Search of human proteins with 56237018

Search of human proteins with 56237018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56237018 testis and skeletal muscle-specific dual
specificity phosphatase isoform 6 [Homo sapiens]
         (198 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56237018 testis and skeletal muscle-specific dual specificity...   396   e-111
gi|56117822 testis and skeletal muscle-specific dual specificity...   396   e-111
gi|56117820 testis and skeletal muscle-specific dual specificity...   396   e-111
gi|51491914 dual specificity phosphatase and pro isomerase domai...   181   4e-46
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]            167   7e-42
gi|56117818 muscle-restricted dual specificity phosphatase isofo...   151   4e-37
gi|122937243 dual specificity phosphatase 27 [Homo sapiens]           149   2e-36
gi|4758208 dual specificity phosphatase 3 [Homo sapiens]              130   6e-31
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     80   9e-16
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    80   9e-16
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              77   1e-14
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               76   2e-14
gi|225703077 dual specificity phosphatase 21 [Homo sapiens]            74   1e-13
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             73   2e-13
gi|239582767 slingshot homolog 3 [Homo sapiens]                        72   3e-13
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...    71   7e-13
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               70   9e-13
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              70   2e-12
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    65   4e-11
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              65   5e-11
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]               64   1e-10
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    63   2e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    63   2e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    63   2e-10
gi|75750526 dual specificity phosphatase 28 [Homo sapiens]             62   2e-10
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]             61   7e-10
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             60   9e-10
gi|37674210 slingshot 2 [Homo sapiens]                                 60   1e-09
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]    59   3e-09
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    59   4e-09

>gi|56237018 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 6 [Homo sapiens]
          Length = 198

 Score =  396 bits (1018), Expect = e-111
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 60
           MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA
Sbjct: 1   MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 60

Query: 61  ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 120
           ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA
Sbjct: 61  ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 120

Query: 121 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 180
           RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF
Sbjct: 121 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 180

Query: 181 LRQLQVLDNRLGRETGRF 198
           LRQLQVLDNRLGRETGRF
Sbjct: 181 LRQLQVLDNRLGRETGRF 198


>gi|56117822 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 3 [Homo sapiens]
          Length = 291

 Score =  396 bits (1018), Expect = e-111
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 60
           MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA
Sbjct: 94  MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 153

Query: 61  ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 120
           ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA
Sbjct: 154 ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 213

Query: 121 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 180
           RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF
Sbjct: 214 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 273

Query: 181 LRQLQVLDNRLGRETGRF 198
           LRQLQVLDNRLGRETGRF
Sbjct: 274 LRQLQVLDNRLGRETGRF 291


>gi|56117820 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 2 [Homo sapiens]
          Length = 248

 Score =  396 bits (1018), Expect = e-111
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 60
           MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA
Sbjct: 51  MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 110

Query: 61  ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 120
           ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA
Sbjct: 111 ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 170

Query: 121 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 180
           RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF
Sbjct: 171 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 230

Query: 181 LRQLQVLDNRLGRETGRF 198
           LRQLQVLDNRLGRETGRF
Sbjct: 231 LRQLQVLDNRLGRETGRF 248



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 12 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71
          P++ G  +A+P   P++  L+ LL   +++  + +DEVWP+LF+GDA  +  K  L +  
Sbjct: 7  PELGGEDKATPC--PSILELEELLRAGKSSC-SRVDEVWPNLFIGDAMDSLQKQDLRRPK 63

Query: 72 ITHVVNAA 79
          I   V A+
Sbjct: 64 IHGAVQAS 71


>gi|51491914 dual specificity phosphatase and pro isomerase domain
           containing 1 [Homo sapiens]
          Length = 220

 Score =  181 bits (459), Expect = 4e-46
 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 1/186 (0%)

Query: 12  PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71
           PK+    +   Y  P    L+RL W + +    H++EVWP L++GD   A D+ +L + G
Sbjct: 22  PKMEEEGEEEDYCTPGAFELERLFW-KGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAG 80

Query: 72  ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 131
            THV+NAA G++ VDTG  +YR M ++Y+G+EADD P FDLSV+F P A +I  ALS   
Sbjct: 81  FTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDH 140

Query: 132 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191
            ++LVHC MG SRSATLVLA+LMI ++MTLV+AIQ V  +R + PN GFL+QL+ LD +L
Sbjct: 141 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200

Query: 192 GRETGR 197
            ++  R
Sbjct: 201 VQQRRR 206


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score =  167 bits (422), Expect = 7e-42
 Identities = 86/161 (53%), Positives = 116/161 (72%), Gaps = 3/161 (1%)

Query: 31  LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK 90
           L+RLL+  + A  NH DEVWP L+LGD   A ++ +L +LGITHV+NA+  +++    A 
Sbjct: 48  LERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA- 105

Query: 91  FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL 150
            Y G+ + Y G+EA D+P FD+S++F   A +I  ALS P G++LVHCA+GVSRSATLVL
Sbjct: 106 -YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVL 164

Query: 151 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191
           A+LM+  ++TLVEAI+ V+ HR I PN GFLRQL  LD RL
Sbjct: 165 AYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205


>gi|56117818 muscle-restricted dual specificity phosphatase isoform
           1 [Homo sapiens]
          Length = 188

 Score =  151 bits (381), Expect = 4e-37
 Identities = 83/180 (46%), Positives = 119/180 (66%), Gaps = 4/180 (2%)

Query: 12  PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71
           P++ G  +A+P   P++  L+ LL   +++  + +DEVWP+LF+GDA  A ++ +L +LG
Sbjct: 7   PELGGEDKATPC--PSILELEELLRAGKSSC-SRVDEVWPNLFIGDAATANNRFELWKLG 63

Query: 72  ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 131
           ITHV+NAA        G  FY G S+ Y G+ A D P FD+S YF   A +I  AL+ P 
Sbjct: 64  ITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPG 122

Query: 132 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191
            +VLVHC +GVSRSATLVLA+LM+ + ++L +A+ TV+ HR + PN GFL QL  LD +L
Sbjct: 123 AKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182


>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
          Length = 1158

 Score =  149 bits (376), Expect = 2e-36
 Identities = 80/175 (45%), Positives = 115/175 (65%), Gaps = 2/175 (1%)

Query: 21  SPYQPPTLASLQR-LLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAA 79
           S Y  P +  LQR L+  RQ A  N +DEVWP++F+ +   A +K +L +LGITH++NAA
Sbjct: 108 SLYNTPCVLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAA 167

Query: 80  AGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCA 139
            G   V TG +FY G+ ++Y G+E DD P  D+S +F   + ++  AL   +G+VLV   
Sbjct: 168 HGT-GVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSE 226

Query: 140 MGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE 194
           MG+SRSA LV+A+LMI  NM ++EA+ TV+  R I PN GFL+QL+ L+ +L  E
Sbjct: 227 MGISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEE 281


>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
          Length = 185

 Score =  130 bits (328), Expect = 6e-31
 Identities = 71/150 (47%), Positives = 99/150 (66%), Gaps = 2/150 (1%)

Query: 47  DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGK--FQVDTGAKFYRGMSLEYYGIEA 104
           +EV P +++G+A  A+D  KL +LGITHV+NAA G+    V+T A FY+   + Y GI+A
Sbjct: 31  NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90

Query: 105 DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEA 164
           +D   F+LS YF   A +I  AL+   GRVLVHC  G SRS TLV+A+LM+ + M +  A
Sbjct: 91  NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150

Query: 165 IQTVQAHRNICPNSGFLRQLQVLDNRLGRE 194
           +  V+ +R I PN GFL QL  L++RL +E
Sbjct: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 9/145 (6%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P L+LG AY A  +  L  LGIT ++N ++           + G   +Y  I  +DN
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDC------PNHFEG-HYQYKCIPVEDN 250

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              D+S +F+    YI A     +GRVLVHC  G+SRSAT+ LA+LM+ + + L EA + 
Sbjct: 251 HKADISSWFMEAIEYIDAVKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309

Query: 168 VQAHRN-ICPNSGFLRQLQVLDNRL 191
           V+  R+ I PN  F+ QL   ++++
Sbjct: 310 VKQRRSIISPNFSFMGQLLQFESQV 334


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 9/145 (6%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P L+LG AY A  +  L  LGIT ++N ++           + G   +Y  I  +DN
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDC------PNHFEG-HYQYKCIPVEDN 159

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              D+S +F+    YI A     +GRVLVHC  G+SRSAT+ LA+LM+ + + L EA + 
Sbjct: 160 HKADISSWFMEAIEYIDAVKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 218

Query: 168 VQAHRN-ICPNSGFLRQLQVLDNRL 191
           V+  R+ I PN  F+ QL   ++++
Sbjct: 219 VKQRRSIISPNFSFMGQLLQFESQV 243


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 58/152 (38%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 46  IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 105
           I ++  SLFLG    A ++  L   GIT +VNA     ++      +     EY  +   
Sbjct: 27  IAQITSSLFLGRGSVASNRHLLQARGITCIVNAT---IEIPN----FNWPQFEYVKVPLA 79

Query: 106 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 165
           D P   + +YF  VA  I + +S   G  LVHCA GVSRSATL +A+LM   N+ L+EA 
Sbjct: 80  DMPHAPIGLYFDTVADKIHS-VSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138

Query: 166 QTVQAHRNIC-PNSGFLRQLQVLDNRL-GRET 195
             V+A R +  PN GF RQL   + +L G+ T
Sbjct: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKST 170


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 57/155 (36%), Positives = 78/155 (50%), Gaps = 14/155 (9%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P L+LG AY A  K  L  LGIT ++N +A           + G   +Y  I  +DN
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANC------PNHFEG-HYQYKSIPVEDN 228

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              D+S +F     +I +  +   GRV VHC  G+SRSAT+ LA+LM    + L EA + 
Sbjct: 229 HKADISSWFNEAIDFIDSIKNAG-GRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287

Query: 168 VQAHRN-ICPNSGFLRQL-----QVLDNRLGRETG 196
           V+  R+ I PN  F+ QL     QVL      E G
Sbjct: 288 VKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAG 322


>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
          Length = 190

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)

Query: 39  QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLE 98
           Q  ++    ++  SLFL +  AA DK  L    IT +VNA+     V     F+ G  ++
Sbjct: 15  QQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-----FFEG--IQ 67

Query: 99  YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 158
           Y  +   D     L  +F P+A  I   + + QGR L+HC  GVSRSA+L LA+LM   +
Sbjct: 68  YIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS 126

Query: 159 MTLVEAIQTVQAHRNIC-PNSGFLRQL 184
           M+L++A    ++ R I  PN+GF  QL
Sbjct: 127 MSLLDAHTWTKSRRPIIRPNNGFWEQL 153


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)

Query: 42  TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG 101
           +++ + ++  SL++ +  AA +K  L    IT V+N +     V+     Y    ++Y  
Sbjct: 16  SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYE--DIQYMQ 68

Query: 102 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTL 161
           +   D+P   L  +F P+A +I + + + QGR L+HCA GVSRSA L LA+LM    M+L
Sbjct: 69  VPVADSPNSRLCDFFDPIADHIHS-VEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSL 127

Query: 162 VEAIQTVQAHRNIC-PNSGFLRQL 184
           ++A    ++ R I  PNSGF  QL
Sbjct: 128 LDAHTWTKSCRPIIRPNSGFWEQL 151


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 58/157 (36%), Positives = 83/157 (52%), Gaps = 14/157 (8%)

Query: 32  QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 91
           Q LL V Q    +    ++P L+LG  + A +  +L +  +TH++N A    ++D    F
Sbjct: 318 QMLLLVAQR---DRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAR---EIDN---F 368

Query: 92  YRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQG-RVLVHCAMGVSRSATLVL 150
           Y      Y+ +   D     L  ++    R+I AA +  QG  VLVHC MGVSRSA  VL
Sbjct: 369 YPER-FTYHNVRLWDEESAQLLPHWKETHRFIEAARA--QGTHVLVHCKMGVSRSAATVL 425

Query: 151 AFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQV 186
           A+ M     +L +A++ VQ  R I  PN GFLRQLQ+
Sbjct: 426 AYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQI 462


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score = 70.9 bits (172), Expect = 7e-13
 Identities = 52/163 (31%), Positives = 79/163 (48%), Gaps = 11/163 (6%)

Query: 36  WVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGM 95
           +V+  ++   +  + P L LG   AA D   L +  +TH++N A G          Y+ +
Sbjct: 56  YVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSI 115

Query: 96  SLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMI 155
           S+        D P  ++  YF     +I  A     G VLVHC  GVSR+A +V+ FLM 
Sbjct: 116 SIL-------DLPETNILSYFPECFEFIEEAKR-KDGVVLVHCNAGVSRAAAIVIGFLMN 167

Query: 156 CENMTLVEAIQTVQ-AHRNICPNSGFLRQLQVLDNRLGRETGR 197
            E  +   A   V+ A  +ICPNSGF+ QL+      G+E+ +
Sbjct: 168 SEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQE--GKESNK 208


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 70.5 bits (171), Expect = 9e-13
 Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P LFLG    + D   L   GIT V+N +A      +    + G+   Y  I  +DN
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSA------SCPNHFEGL-FRYKSIPVEDN 227

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              ++S +F     +I    +   GRVLVHC  G+SRSAT+ LA+LM    + L EA   
Sbjct: 228 QMVEISAWFQEAIGFIDWVKN-SGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDF 286

Query: 168 VQAHRN-ICPNSGFLRQL 184
           V+  R  I PN  F+ QL
Sbjct: 287 VKQRRGVISPNFSFMGQL 304


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 10/143 (6%)

Query: 44  NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE 103
           N ++++ P L++G+   ARD  +L +  +TH+++        D+      G+  +Y  I 
Sbjct: 3   NGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVH------DSARPMLEGV--KYLCIP 54

Query: 104 ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVE 163
           A D+P  +L+ +F    ++I       +   LVHC  GVSRS TLV+A++M   +    +
Sbjct: 55  AADSPSQNLTRHFKESIKFIHECRLRGES-CLVHCLAGVSRSVTLVIAYIMTVTDFGWED 113

Query: 164 AIQTVQAHRNIC-PNSGFLRQLQ 185
           A+ TV+A R+   PN GF RQLQ
Sbjct: 114 ALHTVRAGRSCANPNVGFQRQLQ 136


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 29/191 (15%)

Query: 2   DSLQKQDLRRPKIHGAVQAS----PYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGD 57
           +SLQ Q+ R  ++ G   A+    P   PT   ++             +  + P LFLG+
Sbjct: 286 NSLQLQECR--EVGGGASAASSLLPQPIPTTPDIENA----------ELTPILPFLFLGN 333

Query: 58  AYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFY---RGMSLEYYGIEADDNPFFDLSV 114
              A+D   + +L I +V+N       V T    Y   +G+   Y  + A D+   +L  
Sbjct: 334 EQDAQDLDTMQRLNIGYVIN-------VTTHLPLYHYEKGL-FNYKRLPATDSNKQNLRQ 385

Query: 115 YFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRN- 173
           YF     +I  A    +G +L+HC  GVSRSAT+V+A+LM    MT+ +A + V+  R  
Sbjct: 386 YFEEAFEFIEEAHQCGKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444

Query: 174 ICPNSGFLRQL 184
           I PN  F+ QL
Sbjct: 445 ISPNLNFMGQL 455


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 9/138 (6%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P L+LG AY A     L  L IT ++N +    +            L Y  I  +D+
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA-------THLHYKWIPVEDS 233

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              D+S +F     +I        G+VLVHC  G+SRS T+ +A+LM  +   L EA   
Sbjct: 234 HTADISSHFQEAIDFIDCVRE-KGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292

Query: 168 VQAHRN-ICPNSGFLRQL 184
           ++  R+ + PN GF+ QL
Sbjct: 293 IKQRRSMVSPNFGFMGQL 310


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 7/148 (4%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           ++ P+L+LG A  + +   L +LGI +++N             F +     Y  I   D+
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNF-----FEKNGDFHYKQIPISDH 260

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              +LS +F     +I  ALS   G VLVHC  GVSRS T+ +A+LM   +++L +A   
Sbjct: 261 WSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDL 319

Query: 168 VQAHR-NICPNSGFLRQLQVLDNRLGRE 194
           V+  + NI PN  F+ QL   +  L  E
Sbjct: 320 VKRKKSNISPNFNFMGQLLDFERSLRLE 347


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)

Query: 46  IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 98
           + E+ P LFLG  Y++  KSKL  L   GITH++    N  A   + +    F       
Sbjct: 29  MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81

Query: 99  YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 158
           Y  ++  DNP  ++  +F     +I  +L +  G+VLVH   G+SRSA  V+A++M    
Sbjct: 82  YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140

Query: 159 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 185
           M   +A   VQ  R  I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)

Query: 46  IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 98
           + E+ P LFLG  Y++  KSKL  L   GITH++    N  A   + +    F       
Sbjct: 29  MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81

Query: 99  YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 158
           Y  ++  DNP  ++  +F     +I  +L +  G+VLVH   G+SRSA  V+A++M    
Sbjct: 82  YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140

Query: 159 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 185
           M   +A   VQ  R  I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)

Query: 46  IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 98
           + E+ P LFLG  Y++  KSKL  L   GITH++    N  A   + +    F       
Sbjct: 29  MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81

Query: 99  YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 158
           Y  ++  DNP  ++  +F     +I  +L +  G+VLVH   G+SRSA  V+A++M    
Sbjct: 82  YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140

Query: 159 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 185
           M   +A   VQ  R  I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168


>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
          Length = 176

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 49/144 (34%), Positives = 71/144 (49%), Gaps = 9/144 (6%)

Query: 49  VWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNP 108
           V PSLFLG A AA  + +L + G+T  VN +    +   G    R   +    +   D+P
Sbjct: 22  VAPSLFLGSARAAGAEEQLARAGVTLCVNVS----RQQPGP---RAPGVAELRVPVFDDP 74

Query: 109 FFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTV 168
             DL  +  P    + AA+    G  LV+C  G SRSA +  A+LM    ++L +A Q V
Sbjct: 75  AEDLLAHLEPTCAAMEAAVRAG-GACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMV 133

Query: 169 QAHRNIC-PNSGFLRQLQVLDNRL 191
           ++ R +  PN GF  QLQ  +  L
Sbjct: 134 KSARPVAEPNPGFWSQLQKYEEAL 157


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 47/146 (32%), Positives = 72/146 (49%), Gaps = 7/146 (4%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           ++ P L+LG A  + +   L + GI +++N        +    F  G    Y  I   D+
Sbjct: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTP-----NLPNAFEHGGEFTYKQIPISDH 301

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              +LS +F     +I  A S   G VLVHC  G+SRS T+ +A+LM   N++L +A   
Sbjct: 302 WSQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF 360

Query: 168 VQAHR-NICPNSGFLRQLQVLDNRLG 192
           V+  + NI PN  F+ QL   +  LG
Sbjct: 361 VKRKKSNISPNFNFMGQLLDFERTLG 386


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 60.5 bits (145), Expect = 9e-10
 Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 20/155 (12%)

Query: 49  VWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN- 107
           + P+L+LG      +K  + Q GI +V+NA+      +T  K        +  +  +D+ 
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNAS------NTCPKPDFIPESHFLRVPVNDSF 215

Query: 108 -----PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLV 162
                P+ D SV F+  A+          G VLVHC  G+SRSAT+ +A++M   +M+L 
Sbjct: 216 CEKILPWLDKSVDFIEKAK-------ASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLD 268

Query: 163 EAIQTVQAHR-NICPNSGFLRQLQVLDNRLGRETG 196
           EA + V+  R  I PN  FL QL   + ++  +TG
Sbjct: 269 EAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTG 303


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 9/139 (6%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           +++  +FLG  + A +   L   G+ +++N      ++D    F+ G+  EY+ I   D 
Sbjct: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTR---EIDN---FFPGV-FEYHNIRVYDE 362

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              DL  Y+    ++I  A      + LVHC MGVSRSA+ V+A+ M      L  A   
Sbjct: 363 EATDLLAYWNDTYKFISKAKK-HGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421

Query: 168 VQAHRNIC-PNSGFLRQLQ 185
           V+  R +  PN  F+RQL+
Sbjct: 422 VKERRTVTKPNPSFMRQLE 440


>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
          Length = 381

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 7/146 (4%)

Query: 48  EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
           E+ P L+LG A  + +   L + GI +++N       +     F      +Y  I   D+
Sbjct: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNL-----FENAGEFKYKQIPISDH 263

Query: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
              +LS +F     +I  A     G VLVHC  G+SRS T+ +A+LM   N+++ +A   
Sbjct: 264 WSQNLSQFFPEAISFIDEARGKNCG-VLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDI 322

Query: 168 VQAHR-NICPNSGFLRQLQVLDNRLG 192
           V+  + NI PN  F+ QL   +  LG
Sbjct: 323 VKMKKSNISPNFNFMGQLLDFERTLG 348


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 40/143 (27%), Positives = 68/143 (47%), Gaps = 10/143 (6%)

Query: 44  NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE 103
           N + +V P L+LG+   A+D  +L +  ITH+++       +           + Y  I 
Sbjct: 3   NGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLL--------QDITYLRIP 54

Query: 104 ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVE 163
             D P   +  +F     +I     +  G  LVHC  G+SRS T+V A++M    +   +
Sbjct: 55  VADTPEVPIKKHFKECINFIHCC-RLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRD 113

Query: 164 AIQTVQAHRNIC-PNSGFLRQLQ 185
            ++ ++A R I  PN GF +QL+
Sbjct: 114 VLEAIKATRPIANPNPGFRQQLE 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,611,387
Number of Sequences: 37866
Number of extensions: 241908
Number of successful extensions: 709
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 616
Number of HSP's gapped (non-prelim): 93
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.