Guide to the Human Genome
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Search of human proteins with 6005830

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6005830 plakophilin 3 [Homo sapiens]
         (797 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6005830 plakophilin 3 [Homo sapiens]                              1570   0.0  
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]                  291   1e-78
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...   272   1e-72
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                  270   3e-72
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]                   259   7e-69
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ...   259   7e-69
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                    259   9e-69
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                    259   9e-69
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]                   247   4e-65
gi|4502247 armadillo repeat protein [Homo sapiens]                    243   7e-64
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]               242   9e-64
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]               242   9e-64
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]               242   9e-64
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]               242   9e-64
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]              242   9e-64
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]               242   9e-64
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]               242   9e-64
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]               242   9e-64
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                242   9e-64
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]              242   9e-64
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]              237   3e-62
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]             237   3e-62
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]             237   3e-62
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              45   3e-04
gi|4504811 junction plakoglobin [Homo sapiens]                         42   0.002
gi|12056468 junction plakoglobin [Homo sapiens]                        42   0.002
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                40   0.007
gi|31657114 armadillo repeat containing 4 [Homo sapiens]               39   0.015
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD...    38   0.032
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD...    38   0.032

>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score = 1570 bits (4065), Expect = 0.0
 Identities = 797/797 (100%), Positives = 797/797 (100%)

Query: 1   MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQ 60
           MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQ
Sbjct: 1   MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQ 60

Query: 61  PRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWS 120
           PRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWS
Sbjct: 61  PRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWS 120

Query: 121 SRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLS 180
           SRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLS
Sbjct: 121 SRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLS 180

Query: 181 LRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPS 240
           LRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPS
Sbjct: 181 LRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPS 240

Query: 241 RTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGF 300
           RTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGF
Sbjct: 241 RTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGF 300

Query: 301 NSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSL 360
           NSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSL
Sbjct: 301 NSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSL 360

Query: 361 QAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELR 420
           QAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELR
Sbjct: 361 QAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELR 420

Query: 421 KNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATG 480
           KNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATG
Sbjct: 421 KNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATG 480

Query: 481 FLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYD 540
           FLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYD
Sbjct: 481 FLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYD 540

Query: 541 EMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLE 600
           EMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLE
Sbjct: 541 EMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLE 600

Query: 601 WLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPL 660
           WLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPL
Sbjct: 601 WLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPL 660

Query: 661 LDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVN 720
           LDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVN
Sbjct: 661 LDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVN 720

Query: 721 IIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKL 780
           IIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKL
Sbjct: 721 IIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKL 780

Query: 781 HRDFRAKGYRKEDFLGP 797
           HRDFRAKGYRKEDFLGP
Sbjct: 781 HRDFRAKGYRKEDFLGP 797


>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
          Length = 837

 Score =  291 bits (746), Expect = 1e-78
 Identities = 231/819 (28%), Positives = 388/819 (47%), Gaps = 65/819 (7%)

Query: 19  SLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNG-----AAEPE--- 70
           SLALPS+ +L   G+ G   + +++ R+QEQV+  L + G+    NG     ++ PE   
Sbjct: 29  SLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVY 88

Query: 71  ----PEAETARGTSR--GQYHTLQAGFSSRSQGLSGDKTSGF------------RPIAKP 112
                E +   G S     Y  L+AG ++  +G  G  T+ +             P+ + 
Sbjct: 89  NLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRL 148

Query: 113 AYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRP--VSFHERGGV 170
             SP S   R+    S  +    +  G +         A   PP   R   V     G  
Sbjct: 149 EISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTT 208

Query: 171 GSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSR----- 225
             +  +DT   +           ++  VS+ +  +  +      Y R  +S S       
Sbjct: 209 SRQRHFDTYHRQY----------QHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEK 258

Query: 226 ----AGGLDWPEATEVSPSRTIRAPAVRTLQRFQSS-HRSRGVGGAVPGAVLEPVARAPS 280
                 GL   +   + P + +           QSS H +R +  A P   ++   R   
Sbjct: 259 ENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAH 318

Query: 281 VRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASD--PNLQVL 338
           +     +   SG+L          S  T  +L +   ++ L  AV  L A    P+    
Sbjct: 319 LTVGQAAAGGSGNLLTER------STFTDSQLGNADMEMTLERAVSMLEADHMLPSRISA 372

Query: 339 GAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLA 398
            A +IQH+C+  + A+K+   L+ + +L++L    N++VQR   GA+RNL++++ DNKL 
Sbjct: 373 AATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLE 432

Query: 399 LVEENGIFELLRTLREQDD-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLS 457
           + E NG+  LL+ L++  D E +K +TG+LWNLSS+D LK+ +  + L  LT+ ++ P S
Sbjct: 433 VAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFS 492

Query: 458 GAGGPPLIQQNAS-EAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDA 516
           G       + N   + +IFYN TG LRN+SSA    R+ MR C GL+D+LV  +   +  
Sbjct: 493 GWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIAD 552

Query: 517 GKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRR 576
            + +DK+ EN VC+L NLSY+L  E+P    Q +  + R         + +GCF  +SR+
Sbjct: 553 YQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRN--IQTDNNKSIGCFGSRSRK 610

Query: 577 LRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNIT 636
           ++E       +   E   +PKG+EWLW   ++ +Y  L+ +  +  +T EA+ GALQN+T
Sbjct: 611 VKE---QYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAK-SVRNYTQEASLGALQNLT 666

Query: 637 AGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKV 696
           AG       +++  +++E  L      +   D    ++   L+RNLSRN   ++E++ + 
Sbjct: 667 AGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKET 726

Query: 697 VSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRD 756
           +  L+  +P +V       E   +    LNN++  S   ARDLL   G++K++ I    D
Sbjct: 727 LPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI-SAGD 785

Query: 757 SPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFL 795
           +  S K+S+AAS LL +LW + +LH  ++   ++K DF+
Sbjct: 786 AYASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV 824


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
            plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score =  272 bits (695), Expect = 1e-72
 Identities = 177/501 (35%), Positives = 270/501 (53%), Gaps = 29/501 (5%)

Query: 315  GFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHAN 374
            G+ D +LP  ++ L    P++Q   AAY+QH C+ D   K + R    +  LV L +H  
Sbjct: 546  GWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRM 605

Query: 375  QEVQRHATGAMRNLIYDNA--DNKLALVEENGIFELLRTLREQDD-ELRKNVTGILWNLS 431
             EV R A GA+RNL+Y  A  DNK+AL    GI  L+R LR+  D E+R+ VTG+LWNLS
Sbjct: 606  TEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLS 665

Query: 432  SSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPL-----IQQNASEAEIFYNATGFLRNLS 486
            S D LK  + +D L  LT+ V+ P SG    PL     IQ ++S+  +  NATG LRN+S
Sbjct: 666  SCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQ--VLRNATGCLRNVS 723

Query: 487  SASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSA 546
            SA +  R++MREC GL DAL+  I  AL + + + K+VEN VC+LRNLSYRL  E     
Sbjct: 724  SAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQG- 782

Query: 547  LQRLEGRGRRDLAGAPPGEV-------VGCFTPQSRRLRELPLAADALTFAEVSKDPKGL 599
                +  G  +L G   GE         GC+  + ++ +            + ++ PKG+
Sbjct: 783  ----QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGI 838

Query: 600  EWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNP 659
            + LW P IV  Y  LL  C  N  T E AAGALQN+ AG  +W+ V  R A+ +E+ L  
Sbjct: 839  QMLWHPSIVKPYLTLLSECS-NPDTLEGAAGALQNLAAGSWKWS-VYIRAAVRKEKGLPI 896

Query: 660  LLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPG-----SVGEKSPP 714
            L++ +R  +   + ++   +RN++ + RNK+ +    +  L+ +LPG     +   K+  
Sbjct: 897  LVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMS 956

Query: 715  AEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANL 774
             + +  +   L+ ++  +   A+ L    G+ KL+ I K +    S K  +AAS +L ++
Sbjct: 957  DDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSM 1016

Query: 775  WQYNKLHRDFRAKGYRKEDFL 795
            WQY  L   ++  G+ +  F+
Sbjct: 1017 WQYRDLRSLYKKDGWSQYHFV 1037


>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score =  270 bits (691), Expect = 3e-72
 Identities = 231/863 (26%), Positives = 388/863 (44%), Gaps = 109/863 (12%)

Query: 19  SLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNG-----AAEPE--- 70
           SLALPS+ +L   G+ G   + +++ R+QEQV+  L + G+    NG     ++ PE   
Sbjct: 29  SLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVY 88

Query: 71  ----PEAETARGTSR--GQYHTLQAGFSSRSQGLSGDKTSGF------------RPIAKP 112
                E +   G S     Y  L+AG ++  +G  G  T+ +             P+ + 
Sbjct: 89  NLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRL 148

Query: 113 AYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRP--VSFHERGGV 170
             SP S   R+    S  +    +  G +         A   PP   R   V     G  
Sbjct: 149 EISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTT 208

Query: 171 GSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSR----- 225
             +  +DT   +           ++  VS+ +  +  +      Y R  +S S       
Sbjct: 209 SRQRHFDTYHRQY----------QHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEK 258

Query: 226 ----AGGLDWPEATEVSPSRTIRAPAVRTLQRFQSS-HRSRGVGGAVPGAVLEPVARAPS 280
                 GL   +   + P + +           QSS H +R +  A P   ++   R   
Sbjct: 259 ENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAH 318

Query: 281 VRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASD--PNLQVL 338
           +     +   SG+L          S  T  +L +   ++ L  AV  L A    P+    
Sbjct: 319 LTVGQAAAGGSGNLLTER------STFTDSQLGNADMEMTLERAVSMLEADHMLPSRISA 372

Query: 339 GAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLA 398
            A +IQH+C+  + A+K+   L+ + +L++L    N++VQR   GA+RNL++++ DNKL 
Sbjct: 373 AATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLE 432

Query: 399 LVEENGIFELLRTLREQDD-ELRKNVT--------------------------------- 424
           + E NG+  LL+ L++  D E +K +T                                 
Sbjct: 433 VAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRIT 492

Query: 425 -----------GILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNAS-EA 472
                      G+LWNLSS+D LK+ +  + L  LT+ ++ P SG       + N   + 
Sbjct: 493 RSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDF 552

Query: 473 EIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLR 532
           +IFYN TG LRN+SSA    R+ MR C GL+D+LV  +   +   + +DK+ EN VC+L 
Sbjct: 553 DIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILH 612

Query: 533 NLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEV 592
           NLSY+L  E+P    Q +  + R         + +GCF  +SR+++E       +   E 
Sbjct: 613 NLSYQLEAELPEKYSQNIYIQNRN--IQTDNNKSIGCFGSRSRKVKE---QYQDVPMPEE 667

Query: 593 SKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALE 652
             +PKG+EWLW   ++ +Y  L+ +  +  +T EA+ GALQN+TAG       +++  ++
Sbjct: 668 KSNPKGVEWLWHSIVIRMYLSLIAK-SVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQ 726

Query: 653 QERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS 712
           +E  L      +   D    ++   L+RNLSRN   ++E++ + +  L+  +P +V    
Sbjct: 727 KESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTD 786

Query: 713 PPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLA 772
              E   +    LNN++  S   ARDLL   G++K++ I    D+  S K+S+AAS LL 
Sbjct: 787 LLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI-SAGDAYASNKASKAASVLLY 845

Query: 773 NLWQYNKLHRDFRAKGYRKEDFL 795
           +LW + +LH  ++   ++K DF+
Sbjct: 846 SLWAHTELHHAYKKAQFKKTDFV 868


>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
          Length = 726

 Score =  259 bits (662), Expect = 7e-69
 Identities = 172/499 (34%), Positives = 265/499 (53%), Gaps = 29/499 (5%)

Query: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356
           S+G  R   ++ S  +DI+     +P AV+YL + D   Q +GA YIQH C+ D +AK+Q
Sbjct: 225 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 282

Query: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416
              L  + +LV L    NQ VQ+ A GA+RNL++ +  NKL    +NGI E +  LR   
Sbjct: 283 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 342

Query: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474
           + E++K +TG+LWNLSS+D LK+ L  D L  L D V+ P SG   G   + +   + E+
Sbjct: 343 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 402

Query: 475 FYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNL 534
           F+NATG LRNLSSA  A RQ MR   GL+D+L+  + + + A +C+DKSVEN +CVL NL
Sbjct: 403 FFNATGCLRNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461

Query: 535 SYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLR----ELPLAADALTFA 590
           SYRL D   P+  ++LE   R            GCF+ +S ++     + PL        
Sbjct: 462 SYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNKSDKMMNNNYDCPL-------P 510

Query: 591 EVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLA 650
           E   +PKG  WL+    +  Y  L+ + + +  T EA AGALQN+TA     +  +S+L 
Sbjct: 511 EEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACAGALQNLTASKGLMSSGMSQLI 569

Query: 651 LEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGE 710
             +E+ L  +   +++ +   +RS   L+ N+SR+      M  +V   +   L    G 
Sbjct: 570 GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGN 629

Query: 711 KSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSL 770
            S   ++L +    + NL+ + P  A+       L  +I + +   SP   K++ AA  L
Sbjct: 630 TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP---KAAEAARLL 686

Query: 771 LANLWQYNKLHRDFRAKGY 789
           L+++W   +L    R +G+
Sbjct: 687 LSDMWSSKELQGVLRQQGF 705


>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
           sapiens]
          Length = 625

 Score =  259 bits (662), Expect = 7e-69
 Identities = 172/499 (34%), Positives = 265/499 (53%), Gaps = 29/499 (5%)

Query: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356
           S+G  R   ++ S  +DI+     +P AV+YL + D   Q +GA YIQH C+ D +AK+Q
Sbjct: 124 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 181

Query: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416
              L  + +LV L    NQ VQ+ A GA+RNL++ +  NKL    +NGI E +  LR   
Sbjct: 182 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 241

Query: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474
           + E++K +TG+LWNLSS+D LK+ L  D L  L D V+ P SG   G   + +   + E+
Sbjct: 242 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 301

Query: 475 FYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNL 534
           F+NATG LRNLSSA  A RQ MR   GL+D+L+  + + + A +C+DKSVEN +CVL NL
Sbjct: 302 FFNATGCLRNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360

Query: 535 SYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLR----ELPLAADALTFA 590
           SYRL D   P+  ++LE   R            GCF+ +S ++     + PL        
Sbjct: 361 SYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNKSDKMMNNNYDCPL-------P 409

Query: 591 EVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLA 650
           E   +PKG  WL+    +  Y  L+ + + +  T EA AGALQN+TA     +  +S+L 
Sbjct: 410 EEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACAGALQNLTASKGLMSSGMSQLI 468

Query: 651 LEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGE 710
             +E+ L  +   +++ +   +RS   L+ N+SR+      M  +V   +   L    G 
Sbjct: 469 GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGN 528

Query: 711 KSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSL 770
            S   ++L +    + NL+ + P  A+       L  +I + +   SP   K++ AA  L
Sbjct: 529 TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP---KAAEAARLL 585

Query: 771 LANLWQYNKLHRDFRAKGY 789
           L+++W   +L    R +G+
Sbjct: 586 LSDMWSSKELQGVLRQQGF 604


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score =  259 bits (661), Expect = 9e-69
 Identities = 169/492 (34%), Positives = 260/492 (52%), Gaps = 16/492 (3%)

Query: 318  DIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEV 377
            D +LP  +  L    P++Q   AAY+QH C+ D   K +   L  +  LV L +H   EV
Sbjct: 527  DPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEV 586

Query: 378  QRHATGAMRNLIYDNA--DNKLALVEENGIFELLRTLREQ-DDELRKNVTGILWNLSSSD 434
            Q++A GA+RNL++  +  +NK+A+    GI  LLR LR+  D E+R+ VTG+LWNLSS D
Sbjct: 587  QKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCD 646

Query: 435  HLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQA 491
             +K  + RD L  LT+ V+ P SG         +  + +   +  N TG LRNLSSA + 
Sbjct: 647  AVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEE 706

Query: 492  TRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLE 551
             R++MR C GLVD+L+  I+  ++    + K+VEN VC LRNLSYRL  E+P + L  L 
Sbjct: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766

Query: 552  GRGRRDLAG---APPGEVVGCFTPQSRRLRELPLAAD---ALTFAEVSKDPKGLEWLWSP 605
                 DL G           C+  + ++ +  P             +SK PKG+E LW P
Sbjct: 767  ELD--DLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824

Query: 606  QIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVR 665
             +V  Y  LL     N  T E +AG+LQN++AG+ ++A  + R A+ +E+ L  L++ +R
Sbjct: 825  SVVKPYLTLLAESS-NPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLR 882

Query: 666  TADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVL 725
              +   + S+   +RN++ + RNK+ +    +  L+ +LPG  G      E +  I   L
Sbjct: 883  MDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCAL 942

Query: 726  NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785
            + +   +   A+ L    G+ KL+ I K R    S K  +AA+ +L  LWQY  L   ++
Sbjct: 943  HEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYK 1002

Query: 786  AKGYRKEDFLGP 797
              G+ +  F+ P
Sbjct: 1003 KDGWNQNHFITP 1014


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score =  259 bits (661), Expect = 9e-69
 Identities = 169/492 (34%), Positives = 260/492 (52%), Gaps = 16/492 (3%)

Query: 318  DIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEV 377
            D +LP  +  L    P++Q   AAY+QH C+ D   K +   L  +  LV L +H   EV
Sbjct: 527  DPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEV 586

Query: 378  QRHATGAMRNLIYDNA--DNKLALVEENGIFELLRTLREQ-DDELRKNVTGILWNLSSSD 434
            Q++A GA+RNL++  +  +NK+A+    GI  LLR LR+  D E+R+ VTG+LWNLSS D
Sbjct: 587  QKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCD 646

Query: 435  HLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQA 491
             +K  + RD L  LT+ V+ P SG         +  + +   +  N TG LRNLSSA + 
Sbjct: 647  AVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEE 706

Query: 492  TRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLE 551
             R++MR C GLVD+L+  I+  ++    + K+VEN VC LRNLSYRL  E+P + L  L 
Sbjct: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766

Query: 552  GRGRRDLAG---APPGEVVGCFTPQSRRLRELPLAAD---ALTFAEVSKDPKGLEWLWSP 605
                 DL G           C+  + ++ +  P             +SK PKG+E LW P
Sbjct: 767  ELD--DLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824

Query: 606  QIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVR 665
             +V  Y  LL     N  T E +AG+LQN++AG+ ++A  + R A+ +E+ L  L++ +R
Sbjct: 825  SVVKPYLTLLAESS-NPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLR 882

Query: 666  TADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVL 725
              +   + S+   +RN++ + RNK+ +    +  L+ +LPG  G      E +  I   L
Sbjct: 883  MDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCAL 942

Query: 726  NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785
            + +   +   A+ L    G+ KL+ I K R    S K  +AA+ +L  LWQY  L   ++
Sbjct: 943  HEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYK 1002

Query: 786  AKGYRKEDFLGP 797
              G+ +  F+ P
Sbjct: 1003 KDGWNQNHFITP 1014


>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
          Length = 747

 Score =  247 bits (630), Expect = 4e-65
 Identities = 172/520 (33%), Positives = 265/520 (50%), Gaps = 50/520 (9%)

Query: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356
           S+G  R   ++ S  +DI+     +P AV+YL + D   Q +GA YIQH C+ D +AK+Q
Sbjct: 225 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 282

Query: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416
              L  + +LV L    NQ VQ+ A GA+RNL++ +  NKL    +NGI E +  LR   
Sbjct: 283 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 342

Query: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474
           + E++K +TG+LWNLSS+D LK+ L  D L  L D V+ P SG   G   + +   + E+
Sbjct: 343 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 402

Query: 475 FYNATGFLR---------------------NLSSASQATRQKMRECHGLVDALVTSINHA 513
           F+NATG LR                     NLSSA  A RQ MR   GL+D+L+  + + 
Sbjct: 403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNC 461

Query: 514 LDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQ 573
           + A +C+DKSVEN +CVL NLSYRL D   P+  ++LE   R            GCF+ +
Sbjct: 462 VAASRCDDKSVENCMCVLHNLSYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNK 517

Query: 574 SRRLR----ELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAA 629
           S ++     + PL        E   +PKG  WL+    +  Y  L+ + + +  T EA A
Sbjct: 518 SDKMMNNNYDCPL-------PEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACA 569

Query: 630 GALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNK 689
           GALQN+TA     +  +S+L   +E+ L  +   +++ +   +RS   L+ N+SR+    
Sbjct: 570 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH 629

Query: 690 DEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLI 749
             M  +V   +   L    G  S   ++L +    + NL+ + P  A+       L  +I
Sbjct: 630 RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNII 689

Query: 750 FIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGY 789
            + +   SP   K++ AA  LL+++W   +L    R +G+
Sbjct: 690 NLCRSSASP---KAAEAARLLLSDMWSSKELQGVLRQQGF 726


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score =  243 bits (619), Expect = 7e-64
 Identities = 170/498 (34%), Positives = 268/498 (53%), Gaps = 26/498 (5%)

Query: 318 DIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEV 377
           D +LP  +  L      ++   AAY+QH C+ +   K++ R L+ +P LV L +H   EV
Sbjct: 357 DPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEV 416

Query: 378 QRHATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDH 435
           +R A GA+RNL Y  + DNK A+ +  G+  L+R LR  +D+E+R+ VTG LWNLSS + 
Sbjct: 417 RRRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEP 476

Query: 436 LKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQAT 492
           LK  +    L+ LT  V+ P SG    P       +AE   +F N +G LRN+SS     
Sbjct: 477 LKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEA 536

Query: 493 RQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMP--------- 543
           R+++REC GLVDAL+ ++  A+     ++KSVEN VC++RNLSY ++ E+P         
Sbjct: 537 RRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAE 596

Query: 544 PSALQRLEG--RGRRDLAGAPPG-EVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLE 600
           P  L    G  R RRD A    G +    +  Q ++  E+    D L   + ++  KG E
Sbjct: 597 PGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFE 656

Query: 601 WLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPL 660
            L+ P++V LY  LL     N +T EAAAGALQN++AG+  WA  + R  + +ER L  L
Sbjct: 657 LLYQPEVVRLYLSLLTESR-NFNTLEAAAGALQNLSAGNWMWATYI-RATVRKERGLPVL 714

Query: 661 LDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPA----E 716
           ++ +++     +R++   +RNLS + RNKD + +  ++ L+  +  +     P A    +
Sbjct: 715 VELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEED 774

Query: 717 VLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQ 776
            +V ++  ++ +V  S   AR LL   G+  L+ +     S  S + ++AAS +L  +W 
Sbjct: 775 TVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVA---SSQSVREAKAASHVLQTVWS 831

Query: 777 YNKLHRDFRAKGYRKEDF 794
           Y +L    +  G+ K  F
Sbjct: 832 YKELRGTLQKDGWTKARF 849


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 506 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 564

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 565 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 621

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 739

Query: 792 EDF 794
            DF
Sbjct: 740 SDF 742


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 506 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 564

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 565 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 621

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 739

Query: 792 EDF 794
            DF
Sbjct: 740 SDF 742


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 506 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 564

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 565 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 621

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 739

Query: 792 EDF 794
            DF
Sbjct: 740 SDF 742


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 506 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 564

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 565 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 621

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 739

Query: 792 EDF 794
            DF
Sbjct: 740 SDF 742


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 506 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 564

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 565 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 621

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 739

Query: 792 EDF 794
            DF
Sbjct: 740 SDF 742


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 607 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 665

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 666 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 722

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 840

Query: 792 EDF 794
            DF
Sbjct: 841 SDF 843


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 607 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 665

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 666 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 722

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 840

Query: 792 EDF 794
            DF
Sbjct: 841 SDF 843


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 607 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 665

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 666 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 722

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 840

Query: 792 EDF 794
            DF
Sbjct: 841 SDF 843


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 607 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 665

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 666 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 722

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 840

Query: 792 EDF 794
            DF
Sbjct: 841 SDF 843


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score =  242 bits (618), Expect = 9e-64
 Identities = 158/483 (32%), Positives = 256/483 (53%), Gaps = 14/483 (2%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRL 614
             +  G       G    + ++  E P A D + F + +   +G E L+ P++V +Y  L
Sbjct: 607 VANNTGPHAASCFGAKKGKGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVVRIYISL 665

Query: 615 LQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTADHHQLR 673
           L+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +       ++
Sbjct: 666 LKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNEHERVVK 722

Query: 674 SLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVLNNLVVA 731
           + +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +N ++  
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782

Query: 732 SPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRK 791
           +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +    +G++K
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLEKEGWKK 840

Query: 792 EDF 794
            DF
Sbjct: 841 SDF 843


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score =  237 bits (605), Expect = 3e-62
 Identities = 158/489 (32%), Positives = 257/489 (52%), Gaps = 20/489 (4%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGC------FTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIV 608
             +  G       G       +  + ++  E P A D + F + +   +G E L+ P++V
Sbjct: 506 VANNTGPHAASCFGAKKGKDEWFSRGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVV 564

Query: 609 GLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTA 667
            +Y  LL+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +   
Sbjct: 565 RIYISLLKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNE 621

Query: 668 DHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVL 725
               +++ +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681

Query: 726 NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785
           N ++  +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +   
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLE 739

Query: 786 AKGYRKEDF 794
            +G++K DF
Sbjct: 740 KEGWKKSDF 748


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score =  237 bits (605), Expect = 3e-62
 Identities = 158/489 (32%), Positives = 257/489 (52%), Gaps = 20/489 (4%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 266 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 325

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 326 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 385

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 386 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 445

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 446 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 505

Query: 555 RRDLAGAPPGEVVGC------FTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIV 608
             +  G       G       +  + ++  E P A D + F + +   +G E L+ P++V
Sbjct: 506 VANNTGPHAASCFGAKKGKDEWFSRGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVV 564

Query: 609 GLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTA 667
            +Y  LL+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +   
Sbjct: 565 RIYISLLKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNE 621

Query: 668 DHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVL 725
               +++ +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681

Query: 726 NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785
           N ++  +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +   
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLE 739

Query: 786 AKGYRKEDF 794
            +G++K DF
Sbjct: 740 KEGWKKSDF 748


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score =  237 bits (605), Expect = 3e-62
 Identities = 158/489 (32%), Positives = 257/489 (52%), Gaps = 20/489 (4%)

Query: 320 DLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQR 379
           +LP  +  L      ++   AAY+QH CY +   K   R L+ +P LV L +H  +EV  
Sbjct: 367 ELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHL 426

Query: 380 HATGAMRNLIYD-NADNKLALVEENGIFELLRTLRE-QDDELRKNVTGILWNLSSSDHLK 437
            A GA++N+ +  + DNK+A+   +G+  L+R LR+ +D +L + +TG LWNLSS D +K
Sbjct: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIK 486

Query: 438 DRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQATRQ 494
             +    L  LTD V+ P SG    P         E   +  N  G LRN+SS     R+
Sbjct: 487 MEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARR 546

Query: 495 KMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRG 554
           K+REC GLVDAL+  +   +     + K VEN VC+LRNLSY+++ E+P +   +     
Sbjct: 547 KLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPN 606

Query: 555 RRDLAGAPPGEVVGC------FTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIV 608
             +  G       G       +  + ++  E P A D + F + +   +G E L+ P++V
Sbjct: 607 VANNTGPHAASCFGAKKGKDEWFSRGKKPIEDP-ANDTVDFPKRTSPARGYELLFQPEVV 665

Query: 609 GLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWA-GVLSRLALEQERILNPLLDRVRTA 667
            +Y  LL+  +      EA+AGA+QN+ AG  RW  G   R AL QE+ L+ + D +   
Sbjct: 666 RIYISLLKESK-TPAILEASAGAIQNLCAG--RWTYGRYIRSALRQEKALSAIADLLTNE 722

Query: 668 DHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS--PPAEVLVNIIAVL 725
               +++ +G +RNL+ +ARNK+ +    + +L++ LPG     S     + +++I+  +
Sbjct: 723 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 782

Query: 726 NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785
           N ++  +  AA+ L    G+ KL+ I K  +   SEK  RAA+ +L  +W Y +L +   
Sbjct: 783 NEVIAENLEAAKKLRETQGIEKLVLINKSGNR--SEKEVRAAALVLQTIWGYKELRKPLE 840

Query: 786 AKGYRKEDF 794
            +G++K DF
Sbjct: 841 KEGWKKSDF 849


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 5/112 (4%)

Query: 361 QAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELR 420
           Q +P+L++L    N+EV+  A  A+ NL   N  N  A  E +GI  L+  L  + D   
Sbjct: 356 QGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAI 415

Query: 421 KNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEA 472
            N   +L N++  + L+  +       +   ++SPL  A    ++Q  A+ A
Sbjct: 416 ANAATVLTNMAMQEPLRLNIQN---HDIMHAIISPLRSAN--TVVQSKAALA 462



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 83/407 (20%), Positives = 157/407 (38%), Gaps = 40/407 (9%)

Query: 366 LVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTG 425
           +V + N   +E+   A  A+        +NK  L+E   +  L + L  +D  +R+N T 
Sbjct: 30  VVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATM 89

Query: 426 ILWNLSSSDHLKDRL-----ARDTLEQLT---DLVLSPLSGAGGPPLIQQNASEAEIFYN 477
           I   L+S++ +K  L         + QL    ++V+   +      +  +  S+ +IF +
Sbjct: 90  IFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEH 149

Query: 478 A--TGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVE-NAVCVLRNL 534
                 +R LSS     ++   EC          I + +   +C  K  E NA+  + +L
Sbjct: 150 GGLEPLIRLLSSPDPDVKKNSMEC----------IYNLVQDFQCRAKLQELNAIPPILDL 199

Query: 535 SYRLYDEMPPSALQRL----EGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFA 590
               Y  +   AL+ L      +  R +     G        +++ L +L + A     A
Sbjct: 200 LKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEA----LA 255

Query: 591 EVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLA 650
            ++   + ++ +   Q  G   +LL   E N    +    A + IT   +      +R  
Sbjct: 256 VIANCLEDMDTMVQIQQTGGLKKLLSFAE-NSTIPDIQKNAAKAIT---KAAYDPENRKL 311

Query: 651 LEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGE 710
             ++ +   L+  + + +     + +  I  +  N+ +KD  + + +  LI+ L      
Sbjct: 312 FHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLL------ 365

Query: 711 KSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLI-FIKKKRD 756
           KS   EV       L NL   +P  A      DG+  LI  +  KRD
Sbjct: 366 KSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRD 412


>gi|4504811 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/217 (23%), Positives = 89/217 (41%), Gaps = 21/217 (9%)

Query: 321 LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRH 380
           L   V  L  ++P    +    +Q   Y +  +K    +      LV++  + + E    
Sbjct: 270 LQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLW 329

Query: 381 ATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRL 440
            T  +  ++     NK A+VE  G+  L + L      L +N    L NLS         
Sbjct: 330 TTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDV-----AT 384

Query: 441 ARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECH 500
            ++ LE +  ++++ LS             +  +   ATG L NL+  +   +  + +  
Sbjct: 385 KQEGLESVLKILVNQLS-----------VDDVNVLTCATGTLSNLTCNNSKNKTLVTQNS 433

Query: 501 GLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYR 537
           G V+AL+ +I  A D    +D   E AVC LR+L+ R
Sbjct: 434 G-VEALIHAILRAGD----KDDITEPAVCALRHLTSR 465


>gi|12056468 junction plakoglobin [Homo sapiens]
          Length = 745

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/217 (23%), Positives = 89/217 (41%), Gaps = 21/217 (9%)

Query: 321 LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRH 380
           L   V  L  ++P    +    +Q   Y +  +K    +      LV++  + + E    
Sbjct: 270 LQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLW 329

Query: 381 ATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRL 440
            T  +  ++     NK A+VE  G+  L + L      L +N    L NLS         
Sbjct: 330 TTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDV-----AT 384

Query: 441 ARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECH 500
            ++ LE +  ++++ LS             +  +   ATG L NL+  +   +  + +  
Sbjct: 385 KQEGLESVLKILVNQLS-----------VDDVNVLTCATGTLSNLTCNNSKNKTLVTQNS 433

Query: 501 GLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYR 537
           G V+AL+ +I  A D    +D   E AVC LR+L+ R
Sbjct: 434 G-VEALIHAILRAGD----KDDITEPAVCALRHLTSR 465


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 46/195 (23%), Positives = 82/195 (42%), Gaps = 28/195 (14%)

Query: 353 AKKQARSLQAVPRLVKLF--------NHANQEVQRHATGAMRNLIYDNADNKLALVEENG 404
           A  +   LQAV  L+++         +  N  ++R+A   + NL + +  NK  L    G
Sbjct: 430 AMNELGGLQAVAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRG 489

Query: 405 IFE-LLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPP 463
             E ++  L    +EL + V+ IL NLS    +  +        +T LV   L       
Sbjct: 490 CMEAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQCVL------- 542

Query: 464 LIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKS 523
                A++     +    L NLS+ S   +  + +  G +  LV+++ +     KC+  S
Sbjct: 543 ----RATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTY-----KCQSNS 593

Query: 524 ---VENAVCVLRNLS 535
              +E+   +LRN+S
Sbjct: 594 LAIIESGGGILRNVS 608


>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
          Length = 1044

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 84/415 (20%), Positives = 156/415 (37%), Gaps = 61/415 (14%)

Query: 321  LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRH 380
            +P   + L  S  N+ +     +Q +C S+   +   ++ + +  LVK  N  N+++Q H
Sbjct: 634  IPLLARLLKTSHENMLIPVVGTLQ-ECASEENYRAAIKAERIIENLVKNLNSENEQLQEH 692

Query: 381  ATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELR-KNVTGILWNLS-SSDHLKD 438
               A+     D     L  +   G+  L   L   D++ R   VTG +W  S S +++  
Sbjct: 693  CAMAIYQCAEDKETRDLVRL-HGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTK 751

Query: 439  RLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRE 498
                  +E L  L+                    E+  N  G L       +  R  +R+
Sbjct: 752  FREYKAIETLVGLLTD---------------QPEEVLVNVVGALGECCQ-ERENRVIVRK 795

Query: 499  CHGLV----------DALVTSINHALDAGKCEDKSVE-----NAVCVLRNLSYRLYDEMP 543
            C G+            AL+ ++  A+ A   E +S+      + V +L +L    + ++ 
Sbjct: 796  CGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVK 855

Query: 544  PSALQRLEG--RGRRDLAGAPPGEVVGCFTPQSRRLREL-------PLAADALTFAEVSK 594
             SA   L    +  +D      GE+V  F      +  L        LA+       ++K
Sbjct: 856  ASAAWALCPCIKNAKD-----AGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAK 910

Query: 595  DPKGLEWLWSPQIVGLYNRL--LQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALE 652
            D + L  +    +V L ++L      +L  H  EA +            W    +R+A  
Sbjct: 911  DQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCM--------WG--RNRVAFG 960

Query: 653  QERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGS 707
            + + + PL+  +++ D +  R+    +  LS +A N   M       L+  + GS
Sbjct: 961  EHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGS 1015


>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 38.1 bits (87), Expect = 0.032
 Identities = 58/226 (25%), Positives = 95/226 (42%), Gaps = 32/226 (14%)

Query: 325 VKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGA 384
           VK+L  +   LQ+L     + K    A+   QA        LV +      E     T  
Sbjct: 291 VKFLAITTDCLQILAYGNQESKLIILASGGPQA--------LVNIMRTYTYEKLLWTTSR 342

Query: 385 MRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDT 444
           +  ++   + NK A+VE  G+  L   L +    L +N    L NLS +        ++ 
Sbjct: 343 VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDA-----ATKQEG 397

Query: 445 LEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECH-GLV 503
           +E L   ++  L            + +  +   A G L NL+  +   + KM  C  G +
Sbjct: 398 MEGLLGTLVQLL-----------GSDDINVVTCAAGILSNLTCNNY--KNKMMVCQVGGI 444

Query: 504 DALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYD-EMPPSALQ 548
           +ALV ++   L AG  ED   E A+C LR+L+ R  + EM  +A++
Sbjct: 445 EALVRTV---LRAGDRED-ITEPAICALRHLTSRHQEAEMAQNAVR 486


>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
           [Homo sapiens]
          Length = 781

 Score = 38.1 bits (87), Expect = 0.032
 Identities = 58/226 (25%), Positives = 95/226 (42%), Gaps = 32/226 (14%)

Query: 325 VKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGA 384
           VK+L  +   LQ+L     + K    A+   QA        LV +      E     T  
Sbjct: 291 VKFLAITTDCLQILAYGNQESKLIILASGGPQA--------LVNIMRTYTYEKLLWTTSR 342

Query: 385 MRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDT 444
           +  ++   + NK A+VE  G+  L   L +    L +N    L NLS +        ++ 
Sbjct: 343 VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDA-----ATKQEG 397

Query: 445 LEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECH-GLV 503
           +E L   ++  L            + +  +   A G L NL+  +   + KM  C  G +
Sbjct: 398 MEGLLGTLVQLL-----------GSDDINVVTCAAGILSNLTCNNY--KNKMMVCQVGGI 444

Query: 504 DALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYD-EMPPSALQ 548
           +ALV ++   L AG  ED   E A+C LR+L+ R  + EM  +A++
Sbjct: 445 EALVRTV---LRAGDRED-ITEPAICALRHLTSRHQEAEMAQNAVR 486


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,688,682
Number of Sequences: 37866
Number of extensions: 1416250
Number of successful extensions: 5529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 5207
Number of HSP's gapped (non-prelim): 222
length of query: 797
length of database: 18,247,518
effective HSP length: 110
effective length of query: 687
effective length of database: 14,082,258
effective search space: 9674511246
effective search space used: 9674511246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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