Guide to the Human Genome
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Search of human proteins with 56682945

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56682945 spindlin-like protein 2 [Homo sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56682949 spindlin-like protein 2 [Homo sapiens]                    528   e-150
gi|56682947 spindlin-like protein 2 [Homo sapiens]                    528   e-150
gi|56682945 spindlin-like protein 2 [Homo sapiens]                    528   e-150
gi|117606320 spindlin family, member 2 [Homo sapiens]                 527   e-150
gi|112293285 spindlin [Homo sapiens]                                  416   e-116
gi|115527078 spindlin family, member 3 [Homo sapiens]                 411   e-115
gi|108796661 spindlin family, member 4 [Homo sapiens]                 341   3e-94
gi|111955326 MLX interacting protein [Homo sapiens]                    33   0.25 
gi|118918411 zinc finger protein 777 [Homo sapiens]                    31   1.2  
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]    30   2.7  
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    30   2.7  
gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific ...    29   4.6  
gi|189491742 ataxin 7 isoform b [Homo sapiens]                         28   6.1  
gi|4506797 ataxin 7 isoform a [Homo sapiens]                           28   6.1  
gi|12232397 SMAD specific E3 ubiquitin protein ligase 2 [Homo sa...    28   7.9  

>gi|56682949 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  528 bits (1361), Expect = e-150
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60
           MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE
Sbjct: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60

Query: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120
           GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS
Sbjct: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120

Query: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180
           DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD
Sbjct: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180

Query: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240
           YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF
Sbjct: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240

Query: 241 IKFDDDFHIYVYDLVKKS 258
           IKFDDDFHIYVYDLVKKS
Sbjct: 241 IKFDDDFHIYVYDLVKKS 258


>gi|56682947 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  528 bits (1361), Expect = e-150
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60
           MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE
Sbjct: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60

Query: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120
           GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS
Sbjct: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120

Query: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180
           DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD
Sbjct: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180

Query: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240
           YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF
Sbjct: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240

Query: 241 IKFDDDFHIYVYDLVKKS 258
           IKFDDDFHIYVYDLVKKS
Sbjct: 241 IKFDDDFHIYVYDLVKKS 258


>gi|56682945 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  528 bits (1361), Expect = e-150
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60
           MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE
Sbjct: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60

Query: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120
           GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS
Sbjct: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120

Query: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180
           DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD
Sbjct: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180

Query: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240
           YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF
Sbjct: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240

Query: 241 IKFDDDFHIYVYDLVKKS 258
           IKFDDDFHIYVYDLVKKS
Sbjct: 241 IKFDDDFHIYVYDLVKKS 258


>gi|117606320 spindlin family, member 2 [Homo sapiens]
          Length = 258

 Score =  527 bits (1357), Expect = e-150
 Identities = 257/258 (99%), Positives = 257/258 (99%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60
           MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE
Sbjct: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60

Query: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120
           GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS
Sbjct: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120

Query: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180
           DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD
Sbjct: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180

Query: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240
           YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVE KPSVYF
Sbjct: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVETKPSVYF 240

Query: 241 IKFDDDFHIYVYDLVKKS 258
           IKFDDDFHIYVYDLVKKS
Sbjct: 241 IKFDDDFHIYVYDLVKKS 258


>gi|112293285 spindlin [Homo sapiens]
          Length = 262

 Score =  416 bits (1068), Expect = e-116
 Identities = 202/263 (76%), Positives = 226/263 (85%), Gaps = 6/263 (2%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRG-----RPSSQPRRNIVGCRIS 55
           MKTP  +   GQ++RA AG A  SANM KK+ S KK R      +P SQPRRNIVGCRI 
Sbjct: 1   MKTPFGK-TPGQRSRADAGHAGVSANMMKKRTSHKKHRSSVGPSKPVSQPRRNIVGCRIQ 59

Query: 56  HGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVA 115
           HGWKEG+ P+TQWKGTVLDQVP+NPSLYL+KYDG DCVYGLEL++DERV +L++L DRVA
Sbjct: 60  HGWKEGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVA 119

Query: 116 SSHISDANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMY 175
           +S ISDA+LA+T+IGKAVEHMFE E GSKDEWRGMVLA+AP+M  WFYITYEKDPVLYMY
Sbjct: 120 TSRISDAHLADTMIGKAVEHMFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMY 179

Query: 176 QLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAK 235
           QLLDDYKEGDLRIMP+S++SPP EREPG VVD L+GK VEY KEDGSKR GMVIHQVEAK
Sbjct: 180 QLLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAK 239

Query: 236 PSVYFIKFDDDFHIYVYDLVKKS 258
           PSVYFIKFDDDFHIYVYDLVK S
Sbjct: 240 PSVYFIKFDDDFHIYVYDLVKTS 262


>gi|115527078 spindlin family, member 3 [Homo sapiens]
          Length = 258

 Score =  411 bits (1057), Expect = e-115
 Identities = 192/258 (74%), Positives = 220/258 (85%)

Query: 1   MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKE 60
           MKTP  + A GQ++R  AG  + S  M K+K + KK R RP+SQPR NIVGCRI HGWK+
Sbjct: 1   MKTPFGKAAAGQRSRTGAGHGSVSVTMIKRKAAHKKHRSRPTSQPRGNIVGCRIQHGWKD 60

Query: 61  GDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHIS 120
           GDEP+TQWKGTVLDQVP+NPSLYL+KYDG DCVYGLELHRDERV SL++L +RVASS IS
Sbjct: 61  GDEPLTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHRDERVSSLEVLPNRVASSRIS 120

Query: 121 DANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDD 180
           D +LA  ++GKAVEH+FE E GSK+EWRGMVLAQAP+M  WFYITYEKDPVLYMYQLLDD
Sbjct: 121 DTHLAEIMVGKAVEHIFETEEGSKNEWRGMVLAQAPVMNTWFYITYEKDPVLYMYQLLDD 180

Query: 181 YKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYF 240
           YK+GDLRI+ +S++SP  EREPG V+D L+GK VEY K+DGSKR GMVIHQVEAKPSVYF
Sbjct: 181 YKDGDLRILQDSNDSPLAEREPGEVIDSLVGKQVEYAKDDGSKRTGMVIHQVEAKPSVYF 240

Query: 241 IKFDDDFHIYVYDLVKKS 258
           IKFDDDFHIYVYDLVK S
Sbjct: 241 IKFDDDFHIYVYDLVKTS 258


>gi|108796661 spindlin family, member 4 [Homo sapiens]
          Length = 249

 Score =  341 bits (875), Expect = 3e-94
 Identities = 162/234 (69%), Positives = 198/234 (84%), Gaps = 2/234 (0%)

Query: 24  SANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLY 83
           SA + KK+ + +KQR +P+   RRNIVGCRI HGWKEG+EP+ QWKGTVL+QV + P+LY
Sbjct: 15  SAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLY 74

Query: 84  LVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGS 143
           ++KYDG D VYGLELHRD+RVL+L+IL +RV +  I D+ LA+++IGKAVEH+FEGEHG+
Sbjct: 75  IIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGT 133

Query: 144 KDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPT-EREP 202
           KDEW+GMVLA+AP+M  WFYITYEKDPVLYMY LLDDYK+GDLRI+P+S+   PT E+EP
Sbjct: 134 KDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEP 193

Query: 203 GGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVK 256
           G VVD L+GK VE+ K+DGSKR G+ IHQV AKPSVYFIKFDDD HIYVY LVK
Sbjct: 194 GEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVK 247


>gi|111955326 MLX interacting protein [Homo sapiens]
          Length = 919

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 113 RVASSHIS-DANLANTI-------IGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWF-- 162
           + +S H+S DA+L            GK V   ++   G K +WR  +     I +AW+  
Sbjct: 114 KTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQ 173

Query: 163 YITYEKDPVLYMYQLLDDYKEGDLRIMPES 192
           Y+   K+PV +    LD   + D    PE+
Sbjct: 174 YLEKRKNPVCHFVTPLDGSVDVDEHRRPEA 203


>gi|118918411 zinc finger protein 777 [Homo sapiens]
          Length = 831

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 135 HMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPES-- 192
           H  E E G+  EW+  +     +M+  +      D  +    L+   + G+   M E   
Sbjct: 293 HFSEQEWGNLSEWQKELYKN--VMRGNYESLVSMDYAISKPDLMSQMERGERPTMQEQED 350

Query: 193 SESPPTEREPGGVVDGLIGKHVEYTKEDGSKRI 225
           SE   T  +P    DG++ K    T ++GS+ +
Sbjct: 351 SEEGETPTDPSAAHDGIVIKIEVQTNDEGSESL 383


>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
          Length = 1462

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 23/87 (26%)

Query: 159  KAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTK 218
            K WF I   K  VLY Y   +D           + ES P           L+G  +   K
Sbjct: 1382 KLWFVI---KGKVLYTYMASED---------KVALESMP-----------LLGFTIAPEK 1418

Query: 219  EDGSKRIGMVIHQVEAKPSVYFIKFDD 245
            E+GS  +G + H    K   Y  K +D
Sbjct: 1419 EEGSSEVGPIFHLYHKKTLFYSFKAED 1445


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
            sapiens]
          Length = 1710

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 16/43 (37%), Positives = 28/43 (65%), Gaps = 2/43 (4%)

Query: 9    AEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVG 51
            +EG+++R+   R +GS + +  +  + K+RGRP + PR NI G
Sbjct: 1085 SEGRRSRSR--RYSGSDSDSISEGKRPKKRGRPRTIPRENIKG 1125


>gi|226371750 terminal uridylyl transferase 1, U6 snRNA-specific
           [Homo sapiens]
          Length = 912

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 14/35 (40%), Positives = 21/35 (60%)

Query: 177 LLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIG 211
           LL+D +EGDL    E +E+P  E+  G  +  L+G
Sbjct: 349 LLEDREEGDLGKASELAETPKEEKAEGAAMLELVG 383


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 13/42 (30%), Positives = 23/42 (54%)

Query: 6  AQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRR 47
          A +  G+  RAAA     +A   +++  Q++Q+  P  QP+R
Sbjct: 6  ADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQR 47


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 13/42 (30%), Positives = 23/42 (54%)

Query: 6  AQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRR 47
          A +  G+  RAAA     +A   +++  Q++Q+  P  QP+R
Sbjct: 6  ADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQR 47


>gi|12232397 SMAD specific E3 ubiquitin protein ligase 2 [Homo
           sapiens]
          Length = 748

 Score = 28.1 bits (61), Expect = 7.9
 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 1/55 (1%)

Query: 82  LYLVKYDGIDCVYGLELHRDERVLSLKILSD-RVASSHISDANLANTIIGKAVEH 135
           LYL+ ++ ++  YGL  +  + + +L+I  D  V   H+S  +    I+G AV H
Sbjct: 442 LYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,262,885
Number of Sequences: 37866
Number of extensions: 469777
Number of successful extensions: 1373
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1316
Number of HSP's gapped (non-prelim): 16
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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