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Search of human proteins with 58197562
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
(291 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 590 e-169
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 478 e-135
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 478 e-135
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 216 2e-56
gi|13259541 uncoupling protein 2 [Homo sapiens] 201 8e-52
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 196 2e-50
gi|11225256 uncoupling protein 1 [Homo sapiens] 172 3e-43
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 164 1e-40
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 159 4e-39
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic... 146 2e-35
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 123 2e-28
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 109 2e-24
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 105 4e-23
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 105 5e-23
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 104 1e-22
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 103 2e-22
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 101 9e-22
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 100 3e-21
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 100 3e-21
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 100 3e-21
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 100 3e-21
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 100 3e-21
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 100 3e-21
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 99 6e-21
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 98 7e-21
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 98 7e-21
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 94 1e-19
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 94 1e-19
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 94 1e-19
gi|41462412 solute carrier family 25, member 35 [Homo sapiens] 94 1e-19
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 590 bits (1520), Expect = e-169
Identities = 291/291 (100%), Positives = 291/291 (100%)
Query: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG
Sbjct: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
Query: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS
Sbjct: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
Query: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL
Sbjct: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
Query: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS 240
PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS
Sbjct: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS 240
Query: 241 GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL
Sbjct: 241 GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 478 bits (1231), Expect = e-135
Identities = 234/291 (80%), Positives = 262/291 (90%), Gaps = 1/291 (0%)
Query: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
MS LNWKPFVYGGLASI AE GTFP+DLTKTRLQ+QGQ+ DA+FKEI+YRGM HAL RI
Sbjct: 36 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRIC 95
Query: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
+EEG+ ALYSGIAPA+LRQASYGTIKIG YQSLKRLF+ER EDETL IN+ICG++SGVIS
Sbjct: 96 KEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVIS 155
Query: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
STIANPTDVLKIRMQAQ + QG MIG+F++IYQQEGTRGLW+GV TAQRAAIVVGVEL
Sbjct: 156 STIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVEL 215
Query: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS 240
PVYDITKKHLILSG+MGDT+ THF+SSFTCGLAGALASNPVDVVRTRMMNQR + G
Sbjct: 216 PVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAI-VGHVD 274
Query: 241 GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
Y GT+D +L+ WK+EGFFALYKGFWPNWLRLGPWNIIFF+TYEQLK+L +
Sbjct: 275 LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 478 bits (1231), Expect = e-135
Identities = 234/291 (80%), Positives = 262/291 (90%), Gaps = 1/291 (0%)
Query: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
MS LNWKPFVYGGLASI AE GTFP+DLTKTRLQ+QGQ+ DA+FKEI+YRGM HAL RI
Sbjct: 33 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRIC 92
Query: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
+EEG+ ALYSGIAPA+LRQASYGTIKIG YQSLKRLF+ER EDETL IN+ICG++SGVIS
Sbjct: 93 KEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVIS 152
Query: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
STIANPTDVLKIRMQAQ + QG MIG+F++IYQQEGTRGLW+GV TAQRAAIVVGVEL
Sbjct: 153 STIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVEL 212
Query: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS 240
PVYDITKKHLILSG+MGDT+ THF+SSFTCGLAGALASNPVDVVRTRMMNQR + G
Sbjct: 213 PVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAI-VGHVD 271
Query: 241 GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
Y GT+D +L+ WK+EGFFALYKGFWPNWLRLGPWNIIFF+TYEQLK+L +
Sbjct: 272 LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 322
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 216 bits (549), Expect = 2e-56
Identities = 115/295 (38%), Positives = 177/295 (60%), Gaps = 14/295 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQT-----NDAKFKEIRYRGMLHALVRIGREE 63
F+ G A+ AE TFP+DLTKTRLQ+QG+ D + YRGM+ + I EE
Sbjct: 23 FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82
Query: 64 GLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPI--NVICGILSGVISS 121
G L+ G+ PA+ R Y ++ TY+ L+ + + EDE P+ +VI G+++GVI
Sbjct: 83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVIGQ 142
Query: 122 TIANPTDVLKIRMQAQSNT-IQG------GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAI 174
+ANPTD++K++MQ + ++G G+ F I + G RGLW G QRAA+
Sbjct: 143 FLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAAL 202
Query: 175 VVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVL 234
V +L YD K +L+L+ + D + TH LSS GL ++ P DV+++R+MNQ
Sbjct: 203 VNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQPRD 262
Query: 235 RDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+ GR Y + DCL+Q + EGF +LYKGF P+WLR+ PW+++F++TYE+++++
Sbjct: 263 KQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREM 317
Score = 75.5 bits (184), Expect = 5e-14
Identities = 47/166 (28%), Positives = 86/166 (51%), Gaps = 8/166 (4%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
WK + G +A + + P DL K ++Q++G+ + K +R+RG+ HA +I E G+
Sbjct: 128 WKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGK-RKLEGKPLRFRGVHHAFAKILAEGGI 186
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKR-LFIERPEDETLPINVICGILSGVISSTIA 124
+ L++G P + R A + TY ++K L + P ++ + + + + SG+++S +
Sbjct: 187 RGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILG 246
Query: 125 NPTDVLKIRMQAQSNTIQG-GMIGN-----FMNIYQQEGTRGLWKG 164
P DV+K R+ Q QG G++ + Q EG L+KG
Sbjct: 247 TPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKG 292
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 201 bits (510), Expect = 8e-52
Identities = 109/286 (38%), Positives = 166/286 (58%), Gaps = 12/286 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDA--KFKEIRYRGMLHALVRIGREEGLK 66
F+ G A+ A+ TFP+D K RLQIQG++ +YRG++ ++ + R EG +
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPR 76
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANP 126
+LY+G+ + RQ S+ +++IG Y S+K+ + + E ++ ++ G +G ++ +A P
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQP 136
Query: 127 TDVLKIRMQAQSNTIQGGMIGNFMNIY----QQEGTRGLWKGVSLTAQRAAIVVGVELPV 182
TDV+K+R QAQ+ G + +N Y ++EG RGLWKG S R AIV EL
Sbjct: 137 TDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVT 196
Query: 183 YDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGY 242
YD+ K L+ + LM D + HF S+F G + ++PVDVV+TR MN + Y
Sbjct: 197 YDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSAL------GQY 250
Query: 243 TGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
+ C L + EG A YKGF P++LRLG WN++ FVTYEQLK+
Sbjct: 251 SSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 196 bits (498), Expect = 2e-50
Identities = 110/289 (38%), Positives = 166/289 (57%), Gaps = 15/289 (5%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKE-IRYRGMLHALVRIGREEGLKA 67
F+ G A+ A+ TFP+D K RLQIQG+ + ++YRG+L ++ + R EG +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 68 LYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-LPINVICGILSGVISSTIANP 126
Y+G+ + RQ S+ +I+IG Y S+K+++ + D + L ++ G +G ++ T A P
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Query: 127 TDVLKIRMQA-------QSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVE 179
TDV+K+R QA +S+ G + + I ++EG RGLWKG R AIV E
Sbjct: 137 TDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAE 196
Query: 180 LPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRC 239
+ YDI K+ L+ L+ D HF+S+F G + ++PVDVV+TR MN
Sbjct: 197 VVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP------ 250
Query: 240 SGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Y LDC+++ EG A YKGF P++LRLG WN++ FVTYEQLK+
Sbjct: 251 GQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Score = 39.3 bits (90), Expect = 0.004
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
FV A A P+D+ KTR +Y L ++++ +EG A
Sbjct: 221 FVSAFGAGFCATVVASPVDVVKTRYMNSPPG--------QYFSPLDCMIKMVAQEGPTAF 272
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIE 99
Y G P+ LR S+ + TY+ LKR ++
Sbjct: 273 YKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 172 bits (436), Expect = 3e-43
Identities = 97/283 (34%), Positives = 155/283 (54%), Gaps = 16/283 (5%)
Query: 13 GLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGI 72
G+A+ A+ TFP+D K RLQ+QG+ + IRY+G+L + + + EG LYSG+
Sbjct: 21 GIAACLADVITFPLDTAKVRLQVQGECPTSSV--IRYKGVLGTITAVVKTEGRMKLYSGL 78
Query: 73 APAMLRQASYGTIKIGTYQSLKRLFIERPEDE-TLPINVICGILSGVISSTIANPTDVLK 131
+ RQ S +++IG Y +++ E +L ++ G+ +G ++ I PT+V+K
Sbjct: 79 PAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVK 138
Query: 132 IRMQAQSNTIQG------GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
+R+QAQS+ + G G + I EG GLWKG + R+ I+ EL YD+
Sbjct: 139 VRLQAQSH-LHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDL 197
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGT 245
K+ + + ++ D V H +S+ G S+PVDVV+TR +N Y
Sbjct: 198 MKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPP------GQYKSV 251
Query: 246 LDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
+C ++ + NEG A +KG P++LRLG WN+I FV +EQLK+
Sbjct: 252 PNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKR 294
Score = 66.2 bits (160), Expect = 3e-11
Identities = 49/190 (25%), Positives = 83/190 (43%), Gaps = 7/190 (3%)
Query: 105 TLPINVICGILSGVISSTIANPTDVLKIRMQAQ-----SNTIQ-GGMIGNFMNIYQQEGT 158
TL + + ++ ++ I P D K+R+Q Q S+ I+ G++G + + EG
Sbjct: 12 TLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGR 71
Query: 159 RGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALAS 218
L+ G+ QR + + +YD ++ L ++ + L+ T G
Sbjct: 72 MKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIG 131
Query: 219 NPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNII 278
P +VV+ R+ Q L G YTGT + EG L+KG PN +R N
Sbjct: 132 QPTEVVKVRLQAQSHLH-GIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCT 190
Query: 279 FFVTYEQLKK 288
VTY+ +K+
Sbjct: 191 ELVTYDLMKE 200
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 164 bits (414), Expect = 1e-40
Identities = 102/287 (35%), Positives = 154/287 (53%), Gaps = 13/287 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F++GGLA + A P+DL K R+Q+ G+ AK +E Y+ HAL I + EGL+ +
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGE--GAKTRE--YKTSFHALTSILKAEGLRGI 80
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSL-KRLFIERPEDETLPINVICGILSGVISSTIANPT 127
Y+G++ +LRQA+Y T ++G Y L +RL + + G+ +G + + P
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPA 140
Query: 128 DVLKIRMQAQSNTIQGGMIG--NFMN----IYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181
+V IRM A G N N I ++EG LW+G T RA +V +L
Sbjct: 141 EVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLA 200
Query: 182 VYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
Y +K+ L+ SG D + HF +S GL AS PVD+ +TR+ N R++ DG+
Sbjct: 201 SYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMI-DGK-PE 258
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Y LD L + + EGFF+L+KGF P + RLGP ++ F+ EQ+ K
Sbjct: 259 YKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNK 305
Score = 57.4 bits (137), Expect = 1e-08
Identities = 45/196 (22%), Positives = 76/196 (38%), Gaps = 10/196 (5%)
Query: 100 RPEDETLPINVICGILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNF-------MNI 152
+P + + G L+G+ ++ P D++K RMQ +G + +I
Sbjct: 15 KPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSG---EGAKTREYKTSFHALTSI 71
Query: 153 YQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGL 212
+ EG RG++ G+S R A L +Y + + L + + T G
Sbjct: 72 LKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGA 131
Query: 213 AGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRL 272
GA P +V RM L + GY + L++ + EG L++G P R
Sbjct: 132 TGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARA 191
Query: 273 GPWNIIFFVTYEQLKK 288
N +Y Q K+
Sbjct: 192 VVVNAAQLASYSQSKQ 207
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 159 bits (401), Expect = 4e-39
Identities = 94/265 (35%), Positives = 145/265 (54%), Gaps = 15/265 (5%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKE-IRYRGMLHALVRIGREEGLKA 67
F+ G A+ A+ TFP+D K RLQIQG+ + ++YRG+L ++ + R EG +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 68 LYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-LPINVICGILSGVISSTIANP 126
Y+G+ + RQ S+ +I+IG Y S+K+++ + D + L ++ G +G ++ T A P
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Query: 127 TDVLKIRMQA-------QSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVE 179
TDV+K+R QA +S+ G + + I ++EG RGLWKG R AIV E
Sbjct: 137 TDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAE 196
Query: 180 LPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRC 239
+ YDI K+ L+ L+ D HF+S+F G + ++PVDVV+TR MN
Sbjct: 197 VVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP------ 250
Query: 240 SGYTGTLDCLLQTWKNEGFFALYKG 264
Y LDC+++ EG A YKG
Sbjct: 251 GQYFSPLDCMIKMVAQEGPTAFYKG 275
Score = 65.9 bits (159), Expect = 4e-11
Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 12/201 (5%)
Query: 100 RPED--ETLPINVICGILSGVISSTIANPTDVLKIRMQAQ--SNTIQG-------GMIGN 148
+P D T+ + + + + + P D K+R+Q Q + +Q G++G
Sbjct: 5 KPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGT 64
Query: 149 FMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSF 208
+ + + EG + G+ QR + + +YD K+ G ++ T L+
Sbjct: 65 ILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGC 124
Query: 209 TCGLAGALASNPVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLLQTWKNEGFFALYKGFWP 267
T G + P DVV+ R L R Y+GT+D + EG L+KG P
Sbjct: 125 TTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLP 184
Query: 268 NWLRLGPWNIIFFVTYEQLKK 288
N +R N VTY+ LK+
Sbjct: 185 NIMRNAIVNCAEVVTYDILKE 205
>gi|20149598 solute carrier family 25 (mitochondrial carrier;
dicarboxylate transporter), member 10 [Homo sapiens]
Length = 287
Score = 146 bits (369), Expect = 2e-35
Identities = 90/286 (31%), Positives = 149/286 (52%), Gaps = 26/286 (9%)
Query: 11 YGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYS 70
+GGLAS A C T P+DL K LQ Q + ++R GM +R+ R +G+ ALYS
Sbjct: 12 FGGLASCGAACCTHPLDLLKVHLQTQQEV------KLRMTGMA---LRVVRTDGILALYS 62
Query: 71 GIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPIN--VICGILSGVISSTIANPTD 128
G++ ++ RQ +Y + Y++++ + + LP + V+ G +SG+ + P D
Sbjct: 63 GLSASLCRQMTYSLTRFAIYETVRDR-VAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPAD 121
Query: 129 VLKIRMQAQSNTIQGGM------IGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPV 182
++ +RMQ QG + + ++EG R L+ G ++ + R A+V +L
Sbjct: 122 LVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSC 181
Query: 183 YDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGY 242
YD K+ ++ +G + D ++THF++SF G P+DV++TR+MN + Y
Sbjct: 182 YDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSK-------GEY 234
Query: 243 TGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
G C ++T K G A YKG P +RL P ++ FV EQL+K
Sbjct: 235 QGVFHCAVETAK-LGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRK 279
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 123 bits (309), Expect = 2e-28
Identities = 83/291 (28%), Positives = 137/291 (47%), Gaps = 17/291 (5%)
Query: 10 VYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALY 69
V G A A T P+++ KTRLQ+QG+ Y G + ++ + R +GL L
Sbjct: 11 VLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQ 70
Query: 70 SGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDV 129
G+A +L Q ++ Y + + + T V+ G ++G + + + +P +
Sbjct: 71 KGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGT----VVAGAVAGALGAFVGSPAYL 126
Query: 130 LKIRMQAQSNTIQGGMIGNFMN----------IYQQEGTRGLWKGVSLTAQRAAIVVGVE 179
+K ++QAQ T+ +G+ N I++Q+G GLW+GV R + +
Sbjct: 127 IKTQLQAQ--TVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQ 184
Query: 180 LPVYDITKKHLILSG-LMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGR 238
L + K + L D+ +A + P DVV TR+ NQ V GR
Sbjct: 185 LATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGR 244
Query: 239 CSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
Y G DC+++ W+ EG ALYKG P +LRLGP I+ + +++L+KL
Sbjct: 245 GQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKL 295
Score = 45.4 bits (106), Expect = 6e-05
Identities = 40/174 (22%), Positives = 77/174 (44%), Gaps = 19/174 (10%)
Query: 104 ETLP--INVICGILSGVISSTIANPTDVLKIRMQAQSNTIQG---------GMIGNFMNI 152
ET+P ++++ G + ++ NP +V+K R+Q Q +Q G I + +
Sbjct: 2 ETVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGE-LQARGTYPRPYHGFIASVAAV 60
Query: 153 YQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGL 212
+ +G GL KG++ ++ GV Y + + L+ G TV ++ G
Sbjct: 61 ARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQ-AGLTQQPGGTV----VAGAVAGA 115
Query: 213 AGALASNPVDVVRTRMMNQRV--LRDGRCSGYTGTLDCLLQTWKNEGFFALYKG 264
GA +P +++T++ Q V + G + L L W+ +G L++G
Sbjct: 116 LGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQG 169
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 109 bits (273), Expect = 2e-24
Identities = 82/292 (28%), Positives = 136/292 (46%), Gaps = 15/292 (5%)
Query: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
++ + WK V G +A + GT P+D RL++ Q + +K + G L ++V G
Sbjct: 181 LTGMWWKQLVAGAVAGAVSRTGTAPLD----RLKVFMQVHASKTNRLNILGGLRSMVLEG 236
Query: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
G+++L+ G +L+ A IK Y+ +KR + + E + + G L+G +
Sbjct: 237 ---GIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATA 293
Query: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
TI P +VLK R+ + G++ I ++EG R ++G G++L
Sbjct: 294 QTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
Query: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRD 236
VY+ T K+ L D+ L CG G +AS P+ +VRTRM Q +
Sbjct: 354 AVYE-TLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEG 412
Query: 237 GRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
G G L +L EG LY+G PN++++ P I +V YE +K+
Sbjct: 413 GPQLSMLGLLRHIL---SQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 87.8 bits (216), Expect = 1e-17
Identities = 58/190 (30%), Positives = 99/190 (52%), Gaps = 17/190 (8%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
FV G LA TA+ +P+++ KTRL ++ + +Y+G+L RI EG +A
Sbjct: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLR--------RTGQYKGLLDCARRILEREGPRAF 334
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN--- 125
Y G P +L Y I + Y++LK ++++ ++ ++ + G ISST
Sbjct: 335 YRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIAS 394
Query: 126 -PTDVLKIRMQAQSNTIQGG----MIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
P +++ RMQAQ++ I+GG M+G +I QEG RGL++G++ + V +
Sbjct: 395 YPLALVRTRMQAQAS-IEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISY 453
Query: 181 PVYDITKKHL 190
VY+ K+ L
Sbjct: 454 VVYENMKQAL 463
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 105 bits (263), Expect = 4e-23
Identities = 85/297 (28%), Positives = 139/297 (46%), Gaps = 23/297 (7%)
Query: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
K F+ GG+A+ ++ PI+ K LQ+Q + + +Y+G++ +VRI +E+G+
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADK-QYKGIVDCIVRIPKEQGVL 68
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-----LPINVICGILSGVISS 121
+ + G ++R + K++F+ + T N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSL 128
Query: 122 TIANPTDVLKIRMQA---QSNTIQG--GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
P D + R+ A +S T + G+ + I + +G RGL++G S++ Q I
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYR 188
Query: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSF----TCGLAGALASNPVDVVRTRMMNQR 232
VYD K G++ D TH + S+ T + S P D VR RMM Q
Sbjct: 189 AAYFGVYDTAK------GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQS 242
Query: 233 VLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
R G YTGT+DC + +++EG A +KG W N LR G V Y++LKK+
Sbjct: 243 G-RKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDELKKV 297
Score = 30.8 bits (68), Expect = 1.5
Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 211 GLAGALASN---PVDVVRTRMMNQRVLRD-GRCSGYTGTLDCLLQTWKNEGFFALYKGFW 266
G+A A++ P++ V+ + Q + Y G +DC+++ K +G + ++G
Sbjct: 16 GIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNL 75
Query: 267 PNWLRLGPWNIIFFVTYEQLKKLDL 291
N +R P + F ++ K++ L
Sbjct: 76 ANVIRYFPTQALNFAFKDKYKQIFL 100
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 105 bits (262), Expect = 5e-23
Identities = 82/296 (27%), Positives = 134/296 (45%), Gaps = 23/296 (7%)
Query: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
K F+ GG+A+ ++ PI+ K LQ+Q + + +Y+G++ +VRI +E+G+
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK-QYKGIIDCVVRIPKEQGVL 68
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-----LPINVICGILSGVISS 121
+ + G ++R + K++F+ + T N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
Query: 122 TIANPTDVLKIRMQAQSNTIQG-----GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
P D + R+ A G+ + IY+ +G +GL++G +++ Q I
Sbjct: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
Query: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSF----TCGLAGALASNPVDVVRTRMMNQR 232
+YD K G++ D TH + S+ T L S P D VR RMM Q
Sbjct: 189 AAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
Query: 233 VLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
R G YTGTLDC + ++EG A +KG W N LR G V Y+++KK
Sbjct: 243 G-RKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Score = 30.0 bits (66), Expect = 2.5
Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 211 GLAGALASN---PVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLLQTWKNEGFFALYKGFW 266
G+A A++ P++ V+ + Q + Y G +DC+++ K +G + ++G
Sbjct: 16 GVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNL 75
Query: 267 PNWLRLGPWNIIFFVTYEQLKKLDL 291
N +R P + F ++ K++ L
Sbjct: 76 ANVIRYFPTQALNFAFKDKYKQIFL 100
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 104 bits (259), Expect = 1e-22
Identities = 79/281 (28%), Positives = 127/281 (45%), Gaps = 8/281 (2%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F G +A +PIDL KTR+Q Q + + + E+ Y+ ++ R EG L
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQ-RGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTD 128
Y G+ P ++ A IK+ ++ F R LP V+ G +G NP +
Sbjct: 389 YRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLE 448
Query: 129 VLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKK 188
++KIR+Q G + + +N+ + G GL+KG R + PVY K
Sbjct: 449 IVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK- 506
Query: 189 HLILSGLMGDTVYTHFLSS-FTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLD 247
L+L+ G + L++ G+ A P DV++TR+ Q R G+ + Y+G +D
Sbjct: 507 -LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTT-YSGVID 562
Query: 248 CLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
C + + EG A +KG R P + VTYE L++
Sbjct: 563 CFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 21/187 (11%)
Query: 113 GILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFM---------NIYQQEGTRGLWK 163
G ++G + +T P D++K RMQ Q + G ++G M + + EG GL++
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGS--GSVVGELMYKNSFDCFKKVLRYEGFFGLYR 390
Query: 164 GVSLTAQRAAIVVGVELPVYDITK-KHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVD 222
G+ A ++L V D + K G + + L+ G + + +NP++
Sbjct: 391 GLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSV--PLPAEVLAGGCAGGSQVIFTNPLE 448
Query: 223 VVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVT 282
+V+ R+ + TG L ++ G F LYKG +LR P++ I+F
Sbjct: 449 IVKIRLQVAGEIT-------TGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPV 501
Query: 283 YEQLKKL 289
Y K L
Sbjct: 502 YAHCKLL 508
Score = 45.1 bits (105), Expect = 8e-05
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
G +A + A P D+ KTRLQ+ A+ + Y G++ +I REEG A + G
Sbjct: 525 GAMAGVPAASLVTPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPSAFWKG 579
Query: 72 IAPAMLRQASYGTIKIGTYQSLKRLF 97
A + R + + + TY+ L+R F
Sbjct: 580 TAARVFRSSPQFGVTLVTYELLQRWF 605
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 103 bits (257), Expect = 2e-22
Identities = 81/285 (28%), Positives = 129/285 (45%), Gaps = 13/285 (4%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
WK + G +A + GT P+D K +Q+ + + +L L + +E G
Sbjct: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN-------FTNLLGGLQSMVQEGGF 145
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK ++ K F ++ G L+ IS T+ N
Sbjct: 146 RSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLIN 205
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK R+ + G++ I Q+EGTR L++G +L VY++
Sbjct: 206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
Query: 186 TKKHLILSGL-MGDTVYTHFLSSFTCG-LAGALASNPVDVVRTRMMNQRVLRDGRCSGYT 243
+ + SG MGD LSS T G +AS P+ +VRTRM Q + +G
Sbjct: 266 LQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV-EGSNPTMR 324
Query: 244 GTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
G L +L +G+ LY+G P L++ P I +V YE +KK
Sbjct: 325 GVLQRIL---AQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 68.2 bits (165), Expect = 8e-12
Identities = 54/187 (28%), Positives = 90/187 (48%), Gaps = 19/187 (10%)
Query: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
G LA ++ P+++ KTRL ++ + +Y+G+L +I + EG +ALY G
Sbjct: 193 GSLAVAISQTLINPMEVLKTRLTLR--------RTGQYKGLLDCARQILQREGTRALYRG 244
Query: 72 IAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN-----P 126
P ML Y + Y+ L+ +++ D P ++ LS V ST P
Sbjct: 245 YLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVS--LSSVTLSTTCGQMASYP 302
Query: 127 TDVLKIRMQAQSNTIQGG---MIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVY 183
+++ RMQAQ +T++G M G I Q+G GL++G++ T + G+ VY
Sbjct: 303 LTLVRTRMQAQ-DTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVY 361
Query: 184 DITKKHL 190
+ KK L
Sbjct: 362 EAMKKTL 368
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 101 bits (251), Expect = 9e-22
Identities = 83/296 (28%), Positives = 132/296 (44%), Gaps = 23/296 (7%)
Query: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
K F+ GG+A+ ++ PI+ K LQ+Q + E +Y+G++ +VRI +E+G
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFL 68
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLF---IERPED--ETLPINVICGILSGVISS 121
+ + G ++R + K+LF ++R + N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
Query: 122 TIANPTDVLKIRMQAQSNTIQG-----GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
P D + R+ A G+ + I++ +G RGL++G +++ Q I
Sbjct: 129 CFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYR 188
Query: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLA----GALASNPVDVVRTRMMNQR 232
VYD K G++ D H S+ + L S P D VR RMM Q
Sbjct: 189 AAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS 242
Query: 233 VLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
R G YTGT+DC + K+EG A +KG W N LR G V Y+++KK
Sbjct: 243 G-RKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Score = 37.7 bits (86), Expect = 0.012
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 196 MGDTVYTHFLSSFTCGLAGALASN----PVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLL 250
MGD ++ FL F G A S P++ V+ + Q + Y G +DC++
Sbjct: 1 MGDHAWS-FLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVV 59
Query: 251 QTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
+ K +GF + ++G N +R P + F ++ K+L L
Sbjct: 60 RIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL 100
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 239
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 299
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 300 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 358
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 359 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 418
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 419 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 239
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 270
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 273
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 333
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 334 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 392
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 393 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 452
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 453 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 273
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 304
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 207 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 259
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 260 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 319
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 320 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 378
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 379 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 438
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 439 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 207 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 259
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 260 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 290
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 239
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 299
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 300 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 358
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 359 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 418
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 419 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 239
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 270
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 84 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 136
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 137 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 196
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 197 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 255
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 256 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 315
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 316 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 84 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 136
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 137 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 167
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 99.8 bits (247), Expect = 3e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 273
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 333
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 334 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 392
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 393 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 452
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 453 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 30.4 bits (67), Expect = 1.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 273
Query: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 274 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 304
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 98.6 bits (244), Expect = 6e-21
Identities = 77/282 (27%), Positives = 125/282 (44%), Gaps = 11/282 (3%)
Query: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
+ V GG A + C P+D+ KTR QIQ D Y+ ++ + I + EGL
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPN----SYKSLVDSFRMIFQMEGLF 70
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANP 126
Y GI P +L + +K T++ K+L L I G+ SG+ + + NP
Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTF-AIAGLGSGLTEAIVVNP 129
Query: 127 TDVLKIRMQAQSNTI--QGGMIGNFMNIYQQEG--TRGLWKGVSLTAQRAAIVVGVELPV 182
+V+K+ +QA NT Q +G I ++EG +GL KG++ T R + V
Sbjct: 130 FEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGF 189
Query: 183 YDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGY 242
Y K + ++ + F G ++ + P DV ++R+ + + G Y
Sbjct: 190 YYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPV-PGEIK-Y 247
Query: 243 TGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYE 284
+ ++ EG ALYKG P +RLGP + + YE
Sbjct: 248 RTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
Query: 209 TCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPN 268
+ GL +P+DVV+TR QR D + Y +D ++ EG F YKG P
Sbjct: 22 SAGLVEICLMHPLDVVKTRFQIQRCATDP--NSYKSLVDSFRMIFQMEGLFGFYKGILPP 79
Query: 269 WLRLGPWNIIFFVTYEQLKKL 289
L P + F T+EQ KKL
Sbjct: 80 ILAETPKRAVKFFTFEQYKKL 100
Score = 48.5 bits (114), Expect = 7e-06
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 12/186 (6%)
Query: 110 VICGILSGVISSTIANPTDVLKIRMQAQSNTIQGG----MIGNFMNIYQQEGTRGLWKGV 165
++ G +G++ + +P DV+K R Q Q ++ +F I+Q EG G +KG+
Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGI 76
Query: 166 SLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVR 225
V+ ++ KK +L + T ++ GL A+ NP +VV+
Sbjct: 77 LPPILAETPKRAVKFFTFEQYKK--LLGYVSLSPALTFAIAGLGSGLTEAIVVNPFEVVK 134
Query: 226 TRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFF--ALYKGFWPNWLRLGPWNIIFFVTY 283
+ R + T+ Q K EG+ L KG R G +N+++F Y
Sbjct: 135 VGLQANR----NTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFY 190
Query: 284 EQLKKL 289
+K +
Sbjct: 191 YNVKNM 196
Score = 45.4 bits (106), Expect = 6e-05
Identities = 51/187 (27%), Positives = 77/187 (41%), Gaps = 16/187 (8%)
Query: 9 FVYGGLAS-ITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREE-GLK 66
F GL S +T P ++ K LQ T + + Y + I +E GL+
Sbjct: 112 FAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQI-----IKKEGWGLQ 166
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPI--NVICGILSGVISSTIA 124
L G+ + R + + G Y ++K + I +D L G+LSG I+S I
Sbjct: 167 GLNKGLTATLGRHGVFNMVYFGFYYNVKNM-IPVNKDPILEFWRKFGIGLLSGTIASVIN 225
Query: 125 NPTDVLKIRMQAQSNTIQGGM-----IGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVE 179
P DV K R+Q + G + +YQ+EG L+KG+ R V
Sbjct: 226 IPFDVAKSRIQGPQ-PVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVM 284
Query: 180 LPVYDIT 186
L VY+ T
Sbjct: 285 LLVYEYT 291
Score = 45.4 bits (106), Expect = 6e-05
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ F G L+ A P D+ K+R+Q EI+YR + + +EEG+
Sbjct: 208 WRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPG----EIKYRTCFKTMATVYQEEGI 263
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQ 91
ALY G+ P ++R G + + Y+
Sbjct: 264 LALYKGLLPKIMRLGPGGAVMLLVYE 289
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 98.2 bits (243), Expect = 7e-21
Identities = 73/287 (25%), Positives = 124/287 (43%), Gaps = 15/287 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ + GG+A + T P+D K +Q+ G +D +R M+ +E G+
Sbjct: 195 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGI 247
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +++ A +K Y+ K+L E + I G ++G + T
Sbjct: 248 RSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIY 307
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +V+K R+ G+ I + EG +KG G++L VY++
Sbjct: 308 PMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
K + L D+V + CG G LAS P+ +VRTRM Q +L
Sbjct: 368 LKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 426
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
G ++ EG LY+G PN++++ P I +V YE +K+
Sbjct: 427 MVGLFRRII---SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 83.6 bits (205), Expect = 2e-16
Identities = 55/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F+ G +A TA+ +P+++ KTRL + G+T +Y G+ +I + EGL A
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAV-GKTG-------QYSGIYDCAKKILKHEGLGAF 343
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVI----CGILSGVISSTIA 124
Y G P +L Y I + Y+ LK +++ +++ V+ CG LS +
Sbjct: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403
Query: 125 NPTDVLKIRMQAQS---NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181
P +++ RMQAQ+ + Q M+G F I +EG GL++G++ + VG+
Sbjct: 404 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 463
Query: 182 VYDITKKHL 190
VY+ K+ L
Sbjct: 464 VYENMKQTL 472
Score = 28.9 bits (63), Expect = 5.6
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 211 GLAGALASN---PVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWP 267
G+AGA++ P+D ++ M G S Q K G +L++G
Sbjct: 202 GIAGAVSRTSTAPLDRLKIMMQVH-----GSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 256
Query: 268 NWLRLGPWNIIFFVTYEQLKKL 289
N +++ P + F YEQ KKL
Sbjct: 257 NVIKIAPETAVKFWAYEQYKKL 278
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 98.2 bits (243), Expect = 7e-21
Identities = 73/287 (25%), Positives = 124/287 (43%), Gaps = 15/287 (5%)
Query: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
W+ + GG+A + T P+D K +Q+ G +D +R M+ +E G+
Sbjct: 176 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGI 228
Query: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
++L+ G +++ A +K Y+ K+L E + I G ++G + T
Sbjct: 229 RSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIY 288
Query: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
P +V+K R+ G+ I + EG +KG G++L VY++
Sbjct: 289 PMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348
Query: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
K + L D+V + CG G LAS P+ +VRTRM Q +L
Sbjct: 349 LKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407
Query: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
G ++ EG LY+G PN++++ P I +V YE +K+
Sbjct: 408 MVGLFRRII---SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 83.6 bits (205), Expect = 2e-16
Identities = 55/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F+ G +A TA+ +P+++ KTRL + G+T +Y G+ +I + EGL A
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAV-GKTG-------QYSGIYDCAKKILKHEGLGAF 324
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVI----CGILSGVISSTIA 124
Y G P +L Y I + Y+ LK +++ +++ V+ CG LS +
Sbjct: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Query: 125 NPTDVLKIRMQAQS---NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181
P +++ RMQAQ+ + Q M+G F I +EG GL++G++ + VG+
Sbjct: 385 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 444
Query: 182 VYDITKKHL 190
VY+ K+ L
Sbjct: 445 VYENMKQTL 453
Score = 28.9 bits (63), Expect = 5.6
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 211 GLAGALASN---PVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWP 267
G+AGA++ P+D ++ M G S Q K G +L++G
Sbjct: 183 GIAGAVSRTSTAPLDRLKIMMQVH-----GSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 237
Query: 268 NWLRLGPWNIIFFVTYEQLKKL 289
N +++ P + F YEQ KKL
Sbjct: 238 NVIKIAPETAVKFWAYEQYKKL 259
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 94.4 bits (233), Expect = 1e-19
Identities = 80/300 (26%), Positives = 130/300 (43%), Gaps = 33/300 (11%)
Query: 7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLK 66
K + GG+A+ ++ PI+ K LQ+Q + E RY+GM+ LVRI RE+G
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQIS-PEARYKGMVDCLVRIPREQGFF 80
Query: 67 ALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-----LPINVICGILSGVISS 121
+ + G ++R + K+LF+ E N+ G +G S
Sbjct: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
Query: 122 TIANPTDVLKIRM-----QAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
+ P D + R+ + G+ M I + +G GL++G ++ Q +
Sbjct: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
Query: 177 GVELPVYDITKKHLILSGLMGDTVYTHFLSSF-------TCGLAGALASNPVDVVRTRMM 229
YD K GL+ T FL SF TC + S P D VR RMM
Sbjct: 201 ASYFGAYDTVK------GLLPKPKKTPFLVSFFIAQVVTTC---SGILSYPFDTVRRRMM 251
Query: 230 NQRVLRDGRCS-GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
++ G Y GTLDC ++ +++EG + ++G + N LR G + V Y+++K+
Sbjct: 252 ----MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGALVLVLYDKIKE 306
Score = 48.5 bits (114), Expect = 7e-06
Identities = 47/208 (22%), Positives = 92/208 (44%), Gaps = 18/208 (8%)
Query: 94 KRLFIERPEDETLPINVICGILSGVISSTIANPTDVLKIRMQAQSNTIQ-------GGMI 146
KRLF + + +++ G ++ +S T P + +K+ +Q Q+++ Q GM+
Sbjct: 12 KRLF----DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMV 67
Query: 147 GNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTH-FL 205
+ I +++G W+G R + D K L +SG+ + + FL
Sbjct: 68 DCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKD-KYKQLFMSGVNKEKQFWRWFL 126
Query: 206 SSFTCGLAGALAS----NPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFAL 261
++ G A S P+D RTR+ + + + G DC+++ K++G L
Sbjct: 127 ANLASGGAAGATSLCVVYPLDFARTRL-GVDIGKGPEERQFKGLGDCIMKIAKSDGIAGL 185
Query: 262 YKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
Y+GF + + + +F Y+ +K L
Sbjct: 186 YQGFGVSVQGIIVYRASYFGAYDTVKGL 213
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 94.0 bits (232), Expect = 1e-19
Identities = 74/283 (26%), Positives = 123/283 (43%), Gaps = 12/283 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F G +A +PIDL KTR+Q Q T E+ Y+ ++ R EG L
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF-VGELMYKNSFDCFKKVLRYEGFFGL 390
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTD 128
Y G+ P +L A IK+ ++ F+ + L ++ G +G NP +
Sbjct: 391 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 450
Query: 129 VLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKK 188
++KIR+Q G + + +++ + G G++KG R + P Y
Sbjct: 451 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY----A 505
Query: 189 HLILSGLMGD---TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGT 245
H+ S D + + L+ G+ A P DV++TR+ Q R G+ + Y+G
Sbjct: 506 HVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTT-YSGV 562
Query: 246 LDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
+DC + + EG AL+KG R P + +TYE L++
Sbjct: 563 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
Score = 45.8 bits (107), Expect = 4e-05
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Query: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
G +A + A P D+ KTRLQ+ A+ + Y G++ +I REEG KAL+ G
Sbjct: 527 GAIAGMPAASLVTPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKG 581
Query: 72 IAPAMLRQASYGTIKIGTYQSLKRLF 97
+ R + + + TY+ L+R F
Sbjct: 582 AGARVFRSSPQFGVTLLTYELLQRWF 607
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 94.0 bits (232), Expect = 1e-19
Identities = 74/283 (26%), Positives = 123/283 (43%), Gaps = 12/283 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F G +A +PIDL KTR+Q Q T E+ Y+ ++ R EG L
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF-VGELMYKNSFDCFKKVLRYEGFFGL 391
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTD 128
Y G+ P +L A IK+ ++ F+ + L ++ G +G NP +
Sbjct: 392 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 451
Query: 129 VLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKK 188
++KIR+Q G + + +++ + G G++KG R + P Y
Sbjct: 452 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY----A 506
Query: 189 HLILSGLMGD---TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGT 245
H+ S D + + L+ G+ A P DV++TR+ Q R G+ + Y+G
Sbjct: 507 HVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTT-YSGV 563
Query: 246 LDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
+DC + + EG AL+KG R P + +TYE L++
Sbjct: 564 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606
Score = 45.8 bits (107), Expect = 4e-05
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Query: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
G +A + A P D+ KTRLQ+ A+ + Y G++ +I REEG KAL+ G
Sbjct: 528 GAIAGMPAASLVTPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKG 582
Query: 72 IAPAMLRQASYGTIKIGTYQSLKRLF 97
+ R + + + TY+ L+R F
Sbjct: 583 AGARVFRSSPQFGVTLLTYELLQRWF 608
>gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
Length = 295
Score = 94.0 bits (232), Expect = 1e-19
Identities = 69/241 (28%), Positives = 114/241 (47%), Gaps = 11/241 (4%)
Query: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
F+ GLA+ A T P+++ KTR+Q+QG+ + YR + HA + IG+ +GL AL
Sbjct: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
Query: 69 YSGIAPAMLRQASYGTIKIGTYQSLKR-LFIERPEDETLPI-NVICGILSGVISSTIANP 126
G+APA+L Q I++GTY + ++ E P + G ++GV+ + + +P
Sbjct: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSP 122
Query: 127 TDVLKIRMQAQSNT--------IQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGV 178
++K +QAQ+ + GM I Q+ G GLW+G R +
Sbjct: 123 IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSST 182
Query: 179 ELPVYDITKKHLILSGLMGDTVY-THFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDG 237
+L + TK L + + +++ G+A LA P DV TR+ NQ G
Sbjct: 183 QLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQG 242
Query: 238 R 238
+
Sbjct: 243 K 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,851,138
Number of Sequences: 37866
Number of extensions: 379945
Number of successful extensions: 1431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 721
Number of HSP's gapped (non-prelim): 216
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.