Search of human proteins with 13435391

Search of human proteins with 13435391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide
2 [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ...  1079   0.0  
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11...   951   0.0  
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11...   951   0.0  
gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide...   942   0.0  
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide...   893   0.0  
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8...   891   0.0  
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide...   703   0.0  
gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide...   423   e-118
gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide...   418   e-117
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ...   416   e-116
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide...   415   e-116
gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide ...   402   e-112
gi|30023836 cytochrome P450 4Z1 [Homo sapiens]                        387   e-107
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide...   293   3e-79
gi|239757171 PREDICTED: similar to cytochrome P450, family 4, su...   267   2e-71
gi|239751683 PREDICTED: similar to cytochrome P450, family 4, su...   267   2e-71
gi|239746187 PREDICTED: similar to cytochrome P450, family 4, su...   267   2e-71
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7...   150   3e-36
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ...   145   7e-35
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ...   142   1e-33
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ...   141   1e-33
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...   139   6e-33
gi|5729796 cytochrome P450, family 46 [Homo sapiens]                  134   3e-31
gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide ...   111   2e-24
gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [H...   110   2e-24
gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [H...   110   2e-24
gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide ...   109   5e-24
gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide ...   102   6e-22
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ...   102   8e-22
gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1 ...   100   2e-21

>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
           [Homo sapiens]
          Length = 520

 Score = 1079 bits (2791), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF
Sbjct: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
           WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK
Sbjct: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
Sbjct: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL
Sbjct: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
Sbjct: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC
Sbjct: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
Sbjct: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520


>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score =  951 bits (2459), Expect = 0.0
 Identities = 452/519 (87%), Positives = 480/519 (92%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           M QLSLSWLGL PVAASPWLLLLLVG SWLLA VLAWTY FYDNCRRL+CFPQPP++NWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
           WGHQG+V PTEEGM+ LTQLV TYPQGFK+W+GP  PLL LCHPDIIR + +ASAA+APK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D  FY FL+PWLGDGLLLS GDKWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LASEGSA LDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+ +IL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           LH DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDREP EIEWDDLA LPFLTMC+KESLRLHPPVPVISR  TQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD ENIKERSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VLALTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519


>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score =  951 bits (2459), Expect = 0.0
 Identities = 452/519 (87%), Positives = 480/519 (92%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           M QLSLSWLGL PVAASPWLLLLLVG SWLLA VLAWTY FYDNCRRL+CFPQPP++NWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
           WGHQG+V PTEEGM+ LTQLV TYPQGFK+W+GP  PLL LCHPDIIR + +ASAA+APK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D  FY FL+PWLGDGLLLS GDKWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LASEGSA LDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+ +IL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           LH DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDREP EIEWDDLA LPFLTMC+KESLRLHPPVPVISR  TQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD ENIKERSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VLALTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519


>gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide 3
           [Homo sapiens]
          Length = 520

 Score =  942 bits (2435), Expect = 0.0
 Identities = 456/520 (87%), Positives = 479/520 (92%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           M QLSLS LGLWP+AASPWLLLLLVGASWLLA +LAWTY FYDNC RLRCFPQPP+RNWF
Sbjct: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
            GH G+++ +EEG+     L  T+      W+GP   ++ + HP  I+ V+ A AAI PK
Sbjct: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           DK FYSFL+PWLGDGLLLSAG+KWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
Sbjct: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LASEGSA LDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALV+KRH +IL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           L+IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
Sbjct: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLA LPFLTMC+KESLRLHPPVP +SR  TQDIVLPDGRVIPKGIIC
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           LISVFGTHHNPAVWPDPEVYDPFRFDP+NIKERSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VL LTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
Sbjct: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520


>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
           [Homo sapiens]
          Length = 524

 Score =  893 bits (2308), Expect = 0.0
 Identities = 425/520 (81%), Positives = 460/520 (88%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           MS LSL WLGL PVA SPWLLLLLV  SWLLA +LAWTYAFY+NCRRL+CFPQPP+RNWF
Sbjct: 1   MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
           WGH G++ PTEEG++  TQ+ ATY QGF VW+GPI P + LCHPD IRS+ NASAAIAPK
Sbjct: 61  WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D  F  FL+PWLG+G+LLS GDKWSRHRRMLTPAFHFNILK Y+ IFN+S NIM  KWQ 
Sbjct: 121 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LASEGS+ LDMFEHISLMTLDSLQKC+FSFDSHCQE+PSEYIA ILELSALV KR   IL
Sbjct: 181 LASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
            H+DFLYYL+ DG+RF RACRLVHDFTDAVI+ERRRTLP+QG+DDF + KAKSKTLDFID
Sbjct: 241 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK LSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDR+PKEIEWDDLA LPFLTMC+KESLRLHPP P ISR  TQDIVLPDGRVIPKGI C
Sbjct: 361 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           LI + G HHNP VWPDPEVYDPFRFDPEN K RSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VLAL LL FR LPDHTEPRRK EL++RAEGGLWLRVEPL+
Sbjct: 481 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520


>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
           [Homo sapiens]
          Length = 520

 Score =  891 bits (2303), Expect = 0.0
 Identities = 422/519 (81%), Positives = 468/519 (90%)

Query: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60
           MS LSLSWLGL PVAASPWLLLL+VGASWLLA +LAWTYAFY N RRLRCFPQP ++NWF
Sbjct: 1   MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWF 60

Query: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120
            GH G+V PTEEG+RVLTQLVATYPQGF  W+GPI+P+++LCHPDI+RSVIN S AI  K
Sbjct: 61  LGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDK 120

Query: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D  FY  L+PWLGDGLLLS GDKW  HRR+LTPAFHFNILKPY+KIF++S NIMHAKWQ 
Sbjct: 121 DIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQR 180

Query: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240
           LA EGS CLD+FEHISLMTLDSLQKC+FSFDS+CQEKPSEYI AI+ELSALV KR+++  
Sbjct: 181 LAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFF 240

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
            + DFLY+LTP G+RF RACRLVHDFTDAVIQERRRTL SQGVDDFLQAKAKSKTLDFID
Sbjct: 241 RYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLS+D++GK+LSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQERCRQEVQE
Sbjct: 301 VLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLA LPFLTMC+KESLRLHPP+P  +R  TQD+VLPD RVIPKG +C
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
            I++F  HHNP+VWPDPEVYDPFRFDPEN ++RSP+AFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 NINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKV 480

Query: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VLALTLLRFR+LPDH EPRR PE+VLRAE GLWLRVEPL
Sbjct: 481 VLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVEPL 519


>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
           [Homo sapiens]
          Length = 531

 Score =  703 bits (1814), Expect = 0.0
 Identities = 335/506 (66%), Positives = 413/506 (81%), Gaps = 2/506 (0%)

Query: 15  AASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNPTEEGM 74
           A S  LL LL     LL   L    +FY  CRRLRCFPQPPRRNW  GH GM  P E G+
Sbjct: 23  AVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPNEAGL 82

Query: 75  RVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGD 134
           +   +++        VWMGP+ PLL L HPD I+ ++ ASAAIAPKD  FY FL+PWLGD
Sbjct: 83  QDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGD 142

Query: 135 GLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEH 194
           GLLLS GDKWSRHRR+LTPAFHF+ILKPYMKIFN+S +IMHAKW+ LA   +  LDMFEH
Sbjct: 143 GLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEH 202

Query: 195 ISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQ 254
           ISLMTLDSLQKCVFS++S+CQEK S+YI+AI+ELSAL  +R + +  ++DF+YY + DG+
Sbjct: 203 ISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGR 262

Query: 255 RFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLS 314
           RFR+AC +VH FT  VIQERRR L  QG + +L+AK + KTLDFIDVLLL++DEDGK+LS
Sbjct: 263 RFRQACDMVHHFTTEVIQERRRALRQQGAEAWLKAK-QGKTLDFIDVLLLARDEDGKELS 321

Query: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
           DEDIRAEADTFMFEGHDTT+SG+SW+L++LAK+PEYQE+CR+E+QE++K RE +E+EWDD
Sbjct: 322 DEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDD 381

Query: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW 434
           L  LPF TMC+KESLR +PPV ++SR  T+DI LPDGR+IPKGIICL+S++GTHHNP VW
Sbjct: 382 LTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW 441

Query: 435 PDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPD 494
           PD +VY+P+RFDP+N ++RSPLA++PFSAGPRNCIGQ+FAMAE++VV+ALTLLRFR+  D
Sbjct: 442 PDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVD 501

Query: 495 HT-EPRRKPELVLRAEGGLWLRVEPL 519
            T + RRKPEL+LR E GLWL+VEPL
Sbjct: 502 RTRKVRRKPELILRTENGLWLKVEPL 527


>gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide 11
           [Homo sapiens]
          Length = 519

 Score =  423 bits (1088), Expect = e-118
 Identities = 235/513 (45%), Positives = 318/513 (61%), Gaps = 23/513 (4%)

Query: 10  GLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNP 69
           G+   A+   LLLLL+ A  L  H   W        + L+ FP PP  +W +GH   +  
Sbjct: 17  GILQAASLLILLLLLIKAVQLYLH-RQWLL------KALQQFPCPPS-HWLFGHIQELQQ 68

Query: 70  TEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLE 129
            +E  R+  + V T+P     W+      + L  PD ++ ++  S    PK    Y FL 
Sbjct: 69  DQELQRI-QKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSD---PKSHGSYRFLA 124

Query: 130 PWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACL 189
           PW+G GLLL  G  W +HRRMLTPAFH++ILKPY+ +  +SV +M  KW+ L  + S  L
Sbjct: 125 PWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSP-L 183

Query: 190 DMFEHISLMTLDSLQKCVFSFDSHCQ--EKPSEYIAAILELSALVSKRHHEILLHIDFLY 247
           ++F+H+SLMTLD++ KC FS     Q       YI AI +L+ LV  R        D +Y
Sbjct: 184 EVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIY 243

Query: 248 YLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD 307
            LT  G+   RAC+L H  TD VIQ R+  L  +G    L+   + + LDF+D+LLL+K 
Sbjct: 244 SLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGE---LEKIKRKRHLDFLDILLLAKM 300

Query: 308 EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREP 367
           E+G  LSD+D+RAE DTFMFEGHDTTASG+SW+LY LA HP++QERCR+E+  LL D   
Sbjct: 301 ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA- 359

Query: 368 KEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGT 427
             I W+ L  +P+ TMC+KE+LRL+PPVP I R ++  +  PDGR +PKGI+ L+S++G 
Sbjct: 360 -SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGL 418

Query: 428 HHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLL 487
           HHNP VWP+PEV+DPFRF P + +     AF+PFS G RNCIG+ FAM E+KV  ALTLL
Sbjct: 419 HHNPKVWPNPEVFDPFRFAPGSAQHSH--AFLPFSGGSRNCIGKQFAMNELKVATALTLL 476

Query: 488 RFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
           RF +LPD T  P     LVL+++ G+ LR+  L
Sbjct: 477 RFELLPDPTRIPIPIARLVLKSKNGIHLRLRRL 509


>gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform b [Homo sapiens]
          Length = 511

 Score =  418 bits (1075), Expect = e-117
 Identities = 225/518 (43%), Positives = 317/518 (61%), Gaps = 22/518 (4%)

Query: 4   LSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGH 63
           LS S LGLW         L+LV     L H+L          + +  FP PP  +W +GH
Sbjct: 8   LSFSSLGLWASG------LILVLGFLKLIHLLLRRQTL---AKAMDKFPGPPT-HWLFGH 57

Query: 64  QGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKF 123
              +  T    +V++     +P    +W G     L++  PD  ++V +     AP    
Sbjct: 58  ALEIQETGSLDKVVSW-AHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPD--- 113

Query: 124 FYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
            Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F ES  IM  KW+  A 
Sbjct: 114 VYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAR 173

Query: 184 EGSACLDMFEHISLMTLDSLQKCVFSF-DSHCQEKPSEYIAAILELSALVSKRHHEILLH 242
           EG +  D+F  +  M L++L KC F   D+    + S Y  A+ +L+ L+ +R      H
Sbjct: 174 EGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYH 232

Query: 243 IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
            DF+Y+LTP G+RF RAC++ HD TD VI+ER+  L  + V   +Q +   + LDF+D+L
Sbjct: 233 NDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLDIL 289

Query: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
           L ++DED  KLSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q RCR+EV+E+L
Sbjct: 290 LGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREIL 349

Query: 363 KDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLI 422
            D++    +WDDL  + +LTMC+KES RL+PPVP + R +++ +   DGR +P G +  +
Sbjct: 350 GDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISM 407

Query: 423 SVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVL 482
            ++  H N AVWPDPEV+D  RF  EN  +R P AF+PFSAGPRNCIGQ FAM+EMKVV 
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467

Query: 483 ALTLLRFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
           A+ LLRF    D +  P + P+LVLR++ G  L ++PL
Sbjct: 468 AMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505


>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
           [Homo sapiens]
          Length = 509

 Score =  416 bits (1070), Expect = e-116
 Identities = 204/478 (42%), Positives = 302/478 (63%), Gaps = 14/478 (2%)

Query: 46  RRLRCFPQPPRRNWFWGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPD 105
           R LR FP PP  +WF GHQ  +   ++ M  L +++  YP+ F  W+GP      +  PD
Sbjct: 41  RDLRPFPAPPT-HWFLGHQKFIQ--DDNMEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPD 97

Query: 106 IIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMK 165
             +++++ +    PK ++   F  P LG GL    G KW +HRR+LTP FHFNILK Y++
Sbjct: 98  YAKTLLSRTD---PKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIE 154

Query: 166 IFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSE--YIA 223
           +   SV +M  KW+ + S     ++++EHI+ M+LD + KC FS +++CQ   +   Y  
Sbjct: 155 VMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAK 214

Query: 224 AILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGV 283
           AI ELS ++  R + +L H D ++ L+P G RF++  R+++ +TD +IQER+++L +   
Sbjct: 215 AIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVK 274

Query: 284 DDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYH 343
            D      K K  DF+D++L +KDE G   SD D+ +E  TF+  GHDT A+ +SW+LY 
Sbjct: 275 QD---NTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYC 331

Query: 344 LAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVT 403
           LA +PE+QERCR+EV+ +L D     I WD L  + + TMC+KE+ RL P VP ISR ++
Sbjct: 332 LALNPEHQERCREEVRGILGDGS--SITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389

Query: 404 QDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSA 463
           + +  PDG  +P GI  ++S++G HHNPAVW +P+V+DP RF  EN  +R P A++PFSA
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449

Query: 464 GPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKP-ELVLRAEGGLWLRVEPLS 520
           G RNCIGQ FAM E+KV +AL LL FRV PD T P   P   +L+ + G++L ++ LS
Sbjct: 450 GSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKLS 507


>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform a [Homo sapiens]
          Length = 512

 Score =  415 bits (1066), Expect = e-116
 Identities = 224/519 (43%), Positives = 315/519 (60%), Gaps = 23/519 (4%)

Query: 4   LSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGH 63
           LS S LGLW         L+LV     L H+L          + +  FP PP  +W +GH
Sbjct: 8   LSFSSLGLWASG------LILVLGFLKLIHLLLRRQTL---AKAMDKFPGPPT-HWLFGH 57

Query: 64  QGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKF 123
              +  T    +V++     +P    +W G     L++  PD  ++V +     AP    
Sbjct: 58  ALEIQETGSLDKVVSW-AHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPD--- 113

Query: 124 FYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLAS 183
            Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F ES  IM  KW+  A 
Sbjct: 114 VYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAR 173

Query: 184 EGSACLDMFEHISLMTLDSLQKCVFSFDSHC--QEKPSEYIAAILELSALVSKRHHEILL 241
           EG +  D+F  +  M L++L KC F          + S Y  A+ +L+ L+ +R      
Sbjct: 174 EGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQY 232

Query: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
           H DF+Y+LTP G+RF RAC++ HD TD VI+ER+  L  + V   +Q +   + LDF+D+
Sbjct: 233 HNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLDI 289

Query: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
           LL ++DED  KLSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q RCR+EV+E+
Sbjct: 290 LLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREI 349

Query: 362 LKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICL 421
           L D++    +WDDL  + +LTMC+KES RL+PPVP + R +++ +   DGR +P G +  
Sbjct: 350 LGDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLIS 407

Query: 422 ISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVV 481
           + ++  H N AVWPDPEV+D  RF  EN  +R P AF+PFSAGPRNCIGQ FAM+EMKVV
Sbjct: 408 MHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 467

Query: 482 LALTLLRFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
            A+ LLRF    D +  P + P+LVLR++ G  L ++PL
Sbjct: 468 TAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 506


>gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide 22
           [Homo sapiens]
          Length = 519

 Score =  402 bits (1032), Expect = e-112
 Identities = 229/513 (44%), Positives = 313/513 (61%), Gaps = 23/513 (4%)

Query: 10  GLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNP 69
           G+  V +   LLLLL+ A+ L  H   W        + L+ FP PP  +W +GH      
Sbjct: 17  GILQVTSLLILLLLLIKAAQLYLH-RQWLL------KALQQFPCPPS-HWLFGHIQEFQH 68

Query: 70  TEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLE 129
            +E  R+  + V T+P     W+      + L  PD ++ ++  S    PK    Y FL 
Sbjct: 69  DQELQRI-QERVKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSD---PKSHGSYKFLA 124

Query: 130 PWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACL 189
           P +G GLLL  G  W +HRRMLTPAFH +ILKPY+ +  +SV +M  KW+ L  + S  L
Sbjct: 125 PRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSP-L 183

Query: 190 DMFEHISLMTLDSLQKCVFSFDSHCQ--EKPSEYIAAILELSALVSKRHHEILLHIDFLY 247
           ++F+H+SLMTLD++ K  FS     Q       YI AI +L++LV           D +Y
Sbjct: 184 EVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIY 243

Query: 248 YLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD 307
            LT  G+   RAC+L H  TD VIQ R+  L  +G    L+   + + LDF+D+LLL+K 
Sbjct: 244 SLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGE---LEKIKRKRHLDFLDILLLAKM 300

Query: 308 EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREP 367
           E+G  LSD+D+RAE DTFMFEGHDTTASG+SW+LY LA HP++QERCR+E+  LL D   
Sbjct: 301 ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGD--G 358

Query: 368 KEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGT 427
             I W+ L  +P+ TMC+KE+LRL+PPVP I R ++  +  PDGR +PKGI+ L+S++G 
Sbjct: 359 ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGL 418

Query: 428 HHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLL 487
           HHNP VWP+ EV+DP RF P + +     AF+PFS G RNCIG+ FAM ++KV  ALTLL
Sbjct: 419 HHNPKVWPNLEVFDPSRFAPGSAQHSH--AFLPFSGGSRNCIGKQFAMNQLKVARALTLL 476

Query: 488 RFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
           RF +LPD T  P     LVL+++ G+ LR+  L
Sbjct: 477 RFELLPDPTRIPIPMARLVLKSKNGIHLRLRRL 509


>gi|30023836 cytochrome P450 4Z1 [Homo sapiens]
          Length = 505

 Score =  387 bits (995), Expect = e-107
 Identities = 209/509 (41%), Positives = 312/509 (61%), Gaps = 18/509 (3%)

Query: 7   SWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGM 66
           SWL    + A P+LLL+L+  S LL  V+          R L  FP PP  +WF+GH+  
Sbjct: 4   SWLQ--ELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPA-HWFYGHKEF 60

Query: 67  VNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYS 126
             P +E   V  +L+  YP    +W+GP +   S+  PD  + ++       PK    + 
Sbjct: 61  Y-PVKE-FEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQD---PKSAVSHK 115

Query: 127 FLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGS 186
            LE W+G GL+   G KW +HR+++ P F+ +ILK ++ + +ESV +M  KW+   ++ S
Sbjct: 116 ILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNS 175

Query: 187 ACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPS--EYIAAILELSALVSKRHHEILLHID 244
             L++F+H+SLMTLDS+ KC FS     Q   +   Y+ A+  LS + ++R +  L H D
Sbjct: 176 R-LELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHND 234

Query: 245 FLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLL 304
            ++  +  GQ F +  + +H FT+ VIQ+R+ +L     D   Q   + +  DF+D+LL 
Sbjct: 235 LVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLK----DKLKQDTTQKRRWDFLDILLS 290

Query: 305 SKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKD 364
           +K E+ K  S+ D++AE  TFMF GHDTT+S +SW+LY LAK+PE+Q+RCR E++ELL D
Sbjct: 291 AKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGD 350

Query: 365 REPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISV 424
                I W+ L+ +P+ TMC+KE LRL+ PV  ISR + + I  PDGR +P GI   I++
Sbjct: 351 GS--SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINI 408

Query: 425 FGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLAL 484
           +  HHNP  W DP+V++P RF  EN ++  P AFIPFSAG RNCIGQ FA+ E KV +AL
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468

Query: 485 TLLRFRVLPDHTEPRRK-PELVLRAEGGL 512
           TLLRF++ PDH+ P +   ++VL+++ G+
Sbjct: 469 TLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497


>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
           [Homo sapiens]
          Length = 525

 Score =  293 bits (750), Expect = 3e-79
 Identities = 184/529 (34%), Positives = 296/529 (55%), Gaps = 31/529 (5%)

Query: 4   LSLSW--LGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFW 61
           L L W  L LW  A++    L L GAS +L+ +L    ++    +++R  P   R     
Sbjct: 6   LGLVWQKLLLWGAASA----LSLAGASLVLS-LLQRVASYARKWQQMRPIPTVARAYPLV 60

Query: 62  GHQGMVNPTEEGMRVLTQLVATYPQGF------KVWMGPISPLLSLCHPDIIRSVINASA 115
           GH  ++ P  +G     Q++  Y + +      K+W+GP+ P+++L + + +  ++ +S 
Sbjct: 61  GHALLMKP--DGREFFQQIIE-YTEEYRHMPLLKLWVGPV-PMVALYNAENVEVILTSSK 116

Query: 116 AIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMH 175
            I       Y FLEPWLG GLL S G+KW   R+MLTP FHF IL+ ++ I NE  NI+ 
Sbjct: 117 QIDKSS--MYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILV 174

Query: 176 AKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKP-SEYIAAILELSALVSK 234
            K +   ++ +   + F +I+L  LD + +     +   Q    SEY+ A+  +S ++ +
Sbjct: 175 KKLEKHINQEA--FNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFR 232

Query: 235 RHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGV---DDFLQAKA 291
           R     L +D  Y +  +G   +++ +++H FT++VI ER   + +      D    A +
Sbjct: 233 RIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPS 292

Query: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351
           K+K   F+D+LL   D++G +LS EDIR E DTFMFEGHDTTA+ ++W LY L  +PE Q
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 352 ERCRQEVQELL-KDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD 410
           ++   E+ ++  K   P  +E  DL  L +L   +KE+LRL P VP+ +R V++D  +  
Sbjct: 353 KKVDHELDDVFGKSDRPATVE--DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG 410

Query: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
            RV+ KG   +I  +  H +P  +P+PE + P RF PEN + R P A++PFSAGPRNCIG
Sbjct: 411 YRVL-KGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIG 469

Query: 471 QTFAMAEMKVVLALTLLRFRVLPD--HTEPRRKPELVLRAEGGLWLRVE 517
           Q FA+ E K +L+  L  F +  +    E   + +L+LR   G+W++++
Sbjct: 470 QKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLK 518


>gi|239757171 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  267 bits (683), Expect = 2e-71
 Identities = 129/157 (82%), Positives = 143/157 (91%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +ACLDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV+KR+ +ILLH+DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239751683 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  267 bits (683), Expect = 2e-71
 Identities = 129/157 (82%), Positives = 143/157 (91%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +ACLDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV+KR+ +ILLH+DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239746187 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  267 bits (683), Expect = 2e-71
 Identities = 129/157 (82%), Positives = 143/157 (91%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +ACLDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV+KR+ +ILLH+DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
           [Homo sapiens]
          Length = 503

 Score =  150 bits (379), Expect = 3e-36
 Identities = 119/435 (27%), Positives = 215/435 (49%), Gaps = 37/435 (8%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFH 156
           P+L++  PD+I++V+         ++  +  +  ++ + + ++  ++W R R +L+P F 
Sbjct: 80  PMLAITDPDMIKTVLVKECYSVFTNRRPFGPVG-FMKNAISIAEDEEWKRIRSLLSPTFT 138

Query: 157 FNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHI-SLMTLDSLQKCVF--SFDS- 212
              LK  + I  +  +++    +  A  G       +H+    ++D +    F  S DS 
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVT--LKHVFGAYSMDVITSTSFGVSIDSL 196

Query: 213 -HCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRAC---RLVHDFTD 268
            + Q+   E    +L  + L        +L I    +LTP  +         +++   T 
Sbjct: 197 NNPQDPFVENTKKLLRFNPL-----DPFVLSIKVFPFLTPILEALNITVFPRKVISFLTK 251

Query: 269 AV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD-EDGKKLSDEDIRAEADTF 325
           +V  I+E R     +   DFLQ    S+          SKD E  K LSD ++ A++  F
Sbjct: 252 SVKQIKEGRLKETQKHRVDFLQLMIDSQN---------SKDSETHKALSDLELMAQSIIF 302

Query: 326 MFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCM 385
           +F G++TT+S LS+++Y LA HP+ Q++ ++E+  +L ++ P    +D +  L +L M +
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPT--YDTVLQLEYLDMVV 360

Query: 386 KESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF 445
            E+LRL P    + R   +D+ + +G  IPKG++ +I  +  HH+P  W +PE + P RF
Sbjct: 361 NETLRLFPVAMRLERVCKKDVEI-NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERF 419

Query: 446 DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELV 505
             +N     P  + PF +GPRNCIG  FA+  MK+ L   L  F       +P ++ ++ 
Sbjct: 420 SKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSF-----KPCKETQIP 474

Query: 506 LRAE-GGLWLRVEPL 519
           L+   GGL L  +P+
Sbjct: 475 LKLRFGGLLLTEKPI 489


>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 2 [Homo sapiens]
          Length = 503

 Score =  145 bits (367), Expect = 7e-35
 Identities = 104/407 (25%), Positives = 194/407 (47%), Gaps = 29/407 (7%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFH 156
           P+L +  PD+I++V+         ++     +  +L   L  +  ++W R R +L+PAF 
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEEWKRIRTLLSPAFT 138

Query: 157 FNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQE 216
               K  + I ++  +++    +  A E S  +++ +     T+D +   +F  +     
Sbjct: 139 SVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197

Query: 217 KPSE----YIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRF------RRACRLVHDF 266
            P +     +  +L+L  L        LL I    +LTP  +        +     + + 
Sbjct: 198 NPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNS 252

Query: 267 TDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFM 326
            + + + R +      VD F Q          ID     + +  K LSD ++ A++   +
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKALSDLELVAQSIIII 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMK 386
           F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D L  + +L M + 
Sbjct: 304 FAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYDALVQMEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFD 446
           E+LRL P V  ++R   +DI + +G  IPKG+  ++ ++  HH+P  W +PE + P RF 
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFS 420

Query: 447 PENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
            +N        +IPF AGPRNCIG  FA+  +K+ +   L  F   P
Sbjct: 421 KKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467


>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
           [Homo sapiens]
          Length = 503

 Score =  142 bits (357), Expect = 1e-33
 Identities = 106/405 (26%), Positives = 198/405 (48%), Gaps = 25/405 (6%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFH 156
           P+L++  PD+I++V+         ++  +  +  ++   + ++  ++W R R +L+P F 
Sbjct: 80  PVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG-FMKSAISIAEDEEWKRLRSLLSPTFT 138

Query: 157 FNILKPYMKIFNESVNIMHAKWQLLASEGSACL--DMFEHISLMTLDSLQKCVFSFDS-- 212
              LK  + I  +  +++    +  A  G      D+F   S+  + S    V + DS  
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV-NIDSLN 197

Query: 213 HCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQ 272
           + Q+   E    +L    L         L I    +L P  +     C    + T+ + +
Sbjct: 198 NPQDPFVENTKKLLRFDFL-----DPFFLSITVFPFLIPILEVLN-ICVFPREVTNFLRK 251

Query: 273 ERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD----EDGKKLSDEDIRAEADTFMFE 328
             +R   S+  D       +   +DF+ +++ S++    E  K LSD ++ A++  F+F 
Sbjct: 252 SVKRMKESRLED------TQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305

Query: 329 GHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKES 388
           G++TT+S LS+++Y LA HP+ Q++ ++E+  +L ++ P    +D +  + +L M + E+
Sbjct: 306 GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPT--YDTVLQMEYLDMVVNET 363

Query: 389 LRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPE 448
           LRL P    + R   +D+ + +G  IPKG++ +I  +  H +P  W +PE + P RF  +
Sbjct: 364 LRLFPIAMRLERVCKKDVEI-NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKK 422

Query: 449 NIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
           N     P  + PF +GPRNCIG  FA+  MK+ L   L  F   P
Sbjct: 423 NKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467


>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 1 [Homo sapiens]
          Length = 504

 Score =  141 bits (356), Expect = 1e-33
 Identities = 104/408 (25%), Positives = 194/408 (47%), Gaps = 30/408 (7%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFH 156
           P+L +  PD+I++V+         ++     +  +L   L  +  ++W R R +L+PAF 
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEEWKRIRTLLSPAFT 138

Query: 157 FNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQE 216
               K  + I ++  +++    +  A E S  +++ +     T+D +   +F  +     
Sbjct: 139 SVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197

Query: 217 KPSE----YIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRF------RRACRLVHDF 266
            P +     +  +L+L  L        LL I    +LTP  +        +     + + 
Sbjct: 198 NPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNS 252

Query: 267 TDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFM 326
            + + + R +      VD F Q          ID     + +  K LSD ++ A++   +
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKALSDLELVAQSIIII 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMK 386
           F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D L  + +L M + 
Sbjct: 304 FAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYDALVQMEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDP-FRF 445
           E+LRL P V  ++R   +DI + +G  IPKG+  ++ ++  HH+P  W +PE + P  RF
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRF 420

Query: 446 DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
             +N        +IPF AGPRNCIG  FA+  +K+ +   L  F   P
Sbjct: 421 SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 468


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score =  139 bits (350), Expect = 6e-33
 Identities = 109/407 (26%), Positives = 193/407 (47%), Gaps = 30/407 (7%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEP--WLGDGLLLSAGDKWSRHRRMLTPA 154
           P+L++  PD+IR+V+         ++     L P  ++   + L+  ++W R R +L+P 
Sbjct: 80  PVLAITDPDVIRTVLVKECYSVFTNR---RSLGPVGFMKSAISLAEDEEWKRIRSLLSPT 136

Query: 155 FHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHC 214
           F    LK    I  +  +++    +  A +G   + + +     ++D +    F  +   
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKP-VTLKDIFGAYSMDVITGTSFGVNIDS 195

Query: 215 QEKPS----EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAV 270
              P     E     L+   L       + L I    +LTP  +    +     D  + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFL-----DPLFLSIILFPFLTPVFEALNVSL-FPKDTINFL 249

Query: 271 IQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD----EDGKKLSDEDIRAEADTFM 326
            +   R   S+     L  K K + LDF+ +++ S++    E  K LSD ++ A++  F+
Sbjct: 250 SKSVNRMKKSR-----LNDKQKHR-LDFLQLMIDSQNSKETESHKALSDLELAAQSIIFI 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMK 386
           F G++TT+S LS+ LY LA HP+ Q++ ++E+  +L ++ P    +D +  + +L M + 
Sbjct: 304 FAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPP--TYDAVVQMEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFD 446
           E+LRL P    + R   +D+ + +G  IPKG + +I  +  HH+P  W +PE + P RF 
Sbjct: 362 ETLRLFPVAIRLERTCKKDVEI-NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFS 420

Query: 447 PENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
            +      P  + PF  GPRNCIG  FA+  MK+ L   L  F   P
Sbjct: 421 KKK-DSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466


>gi|5729796 cytochrome P450, family 46 [Homo sapiens]
          Length = 500

 Score =  134 bits (336), Expect = 3e-31
 Identities = 134/495 (27%), Positives = 225/495 (45%), Gaps = 58/495 (11%)

Query: 22  LLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNPTEE-GMRVLTQL 80
           LLL+G++ LLA  L  T+      R     P PPR ++  GH       +E G RVL  +
Sbjct: 5   LLLLGSAVLLAFGLCCTFVHRARSR-YEHIPGPPRPSFLLGHLPCFWKKDEVGGRVLQDV 63

Query: 81  VATYPQGFKVWMGPISPL-------LSLCHPDIIRSVINASAAIAPKDKFFYSFL----- 128
              + + +    GP+  +       + +  P+ ++  + ++     KD   Y  L     
Sbjct: 64  FLDWAKKY----GPVVRVNVFHKTSVIVTSPESVKKFLMSTKY--NKDSKMYRALQTVFG 117

Query: 129 EPWLGDGLLLSAG-DKWSRHRRMLTPAFHFNILKPYMKIFNES----VNIMHAKWQLLAS 183
           E   G GL+     ++W + RR++  AF  + L   M+ FNE     V I+ AK     +
Sbjct: 118 ERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAK-----A 172

Query: 184 EGSACLDMFEHISLMTLDSLQKCVFSFDSHC---QEKPSEYIAAILELSALVSKRHHEIL 240
           +G   + M + ++   +D L K  F  ++      +KP    A  L L  + + R+    
Sbjct: 173 DGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQ-AVKLMLEGITASRN---- 227

Query: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
               FL       +  R + R +       +Q RR  L           + +    D + 
Sbjct: 228 TLAKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALK----------RGEEVPADILT 277

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
            +L  K E+G +  DE +     TF   GH+T+A+ L++ +  L++ PE   R + EV E
Sbjct: 278 QIL--KAEEGAQ-DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDE 334

Query: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420
           ++  +  + ++++DL  L +L+  +KESLRL+PP     R + ++ ++ DG  +P     
Sbjct: 335 VIGSK--RYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI-DGVRVPGNTPL 391

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480
           L S +        + DP  ++P RF P   K R    + PFS G R+CIGQ FA  E+KV
Sbjct: 392 LFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKV 449

Query: 481 VLA--LTLLRFRVLP 493
           V+A  L  L FR++P
Sbjct: 450 VMAKLLQRLEFRLVP 464


>gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide 1
           precursor [Homo sapiens]
          Length = 531

 Score =  111 bits (277), Expect = 2e-24
 Identities = 94/378 (24%), Positives = 171/378 (45%), Gaps = 32/378 (8%)

Query: 147 HRRMLTPAFHFNILKP-----YMKIFNESVNIMHAKWQLLASE---GSACLDMFEHISLM 198
           H   L  A +  +LKP     Y   FNE ++    +   L +E   G+   DM +     
Sbjct: 153 HWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYF 212

Query: 199 TLDSLQKCVFSFDSHCQEK--PSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRF 256
            L+++   +F     C ++  P + +  +  +  +     +   L   +   + P  +R+
Sbjct: 213 ALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLP-KWTRPVLPFWKRY 271

Query: 257 RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKS--KTLDFIDVLLLSKDEDGKKLS 314
                 +  F   +I E+   + +Q     LQA      +   ++  LL S      +LS
Sbjct: 272 LDGWNAIFSFGKKLIDEKLEDMEAQ-----LQAAGPDGIQVSGYLHFLLASG-----QLS 321

Query: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
             +        +  G DTT++ L+W LYHL+K PE QE   +EV  ++   +  + +  D
Sbjct: 322 PREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHK--D 379

Query: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW 434
            AH+P L   +KE+LRL+P VP  SR + ++I + DG + PK    +   +    +P  +
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-DGFLFPKNTQFVFCHYVVSRDPTAF 438

Query: 435 PDPEVYDPFRF----DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
            +PE + P R+     P   + + P   +PF  G R C+G+  A  EM+++LA  + +++
Sbjct: 439 SEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYK 498

Query: 491 VL--PDHTEPRRKPELVL 506
           V+  P+  E +    +VL
Sbjct: 499 VVLAPETGELKSVARIVL 516


>gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  110 bits (276), Expect = 2e-24
 Identities = 63/209 (30%), Positives = 115/209 (55%), Gaps = 5/209 (2%)

Query: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
           + L+ ++I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++     
Sbjct: 325 RPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPE 383

Query: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
                  LP+L M + E+LR++PP    +R   QD  +  G+ IP G +  ++V   HH+
Sbjct: 384 FCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHHD 442

Query: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVL--ALTLLR 488
           P  WP PE ++P RF  E  ++  P  ++PF AGPR+C+G    + E+K+ L   L   R
Sbjct: 443 PEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502

Query: 489 FRVLPDHTEP-RRKPELVLRAEGGLWLRV 516
           F+  P+   P + + +  L  + G+++++
Sbjct: 503 FQACPETQVPLQLESKSALGPKNGVYIKI 531


>gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  110 bits (276), Expect = 2e-24
 Identities = 63/209 (30%), Positives = 115/209 (55%), Gaps = 5/209 (2%)

Query: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
           + L+ ++I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++     
Sbjct: 325 RPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPE 383

Query: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
                  LP+L M + E+LR++PP    +R   QD  +  G+ IP G +  ++V   HH+
Sbjct: 384 FCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHHD 442

Query: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVL--ALTLLR 488
           P  WP PE ++P RF  E  ++  P  ++PF AGPR+C+G    + E+K+ L   L   R
Sbjct: 443 PEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 502

Query: 489 FRVLPDHTEP-RRKPELVLRAEGGLWLRV 516
           F+  P+   P + + +  L  + G+++++
Sbjct: 503 FQACPETQVPLQLESKSALGPKNGVYIKI 531


>gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 3 [Homo sapiens]
          Length = 420

 Score =  109 bits (273), Expect = 5e-24
 Identities = 85/358 (23%), Positives = 169/358 (47%), Gaps = 29/358 (8%)

Query: 97  PLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFH 156
           P+L +  PD+I++V+         ++     +  +L   L  +  ++W R R +L+PAF 
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEEWKRIRTLLSPAFT 138

Query: 157 FNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQE 216
               K  + I ++  +++    +  A E S  +++ +     T+D +   +F  +     
Sbjct: 139 SVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197

Query: 217 KPSE----YIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRF------RRACRLVHDF 266
            P +     +  +L+L  L        LL I    +LTP  +        +     + + 
Sbjct: 198 NPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNS 252

Query: 267 TDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFM 326
            + + + R +      VD F Q          ID     + +  K LSD ++ A++   +
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKALSDLELVAQSIIII 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMK 386
           F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D L  + +L M + 
Sbjct: 304 FAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYDALVQMEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFR 444
           E+LRL P V  ++R   +DI + +G  IPKG+  ++ ++  HH+P  W +PE + P R
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 418


>gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide 1
           [Homo sapiens]
          Length = 544

 Score =  102 bits (255), Expect = 6e-22
 Identities = 70/245 (28%), Positives = 117/245 (47%), Gaps = 15/245 (6%)

Query: 283 VDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAE------ADTFMFEGHDTTASG 336
           + D  ++  +    DFID+ LL  +E+ K  S+     E       D F+  G DTT + 
Sbjct: 302 IKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFI-AGTDTTTNS 360

Query: 337 LSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVP 396
           L W L +++ +P+ QE+  +E++ ++       +   D A +P+    + E  RL   VP
Sbjct: 361 LLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLT--DKAQMPYTEATIMEVQRLTVVVP 418

Query: 397 VISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPL 456
           +   H+T +  +  G  IPKG + L +++  H +PA+W  PE + P RF  +  +     
Sbjct: 419 LAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKE 478

Query: 457 AFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR-VLPDHTEPRRKPELVLRAEGGLWLR 515
            FIPF  G R C+G+  A  E+ ++    +  F   LP   E  +KP  +L    GL L 
Sbjct: 479 TFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALP---EDSKKP--LLTGRFGLTLA 533

Query: 516 VEPLS 520
             P +
Sbjct: 534 PHPFN 538


>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
           [Homo sapiens]
          Length = 501

 Score =  102 bits (254), Expect = 8e-22
 Identities = 76/270 (28%), Positives = 122/270 (45%), Gaps = 26/270 (9%)

Query: 254 QRFRRACRLVHDFTDAVIQE----RRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDED 309
           Q FR A  +V+DF   +I++    R+  LP   VD +L            D +   K++ 
Sbjct: 245 QLFRNAA-VVYDFLSRLIEKASVNRKPQLPQHFVDAYL------------DEMDQGKNDP 291

Query: 310 GKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKE 369
               S E++       +  G +TT + L W +  +A +P  Q + ++E+ +L+     K 
Sbjct: 292 SSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEI-DLIMGPNGKP 350

Query: 370 IEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHH 429
             WDD   +P+    + E LR    VP+   H T +  +  G  IPKG   + +++  H 
Sbjct: 351 -SWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHF 409

Query: 430 NPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489
           +   W DPEV+ P RF   +       A +PFS G R+C+G+  A  EM +     L RF
Sbjct: 410 DEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469

Query: 490 RV-LPDHTEPRRKPELVLRAEGGLWLRVEP 518
            +  P    P  KP L      G+ L+ +P
Sbjct: 470 HLHFPHELVPDLKPRL------GMTLQPQP 493


>gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1
           isoform 1 precursor [Homo sapiens]
          Length = 514

 Score =  100 bits (250), Expect = 2e-21
 Identities = 89/374 (23%), Positives = 166/374 (44%), Gaps = 33/374 (8%)

Query: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKP--YMKI---FNESVNIMHAKWQLLASEGSA 187
           G GLL+  G+ W R R     AF   ++KP   MK+    NE +     +   L  E   
Sbjct: 144 GYGLLILEGEDWQRVR----SAFQKKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGH 199

Query: 188 CLDMFEHISLMTLDSLQKCVFS--FDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDF 245
             D++  ++  + +S+   ++   F    +    E +  I+ +  ++S     ++  ++ 
Sbjct: 200 VEDLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIMAIKTMMSTFGRMMVTPVEL 259

Query: 246 LYYL-TPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLL 304
              L T   Q    A   +     A I  R      Q   DFL            D+   
Sbjct: 260 HKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYSQQPSADFL-----------CDIY-- 306

Query: 305 SKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKD 364
                  +LS +++ A          +TTA+ L W+LY+L+++P+ Q++  +E+Q +L +
Sbjct: 307 ----HQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPE 362

Query: 365 REPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISV 424
            +    E  DL ++P+L  C+KES+RL P VP  +R + +  VL +   +PKG + +++ 
Sbjct: 363 NQVPRAE--DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGE-YALPKGTVLMLNT 419

Query: 425 FGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLAL 484
                +   + D   + P R+  E  ++ +P A +PF  G R CIG+  A  ++ + L  
Sbjct: 420 QVLGSSEDNFEDSSQFRPERWLQEK-EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCW 478

Query: 485 TLLRFRVLPDHTEP 498
            + ++ +     EP
Sbjct: 479 IVRKYDIQATDNEP 492


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,993,544
Number of Sequences: 37866
Number of extensions: 1036295
Number of successful extensions: 3141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2884
Number of HSP's gapped (non-prelim): 112
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.