Guide to the Human Genome
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Search of human proteins with 59858535

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|59858535 trefoil factor interactions(z) 1 [Homo sapiens]
         (184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|59858535 trefoil factor interactions(z) 1 [Homo sapiens]           380   e-106
gi|94538357 18 kDa antrum mucosa protein [Homo sapiens]                74   5e-14
gi|169164045 PREDICTED: similar to hCG1782458 [Homo sapiens]           40   0.001
gi|169163256 PREDICTED: similar to hCG1782458 [Homo sapiens]           40   0.001
gi|156627559 tenomodulin [Homo sapiens]                                39   0.002
gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precur...    35   0.048
gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precurs...    35   0.048
gi|149999608 surfactant protein C [Homo sapiens]                       34   0.062
gi|32698950 hypothetical protein LOC283870 [Homo sapiens]              32   0.24 
gi|116812614 glycerol-3-phosphate acyltransferase 2, mitochondri...    28   4.5  
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]         28   5.8  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           27   7.6  
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]            27   7.6  
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]     27   9.9  

>gi|59858535 trefoil factor interactions(z) 1 [Homo sapiens]
          Length = 184

 Score =  380 bits (975), Expect = e-106
 Identities = 184/184 (100%), Positives = 184/184 (100%)

Query: 1   MKILVAFLVVLTIFGIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSS 60
           MKILVAFLVVLTIFGIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSS
Sbjct: 1   MKILVAFLVVLTIFGIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSS 60

Query: 61  TTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKY 120
           TTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKY
Sbjct: 61  TTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKY 120

Query: 121 NPLESLIKDVDWFLLGSPIEKLCKHIPLYKGEVVENTHNVGAGGCAKAGLLGILGISICA 180
           NPLESLIKDVDWFLLGSPIEKLCKHIPLYKGEVVENTHNVGAGGCAKAGLLGILGISICA
Sbjct: 121 NPLESLIKDVDWFLLGSPIEKLCKHIPLYKGEVVENTHNVGAGGCAKAGLLGILGISICA 180

Query: 181 DIHV 184
           DIHV
Sbjct: 181 DIHV 184


>gi|94538357 18 kDa antrum mucosa protein [Homo sapiens]
          Length = 199

 Score = 74.3 bits (181), Expect = 5e-14
 Identities = 49/183 (26%), Positives = 92/183 (50%), Gaps = 4/183 (2%)

Query: 1   MKILVAFLVVLTIFGIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSS 60
           MK  + F  +L +F   +      N+   +NN G+ Q++V+++NE N A ++ + G  S 
Sbjct: 15  MKFTIVFAGLLGVFLAPALANYNINVNDDNNNAGSGQQSVSVNNEHNVANVDNNNGWDSW 74

Query: 61  TTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQAL-DNMFSSKYTWVK 119
            +I+DY +G+ A+R+  ++ C + KM+ + +P + +L   + EK+             + 
Sbjct: 75  NSIWDYGNGFAATRLFQKKTCIVHKMNKEVMPSIQSLDALVKEKKLQGKGPGGPPPKGLM 134

Query: 120 YNPLESLIKDVDWFLLGSPIEKLCKHIPLYKG-EVVENTHNVGAGGCAKAGLLGILGISI 178
           Y+   + + D+  F  G  I  +C+ IP Y   E+ E +    +G C    +L I+ IS 
Sbjct: 135 YSVNPNKVDDLSKF--GKNIANMCRGIPTYMAEEMQEASLFFYSGTCYTTSVLWIVDISF 192

Query: 179 CAD 181
           C D
Sbjct: 193 CGD 195


>gi|169164045 PREDICTED: similar to hCG1782458 [Homo sapiens]
          Length = 399

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 71  IASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKYNPLESLIKDV 130
           + ++V ++ AC + +MD    P L+++   + +KQA     S++   + Y  L S +K++
Sbjct: 162 LVAKVFNKMACVLARMDKAVFPSLDDISKAL-DKQAFKYYPSTR--GLTYTVLPSWVKNL 218

Query: 131 DWFLLGSPIEKLCKHIPLYKGEVVE--NTHNVGAGGCAKAGLLGILGISIC 179
             +  G PI+ +C+  P Y  +  +      + +  C +  LL  +G+ IC
Sbjct: 219 AQY--GKPIKNMCRDDPTYFAQQQKEGTALAIDSNSCFEIQLLSFMGLFIC 267


>gi|169163256 PREDICTED: similar to hCG1782458 [Homo sapiens]
          Length = 399

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 71  IASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKYNPLESLIKDV 130
           + ++V ++ AC + +MD    P L+++   + +KQA     S++   + Y  L S +K++
Sbjct: 162 LVAKVFNKMACVLARMDKAVFPSLDDISKAL-DKQAFKYYPSTR--GLTYTVLPSWVKNL 218

Query: 131 DWFLLGSPIEKLCKHIPLYKGEVVE--NTHNVGAGGCAKAGLLGILGISIC 179
             +  G PI+ +C+  P Y  +  +      + +  C +  LL  +G+ IC
Sbjct: 219 AQY--GKPIKNMCRDDPTYFAQQQKEGTALAIDSNSCFEIQLLSFMGLFIC 267


>gi|156627559 tenomodulin [Homo sapiens]
          Length = 317

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 6/120 (5%)

Query: 31  NNGGNVQETVTIDNEKNTAIINIHAGSCSSTTIFDYKHGYIASRVLSRRACFILKMDHQN 90
           +NG   +  + ID    T I     G+  +  + D+K+GY     +  + CFI K   + 
Sbjct: 70  SNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFI-KTQIKV 128

Query: 91  IPPLNNLQWYIYEKQAL-DNMFSSKYTWVKYNPLESLIKDVDWFLLGSPIEKLCKHIPLY 149
           IP  +  +  I E + +    F     WV   P E  I++ D FL  S I ++C ++ +Y
Sbjct: 129 IPEFSEPEEEIDENEEITTTFFEQSVIWV---PAEKPIENRD-FLKNSKILEICDNVTMY 184


>gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precursor
           [Homo sapiens]
          Length = 333

 Score = 34.7 bits (78), Expect = 0.048
 Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 16/142 (11%)

Query: 15  GIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSSTTIFDYKHGYIASR 74
           G  SH Y V   +S   NG     ++ ID   N     + +G+  +  + D+++G    R
Sbjct: 67  GSDSHIYNVHYTMSI--NGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIR 124

Query: 75  VLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKYN-------PLESLI 127
                 C+I       IP +  +      KQ++ +    K   VKY         ++  +
Sbjct: 125 FAGGEKCYIKAQVKARIPEVGAV-----TKQSISSKLEGKIMPVKYEENSLIWVAVDQPV 179

Query: 128 KDVDWFLLGSPIEKLCKHIPLY 149
           KD  +  L S + +LC  +P++
Sbjct: 180 KDNSF--LSSKVLELCGDLPIF 199


>gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precursor
           [Homo sapiens]
          Length = 334

 Score = 34.7 bits (78), Expect = 0.048
 Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 16/142 (11%)

Query: 15  GIQSHGYEVFNIISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSSTTIFDYKHGYIASR 74
           G  SH Y V   +S   NG     ++ ID   N     + +G+  +  + D+++G    R
Sbjct: 67  GSDSHIYNVHYTMSI--NGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIR 124

Query: 75  VLSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSKYTWVKYN-------PLESLI 127
                 C+I       IP +  +      KQ++ +    K   VKY         ++  +
Sbjct: 125 FAGGEKCYIKAQVKARIPEVGAV-----TKQSISSKLEGKIMPVKYEENSLIWVAVDQPV 179

Query: 128 KDVDWFLLGSPIEKLCKHIPLY 149
           KD  +  L S + +LC  +P++
Sbjct: 180 KDNSF--LSSKVLELCGDLPIF 199


>gi|149999608 surfactant protein C [Homo sapiens]
          Length = 197

 Score = 34.3 bits (77), Expect = 0.062
 Identities = 35/159 (22%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 3   ILVAFLVVLTIFGIQSHGYEVFN-----IISPSNNGGNVQETVTIDNEK-NTAIINIHAG 56
           ++V  L+V+ I G    G  +       ++  S      Q+ + +      TA  +I + 
Sbjct: 40  VVVVVLIVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGS- 98

Query: 57  SCSSTTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIY------EKQALDNM 110
             +   ++DY+   IA +      C+I+K+  ++IP L  L   ++        QA   +
Sbjct: 99  --TGLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAV 156

Query: 111 FSSKYTWVKYNPLESLIKDVDWFLLGSPIEKLCKHIPLY 149
            +SK    +     S     D   LG  +  LC  +PLY
Sbjct: 157 PTSKLGQAEGRDAGSAPSGGDPAFLGMAVSTLCGEVPLY 195


>gi|32698950 hypothetical protein LOC283870 [Homo sapiens]
          Length = 228

 Score = 32.3 bits (72), Expect = 0.24
 Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 16/161 (9%)

Query: 3   ILVAFLVVLTIFGIQSHGY------------EVFNIISPSNNGGNVQETVTIDNEKNTAI 50
           +L+  L+VL   GI + G             +   +  PS +     +T+ +D  +N A 
Sbjct: 33  LLLLLLLVLAAVGIVAGGLLGSAQGPPKPRLQTLRMTLPSPHMPRPNQTILVDVARNAAT 92

Query: 51  INIHA--GSCSSTTIFDYKHGYIASRVLSRRACFILKMDHQNIPPLNNLQWYIYEKQALD 108
           I +     + S   +FD + G I  R    + CF+  M+  +   L  L      ++A  
Sbjct: 93  ITVTPPQSNHSWAVLFDGQSGCICYRPEEHQVCFLRLMEDSDRETLRLLVDTSKVQEAWV 152

Query: 109 NMFSSKYTWVKYNPLESLIKDVDWFLLGSPIEKLCKHIPLY 149
               + +T        SL  +VD    G+ +++LC   P+Y
Sbjct: 153 PSQDTHHTQELLAVQGSL--EVDPAQAGALVQRLCMRTPIY 191


>gi|116812614 glycerol-3-phosphate acyltransferase 2, mitochondrial
           [Homo sapiens]
          Length = 795

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 76  LSRRACFILKMDHQNIPPLNNLQWYIYEKQALDNMFSSK 114
           L RR C+ L    Q+IPP  ++   I E   + N+ S +
Sbjct: 89  LVRRLCYFLWSLEQHIPPCQDVPQKIMESTGVQNLLSGR 127


>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
          Length = 977

 Score = 27.7 bits (60), Expect = 5.8
 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 8/101 (7%)

Query: 34  GNVQETVTIDNEKNTAIINIHAGSCSSTTIFDYKHGYIASRVLSRRACFILKMDHQNIPP 93
           G   E +  +++K    +  HAG  SS+      HG     +  +  C     + Q + P
Sbjct: 650 GMTHEDIVQESKKYWQQMEAHAGKASSSMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVEP 709

Query: 94  LNNLQW--------YIYEKQALDNMFSSKYTWVKYNPLESL 126
             +L++        +  E++ L  M  +K  WV   PL S+
Sbjct: 710 DKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSI 750


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 27.3 bits (59), Expect = 7.6
 Identities = 13/29 (44%), Positives = 19/29 (65%), Gaps = 1/29 (3%)

Query: 77   SRRACFILKMDHQN-IPPLNNLQWYIYEK 104
            SR ACFI +  HQN + P+ N++ YI  +
Sbjct: 2953 SRLACFIERRKHQNDVRPIPNVKSYIVNR 2981


>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
          Length = 1289

 Score = 27.3 bits (59), Expect = 7.6
 Identities = 13/29 (44%), Positives = 19/29 (65%), Gaps = 1/29 (3%)

Query: 77   SRRACFILKMDHQN-IPPLNNLQWYIYEK 104
            SR ACFI +  HQN + P+ N++ YI  +
Sbjct: 1256 SRLACFIERRKHQNDVRPIPNVKSYIVNR 1284


>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
          Length = 2048

 Score = 26.9 bits (58), Expect = 9.9
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 27  ISPSNNGGNVQETVTIDNEKNTAIINIHAGSCSS 60
           I+P N   N+     I ++K++ I NI+ GS SS
Sbjct: 795 IAPRNESNNLASDTFITHKKSSFIKNINQGSSSS 828


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,885,176
Number of Sequences: 37866
Number of extensions: 277053
Number of successful extensions: 536
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 530
Number of HSP's gapped (non-prelim): 14
length of query: 184
length of database: 18,247,518
effective HSP length: 96
effective length of query: 88
effective length of database: 14,612,382
effective search space: 1285889616
effective search space used: 1285889616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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