Guide to the Human Genome
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Search of human proteins with 5803048

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803048 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein
retention receptor 1 [Homo sapiens]
         (212 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803048 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein ...   430   e-121
gi|5803050 KDEL receptor 2 isoform 1 [Homo sapiens]                   375   e-104
gi|6857802 KDEL receptor 3 isoform a [Homo sapiens]                   326   1e-89
gi|8051611 KDEL receptor 3 isoform b [Homo sapiens]                   307   4e-84
gi|154736713 KDEL receptor 2 isoform 2 [Homo sapiens]                 198   2e-51
gi|89062505 PREDICTED: similar to KDEL receptor [Homo sapiens]        191   3e-49
gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1 iso...    30   1.5  
gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1 is...    30   1.5  
gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1 is...    30   1.5  
gi|239745529 PREDICTED: hypothetical protein XP_002343479 [Homo ...    28   4.4  
gi|85797660 limkain b1 [Homo sapiens]                                  28   7.5  
gi|49619231 solute carrier family 37 member 1 [Homo sapiens]           28   7.5  
gi|223717983 solute carrier family 37 (glycerol-3-phosphate tran...    27   9.8  
gi|38093649 solute carrier family 37 (glycerol-3-phosphate trans...    27   9.8  
gi|68533260 chitinase 3-like 2 isoform c [Homo sapiens]                27   9.8  
gi|68533253 chitinase 3-like 2 isoform b [Homo sapiens]                27   9.8  
gi|68533255 chitinase 3-like 2 isoform a [Homo sapiens]                27   9.8  

>gi|5803048 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein
           retention receptor 1 [Homo sapiens]
          Length = 212

 Score =  430 bits (1106), Expect = e-121
 Identities = 212/212 (100%), Positives = 212/212 (100%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN
Sbjct: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
           TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW
Sbjct: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120

Query: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
           TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA
Sbjct: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180

Query: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212
           IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA
Sbjct: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212


>gi|5803050 KDEL receptor 2 isoform 1 [Homo sapiens]
          Length = 212

 Score =  375 bits (963), Expect = e-104
 Identities = 177/212 (83%), Positives = 199/212 (93%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           MN+FR  GDLSHL AI++LLLKIWK+RSCAGISGKSQ+LFA+VFT RYLDLFT++ISLYN
Sbjct: 1   MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
           T MKV+Y+ACS+ TV+LIY KFKATYDGNHDTFRVEFLVVP   L+FLVNHDF+PLEILW
Sbjct: 61  TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILW 120

Query: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
           TFSIYLESVAILPQLFM+SKTGEAETIT+HYLF LG+YR LYL NWIWR++FEGFFDLIA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIA 180

Query: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212
           +VAG+VQT+LYCDFFYLYITKVLKGKKLSLPA
Sbjct: 181 VVAGVVQTILYCDFFYLYITKVLKGKKLSLPA 212


>gi|6857802 KDEL receptor 3 isoform a [Homo sapiens]
          Length = 214

 Score =  326 bits (835), Expect = 1e-89
 Identities = 154/211 (72%), Positives = 184/211 (87%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           MN+FR LGDLSHLLA+ILLL KIW+S+ C GISGKSQ+LFA+VFT RYLDLFTN+IS+YN
Sbjct: 1   MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
           T MKVV++ C++ TV++IY KF+ T+D  +DTFR+EFL+VP   L+FL N+ FT LEILW
Sbjct: 61  TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW 120

Query: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
           TFSIYLESVAILPQLFM+SKTGEAETIT+HYLF LG+YR LYL NWI RY  E F+D IA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA 180

Query: 181 IVAGLVQTVLYCDFFYLYITKVLKGKKLSLP 211
           +V+G+VQT+ YCDFFYLY+TKVLKGKKLSLP
Sbjct: 181 VVSGVVQTIFYCDFFYLYVTKVLKGKKLSLP 211


>gi|8051611 KDEL receptor 3 isoform b [Homo sapiens]
          Length = 220

 Score =  307 bits (787), Expect = 4e-84
 Identities = 144/201 (71%), Positives = 174/201 (86%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           MN+FR LGDLSHLLA+ILLL KIW+S+ C GISGKSQ+LFA+VFT RYLDLFTN+IS+YN
Sbjct: 1   MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW 120
           T MKVV++ C++ TV++IY KF+ T+D  +DTFR+EFL+VP   L+FL N+ FT LEILW
Sbjct: 61  TVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW 120

Query: 121 TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA 180
           TFSIYLESVAILPQLFM+SKTGEAETIT+HYLF LG+YR LYL NWI RY  E F+D IA
Sbjct: 121 TFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIA 180

Query: 181 IVAGLVQTVLYCDFFYLYITK 201
           +V+G+VQT+ YCDFFYLY+TK
Sbjct: 181 VVSGVVQTIFYCDFFYLYVTK 201


>gi|154736713 KDEL receptor 2 isoform 2 [Homo sapiens]
          Length = 186

 Score =  198 bits (504), Expect = 2e-51
 Identities = 93/117 (79%), Positives = 107/117 (91%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           MN+FR  GDLSHL AI++LLLKIWK+RSCAGISGKSQ+LFA+VFT RYLDLFT++ISLYN
Sbjct: 1   MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLE 117
           T MKV+Y+ACS+ TV+LIY KFKATYDGNHDTFRVEFLVVP   L+FLVNHDF+PLE
Sbjct: 61  TSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLE 117


>gi|89062505 PREDICTED: similar to KDEL receptor [Homo sapiens]
          Length = 219

 Score =  191 bits (486), Expect = 3e-49
 Identities = 98/214 (45%), Positives = 144/214 (67%), Gaps = 9/214 (4%)

Query: 1   MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN 60
           M L R +GD+ HL AI++LL K+ + RS AGIS KS  LFA+VF  RY+D+  ++I +YN
Sbjct: 1   MALVRVVGDMLHLSAILILLSKMLRQRSAAGISLKSMELFAIVFCTRYIDVLFSFIGIYN 60

Query: 61  TCMKVVYIACSFTTVWLIYSK--FKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTP--- 115
           T MK+ +IA +    +L+  K  +KATYD  +DTFR+ +L+VP  +L+ L +   TP   
Sbjct: 61  TTMKIFFIASTLHICYLMKFKSPWKATYDRENDTFRIRYLIVPCVVLSILFHG--TPRRS 118

Query: 116 --LEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFE 173
             +E+ WTFS YLE+VAILPQ+F++  T   + +TSHYLF LG YR +Y+ +W  RY+  
Sbjct: 119 IVIELCWTFSQYLEAVAILPQIFLLEYTERYDALTSHYLFCLGAYRVVYMIHWAIRYYIY 178

Query: 174 GFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKK 207
                I++++G VQ++LY DFFY Y+ +VL+  K
Sbjct: 179 HKVRWISVLSGFVQSLLYVDFFYHYVVQVLRKAK 212


>gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform c [Homo sapiens]
          Length = 831

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 15/95 (15%)

Query: 8   GDLSHLLAIILLLLKIWKS-RSCAGISGKSQ-VLFAVVFTARYLDLFTNYISLYNTCMKV 65
           GD  H   I++ L  +W   R    +S K++  +F+ VF+ RY+ L     S+Y     +
Sbjct: 408 GDFGH--GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYT---GL 462

Query: 66  VYIAC------SFTTVWLIYSKFKATYDGNHDTFR 94
           +Y  C       F + W +   F  TY+   +T R
Sbjct: 463 IYNDCFSKSLNIFGSSWSVRPMF--TYNWTEETLR 495


>gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform b [Homo sapiens]
          Length = 837

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 15/95 (15%)

Query: 8   GDLSHLLAIILLLLKIWKS-RSCAGISGKSQ-VLFAVVFTARYLDLFTNYISLYNTCMKV 65
           GD  H   I++ L  +W   R    +S K++  +F+ VF+ RY+ L     S+Y     +
Sbjct: 408 GDFGH--GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYT---GL 462

Query: 66  VYIAC------SFTTVWLIYSKFKATYDGNHDTFR 94
           +Y  C       F + W +   F  TY+   +T R
Sbjct: 463 IYNDCFSKSLNIFGSSWSVRPMF--TYNWTEETLR 495


>gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform a [Homo sapiens]
          Length = 838

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 15/95 (15%)

Query: 8   GDLSHLLAIILLLLKIWKS-RSCAGISGKSQ-VLFAVVFTARYLDLFTNYISLYNTCMKV 65
           GD  H   I++ L  +W   R    +S K++  +F+ VF+ RY+ L     S+Y     +
Sbjct: 415 GDFGH--GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYT---GL 469

Query: 66  VYIAC------SFTTVWLIYSKFKATYDGNHDTFR 94
           +Y  C       F + W +   F  TY+   +T R
Sbjct: 470 IYNDCFSKSLNIFGSSWSVRPMF--TYNWTEETLR 502


>gi|239745529 PREDICTED: hypothetical protein XP_002343479 [Homo
          sapiens]
          Length = 138

 Score = 28.5 bits (62), Expect = 4.4
 Identities = 12/21 (57%), Positives = 17/21 (80%)

Query: 8  GDLSHLLAIILLLLKIWKSRS 28
          G LS +L+ ILLLL++W SR+
Sbjct: 40 GTLSQMLSAILLLLQLWDSRA 60


>gi|85797660 limkain b1 [Homo sapiens]
          Length = 1742

 Score = 27.7 bits (60), Expect = 7.5
 Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 6/56 (10%)

Query: 121  TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFF 176
            T +  L+S+  L ++F   K  E   +TS YLFA  V   L+       YH++  F
Sbjct: 1458 TLTELLKSLPYLVEVFTNDKMEECVKLTSLYLFAKNVRSLLH------TYHYQQIF 1507


>gi|49619231 solute carrier family 37 member 1 [Homo sapiens]
          Length = 533

 Score = 27.7 bits (60), Expect = 7.5
 Identities = 11/37 (29%), Positives = 20/37 (54%)

Query: 152 LFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQT 188
           + A G +  L+   + +  H  GF+ +  ++ GLVQT
Sbjct: 134 MLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQT 170


>gi|223717983 solute carrier family 37 (glycerol-3-phosphate
           transporter), member 2 isoform 2 [Homo sapiens]
          Length = 501

 Score = 27.3 bits (59), Expect = 9.8
 Identities = 11/33 (33%), Positives = 19/33 (57%)

Query: 156 GVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQT 188
           G++ +L+   + W  H   +F +I +  GLVQT
Sbjct: 126 GLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQT 158


>gi|38093649 solute carrier family 37 (glycerol-3-phosphate
           transporter), member 2 isoform 1 [Homo sapiens]
          Length = 505

 Score = 27.3 bits (59), Expect = 9.8
 Identities = 11/33 (33%), Positives = 19/33 (57%)

Query: 156 GVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQT 188
           G++ +L+   + W  H   +F +I +  GLVQT
Sbjct: 126 GLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQT 158


>gi|68533260 chitinase 3-like 2 isoform c [Homo sapiens]
          Length = 311

 Score = 27.3 bits (59), Expect = 9.8
 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 3/31 (9%)

Query: 92  TFRVEFLVVPTAILAFLVNHDFTPLEILWTF 122
           T R+EF+    +I+ FL NH+F  L++ W +
Sbjct: 40  TSRLEFI---NSIILFLRNHNFDGLDVSWIY 67


>gi|68533253 chitinase 3-like 2 isoform b [Homo sapiens]
          Length = 380

 Score = 27.3 bits (59), Expect = 9.8
 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 3/31 (9%)

Query: 92  TFRVEFLVVPTAILAFLVNHDFTPLEILWTF 122
           T R+EF+    +I+ FL NH+F  L++ W +
Sbjct: 109 TSRLEFI---NSIILFLRNHNFDGLDVSWIY 136


>gi|68533255 chitinase 3-like 2 isoform a [Homo sapiens]
          Length = 390

 Score = 27.3 bits (59), Expect = 9.8
 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 3/31 (9%)

Query: 92  TFRVEFLVVPTAILAFLVNHDFTPLEILWTF 122
           T R+EF+    +I+ FL NH+F  L++ W +
Sbjct: 119 TSRLEFI---NSIILFLRNHNFDGLDVSWIY 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.333    0.144    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,901,563
Number of Sequences: 37866
Number of extensions: 257525
Number of successful extensions: 568
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 555
Number of HSP's gapped (non-prelim): 17
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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