Guide to the Human Genome
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Search of human proteins with 56121818

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56121818 dolichyl pyrophosphate Glc1Man9GlcNAc2
alpha-1,3-glucosyltransferase isoform a [Homo sapiens]
         (526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56121818 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glu...  1076   0.0  
gi|57165415 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glu...   917   0.0  
gi|38026892 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosy...   159   8e-39
gi|100913030 solute carrier family 26 member 2 [Homo sapiens]          33   0.84 
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    32   1.4  
gi|23503279 transmembrane protein 161B [Homo sapiens]                  32   1.9  
gi|46395496 G protein-coupled receptor for asthma susceptibility...    30   5.4  
gi|46391085 G protein-coupled receptor for asthma susceptibility...    30   5.4  
gi|94538339 signal-regulatory protein gamma isoform 3 precursor ...    29   9.2  
gi|94538337 signal-regulatory protein gamma isoform 2 precursor ...    29   9.2  
gi|94538335 signal-regulatory protein gamma isoform 1 precursor ...    29   9.2  

>gi|56121818 dolichyl pyrophosphate Glc1Man9GlcNAc2
           alpha-1,3-glucosyltransferase isoform a [Homo sapiens]
          Length = 526

 Score = 1076 bits (2783), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT 60
           MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT
Sbjct: 1   MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT 60

Query: 61  SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA 120
           SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA
Sbjct: 61  SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA 120

Query: 121 VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL 180
           VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL
Sbjct: 121 VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL 180

Query: 181 FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS 240
           FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS
Sbjct: 181 FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS 240

Query: 241 LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG 300
           LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG
Sbjct: 241 LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG 300

Query: 301 LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR 360
           LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR
Sbjct: 301 LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR 360

Query: 361 GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL 420
           GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL
Sbjct: 361 GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL 420

Query: 421 LFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPF 480
           LFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPF
Sbjct: 421 LFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPF 480

Query: 481 TSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ 526
           TSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ
Sbjct: 481 TSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ 526


>gi|57165415 dolichyl pyrophosphate Glc1Man9GlcNAc2
           alpha-1,3-glucosyltransferase isoform b [Homo sapiens]
          Length = 467

 Score =  917 bits (2370), Expect = 0.0
 Identities = 450/451 (99%), Positives = 451/451 (100%)

Query: 1   MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT 60
           MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT
Sbjct: 1   MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT 60

Query: 61  SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA 120
           SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA
Sbjct: 61  SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA 120

Query: 121 VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL 180
           VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL
Sbjct: 121 VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL 180

Query: 181 FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS 240
           FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS
Sbjct: 181 FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS 240

Query: 241 LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG 300
           LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG
Sbjct: 241 LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG 300

Query: 301 LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR 360
           LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR
Sbjct: 301 LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR 360

Query: 361 GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL 420
           GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL
Sbjct: 361 GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL 420

Query: 421 LFTAPELPIKILLMLLFTIYSISSLKTLFRK 451
           LFTAPELPIKILLMLLFTIYSISSLKTLFR+
Sbjct: 421 LFTAPELPIKILLMLLFTIYSISSLKTLFRR 451


>gi|38026892 dolichyl pyrophosphate Man9GlcNAc2
           alpha-1,3-glucosyltransferase [Homo sapiens]
          Length = 507

 Score =  159 bits (401), Expect = 8e-39
 Identities = 143/523 (27%), Positives = 239/523 (45%), Gaps = 86/523 (16%)

Query: 36  DFEVHRNWLAITHSLPISQWYYEATSE----WTLDYPPFFAWFEYILSHVAKYFDQEMLN 91
           D+E  R+W  IT +LP+ QWY+ ++      W LDYPP  A+   + ++VAK+ + + + 
Sbjct: 37  DYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIA 96

Query: 92  VH-NLNYSSSRTLLFQRFSVIFMDVL-FVYAVRECCKCIDGKKVGKELTEKPKFILSVLL 149
           +H +  Y S    LF R +V+  D+L ++ AV   C C+      KE++ K K   ++ +
Sbjct: 97  LHTSRGYESQAHKLFMRTTVLIADLLIYIPAVVLYCCCL------KEISTKKKIANALCI 150

Query: 150 LWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAY 209
           L   GL+++D+ HFQYN    G  L  +  +     + G+  F + +++K + LY A  +
Sbjct: 151 LLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPF 210

Query: 210 GVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLA-LNQLPQVFSR 268
             +LL   CF           K   FV ++ L  +V     L   PF     Q  QV  R
Sbjct: 211 FCFLL-GKCFKKG-------LKGKGFVLLVKLACIVVASFVLCWLPFFTEREQTLQVLRR 262

Query: 269 LFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTV 328
           LFP  RGL     A N W  +N        + LK+K + P +I        L+  F    
Sbjct: 263 LFPVDRGLFEDKVA-NIWCSFN--------VFLKIKDILPRHIQ-------LIMSF---- 302

Query: 329 LPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLA 388
                       T +++LP+   L  +P   +GF   L  CALS F+F + VHEK+ILL 
Sbjct: 303 ----------CSTFLSLLPACIKLILQPSS-KGFKFTLVSCALSFFLFSFQVHEKSILLV 351

Query: 389 ILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTL 448
            LP+ L+       ++ FL+++T   +S+ PLL     L   ++  + F I  ++S  ++
Sbjct: 352 SLPVCLVLSEIPFMSTWFLLVST---FSMLPLLLKDELLMPSVVTTMAFFIACVTSF-SI 407

Query: 449 FRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPF------------------- 489
           F K       +++F +     L       F F S  ++Y F                   
Sbjct: 408 FEKTSEEELQLKSFSISVRKYLP-----CFTFLSRIIQYLFLISVITMVLLTLMTVTLDP 462

Query: 490 ---IPLLLTSVYCAVG-ITYAWFKLYVSVLI--DSAIGKTKKQ 526
              +P L + + C V  + + +F +Y +++I  DS  G+ +K+
Sbjct: 463 PQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKK 505


>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
          Length = 739

 Score = 32.7 bits (73), Expect = 0.84
 Identities = 21/82 (25%), Positives = 40/82 (48%)

Query: 282 APNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICT 341
           AP F++L  ++  V++++ L+       ++PK    S +        + S   L+T I  
Sbjct: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531

Query: 342 LIAILPSIFCLWFKPQGPRGFL 363
           L+ +  SIFC+  + Q P+  L
Sbjct: 532 LVGVCFSIFCVILRTQKPKSSL 553


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 12/81 (14%)

Query: 110  VIFMDVLFVYAVRECCKCIDGKKVGKE---LTEKPKFILSVLLL--WNFGLLIVDH---- 160
            ++    +F+ A R  C    G++  K+   LT +  F+L +L+   W FGLL V+H    
Sbjct: 2694 IVMNGTMFLLAARTSCST--GQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILA 2751

Query: 161  IHFQYNGFLFGLMLLSIARLF 181
             H+ + G L GL  L++  LF
Sbjct: 2752 FHYLHAG-LCGLQGLAVLLLF 2771


>gi|23503279 transmembrane protein 161B [Homo sapiens]
          Length = 487

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 31/126 (24%), Positives = 53/126 (42%), Gaps = 6/126 (4%)

Query: 261 QLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGL 320
           +L ++ +R+F +   +   Y AP    L+  L  +L  +G     + P +I    + + L
Sbjct: 359 ELQKMVARVFYYLCVIALQYVAPLVMLLHTTL--LLKTLGNHSWGIYPESISTLPVDNSL 416

Query: 321 VQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLT----LCALSSFMF 376
           +    ++ LPS      +  T I +  S     F P   RG L  LT     C  S+ +F
Sbjct: 417 LSNSVYSELPSAEGKMKVTVTQITVALSSLKNIFTPLLFRGLLSFLTWWIAACLFSTSLF 476

Query: 377 GWHVHE 382
           G   H+
Sbjct: 477 GLFYHQ 482


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 21/119 (17%)

Query: 414 HYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVC 473
           H  ++P+ F   E   ++L+++ +++  + S+ TL             F    L   EV 
Sbjct: 148 HAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLI-----------IFGKRTLSNGEVQ 196

Query: 474 CEFVFPFTSWKVKYP--------FIPLLLTSVYCAVGITYAWF--KLYVSVLIDSAIGK 522
           C  ++P  S+   Y         FIPL + S+   + I   W   K Y +V+ + + GK
Sbjct: 197 CWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGK 255


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 21/119 (17%)

Query: 414 HYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVC 473
           H  ++P+ F   E   ++L+++ +++  + S+ TL             F    L   EV 
Sbjct: 148 HAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLI-----------IFGKRTLSNGEVQ 196

Query: 474 CEFVFPFTSWKVKYP--------FIPLLLTSVYCAVGITYAWF--KLYVSVLIDSAIGK 522
           C  ++P  S+   Y         FIPL + S+   + I   W   K Y +V+ + + GK
Sbjct: 197 CWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGK 255


>gi|94538339 signal-regulatory protein gamma isoform 3 precursor
           [Homo sapiens]
          Length = 276

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 323 QFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGP 359
           Q +  +L +V   ATL CT+ ++LP    LWF+  GP
Sbjct: 36  QPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGP 72


>gi|94538337 signal-regulatory protein gamma isoform 2 precursor
           [Homo sapiens]
          Length = 170

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 323 QFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGP 359
           Q +  +L +V   ATL CT+ ++LP    LWF+  GP
Sbjct: 36  QPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGP 72


>gi|94538335 signal-regulatory protein gamma isoform 1 precursor
           [Homo sapiens]
          Length = 387

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 323 QFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGP 359
           Q +  +L +V   ATL CT+ ++LP    LWF+  GP
Sbjct: 36  QPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGP 72


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.143    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,443,423
Number of Sequences: 37866
Number of extensions: 843174
Number of successful extensions: 1882
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1870
Number of HSP's gapped (non-prelim): 12
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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