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Search of human proteins with 5802974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens] 518 e-147
gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens] 471 e-133
gi|5453549 peroxiredoxin 4 [Homo sapiens] 275 3e-74
gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens] 267 6e-72
gi|32455266 peroxiredoxin 1 [Homo sapiens] 264 5e-71
gi|32455264 peroxiredoxin 1 [Homo sapiens] 264 5e-71
gi|4505591 peroxiredoxin 1 [Homo sapiens] 264 5e-71
gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ... 176 2e-44
gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens] 118 6e-27
gi|4758638 peroxiredoxin 6 [Homo sapiens] 64 1e-10
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens] 37 0.022
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 30 1.6
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 28 6.0
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 28 6.0
gi|47078224 AT rich interactive domain 5A [Homo sapiens] 28 6.0
>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
Length = 256
Score = 518 bits (1334), Expect = e-147
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC 60
MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
Sbjct: 1 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC 60
Query: 61 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 120
HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
Sbjct: 61 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 120
Query: 121 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 180
EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
Sbjct: 121 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 180
Query: 181 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 240
LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
Sbjct: 181 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 240
Query: 241 KPSPAASKEYFQKVNQ 256
KPSPAASKEYFQKVNQ
Sbjct: 241 KPSPAASKEYFQKVNQ 256
>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
Length = 238
Score = 471 bits (1211), Expect = e-133
Identities = 238/256 (92%), Positives = 238/256 (92%), Gaps = 18/256 (7%)
Query: 1 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC 60
MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQA
Sbjct: 1 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQA--------- 51
Query: 61 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 120
PYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
Sbjct: 52 ---------PYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN 102
Query: 121 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 180
EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
Sbjct: 103 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG 162
Query: 181 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 240
LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
Sbjct: 163 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI 222
Query: 241 KPSPAASKEYFQKVNQ 256
KPSPAASKEYFQKVNQ
Sbjct: 223 KPSPAASKEYFQKVNQ 238
>gi|5453549 peroxiredoxin 4 [Homo sapiens]
Length = 271
Score = 275 bits (703), Expect = 3e-74
Identities = 127/191 (66%), Positives = 155/191 (81%)
Query: 65 VTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHD 124
+++ APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+ EF
Sbjct: 81 ISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRS 140
Query: 125 VNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALR 184
+N EVVA SVDS F+HLAWINTPR+ GGLG + I LLSDLT QIS+DYGV LE SG LR
Sbjct: 141 INTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLR 200
Query: 185 GLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSP 244
GLFIID G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGEVCPA W P S TI P P
Sbjct: 201 GLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDP 260
Query: 245 AASKEYFQKVN 255
A +YF K+N
Sbjct: 261 AGKLKYFDKLN 271
>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
Length = 198
Score = 267 bits (683), Expect = 6e-72
Identities = 125/187 (66%), Positives = 152/187 (81%)
Query: 69 APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 128
AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F + CE
Sbjct: 12 APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
Query: 129 VVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFI 188
V+ VSVDS F+HLAWINTPRK GGLG +NI LL+D+T+++S DYGVL G+A RGLFI
Sbjct: 72 VLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFI 131
Query: 189 IDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASK 248
ID GV++ ++VNDLPVGRSV+E LRLV+AFQY + HGEVCPA W P S TIKP+ SK
Sbjct: 132 IDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSK 191
Query: 249 EYFQKVN 255
EYF K N
Sbjct: 192 EYFSKHN 198
>gi|32455266 peroxiredoxin 1 [Homo sapiens]
Length = 199
Score = 264 bits (675), Expect = 5e-71
Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)
Query: 69 APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 127
AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF +NC
Sbjct: 12 APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71
Query: 128 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 187
+V+ SVDSHF HLAW+NTP+K GGLG MNI L+SD + I++DYGVL G++ RGLF
Sbjct: 72 QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131
Query: 188 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 247
IID G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191
Query: 248 KEYFQK 253
KEYF K
Sbjct: 192 KEYFSK 197
>gi|32455264 peroxiredoxin 1 [Homo sapiens]
Length = 199
Score = 264 bits (675), Expect = 5e-71
Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)
Query: 69 APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 127
AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF +NC
Sbjct: 12 APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71
Query: 128 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 187
+V+ SVDSHF HLAW+NTP+K GGLG MNI L+SD + I++DYGVL G++ RGLF
Sbjct: 72 QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131
Query: 188 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 247
IID G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191
Query: 248 KEYFQK 253
KEYF K
Sbjct: 192 KEYFSK 197
>gi|4505591 peroxiredoxin 1 [Homo sapiens]
Length = 199
Score = 264 bits (675), Expect = 5e-71
Identities = 122/186 (65%), Positives = 150/186 (80%), Gaps = 1/186 (0%)
Query: 69 APYFKGTAVV-NGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 127
AP FK TAV+ +G+FKD+SL D+KGKY+V FFYPLDFTFVCPTEI+AFSD+A EF +NC
Sbjct: 12 APNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNC 71
Query: 128 EVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLF 187
+V+ SVDSHF HLAW+NTP+K GGLG MNI L+SD + I++DYGVL G++ RGLF
Sbjct: 72 QVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLF 131
Query: 188 IIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAAS 247
IID G+++ ++VNDLPVGRSV+ETLRLV+AFQ+ + HGEVCPA W P S TIKP S
Sbjct: 132 IIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKS 191
Query: 248 KEYFQK 253
KEYF K
Sbjct: 192 KEYFSK 197
>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
sapiens]
Length = 233
Score = 176 bits (446), Expect = 2e-44
Identities = 88/170 (51%), Positives = 116/170 (68%), Gaps = 24/170 (14%)
Query: 65 VTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHD 124
+++ APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+ EF
Sbjct: 81 ISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRS 140
Query: 125 VNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALR 184
+N EVVA SVDS F+HLAW +S Y + L L+
Sbjct: 141 INTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLLLK 177
Query: 185 GLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCP-ANW 233
GLFIID G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGE P ++W
Sbjct: 178 GLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSW 227
>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
Length = 142
Score = 118 bits (295), Expect = 6e-27
Identities = 52/75 (69%), Positives = 64/75 (85%)
Query: 69 APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 128
AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F + CE
Sbjct: 12 APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
Query: 129 VVAVSVDSHFSHLAW 143
V+ VSVDS F+HLAW
Sbjct: 72 VLGVSVDSQFTHLAW 86
>gi|4758638 peroxiredoxin 6 [Homo sapiens]
Length = 224
Score = 64.3 bits (155), Expect = 1e-10
Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 69 APYFKGTAVVNGEFKDLSLDDFKG-KYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNC 127
AP F+ V + DF G + +LF +P DFT VC TE+ + A EF N
Sbjct: 11 APNFEANTTVGR----IRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNV 66
Query: 128 EVVAVSVDSHFSHLAW---INTPRKNGGLGHMNIALLSDLTKQISRDYGVL------LEG 178
+++A+S+DS HLAW IN + ++ D ++++ G+L +G
Sbjct: 67 KLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKG 126
Query: 179 SGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSP 238
+ R +F+ P+ +K + GR+ +E LR+V + Q P +W D
Sbjct: 127 MPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDW-KDGD 185
Query: 239 TIKPSPAASKEYFQKV 254
++ P +E +K+
Sbjct: 186 SVMVLPTIPEEEAKKL 201
>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
Length = 137
Score = 36.6 bits (83), Expect = 0.022
Identities = 18/48 (37%), Positives = 27/48 (56%)
Query: 96 VLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAW 143
+LF +P D VC E+ + A EF N +++A++ DS HLAW
Sbjct: 34 ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAW 81
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 30.4 bits (67), Expect = 1.6
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Query: 112 IVAFSDKANEFHDV--NCEVVAVSV---DSHFSHLAWINTPRKNGG 152
+V+ S +NE H V NC+ + + +FS++ W N P+K GG
Sbjct: 14 VVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGG 59
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 28.5 bits (62), Expect = 6.0
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)
Query: 204 PVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAA 246
PV SVEE + GE PA P+SPT P PAA
Sbjct: 719 PVPPSVEE----------IPVPGEAVPAPTPPESPTPHPPPAA 751
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 28.5 bits (62), Expect = 6.0
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)
Query: 204 PVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAA 246
PV SVEE + GE PA P+SPT P PAA
Sbjct: 720 PVPPSVEE----------IPVPGEAVPAPTPPESPTPHPPPAA 752
>gi|47078224 AT rich interactive domain 5A [Homo sapiens]
Length = 594
Score = 28.5 bits (62), Expect = 6.0
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
Query: 17 VSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQH-APYF 72
+ A P ATA P A G + + +L SS+ HAP VT + AP+F
Sbjct: 531 IPAFPAHFLATAGPSPMAAGLMHFPPTSFDSALRHRLCPASSAWHAPPVTTYAAPHF 587
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,387,972
Number of Sequences: 37866
Number of extensions: 396436
Number of successful extensions: 906
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 892
Number of HSP's gapped (non-prelim): 15
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.