
Sbjct: 856 KEEFQKTKDEL--------AKSEAKRKELEEKMVTLLKEKNDL----------QLQVQSE 897
Query: 522 ALQDTLASAGQ-----IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRK 576
A D+LA A + I + I+ + ER + E+T K E CS L+K
Sbjct: 898 A--DSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
Query: 577 KVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNV 636
++D+E L A +E + HA ++++LT E GL+ ++KL S+
Sbjct: 956 DIDDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDETIAKL----SKEK 999
Query: 637 KKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLG-----KVW 691
K L + HQ+T + +E+ + + K KL L G K
Sbjct: 1000 KAL------------QETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKL 1047
Query: 692 EADLE-ACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLE 750
DLE A R L L+L + D++Q+D+ L S+ + + +++
Sbjct: 1048 RMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQL 1107
Query: 751 EWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTA---------IH 801
+ K + + GE+ E A+ ++ D+ ++L + ++L A ++
Sbjct: 1108 QKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELN 1167
Query: 802 SHDEDLIQSLRRELQMVKETLQAMILQLQ 830
E Q LRR+L+ +AM+ L+
Sbjct: 1168 KKREAEFQKLRRDLEEATLQHEAMVAALR 1196
Score = 45.4 bits (106), Expect = 2e-04
Identities = 115/536 (21%), Positives = 213/536 (39%), Gaps = 70/536 (13%)
Query: 345 RRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDL--------------EQEKISL 390
+++ E+ +L K++ E AVE K + LQ R+E+L E+++ L
Sbjct: 1085 KKEFEISNLISKIE--DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDL 1142
Query: 391 HFQLPSRQPALSSFLGHLAAQVQAALRRGAT-QQASGDDTHTPLRMEPRL--LEPTAQDS 447
+L L G +AQV+ +R A Q+ D L+ E + L DS
Sbjct: 1143 SRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 448 LHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKD----------QQLRREIEEQEQQL 497
+ + D L + KQ+L+KE L+ L + +++ R +E+Q +L
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 498 QWQGCDLTPLVGQLSLGQLQ------EVSKALQDTLASAGQIPFHAE-PPETIRSLQERI 550
+ + + L+ L+ + + E S+ L + A Q+ + + I L+ ++
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
Query: 551 KSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEE 610
+ + + + S C LR++ + + L A A S W K T+
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 611 IRSLTSEREGLEGLLSKLLVLSSRNVK----KLGSVKEDYNRLRREVEHQETAYETS--- 663
I+ T E E + L++ L + +V+ K S+++ RL+ EVE E S
Sbjct: 1383 IQR-TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAA 1441
Query: 664 ------VKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLL------IQSLQLQEAR 711
+ N K + K K + L E+ + L +SL E
Sbjct: 1442 CAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETL 1501
Query: 712 GSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGE-QKEE 770
+ ++++ DL ++H +K K K +E+ K + +L A + EE
Sbjct: 1502 RRENKNLQQEISDLTEQIAEGGKQIHELEKIK---KQVEQEKCEIQAALEEAEASLEHEE 1558
Query: 771 SYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMI 826
IL +L +L ++ ++ I DE+ I L+R V ET+Q+ +
Sbjct: 1559 GKILRIQL---------ELNQVKSEVDRKIAEKDEE-IDQLKRNHTRVVETMQSTL 1604
Score = 37.7 bits (86), Expect = 0.046
Identities = 69/409 (16%), Positives = 164/409 (40%), Gaps = 54/409 (13%)
Query: 458 LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQ 517
L Q Q+ ++ +EA+ A+ LE Q+L+ E+E+ ++ + L
Sbjct: 1396 LAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA---------ACAALD 1446
Query: 518 EVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKK 577
+ + L+ Q + E + + Q+ +SL+ L ++ S TLR++
Sbjct: 1447 KKQRNFDKVLSEWKQ--KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRE 1504
Query: 578 VNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVK 637
+++ ++ L E H +L + + + E+ ++ L +
Sbjct: 1505 NKNLQQEISDLTEQIAEGGKQIH-----ELEKIKKQVEQEKCEIQAALEEAEASLEHEEG 1559
Query: 638 KLGSVKEDYNRLRREVEHQETAYETSV---KENTMKYMETL----------KNKLCSCKC 684
K+ ++ + N+++ EV+ + + + K N + +ET+ +N K
Sbjct: 1560 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK 1619
Query: 685 PLLGKVWEADLE---ACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDK 741
+ G + E +++ A RL +SL+ + E + +DD L ++
Sbjct: 1620 KMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDD----------ALRGQED 1669
Query: 742 RKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIH 801
K L ++E + +L+ + + E + E E+ I ++ L + +H
Sbjct: 1670 LKEQLAIVER-RANLL--------QAEIEELWATLEQTERSRKIAEQELLDASERVQLLH 1720
Query: 802 SHDEDLI---QSLRRELQMVKETLQAMILQLQPAKEAGEREAAASCMTA 847
+ + LI + L ++ ++ ++ +I + + A+E ++ + M A
Sbjct: 1721 TQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMA 1769
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 51.2 bits (121), Expect = 4e-06
Identities = 103/439 (23%), Positives = 176/439 (40%), Gaps = 66/439 (15%)
Query: 451 SITRRDWLLQEKQQLQKEIE----------ALQARMFVLEAKDQQLRREIEEQEQQ---- 496
S+ +++ L+++Q + E+E + +A L+A+ Q+L+ +EE +QQ
Sbjct: 278 SLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLA 337
Query: 497 ----------LQWQGCDLTPLVGQLSLGQLQEVSKA-----LQDTLASAGQIPFHAEPPE 541
GC L +L G L + KA LQ L + AE +
Sbjct: 338 AQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQ 397
Query: 542 TIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHF 601
T S ++R++ L+L L E K+ S+K L+K V + + ++ +L+ H
Sbjct: 398 T--SNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGS 455
Query: 602 WTAK---DLTEEIRSLTSEREGL----------EGLLSKLLVLSSRNVKKL----GSVKE 644
K DL E + L +RE L EG L L + K L ++E
Sbjct: 456 IKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEE 515
Query: 645 DYNRLRREVEHQETAYETSV-KENT-MKYMETLKNKLCSCKCPLLGKVWEAD--LEACRL 700
+ LR E++ T E+S+ K NT + ++ L ++ K L+ + D L+ +
Sbjct: 516 ENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKH 575
Query: 701 LIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSL 760
+Q+ +EA +LS + DDL A + + L +E K L
Sbjct: 576 YLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQL---- 631
Query: 761 HCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKE 820
EE I E +K +KL + +H+ D+ L + + LQ K+
Sbjct: 632 --------EEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQ 683
Query: 821 TLQAMILQLQPAKEAGERE 839
L++ AKE RE
Sbjct: 684 --HQNDLKMLAAKEEQLRE 700
Score = 30.4 bits (67), Expect = 7.3
Identities = 17/43 (39%), Positives = 29/43 (67%), Gaps = 2/43 (4%)
Query: 780 EKCEDIGKKLLYLEDQLHT-AIHSHD-EDLIQSLRRELQMVKE 820
E+CEDI K L +L++Q + +H + ++L++ LR EL+ V E
Sbjct: 154 EECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE 196
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 51.2 bits (121), Expect = 4e-06
Identities = 103/439 (23%), Positives = 176/439 (40%), Gaps = 66/439 (15%)
Query: 451 SITRRDWLLQEKQQLQKEIE----------ALQARMFVLEAKDQQLRREIEEQEQQ---- 496
S+ +++ L+++Q + E+E + +A L+A+ Q+L+ +EE +QQ
Sbjct: 423 SLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLA 482
Query: 497 ----------LQWQGCDLTPLVGQLSLGQLQEVSKA-----LQDTLASAGQIPFHAEPPE 541
GC L +L G L + KA LQ L + AE +
Sbjct: 483 AQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQ 542
Query: 542 TIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHF 601
T S ++R++ L+L L E K+ S+K L+K V + + ++ +L+ H
Sbjct: 543 T--SNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGS 600
Query: 602 WTAK---DLTEEIRSLTSEREGL----------EGLLSKLLVLSSRNVKKL----GSVKE 644
K DL E + L +RE L EG L L + K L ++E
Sbjct: 601 IKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEE 660
Query: 645 DYNRLRREVEHQETAYETSV-KENT-MKYMETLKNKLCSCKCPLLGKVWEAD--LEACRL 700
+ LR E++ T E+S+ K NT + ++ L ++ K L+ + D L+ +
Sbjct: 661 ENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKH 720
Query: 701 LIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSL 760
+Q+ +EA +LS + DDL A + + L +E K L
Sbjct: 721 YLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQL---- 776
Query: 761 HCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKE 820
EE I E +K +KL + +H+ D+ L + + LQ K+
Sbjct: 777 --------EEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQ 828
Query: 821 TLQAMILQLQPAKEAGERE 839
L++ AKE RE
Sbjct: 829 --HQNDLKMLAAKEEQLRE 845
Score = 30.4 bits (67), Expect = 7.3
Identities = 17/43 (39%), Positives = 29/43 (67%), Gaps = 2/43 (4%)
Query: 780 EKCEDIGKKLLYLEDQLHT-AIHSHD-EDLIQSLRRELQMVKE 820
E+CEDI K L +L++Q + +H + ++L++ LR EL+ V E
Sbjct: 299 EECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE 341
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 50.8 bits (120), Expect = 5e-06
Identities = 92/406 (22%), Positives = 167/406 (41%), Gaps = 84/406 (20%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
+E +++E E + + EAK R+E+EE+ L + DL QLQ
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAK----RKELEEKMVTLMQEKNDL----------QLQVQ 896
Query: 520 SKALQDTLASAGQ-----IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTL 574
++A D+LA A + I + I+ + ER + E+T K E CS L
Sbjct: 897 AEA--DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSEL 954
Query: 575 RKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSR 634
+K ++D+E L A +E + HA ++++LT E GL+ ++KL
Sbjct: 955 KKDIDDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDETIAKL------ 996
Query: 635 NVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEAD 694
K+ +++E HQ+T + +E+ + + K KL L E
Sbjct: 997 -TKEKKALQE---------AHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL-----EGS 1041
Query: 695 LEACRLLIQSLQ--LQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEW 752
LE + + L+ ++ G L + E M D+E + +L ++ + L+
Sbjct: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTM-DIENDKQQLDEKLKKKEFEMSGLQ----- 1095
Query: 753 KTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHT--AIHSHDEDLIQS 810
+ E+ L +L +K +++ ++ LE+++ A + E
Sbjct: 1096 -------------SKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 811 LRRELQMVKETLQ----AMILQLQPAKEAGEREAAASCMTAGVHEA 852
L REL+ + E L+ A Q++ K +REA M + EA
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIEMNK---KREAEFQKMRRDLEEA 1185
Score = 50.1 bits (118), Expect = 9e-06
Identities = 104/569 (18%), Positives = 244/569 (42%), Gaps = 97/569 (17%)
Query: 357 LQKLQEDAVENDDYDKAET-LQQRLEDLE-----QEKISLHFQLPSRQPALSSFLGHLAA 410
L LQ + + + KA+ L+Q+++DLE ++KI + + R+
Sbjct: 1011 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRK-----------L 1059
Query: 411 QVQAALRRGATQQASGDDTHTPLRMEPRLLEPTA-------QDSLHVSITRRDWLLQEK- 462
+ L + +T D +++ + E + + +L + + ++ LQ +
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 463 QQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLV--GQLSLGQLQEVS 520
++L++EIEA +A E + L RE+EE ++L+ G + + + + Q++
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 521 KALQDTLA--SAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKV 578
+ L++ A + +++ L E+I +L +++ EK S ++ ++
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL-------EKEKSEMKMEI 1232
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
+D+ + + + +AK GN + L +++ + ++ E + L++ L +R +
Sbjct: 1233 DDLASNMETVSKAK-----GNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
Query: 639 LGSVK---EDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSC--------KCPLL 687
G ++ + L ++ + A+ ++E + E +K K C LL
Sbjct: 1288 SGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLL 1347
Query: 688 GKVWEADLEACRLLIQSL-----QLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDK- 741
+ +E + EA L +++ ++ + R + ++ ++LE A + RL ++
Sbjct: 1348 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEH 1407
Query: 742 -----------RKTPLKVLEEWKTHLI----PSLHCAGGEQKEESY-ILSAELGEKCEDI 785
KT ++ E + +I + CA ++K+ ++ + AE +KCE+
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1467
Query: 786 -------GKKLLYLEDQLHTAIHSHDE--DLIQSLRRELQMVKETLQAMILQLQPAKEAG 836
K+ L +L ++++E D +++L+RE + +++ + + Q+ E G
Sbjct: 1468 HAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI---AEGG 1524
Query: 837 ER-----------EAAASCMTAGVHEAQA 854
+R E S + A + EA+A
Sbjct: 1525 KRIHELEKIKKQVEQEKSELQAALEEAEA 1553
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 50.4 bits (119), Expect = 7e-06
Identities = 127/608 (20%), Positives = 236/608 (38%), Gaps = 72/608 (11%)
Query: 278 AQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPV- 336
AQA+ NSS P R + + LD G + SGD S+ L+ P
Sbjct: 23 AQASSNSSTPTR----MRSRTSSFTEQLDE------GTPNRESGDTQSFAQKLQLRVPSV 72
Query: 337 -------LRDCLLRNRRQMEVI--SLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEK 387
+++ L R+ + ++ S R L +L D+ +D + EDL
Sbjct: 73 ESLFRSPIKESLFRSSSKESLVRTSSRESLNRLDLDS-STASFDPPSDMDSEAEDLVGNS 131
Query: 388 ISLHFQ-----LPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEP 442
SL+ + L + +LSS+ G + V A + L+ E + L+
Sbjct: 132 DSLNKEQLIQRLRRMERSLSSYRGKYSELVTA---------------YQMLQREKKKLQG 176
Query: 443 TAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFV-LEAKDQQ---LRREIEEQEQQLQ 498
S S+ R L +E Q Q+ + LQ LE KDQ L+ ++ +Q+L+
Sbjct: 177 ILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLR 236
Query: 499 WQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLK 558
++ L L EV ++ + + +T+ +LQ+R+K LK
Sbjct: 237 NGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLK 296
Query: 559 EITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSER 618
+ ++ C+ L + ++ QL L+ ++ I H L ++R +
Sbjct: 297 RCKETIQSHKEQCTLLTSEKEALQEQLDERLQ-ELEKIKDLHMAEKTKLITQLRDAKNLI 355
Query: 619 EGLEGLLSKLLVLSSRNVKKLGSVKEDY-----NRLRREVEHQETAYETSVKENTMKYME 673
E LE ++ + R + + +KE+ +R+++ E E K + E
Sbjct: 356 EQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEE 415
Query: 674 TLKNKLCSCKCPLLGKVWEADLEACRLLIQ--------SLQLQEARGSLSVEDERQMDDL 725
K + K + +A+++ I+ SLQ + +R V D +
Sbjct: 416 LEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSE 475
Query: 726 EGAAPPIPPRLHSED---KRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKC 782
E A +LH ++ K + K L+ + + A E+ + Y+ ++ E+
Sbjct: 476 EQIAKL--QKLHEKELARKEQELTKKLQTREREFQEQMKVAL-EKSQSEYLKISQEKEQQ 532
Query: 783 EDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAAA 842
E + + L L+ + AI + E+ + R+LQ ET + IL+L+ + E +E
Sbjct: 533 ESLALEELELQKK---AILTESENKL----RDLQQEAETYRTRILELESSLEKSLQENKN 585
Query: 843 SCMTAGVH 850
VH
Sbjct: 586 QSKDLAVH 593
Score = 45.1 bits (105), Expect = 3e-04
Identities = 109/537 (20%), Positives = 209/537 (38%), Gaps = 81/537 (15%)
Query: 347 QMEVISLRLKLQKLQEDAVENDDYDKA-ETLQQRLEDLE------QEKISLHFQ----LP 395
Q EV + + E VE+ K ETLQQR++ E +E I H + L
Sbjct: 254 QAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLT 313
Query: 396 SRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR 455
S + AL L ++Q + A T LR L+E QD V +
Sbjct: 314 SEKEALQE---QLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK 370
Query: 456 DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQ 515
+ + + ++EI L++R+ + + ++LR + E+ E+
Sbjct: 371 RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSER------------------AA 412
Query: 516 LQEVSKALQDT-LASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCM-------- 566
+E+ KAL + AE E I+++++ + +SL++ ++V
Sbjct: 413 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK 472
Query: 567 -SEKFCSTLR----KKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGL 621
SE+ + L+ K++ E +L L+ + + E ++ E+E
Sbjct: 473 SSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532
Query: 622 EGLLSKLLVLSSRNV-----KKLGSVKEDYNRLRREVEHQETAYETSVKENTMK------ 670
E L + L L + + KL ++++ R + E++ E S++EN +
Sbjct: 533 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592
Query: 671 YMETLKNKLCSCKCPLLGK--------------VWEADLEACRLLIQSLQLQEARGSLSV 716
++E KNK ++ K +W L+ + Q+ ++++ R
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQT-EMEKLREKCEQ 651
Query: 717 EDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSA 776
E E + D E I + H E+ + L+ L+ +T L SL E + + L
Sbjct: 652 EKETLLKDKE-----IIFQAHIEEMNEKTLEKLDVKQTEL-ESLSSELSEVLKARHKLEE 705
Query: 777 ELGEKCEDIGKKLLYLEDQLHTAIHSHD---EDLIQSLRRELQMVKETLQAMILQLQ 830
EL + K LE ++ + H + +I+ +Q ++ L+ I QL+
Sbjct: 706 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/391 (19%), Positives = 155/391 (39%), Gaps = 59/391 (15%)
Query: 376 LQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAA---QVQAALRRGATQQASGDDTHTP 432
LQQ+L DLE E+I L Q+ + L A QVQ +++ Q + +
Sbjct: 824 LQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883
Query: 433 LRM--EPRLLEPTAQD--SLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRR 488
L E +L + + + + + + + +LQ ++ +KEIE L + L AK+ +
Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQK---LSAKEDSIHI 940
Query: 489 EIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASA---GQIPFHAEPPETIRS 545
EE E + + Q + + ++++ +K +Q+TL + E T
Sbjct: 941 LNEEYETKFKNQ---------EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 546 LQERIKSLNLSLKEI----------------TTKVCMSEKFCSTLRKKVNDIETQLPALL 589
L ++ K N + E+ T + E R+++ND+ + L
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKL 1051
Query: 590 EAKMHAISGNHFWTAKDLTEEIRSLTS-------EREGL---------EGL-----LSKL 628
+ + H ++ +E+ L E+E + EG+ L++L
Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1111
Query: 629 LVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLG 688
+ + S+ +D +L+ +E E S+KENT + ++ K+ + +
Sbjct: 1112 QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKV 1171
Query: 689 KVWEADLEACRLLIQSLQLQEARGSLSVEDE 719
+ L+ QSL+ + + S+ED+
Sbjct: 1172 SELTSKLKTTDEEFQSLKSSHEKSNKSLEDK 1202
Score = 39.3 bits (90), Expect = 0.016
Identities = 87/419 (20%), Positives = 173/419 (41%), Gaps = 95/419 (22%)
Query: 458 LLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEE-------QEQQLQWQGCDLTPLVGQ 510
L+ EK+ LQKE Q E+ QL++E+ E +++L+ + +++ L Q
Sbjct: 1316 LVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ 1375
Query: 511 LS---------------------------------LGQLQEVSKAL----QDTLASAGQI 533
L+ L Q+Q++S + ++ +++ Q+
Sbjct: 1376 LTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQV 1435
Query: 534 -PFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPA----- 587
+ + E + Q R ++KE+ ++ + K +++N ++ +L
Sbjct: 1436 DDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRF 1495
Query: 588 -LLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDY 646
L+ +M +L E++S T+ LE +++ + ++ L V ++Y
Sbjct: 1496 DCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTI----EIESLNEVLKNY 1551
Query: 647 NRLRREVEHQETAYET-------SVKENTMKYME----TLKNKLCSCKCPLLGKVWEADL 695
N+ ++++EH+E + K+N +K E TL+N++ S K L K + +L
Sbjct: 1552 NQ-QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETK--KKEL 1608
Query: 696 EACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRK-TPLKVLEEWKT 754
E L ++S + E+ + ++D RL SE K LK E K
Sbjct: 1609 EHVNLSVKSKE----------EELKALED----------RLESESAAKLAELKRKAEQKI 1648
Query: 755 HLIPSLHCAGGEQKEESYILS-----AELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLI 808
I + E+KEE Y +EL K ++ +++ LE++L + S E LI
Sbjct: 1649 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLI 1707
Score = 34.3 bits (77), Expect = 0.50
Identities = 57/283 (20%), Positives = 114/283 (40%), Gaps = 54/283 (19%)
Query: 420 ATQQASGDDTHTPL-------RMEPRLLEPTAQDSLHVSITRRDWLL----QEKQQLQKE 468
A QQ G + T L + + L++P ++ ++ L +EKQ+L KE
Sbjct: 1886 ALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKE 1945
Query: 469 IEALQARMFVLEAKDQQ----LRREIEEQEQQLQWQGCDLTPLVGQLSLGQL-------- 516
I LQ + +L + QQ L++E +++ ++ Q + L +L QL
Sbjct: 1946 IVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQL 2005
Query: 517 ----QEVSKALQDTLASAGQI------PFHAEPPETIRSLQERIKSLNLSLKEITTKVCM 566
QE+ +++T+ A ++ E + ++ + E+ L + K +
Sbjct: 2006 AQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA 2065
Query: 567 SEKFCSTLRKKVNDIETQLPALLEAKMHAIS-----GNHFWTAKDLTEEIRSLTSEREGL 621
E+ + KV D++TQL L + + GN T +L +
Sbjct: 2066 REE---EMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQ----------- 2111
Query: 622 EGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSV 664
L K ++S +K+ ++ +N R ++++ Y T+V
Sbjct: 2112 --LAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTV 2152
Score = 34.3 bits (77), Expect = 0.50
Identities = 49/206 (23%), Positives = 96/206 (46%), Gaps = 12/206 (5%)
Query: 349 EVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHL 408
E++ L+ L+ L+++ + + K E Q+R E ++QE+ L + S L
Sbjct: 1945 EIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQ 2004
Query: 409 AAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDS--LHVSITRRDWLLQEKQQLQ 466
AQ + L + + + +E LLE +++ L I +D L+ +
Sbjct: 2005 LAQKEQEL-----EMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRY 2059
Query: 467 KEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQ-GCDLTPLVGQLSLGQLQEVSKALQD 525
+EI L AR + AK + L+ ++EE +++ Q + + P +++ +LQ A +
Sbjct: 2060 EEI--LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQ-TQLAQKT 2116
Query: 526 TLASAGQIPFHAEPPETIRSLQERIK 551
TL S ++ E E I +L++R+K
Sbjct: 2117 TLISDSKLK-EQEFREQIHNLEDRLK 2141
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 50.4 bits (119), Expect = 7e-06
Identities = 107/536 (19%), Positives = 234/536 (43%), Gaps = 74/536 (13%)
Query: 357 LQKLQEDAVENDDYDKAET-LQQRLEDLE----QEKISLHFQLPSRQPALSSFLGHLAAQ 411
L LQ + + + KA+ L+Q+++DLE QEK L L + L L
Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK-KLRMDLERAKRKLEGDL----KL 1067
Query: 412 VQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQD--SLHVSITRRDWLLQEK-QQLQKE 468
Q ++ ++ D+ E L+ +D +L + + ++ LQ + ++L++E
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 469 IEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLV--GQLSLGQLQEVSKALQDT 526
IEA +A E + L RE+EE ++L+ G + + + + Q++ + L++
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 527 LA--SAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQ 584
A + +++ L E+I +L +++ EK S ++ +++D+ +
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL-------EKEKSEMKMEIDDLASN 1240
Query: 585 LPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVK- 643
+ + +AK GN + L +++ L S+ E + L++ L R + G
Sbjct: 1241 VETVSKAK-----GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295
Query: 644 --EDYNRLRREVEHQETAYETSVKENTMKYMETLKNK------LCSCK--CPLLGKVWEA 693
++ L ++ + A+ ++E + E +K K L S + C LL + +E
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 694 DLEACRLLIQSL-----QLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKV 748
+ E+ L ++L ++ + R + ++ ++LE A + RL + ++ +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 749 ----LEEWKTHLIPSLH------------CAGGEQKEESY-ILSAELGEKCEDI------ 785
LE+ K L + CA ++K+ ++ + AE +KCE+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 786 -GKKLLYLEDQLHTAIHSHDE--DLIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
K+ L +L ++++E D +++L+RE + +++ + + Q+ E G+R
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI---AEGGKR 1528
Score = 50.1 bits (118), Expect = 9e-06
Identities = 92/406 (22%), Positives = 163/406 (40%), Gaps = 84/406 (20%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
+E +++E + ++ + EAK R+E+EE+ L + DL QL Q+Q
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAK----RKELEEKMVTLLKEKNDL-----QL---QVQAE 900
Query: 520 SKALQDTLASAGQ-IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKV 578
++ L D Q I + I+ + ER + E+T K E CS L+K +
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
+D+E L A +E + HA ++++LT E GL+ ++KL K+
Sbjct: 961 DDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDETIAKL-------TKE 1001
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEAC 698
+++E HQ+T + +E+ + + K KL
Sbjct: 1002 KKALQE---------AHQQTLDDLQAEEDKVNTLTKAKIKL------------------- 1033
Query: 699 RLLIQSLQLQEARGSLSVEDERQMD------DLEGAAPPIPPRLHSEDKRKTPLKVLEEW 752
Q+ + GSL E + +MD LEG + + K L +
Sbjct: 1034 -----EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 753 KTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHT--AIHSHDEDLIQS 810
K I +L + E+ L +L +K +++ ++ LE+++ A + E
Sbjct: 1089 KEFEISNLQ----SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 811 LRRELQMVKETLQ----AMILQLQPAKEAGEREAAASCMTAGVHEA 852
L REL+ + E L+ A Q++ K +REA M + EA
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNK---KREAEFQKMRRDLEEA 1187
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 50.4 bits (119), Expect = 7e-06
Identities = 107/536 (19%), Positives = 234/536 (43%), Gaps = 74/536 (13%)
Query: 357 LQKLQEDAVENDDYDKAET-LQQRLEDLE----QEKISLHFQLPSRQPALSSFLGHLAAQ 411
L LQ + + + KA+ L+Q+++DLE QEK L L + L L
Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK-KLRMDLERAKRKLEGDL----KL 1067
Query: 412 VQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQD--SLHVSITRRDWLLQEK-QQLQKE 468
Q ++ ++ D+ E L+ +D +L + + ++ LQ + ++L++E
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 469 IEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLV--GQLSLGQLQEVSKALQDT 526
IEA +A E + L RE+EE ++L+ G + + + + Q++ + L++
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 527 LA--SAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQ 584
A + +++ L E+I +L +++ EK S ++ +++D+ +
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL-------EKEKSEMKMEIDDLASN 1240
Query: 585 LPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVK- 643
+ + +AK GN + L +++ L S+ E + L++ L R + G
Sbjct: 1241 VETVSKAK-----GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295
Query: 644 --EDYNRLRREVEHQETAYETSVKENTMKYMETLKNK------LCSCK--CPLLGKVWEA 693
++ L ++ + A+ ++E + E +K K L S + C LL + +E
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 694 DLEACRLLIQSL-----QLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKV 748
+ E+ L ++L ++ + R + ++ ++LE A + RL + ++ +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 749 ----LEEWKTHLIPSLH------------CAGGEQKEESY-ILSAELGEKCEDI------ 785
LE+ K L + CA ++K+ ++ + AE +KCE+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 786 -GKKLLYLEDQLHTAIHSHDE--DLIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
K+ L +L ++++E D +++L+RE + +++ + + Q+ E G+R
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI---AEGGKR 1528
Score = 50.1 bits (118), Expect = 9e-06
Identities = 92/406 (22%), Positives = 163/406 (40%), Gaps = 84/406 (20%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
+E +++E + ++ + EAK R+E+EE+ L + DL QL Q+Q
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAK----RKELEEKMVTLLKEKNDL-----QL---QVQAE 900
Query: 520 SKALQDTLASAGQ-IPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKV 578
++ L D Q I + I+ + ER + E+T K E CS L+K +
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
+D+E L A +E + HA ++++LT E GL+ ++KL K+
Sbjct: 961 DDLELTL-AKVEKEKHATE-----------NKVKNLTEEMAGLDETIAKL-------TKE 1001
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEAC 698
+++E HQ+T + +E+ + + K KL
Sbjct: 1002 KKALQE---------AHQQTLDDLQAEEDKVNTLTKAKIKL------------------- 1033
Query: 699 RLLIQSLQLQEARGSLSVEDERQMD------DLEGAAPPIPPRLHSEDKRKTPLKVLEEW 752
Q+ + GSL E + +MD LEG + + K L +
Sbjct: 1034 -----EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 753 KTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHT--AIHSHDEDLIQS 810
K I +L + E+ L +L +K +++ ++ LE+++ A + E
Sbjct: 1089 KEFEISNLQ----SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1144
Query: 811 LRRELQMVKETLQ----AMILQLQPAKEAGEREAAASCMTAGVHEA 852
L REL+ + E L+ A Q++ K +REA M + EA
Sbjct: 1145 LSRELEEISERLEEAGGATSAQIEMNK---KREAEFQKMRRDLEEA 1187
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 50.4 bits (119), Expect = 7e-06
Identities = 113/522 (21%), Positives = 214/522 (40%), Gaps = 58/522 (11%)
Query: 361 QEDAVENDDYDKAET----LQQRLEDLEQEKISLHFQLPSRQPALSSFLGHL-AAQVQAA 415
+ +E + +K E LQQ L+ L ++K+SLH + + Q L + + Q + A
Sbjct: 1815 ENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELA 1874
Query: 416 LRRGATQQASGDDTHTPLRMEPRLLEPT-AQDSLHVSITR-------RDWLLQEKQQLQK 467
+ A D HT + L E T Q + R + Q+ Q LQ
Sbjct: 1875 NVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQN 1934
Query: 468 EIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTL 527
EIE + ++ E Q+L++E E +E +L+ L Q ++ K L D
Sbjct: 1935 EIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKE--------QQHQLEKELTDQK 1986
Query: 528 ASAGQIPFHA-EPPETIRSLQER---IKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIET 583
+ Q+ E +R+LQE +SL +L + TK +SE+ + K +
Sbjct: 1987 SKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQ--TKRQLSEREQQLVEKSGELLAL 2044
Query: 584 QLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVK 643
Q A ++ N F T + E + + S +E L+ + S+ K L K
Sbjct: 2045 QKEADSMRADFSLLRNQFLTERKKAE--KQVASLKEALK-------IQRSQLEKNLLEQK 2095
Query: 644 EDYNRLRREV--------EHQETAYETSVKENTMKYMET-LKNKLCSCKCPLLGKVWEAD 694
++ + +++E+ ++ E A + N M+Y T LK ++ + K D
Sbjct: 2096 QENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQK----------D 2145
Query: 695 LEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLK-VLEEWK 753
LE ++ I S ++ + + E + +L P +P L + +R L+ LE K
Sbjct: 2146 LERRQMEI-SDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLK 2204
Query: 754 THLIPSLHCAGGEQK-EESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLR 812
+L +++ E+K S + + + E + +KL + ED+L + + L
Sbjct: 2205 ENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLI 2264
Query: 813 RELQMVKETLQAMILQLQPAKEAGEREAAASCMTAGVHEAQA 854
+ + + TL ++ Q+ E +A S + + + ++
Sbjct: 2265 KGKRQTEGTLHSLRRQVDALGELVTSTSADSASSPSLSQLES 2306
Score = 40.0 bits (92), Expect = 0.009
Identities = 109/581 (18%), Positives = 225/581 (38%), Gaps = 115/581 (19%)
Query: 356 KLQKLQED---AVENDDYD----------------KAETLQQRLEDLEQEKISLHFQLPS 396
+LQKLQ+D A N+D+ + E L+ ++ +QE L QL
Sbjct: 1546 ELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGH 1605
Query: 397 RQPALSSFLGHLA---AQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTA--QDSLHVS 451
++ L G + A +Q ALR G T+ + +R LLE + + L+V
Sbjct: 1606 KKEELHLLQGSMVQAKADLQEALRLGETEVT---EKCNHIREVKSLLEELSFQKGELNVQ 1662
Query: 452 IT-RRDWLLQEKQQLQKEIEALQA------------------------------------ 474
I+ R+ L KQ+++KE E LQ
Sbjct: 1663 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQR 1722
Query: 475 -------RMFVLEAKDQ--QLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQD 525
++ VLE K + L++ ++Q+ +++WQ QL +E+ + +
Sbjct: 1723 VSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQ--------KQLLERDKREIERMTAE 1774
Query: 526 TLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQL 585
+ A + ++ E LQE+ L + + +E+ + + +E +
Sbjct: 1775 SRALQSCVECLSKEKE---DLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNV 1831
Query: 586 PALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKL------LVLSSRNV--- 636
L+ ++ ++ + D++ + L +RE + L +L L L+ +++
Sbjct: 1832 -RKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHT 1890
Query: 637 -KKLGSVKEDYNRLRREVEHQETAYETSVKENTMK--YMETLKNKLCSCKCPLLGKVW-- 691
K + + RL++++ +E KE K ++ L+N++ K L+ +
Sbjct: 1891 TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMF 1950
Query: 692 -----EADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPL 746
E + E +L + L+E + L E+++ D + + ++ + ++R L
Sbjct: 1951 QRLQKERESEESKLETSKVTLKEQQHQL----EKELTDQKSKLDQVLSKVLAAEERVRTL 2006
Query: 747 KVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE------KCEDIGKKLLYLEDQLHTAI 800
+ E W L +L + E L + GE + + + L +Q T
Sbjct: 2007 QEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE- 2065
Query: 801 HSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAA 841
E + SL+ L++ + L+ +L+ + ++E A
Sbjct: 2066 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMA 2106
Score = 37.0 bits (84), Expect = 0.078
Identities = 93/490 (18%), Positives = 198/490 (40%), Gaps = 67/490 (13%)
Query: 371 DKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALR-----RGATQQAS 425
D+ ETL QRL ++EQE+ L + A++++AL+ + QQ
Sbjct: 644 DEKETLLQRLTEVEQERDQLEIVAMDAENMRKEL-----AELESALQEQHEVNASLQQTQ 698
Query: 426 GDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQ 485
GD + +E RL RD E QL++E+E + R+ LE
Sbjct: 699 GDLSAYEAELEARL-------------NLRD---AEANQLKEELEKV-TRLTQLE--QSA 739
Query: 486 LRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRS 545
L+ E+E++ Q L + +LG+ Q + Q+ ++ H + +
Sbjct: 740 LQAELEKERQAL------------KNALGKAQFSEEKEQENSELHAKLK-HLQDDNNL-- 784
Query: 546 LQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLP-ALLEAKMHAISGNHFWTA 604
L++++K L + + E+ + +V+++ +L E +H+ S +
Sbjct: 785 LKQQLKDFQNHLNHVVDGLVRPEEVAA----RVDELRRKLKLGTGEMNIHSPSDVLGKSL 840
Query: 605 KDLTEEIRSLTS----EREGLEGLLSKLLVLSSRNVKKLGSVKEDYNR-----LRREVEH 655
DL ++ + + ER+ + KL + +KL + +E++ + L +
Sbjct: 841 ADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNF 900
Query: 656 QETAYETSVK--ENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGS 713
+ +E ++ EN + Y++ + + ++ EAD E R+L Q +L++ +
Sbjct: 901 DKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKL 960
Query: 714 LSVEDERQMDDLEGAAPPIPPRLHSEDKRKT-PLKVLEEWKTHL---IPSLHCAGGEQKE 769
+ + Q+ L+ + + + DK T L + ++ L + ++ E+ +
Sbjct: 961 EDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQ 1020
Query: 770 ESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQL 829
E+ S + + D+ + +E L + E L E V + +L++
Sbjct: 1021 EAERFSRKAAQAARDLTRAEAEIE-LLQNLLRQKGEQF--RLEMEKTGVGTGANSQVLEI 1077
Query: 830 QPAKEAGERE 839
+ E ER+
Sbjct: 1078 EKLNETMERQ 1087
Score = 36.6 bits (83), Expect = 0.10
Identities = 80/427 (18%), Positives = 170/427 (39%), Gaps = 72/427 (16%)
Query: 430 HTPLRMEPRLLEPTAQDSLHVSITRRD--WLLQEKQQLQKEIEALQARM-------FVLE 480
H L E LE Q H+ +R+ W+ K+Q +KE+E L + LE
Sbjct: 1318 HHNLENEVSRLEDIMQ---HLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLE 1374
Query: 481 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 540
+ ++L R +++++QQ + ++ L+ +L E+ K+L+ H +
Sbjct: 1375 CEVEELHRTVQKRQQQKDFIDGNVESLMTEL------EIEKSLK----------HHEDIV 1418
Query: 541 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 600
+ I +++ + L+E + +E S ++K + +
Sbjct: 1419 DEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKF--------------- 1463
Query: 601 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 660
D + S+ E LE + V + ++L S++ D +++E +
Sbjct: 1464 ----TDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQAD----AKDLEQHKIKQ 1515
Query: 661 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER 720
E +KE + + K+ C L K E E + L + +++ E ++ +
Sbjct: 1516 EEILKE--INKIVAAKDSDFQC----LSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLK 1569
Query: 721 QMDDLEGAAPPIPPRLHSE-DKRKTPLKVLEEWKTHLIPSLHCAGG-------EQKEESY 772
+ + L A +L S+ ++ + VL+ H LH G + +E
Sbjct: 1570 ESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALR 1629
Query: 773 ILSAELGEKCEDIG------KKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMI 826
+ E+ EKC I ++L + + +L+ I S + + +++E++ +E LQ ++
Sbjct: 1630 LGETEVTEKCNHIREVKSLLEELSFQKGELNVQI-SERKTQLTLIKQEIEKEEENLQVVL 1688
Query: 827 LQLQPAK 833
Q+ K
Sbjct: 1689 RQMSKHK 1695
Score = 35.0 bits (79), Expect = 0.30
Identities = 85/422 (20%), Positives = 172/422 (40%), Gaps = 67/422 (15%)
Query: 449 HVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLV 508
H+++ L + + +K+I A Q R+ +L EIE+ EQQ+ + L
Sbjct: 426 HMNLRGHTPLDTQLEDKEKKISAAQTRL-------SELHDEIEKAEQQILRATEEFKQLE 478
Query: 509 GQLSLGQLQEVSKALQDTLAS--AGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCM 566
+ QL+++S+A +D L +G++ + + L++ L L +++ ++
Sbjct: 479 EAI---QLKKISEAGKDLLYKQLSGRL-------QLVNKLRQEALDLELQMEKQKQEIAG 528
Query: 567 SEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLS 626
+K L+ ++ ++++ P K SG +++ + + + LE L
Sbjct: 529 KQKEIKDLQIAIDSLDSKDPKHSHMKAQK-SGKE--------QQLDIMNKQYQQLESRLD 579
Query: 627 KLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKE------NTMKYMETLK---- 676
++L SR K+ +K+ +L E Q A E K+ +Y+ T+K
Sbjct: 580 EIL---SRIAKETEEIKDLEEQL---TEGQIAANEALKKDLEGVISGLQEYLGTIKGQAT 633
Query: 677 ------NKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSL-----SVEDERQMD-- 723
KL K LL ++ E + E +L I ++ + R L +++++ +++
Sbjct: 634 QAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNAS 693
Query: 724 ------DLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCA-GGEQKEESYILSA 776
DL + RL+ D LK E T L A E ++E L
Sbjct: 694 LQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKN 753
Query: 777 ELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAG 836
LG+ ++ +LH + H +D L+++L+ + L ++ L +E
Sbjct: 754 ALGK--AQFSEEKEQENSELHAKL-KHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVA 810
Query: 837 ER 838
R
Sbjct: 811 AR 812
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/319 (22%), Positives = 140/319 (43%), Gaps = 41/319 (12%)
Query: 429 THTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRR 488
T L ME LLE DSL ++R + + ++ +KEI AL++ + L+ + +L++
Sbjct: 763 TEKKLEMEKLLLE---NDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKK 819
Query: 489 EIEEQEQQLQWQGCDLTPLVGQLS-----LGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
+ E ++++ + T L +S + +EV L DTLA + +
Sbjct: 820 KCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNR---------EL 870
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALL--EAKMHAISGNHF 601
++++ + +N +I K +E L N I+ + +L EAKM ++S
Sbjct: 871 LDVKKKFEDINQEFVKIKDK---NEILKRNLENTQNQIKAEYISLAEHEAKMSSLS-QSM 926
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKE----------DYNRLRR 651
+D EI L + R+G E +++ + ++ K+L +++E + R
Sbjct: 927 RKVQDSNAEI--LANYRKGQEEIVTLHAEIKAQK-KELDTIQECIKVKYAPIVSFEECER 983
Query: 652 EVEHQETAYETSVKENTMKYM----ETLKNKLCSCKCPLLGKVWEADLEACRLLIQ-SLQ 706
+ + E + + E T KY E KNK + K + DL +LI+ S +
Sbjct: 984 KFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHE 1043
Query: 707 LQEARGSLSVEDERQMDDL 725
++ A + E +Q+ DL
Sbjct: 1044 MERALSRKTDELNKQLKDL 1062
Score = 30.8 bits (68), Expect = 5.6
Identities = 59/306 (19%), Positives = 128/306 (41%), Gaps = 34/306 (11%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
++ +QL+ ++ +Q RM+ E K +Q++ ++ L + + + QL+++
Sbjct: 477 EQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDL 536
Query: 520 SKALQDTLASAGQIPFHAEPPETIRSLQERIK-SLNLSLKEITTKVCMSEKFCSTLRKKV 578
+ A G++ + E I +R + L K + ++ M E +KV
Sbjct: 537 KVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKV 596
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
++E Q L +I F K SL++E + KL+ + + K
Sbjct: 597 TEMEGQAKELSAKLALSIPAEKFENMKS------SLSNE---VNEKAKKLVEMEREHEKS 647
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADL--- 695
L +++ L+RE+E+ + VK + E +K++L L K+ E L
Sbjct: 648 LSEIRQ----LKRELENVKAKLAQHVKP---EEHEQVKSRLEQKSGELGKKITELTLKNQ 700
Query: 696 ----EACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEE 751
E ++ + + L+E +L++E + +P ++ SED +K+ ++++
Sbjct: 701 TLQKEIEKVYLDNKLLKEQAHNLTIEMKNHY---------VPLKV-SEDMKKSHDAIIDD 750
Query: 752 WKTHLI 757
L+
Sbjct: 751 LNRKLL 756
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/319 (22%), Positives = 140/319 (43%), Gaps = 41/319 (12%)
Query: 429 THTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRR 488
T L ME LLE DSL ++R + + ++ +KEI AL++ + L+ + +L++
Sbjct: 776 TEKKLEMEKLLLE---NDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKK 832
Query: 489 EIEEQEQQLQWQGCDLTPLVGQLS-----LGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
+ E ++++ + T L +S + +EV L DTLA + +
Sbjct: 833 KCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNR---------EL 883
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALL--EAKMHAISGNHF 601
++++ + +N +I K +E L N I+ + +L EAKM ++S
Sbjct: 884 LDVKKKFEDINQEFVKIKDK---NEILKRNLENTQNQIKAEYISLAEHEAKMSSLS-QSM 939
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKE----------DYNRLRR 651
+D EI L + R+G E +++ + ++ K+L +++E + R
Sbjct: 940 RKVQDSNAEI--LANYRKGQEEIVTLHAEIKAQK-KELDTIQECIKVKYAPIVSFEECER 996
Query: 652 EVEHQETAYETSVKENTMKYM----ETLKNKLCSCKCPLLGKVWEADLEACRLLIQ-SLQ 706
+ + E + + E T KY E KNK + K + DL +LI+ S +
Sbjct: 997 KFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHE 1056
Query: 707 LQEARGSLSVEDERQMDDL 725
++ A + E +Q+ DL
Sbjct: 1057 MERALSRKTDELNKQLKDL 1075
Score = 30.8 bits (68), Expect = 5.6
Identities = 59/306 (19%), Positives = 128/306 (41%), Gaps = 34/306 (11%)
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEV 519
++ +QL+ ++ +Q RM+ E K +Q++ ++ L + + + QL+++
Sbjct: 490 EQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDL 549
Query: 520 SKALQDTLASAGQIPFHAEPPETIRSLQERIK-SLNLSLKEITTKVCMSEKFCSTLRKKV 578
+ A G++ + E I +R + L K + ++ M E +KV
Sbjct: 550 KVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKV 609
Query: 579 NDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKK 638
++E Q L +I F K SL++E + KL+ + + K
Sbjct: 610 TEMEGQAKELSAKLALSIPAEKFENMKS------SLSNE---VNEKAKKLVEMEREHEKS 660
Query: 639 LGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADL--- 695
L +++ L+RE+E+ + VK + E +K++L L K+ E L
Sbjct: 661 LSEIRQ----LKRELENVKAKLAQHVKP---EEHEQVKSRLEQKSGELGKKITELTLKNQ 713
Query: 696 ----EACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEE 751
E ++ + + L+E +L++E + +P ++ SED +K+ ++++
Sbjct: 714 TLQKEIEKVYLDNKLLKEQAHNLTIEMKNHY---------VPLKV-SEDMKKSHDAIIDD 763
Query: 752 WKTHLI 757
L+
Sbjct: 764 LNRKLL 769
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 49.7 bits (117), Expect = 1e-05
Identities = 130/576 (22%), Positives = 229/576 (39%), Gaps = 113/576 (19%)
Query: 359 KLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQ--VQAAL 416
K +++ + +D + + L ++L+ LE+E+ + + L + L + +A+L
Sbjct: 386 KGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASL 445
Query: 417 RRGATQQA--------SGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQ--EKQQLQ 466
R + A G + R LL T+ ++ RR+ Q EK+ L+
Sbjct: 446 ERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLE 505
Query: 467 KEIEALQARMFVLEAKDQQLRR---EIEEQEQQLQWQGCDLTPLVGQLS----------- 512
+E+ +L ++ LE + Q+ + ++EEQ++QL L+ VG L
Sbjct: 506 QEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELP 565
Query: 513 -LGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFC 571
G+ E + +L A +P E R LQE L + + E+
Sbjct: 566 VAGEKNEALVPVNSSLQEAW-----GKPEEEQRGLQEA------QLDDTKVQEGSQEE-- 612
Query: 572 STLRKKVNDIETQLP------ALLEAKMHAISGNHFWTAKD---LTEEIRSLTSEREGLE 622
LR+ ++E +L LLE K+ A+ ++ + + + SL +E+ +
Sbjct: 613 -ELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIR 671
Query: 623 GL-----LSKLLVLSSRNVKK---------LGSVKEDYNRLRREVEHQETAYETSVKE-- 666
L S L V ++ K L S + + +LR EVE + E +E
Sbjct: 672 HLGDQMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELR 731
Query: 667 --NTMKYMETLKNKLCSCKCPLLGKVWEADLEA----CRLLIQSLQLQEARGSLSVEDER 720
+ +T ++ + + G D EA +L + QL+ +G + +
Sbjct: 732 ALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQ-RLQA 790
Query: 721 QMDDLEGAAPPIPPRLHSEDKRKTPLK----VLEEWKT---------------HLIPSLH 761
Q+ DL+ + L +DK ++ L VL E KT H+ L
Sbjct: 791 QVVDLQAK---MRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQ 847
Query: 762 CAGGE-------------QKEESYILSAELGE-KCEDIGKKLLY--LEDQLHTAIHSHDE 805
C+ E ++EE L EL + KC +L + L++QLH A E
Sbjct: 848 CSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAE 907
Query: 806 DLIQ--SLRRELQMVKETLQAMILQLQPAKEAGERE 839
IQ +L E + V+E L + +LQ AKEA RE
Sbjct: 908 LGIQVCALTVEKERVEEALACAVQELQDAKEAASRE 943
Score = 47.8 bits (112), Expect = 4e-05
Identities = 95/414 (22%), Positives = 175/414 (42%), Gaps = 66/414 (15%)
Query: 329 LLRKWEPVLRDCLLRNRRQMEVISLRLKLQKLQEDAVEND-DYDKA-ETLQQRLEDLEQE 386
L ++WE + Q V L+ LQ L+ A E + DY A L+ L+ L QE
Sbjct: 298 LQKQWE-------VTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQE 350
Query: 387 KISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQD 446
+ L + L+SF G LA Q A T+ EP D
Sbjct: 351 LEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQ---------------EPIPSD 395
Query: 447 SLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQG----- 501
+ QE Q+L ++++AL+ +E ++Q ++E+ ++LQ +
Sbjct: 396 A-----------AQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARAS 444
Query: 502 -----CDLTPLVGQLSLGQLQEVS---KALQDTLASAGQIPFH-AEPPETIRSLQERIKS 552
++ PL +LS G+ QE + LQ+ LA AE + QE +
Sbjct: 445 LERLVKEMAPLQEELS-GKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKEL 503
Query: 553 LNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIR 612
L ++ +T ++ E + + + V+D+E Q L++ K +H + E +
Sbjct: 504 LEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDK------DHLSQQVGMLERLA 557
Query: 613 SLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQET-AYETSVKENTMKY 671
+ G ++ LV + ++++ E+ R +E + +T E S +E +
Sbjct: 558 GPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQA 617
Query: 672 METLKNKLCSCKCPLLGK--VWEADLEACRLLIQSLQLQEA--RGSL-SVEDER 720
L+ +L + ++G+ + E L+A + Q+LQ +E+ +GSL S+E E+
Sbjct: 618 NRELEKELQN----VVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQ 667
Score = 40.0 bits (92), Expect = 0.009
Identities = 66/294 (22%), Positives = 119/294 (40%), Gaps = 47/294 (15%)
Query: 456 DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQ----------GCDLT 505
D + E QL+ + L+ RM L+ ++Q+LR + +Q +QLQ + LT
Sbjct: 233 DEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVRLT 292
Query: 506 PLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVC 565
LV +L + EV++A Q+ T++ LQ ++ L L E
Sbjct: 293 CLVAELQ--KQWEVTQATQN----------------TVKELQTCLQGLELGAAEKEEDYH 334
Query: 566 MS-EKFCSTLRKKVNDIETQLPALLEAKMH--------AISGNHFWTAKDLTEEIRSLTS 616
+ + S L+ ++E +L + H A++ TA D + S
Sbjct: 335 TALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPS 394
Query: 617 E-REGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETL 675
+ + ++ L KL L K E+ NR ++ + ++ E +KE+ +E L
Sbjct: 395 DAAQEMQELGEKLQALERERTK-----VEEVNR-QQSAQLEQLVKELQLKEDARASLERL 448
Query: 676 KNKLCSCKCPLLGKVWEAD---LEACRLLIQSLQLQEARGSLSVEDERQMDDLE 726
++ + L GK EAD LL + +E L E ++Q ++ E
Sbjct: 449 VKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKE 502
Score = 38.9 bits (89), Expect = 0.020
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 31/159 (19%)
Query: 340 CLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQP 399
C L ++ +L +Q+LQ DA E ++ E L++++ L+QEK SL +L + +
Sbjct: 913 CALTVEKERVEEALACAVQELQ-DAKEAASRER-EGLERQVAGLQQEKESLQEKLKAAKA 970
Query: 400 ALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLL 459
A S G A QA R + Q+A+ + +T
Sbjct: 971 AAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTL--------------------------- 1003
Query: 460 QEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ 498
K QL EI Q+R+ + + LR ++EEQ +QLQ
Sbjct: 1004 --KFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQ 1040
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 49.7 bits (117), Expect = 1e-05
Identities = 98/512 (19%), Positives = 194/512 (37%), Gaps = 54/512 (10%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYDKAET-LQQRLEDLEQEKISLHFQLPSRQPAL 401
+ R Q E+ +L Q+ +E A D +K + LQQ L+DL + + QL S
Sbjct: 1394 KKRFQKEIENLT---QQYEEKAAAYDKLEKTKNRLQQELDDLVVD-LDNQRQLVSNLEKK 1449
Query: 402 SSFLGHLAAQVQAALRRGATQ----QASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR-- 455
L A+ + + A + +A + T R LE + + T +
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
Query: 456 ----DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ-WQGCDLTPLVGQ 510
+ L+ K + K + L+ LE + ++++ ++EE E +LQ + L V
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 511 LSL-GQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEK 569
+L GQ + +A + + E R LQ ++ L++ + ++
Sbjct: 1570 QALKGQFERDLQARDE------------QNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLL 629
L + D+E Q + ++ + AI + L +++ E E ++
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIK-----QLRKLQAQMKDFQRELEDARASRDEIF 1672
Query: 630 VLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGK 689
+ N KK S++ D +L+ ++ E A + + E E L +L S
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK-----EELAEELASSLSGRNAL 1727
Query: 690 VWEADLEACRLLIQSLQLQEARGSLSVEDER---QMDDLEGAAPPIPPRLHSEDKRKTPL 746
E R+ +L+E +G++ +R E + + + K ++
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1787
Query: 747 KVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED 806
+ LE L LH G K + A L K+ LE+Q+
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAAL-------EAKIAQLEEQVEQEAREK--- 1837
Query: 807 LIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
Q+ + L+ + L+ ++LQ++ ++ E+
Sbjct: 1838 --QAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 49.3 bits (116), Expect = 2e-05
Identities = 101/523 (19%), Positives = 212/523 (40%), Gaps = 78/523 (14%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYD-----KAETLQQRLEDL------EQEKISLH 391
R + Q+E ++ K++KL+++ + DD + + + L++R+ DL E+EK
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 392 FQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVS 451
+L ++ ++ S +++ L++ + + L R LE A D
Sbjct: 1026 TKLKNKHESMIS-------ELEVRLKK-------EEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 452 ITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
+ + + K QL K+ E LQA + +L EI ++ L+ + L G +
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAAL-------ARLDDEIAQKNNALK----KIRELEGHI 1120
Query: 512 SLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFC 571
S LQ+ L S AE + R L E +++L L++ ++
Sbjct: 1121 S---------DLQEDLDSERAARNKAEKQK--RDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 572 S------TLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLL 625
+ T+ KK D ET+ EA++ + H ++LTE++ + L+
Sbjct: 1170 AKREQEVTVLKKALDEETRSH---EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD--- 1223
Query: 626 SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLK--------- 676
L N G ++ + ++EVEH++ E V+E K + +
Sbjct: 1224 KNKQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 677 NKLCSCKCPLLGKVWEADLEACRLLIQ----SLQLQEARGSLSVEDERQMDDLEGAAPPI 732
+KL + + G + EA+ +A +L S QLQ+ + L E ++++
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 733 PPRLHSEDKRKTPLKVLEEWKTHLIP-SLHCAGGEQKEESYILSAELGEKCEDIGKKLLY 791
R +D+ ++ + + H+ ++ + ++K + + + E E+ GKK
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE----GKKRFQ 1398
Query: 792 LEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
E + T + L + +++ L +++ L ++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQ 1441
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/447 (19%), Positives = 171/447 (38%), Gaps = 59/447 (13%)
Query: 427 DDTHTPLRMEPRLLEPTAQDSLHVSITRRDW---LLQEKQQLQKEIEALQARMFVLEAKD 483
+ H+ L E LL+ Q + + L +KQ+L++ + ++AR+ E +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 484 QQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
QQL+ E ++ QQ + L QL + L+ A A I
Sbjct: 939 QQLQAERKKMAQQ-------MLDLEEQLEEEEAARQKLQLEKVTAEA-----------KI 980
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLE--AKMHAISGNHF 601
+ L++ I L + + K+ K L ++++D+ T L E + + H
Sbjct: 981 KKLEDEI----LVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYE 661
+L ++ R+ LE L KL +S +++ ++ L+ ++ +E +
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 662 TSV---------KENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARG 712
++ K N +K + L+ + + DL++ R + Q +
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDL---------QEDLDSERAARNKAEKQ--KR 1142
Query: 713 SLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESY 772
L E E +LE + KR+ + VL++ S E +++
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 773 ILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLR------RELQMVKETLQAMI 826
EL E+ E + L+ T + + DL LR +E++ K+ L+A +
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQT-LEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 827 LQLQPAKEAGEREAAASCMTAGVHEAQ 853
+LQ GER A + VH+ Q
Sbjct: 1262 QELQSKCSDGERARAE--LNDKVHKLQ 1286
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 49.7 bits (117), Expect = 1e-05
Identities = 98/512 (19%), Positives = 194/512 (37%), Gaps = 54/512 (10%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYDKAET-LQQRLEDLEQEKISLHFQLPSRQPAL 401
+ R Q E+ +L Q+ +E A D +K + LQQ L+DL + + QL S
Sbjct: 1401 KKRFQKEIENLT---QQYEEKAAAYDKLEKTKNRLQQELDDLVVD-LDNQRQLVSNLEKK 1456
Query: 402 SSFLGHLAAQVQAALRRGATQ----QASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR-- 455
L A+ + + A + +A + T R LE + + T +
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1516
Query: 456 ----DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ-WQGCDLTPLVGQ 510
+ L+ K + K + L+ LE + ++++ ++EE E +LQ + L V
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1576
Query: 511 LSL-GQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEK 569
+L GQ + +A + + E R LQ ++ L++ + ++
Sbjct: 1577 QALKGQFERDLQARDE------------QNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLL 629
L + D+E Q + ++ + AI + L +++ E E ++
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIK-----QLRKLQAQMKDFQRELEDARASRDEIF 1679
Query: 630 VLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGK 689
+ N KK S++ D +L+ ++ E A + + E E L +L S
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK-----EELAEELASSLSGRNAL 1734
Query: 690 VWEADLEACRLLIQSLQLQEARGSLSVEDER---QMDDLEGAAPPIPPRLHSEDKRKTPL 746
E R+ +L+E +G++ +R E + + + K ++
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1794
Query: 747 KVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED 806
+ LE L LH G K + A L K+ LE+Q+
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAAL-------EAKIAQLEEQVEQEAREK--- 1844
Query: 807 LIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
Q+ + L+ + L+ ++LQ++ ++ E+
Sbjct: 1845 --QAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 49.3 bits (116), Expect = 2e-05
Identities = 101/523 (19%), Positives = 212/523 (40%), Gaps = 78/523 (14%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYD-----KAETLQQRLEDL------EQEKISLH 391
R + Q+E ++ K++KL+++ + DD + + + L++R+ DL E+EK
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 392 FQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVS 451
+L ++ ++ S +++ L++ + + L R LE A D
Sbjct: 1033 TKLKNKHESMIS-------ELEVRLKK-------EEKSRQELEKLKRKLEGDASDFHEQI 1078
Query: 452 ITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
+ + + K QL K+ E LQA + +L EI ++ L+ + L G +
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAAL-------ARLDDEIAQKNNALK----KIRELEGHI 1127
Query: 512 SLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFC 571
S LQ+ L S AE + R L E +++L L++ ++
Sbjct: 1128 S---------DLQEDLDSERAARNKAEKQK--RDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 572 S------TLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLL 625
+ T+ KK D ET+ EA++ + H ++LTE++ + L+
Sbjct: 1177 AKREQEVTVLKKALDEETRSH---EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD--- 1230
Query: 626 SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLK--------- 676
L N G ++ + ++EVEH++ E V+E K + +
Sbjct: 1231 KNKQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Query: 677 NKLCSCKCPLLGKVWEADLEACRLLIQ----SLQLQEARGSLSVEDERQMDDLEGAAPPI 732
+KL + + G + EA+ +A +L S QLQ+ + L E ++++
Sbjct: 1290 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1349
Query: 733 PPRLHSEDKRKTPLKVLEEWKTHLIP-SLHCAGGEQKEESYILSAELGEKCEDIGKKLLY 791
R +D+ ++ + + H+ ++ + ++K + + + E E+ GKK
Sbjct: 1350 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE----GKKRFQ 1405
Query: 792 LEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
E + T + L + +++ L +++ L ++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQ 1448
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/447 (19%), Positives = 171/447 (38%), Gaps = 59/447 (13%)
Query: 427 DDTHTPLRMEPRLLEPTAQDSLHVSITRRDW---LLQEKQQLQKEIEALQARMFVLEAKD 483
+ H+ L E LL+ Q + + L +KQ+L++ + ++AR+ E +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 484 QQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
QQL+ E ++ QQ + L QL + L+ A A I
Sbjct: 946 QQLQAERKKMAQQ-------MLDLEEQLEEEEAARQKLQLEKVTAEA-----------KI 987
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLE--AKMHAISGNHF 601
+ L++ I L + + K+ K L ++++D+ T L E + + H
Sbjct: 988 KKLEDEI----LVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYE 661
+L ++ R+ LE L KL +S +++ ++ L+ ++ +E +
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 662 TSV---------KENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARG 712
++ K N +K + L+ + + DL++ R + Q +
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDL---------QEDLDSERAARNKAEKQ--KR 1149
Query: 713 SLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESY 772
L E E +LE + KR+ + VL++ S E +++
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 773 ILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLR------RELQMVKETLQAMI 826
EL E+ E + L+ T + + DL LR +E++ K+ L+A +
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQT-LEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 827 LQLQPAKEAGEREAAASCMTAGVHEAQ 853
+LQ GER A + VH+ Q
Sbjct: 1269 QELQSKCSDGERARAE--LNDKVHKLQ 1293
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 49.7 bits (117), Expect = 1e-05
Identities = 98/512 (19%), Positives = 194/512 (37%), Gaps = 54/512 (10%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYDKAET-LQQRLEDLEQEKISLHFQLPSRQPAL 401
+ R Q E+ +L Q+ +E A D +K + LQQ L+DL + + QL S
Sbjct: 1401 KKRFQKEIENLT---QQYEEKAAAYDKLEKTKNRLQQELDDLVVD-LDNQRQLVSNLEKK 1456
Query: 402 SSFLGHLAAQVQAALRRGATQ----QASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR-- 455
L A+ + + A + +A + T R LE + + T +
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1516
Query: 456 ----DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ-WQGCDLTPLVGQ 510
+ L+ K + K + L+ LE + ++++ ++EE E +LQ + L V
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1576
Query: 511 LSL-GQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEK 569
+L GQ + +A + + E R LQ ++ L++ + ++
Sbjct: 1577 QALKGQFERDLQARDE------------QNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLL 629
L + D+E Q + ++ + AI + L +++ E E ++
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIK-----QLRKLQAQMKDFQRELEDARASRDEIF 1679
Query: 630 VLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGK 689
+ N KK S++ D +L+ ++ E A + + E E L +L S
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK-----EELAEELASSLSGRNAL 1734
Query: 690 VWEADLEACRLLIQSLQLQEARGSLSVEDER---QMDDLEGAAPPIPPRLHSEDKRKTPL 746
E R+ +L+E +G++ +R E + + + K ++
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1794
Query: 747 KVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED 806
+ LE L LH G K + A L K+ LE+Q+
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAAL-------EAKIAQLEEQVEQEAREK--- 1844
Query: 807 LIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
Q+ + L+ + L+ ++LQ++ ++ E+
Sbjct: 1845 --QAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 49.3 bits (116), Expect = 2e-05
Identities = 101/523 (19%), Positives = 212/523 (40%), Gaps = 78/523 (14%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYD-----KAETLQQRLEDL------EQEKISLH 391
R + Q+E ++ K++KL+++ + DD + + + L++R+ DL E+EK
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 392 FQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVS 451
+L ++ ++ S +++ L++ + + L R LE A D
Sbjct: 1033 TKLKNKHESMIS-------ELEVRLKK-------EEKSRQELEKLKRKLEGDASDFHEQI 1078
Query: 452 ITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
+ + + K QL K+ E LQA + +L EI ++ L+ + L G +
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAAL-------ARLDDEIAQKNNALK----KIRELEGHI 1127
Query: 512 SLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFC 571
S LQ+ L S AE + R L E +++L L++ ++
Sbjct: 1128 S---------DLQEDLDSERAARNKAEKQK--RDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 572 S------TLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLL 625
+ T+ KK D ET+ EA++ + H ++LTE++ + L+
Sbjct: 1177 AKREQEVTVLKKALDEETRSH---EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD--- 1230
Query: 626 SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLK--------- 676
L N G ++ + ++EVEH++ E V+E K + +
Sbjct: 1231 KNKQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Query: 677 NKLCSCKCPLLGKVWEADLEACRLLIQ----SLQLQEARGSLSVEDERQMDDLEGAAPPI 732
+KL + + G + EA+ +A +L S QLQ+ + L E ++++
Sbjct: 1290 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1349
Query: 733 PPRLHSEDKRKTPLKVLEEWKTHLIP-SLHCAGGEQKEESYILSAELGEKCEDIGKKLLY 791
R +D+ ++ + + H+ ++ + ++K + + + E E+ GKK
Sbjct: 1350 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE----GKKRFQ 1405
Query: 792 LEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
E + T + L + +++ L +++ L ++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQ 1448
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/447 (19%), Positives = 171/447 (38%), Gaps = 59/447 (13%)
Query: 427 DDTHTPLRMEPRLLEPTAQDSLHVSITRRDW---LLQEKQQLQKEIEALQARMFVLEAKD 483
+ H+ L E LL+ Q + + L +KQ+L++ + ++AR+ E +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 484 QQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
QQL+ E ++ QQ + L QL + L+ A A I
Sbjct: 946 QQLQAERKKMAQQ-------MLDLEEQLEEEEAARQKLQLEKVTAEA-----------KI 987
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLE--AKMHAISGNHF 601
+ L++ I L + + K+ K L ++++D+ T L E + + H
Sbjct: 988 KKLEDEI----LVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYE 661
+L ++ R+ LE L KL +S +++ ++ L+ ++ +E +
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1100
Query: 662 TSV---------KENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARG 712
++ K N +K + L+ + + DL++ R + Q +
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDL---------QEDLDSERAARNKAEKQ--KR 1149
Query: 713 SLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESY 772
L E E +LE + KR+ + VL++ S E +++
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 773 ILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLR------RELQMVKETLQAMI 826
EL E+ E + L+ T + + DL LR +E++ K+ L+A +
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQT-LEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 827 LQLQPAKEAGEREAAASCMTAGVHEAQ 853
+LQ GER A + VH+ Q
Sbjct: 1269 QELQSKCSDGERARAE--LNDKVHKLQ 1293
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 49.7 bits (117), Expect = 1e-05
Identities = 98/512 (19%), Positives = 194/512 (37%), Gaps = 54/512 (10%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYDKAET-LQQRLEDLEQEKISLHFQLPSRQPAL 401
+ R Q E+ +L Q+ +E A D +K + LQQ L+DL + + QL S
Sbjct: 1394 KKRFQKEIENLT---QQYEEKAAAYDKLEKTKNRLQQELDDLVVD-LDNQRQLVSNLEKK 1449
Query: 402 SSFLGHLAAQVQAALRRGATQ----QASGDDTHTPLRMEPRLLEPTAQDSLHVSITRR-- 455
L A+ + + A + +A + T R LE + + T +
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
Query: 456 ----DWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQ-WQGCDLTPLVGQ 510
+ L+ K + K + L+ LE + ++++ ++EE E +LQ + L V
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 511 LSL-GQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEK 569
+L GQ + +A + + E R LQ ++ L++ + ++
Sbjct: 1570 QALKGQFERDLQARDE------------QNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 570 FCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLL 629
L + D+E Q + ++ + AI + L +++ E E ++
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIK-----QLRKLQAQMKDFQRELEDARASRDEIF 1672
Query: 630 VLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGK 689
+ N KK S++ D +L+ ++ E A + + E E L +L S
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK-----EELAEELASSLSGRNAL 1727
Query: 690 VWEADLEACRLLIQSLQLQEARGSLSVEDER---QMDDLEGAAPPIPPRLHSEDKRKTPL 746
E R+ +L+E +G++ +R E + + + K ++
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1787
Query: 747 KVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDED 806
+ LE L LH G K + A L K+ LE+Q+
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAAL-------EAKIAQLEEQVEQEAREK--- 1837
Query: 807 LIQSLRRELQMVKETLQAMILQLQPAKEAGER 838
Q+ + L+ + L+ ++LQ++ ++ E+
Sbjct: 1838 --QAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 49.3 bits (116), Expect = 2e-05
Identities = 101/523 (19%), Positives = 212/523 (40%), Gaps = 78/523 (14%)
Query: 343 RNRRQMEVISLRLKLQKLQEDAVENDDYD-----KAETLQQRLEDL------EQEKISLH 391
R + Q+E ++ K++KL+++ + DD + + + L++R+ DL E+EK
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 392 FQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVS 451
+L ++ ++ S +++ L++ + + L R LE A D
Sbjct: 1026 TKLKNKHESMIS-------ELEVRLKK-------EEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 452 ITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQL 511
+ + + K QL K+ E LQA + +L EI ++ L+ + L G +
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAAL-------ARLDDEIAQKNNALK----KIRELEGHI 1120
Query: 512 SLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFC 571
S LQ+ L S AE + R L E +++L L++ ++
Sbjct: 1121 S---------DLQEDLDSERAARNKAEKQK--RDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 572 S------TLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLL 625
+ T+ KK D ET+ EA++ + H ++LTE++ + L+
Sbjct: 1170 AKREQEVTVLKKALDEETRSH---EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD--- 1223
Query: 626 SKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLK--------- 676
L N G ++ + ++EVEH++ E V+E K + +
Sbjct: 1224 KNKQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 677 NKLCSCKCPLLGKVWEADLEACRLLIQ----SLQLQEARGSLSVEDERQMDDLEGAAPPI 732
+KL + + G + EA+ +A +L S QLQ+ + L E ++++
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 733 PPRLHSEDKRKTPLKVLEEWKTHLIP-SLHCAGGEQKEESYILSAELGEKCEDIGKKLLY 791
R +D+ ++ + + H+ ++ + ++K + + + E E+ GKK
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE----GKKRFQ 1398
Query: 792 LEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKE 834
E + T + L + +++ L +++ L ++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQ 1441
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/447 (19%), Positives = 171/447 (38%), Gaps = 59/447 (13%)
Query: 427 DDTHTPLRMEPRLLEPTAQDSLHVSITRRDW---LLQEKQQLQKEIEALQARMFVLEAKD 483
+ H+ L E LL+ Q + + L +KQ+L++ + ++AR+ E +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 484 QQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETI 543
QQL+ E ++ QQ + L QL + L+ A A I
Sbjct: 939 QQLQAERKKMAQQ-------MLDLEEQLEEEEAARQKLQLEKVTAEA-----------KI 980
Query: 544 RSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLE--AKMHAISGNHF 601
+ L++ I L + + K+ K L ++++D+ T L E + + H
Sbjct: 981 KKLEDEI----LVMDDQNNKLSKERKL---LEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 602 WTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYE 661
+L ++ R+ LE L KL +S +++ ++ L+ ++ +E +
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093
Query: 662 TSV---------KENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARG 712
++ K N +K + L+ + + DL++ R + Q +
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDL---------QEDLDSERAARNKAEKQ--KR 1142
Query: 713 SLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESY 772
L E E +LE + KR+ + VL++ S E +++
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 773 ILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLR------RELQMVKETLQAMI 826
EL E+ E + L+ T + + DL LR +E++ K+ L+A +
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQT-LEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 827 LQLQPAKEAGEREAAASCMTAGVHEAQ 853
+LQ GER A + VH+ Q
Sbjct: 1262 QELQSKCSDGERARAE--LNDKVHKLQ 1286
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 49.3 bits (116), Expect = 2e-05
Identities = 111/543 (20%), Positives = 210/543 (38%), Gaps = 71/543 (13%)
Query: 345 RRQMEVISLRLKLQKLQEDAVENDDY--DKAETLQQRLEDLEQEKISLHFQLPSRQPALS 402
R+Q + LR Q E++V D A+T+Q + +++E+ K QL ++
Sbjct: 1443 RKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLK-----QLIDKETNDR 1497
Query: 403 SFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVS---------IT 453
L A++Q +S +T L+++ + L D VS IT
Sbjct: 1498 KCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDIT 1557
Query: 454 RRDWLLQE----KQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVG 509
R L+E KQ++++E+ L+ K ++L E+E + L+ Q +T L
Sbjct: 1558 RFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQ 1617
Query: 510 QLSLGQLQEVSKALQDTLASA-----GQIPFHAEPPETIRSLQERIKSLNLSLKEITTKV 564
QL Q V K +D L G + E +R L +++L L + V
Sbjct: 1618 QLE--QASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESV 1675
Query: 565 CMSEKFCSTLRKKVNDIETQL--PALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLE 622
+ +K + D L + ++ +++ N L EE+R+L E + L
Sbjct: 1676 KQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR 1735
Query: 623 ---------------GLLSKLLVLSSRNVKKLGSVKE---DYNRLRREVE-HQETAYETS 663
L S+L + ++R ++ G + + + LR+E+E Q+ A E S
Sbjct: 1736 RGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEAS 1795
Query: 664 VKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMD 723
N ++ + ++ + LL K+ + + RL +L A+ +L E
Sbjct: 1796 ---NRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETR---- 1848
Query: 724 DLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAG--GEQKEESYILSAELGEK 781
+ RL E ++ L +WKT ++E+S L +
Sbjct: 1849 --------VKQRLECE--KQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSE 1898
Query: 782 CEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAA 841
E + ++ +E++ + ED + + +L+ + Q I +L+ RE
Sbjct: 1899 IERLQAEIKRIEERCRRKL----EDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQ 1954
Query: 842 ASC 844
C
Sbjct: 1955 TEC 1957
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,167,470
Number of Sequences: 37866
Number of extensions: 1837927
Number of successful extensions: 10846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 568
Number of HSP's that attempted gapping in prelim test: 8951
Number of HSP's gapped (non-prelim): 1943
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.