Guide to the Human Genome
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Search of human proteins with 5803157

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo
sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]     639   0.0  
gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]    358   4e-99
gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]                  107   1e-23
gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]   103   1e-22
gi|68160945 sterol-C5-desaturase [Homo sapiens]                        81   1e-15
gi|68160941 sterol-C5-desaturase [Homo sapiens]                        81   1e-15
gi|51972212 transmembrane protein 195 [Homo sapiens]                   43   4e-04
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    29   4.3  
gi|205360949 fatty acid 2-hydroxylase [Homo sapiens]                   29   5.6  
gi|154759277 monocyte to macrophage differentiation-associated 2...    28   7.3  
gi|154759275 monocyte to macrophage differentiation-associated 2...    28   7.3  
gi|30581170 CC chemokine receptor 3 [Homo sapiens]                     28   7.3  
gi|4502637 CC chemokine receptor 3 [Homo sapiens]                      28   7.3  

>gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]
          Length = 293

 Score =  639 bits (1649), Expect = 0.0
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEA 60
           MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEA
Sbjct: 1   MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEA 60

Query: 61  LYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFT 120
           LYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFT
Sbjct: 61  LYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFT 120

Query: 121 EYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPF 180
           EYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPF
Sbjct: 121 EYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPF 180

Query: 181 GMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNL 240
           GMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNL
Sbjct: 181 GMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNL 240

Query: 241 IPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE 293
           IPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
Sbjct: 241 IPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE 293


>gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]
          Length = 162

 Score =  358 bits (918), Expect = 4e-99
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 132 MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLE 191
           MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLE
Sbjct: 1   MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLE 60

Query: 192 TLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHD 251
           TLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHD
Sbjct: 61  TLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHD 120

Query: 252 FHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE 293
           FHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
Sbjct: 121 FHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE 162


>gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]
          Length = 272

 Score =  107 bits (267), Expect = 1e-23
 Identities = 66/221 (29%), Positives = 105/221 (47%), Gaps = 13/221 (5%)

Query: 62  YFLFCLP----GFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTY 117
           Y  FCLP      L  ++P +++YKI  D   + +    C    L+ H     P+    +
Sbjct: 48  YVGFCLPFVVLDILCSWVPALRRYKIHPDFSPSAQQLLPCLGQTLYQHVMFVFPVTL-LH 106

Query: 118 YFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKR--IYKYIHKVHHE 175
           +      +P++    P    LL     C ++ D   +F+  LLHHK   +Y+  HKVHH+
Sbjct: 107 WARSPALLPHE---APELLLLLHHILFCLLLFDM-EFFVWHLLHHKVPWLYRTFHKVHHQ 162

Query: 176 FQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPL 235
             + F +  +Y    E   LG    + + LL  H +    +  + +  +++ HSGY+ P 
Sbjct: 163 NSSSFALATQYMSVWELFSLGFFDMMNVTLLGCHPLTTLTFHVVNIWLSVEDHSGYNFPW 222

Query: 236 NPLNLIPF--YAGSRHHDFHHMNFIGNYASTFTWWDRIFGT 274
           +   L+PF  Y G  HHD HH +F  N+A  FT WD+I GT
Sbjct: 223 STHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWDKILGT 263


>gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]
          Length = 333

 Score =  103 bits (258), Expect = 1e-22
 Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 13/205 (6%)

Query: 77  YMKKYKIQ--KDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPR 134
           ++ +Y+IQ  K++P       +  + +LFN   I  P++   Y F +++  P   E +P 
Sbjct: 109 FISRYRIQVGKNEPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRE-LPT 167

Query: 135 WYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLI 194
           +++ L       +IE+   Y+ HRLLHH   YK IHK HHE+ AP G+ + YAHP+E  +
Sbjct: 168 FHWFLLELAIFTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAV 227

Query: 195 LG-TGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFH 253
                  +G +++  H+  +  W ++ L+ T   H GY         +PF      HD+H
Sbjct: 228 SNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCGYH--------LPFLPSPEFHDYH 279

Query: 254 HMNFIGNYASTFTWWDRIFGTDSQY 278
           H+ F   Y       D + GTD+ +
Sbjct: 280 HLKFNQCY-GVLGVLDHLHGTDTMF 303


>gi|68160945 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/135 (33%), Positives = 70/135 (51%), Gaps = 2/135 (1%)

Query: 150 DTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDH 209
           D + Y++HR LHH+ +YK +HK HH ++ P    +   HP++  +    + I   +   H
Sbjct: 131 DMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLH 190

Query: 210 VILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWD 269
            ++  +   +  + TI +H G D  + P  L PF  GS HH  HHM F  NY   FT WD
Sbjct: 191 KVVYLSLYILVNIWTISIHDG-DFRV-PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWD 248

Query: 270 RIFGTDSQYNAYNEK 284
           RI G+    +++  K
Sbjct: 249 RIGGSFKNPSSFEGK 263


>gi|68160941 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/135 (33%), Positives = 70/135 (51%), Gaps = 2/135 (1%)

Query: 150 DTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDH 209
           D + Y++HR LHH+ +YK +HK HH ++ P    +   HP++  +    + I   +   H
Sbjct: 131 DMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLH 190

Query: 210 VILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWD 269
            ++  +   +  + TI +H G D  + P  L PF  GS HH  HHM F  NY   FT WD
Sbjct: 191 KVVYLSLYILVNIWTISIHDG-DFRV-PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWD 248

Query: 270 RIFGTDSQYNAYNEK 284
           RI G+    +++  K
Sbjct: 249 RIGGSFKNPSSFEGK 263


>gi|51972212 transmembrane protein 195 [Homo sapiens]
          Length = 445

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 42/166 (25%), Positives = 61/166 (36%), Gaps = 20/166 (12%)

Query: 123 FNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGM 182
           FN+P  W+    WY             D  +Y+ HR+ H   I    H+ HH  +  + +
Sbjct: 107 FNLP--WDSPWTWYSAFLGV-------DFGYYWFHRMAHEVNIMWAGHQTHHSSE-DYNL 156

Query: 183 EAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIP 242
                  +  +     F+  + L     +     +   LL    +H+     L PL LI 
Sbjct: 157 STALRQSVLQIYTSWIFYSPLALFIPPSVYA-VHLQFNLLYQFWIHTEVINNLGPLELI- 214

Query: 243 FYAGSRHHDFHHMN----FIGNYASTFTWWDRIFGTDSQYNAYNEK 284
                 HH  HH         NYA     WD+IFGT   + A NEK
Sbjct: 215 -LNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGT---FEAENEK 256


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 39   YMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCF 98
            YM  N   FQ  TW  ++     YF+  +   L   +  MK Y    D P  +E   KC 
Sbjct: 1452 YMPQNRQSFQYKTWTFVVSPPFEYFIMAMIA-LNTVVLMMKFY----DAPYEYELMLKCL 1506

Query: 99   KVLLFNHFCIQLPLICGTYYFTEYF 123
             ++  + F ++  L    +    YF
Sbjct: 1507 NIVFTSMFSMECVLKIIAFGVLNYF 1531


>gi|205360949 fatty acid 2-hydroxylase [Homo sapiens]
          Length = 372

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 13/28 (46%), Positives = 15/28 (53%)

Query: 147 VIEDTWHYFLHRLLHHKRIYKYIHKVHH 174
           V+ D  HY+LH    HK  Y Y  K HH
Sbjct: 309 VLYDMTHYYLHFGSPHKGSYLYSLKAHH 336


>gi|154759277 monocyte to macrophage differentiation-associated 2
           isoform 1 [Homo sapiens]
          Length = 270

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 14/127 (11%)

Query: 70  FLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDW 129
           F+   +P  K+Y+     P  +E+   C       H    +P I G+     YF    DW
Sbjct: 17  FMNHRVPAHKRYQ-----PTEYEHAANCA-----THAFWIIPSILGSSNL--YFLSDDDW 64

Query: 130 ERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHP 189
           E +  W + L  C G  V+   +H    +  H + +   +H +       F + A YA  
Sbjct: 65  ETISAWIYGLGLC-GLFVVSTVFHTISWKKSHLRMVEHCLH-MFDRMVIYFFIAASYAPW 122

Query: 190 LETLILG 196
           L    LG
Sbjct: 123 LNLRELG 129


>gi|154759275 monocyte to macrophage differentiation-associated 2
           isoform 2 [Homo sapiens]
          Length = 246

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 14/127 (11%)

Query: 70  FLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDW 129
           F+   +P  K+Y+     P  +E+   C       H    +P I G+     YF    DW
Sbjct: 17  FMNHRVPAHKRYQ-----PTEYEHAANCA-----THAFWIIPSILGSSNL--YFLSDDDW 64

Query: 130 ERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHP 189
           E +  W + L  C G  V+   +H    +  H + +   +H +       F + A YA  
Sbjct: 65  ETISAWIYGLGLC-GLFVVSTVFHTISWKKSHLRMVEHCLH-MFDRMVIYFFIAASYAPW 122

Query: 190 LETLILG 196
           L    LG
Sbjct: 123 LNLRELG 129


>gi|30581170 CC chemokine receptor 3 [Homo sapiens]
          Length = 355

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 6/72 (8%)

Query: 49  IATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCI 108
           I TWG  ++     F+F     LF+       Y      PE     W+ F  L    FC+
Sbjct: 155 IVTWGLAVLAALPEFIFYETEELFEETLCSALY------PEDTVYSWRHFHTLRMTIFCL 208

Query: 109 QLPLICGTYYFT 120
            LPL+     +T
Sbjct: 209 VLPLLVMAICYT 220


>gi|4502637 CC chemokine receptor 3 [Homo sapiens]
          Length = 355

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 6/72 (8%)

Query: 49  IATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCI 108
           I TWG  ++     F+F     LF+       Y      PE     W+ F  L    FC+
Sbjct: 155 IVTWGLAVLAALPEFIFYETEELFEETLCSALY------PEDTVYSWRHFHTLRMTIFCL 208

Query: 109 QLPLICGTYYFT 120
            LPL+     +T
Sbjct: 209 VLPLLVMAICYT 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.492 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,985,468
Number of Sequences: 37866
Number of extensions: 551158
Number of successful extensions: 1205
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 13
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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