Guide to the Human Genome
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Search of human proteins with 13540594

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13540594 lectin, mannose-binding 2-like isoform 2 [Homo
sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13540594 lectin, mannose-binding 2-like isoform 2 [Homo sapiens]   721   0.0  
gi|214010240 lectin, mannose-binding 2-like isoform 1 [Homo sapi...   712   0.0  
gi|5803023 lectin, mannose-binding 2 precursor [Homo sapiens]         387   e-107
gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]        154   1e-37
gi|75677363 lectin, mannose-binding, 1 like [Homo sapiens]            116   3e-26
gi|150378498 fragile site-associated protein [Homo sapiens]            33   0.38 
gi|23111026 sorting nexin 11 [Homo sapiens]                            30   3.2  
gi|23111028 sorting nexin 11 [Homo sapiens]                            30   3.2  
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...    30   4.2  
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...    30   4.2  
gi|4585643 zinc finger protein 264 [Homo sapiens]                      30   4.2  
gi|116686120 periaxin isoform 2 [Homo sapiens]                         29   7.1  
gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]           29   7.1  
gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens]           29   7.1  
gi|209413732 poliovirus receptor isoform delta [Homo sapiens]          28   9.3  
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]          28   9.3  

>gi|13540594 lectin, mannose-binding 2-like isoform 2 [Homo sapiens]
          Length = 348

 Score =  721 bits (1860), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP 60
           MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP
Sbjct: 1   MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP 60

Query: 61  YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ 120
           YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ
Sbjct: 61  YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ 120

Query: 121 GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVN 180
           GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVN
Sbjct: 121 GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVN 180

Query: 181 NGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEV 240
           NGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEV
Sbjct: 181 NGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEV 240

Query: 241 PGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLP 300
           PGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLP
Sbjct: 241 PGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLP 300

Query: 301 EMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 348
           EMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY
Sbjct: 301 EMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 348


>gi|214010240 lectin, mannose-binding 2-like isoform 1 [Homo
           sapiens]
          Length = 359

 Score =  712 bits (1838), Expect = 0.0
 Identities = 348/359 (96%), Positives = 348/359 (96%), Gaps = 11/359 (3%)

Query: 1   MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP 60
           MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP
Sbjct: 1   MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKP 60

Query: 61  YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ 120
           YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ
Sbjct: 61  YQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQ 120

Query: 121 GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQE----------- 169
           GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQE           
Sbjct: 121 GKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQEAQKRRYSPGVQ 180

Query: 170 RVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDID 229
           RVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDID
Sbjct: 181 RVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDID 240

Query: 230 GKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDV 289
           GKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDV
Sbjct: 241 GKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDV 300

Query: 290 FLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 348
           FLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY
Sbjct: 301 FLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 359


>gi|5803023 lectin, mannose-binding 2 precursor [Homo sapiens]
          Length = 356

 Score =  387 bits (993), Expect = e-107
 Identities = 195/361 (54%), Positives = 252/361 (69%), Gaps = 21/361 (5%)

Query: 3   ATLGPLGSWQQWRRCLSARDG--------SRMLLLLLLLGSGQGPQQVGAGQTFEYLKRE 54
           A  G +  W   RRCL  R G        +  L LLLLLGS       G     E+LKRE
Sbjct: 2   AAEGWIWRWGWGRRCLG-RPGLLGPGPGPTTPLFLLLLLGSVTADITDGNS---EHLKRE 57

Query: 55  HSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVH 114
           HSL KPYQGVG+ S  LW+  G+ M+ +QY+RLTPD +SK+G++WN  PCFL+DWE+ VH
Sbjct: 58  HSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVH 117

Query: 115 FKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPY 174
           FK+HG GKKNLHGDG+A+WYT+DR+ PGPVFG+ D F GL +F+DTYPN+E   ERVFPY
Sbjct: 118 FKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDE-TTERVFPY 176

Query: 175 ISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEW 234
           IS MVNNGSLSYDH +DGR TEL GCTA  RN  +DTFL +RY +  LT+M D++ K+EW
Sbjct: 177 ISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEW 236

Query: 235 RDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSV 294
           ++CI++ GVRLP GYYFG S+ TGDLSDNHD+IS+KLF+L VE TP+EE +      PSV
Sbjct: 237 KNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSV 296

Query: 295 DNMKLPEMTAPLP-------PLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRF 347
           + +K P+     P       PL+G  +FL++  +L+  V   V+G +++ K QE++ KRF
Sbjct: 297 NFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERN-KRF 355

Query: 348 Y 348
           Y
Sbjct: 356 Y 356


>gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]
          Length = 510

 Score =  154 bits (389), Expect = 1e-37
 Identities = 90/271 (33%), Positives = 144/271 (53%), Gaps = 18/271 (6%)

Query: 15  RRCLSARDGSRMLLLLLLLGS-------GQGPQQVGAGQTFEYLKREHSLSKPYQGVGTG 67
           +R L AR       LLL LG        G  P      + FEY   ++S   P+     G
Sbjct: 6   QRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEY---KYSFKGPHLVQSDG 62

Query: 68  SSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHG 127
           +   W   GNA+  +  IR+ P ++S++G++W +      +WE++V F++ G+G+  +  
Sbjct: 63  TVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGR--IGA 120

Query: 128 DGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYD 187
           DGLAIWY +++   GPVFG+ D + G+G+F D++ N+ K+     P I  + NNG + YD
Sbjct: 121 DGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNN---PAIVIIGNNGQIHYD 177

Query: 188 HERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMD---IDGKHEWRDCIEVPGVR 244
           H+ DG    L  C    RN  Y     I Y +  LT+M++      K+++  C +V  + 
Sbjct: 178 HQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMI 237

Query: 245 LPRGYYFGTSSITGDLSDNHDVISLKLFELT 275
           +P   +FG S+ TG L+D+HDV+S   F+LT
Sbjct: 238 IPAQGHFGISAATGGLADDHDVLSFLTFQLT 268



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 7/59 (11%)

Query: 291 LPSVDNMKLPEMTAPLPPL-SGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY 348
           +PS +  K PE    LPP  S L+    + F +V +V  + IG I+Y   QE + K+F+
Sbjct: 458 MPSNEKPKCPE----LPPFPSCLSTVHFIIFVVVQTV--LFIGYIMYRSQQEAAAKKFF 510


>gi|75677363 lectin, mannose-binding, 1 like [Homo sapiens]
          Length = 526

 Score =  116 bits (290), Expect = 3e-26
 Identities = 78/261 (29%), Positives = 128/261 (49%), Gaps = 12/261 (4%)

Query: 23  GSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMT 82
           G    LLLLLL            + FEY   + S   P   +       W+  G+A++  
Sbjct: 8   GPLFCLLLLLLDPHSPETGCPPLRRFEY---KLSFKGPRLALPGAGIPFWSHHGDAILGL 64

Query: 83  QYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPG 142
           + +RLTP M+++ GA+W+R       WE++V  ++ G G++     G+A+WYT+ R   G
Sbjct: 65  EEVRLTPSMRNRSGAVWSRASVPFSAWEVEVQMRVTGLGRRG--AQGMAVWYTRGRGHVG 122

Query: 143 PVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYDHERDGRPTELGGCTA 202
            V G +  + G+G+F D+ P E+ Q     P I  + ++G +  +   DG    LG C  
Sbjct: 123 SVLGGLASWDGIGIFFDS-PAEDTQDS---PAIRVLASDGHIPSEQPGDGASQGLGSCHW 178

Query: 203 IVRNLHYDTFLVIRYVKRHLTIMMD--IDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDL 260
             RN  +     I Y  + L + ++  +        C++V  + L  G +FG S+ TG L
Sbjct: 179 DFRNRPHPFRARITYWGQRLRMSLNSGLTPSDPGEFCVDVGPLLLVPGGFFGVSAATGTL 238

Query: 261 SDNHDVISLKLFELTVERTPE 281
           +D+HDV+S   F L+ E +PE
Sbjct: 239 ADDHDVLSFLTFSLS-EPSPE 258


>gi|150378498 fragile site-associated protein [Homo sapiens]
          Length = 5005

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 13/79 (16%)

Query: 45  GQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPC 104
           G+   Y+  E  +S P   + T SSS W  +G          +  D +  +G+  +  P 
Sbjct: 754 GEDDMYMDFEEVISSPVLSLSTSSSSGWTAVG----------MENDKKENEGSAKSIHPL 803

Query: 105 FLRDWELQV---HFKIHGQ 120
            LR W++ V    +K+HG+
Sbjct: 804 ALRPWDITVLVNLYKVHGR 822


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 16/32 (50%), Positives = 23/32 (71%), Gaps = 2/32 (6%)

Query: 280 PEEEKLHRDVFLPSVDNMKLPEMTAP-LPPLS 310
           P EEK H +V+ P VD+ ++P + +P LPPLS
Sbjct: 197 PSEEKDHLEVWAPVVDS-EVPSLESPTLPPLS 227


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 16/32 (50%), Positives = 23/32 (71%), Gaps = 2/32 (6%)

Query: 280 PEEEKLHRDVFLPSVDNMKLPEMTAP-LPPLS 310
           P EEK H +V+ P VD+ ++P + +P LPPLS
Sbjct: 197 PSEEKDHLEVWAPVVDS-EVPSLESPTLPPLS 227


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 5/56 (8%)

Query: 39  PQQVGAGQ---TFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDM 91
           P   GAG+   TF+   R H L  PYQG  T    L   MG+ + +  Y  LT D+
Sbjct: 267 PMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDY--LTTDL 320


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 5/56 (8%)

Query: 39  PQQVGAGQ---TFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDM 91
           P   GAG+   TF+   R H L  PYQG  T    L   MG+ + +  Y  LT D+
Sbjct: 267 PMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDY--LTTDL 320


>gi|4585643 zinc finger protein 264 [Homo sapiens]
          Length = 627

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 9/77 (11%)

Query: 15  RRCLSARDGSRMLLLLLLLGSGQGPQQ-VGAGQTFEYL------KREHSLSKPYQGVGTG 67
           + C  A    + L+    + +G+ P + V  G+ F  +      KR HS  KPY+ V  G
Sbjct: 458 KECGKAFSNRKDLIRHFSIHTGEKPYECVECGKAFTRMSGLTRHKRIHSGEKPYECVECG 517

Query: 68  SSSLW--NLMGNAMVMT 82
            S  W  NL+ +A++ T
Sbjct: 518 KSFCWSTNLIRHAIIHT 534


>gi|116686120 periaxin isoform 2 [Homo sapiens]
          Length = 1461

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 240 VPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKL 299
           VP VRLP       S +         V  ++L E+ + + PE +    ++ LP V  MKL
Sbjct: 538 VPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKV--PEMKLPKVPEMKL 595

Query: 300 PEMTAP---LPPLSGLAL 314
           PEM  P   LP +  +A+
Sbjct: 596 PEMKLPEVQLPKVPEMAV 613


>gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]
          Length = 450

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 279 TPEEEKLHRDVFLPSVDNMKLPEM---TAPLPPLSGLALFLIVFFSLVF 324
           T  +++ H  V + SV   KL +     +PL  ++G++LFLI+   L+F
Sbjct: 310 TGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLF 358


>gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens]
          Length = 462

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 279 TPEEEKLHRDVFLPSVDNMKLPEM---TAPLPPLSGLALFLIVFFSLVF 324
           T  +++ H  V + SV   KL +     +PL  ++G++LFLI+   L+F
Sbjct: 322 TGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLF 370


>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
          Length = 392

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/36 (38%), Positives = 22/36 (61%)

Query: 310 SGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRK 345
           SG++   I+F  L   VF I++GI +Y  W + SR+
Sbjct: 338 SGISRNAIIFLVLGILVFLILLGIGIYFYWSKCSRE 373


>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
          Length = 417

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 14/36 (38%), Positives = 22/36 (61%)

Query: 310 SGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRK 345
           SG++   I+F  L   VF I++GI +Y  W + SR+
Sbjct: 338 SGISRNAIIFLVLGILVFLILLGIGIYFYWSKCSRE 373


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,671,583
Number of Sequences: 37866
Number of extensions: 685431
Number of successful extensions: 1384
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1357
Number of HSP's gapped (non-prelim): 28
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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