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Search of human proteins with 6005812
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005812 dual specificity phosphatase 10 isoform a [Homo
sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 969 0.0
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 286 2e-77
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 286 2e-77
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 186 5e-47
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 183 3e-46
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 181 1e-45
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 180 3e-45
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 167 3e-41
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 161 1e-39
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 154 2e-37
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 152 9e-37
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 131 1e-30
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 127 3e-29
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 106 5e-23
gi|37674210 slingshot 2 [Homo sapiens] 100 5e-21
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 99 9e-21
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 99 9e-21
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 99 9e-21
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 98 2e-20
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 95 1e-19
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 92 1e-18
gi|239582767 slingshot homolog 3 [Homo sapiens] 90 5e-18
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 87 3e-17
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 86 6e-17
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 82 8e-16
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 82 8e-16
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 82 8e-16
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 81 2e-15
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 81 2e-15
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 80 3e-15
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 969 bits (2505), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY 60
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY
Sbjct: 1 MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTY 60
Query: 61 MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN 120
MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN
Sbjct: 61 MPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNN 120
Query: 121 NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF 180
NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF
Sbjct: 121 NENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF 180
Query: 181 MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT 240
MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT
Sbjct: 181 MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT 240
Query: 241 NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA 300
NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA
Sbjct: 241 NEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA 300
Query: 301 SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL 360
SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL
Sbjct: 301 SAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPL 360
Query: 361 YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI 420
YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI
Sbjct: 361 YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI 420
Query: 421 AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET 480
AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET
Sbjct: 421 AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET 480
Query: 481 VV 482
VV
Sbjct: 481 VV 482
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 286 bits (733), Expect = 2e-77
Identities = 140/140 (100%), Positives = 140/140 (100%)
Query: 343 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 402
MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 403 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
Query: 463 NNGVTPRILTPKLMGVETVV 482
NNGVTPRILTPKLMGVETVV
Sbjct: 121 NNGVTPRILTPKLMGVETVV 140
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 286 bits (733), Expect = 2e-77
Identities = 140/140 (100%), Positives = 140/140 (100%)
Query: 343 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 402
MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 403 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
Query: 463 NNGVTPRILTPKLMGVETVV 482
NNGVTPRILTPKLMGVETVV
Sbjct: 121 NNGVTPRILTPKLMGVETVV 140
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 186 bits (471), Expect = 5e-47
Identities = 113/314 (35%), Positives = 172/314 (54%), Gaps = 25/314 (7%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSF-KRIFSK 231
+++DCRP Y SHI+ A+++ I RRLQ+G + V L + E +D F +R +
Sbjct: 35 LLMDCRPQELYESSHIESAINV-AIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTD 93
Query: 232 EIIVYDENTNEPSRVMPSQP-LHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQ- 289
+++YDE++++ + + L ++L+ LK EG L+GG S F+ C+ +L
Sbjct: 94 TVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDG 153
Query: 290 -------------LQECREVGGGASAASSLLPQPIPTTPDIENAELT--------PILPF 328
L R +S S L + + D + + L+ ILPF
Sbjct: 154 SCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPF 213
Query: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
L+LG +D+ +LD ++ I Y++NVT +LP G F YK++P +D QNL Q+F
Sbjct: 214 LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFP 273
Query: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
EA FI+EA G+L+HC AG+SRS T+ +AYLM+ ++M DAY VK K+ ISPN
Sbjct: 274 EAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPN 333
Query: 449 LNFMGQLLEFEEDL 462
NFMGQLL+FE L
Sbjct: 334 FNFMGQLLDFERTL 347
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 183 bits (465), Expect = 3e-46
Identities = 105/314 (33%), Positives = 167/314 (53%), Gaps = 25/314 (7%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFK-RIFSK 231
+++DCRP + SHI+ A+++ + RRL++G + + +I K+ F R +
Sbjct: 73 LLLDCRPHELFESSHIETAINL-AIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAA 131
Query: 232 EIIVYDENTNE--PSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQ 289
+++YDE T E P P+ L ++L+ L+ +G + L+GG + F+ + C+ ++
Sbjct: 132 TVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVD 191
Query: 290 LQ---------------------ECREVGGGASAASSLLPQPIPTTPDIENAELTPILPF 328
+C + SS P + A ILP+
Sbjct: 192 SSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPY 251
Query: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
L+LG +D+ +LD + + I Y++NVT +LP G F YK++P +D QNL Q+F
Sbjct: 252 LYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFP 311
Query: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
EA FI+EA G+L+HC AG+SRS T+ +AYLM+ +++ DAY FVK K+ ISPN
Sbjct: 312 EAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPN 371
Query: 449 LNFMGQLLEFEEDL 462
NFMGQLL+FE L
Sbjct: 372 FNFMGQLLDFERTL 385
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 181 bits (459), Expect = 1e-45
Identities = 106/292 (36%), Positives = 163/292 (55%), Gaps = 17/292 (5%)
Query: 171 GPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFS 230
GP++ID R F+EYN H+ +V+I C K+ +RRLQQGK+T+ +LI + +
Sbjct: 26 GPLVIDSRSFVEYNSWHVLSSVNI-CCSKLVKRRLQQGKVTIAELIQ-PAARSQVEATEP 83
Query: 231 KEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQL 290
++++VYD++T + S + L I+L L +L GG ++F LC+
Sbjct: 84 QDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCE----- 138
Query: 291 QECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGY 350
G A+ L QP P + LT ILP L+LG+++D + D M + I Y
Sbjct: 139 ------GKPAALLPMSLSQPCLPVPSVG---LTRILPHLYLGSQKDVLNKDLMTQNGISY 189
Query: 351 VINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQA 410
V+N + P + + R+P D+ + L + +++ EFI++A +++HC A
Sbjct: 190 VLNASNSCPKPDFICES-RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLA 248
Query: 411 GVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
G+SRSATI IAY+MK M+ DAY+FVK +RP ISPN NF+GQLLE+E L
Sbjct: 249 GISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 180 bits (456), Expect = 3e-45
Identities = 106/294 (36%), Positives = 171/294 (58%), Gaps = 22/294 (7%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
++ID RPF+EYN SHI A++INC+ K+ +RRLQQ K+ + +LI K S++
Sbjct: 27 LLIDSRPFVEYNTSHILEAININCS-KLMKRRLQQDKVLITELIQ-HSAKHKVDIDCSQK 84
Query: 233 IIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQE 292
++VYD+++ + + + L ++L L++ +L GG + F + LC+
Sbjct: 85 VVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGK----- 139
Query: 293 CREVGGGASAASSLLPQPI--PTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGY 350
S+L+P I P P + N T ILP L+LG ++D + + MQ+ IGY
Sbjct: 140 -----------STLVPTCISQPCLP-VANIGPTRILPNLYLGCQRDVLNKELMQQNGIGY 187
Query: 351 VINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQA 410
V+N + P + ++ R+P DS + + + +++ +FIE+A +L+HC A
Sbjct: 188 VLNASNTCPKPDFIPES-HFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLA 246
Query: 411 GVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNN 464
G+SRSATI IAY+MK M++ +AY+FVK KRP ISPN NF+GQLL++E+ + N
Sbjct: 247 GISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKN 300
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 167 bits (422), Expect = 3e-41
Identities = 101/314 (32%), Positives = 167/314 (53%), Gaps = 36/314 (11%)
Query: 167 LPSQGP-VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREG-KDS 224
LPS G +++DCRPF+ ++ +I G+V++ C + RR +G +++ ++ E +
Sbjct: 39 LPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRA--KGSVSLEQILPAEEEVRAR 96
Query: 225 FKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKR--EGKEPLVLKGGLSSFKQNHEN 282
+ +IVYDE + + + +V+++L+R E + +LKGG F +
Sbjct: 97 LRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPE 156
Query: 283 LCDNSLQLQECREVGGGASAASSLLPQPIPT--------------TPDIENAELTPILPF 328
C + L + +P P+P TP + ILPF
Sbjct: 157 FCSKTKAL--------------AAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPF 202
Query: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
L+LG+ A D + L I ++NV++ P H+E G + YK +P D++K ++ +F
Sbjct: 203 LYLGSAYHAARRDMLDALGITALLNVSSDCP-NHFE-GHYQYKCIPVEDNHKADISSWFM 260
Query: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
EA E+I+ C +L+HCQAG+SRSATI +AYLM R+ + +A++FVK +R IISPN
Sbjct: 261 EAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPN 320
Query: 449 LNFMGQLLEFEEDL 462
+FMGQLL+FE +
Sbjct: 321 FSFMGQLLQFESQV 334
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 161 bits (408), Expect = 1e-39
Identities = 108/335 (32%), Positives = 169/335 (50%), Gaps = 58/335 (17%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
+++DCR Y + I GA+ + + RRL++G ++V L+ +
Sbjct: 23 LLLDCRSRELYESARIGGALSV-ALPALLLRRLRRGSLSVRALLP----GPPLQPPPPAP 77
Query: 233 IIVYDENTN---------EPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENL 283
+++YD+ E L +L+ L+ EG L+GG S F+ +L
Sbjct: 78 VLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHL 137
Query: 284 CDNSLQLQECREVGGGASAASSLLPQPIPTT--------PDIENAE-------------- 321
C+ SL G A ++ + +P P+P D +AE
Sbjct: 138 CETSL--------AGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDS 189
Query: 322 --LTP------------ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGL 367
TP ILP L+LG+ +D+ +L+++ +L I Y++NVT +LP + + G
Sbjct: 190 EGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGD 249
Query: 368 FNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHT 427
F+YK++P +D QNL ++F EA EFI+EA G+L+HC AGVSRS T+ +AYLM+
Sbjct: 250 FHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKL 309
Query: 428 RMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
+++ DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 310 HLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 154 bits (388), Expect = 2e-37
Identities = 97/297 (32%), Positives = 154/297 (51%), Gaps = 16/297 (5%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
+++DCR F +N HI G+V++ + + RR +G + + ++ E +
Sbjct: 25 LLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRA--KGAMGLEHIVPNAELRGRLLAGAYHA 82
Query: 233 IIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLV--LKGGLSSFKQNHENLCDNS--- 287
+++ DE + L + +L RE + V LKGG +F + LC
Sbjct: 83 VVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTP 142
Query: 288 --LQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQR 345
L L V A + S +TP + ILPFL+LG+ A D +
Sbjct: 143 MGLSLPLSTSVPDSAESGCSSC-----STPLYDQGGPVEILPFLYLGSAYHASRKDMLDA 197
Query: 346 LNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLL 405
L I +INV+ + P H+E G + YK +P D++K ++ +F EA +FI+ G +
Sbjct: 198 LGITALINVSANCP-NHFE-GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVF 255
Query: 406 IHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
+HCQAG+SRSATI +AYLM+ R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 256 VHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV 312
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 152 bits (383), Expect = 9e-37
Identities = 95/291 (32%), Positives = 148/291 (50%), Gaps = 14/291 (4%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
+++DCRPF+ + + H++ A + + RR + L+ R + R
Sbjct: 28 LLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELAR 87
Query: 233 IIVYDENTNEPSRVMPSQPLHIVLESLKREGKEP----LVLKGGLSSFKQNHENLCDNSL 288
+V DE + + + P P H++L +L E + L+GG F+ +LC +
Sbjct: 88 AVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEA- 146
Query: 289 QLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNI 348
G S + S P + ILP+LFLG+ + DL +Q I
Sbjct: 147 PAPALPPTGDKTSRSDS-------RAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGI 199
Query: 349 GYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHC 408
V+NV+ P H+E GLF YK +P D+ + +F+EA FI+ G +L+HC
Sbjct: 200 TAVLNVSASCP-NHFE-GLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHC 257
Query: 409 QAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 459
QAG+SRSATI +AYLM+ R+ + +A+ FVK +R +ISPN +FMGQLL+FE
Sbjct: 258 QAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFE 308
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 131 bits (330), Expect = 1e-30
Identities = 88/325 (27%), Positives = 161/325 (49%), Gaps = 37/325 (11%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSK- 231
V++DCRP++ + S+++G++++N + + RR + G ++ ++ + R+ +
Sbjct: 24 VVLDCRPYLAFAASNVRGSLNVNL-NSVVLRRARGGAVSARYVLPDEAAR---ARLLQEG 79
Query: 232 -----EIIVYDENTNEPSRVMPSQPLHIVLESLKR---EGKEPLVLKGGLSSFKQNHENL 283
++V D+ + ++ +VL SL G LKGG +F +
Sbjct: 80 GGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPEC 139
Query: 284 CDNSLQLQECREVGGGASAASSLLPQPIPTT---PDIENAELTPILPFLFLGNEQDAQDL 340
C + + + E A S +P+ P + ILPFL+LG+ A
Sbjct: 140 CVDVKPISQ--EKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKC 197
Query: 341 DTMQRLNIGYVINVT--------THLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFE 392
+ + L+I ++NV+ THL +YK +P DS+ ++ +F+EA +
Sbjct: 198 EFLANLHITALLNVSRRTSEACATHL----------HYKWIPVEDSHTADISSHFQEAID 247
Query: 393 FIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFM 452
FI+ + G +L+HC+AG+SRS TI +AYLMK + + +A+ ++K +R ++SPN FM
Sbjct: 248 FIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFM 307
Query: 453 GQLLEFEEDLNNGVTPRILTPKLMG 477
GQLL++E ++ TP P G
Sbjct: 308 GQLLQYESEILPS-TPNPQPPSCQG 331
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 127 bits (318), Expect = 3e-29
Identities = 73/207 (35%), Positives = 110/207 (53%), Gaps = 30/207 (14%)
Query: 270 KGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQPIPT--------------TP 315
+GG F + C + L + +P P+P TP
Sbjct: 53 QGGYERFSSEYPEFCSKTKAL--------------AAIPPPVPPSATEPLDLGCSSCGTP 98
Query: 316 DIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPA 375
+ ILPFL+LG+ A D + L I ++NV++ P H+E G + YK +P
Sbjct: 99 LHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCP-NHFE-GHYQYKCIPV 156
Query: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435
D++K ++ +F EA E+I+ C +L+HCQAG+SRSATI +AYLM R+ + +A+
Sbjct: 157 EDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAF 216
Query: 436 KFVKGKRPIISPNLNFMGQLLEFEEDL 462
+FVK +R IISPN +FMGQLL+FE +
Sbjct: 217 EFVKQRRSIISPNFSFMGQLLQFESQV 243
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 106 bits (264), Expect = 5e-23
Identities = 59/149 (39%), Positives = 83/149 (55%), Gaps = 8/149 (5%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGL---FNYKRLPATDSNKQ 381
I P+L LG++ A DLDT+++ + +++NV Y E F YK + D +
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVA-----YGVENAFLSDFTYKSISILDLPET 123
Query: 382 NLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGK 441
N+ YF E FEFIEEA + +L+HC AGVSR+A IVI +LM + + T A+ VK
Sbjct: 124 NILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNA 183
Query: 442 RPIISPNLNFMGQLLEFEEDLNNGVTPRI 470
RP I PN FM QL ++E + RI
Sbjct: 184 RPSICPNSGFMEQLRTYQEGKESNKCDRI 212
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 99.8 bits (247), Expect = 5e-21
Identities = 50/137 (36%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query: 323 TPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQN 382
T I +FLG+E +A +L+ +Q + Y++NVT + ++ G+F Y + D +
Sbjct: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREID--NFFPGVFEYHNIRVYDEEATD 366
Query: 383 LRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 442
L Y+ + ++FI +A + G L+HC+ GVSRSA+ VIAY MK + AY +VK +R
Sbjct: 367 LLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERR 426
Query: 443 PIISPNLNFMGQLLEFE 459
+ PN +FM QL E++
Sbjct: 427 TVTKPNPSFMRQLEEYQ 443
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 99.0 bits (245), Expect = 9e-21
Identities = 53/135 (39%), Positives = 78/135 (57%), Gaps = 2/135 (1%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384
I L+LG+E +A +L+ +Q + Y++NVT + ++ GLF Y + D +L
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLL 369
Query: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
++ EA+ FI +A + L+HC+ GVSRSA+ VIAY MK + AY +VK KR I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 445 ISPNLNFMGQLLEFE 459
PN FM QL E+E
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 99.0 bits (245), Expect = 9e-21
Identities = 53/135 (39%), Positives = 78/135 (57%), Gaps = 2/135 (1%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384
I L+LG+E +A +L+ +Q + Y++NVT + ++ GLF Y + D +L
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLL 380
Query: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
++ EA+ FI +A + L+HC+ GVSRSA+ VIAY MK + AY +VK KR I
Sbjct: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
Query: 445 ISPNLNFMGQLLEFE 459
PN FM QL E+E
Sbjct: 441 TRPNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 99.0 bits (245), Expect = 9e-21
Identities = 53/135 (39%), Positives = 78/135 (57%), Gaps = 2/135 (1%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384
I L+LG+E +A +L+ +Q + Y++NVT + ++ GLF Y + D +L
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREID--NFFPGLFAYHNIRVYDEETTDLL 369
Query: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
++ EA+ FI +A + L+HC+ GVSRSA+ VIAY MK + AY +VK KR I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 445 ISPNLNFMGQLLEFE 459
PN FM QL E+E
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 97.8 bits (242), Expect = 2e-20
Identities = 54/139 (38%), Positives = 83/139 (59%), Gaps = 3/139 (2%)
Query: 322 LTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQ 381
+ ILP L++GN +DA+D + + + + ++++V H +G+ Y +PA DS Q
Sbjct: 5 MNKILPGLYIGNFKDARDAEQLSKNKVTHILSV--HDSARPMLEGV-KYLCIPAADSPSQ 61
Query: 382 NLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGK 441
NL ++F+E+ +FI E G+ L+HC AGVSRS T+VIAY+M T DA V+
Sbjct: 62 NLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAG 121
Query: 442 RPIISPNLNFMGQLLEFEE 460
R +PN+ F QL EFE+
Sbjct: 122 RSCANPNVGFQRQLQEFEK 140
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 95.1 bits (235), Expect = 1e-19
Identities = 54/166 (32%), Positives = 86/166 (51%), Gaps = 5/166 (3%)
Query: 300 ASAASSLLPQPIPTTPDIENAEL---TPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTT 356
+S S LP+ + I ++ I LFLG A + +Q I ++N T
Sbjct: 2 SSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATI 61
Query: 357 HLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSA 416
+P +++ + F Y ++P D + YF+ + I + L+HC AGVSRSA
Sbjct: 62 EIPNFNWPQ--FEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSA 119
Query: 417 TIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
T+ IAYLMK + + +AY +VK +RP+I PN+ F QL+++E L
Sbjct: 120 TLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQL 165
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 92.0 bits (227), Expect = 1e-18
Identities = 53/138 (38%), Positives = 78/138 (56%), Gaps = 5/138 (3%)
Query: 322 LTPILPFLFLGNEQDAQDLDTMQRLNIGYVINV-TTHLPLYHYEKGLFNYKRLPATDSNK 380
+T +LP L+LGN DA+DLD + R I ++I++ + PL Y R+P D+ +
Sbjct: 5 MTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQD----ITYLRIPVADTPE 60
Query: 381 QNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKG 440
++++F+E FI G L+HC AG+SRS TIV AY+M T + D + +K
Sbjct: 61 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA 120
Query: 441 KRPIISPNLNFMGQLLEF 458
RPI +PN F QL EF
Sbjct: 121 TRPIANPNPGFRQQLEEF 138
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 89.7 bits (221), Expect = 5e-18
Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLR 384
I P L+LG+E +A +L+ +QR + +++N+ + ++ E+ F Y + D L
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQLL 389
Query: 385 QYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
+++E FIE A G +L+HC+ GVSRSA V+AY MK ++ A + V+ RPI
Sbjct: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
Query: 445 ISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGV 478
PN F+ QL ++ L + K+ GV
Sbjct: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGV 483
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 87.0 bits (214), Expect = 3e-17
Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 20/183 (10%)
Query: 288 LQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLN 347
L +Q+ ++ S SL QP + P +++GN AQD+ +Q+L
Sbjct: 7 LSVQDLNDLLSDGSGCYSLPSQPC-----------NEVTPRIYVGNASVAQDIPKLQKLG 55
Query: 348 IGYVINVTTHLPLYH-------YEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQC 400
I +V+N H Y+ Y + A D+ + NL YFE A +FI++A
Sbjct: 56 ITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQ 115
Query: 401 GKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 459
G +L+HC+ G SRS T+VIAYLM +M + A V+ R I PN F+ QL +
Sbjct: 116 KNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE-IGPNDGFLAQLCQLN 174
Query: 460 EDL 462
+ L
Sbjct: 175 DRL 177
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 86.3 bits (212), Expect = 6e-17
Identities = 49/143 (34%), Positives = 75/143 (52%), Gaps = 2/143 (1%)
Query: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
LFL N A D + I ++N + + +E Y ++P TD+ L +F+
Sbjct: 29 LFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEG--IQYIKVPVTDARDSRLYDFFD 86
Query: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
+ I L+HC AGVSRSA++ +AYLMK+ M++ DA+ + K +RPII PN
Sbjct: 87 PIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPN 146
Query: 449 LNFMGQLLEFEEDLNNGVTPRIL 471
F QL+ +E L N T R++
Sbjct: 147 NGFWEQLINYEFKLFNNNTVRMI 169
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 8e-16
Identities = 53/158 (33%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Query: 321 ELTPILPFLFLGNEQDAQD--LDTMQRLNIGYVINVTTHLPLYHYEKG---LFNYKRLPA 375
E+ ILP LFLG A L +Q+ I ++I + ++ + LF Y L
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435
D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+ M DA+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 473
+V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 8e-16
Identities = 53/158 (33%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Query: 321 ELTPILPFLFLGNEQDAQD--LDTMQRLNIGYVINVTTHLPLYHYEKG---LFNYKRLPA 375
E+ ILP LFLG A L +Q+ I ++I + ++ + LF Y L
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435
D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+ M DA+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 473
+V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 8e-16
Identities = 53/158 (33%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Query: 321 ELTPILPFLFLGNEQDAQD--LDTMQRLNIGYVINVTTHLPLYHYEKG---LFNYKRLPA 375
E+ ILP LFLG A L +Q+ I ++I + ++ + LF Y L
Sbjct: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
Query: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435
D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+ M DA+
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 473
+V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 81.3 bits (199), Expect = 2e-15
Identities = 39/73 (53%), Positives = 50/73 (68%)
Query: 390 AFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNL 449
AF +EA G+L+HC AG+SRS T+ +AYLM+ ++M DAY VK K+ ISPN
Sbjct: 129 AFYLEDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNF 188
Query: 450 NFMGQLLEFEEDL 462
NFMGQLL+FE L
Sbjct: 189 NFMGQLLDFERTL 201
Score = 49.3 bits (116), Expect = 8e-06
Identities = 30/93 (32%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Query: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSF-KRIFSK 231
+++DCRP Y SHI+ A+++ I RRLQ+G + V L + E +D F +R +
Sbjct: 35 LLMDCRPQELYESSHIESAINV-AIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTD 93
Query: 232 EIIVYDENTNEPSRVMPSQP-LHIVLESLKREG 263
+++YDE++++ + + L ++L+ LK EG
Sbjct: 94 TVVLYDESSSDWNENTGGESVLGLLLKKLKDEG 126
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 80.9 bits (198), Expect = 2e-15
Identities = 49/141 (34%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Query: 322 LTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQ 381
L+ I L++ N A + + I VINV+ + YE Y ++P DS
Sbjct: 20 LSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYED--IQYMQVPVADSPNS 77
Query: 382 NLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGK 441
L +F+ + I L+HC AGVSRSA + +AYLMK+ M++ DA+ + K
Sbjct: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
Query: 442 RPIISPNLNFMGQLLEFEEDL 462
RPII PN F QL+ +E L
Sbjct: 138 RPIIRPNSGFWEQLIHYEFQL 158
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 80.5 bits (197), Expect = 3e-15
Identities = 54/146 (36%), Positives = 81/146 (55%), Gaps = 5/146 (3%)
Query: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHL---PLYHYEKGLFNYKRLPATDSNKQ 381
+ P L+LG++ A + ++RL I +V+N + YE Y + A DS
Sbjct: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
Query: 382 NLRQYFEEAFEFIEEA-HQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKG 440
++ +F+ A +FI A Q G +L+HC GVSRSAT+V+AYLM + +T+ +A K VK
Sbjct: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
Query: 441 KRPIISPNLNFMGQLLEFEEDLNNGV 466
R II PN F+ QLL + L G+
Sbjct: 185 HRGII-PNRGFLRQLLALDRRLRQGL 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,091,368
Number of Sequences: 37866
Number of extensions: 893667
Number of successful extensions: 3489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 3211
Number of HSP's gapped (non-prelim): 261
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.